Rattus norvegicus

0 known processes

Syt11

synaptotagmin XI

Syt11 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sodium ion transmembrane transportGO:0035725670.494
synaptic vesicle exocytosisGO:0016079150.386
Rat
cation transportGO:00068123820.378
cation transmembrane transportGO:00986552630.332
synaptic vesicle endocytosisGO:004848840.326
protein complex biogenesisGO:00702712630.318
synaptic transmissionGO:00072682350.299
Rat
sodium ion transportGO:0006814820.292
synaptic vesicle localizationGO:0097479240.292
Rat
neuron differentiationGO:00301823680.264
synaptic vesicle transportGO:0048489230.250
Rat
regulation of neurotransmitter secretionGO:0046928190.249
Rat
protein complex subunit organizationGO:00718223020.242
cellular component biogenesisGO:00440853680.227
organelle organizationGO:00069962660.214
Yeast Rat
neuron developmentGO:00486662860.213
cellular component assemblyGO:00226073600.202
regulation of synaptic vesicle exocytosisGO:200030060.190
Rat
regulation of synaptic transmissionGO:00508041410.177
Rat
macromolecular complex subunit organizationGO:00439333390.164
monovalent inorganic cation transportGO:00156721720.153
macromolecular complex assemblyGO:00650032730.152
neurotransmitter transportGO:0006836420.145
Rat
axon developmentGO:0061564960.144
neuron projection developmentGO:00311752730.131
localization of cellGO:00516742020.128
protein complex assemblyGO:00064612630.123
transmembrane transportGO:00550854120.122
establishment of organelle localizationGO:0051656370.121
Rat
establishment of vesicle localizationGO:0051650310.112
Rat
regulation of cell morphogenesis involved in differentiationGO:0010769720.111
phosphatidylinositol dephosphorylationGO:004685640.110
Yeast
negative regulation of vesicle fusionGO:003133920.110
Rat
exocytosisGO:0006887600.109
Rat
metal ion transportGO:00300012890.103
cellular component movementGO:00069282480.102
positive regulation of transportGO:00510502450.099
Rat
cell morphogenesis involved in neuron differentiationGO:00486671060.098
neurotransmitter secretionGO:0007269330.098
Rat
membrane fusionGO:0061025260.096
Rat
membrane depolarization during cardiac muscle cell action potentialGO:008601210.096
organophosphate metabolic processGO:00196373700.095
Yeast
macromolecule localizationGO:00330362520.094
neurological system processGO:00508772190.093
inorganic cation transmembrane transportGO:00986622020.092
regulation of cellular component organizationGO:00511283680.090
Rat
cell cell signalingGO:00072673350.090
Rat
axonogenesisGO:0007409710.088
inorganic ion transmembrane transportGO:00986602290.087
cell migrationGO:00164771970.086
regulation of vesicle mediated transportGO:0060627810.086
Rat
protein heterooligomerizationGO:0051291890.086
regulation of catalytic activityGO:00507903040.086
ribonucleotide metabolic processGO:00092592310.082
response to radiationGO:00093141370.081
regulation of phosphate metabolic processGO:00192203490.077
Yeast
vesicle mediated transportGO:00161921810.076
Rat
nitrogen compound transportGO:00717052290.075
Rat
brain developmentGO:00074202470.073
regulation of cell motilityGO:20001451310.073
central nervous system developmentGO:00074173110.071
single organism organelle organizationGO:19025891800.071
Rat
cellular metal ion homeostasisGO:00068751720.069
synaptic growth at neuromuscular junctionGO:005112410.069
vesicle dockingGO:004827850.068
Rat
vesicle organizationGO:0016050290.067
Rat
positive regulation of multicellular organismal processGO:00512403870.065
divalent metal ion transportGO:00708381320.064
regulation of rna metabolic processGO:00512523910.064
cellular amino acid metabolic processGO:00065201070.062
amino acid transportGO:0006865700.061
organelle localizationGO:0051640550.061
Rat
secretionGO:00469033070.061
Rat
intracellular signal transductionGO:00355563140.060
cell projection organizationGO:00300303020.060
receptor mediated endocytosisGO:0006898420.059
chemotaxisGO:0006935660.059
apoptotic processGO:00069153810.059
regulation of exocytosisGO:0017157370.058
Rat
vesicle localizationGO:0051648330.058
Rat
ion transmembrane transportGO:00342203650.058
