Rattus norvegicus

2 known processes

Man2b1

mannosidase, alpha, class 2B, member 1

(Aliases: MGC72561,Manb)

Man2b1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism catabolic processGO:00447122830.205
catabolic processGO:00090563510.199
cellular response to endogenous stimulusGO:00714953770.189
organonitrogen compound catabolic processGO:19015651790.175
organic substance catabolic processGO:19015753160.171
tissue developmentGO:00098882520.118
organic acid metabolic processGO:00060822920.117
cell morphogenesis involved in differentiationGO:00009041190.116
sulfur compound metabolic processGO:0006790700.110
carbohydrate derivative catabolic processGO:19011361470.107
oxoacid metabolic processGO:00434362900.095
regulation of molecular functionGO:00650093980.087
response to inorganic substanceGO:00100353770.084
inflammatory responseGO:00069541500.081
carbohydrate derivative metabolic processGO:19011353460.073
regulation of secretion by cellGO:19035302080.068
organelle organizationGO:00069962660.068
immune system developmentGO:0002520410.064
keratan sulfate metabolic processGO:004233910.062
cellular response to organonitrogen compoundGO:00714171970.060
cellular response to peptideGO:19016531330.057
oxidation reduction processGO:00551143040.057
ion homeostasisGO:00508012120.056
cellular response to hormone stimulusGO:00328702470.055
response to carbohydrateGO:00097431830.053
multicellular organism reproductionGO:00325042330.051
t cell tolerance inductionGO:000251730.049
cellular chemical homeostasisGO:00550822470.047
cellular response to nitrogen compoundGO:19016992100.047
dephosphorylationGO:0016311980.046
cellular amine metabolic processGO:0044106380.045
regulation of cellular component organizationGO:00511283680.045
cell cell signalingGO:00072673350.044
cellular catabolic processGO:00442482950.044
carboxylic acid metabolic processGO:00197522890.043
respiratory system developmentGO:0060541450.043
anatomical structure morphogenesisGO:00096532980.042
positive regulation of multicellular organismal processGO:00512403870.042
heart morphogenesisGO:000300730.041
regulation of body fluid levelsGO:0050878900.041
response to fatty acidGO:0070542650.040
cellular amino acid metabolic processGO:00065201070.040
regulation of system processGO:00440572080.039
lipid metabolic processGO:00066292830.039
head developmentGO:00603222470.039
wound healingGO:00420601220.038
cellular response to abiotic stimulusGO:0071214850.038
intracellular signal transductionGO:00355563140.036
regulation of hormone levelsGO:00108171870.036
sulfur compound catabolic processGO:004427330.036
monocarboxylic acid metabolic processGO:00327871520.036
cellular response to organic cyclic compoundGO:00714072020.036
positive regulation of response to stimulusGO:00485842850.036
nucleoside phosphate metabolic processGO:00067532830.035
amine metabolic processGO:0009308380.035
reproductive processGO:00224143720.035
nucleobase containing small molecule metabolic processGO:00550863160.035
single organism carbohydrate metabolic processGO:00447231180.035
cation homeostasisGO:00550801950.035
gland developmentGO:00487321550.035
chemical homeostasisGO:00488782920.034
response to metal ionGO:00100382530.034
response to monosaccharideGO:00342841590.034
regulation of organelle organizationGO:0033043800.034
positive regulation of cell differentiationGO:00455972170.034
protein phosphorylationGO:00064683450.034
nucleic acid templated transcriptionGO:00976593790.033
positive regulation of signalingGO:00230562700.033
hemopoiesisGO:0030097340.033
regulation of multicellular organismal developmentGO:20000263760.032
neuron differentiationGO:00301823680.032
secretionGO:00469033070.032
regulation of tolerance induction dependent upon immune responseGO:000265210.032
hematopoietic or lymphoid organ developmentGO:0048534360.031
regulation of cellular protein metabolic processGO:00322682670.031
negative regulation of natural killer cell mediated immunityGO:000271640.031
response to decreased oxygen levelsGO:00362932370.031
single organism reproductive processGO:00447022970.031
hematopoietic progenitor cell differentiationGO:000224420.031
sensory perceptionGO:00076001010.031
regulation of secretionGO:00510462240.031
renal system developmentGO:0072001670.030
synaptic transmissionGO:00072682350.030
cellular response to peptide hormone stimulusGO:00713751200.030
