Rattus norvegicus

29 known processes

Ireb2

iron responsive element binding protein 2

(Aliases: MGC93423,Irp2)

Ireb2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular localizationGO:00603412630.293
protein complex subunit organizationGO:00718223020.264
transcription dna templatedGO:00063513770.233
positive regulation of transportGO:00510502450.217
organ morphogenesisGO:0009887750.212
cellular response to stressGO:00335542690.200
nucleic acid templated transcriptionGO:00976593790.199
protein complex biogenesisGO:00702712630.196
protein complex assemblyGO:00064612630.191
positive regulation of macromolecule biosynthetic processGO:00105572470.171
immune system processGO:00023762040.156
rna biosynthetic processGO:00327743800.154
regulation of transcription dna templatedGO:00063553740.144
positive regulation of rna biosynthetic processGO:19026801970.144
carbohydrate derivative metabolic processGO:19011353460.142
organic substance catabolic processGO:19015753160.142
macromolecular complex assemblyGO:00650032730.136
positive regulation of catalytic activityGO:00430851840.134
protein homooligomerizationGO:0051260910.132
response to toxic substanceGO:00096361330.131
cellular response to oxygen containing compoundGO:19017013860.120
regulation of molecular functionGO:00650093980.120
apoptotic processGO:00069153810.119
response to other organismGO:00517072200.118
macromolecular complex subunit organizationGO:00439333390.117
regulation of transcription from rna polymerase ii promoterGO:00063572340.116
protein phosphorylationGO:00064683450.115
rna metabolic processGO:00160704060.110
positive regulation of biosynthetic processGO:00098913190.107
response to cytokineGO:00340972150.107
neurological system processGO:00508772190.106
wnt signaling pathway planar cell polarity pathwayGO:006007120.106
neural crest cell developmentGO:001403220.105
programmed cell deathGO:00125013920.104
cellular component biogenesisGO:00440853680.102
cellular component assemblyGO:00226073600.097
positive regulation of response to stimulusGO:00485842850.097
regulation of protein oligomerizationGO:003245920.096
cellular catabolic processGO:00442482950.096
mesoderm developmentGO:000749820.095
purine ribonucleotide catabolic processGO:00091541360.095
positive regulation of cellular biosynthetic processGO:00313282950.094
protein o linked glycosylationGO:000649320.094
immune responseGO:00069551040.094
catabolic processGO:00090563510.093
positive regulation of nucleic acid templated transcriptionGO:19035081970.093
cellular response to growth factor stimulusGO:00713631620.090
response to decreased oxygen levelsGO:00362932370.090
apoptotic signaling pathwayGO:0097190270.089
cation transportGO:00068123820.089
cellular ion homeostasisGO:00068731840.088
Rat
regulation of cell cycleGO:0051726730.087
neuron apoptotic processGO:0051402880.087
positive regulation of interleukin 1 secretionGO:005071630.087
cellular response to lipidGO:00713962010.084
homeostatic processGO:00425923310.084
Rat
regulation of secretionGO:00510462240.084
carbohydrate metabolic processGO:00059751300.082
tissue developmentGO:00098882520.082
negative regulation of tor signalingGO:003200720.081
intracellular signal transductionGO:00355563140.079
central nervous system developmentGO:00074173110.078
protein oligomerizationGO:00512591910.077
transcription from rna polymerase ii promoterGO:00063662520.077
cellular response to molecule of bacterial originGO:0071219560.076
regulation of catalytic activityGO:00507903040.075
activation of jak2 kinase activityGO:004297720.074
regulation of nucleic acid templated transcriptionGO:19035063800.074
digestive tract developmentGO:0048565390.074
Fly
regulation of establishment of protein localizationGO:0070201690.073
response to monosaccharideGO:00342841590.072
protein transportGO:00150311320.072
positive regulation of cell proliferationGO:00082842490.072
reproductive processGO:00224143720.071
positive regulation of molecular functionGO:00440932300.071
response to molecule of bacterial originGO:00022371940.069
response to hexoseGO:00097461440.069
positive regulation of gene expressionGO:00106282440.069
regulation of vesicle mediated transportGO:0060627810.069
