Rattus norvegicus

0 known processes

Spint1

serine peptidase inhibitor, Kunitz type 1

(Aliases: HAI-1)

Spint1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of signalingGO:00230562700.080
oxoacid metabolic processGO:00434362900.075
rna biosynthetic processGO:00327743800.069
intracellular signal transductionGO:00355563140.069
regulation of signal transductionGO:00099663180.066
purine nucleotide metabolic processGO:00061632290.065
regulation of cellular component organizationGO:00511283680.064
neuron differentiationGO:00301823680.063
cellular amino acid metabolic processGO:00065201070.061
organic substance catabolic processGO:19015753160.060
regulation of rna metabolic processGO:00512523910.057
negative regulation of metabolic processGO:00098923310.056
carboxylic acid metabolic processGO:00197522890.055
regulation of cellular amine metabolic processGO:003323880.055
positive regulation of response to stimulusGO:00485842850.053
organic acid metabolic processGO:00060822920.052
catabolic processGO:00090563510.051
cellular ketone metabolic processGO:0042180510.051
organelle organizationGO:00069962660.050
single organism organelle organizationGO:19025891800.050
nucleobase containing small molecule metabolic processGO:00550863160.048
regulation of cellular amino acid metabolic processGO:000652120.047
programmed cell deathGO:00125013920.047
regulation of cell developmentGO:00602842630.045
negative regulation of cell communicationGO:00106481580.045
response to acid chemicalGO:00011012220.044
negative regulation of macromolecule metabolic processGO:00106052600.042
regulation of apoptotic processGO:00429813350.041
regulation of rna biosynthetic processGO:20011413810.041
purine ribonucleotide metabolic processGO:00091502270.040
positive regulation of transportGO:00510502450.040
cellular response to endogenous stimulusGO:00714953770.040
rna metabolic processGO:00160704060.040
anatomical structure morphogenesisGO:00096532980.039
carbohydrate derivative metabolic processGO:19011353460.039
positive regulation of nitrogen compound metabolic processGO:00511733340.038
regulation of cell proliferationGO:00421273590.038
regulation of cellular ketone metabolic processGO:0010565270.038
nucleotide metabolic processGO:00091172790.038
macromolecular complex subunit organizationGO:00439333390.038
cellular component assemblyGO:00226073600.037
regulation of nucleic acid templated transcriptionGO:19035063800.037
purine containing compound metabolic processGO:00725212530.037
regulation of transcription dna templatedGO:00063553740.037
regulation of molecular functionGO:00650093980.037
regulation of nervous system developmentGO:00519602640.036
response to metal ionGO:00100382530.036
response to ketoneGO:19016541820.036
homeostatic processGO:00425923310.036
cellular amine metabolic processGO:0044106380.036
vesicle mediated transportGO:00161921810.035
cellular response to oxygen containing compoundGO:19017013860.035
single organism catabolic processGO:00447122830.035
organophosphate metabolic processGO:00196373700.034
response to estrogenGO:00436272320.034
macromolecular complex assemblyGO:00650032730.034
regulation of neurogenesisGO:00507672470.034
negative regulation of cellular metabolic processGO:00313242810.034
positive regulation of nucleobase containing compound metabolic processGO:00459353190.034
negative regulation of nitrogen compound metabolic processGO:00511721610.033
response to corticosteroidGO:00319602350.033
regulation of multicellular organismal developmentGO:20000263760.033
negative regulation of gene expressionGO:00106291990.033
nucleic acid templated transcriptionGO:00976593790.033
amine metabolic processGO:0009308380.033
cellular component movementGO:00069282480.033
response to nutrient levelsGO:00316673700.033
negative regulation of transcription dna templatedGO:00458921160.032
negative regulation of signalingGO:00230571570.032
nucleoside phosphate metabolic processGO:00067532830.032
defense responseGO:00069521940.032
anion transportGO:00068201780.032
regulation of phosphorylationGO:00423252480.032
positive regulation of cell communicationGO:00106472710.032
brain developmentGO:00074202470.031
positive regulation of biosynthetic processGO:00098913190.031
locomotionGO:00400112370.031
regulation of protein modification processGO:00313991940.031
negative regulation of cellular biosynthetic processGO:00313271610.031
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.030
neuron developmentGO:00486662860.030
regulation of programmed cell deathGO:00430673410.030
response to inorganic substanceGO:00100353770.029
negative regulation of biosynthetic processGO:00098901680.029
