Rattus norvegicus

27 known processes

Slc5a2

solute carrier family 5 (sodium/glucose cotransporter), member 2

(Aliases: Sglt2)

Slc5a2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203650.791
regulation of ion transportGO:00432692450.706
cation transportGO:00068123820.625
g protein coupled receptor signaling pathwayGO:00071862420.584
cognitionGO:0050890920.485
inorganic ion transmembrane transportGO:00986602290.466
cellular response to oxygen containing compoundGO:19017013860.413
cell cell signalingGO:00072673350.410
synaptic transmissionGO:00072682350.405
positive regulation of ion transportGO:0043270940.394
sodium ion transmembrane transportGO:0035725670.377
negative regulation of multicellular organismal processGO:00512412030.371
homeostatic processGO:00425923310.367
regulation of secretionGO:00510462240.360
positive regulation of transportGO:00510502450.326
secretionGO:00469033070.326
behaviorGO:00076102050.324
nitrogen compound transportGO:00717052290.297
inorganic cation transmembrane transportGO:00986622020.295
response to oxygen levelsGO:00704822650.294
cellular cation homeostasisGO:00300031800.275
negative regulation of cell proliferationGO:00082851190.272
transmembrane transportGO:00550854120.263
regulation of cellular localizationGO:00603412630.242
cation transmembrane transportGO:00986552630.235
lymphocyte activationGO:0046649430.222
regulation of rna biosynthetic processGO:20011413810.213
sodium ion transportGO:0006814820.202
monovalent inorganic cation transportGO:00156721720.201
regulation of tube sizeGO:0035150890.194
regulation of secretion by cellGO:19035302080.193
cellular chemical homeostasisGO:00550822470.184
central nervous system developmentGO:00074173110.174
macromolecular complex subunit organizationGO:00439333390.173
response to hypoxiaGO:00016662310.171
cellular response to organic cyclic compoundGO:00714072020.165
response to decreased oxygen levelsGO:00362932370.163
cellular metal ion homeostasisGO:00068751720.158
metal ion transportGO:00300012890.154
divalent metal ion transportGO:00708381320.153
response to nutrientGO:00075842480.146
positive regulation of multicellular organismal processGO:00512403870.141
positive regulation of secretion by cellGO:19035321280.141
secretion by cellGO:00329402480.138
muscle contractionGO:0006936880.138
organic acid transportGO:00158491160.135
protein complex biogenesisGO:00702712630.135
regulation of transcription dna templatedGO:00063553740.132
sensory perceptionGO:00076001010.130
signal releaseGO:00230611450.128
transcription dna templatedGO:00063513770.127
programmed cell deathGO:00125013920.123
cellular homeostasisGO:00197252520.120
divalent inorganic cation transportGO:00725111340.119
nucleic acid templated transcriptionGO:00976593790.118
response to carbohydrateGO:00097431830.117
regulation of system processGO:00440572080.115
regulation of multicellular organismal developmentGO:20000263760.113
defense responseGO:00069521940.112
regulation of apoptotic processGO:00429813350.111
regulation of body fluid levelsGO:0050878900.110
chemical homeostasisGO:00488782920.103
response to nutrient levelsGO:00316673700.102
cation homeostasisGO:00550801950.102
hormone secretionGO:00468791150.102
regulation of rna metabolic processGO:00512523910.101
cellular ion homeostasisGO:00068731840.101
vesicle mediated transportGO:00161921810.100
ion homeostasisGO:00508012120.096
cellular response to endogenous stimulusGO:00714953770.096
positive regulation of cell communicationGO:00106472710.092
regulation of signal transductionGO:00099663180.092
positive regulation of secretionGO:00510471400.091
negative regulation of apoptotic processGO:00430661810.091
cellular response to nitrogen compoundGO:19016992100.090
inflammatory responseGO:00069541500.090
negative regulation of programmed cell deathGO:00430691830.089
positive regulation of hormone secretionGO:0046887650.088
positive regulation of programmed cell deathGO:00430681570.088
neurological system processGO:00508772190.087
feeding behaviorGO:0007631530.085
regulation of calcium ion transportGO:0051924770.085
negative regulation of response to stimulusGO:00485851550.085
regulation of metal ion transportGO:00109591180.084
anion transportGO:00068201780.084