negative regulation of innate immune responseGO:004582440.030
multi organism reproductive processGO:00447032620.030
regulation of tolerance induction to nonself antigenGO:000265510.030
homeostatic processGO:00425923310.030
regulation of transcription from rna polymerase ii promoterGO:00063572340.030
response to woundingGO:00096112540.029
positive regulation of tolerance inductionGO:000264510.029
regulation of cell developmentGO:00602842630.029
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.029
organ morphogenesisGO:0009887750.029
ribonucleotide metabolic processGO:00092592310.029
regulation of signal transductionGO:00099663180.028
metal ion transportGO:00300012890.028
liver developmentGO:0001889900.028
regulation of kinase activityGO:00435491170.028
macromolecule catabolic processGO:0009057580.028
b cell differentiationGO:003018320.028
positive regulation of transportGO:00510502450.028
response to peptideGO:19016522920.027
axis specificationGO:000979840.027
cellular component movementGO:00069282480.027
positive regulation of tolerance induction dependent upon immune responseGO:000265410.027
lymphocyte activationGO:0046649430.026
regulation of cellular amino acid metabolic processGO:000652120.026
regulation of cell differentiationGO:00455953200.026
immune system processGO:00023762040.026
regulation of rna biosynthetic processGO:20011413810.026
ion transmembrane transportGO:00342203650.026
tube developmentGO:0035295890.026
organophosphate metabolic processGO:00196373700.026
secretion by cellGO:00329402480.025
response to extracellular stimulusGO:00099913800.025
sequestering of metal ionGO:005123890.025
cellular response to external stimulusGO:00714961180.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
gamete generationGO:00072761240.025
ossificationGO:0001503700.024
regulation of metal ion transportGO:00109591180.024
positive regulation of cellular biosynthetic processGO:00313282950.024
behaviorGO:00076102050.024
ribose phosphate metabolic processGO:00196932350.024
response to peptide hormoneGO:00434342780.024
activation of cysteine type endopeptidase activityGO:009720240.023
positive regulation of programmed cell deathGO:00430681570.023
cell motilityGO:00488702020.023
myeloid cell differentiationGO:0030099220.023
glycosyl compound metabolic processGO:19016571820.023
positive regulation of gene expressionGO:00106282440.023
response to hexoseGO:00097461440.022
single organism carbohydrate catabolic processGO:0044724400.022
leukocyte differentiationGO:0002521300.022
cellular ketone metabolic processGO:0042180510.022
positive regulation of cellular protein metabolic processGO:00322701670.022
signal transduction by phosphorylationGO:00230141440.022
lymphocyte proliferationGO:0046651290.022
memoryGO:0007613540.022
cellular response to lipidGO:00713962010.022
response to aluminum ionGO:0010044100.022
positive regulation of phosphate metabolic processGO:00459372620.022
embryonic pattern specificationGO:000988010.022
reproductionGO:00000032450.022
regulation of anatomical structure sizeGO:00900661350.022
apoptotic processGO:00069153810.022
response to acid chemicalGO:00011012220.021
reproductive system developmentGO:00614581280.021
transcription from rna polymerase ii promoterGO:00063662520.021
sequestering of calcium ionGO:005120880.021
positive regulation of neuron projection developmentGO:0010976990.021
regulation of intracellular transportGO:0032386650.021
purine containing compound metabolic processGO:00725212530.021
regulation of cell projection organizationGO:00313441750.021
enzyme linked receptor protein signaling pathwayGO:00071671160.021
regulation of ion homeostasisGO:2000021630.020
response to radiationGO:00093141370.020
response to glucoseGO:00097491360.020
programmed cell deathGO:00125013920.020
leukocyte mediated immunityGO:0002443280.020
cellular response to growth factor stimulusGO:00713631620.020
chromosome organizationGO:0051276360.020
response to oxygen levelsGO:00704822650.020
divalent inorganic cation homeostasisGO:00725071650.020
single organism behaviorGO:00447081300.020
positive regulation of cellular component organizationGO:00511302000.020
sexual reproductionGO:00199531480.020
regulation of cellular component movementGO:00512701500.019
nitrogen compound transportGO:00717052290.019
purine ribonucleotide metabolic processGO:00091502270.019