transcription dna templatedGO:00063513770.029
apoptotic processGO:00069153810.029
negative regulation of cell deathGO:00605482290.029
single organism reproductive processGO:00447022970.029
heterocycle catabolic processGO:00467001670.029
positive regulation of cellular amino acid metabolic processGO:004576410.029
ribose phosphate metabolic processGO:00196932350.029
ribonucleotide catabolic processGO:00092611360.029
cellular catabolic processGO:00442482950.029
regulation of intracellular signal transductionGO:19025312180.028
central nervous system developmentGO:00074173110.028
regulation of catalytic activityGO:00507903040.028
tissue developmentGO:00098882520.028
regulation of cell differentiationGO:00455953200.027
response to extracellular stimulusGO:00099913800.027
cellular response to lipidGO:00713962010.027
multi organism reproductive processGO:00447032620.027
peptidyl amino acid modificationGO:00181931260.027
cardiovascular system developmentGO:00723581340.027
positive regulation of gene expressionGO:00106282440.027
protein complex biogenesisGO:00702712630.027
regulation of system processGO:00440572080.027
g protein coupled receptor signaling pathwayGO:00071862420.027
cellular response to organic cyclic compoundGO:00714072020.026
positive regulation of phosphate metabolic processGO:00459372620.026
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.026
ribonucleotide metabolic processGO:00092592310.026
negative regulation of multicellular organismal processGO:00512412030.026
positive regulation of rna biosynthetic processGO:19026801970.026
regulation of cell projection organizationGO:00313441750.026
response to mechanical stimulusGO:00096121340.026
reproductive processGO:00224143720.026
synaptic transmissionGO:00072682350.026
cellular component biogenesisGO:00440853680.026
negative regulation of macromolecule biosynthetic processGO:00105581480.025
hormone secretionGO:00468791150.025
positive regulation of cellular component organizationGO:00511302000.025
transcription from rna polymerase ii promoterGO:00063662520.025
response to bacteriumGO:00096172000.025
head developmentGO:00603222470.025
developmental process involved in reproductionGO:00030061590.025
cell migrationGO:00164771970.025
positive regulation of phosphorus metabolic processGO:00105622620.025
positive regulation of transcription dna templatedGO:00458931970.025
nitrogen compound transportGO:00717052290.025
multicellular organism reproductionGO:00325042330.025
glycosyl compound metabolic processGO:19016571820.025
agingGO:00075682410.025
organonitrogen compound biosynthetic processGO:19015661670.025
protein phosphorylationGO:00064683450.025
negative regulation of rna biosynthetic processGO:19026791180.024
cellular cation homeostasisGO:00300031800.024
nucleoside metabolic processGO:00091161790.024
positive regulation of multicellular organismal processGO:00512403870.024
carbohydrate derivative catabolic processGO:19011361470.024
regulation of neuron differentiationGO:00456642080.024
positive regulation of molecular functionGO:00440932300.024
protein complex subunit organizationGO:00718223020.024
neuron projection developmentGO:00311752730.024
regulation of phosphate metabolic processGO:00192203490.024
positive regulation of signal transductionGO:00099671750.023
positive regulation of cellular amine metabolic processGO:003324030.023
mapk cascadeGO:00001651400.023
transmembrane transportGO:00550854120.023
chemical homeostasisGO:00488782920.023
response to external biotic stimulusGO:00432072210.023
nucleoside triphosphate metabolic processGO:00091411440.023
muscle contractionGO:0006936880.023
regulation of secretion by cellGO:19035302080.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
positive regulation of cell differentiationGO:00455972170.022
positive regulation of rna metabolic processGO:00512542030.022
organic cyclic compound catabolic processGO:19013611750.022
positive regulation of cytosolic calcium ion concentrationGO:00072041220.022
regulation of kinase activityGO:00435491170.022
response to peptideGO:19016522920.022
protein localizationGO:00081041910.022
response to monosaccharideGO:00342841590.022
positive regulation of protein phosphorylationGO:00019341350.022
regulation of protein phosphorylationGO:00019321830.022
secretion by cellGO:00329402480.022
positive regulation of catalytic activityGO:00430851840.022
cellular calcium ion homeostasisGO:00068741600.022
positive regulation of cellular biosynthetic processGO:00313282950.022
forebrain developmentGO:0030900980.021
aromatic compound catabolic processGO:00194391680.021
regulation of mapk cascadeGO:00434081160.021