muscle system processGO:00030121150.082
regulation of peptide hormone secretionGO:0090276800.082
regulation of cell differentiationGO:00455953200.081
response to estrogenGO:00436272320.081
cellular amino acid metabolic processGO:00065201070.081
regulation of anion transportGO:0044070430.076
agingGO:00075682410.076
macromolecular complex assemblyGO:00650032730.076
smooth muscle contractionGO:0006939370.075
organic acid metabolic processGO:00060822920.075
cellular response to steroid hormone stimulusGO:0071383930.075
regulation of cell proliferationGO:00421273590.074
regulation of blood vessel sizeGO:0050880890.074
transmission of nerve impulseGO:0019226420.074
circulatory system developmentGO:00723591340.074
regulation of behaviorGO:0050795610.074
regulation of hormone secretionGO:00468831060.073
response to extracellular stimulusGO:00099913800.073
positive regulation of amine transportGO:0051954260.072
transcription from rna polymerase ii promoterGO:00063662520.072
regulation of cellular ketone metabolic processGO:0010565270.071
positive regulation of protein phosphorylationGO:00019341350.071
response to inorganic substanceGO:00100353770.071
negative regulation of signalingGO:00230571570.071
calcium ion transportGO:00068161310.070
negative regulation of nitrogen compound metabolic processGO:00511721610.070
positive regulation of calcium ion transportGO:0051928360.069
regulation of phosphate metabolic processGO:00192203490.068
carbohydrate derivative metabolic processGO:19011353460.067
positive regulation of biosynthetic processGO:00098913190.067
regulation of programmed cell deathGO:00430673410.067
response to alkaloidGO:00432791320.066
protein complex assemblyGO:00064612630.065
learning or memoryGO:0007611900.064
apoptotic processGO:00069153810.064
cellular component assemblyGO:00226073600.063
cellular component biogenesisGO:00440853680.062
regulation of nervous system developmentGO:00519602640.060
positive regulation of immune system processGO:0002684900.060
somatostatin receptor signaling pathwayGO:003816940.060
positive regulation of protein metabolic processGO:00512471780.060
positive regulation of peptide secretionGO:0002793520.058
multicellular organism reproductionGO:00325042330.058
protein complex subunit organizationGO:00718223020.058
regulation of cellular component organizationGO:00511283680.058
negative regulation of secretionGO:0051048820.057
response to metal ionGO:00100382530.056
cellular response to lipidGO:00713962010.056
response to hexoseGO:00097461440.056
insulin secretionGO:0030073690.055
regulation of transmembrane transportGO:00347621220.055
calcium ion importGO:0070509220.055
regulation of anatomical structure sizeGO:00900661350.054
positive regulation of signal transductionGO:00099671750.054
regulation of phosphorus metabolic processGO:00511743490.053
hormone transportGO:00099141210.053
negative regulation of cell deathGO:00605482290.053
neuropeptide signaling pathwayGO:0007218290.053
positive regulation of phosphorus metabolic processGO:00105622620.053
peptide secretionGO:0002790860.053
glucose homeostasisGO:0042593750.053
regulation of locomotionGO:00400121480.053
monoamine transportGO:0015844430.052
multicellular organismal response to stressGO:0033555250.051
cellular response to organonitrogen compoundGO:00714171970.050
positive regulation of synaptic transmissionGO:0050806620.050
regulation of hormone levelsGO:00108171870.050
positive regulation of developmental processGO:00510942830.050
nucleotide metabolic processGO:00091172790.050
behavioral response to painGO:004826650.049
calcium ion homeostasisGO:00550741620.048
response to acid chemicalGO:00011012220.048
regulation of neurogenesisGO:00507672470.048
rna metabolic processGO:00160704060.047
cardiovascular system developmentGO:00723581340.046
regulation of blood pressureGO:0008217830.046
metal ion homeostasisGO:00550651860.045
alpha amino acid metabolic processGO:1901605710.044
response to ammonium ionGO:0060359710.044
regulation of peptide transportGO:0090087870.044
positive regulation of signalingGO:00230562700.044
negative regulation of homeostatic processGO:0032845470.044
single organism reproductive processGO:00447022970.044