regulation of signal transductionGO:00099663180.057
positive regulation of cell projection organizationGO:00313461110.057
locomotionGO:00400112370.057
protein oligomerizationGO:00512591910.057
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.056
regulation of molecular functionGO:00650093980.056
glial cell differentiationGO:0010001650.055
single organism catabolic processGO:00447122830.055
purine containing compound metabolic processGO:00725212530.053
response to histamineGO:003477630.053
regulation of multicellular organismal developmentGO:20000263760.053
positive regulation of synaptic vesicle transportGO:190280530.053
biological adhesionGO:00226101100.053
negative regulation of macromolecule metabolic processGO:00106052600.052
heart processGO:0003015570.051
signal releaseGO:00230611450.051
Rat
positive regulation of exocytosisGO:0045921190.050
Rat
regulation of neuron deathGO:19012141150.048
regulation of phosphorus metabolic processGO:00511743490.048
Yeast
response to inorganic substanceGO:00100353770.047
Rat
regulation of cell differentiationGO:00455953200.047
anion transmembrane transportGO:0098656770.046
secretion by cellGO:00329402480.046
Rat
membrane organizationGO:0061024940.046
Yeast Rat
divalent inorganic cation transportGO:00725111340.046
positive regulation of cellular component organizationGO:00511302000.045
Rat
single organism membrane organizationGO:0044802740.045
Yeast Rat
amine metabolic processGO:0009308380.044
cellular component morphogenesisGO:00329891550.044
regulation of synaptic plasticityGO:0048167700.044
regulation of cellular localizationGO:00603412630.043
Rat
regulation of neuron differentiationGO:00456642080.041
purine nucleoside triphosphate catabolic processGO:00091461220.041
synapse organizationGO:0050808460.041
response to alkaloidGO:00432791320.041
ras protein signal transductionGO:0007265290.040
positive regulation of nucleobase containing compound metabolic processGO:00459353190.040
cell projection morphogenesisGO:00488581230.040
response to insecticideGO:0017085210.040
purine nucleotide metabolic processGO:00061632290.040
endocytosisGO:0006897840.039
rho protein signal transductionGO:0007266110.039
blood circulationGO:00080151830.039
calcium ion dependent exocytosis of neurotransmitterGO:004879120.039
negative regulation of exocytosisGO:004592070.039
Rat
regulation of secretionGO:00510462240.039
Rat
regulation of anatomical structure morphogenesisGO:00226031410.038
cellular protein localizationGO:00346131220.038
small gtpase mediated signal transductionGO:0007264360.038
ribose phosphate metabolic processGO:00196932350.038
positive regulation of phosphate metabolic processGO:00459372620.037
regulation of ion transmembrane transportGO:00347651210.037
negative regulation of nervous system developmentGO:0051961790.037
response to transition metal nanoparticleGO:19902671220.037
nucleoside phosphate catabolic processGO:19012921400.036
regulation of sodium ion transportGO:0002028210.036
g protein coupled receptor signaling pathwayGO:00071862420.036
anatomical structure morphogenesisGO:00096532980.035
striated muscle contractionGO:0006941440.035
establishment of synaptic vesicle localizationGO:0097480230.035
Rat
regulation of locomotionGO:00400121480.035
regulation of cellular amine metabolic processGO:003323880.034
neuron projection guidanceGO:0097485240.034
regulation of cell morphogenesisGO:0022604770.034
gliogenesisGO:0042063930.034
purine ribonucleotide metabolic processGO:00091502270.033
developmental process involved in reproductionGO:00030061590.033
oxoacid metabolic processGO:00434362900.033
positive regulation of organelle organizationGO:0010638480.033
Rat
regulation of ion transportGO:00432692450.032
circulatory system processGO:00030131830.032
regulation of cellular ketone metabolic processGO:0010565270.032
protein phosphorylationGO:00064683450.032
negative regulation of cell communicationGO:00106481580.032
rna metabolic processGO:00160704060.032
regulation of circadian sleep wake cycle sleepGO:0045187180.031
cell morphogenesis involved in differentiationGO:00009041190.031
nucleoside phosphate metabolic processGO:00067532830.031