positive regulation of cell developmentGO:00107201760.021
cation homeostasisGO:00550801950.021
ribonucleoside metabolic processGO:00091191740.021
positive regulation of protein metabolic processGO:00512471780.021
circulatory system processGO:00030131830.021
regulation of cellular protein metabolic processGO:00322682670.021
regulation of neuron projection developmentGO:00109751610.021
regulation of transcription from rna polymerase ii promoterGO:00063572340.021
regulation of phosphorus metabolic processGO:00511743490.021
muscle structure developmentGO:0061061870.020
cellular response to nitrogen compoundGO:19016992100.020
negative regulation of signal transductionGO:0009968830.020
negative regulation of response to stimulusGO:00485851550.020
response to hypoxiaGO:00016662310.020
regulation of protein metabolic processGO:00512462890.020
cellular response to hormone stimulusGO:00328702470.020
gland developmentGO:00487321550.020
negative regulation of developmental processGO:00510931250.020
regulation of anatomical structure sizeGO:00900661350.020
positive regulation of intracellular signal transductionGO:19025331380.020
cellular chemical homeostasisGO:00550822470.020
secretionGO:00469033070.020
positive regulation of programmed cell deathGO:00430681570.019
cell cell signalingGO:00072673350.019
response to vitaminGO:00332731310.019
positive regulation of cell proliferationGO:00082842490.019
regulation of hydrolase activityGO:00513361430.019
negative regulation of nucleic acid templated transcriptionGO:19035071170.019
response to cytokineGO:00340972150.019
single organism biosynthetic processGO:00447113420.019
macromolecule localizationGO:00330362520.019
gastrulationGO:000736920.019
negative regulation of programmed cell deathGO:00430691830.019
nucleobase containing compound catabolic processGO:00346551520.019
protein complex assemblyGO:00064612630.019
regulation of neuron apoptotic processGO:0043523830.019
calcium ion homeostasisGO:00550741620.019
organophosphate catabolic processGO:00464341480.019
amide transportGO:00428861050.019
multicellular organismal reproductive processGO:00486092330.019
cell projection organizationGO:00300303020.019
positive regulation of cell deathGO:00109421840.018
cellular homeostasisGO:00197252520.018
positive regulation of protein modification processGO:00314011420.018
positive regulation of secretionGO:00510471400.018
regulation of synaptic transmissionGO:00508041410.018
endocytosisGO:0006897840.018
response to glucoseGO:00097491360.018
regulation of peptide hormone secretionGO:0090276800.018
cellular ion homeostasisGO:00068731840.018
divalent inorganic cation homeostasisGO:00725071650.018
neuron deathGO:00709971270.018
purine nucleotide catabolic processGO:00061951360.018
response to decreased oxygen levelsGO:00362932370.018
regulation of establishment of planar polarityGO:009017520.018
response to glucocorticoidGO:00513842230.018
response to carbohydrateGO:00097431830.017
cellular nitrogen compound catabolic processGO:00442701630.017
gliogenesisGO:0042063930.017
positive regulation of nucleotide metabolic processGO:0045981910.017
response to oxygen levelsGO:00704822650.017
ion homeostasisGO:00508012120.017
organonitrogen compound catabolic processGO:19015651790.017
signal releaseGO:00230611450.017
nucleotide catabolic processGO:00091661390.017
single organism intracellular transportGO:19025821660.017
response to hexoseGO:00097461440.017
ion transmembrane transportGO:00342203650.017
positive regulation of phosphorylationGO:00423271770.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
oxidation reduction processGO:00551143040.016
regulation of neuron deathGO:19012141150.016
positive regulation of locomotionGO:00400171020.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
regulation of catabolic processGO:00098941130.016
intracellular transportGO:00469071850.016
cell type specific apoptotic processGO:00972851340.016
cell cell junction organizationGO:0045216200.016
regulation of transferase activityGO:00513381230.016
positive regulation of kinase activityGO:0033674770.016
nucleoside phosphate biosynthetic processGO:19012931020.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
purine ribonucleoside metabolic processGO:00461281680.016
regulation of tube sizeGO:0035150890.016
cellular response to stressGO:00335542690.016
carbohydrate metabolic processGO:00059751300.016
nucleoside triphosphate catabolic processGO:00091431230.016
response to other organismGO:00517072200.016
cytosolic calcium ion homeostasisGO:00514801400.016
positive regulation of cellular protein metabolic processGO:00322701670.015