response to alkaloidGO:00432791320.068
regulation of response to stressGO:00801341260.068
locomotionGO:00400112370.068
nucleoside triphosphate metabolic processGO:00091411440.066
purine ribonucleotide metabolic processGO:00091502270.066
positive regulation of rna metabolic processGO:00512542030.066
regulation of apoptotic processGO:00429813350.066
proteolysisGO:00065081750.065
positive regulation of secretion by cellGO:19035321280.065
nucleoside metabolic processGO:00091161790.065
positive regulation of nitrogen compound metabolic processGO:00511733340.065
defense responseGO:00069521940.064
cellular response to endogenous stimulusGO:00714953770.062
regulation of cellular protein metabolic processGO:00322682670.061
positive regulation of protein metabolic processGO:00512471780.060
head developmentGO:00603222470.060
tube developmentGO:0035295890.059
Fly
carbohydrate derivative biosynthetic processGO:19011371240.058
regulation of protein phosphorylationGO:00019321830.058
response to glucocorticoidGO:00513842230.057
response to purine containing compoundGO:00140741260.057
reproductive system developmentGO:00614581280.057
cell cell signalingGO:00072673350.057
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.056
receptor localization to synapseGO:009712020.055
growthGO:00400071650.054
negative regulation of response to stimulusGO:00485851550.054
response to lipopolysaccharideGO:00324961910.054
regulation of rna biosynthetic processGO:20011413810.054
single organism catabolic processGO:00447122830.053
ion homeostasisGO:00508012120.053
Rat
positive regulation of apoptotic processGO:00430651540.053
response to acid chemicalGO:00011012220.053
positive regulation of multicellular organismal processGO:00512403870.052
response to woundingGO:00096112540.052
gastrulationGO:000736920.050
Fly
nucleobase containing small molecule metabolic processGO:00550863160.050
protein prenylationGO:001834240.050
glycoprotein biosynthetic processGO:0009101190.049
nucleoside phosphate catabolic processGO:19012921400.049
response to glucoseGO:00097491360.049
regulation of neuron apoptotic processGO:0043523830.049
cellular response to peptide hormone stimulusGO:00713751200.048
regulation of hydrolase activityGO:00513361430.048
positive regulation of cell deathGO:00109421840.048
positive regulation of cellular component organizationGO:00511302000.048
learning or memoryGO:0007611900.047
neuron deathGO:00709971270.047
regulation of protein transportGO:0051223680.047
regulation of intracellular signal transductionGO:19025312180.047
regulation of cell developmentGO:00602842630.046
response to tumor necrosis factorGO:0034612560.046
glycosyl compound metabolic processGO:19016571820.046
regulation of programmed cell deathGO:00430673410.045
cognitionGO:0050890920.044
metal ion homeostasisGO:00550651860.044
Rat
cellular response to organonitrogen compoundGO:00714171970.044
response to external biotic stimulusGO:00432072210.044
macromolecule glycosylationGO:0043413140.043
regulation of cell proliferationGO:00421273590.043
response to metal ionGO:00100382530.042
nucleotide metabolic processGO:00091172790.042
regulation of cellular component organizationGO:00511283680.042
gland developmentGO:00487321550.042
regulation of rna metabolic processGO:00512523910.042
tube formationGO:003514830.042
positive regulation of transcription dna templatedGO:00458931970.041
secretionGO:00469033070.041
regulation of phosphorylationGO:00423252480.041
response to peptideGO:19016522920.041
multicellular organism reproductionGO:00325042330.041
regulation of protein metabolic processGO:00512462890.041
wound healingGO:00420601220.041
nucleotide catabolic processGO:00091661390.041
purine containing compound metabolic processGO:00725212530.041
agingGO:00075682410.040
divalent metal ion transportGO:00708381320.040
cellular response to lipopolysaccharideGO:0071222550.040
regulation of cellular component movementGO:00512701500.040
negative regulation of developmental processGO:00510931250.040
regulation of protein localizationGO:0032880810.040
anatomical structure formation involved in morphogenesisGO:0048646830.040
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353190.040