regulation of phosphorylationGO:00423252480.031
regulation of cellular component movementGO:00512701500.031
regulation of programmed cell deathGO:00430673410.031
organelle fusionGO:0048284170.031
Rat
regulation of neurogenesisGO:00507672470.031
positive regulation of catalytic activityGO:00430851840.031
organonitrogen compound catabolic processGO:19015651790.030
synaptic transmission glycinergicGO:006001220.030
negative regulation of response to stimulusGO:00485851550.030
regulation of cellular protein metabolic processGO:00322682670.030
synaptic vesicle primingGO:001608240.030
regulation of membrane potentialGO:00423911100.030
regulation of protein phosphorylationGO:00019321830.029
cellular nitrogen compound catabolic processGO:00442701630.029
actin filament based processGO:0030029860.029
defecationGO:003042110.029
taxisGO:0042330670.029
muscle system processGO:00030121150.029
regulation of neuron projection developmentGO:00109751610.029
rhythmic synaptic transmissionGO:006002410.029
glutamate receptor signaling pathwayGO:0007215430.029
regulation of nucleotide metabolic processGO:00061401170.028
carboxylic acid metabolic processGO:00197522890.028
positive regulation of cell differentiationGO:00455972170.028
agingGO:00075682410.028
organophosphate catabolic processGO:00464341480.028
nucleobase containing small molecule metabolic processGO:00550863160.028
neuromuscular synaptic transmissionGO:000727420.028
single organism cellular localizationGO:19025801020.028
transcription dna templatedGO:00063513770.027
rhythmic processGO:00485111560.027
regulation of sodium ion transmembrane transporter activityGO:200064940.027
positive regulation of ion transportGO:0043270940.027
negative regulation of secretion by cellGO:1903531720.027
Rat
neuron deathGO:00709971270.027
regulation of synaptic vesicle transportGO:190280360.027
Rat
heart morphogenesisGO:000300730.026
positive regulation of secretionGO:00510471400.026
Rat
development of primary sexual characteristicsGO:00451371070.026
cell part morphogenesisGO:00329901230.026
purine containing compound catabolic processGO:00725231380.026
regulation of peptide secretionGO:0002791820.026
Rat
positive regulation of neurotransmitter secretionGO:000195690.026
cellular response to histamineGO:007142030.026
cellular amine metabolic processGO:0044106380.026
protein localizationGO:00081041910.026
regulation of intracellular signal transductionGO:19025312180.026
sensory perception of painGO:0019233730.025
positive regulation of developmental processGO:00510942830.025
g protein coupled glutamate receptor signaling pathwayGO:000721680.025
regulation of cellular amino acid metabolic processGO:000652120.025
growthGO:00400071650.025
regulation of cell developmentGO:00602842630.025
positive regulation of programmed cell deathGO:00430681570.025
carboxylic acid transportGO:00469421150.024
regulation of cell migrationGO:00303341280.024
organic acid metabolic processGO:00060822920.024
circadian rhythmGO:0007623880.024
positive regulation of molecular functionGO:00440932300.024
single organism reproductive processGO:00447022970.024
response to light stimulusGO:0009416520.024
asymmetric protein localizationGO:000810520.023
positive regulation of cellular amine metabolic processGO:003324030.023
neuromuscular processGO:005090520.023
detection of stimulusGO:0051606240.023
Rat
cytoskeleton organizationGO:00070101110.023
actin filament based movementGO:0030048160.023
regulation of cell projection organizationGO:00313441750.023
regulation of transmembrane transportGO:00347621220.023
response to ammonium ionGO:0060359710.023
endoplasmic reticulum organizationGO:000702910.023
Yeast
nucleoside triphosphate catabolic processGO:00091431230.023
reproductive processGO:00224143720.023
regulation of axon extensionGO:0030516240.022
positive regulation of cell deathGO:00109421840.022
nucleotide metabolic processGO:00091172790.022
negative regulation of cellular metabolic processGO:00313242810.022
circadian sleep wake cycle sleepGO:0050802210.022
response to toxic substanceGO:00096361330.022
actin mediated cell contractionGO:0070252120.022
ribonucleoside metabolic processGO:00091191740.022