cell projection organizationGO:00300303020.019
negative regulation of immune system processGO:0002683390.019
regulation of neurogenesisGO:00507672470.019
positive regulation of biosynthetic processGO:00098913190.019
regulation of protein transportGO:0051223680.019
rna metabolic processGO:00160704060.019
cell adhesionGO:00071551100.019
positive regulation of catalytic activityGO:00430851840.019
regulation of phosphorus metabolic processGO:00511743490.019
multicellular organismal reproductive processGO:00486092330.019
developmental process involved in reproductionGO:00030061590.019
hormone secretionGO:00468791150.019
limb morphogenesisGO:003510840.019
regulation of blood pressureGO:0008217830.019
single organism biosynthetic processGO:00447113420.019
negative regulation of transportGO:00510511360.018
regulation of response to external stimulusGO:00321011060.018
regulation of protein metabolic processGO:00512462890.018
nucleotide metabolic processGO:00091172790.018
regulation of cellular localizationGO:00603412630.018
metal ion homeostasisGO:00550651860.018
regulation of smooth muscle cell proliferationGO:0048660750.018
immunoglobulin mediated immune responseGO:001606440.018
response to nutrient levelsGO:00316673700.018
regulation of catalytic activityGO:00507903040.018
calcium ion homeostasisGO:00550741620.018
positive regulation of protein metabolic processGO:00512471780.018
cellular response to oxygen containing compoundGO:19017013860.018
cell migrationGO:00164771970.018
positive regulation of cell communicationGO:00106472710.018
nucleoside phosphate biosynthetic processGO:19012931020.018
rna biosynthetic processGO:00327743800.017
protein localizationGO:00081041910.017
receptor mediated endocytosisGO:0006898420.017
aromatic compound catabolic processGO:00194391680.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.017
epithelial cell differentiationGO:0030855710.017
regulation of homeostatic processGO:00328441010.017
mapk cascadeGO:00001651400.017
neuron projection developmentGO:00311752730.017
positive regulation of cytokine productionGO:0001819420.017
developmental growthGO:00485891000.017
platelet aggregationGO:007052740.017
response to organophosphorusGO:00466831020.017
lung developmentGO:0030324430.017
proteolysisGO:00065081750.017
positive regulation of nucleobase containing compound metabolic processGO:00459353190.017
regulation of cellular amine metabolic processGO:003323880.017
cellular response to iron ion starvationGO:001010610.017
nucleotide biosynthetic processGO:0009165980.017
response to hypoxiaGO:00016662310.017
carbohydrate metabolic processGO:00059751300.017
transmembrane transportGO:00550854120.016
macromolecule localizationGO:00330362520.016
positive regulation of cellular amine metabolic processGO:003324030.016
response to ketoneGO:19016541820.016
calcium ion transportGO:00068161310.016
cellular metal ion homeostasisGO:00068751720.016
positive regulation of nitrogen compound metabolic processGO:00511733340.016
positive regulation of cell developmentGO:00107201760.016
positive regulation of protein kinase activityGO:0045860730.016
cell part morphogenesisGO:00329901230.016
cellular ion homeostasisGO:00068731840.016
response to oxidative stressGO:00069791860.016
calcium ion transport into cytosolGO:0060402380.016
localization of cellGO:00516742020.016
neuron developmentGO:00486662860.016
regulation of apoptotic processGO:00429813350.016
response to insulinGO:00328681330.016
nucleotide catabolic processGO:00091661390.016
positive regulation of kinase activityGO:0033674770.016
regulation of neuron projection developmentGO:00109751610.016
sensory perception of painGO:0019233730.015
cellular response to ketoneGO:1901655510.015
tissue morphogenesisGO:0048729220.015
regulation of nucleotide metabolic processGO:00061401170.015
transcription dna templatedGO:00063513770.015
cation transportGO:00068123820.015
regulation of cell morphogenesis involved in differentiationGO:0010769720.015
salivary gland developmentGO:000743130.015
b cell mediated immunityGO:001972440.015
positive regulation of molecular functionGO:00440932300.015
tolerance induction dependent upon immune responseGO:000246120.015
cation transmembrane transportGO:00986552630.015
dna metabolic processGO:0006259960.015
regulation of protein modification processGO:00313991940.015