positive regulation of response to stimulusGO:00485842850.044
response to glucoseGO:00097491360.043
growthGO:00400071650.043
regulation of homeostatic processGO:00328441010.042
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.042
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.041
regulation of neuron differentiationGO:00456642080.041
protein oligomerizationGO:00512591910.041
calcium ion transport into cytosolGO:0060402380.041
regulation of membrane potentialGO:00423911100.040
cellular calcium ion homeostasisGO:00068741600.040
head developmentGO:00603222470.040
positive regulation of serotonin secretionGO:001406410.040
reproductionGO:00000032450.040
negative regulation of transportGO:00510511360.039
cellular response to peptideGO:19016531330.039
erk1 and erk2 cascadeGO:0070371480.038
positive regulation of nitrogen compound metabolic processGO:00511733340.038
hormone mediated signaling pathwayGO:0009755230.038
regulation of cellular amine metabolic processGO:003323880.038
response to monosaccharideGO:00342841590.038
rna biosynthetic processGO:00327743800.038
vascular process in circulatory systemGO:0003018960.037
renal system processGO:0003014400.037
cellular response to abiotic stimulusGO:0071214850.037
carboxylic acid transportGO:00469421150.037
neuron neuron synaptic transmissionGO:0007270600.036
mapk cascadeGO:00001651400.036
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.036
positive regulation of response to foodGO:003209730.036
male mating behaviorGO:006017930.036
positive regulation of macromolecule biosynthetic processGO:00105572470.035
regulation of nucleic acid templated transcriptionGO:19035063800.035
carbohydrate homeostasisGO:0033500750.035
ribose phosphate metabolic processGO:00196932350.035
regulation of catalytic activityGO:00507903040.035
positive regulation of cell proliferationGO:00082842490.034
response to woundingGO:00096112540.034
multicellular organismal water homeostasisGO:005089140.034
single organism behaviorGO:00447081300.034
regulation of transferase activityGO:00513381230.034
response to estradiolGO:00323551640.034
regulation of protein modification processGO:00313991940.034
cellular response to glucose stimulusGO:0071333650.034
oxoacid metabolic processGO:00434362900.034
response to painGO:0048265110.033
negative regulation of chronic inflammatory responseGO:000267720.033
positive regulation of rna metabolic processGO:00512542030.033
regulation of response to external stimulusGO:00321011060.033
response to ethanolGO:00454711620.033
anion transmembrane transportGO:0098656770.033
sequestering of calcium ionGO:005120880.032
blood circulationGO:00080151830.032
multi organism reproductive processGO:00447032620.032
cellular response to hexose stimulusGO:0071331650.032
organophosphate metabolic processGO:00196373700.031
positive regulation of rna biosynthetic processGO:19026801970.031
positive regulation of molecular functionGO:00440932300.031
protein homooligomerizationGO:0051260910.031
nucleoside phosphate metabolic processGO:00067532830.031
multicellular organismal reproductive processGO:00486092330.031
negative regulation of secretion by cellGO:1903531720.030
reproductive processGO:00224143720.030
cellular response to stressGO:00335542690.030
positive regulation of blood circulationGO:1903524650.030
peptide transportGO:0015833970.030
organic substance catabolic processGO:19015753160.030
regulation of transcription from rna polymerase ii promoterGO:00063572340.029
regulation of cell projection organizationGO:00313441750.029
regulation of leukocyte activationGO:0002694450.029
cytoplasmic transportGO:00164821150.029
regulation of cytokine productionGO:0001817560.029
cell type specific apoptotic processGO:00972851340.029
cellular response to external stimulusGO:00714961180.029
regulation of defecationGO:200029210.029
negative regulation of cell communicationGO:00106481580.029
negative regulation of signal transductionGO:0009968830.029
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.029
regulation of ion transmembrane transportGO:00347651210.029
response to peptideGO:19016522920.028
regulation of protein metabolic processGO:00512462890.028
positive regulation of cell activationGO:0050867340.028
memoryGO:0007613540.028