regulation of cell differentiationGO:00455953200.039
regulation of nervous system developmentGO:00519602640.039
response to oxidative stressGO:00069791860.039
organonitrogen compound catabolic processGO:19015651790.039
response to ethanolGO:00454711620.039
purine ribonucleoside metabolic processGO:00461281680.039
ribonucleotide metabolic processGO:00092592310.039
positive regulation of signalingGO:00230562700.039
negative regulation of signalingGO:00230571570.039
single organism reproductive processGO:00447022970.039
response to growth factorGO:00708481890.039
organonitrogen compound biosynthetic processGO:19015661670.038
negative regulation of macromolecule metabolic processGO:00106052600.038
negative regulation of apoptotic processGO:00430661810.038
purine containing compound catabolic processGO:00725231380.038
intracellular transportGO:00469071850.038
regulation of multicellular organismal developmentGO:20000263760.037
response to oxygen levelsGO:00704822650.037
nucleoside catabolic processGO:00091641260.037
purine nucleotide metabolic processGO:00061632290.037
regulation of growthGO:00400081050.037
cellular protein localizationGO:00346131220.037
oxoacid metabolic processGO:00434362900.036
regenerationGO:00310991630.036
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.036
negative regulation of transportGO:00510511360.036
positive regulation of programmed cell deathGO:00430681570.036
response to radiationGO:00093141370.036
regulation of phosphate metabolic processGO:00192203490.036
neural crest cell migrationGO:000175510.036
muscle cell differentiationGO:0042692520.036
localization of cellGO:00516742020.036
cellular response to organic cyclic compoundGO:00714072020.035
purine nucleoside metabolic processGO:00422781690.035
ribose phosphate metabolic processGO:00196932350.035
regulation of smooth muscle cell proliferationGO:0048660750.035
digestive system developmentGO:0055123410.035
Fly
circadian rhythmGO:0007623880.034
regulation of cytokine productionGO:0001817560.034
brain developmentGO:00074202470.034
cell motilityGO:00488702020.034
negative regulation of multicellular organismal processGO:00512412030.034
cellular response to acid chemicalGO:0071229750.034
response to transition metal nanoparticleGO:19902671220.034
metal ion transportGO:00300012890.033
purine nucleoside triphosphate metabolic processGO:00091441410.033
mesodermal cell differentiationGO:004833310.033
nucleoside triphosphate catabolic processGO:00091431230.033
response to inorganic substanceGO:00100353770.033
ribonucleotide catabolic processGO:00092611360.033
positive regulation of immune system processGO:0002684900.032
single organism biosynthetic processGO:00447113420.032
purine ribonucleoside triphosphate metabolic processGO:00092051400.032
negative regulation of cell deathGO:00605482290.032
macromolecule localizationGO:00330362520.032
cellular amino acid metabolic processGO:00065201070.031
response to carbohydrateGO:00097431830.031
organelle organizationGO:00069962660.031
neuron differentiationGO:00301823680.031
cellular response to external stimulusGO:00714961180.030
regulation of hormone levelsGO:00108171870.030
negative regulation of metabolic processGO:00098923310.030
positive regulation of cell motilityGO:2000147970.030
vasculogenesisGO:000157030.030
organ regenerationGO:00311001010.030
cellular chemical homeostasisGO:00550822470.030
Rat
divalent inorganic cation homeostasisGO:00725071650.029
regulation of locomotionGO:00400121480.029
reproductionGO:00000032450.029
positive regulation of cell communicationGO:00106472710.029
ribonucleoside catabolic processGO:00424541260.029
negative regulation of cell cycle phase transitionGO:190198840.029
cell substrate adhesionGO:0031589290.029
regulation of cell migrationGO:00303341280.029
negative regulation of signal transductionGO:0009968830.028
organic acid metabolic processGO:00060822920.028
cellular ketone metabolic processGO:0042180510.028
synaptic growth at neuromuscular junctionGO:005112410.028
regulation of protein modification processGO:00313991940.028
reproductive structure developmentGO:00486081280.028
actin filament based processGO:0030029860.028