gamete generationGO:00072761240.015
neuron projection morphogenesisGO:00488121220.015
negative regulation of neurogenesisGO:0050768780.015
response to nutrientGO:00075842480.015
regulation of vesicle mediated transportGO:0060627810.015
regulation of cellular localizationGO:00603412630.015
positive regulation of developmental processGO:00510942830.015
cellular response to external stimulusGO:00714961180.015
female pregnancyGO:00075651220.015
regulation of blood vessel sizeGO:0050880890.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
hormone transportGO:00099141210.015
negative regulation of rna metabolic processGO:00512531230.015
establishment of protein localizationGO:00451841410.015
purine containing compound catabolic processGO:00725231380.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
regulation of hormone levelsGO:00108171870.015
small gtpase mediated signal transductionGO:0007264360.015
metal ion homeostasisGO:00550651860.015
regulation of anatomical structure morphogenesisGO:00226031410.015
actin cytoskeleton organizationGO:0030036730.015
purine nucleoside metabolic processGO:00422781690.015
neuron apoptotic processGO:0051402880.015
response to toxic substanceGO:00096361330.015
positive regulation of mapk cascadeGO:0043410920.015
cellular response to cytokine stimulusGO:00713451270.015
response to radiationGO:00093141370.015
cellular protein localizationGO:00346131220.015
vascular process in circulatory systemGO:0003018960.015
response to alkaloidGO:00432791320.015
cellular response to alcoholGO:0097306870.015
proteolysisGO:00065081750.014
actin filament based processGO:0030029860.014
response to ethanolGO:00454711620.014
purine nucleoside triphosphate catabolic processGO:00091461220.014
regulation of peptide secretionGO:0002791820.014
organic anion transportGO:00157111320.014
wound healingGO:00420601220.014
anatomical structure formation involved in morphogenesisGO:0048646830.014
glial cell differentiationGO:0010001650.014
immune responseGO:00069551040.014
non canonical wnt signaling pathwayGO:003556730.014
response to peptide hormoneGO:00434342780.014
sexual reproductionGO:00199531480.014
response to purine containing compoundGO:00140741260.014
purine nucleoside catabolic processGO:00061521240.014
organ regenerationGO:00311001010.014
regulation of nucleotide metabolic processGO:00061401170.014
nucleoside catabolic processGO:00091641260.014
cell adhesionGO:00071551100.014
regulation of secretionGO:00510462240.014
cell part morphogenesisGO:00329901230.014
localization of cellGO:00516742020.014
nucleoside phosphate catabolic processGO:19012921400.014
carbohydrate derivative biosynthetic processGO:19011371240.014
cell growthGO:00160491040.014
glycosyl compound catabolic processGO:19016581260.014
nucleotide biosynthetic processGO:0009165980.014
cellular metal ion homeostasisGO:00068751720.014
regulation of immune system processGO:00026821230.014
neurological system processGO:00508772190.014
epithelium developmentGO:0060429960.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.014
negative regulation of cellular component organizationGO:0051129830.014
peptide transportGO:0015833970.014
negative regulation of viral processGO:004852540.014
response to woundingGO:00096112540.013
formation of primary germ layerGO:000170410.013
behaviorGO:00076102050.013
mesoderm developmentGO:000749820.013
ras protein signal transductionGO:0007265290.013
ribonucleoside catabolic processGO:00424541260.013
establishment of tissue polarityGO:000716420.013
blood circulationGO:00080151830.013
multi multicellular organism processGO:00447061380.013
purine ribonucleoside catabolic processGO:00461301240.013
regulation of organelle organizationGO:0033043800.013
negative regulation of apoptotic processGO:00430661810.013
negative regulation of cell differentiationGO:0045596990.013
cellular response to organonitrogen compoundGO:00714171970.013
positive regulation of neurogenesisGO:00507691650.013
positive regulation of immune system processGO:0002684900.013
peptidyl tyrosine phosphorylationGO:0018108720.013
regulation of cell growthGO:0001558850.013
negative regulation of organ growthGO:004662130.013
positive regulation of cell projection organizationGO:00313461110.013
divalent inorganic cation transportGO:00725111340.013
protein homooligomerizationGO:0051260910.013
cytoskeleton organizationGO:00070101110.013
ribonucleotide biosynthetic processGO:0009260850.013
signal transduction by phosphorylationGO:00230141440.013
metal ion transportGO:00300012890.013
positive regulation of neuron differentiationGO:00456661260.012
positive regulation of nervous system developmentGO:00519621780.012