positive regulation of phosphate metabolic processGO:00459372620.028
sequestering of metal ionGO:005123890.028
response to amphetamineGO:0001975250.027
serotonin secretionGO:000182060.027
negative regulation of follicle stimulating hormone secretionGO:004688230.027
regulation of blood circulationGO:19035221100.027
negative regulation of calcium ion importGO:009028120.027
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.027
maintenance of locationGO:0051235170.026
regulation of phosphorylationGO:00423252480.026
regulation of ion homeostasisGO:2000021630.026
copulationGO:0007620170.026
circulatory system processGO:00030131830.026
regulation of cellular amino acid metabolic processGO:000652120.026
positive regulation of cellular biosynthetic processGO:00313282950.026
heart processGO:0003015570.026
amine transportGO:0015837570.025
intracellular transportGO:00469071850.025
action potentialGO:0001508540.025
positive regulation of gene expressionGO:00106282440.025
negative regulation of biosynthetic processGO:00098901680.025
purine nucleotide biosynthetic processGO:0006164830.025
single organism catabolic processGO:00447122830.025
regulation of cyclic nucleotide biosynthetic processGO:0030802450.025
ribose phosphate biosynthetic processGO:0046390870.025
positive regulation of cellular amino acid metabolic processGO:004576410.025
norepinephrine secretionGO:0048243160.025
locomotionGO:00400112370.024
sensory perception of painGO:0019233730.024
amide transportGO:00428861050.024
positive regulation of purine nucleotide biosynthetic processGO:1900373360.024
neuron differentiationGO:00301823680.024
regulation of insulin secretionGO:0050796650.024
cellular response to glucocorticoid stimulusGO:0071385680.024
nucleobase containing small molecule metabolic processGO:00550863160.024
positive regulation of peptide hormone secretionGO:0090277500.024
regulation of cellular component movementGO:00512701500.023
regulation of cyclic nucleotide metabolic processGO:0030799510.023
response to foodGO:0032094270.023
regulation of synaptic transmissionGO:00508041410.023
protein localizationGO:00081041910.023
cytosolic calcium ion transportGO:0060401390.023
positive regulation of transcription dna templatedGO:00458931970.023
positive regulation of leukocyte activationGO:0002696300.023
leukocyte activationGO:0045321760.023
response to growth factorGO:00708481890.023
response to ketoneGO:19016541820.023
organ morphogenesisGO:0009887750.023
gastric inhibitory peptide signaling pathwayGO:003819210.022
negative regulation of defecationGO:200029310.022
heart contractionGO:0060047570.022
regulation of action potentialGO:0098900140.022
catabolic processGO:00090563510.022
negative regulation of gene expressionGO:00106291990.022
brain developmentGO:00074202470.022
organic anion transportGO:00157111320.021
negative regulation of luteinizing hormone secretionGO:003368540.021
regulation of response to woundingGO:1903034690.021
positive regulation of cellular amine metabolic processGO:003324030.021
cellular response to peptide hormone stimulusGO:00713751200.021
negative regulation of cell developmentGO:0010721820.021
positive regulation of phosphorylationGO:00423271770.021
intracellular signal transductionGO:00355563140.021
epithelial cell proliferationGO:0050673540.021
positive regulation of nucleic acid templated transcriptionGO:19035081970.021
regulation of immune system processGO:00026821230.021
somatostatin signaling pathwayGO:003817040.021
negative regulation of cell differentiationGO:0045596990.021
nucleotide biosynthetic processGO:0009165980.021
renal system developmentGO:0072001670.021
cyclic nucleotide biosynthetic processGO:0009190630.021
urinary bladder smooth muscle contractionGO:001483240.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
cell motilityGO:00488702020.020
negative regulation of behaviorGO:0048521180.020
cellular response to acid chemicalGO:0071229750.020
organic cyclic compound catabolic processGO:19013611750.020
regulation of peptide secretionGO:0002791820.020
positive regulation of catalytic activityGO:00430851840.020
smooth muscle cell proliferationGO:0048659770.020
ribonucleotide metabolic processGO:00092592310.020
aromatic amino acid family metabolic processGO:000907290.020