positive regulation of secretion by cellGO:19035321280.015
positive regulation of developmental processGO:00510942830.015
response to mechanical stimulusGO:00096121340.015
organophosphate catabolic processGO:00464341480.015
tissue regenerationGO:0042246360.015
synapse organizationGO:0050808460.015
positive regulation of transferase activityGO:0051347810.015
anion transportGO:00068201780.015
regulation of hormone secretionGO:00468831060.015
positive regulation of rna biosynthetic processGO:19026801970.015
cellular homeostasisGO:00197252520.015
ovulation cycleGO:0042698670.015
organic hydroxy compound metabolic processGO:19016151150.014
regulation of neuron differentiationGO:00456642080.014
regulation of immune system processGO:00026821230.014
defense responseGO:00069521940.014
regulation of cellular ketone metabolic processGO:0010565270.014
tolerance induction to nonself antigenGO:000246220.014
g protein coupled receptor signaling pathwayGO:00071862420.014
cell activationGO:0001775970.014
regulation of protein kinase activityGO:00458591050.014
embryonic skeletal system developmentGO:004870630.014
positive regulation of cell projection organizationGO:00313461110.014
salivary gland morphogenesisGO:000743510.014
peptidyl amino acid modificationGO:00181931260.014
positive regulation of locomotionGO:00400171020.014
regulation of nervous system developmentGO:00519602640.014
positive regulation of transcription dna templatedGO:00458931970.014
positive regulation of cell migrationGO:0030335960.014
detection of stimulusGO:0051606240.014
response to purine containing compoundGO:00140741260.014
negative regulation of programmed cell deathGO:00430691830.014
positive regulation of nervous system developmentGO:00519621780.014
cytoplasmic transportGO:00164821150.014
small gtpase mediated signal transductionGO:0007264360.014
cellular lipid metabolic processGO:00442552080.014
negative regulation of cell deathGO:00605482290.014
negative regulation of signalingGO:00230571570.014
epithelium developmentGO:0060429960.014
macromolecular complex subunit organizationGO:00439333390.014
respiratory tube developmentGO:0030323430.014
vasculogenesisGO:000157030.014
cellular cation homeostasisGO:00300031800.013
hexose metabolic processGO:0019318580.013
cell cycle checkpointGO:000007520.013
carbohydrate derivative biosynthetic processGO:19011371240.013
regulation of cell motilityGO:20001451310.013
response to hydrogen peroxideGO:0042542890.013
appendage morphogenesisGO:003510740.013
protein transportGO:00150311320.013
brain developmentGO:00074202470.013
smooth muscle cell migrationGO:0014909360.013
neurological system processGO:00508772190.013
regulation of phosphate metabolic processGO:00192203490.013
cytosolic calcium ion transportGO:0060401390.013
spermatogenesisGO:0007283990.013
positive regulation of phosphorus metabolic processGO:00105622620.013
erbb signaling pathwayGO:0038127230.013
regulation of b cell mediated immunityGO:000271220.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
cell morphogenesisGO:00009021420.013
reproductive structure developmentGO:00486081280.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
embryonic skeletal system morphogenesisGO:004870430.013
regulation of tube sizeGO:0035150890.013
regulation of purine nucleotide metabolic processGO:19005421150.012
regulation of ion transportGO:00432692450.012
positive regulation of hydrolase activityGO:0051345860.012
positive regulation of dendrite developmentGO:1900006350.012
central nervous system developmentGO:00074173110.012
cerebral cortex cell migrationGO:002179540.012
positive regulation of protein modification processGO:00314011420.012
blood circulationGO:00080151830.012
cellular nitrogen compound catabolic processGO:00442701630.012
regulation of hydrolase activityGO:00513361430.012
negative regulation of secretion by cellGO:1903531720.012
regulation of phosphorylationGO:00423252480.012
positive regulation of rna metabolic processGO:00512542030.012
response to sterolGO:0036314130.012
artery developmentGO:006084030.012
regulation of cell cycleGO:0051726730.012
learning or memoryGO:0007611900.012
development of primary sexual characteristicsGO:00451371070.012
hormone mediated signaling pathwayGO:0009755230.012
regulation of muscle system processGO:0090257790.012
negative regulation of cell proliferationGO:00082851190.012