organic cyclic compound catabolic processGO:19013611750.028
cellular response to drugGO:0035690300.028
epithelium developmentGO:0060429960.028
single organism organelle organizationGO:19025891800.027
response to estrogenGO:00436272320.027
cell migrationGO:00164771970.027
response to nicotineGO:0035094510.027
negative regulation of programmed cell deathGO:00430691830.027
response to peptide hormoneGO:00434342780.027
heterocycle catabolic processGO:00467001670.027
negative regulation of cell proliferationGO:00082851190.027
guanosine containing compound metabolic processGO:1901068740.027
protein autophosphorylationGO:0046777660.027
positive regulation of developmental processGO:00510942830.027
organophosphate catabolic processGO:00464341480.027
forebrain developmentGO:0030900980.027
glycoprotein metabolic processGO:0009100240.027
regulation of phosphorus metabolic processGO:00511743490.026
response to corticosteroidGO:00319602350.026
regulation of stress activated protein kinase signaling cascadeGO:0070302230.026
programmed necrotic cell deathGO:009730020.026
sensory organ developmentGO:0007423740.026
formation of primary germ layerGO:000170410.026
multicellular organismal reproductive processGO:00486092330.026
positive regulation of cellular protein metabolic processGO:00322701670.026
small gtpase mediated signal transductionGO:0007264360.026
protein heterooligomerizationGO:0051291890.025
sexual reproductionGO:00199531480.025
cellular component movementGO:00069282480.025
regulation of immune system processGO:00026821230.025
multi organism reproductive processGO:00447032620.025
developmental process involved in reproductionGO:00030061590.025
negative regulation of protein phosphorylationGO:0001933440.025
mesoderm morphogenesisGO:004833210.025
monocarboxylic acid metabolic processGO:00327871520.025
regulation of wound healingGO:0061041140.024
kidney developmentGO:0001822670.024
cell type specific apoptotic processGO:00972851340.024
purine nucleoside triphosphate catabolic processGO:00091461220.024
regulation of secretion by cellGO:19035302080.024
embryonic epithelial tube formationGO:000183830.024
protein maturationGO:0051604680.024
neural tube formationGO:000184110.023
positive regulation of interleukin 2 productionGO:003274310.023
response to ionizing radiationGO:0010212590.023
negative regulation of neuron deathGO:1901215690.023
mitotic cell cycleGO:0000278490.023
positive regulation of cytokine productionGO:0001819420.023
protein ubiquitinationGO:0016567280.023
acute inflammatory response to non antigenic stimulusGO:000252520.023
purine nucleoside catabolic processGO:00061521240.023
response to bacteriumGO:00096172000.023
multi multicellular organism processGO:00447061380.023
mitotic spindle organizationGO:000705220.023
glycosyl compound catabolic processGO:19016581260.023
memoryGO:0007613540.023
organophosphate metabolic processGO:00196373700.022
purine ribonucleoside catabolic processGO:00461301240.022
response to biotic stimulusGO:00096072260.022
ribonucleoside triphosphate catabolic processGO:00092031220.022
chemical homeostasisGO:00488782920.022
Rat
blood vessel morphogenesisGO:0048514580.022
single organism carbohydrate metabolic processGO:00447231180.022
nucleoside monophosphate metabolic processGO:0009123930.022
ossificationGO:0001503700.021
purine nucleotide catabolic processGO:00061951360.021
divalent inorganic cation transportGO:00725111340.021
carboxylic acid metabolic processGO:00197522890.021
cytokine productionGO:0001816610.021
response to campGO:0051591910.021
positive regulation of secretionGO:00510471400.021
regulation of retinal cell programmed cell deathGO:004666810.020
respiratory system developmentGO:0060541450.020
single organism intracellular transportGO:19025821660.020
negative regulation of cell communicationGO:00106481580.020
regulation of proteolysisGO:0030162660.020
muscle structure developmentGO:0061061870.020
positive regulation of protein transportGO:0051222410.020
response to reactive oxygen speciesGO:00003021200.020
nucleoside phosphate metabolic processGO:00067532830.020
negative regulation of cellular metabolic processGO:00313242810.020
epithelial cell proliferationGO:0050673540.020