release of sequestered calcium ion into cytosolGO:0051209250.020
regulation of intracellular transportGO:0032386650.020
regulation of protein phosphorylationGO:00019321830.019
alpha amino acid catabolic processGO:1901606200.019
positive regulation of cyclic nucleotide metabolic processGO:0030801370.019
forebrain developmentGO:0030900980.019
cellular response to cytokine stimulusGO:00713451270.019
negative regulation of cellular biosynthetic processGO:00313271610.019
organic hydroxy compound transportGO:0015850770.019
response to cocaineGO:0042220390.019
negative regulation of nucleobase containing compound metabolic processGO:00459341530.019
single organism intracellular transportGO:19025821660.019
sodium ion homeostasisGO:0055078230.019
acid secretionGO:0046717480.019
regulation of neuron deathGO:19012141150.019
exocytosisGO:0006887600.019
purine containing compound metabolic processGO:00725212530.019
multicellular organismal signalingGO:0035637440.019
positive regulation of cytosolic calcium ion concentrationGO:00072041220.018
regulation of cellular protein metabolic processGO:00322682670.018
second messenger mediated signalingGO:0019932510.018
cell migrationGO:00164771970.018
regulation of heart rateGO:0002027160.018
regulation of excretionGO:0044062210.018
regulation of cellular component biogenesisGO:0044087860.018
positive regulation of cellular component organizationGO:00511302000.018
response to calcium ionGO:0051592590.018
peptide hormone secretionGO:0030072840.017
localization of cellGO:00516742020.017
purine nucleotide metabolic processGO:00061632290.017
positive regulation of nucleotide metabolic processGO:0045981910.017
actin cytoskeleton organizationGO:0030036730.017
regulation of cell motilityGO:20001451310.017
regulation of organic acid transportGO:0032890350.017
anatomical structure morphogenesisGO:00096532980.017
nucleoside phosphate biosynthetic processGO:19012931020.017
positive regulation of muscle contractionGO:0045933220.017
epithelium developmentGO:0060429960.017
positive regulation of cell differentiationGO:00455972170.017
negative regulation of macromolecule metabolic processGO:00106052600.017
dicarboxylic acid transportGO:0006835340.017
regulation of cell morphogenesis involved in differentiationGO:0010769720.017
ribonucleotide biosynthetic processGO:0009260850.017
cellular amine metabolic processGO:0044106380.017
response to amineGO:0014075460.017
negative regulation of developmental processGO:00510931250.017
regulation of cell developmentGO:00602842630.017
regulation of growthGO:00400081050.016
establishment of protein localizationGO:00451841410.016
positive regulation of protein modification processGO:00314011420.016
regulation of synaptic plasticityGO:0048167700.016
regulation of neuron projection developmentGO:00109751610.016
regulation of anatomical structure morphogenesisGO:00226031410.016
response to purine containing compoundGO:00140741260.016
regulation of defense responseGO:0031347680.016
regulation of vesicle mediated transportGO:0060627810.016
regulation of cell migrationGO:00303341280.016
negative regulation of cellular metabolic processGO:00313242810.016
phasic smooth muscle contractionGO:001482130.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
excretionGO:0007588240.016
regulation of muscle contractionGO:0006937530.016
positive regulation of immunoglobulin productionGO:000263940.016
defecationGO:003042110.016
purine containing compound biosynthetic processGO:0072522850.016
response to corticosteroidGO:00319602350.016
response to corticosteroneGO:0051412400.015
peptidyl amino acid modificationGO:00181931260.015
cellular glucose homeostasisGO:0001678660.015
actin filament organizationGO:0007015420.015
cellular response to carbohydrate stimulusGO:0071322720.015
regulation of intracellular signal transductionGO:19025312180.015
single organism organelle organizationGO:19025891800.015
ossificationGO:0001503700.015
cellular ketone metabolic processGO:0042180510.015
cellular response to monosaccharide stimulusGO:0071326670.015
positive regulation of cell migrationGO:0030335960.015
immune system processGO:00023762040.015
organonitrogen compound biosynthetic processGO:19015661670.015