positive regulation of intracellular signal transductionGO:19025331380.012
positive regulation of epidermis developmentGO:004568410.012
cell projection morphogenesisGO:00488581230.012
response to starvationGO:0042594590.012
response to molecule of bacterial originGO:00022371940.011
vesicle mediated transportGO:00161921810.011
organic anion transportGO:00157111320.011
positive regulation of neurogenesisGO:00507691650.011
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.011
regulation of metanephros developmentGO:007221540.011
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.011
cellular component morphogenesisGO:00329891550.011
regulation of mapk cascadeGO:00434081160.011
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.011
positive regulation of protein serine threonine kinase activityGO:0071902520.011
organophosphate biosynthetic processGO:00904071430.011
purine ribonucleoside monophosphate metabolic processGO:0009167840.011
inorganic ion transmembrane transportGO:00986602290.011
hemostasisGO:0007599260.011
multicellular organism growthGO:003526410.011
regulation of immune responseGO:0050776550.011
phospholipid metabolic processGO:0006644610.011
positive regulation of cell deathGO:00109421840.011
endocytosisGO:0006897840.011
ribonucleoside monophosphate metabolic processGO:0009161880.011
positive regulation of cell proliferationGO:00082842490.011
gtp metabolic processGO:0046039720.011
cellular response to insulin stimulusGO:0032869810.011
synaptic growth at neuromuscular junctionGO:005112410.011
nucleobase containing compound catabolic processGO:00346551520.011
myeloid leukocyte differentiationGO:0002573200.011
cellular response to corticosteroid stimulusGO:0071384690.011
positive regulation of protein transportGO:0051222410.011
anterior posterior pattern specificationGO:000995210.011
response to transition metal nanoparticleGO:19902671220.011
sex differentiationGO:00075481130.011
ribonucleotide biosynthetic processGO:0009260850.011
feeding behaviorGO:0007631530.011
organonitrogen compound biosynthetic processGO:19015661670.011
prostate gland morphogenesisGO:006051220.011
positive regulation of protein phosphorylationGO:00019341350.011
cyclic purine nucleotide metabolic processGO:0052652620.011
neuron fate commitmentGO:004866340.011
positive regulation of secretionGO:00510471400.011
positive regulation of t cell mediated cytotoxicityGO:000191640.011
divalent inorganic cation transportGO:00725111340.011
embryonic cranial skeleton morphogenesisGO:004870120.011
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.010
smooth muscle cell proliferationGO:0048659770.010
inner ear receptor cell differentiationGO:006011320.010
lymphocyte mediated immunityGO:0002449140.010
cellular lipid catabolic processGO:0044242370.010
hormone metabolic processGO:0042445690.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.010
positive regulation of tolerance induction to nonself antigenGO:000265710.010
embryonic limb morphogenesisGO:003032640.010
circulatory system processGO:00030131830.010
regulation of immune effector processGO:0002697320.010
hepaticobiliary system developmentGO:0061008900.010
negative regulation of ion transportGO:0043271510.010
dna integrity checkpointGO:003157020.010
positive regulation of cellular component movementGO:00512721020.010
hormone transportGO:00099141210.010
mesoderm developmentGO:000749820.010
sensory perception of bitter tasteGO:005091340.010
endoplasmic reticulum organizationGO:000702910.010
synaptic vesicle endocytosisGO:004848840.010
regulation of blood vessel sizeGO:0050880890.010
positive regulation of cell growthGO:0030307440.010
positive regulation of endothelial cell migrationGO:001059540.010
negative regulation of secretionGO:0051048820.010

Man2b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.039
brain diseaseDOID:93600.039
cerebral degenerationDOID:144300.039
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.039
inherited metabolic disorderDOID:65500.032
Human
disease of metabolismDOID:001466700.032
Human
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013
sensory system diseaseDOID:005015500.013
connective tissue diseaseDOID:6500.011
musculoskeletal system diseaseDOID:1700.011
bone diseaseDOID:008000100.011
cardiovascular system diseaseDOID:128700.011
vascular diseaseDOID:17800.011