regulation of system processGO:00440572080.020
neural crest cell differentiationGO:001403320.020
cellular metal ion homeostasisGO:00068751720.019
Rat
cellular macromolecule localizationGO:00707271220.019
positive regulation of protein phosphorylationGO:00019341350.019
regulation of organelle organizationGO:0033043800.019
signal releaseGO:00230611450.019
cellular nitrogen compound catabolic processGO:00442701630.019
nucleobase containing compound catabolic processGO:00346551520.019
gtp metabolic processGO:0046039720.019
regulation of signal transductionGO:00099663180.019
carbohydrate derivative catabolic processGO:19011361470.019
spindle organizationGO:000705120.019
cell morphogenesisGO:00009021420.019
positive regulation of peptide hormone secretionGO:0090277500.019
regulation of bmp signaling pathwayGO:003051020.019
ribonucleoside metabolic processGO:00091191740.018
cellular response to corticosteroid stimulusGO:0071384690.018
purine ribonucleoside triphosphate catabolic processGO:00092071220.018
cellular cation homeostasisGO:00300031800.018
Rat
response to nutrient levelsGO:00316673700.018
negative regulation of molecular functionGO:00440921330.018
positive regulation of cell developmentGO:00107201760.018
potassium ion transportGO:0006813970.018
establishment of protein localization to organelleGO:0072594440.018
establishment of protein localizationGO:00451841410.018
response to organophosphorusGO:00466831020.018
anterior posterior pattern specificationGO:000995210.018
regulation of homeostatic processGO:00328441010.018
gonad developmentGO:00084061040.018
wnt signaling pathwayGO:0016055170.017
regulation of anatomical structure sizeGO:00900661350.017
axis specificationGO:000979840.017
carbohydrate homeostasisGO:0033500750.017
cellular homeostasisGO:00197252520.017
Rat
activation of mapkkk activityGO:000018510.017
regulation of cellular amine metabolic processGO:003323880.017
connective tissue developmentGO:0061448330.017
embryo developmentGO:0009790490.017
Fly
response to hypoxiaGO:00016662310.017
negative regulation of catalytic activityGO:00430861030.017
hematopoietic or lymphoid organ developmentGO:0048534360.017
renal system developmentGO:0072001670.017
epithelial tube formationGO:007217530.017
cellular amine metabolic processGO:0044106380.017
erythrocyte homeostasisGO:003410120.017
regulation of hormone secretionGO:00468831060.017
calcium ion transportGO:00068161310.017
regulation of neuron deathGO:19012141150.017
atp metabolic processGO:0046034720.017
gamete generationGO:00072761240.017
regulation of cell motilityGO:20001451310.017
aromatic compound catabolic processGO:00194391680.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
negative regulation of mitotic cell cycle phase transitionGO:190199130.017
bmp signaling pathwayGO:003050940.017
camera type eye developmentGO:0043010480.017
regulation of establishment of planar polarityGO:009017520.016
signal transduction by phosphorylationGO:00230141440.016
biological adhesionGO:00226101100.016
circulatory system processGO:00030131830.016
regulation of wnt signaling pathwayGO:003011180.016
peristalsisGO:003043220.016
regulation of kinase activityGO:00435491170.016
positive regulation of neuron deathGO:1901216430.016
regulation of ion transportGO:00432692450.016
inflammatory responseGO:00069541500.016
protein localizationGO:00081041910.016
regulation of peptide secretionGO:0002791820.016
regulation of centrosome cycleGO:004660510.016
t cell migrationGO:007267820.016
protein processingGO:0016485680.016
cell projection organizationGO:00300303020.016
neuron projection developmentGO:00311752730.016
skeletal system developmentGO:0001501410.016
cell adhesionGO:00071551100.016
telencephalon developmentGO:0021537620.016
mitochondrion organizationGO:0007005350.015
positive regulation of peptide secretionGO:0002793520.015
rhythmic processGO:00485111560.015
ameboidal type cell migrationGO:0001667260.015
cellular calcium ion homeostasisGO:00068741600.015
protein geranylgeranylationGO:001834440.015
smooth muscle cell proliferationGO:0048659770.015
regulation of peptidase activityGO:0052547550.015
mapk cascadeGO:00001651400.015
response to hydrogen peroxideGO:0042542890.015