negative regulation of cellular component organizationGO:0051129830.021
Rat
positive regulation of nervous system developmentGO:00519621780.021
positive regulation of neurogenesisGO:00507691650.021
response to mechanical stimulusGO:00096121340.021
regulation of ion transmembrane transporter activityGO:0032412480.021
regulation of developmental growthGO:0048638450.021
negative regulation of developmental processGO:00510931250.021
regulation of peptide transportGO:0090087870.021
Rat
sex differentiationGO:00075481130.021
ribonucleoside catabolic processGO:00424541260.021
cell adhesionGO:00071551100.021
reactive oxygen species biosynthetic processGO:190340980.021
regulation of anatomical structure sizeGO:00900661350.021
organic cyclic compound catabolic processGO:19013611750.021
positive regulation of cell developmentGO:00107201760.021
neuronal ion channel clusteringGO:004516130.020
cell morphogenesisGO:00009021420.020
homeostatic processGO:00425923310.020
regulation of regulated secretory pathwayGO:190330570.020
Rat
protein localization to membraneGO:0072657360.020
positive regulation of neuron projection developmentGO:0010976990.020
regulation of organelle organizationGO:0033043800.020
Rat
protein tetramerizationGO:0051262380.020
cellular macromolecule localizationGO:00707271220.020
detection of calcium ionGO:000551310.020
Rat
calcium ion transmembrane transportGO:0070588700.020
carbohydrate derivative metabolic processGO:19011353460.019
regulation of cellular component biogenesisGO:0044087860.019
negative regulation of signalingGO:00230571570.019
gastric motilityGO:003548230.019
neurotransmitter gated ion channel clusteringGO:007257830.019
respiratory system processGO:000301630.019
forebrain developmentGO:0030900980.019
nucleoside metabolic processGO:00091161790.019
cell fate commitment involved in pattern specificationGO:006058120.019
regulation of receptor mediated endocytosisGO:0048259170.019
negative regulation of gene expressionGO:00106291990.019
sensory perceptionGO:00076001010.019
head developmentGO:00603222470.019
single organism behaviorGO:00447081300.018
chemical homeostasisGO:00488782920.018
neuron apoptotic processGO:0051402880.018
cell motilityGO:00488702020.018
positive regulation of phosphorus metabolic processGO:00105622620.017
multicellular organism growthGO:003526410.017
cell cycleGO:00070491010.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
negative regulation of cellular protein metabolic processGO:00322691060.017
negative regulation of catalytic activityGO:00430861030.017
negative regulation of cell deathGO:00605482290.017
positive regulation of apoptotic processGO:00430651540.017
neuron projection morphogenesisGO:00488121220.017
developmental growthGO:00485891000.016
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.016
positive regulation of cellular component biogenesisGO:0044089550.016
circadian behaviorGO:0048512240.016
membrane depolarizationGO:0051899320.016
cardiac muscle contractionGO:0060048270.016
regulation of phosphatidylinositol dephosphorylationGO:006030410.016
Yeast
negative regulation of calcium ion dependent exocytosisGO:004595550.016
Rat
regenerationGO:00310991630.016
aromatic compound catabolic processGO:00194391680.016
regulation of protein metabolic processGO:00512462890.016
positive regulation of inhibitory postsynaptic membrane potentialGO:009715130.016
cell activationGO:0001775970.016
vesicle fusionGO:0006906140.016
Rat
positive regulation of secretion by cellGO:19035321280.016
Rat
anion transportGO:00068201780.016
regulation of actin filament based processGO:0032970420.016
reproductive system developmentGO:00614581280.016
ribonucleoside triphosphate metabolic processGO:00091991410.016
cell growthGO:00160491040.016
regulation of hydrolase activityGO:00513361430.015
regulation of extent of cell growthGO:0061387250.015
n methyl d aspartate receptor clusteringGO:009711420.015
dopamine secretionGO:0014046150.015
negative regulation of cell developmentGO:0010721820.015
regulation of nucleic acid templated transcriptionGO:19035063800.015
nucleotide catabolic processGO:00091661390.015