retina development in camera type eyeGO:0060041270.015
cell activationGO:0001775970.015
developmental process involved in reproductionGO:00030061590.015
regulation of purine nucleotide metabolic processGO:19005421150.015
smooth muscle cell migrationGO:0014909360.014
neuronal action potentialGO:0019228350.014
carboxylic acid biosynthetic processGO:0046394830.014
locomotory exploration behaviorGO:003564110.014
sexual reproductionGO:00199531480.014
negative regulation of smooth muscle cell proliferationGO:0048662210.014
regulation of smooth muscle cell proliferationGO:0048660750.014
response to molecule of bacterial originGO:00022371940.014
regulation of norepinephrine secretionGO:0014061150.014
response to glucocorticoidGO:00513842230.014
cardiac conductionGO:006133720.014
neurotransmitter uptakeGO:000150430.014
positive regulation of kinase activityGO:0033674770.014
organelle organizationGO:00069962660.014
epithelial cell differentiationGO:0030855710.014
response to osmotic stressGO:0006970420.014
regulation of inflammatory responseGO:0050727480.014
positive regulation of amino acid transportGO:0051957130.014
peristalsisGO:003043220.014
visual learningGO:000854280.014
choline transportGO:001587140.014
palate developmentGO:006002120.014
proteolysisGO:00065081750.013
negative regulation of neuron deathGO:1901215690.013
synaptic vesicle transportGO:0048489230.013
regulation of heart contractionGO:0008016480.013
positive regulation of isotype switchingGO:004583010.013
response to cgmpGO:007030530.013
negative regulation of transcription dna templatedGO:00458921160.013
cellular response to hormone stimulusGO:00328702470.013
small gtpase mediated signal transductionGO:0007264360.013
regulation of mapk cascadeGO:00434081160.013
inorganic anion transportGO:0015698410.013
response to axon injuryGO:0048678590.013
negative regulation of long term synaptic potentiationGO:190027210.013
catecholamine transportGO:0051937370.013
negative regulation of rna metabolic processGO:00512531230.013
l amino acid transportGO:0015807210.013
tissue morphogenesisGO:0048729220.013
purine ribonucleotide metabolic processGO:00091502270.013
sperm ejaculationGO:004271350.013
regulation of nucleotide metabolic processGO:00061401170.013
positive regulation of mast cell activationGO:003300540.013
response to electrical stimulusGO:0051602560.013
gliogenesisGO:0042063930.013
serotonin transportGO:000683790.012
stress activated mapk cascadeGO:0051403350.012
neural crest cell developmentGO:001403220.012
cytosolic calcium ion homeostasisGO:00514801400.012
positive regulation of leukocyte degranulationGO:004330240.012
cytokine productionGO:0001816610.012
regulation of response to stressGO:00801341260.012
response to amino acidGO:0043200750.012
negative regulation of nervous system developmentGO:0051961790.012
b cell activation involved in immune responseGO:000231210.012
regulation of interleukin 6 productionGO:0032675120.012
regulation of molecular functionGO:00650093980.012
regulation of immunoglobulin productionGO:000263740.012
positive regulation of cell motilityGO:2000147970.012
negative regulation of metabolic processGO:00098923310.012
multi multicellular organism processGO:00447061380.012
regulation of glutamate secretionGO:0014048170.012
triglyceride homeostasisGO:007032820.012
cytokine mediated signaling pathwayGO:0019221430.012
cyclic purine nucleotide metabolic processGO:0052652620.012
regulation of establishment of protein localizationGO:0070201690.012
positive regulation of smooth muscle contractionGO:0045987180.012
negative regulation of response to external stimulusGO:0032102370.012
response to retinoic acidGO:0032526630.012
vesicle localizationGO:0051648330.012
signal transduction by phosphorylationGO:00230141440.012
regulation of epithelial cell proliferationGO:0050678490.012
regulation of amine transportGO:0051952540.012
positive regulation of nucleobase containing compound metabolic processGO:00459353190.011

Slc5a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.792
Human
disease of anatomical entityDOID:700.792
Human
kidney diseaseDOID:55700.259
Human
nervous system diseaseDOID:86300.017
musculoskeletal system diseaseDOID:1700.016
connective tissue diseaseDOID:6500.012