positive regulation of hydrolase activityGO:0051345860.015
cytoplasmic transportGO:00164821150.015
cell cycleGO:00070491010.015
behaviorGO:00076102050.015
cellular response to peptideGO:19016531330.015
positive regulation of neuron apoptotic processGO:0043525330.015
cellular protein complex assemblyGO:0043623440.015
cellular response to carbohydrate stimulusGO:0071322720.015
single organismal cell cell adhesionGO:0016337420.015
regulation of apoptotic signaling pathwayGO:2001233130.015
eye developmentGO:0001654500.014
protein modification by small protein conjugationGO:0032446310.014
guanosine containing compound catabolic processGO:1901069710.014
cellular response to nitrogen compoundGO:19016992100.014
positive regulation of cell differentiationGO:00455972170.014
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.014
cation homeostasisGO:00550801950.014
Rat
regulation of neurogenesisGO:00507672470.014
negative regulation of cardiac muscle cell proliferationGO:006004420.014
positive regulation of release of cytochrome c from mitochondriaGO:009020030.014
cellular response to biotic stimulusGO:0071216590.014
cell cycle checkpointGO:000007520.014
negative regulation of phosphorus metabolic processGO:0010563800.014
positive regulation of growthGO:0045927550.014
negative regulation of cellular protein metabolic processGO:00322691060.014
positive regulation of mitochondrion organizationGO:001082240.014
glucose homeostasisGO:0042593750.014
cell growthGO:00160491040.014
proteolysis involved in cellular protein catabolic processGO:0051603190.014
response to ketoneGO:19016541820.014
cytoskeleton organizationGO:00070101110.014
negative regulation of protein maturationGO:1903318470.013
immune system developmentGO:0002520410.013
positive regulation of protein localization to nucleusGO:1900182150.013
erythrocyte differentiationGO:003021810.013
stress activated mapk cascadeGO:0051403350.013
epithelial cell differentiationGO:0030855710.013
amide transportGO:00428861050.013
negative regulation of transcription dna templatedGO:00458921160.013
syncytium formation by plasma membrane fusionGO:000076830.013
urogenital system developmentGO:0001655780.013
endocardial cushion developmentGO:000319710.013
positive regulation of calcium ion transportGO:0051928360.013
mammary gland developmentGO:0030879380.013
amine metabolic processGO:0009308380.013
single organism membrane organizationGO:0044802740.013
nucleotide biosynthetic processGO:0009165980.013
nucleoside monophosphate catabolic processGO:0009125560.013
blood vessel developmentGO:0001568690.013
negative regulation of intracellular signal transductionGO:1902532380.013
cellular response to oxidative stressGO:0034599760.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
protein glycosylationGO:0006486140.013
morphogenesis of an epitheliumGO:0002009200.013
regulation of blood circulationGO:19035221100.013
cell junction assemblyGO:0034329180.013
protein targetingGO:0006605610.013
activation of protein kinase activityGO:0032147470.012
regulation of endocytosisGO:0030100420.012
regulation of peptide transportGO:0090087870.012
positive regulation of homeostatic processGO:0032846490.012
cell cycle processGO:0022402570.012
cellular response to hexose stimulusGO:0071331650.012
regulation of metal ion transportGO:00109591180.012
regulation of mapk cascadeGO:00434081160.012
positive regulation of cytosolic calcium ion concentrationGO:00072041220.012
purine nucleotide biosynthetic processGO:0006164830.012
regulation of cellular ketone metabolic processGO:0010565270.012
response to extracellular stimulusGO:00099913800.012
negative regulation of cell differentiationGO:0045596990.012
positive regulation of phosphate metabolic processGO:00459372620.012

Ireb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.018
central nervous system diseaseDOID:33100.018
disease of anatomical entityDOID:700.018
cancerDOID:16200.016
organ system cancerDOID:005068600.016
gastrointestinal system cancerDOID:311900.016
disease of cellular proliferationDOID:1456600.016
large intestine cancerDOID:567200.013
colon carcinomaDOID:152000.013
colon cancerDOID:21900.013
colorectal cancerDOID:925600.013
intestinal cancerDOID:1015500.013