gonad developmentGO:00084061040.015
cellular macromolecular complex assemblyGO:0034622580.015
regulation of transmembrane transporter activityGO:0022898490.015
adult locomotory behaviorGO:000834440.015
embryonic pattern specificationGO:000988010.015
membrane depolarization during action potentialGO:008601010.015
negative regulation of transportGO:00510511360.015
Rat
negative regulation of protein metabolic processGO:00512481140.015
response to growth factorGO:00708481890.015
regulation of homeostatic processGO:00328441010.015
catabolic processGO:00090563510.015
calcium ion dependent exocytosisGO:0017156160.015
Rat
axon guidanceGO:0007411240.015
positive regulation of cell communicationGO:00106472710.015
purine nucleoside metabolic processGO:00422781690.015
regulation of cytoskeleton organizationGO:0051493490.015
response to ethanolGO:00454711620.015
positive regulation of protein metabolic processGO:00512471780.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
negative regulation of cell differentiationGO:0045596990.014
axis specificationGO:000979840.014
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.014
rna biosynthetic processGO:00327743800.014
rhythmic behaviorGO:0007622240.014
negative regulation of epinephrine secretionGO:003281160.014
positive regulation of cytoskeleton organizationGO:0051495260.014
nucleic acid templated transcriptionGO:00976593790.014
tissue developmentGO:00098882520.014
regulation of neuronal synaptic plasticityGO:0048168310.014
associative learningGO:0008306190.014
positive regulation of protein modification processGO:00314011420.014
multicellular organismal reproductive processGO:00486092330.014
regulation of neurotransmitter levelsGO:0001505420.014
Rat
regulation of cell sizeGO:0008361370.014
anterior posterior pattern specificationGO:000995210.014
multicellular organism reproductionGO:00325042330.014
cell communication involved in cardiac conductionGO:008606520.014
monocarboxylic acid transportGO:0015718520.014
single organism intracellular transportGO:19025821660.013
organic hydroxy compound metabolic processGO:19016151150.013
endomembrane system organizationGO:0010256480.013
Yeast
positive regulation of nitrogen compound metabolic processGO:00511733340.013
regulation of transcription dna templatedGO:00063553740.013
cardiac muscle cell contractionGO:0086003100.013
regulation of transporter activityGO:0032409500.013
actin cytoskeleton organizationGO:0030036730.013
response to carbohydrateGO:00097431830.013
nucleobase containing compound catabolic processGO:00346551520.013
regulation of secretion by cellGO:19035302080.013
Rat
gtp catabolic processGO:0006184710.013
cellular response to stressGO:00335542690.013
positive regulation of neuron differentiationGO:00456661260.013
regulation of protein modification processGO:00313991940.013
receptor internalizationGO:0031623140.012
regulation of small gtpase mediated signal transductionGO:0051056480.012
rna localizationGO:000640340.012
regulation of peptide hormone secretionGO:0090276800.012
Rat
response to metal ionGO:00100382530.012
Rat
cellular response to organonitrogen compoundGO:00714171970.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
negative regulation of calcium ion importGO:009028120.012
cellular response to endogenous stimulusGO:00714953770.012
mast cell migrationGO:009753140.012
endoplasmic reticulum membrane organizationGO:009015810.012
Yeast
regulation of heart contractionGO:0008016480.012
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711320.012
neuron neuron synaptic transmissionGO:0007270600.012
calcium ion transportGO:00068161310.012
purine ribonucleoside metabolic processGO:00461281680.012
regulation of apoptotic processGO:00429813350.012
response to ketoneGO:19016541820.012
regulation of axonogenesisGO:0050770370.012
regulation of peptidase activityGO:0052547550.012
organophosphate biosynthetic processGO:00904071430.012
negative regulation of synaptic transmissionGO:0050805290.012
regulation of hormone secretionGO:00468831060.012
Rat
regulation of cellular component sizeGO:0032535510.012
response to heatGO:0009408600.012