cellular macromolecule localizationGO:00707271220.012
epithelial cell differentiationGO:0030855710.012
response to estradiolGO:00323551640.012
peptide hormone secretionGO:0030072840.012
growthGO:00400071650.012
reproductionGO:00000032450.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
embryonic pattern specificationGO:000988010.012
circulatory system developmentGO:00723591340.012
single organism membrane organizationGO:0044802740.012
protein transportGO:00150311320.012
maintenance of locationGO:0051235170.012
regulation of canonical wnt signaling pathwayGO:006082840.012
defense response to gram negative bacteriumGO:005082930.012
eye morphogenesisGO:004859240.012
cytoplasmic transportGO:00164821150.012
axis specificationGO:000979840.012
erbb signaling pathwayGO:0038127230.012
regulation of hormone secretionGO:00468831060.012
muscle system processGO:00030121150.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
calcium ion transportGO:00068161310.012
regulation of response to stressGO:00801341260.012
chromosome segregationGO:000705920.012
response to growth factorGO:00708481890.012
positive regulation of protein kinase activityGO:0045860730.012
cellular response to abiotic stimulusGO:0071214850.012
regulation of response to external stimulusGO:00321011060.012
negative regulation of cell proliferationGO:00082851190.012
cellular macromolecular complex assemblyGO:0034622580.012
exocytosisGO:0006887600.012
purine containing compound biosynthetic processGO:0072522850.012
regulation of blood circulationGO:19035221100.012
multicellular organism growthGO:003526410.012
rho protein signal transductionGO:0007266110.011
regulation of purine nucleotide metabolic processGO:19005421150.011
purine nucleotide biosynthetic processGO:0006164830.011
regulation of smooth muscle cell proliferationGO:0048660750.011
cell motilityGO:00488702020.011
negative regulation of nervous system developmentGO:0051961790.011
regulation of peptide transportGO:0090087870.011
muscle cell proliferationGO:0033002840.011
regulation of cyclic nucleotide metabolic processGO:0030799510.011
cellular response to metal ionGO:0071248550.011
positive regulation of secretion by cellGO:19035321280.011
reactive nitrogen species metabolic processGO:200105710.011
reactive oxygen species biosynthetic processGO:190340980.011
protein oligomerizationGO:00512591910.011
cation transportGO:00068123820.011
positive regulation of apoptotic processGO:00430651540.011
regulation of calcium ion transportGO:0051924770.011
ribose phosphate biosynthetic processGO:0046390870.011
establishment of planar polarityGO:000173610.011
reactive oxygen species metabolic processGO:0072593370.011
negative regulation of neuron differentiationGO:0045665620.011
regulation of membrane potentialGO:00423911100.011
peptidyl tyrosine modificationGO:0018212720.011
positive regulation of transferase activityGO:0051347810.011
regulation of body fluid levelsGO:0050878900.011
positive regulation of nucleoside metabolic processGO:0045979550.011
single organism carbohydrate metabolic processGO:00447231180.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
muscle cell differentiationGO:0042692520.011
regulation of locomotionGO:00400121480.010
sex differentiationGO:00075481130.010
peptide secretionGO:0002790860.010
positive regulation of hormone secretionGO:0046887650.010
morphogenesis of a polarized epitheliumGO:000173810.010
regenerationGO:00310991630.010
single organism cellular localizationGO:19025801020.010
response to molecule of bacterial originGO:00022371940.010
regulation of map kinase activityGO:0043405530.010
sensory perception of painGO:0019233730.010
acid secretionGO:0046717480.010
chromosome organizationGO:0051276360.010
regulation of muscle system processGO:0090257790.010
regulation of fat cell differentiationGO:004559830.010
regulation of protein kinase activityGO:00458591050.010
reproductive structure developmentGO:00486081280.010
smooth muscle contractionGO:0006939370.010
anterior posterior pattern specificationGO:000995210.010
positive regulation of peptide secretionGO:0002793520.010
chemotaxisGO:0006935660.010
inflammatory responseGO:00069541500.010
response to retinoic acidGO:0032526630.010
tube developmentGO:0035295890.010

Spint1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.035
disease of anatomical entityDOID:700.035
sensory system diseaseDOID:005015500.020
disease of metabolismDOID:001466700.017
musculoskeletal system diseaseDOID:1700.017
central nervous system diseaseDOID:33100.014
gastrointestinal system diseaseDOID:7700.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011