second messenger mediated signalingGO:0019932510.012
cellular response to growth factor stimulusGO:00713631620.012
cellular protein complex assemblyGO:0043623440.012
regulation of cell proliferationGO:00421273590.012
positive regulation of synaptic vesicle exocytosisGO:200030230.012
cellular component maintenanceGO:004395440.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
regulation of proteolysisGO:0030162660.012
regulation of purine nucleotide metabolic processGO:19005421150.012
negative regulation of metabolic processGO:00098923310.012
purine nucleoside catabolic processGO:00061521240.012
potassium ion transportGO:0006813970.012
cardiac conductionGO:006133720.012
negative regulation of locomotionGO:0040013410.012
synaptic transmission glutamatergicGO:0035249330.012
gtp metabolic processGO:0046039720.012
cellular response to nitrogen compoundGO:19016992100.012
negative regulation of molecular functionGO:00440921330.012
ethanolamine containing compound metabolic processGO:0042439140.012
negative regulation of programmed cell deathGO:00430691830.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
positive regulation of signalingGO:00230562700.012
glycerolipid metabolic processGO:0046486670.011
Yeast
regulation of reactive oxygen species biosynthetic processGO:190342650.011
action potentialGO:0001508540.011
purine nucleotide catabolic processGO:00061951360.011
heterocycle catabolic processGO:00467001670.011
ion homeostasisGO:00508012120.011
hormone transportGO:00099141210.011
Rat
single organism membrane fusionGO:0044801170.011
Rat
regulation of catabolic processGO:00098941130.011
positive regulation of serotonin secretionGO:001406410.011
regulation of dendrite developmentGO:0050773590.011
positive regulation of focal adhesion assemblyGO:005189420.011
cell type specific apoptotic processGO:00972851340.011
regulation of striated muscle contractionGO:0006942210.011
protein homooligomerizationGO:0051260910.011
neuron projection extensionGO:1990138260.011
respiratory gaseous exchangeGO:000758540.011
programmed cell deathGO:00125013920.011
negative regulation of neuron differentiationGO:0045665620.011
positive regulation of cell proliferationGO:00082842490.011
positive regulation of synaptic transmissionGO:0050806620.011
regulation of microtubule polymerization or depolymerizationGO:0031110120.011
positive regulation of hydrolase activityGO:0051345860.011
regulation of metal ion transportGO:00109591180.011
neuroblast differentiationGO:001401610.011
axon extensionGO:0048675260.011
positive regulation of phosphorylationGO:00423271770.011
response to phGO:0009268270.011
peptide secretionGO:0002790860.011
Rat
negative regulation of protein processingGO:0010955470.011
developmental growth involved in morphogenesisGO:0060560330.011
positive regulation of transferase activityGO:0051347810.011
regulation of protein maturationGO:1903317500.010
cellular response to mechanical stimulusGO:0071260480.010
multi organism reproductive processGO:00447032620.010
cellular ketone metabolic processGO:0042180510.010
purine ribonucleotide catabolic processGO:00091541360.010
positive regulation of protein phosphorylationGO:00019341350.010
olfactory learningGO:000835510.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
regulation of neuron apoptotic processGO:0043523830.010
behaviorGO:00076102050.010
insulin secretionGO:0030073690.010
Rat
reproductive structure developmentGO:00486081280.010
ovulation cycleGO:0042698670.010
dendritic spine morphogenesisGO:006099790.010
glycosyl compound metabolic processGO:19016571820.010
male gamete generationGO:0048232990.010
peptidyl amino acid modificationGO:00181931260.010
response to woundingGO:00096112540.010

Syt11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.052
disease of anatomical entityDOID:700.052
central nervous system diseaseDOID:33100.025
heart conduction diseaseDOID:1027300.015
familial atrial fibrillationDOID:005065000.015
cardiovascular system diseaseDOID:128700.015
substance dependenceDOID:997300.013
substance related disorderDOID:30300.013
disease of mental healthDOID:15000.013
neuropathyDOID:87000.012
neuromuscular diseaseDOID:44000.012