IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Pik3ip1

phosphoinositide-3-kinase interacting protein 1

(Aliases: RGD1311203,zgc:66482)

Ensembl: ENSRNOG00000018859
Entrez: 305472
RGD: 1311203
UniProtKB: Q56A20

Process Predictions
Disease Predictions

Pik3ip1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of cell proliferation	GO:0042127	359	0.310
regulation of phosphorus metabolic process	GO:0051174	349	0.209	Human Mouse
negative regulation of cellular metabolic process	GO:0031324	281	0.197	Human Mouse
regulation of rna biosynthetic process	GO:2001141	381	0.142
nucleic acid templated transcription	GO:0097659	379	0.135
regulation of phosphate metabolic process	GO:0019220	349	0.122	Human Mouse
protein phosphorylation	GO:0006468	345	0.113
membrane repolarization	GO:0086009	1	0.113
regulation of rna metabolic process	GO:0051252	391	0.112
regulation of nucleic acid templated transcription	GO:1903506	380	0.097
response to hypoxia	GO:0001666	231	0.090
response to inorganic substance	GO:0010035	377	0.085
regulation of protein modification process	GO:0031399	194	0.083
regulation of cellular protein metabolic process	GO:0032268	267	0.080
immune system process	GO:0002376	204	0.075
rna metabolic process	GO:0016070	406	0.071
positive regulation of phosphorus metabolic process	GO:0010562	262	0.068
regulation of protein phosphorylation	GO:0001932	183	0.068
regulation of molecular function	GO:0065009	398	0.067	Human Mouse
nucleoside phosphate metabolic process	GO:0006753	283	0.063
renal system development	GO:0072001	67	0.062
transcription dna templated	GO:0006351	377	0.060
negative regulation of cell proliferation	GO:0008285	119	0.059
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.059
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.058
positive regulation of phosphate metabolic process	GO:0045937	262	0.055
neuron projection development	GO:0031175	273	0.055
positive regulation of biosynthetic process	GO:0009891	319	0.054
programmed cell death	GO:0012501	392	0.054
regulation of cellular amine metabolic process	GO:0033238	8	0.050
response to ketone	GO:1901654	182	0.050
negative regulation of macromolecule metabolic process	GO:0010605	260	0.050
rna biosynthetic process	GO:0032774	380	0.049
reproductive system development	GO:0061458	128	0.048
regulation of protein metabolic process	GO:0051246	289	0.048
negative regulation of gene expression	GO:0010629	199	0.047
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.046
negative regulation of metabolic process	GO:0009892	331	0.045	Human Mouse
regulation of cellular amino acid metabolic process	GO:0006521	2	0.043
regulation of kinase activity	GO:0043549	117	0.043	Human Mouse
cellular response to lipid	GO:0071396	201	0.043
positive regulation of cell communication	GO:0010647	271	0.042
organophosphate metabolic process	GO:0019637	370	0.042	Human Mouse
signal transduction by phosphorylation	GO:0023014	144	0.042
reproductive process	GO:0022414	372	0.042
positive regulation of cellular protein metabolic process	GO:0032270	167	0.041
regulation of cellular localization	GO:0060341	263	0.041
regulation of immune system process	GO:0002682	123	0.040
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.040
cardiac chamber development	GO:0003205	1	0.039
purine containing compound biosynthetic process	GO:0072522	85	0.037
positive regulation of gene expression	GO:0010628	244	0.037
reproductive structure development	GO:0048608	128	0.036
regulation of transcription dna templated	GO:0006355	374	0.036
catabolic process	GO:0009056	351	0.035
intracellular transport	GO:0046907	185	0.033
oxoacid metabolic process	GO:0043436	290	0.033
positive regulation of phosphorylation	GO:0042327	177	0.032
endocytosis	GO:0006897	84	0.032
homeostatic process	GO:0042592	331	0.031
mapk cascade	GO:0000165	140	0.030
positive regulation of protein modification process	GO:0031401	142	0.030
transcription from rna polymerase ii promoter	GO:0006366	252	0.030
response to metal ion	GO:0010038	253	0.030
positive regulation of cell death	GO:0010942	184	0.030
regulation of cellular component organization	GO:0051128	368	0.030
regulation of apoptotic process	GO:0042981	335	0.030
anatomical structure morphogenesis	GO:0009653	298	0.029
positive regulation of protein metabolic process	GO:0051247	178	0.029
vesicle mediated transport	GO:0016192	181	0.029
regulation of cellular ketone metabolic process	GO:0010565	27	0.029
cellular ketone metabolic process	GO:0042180	51	0.028
multi organism reproductive process	GO:0044703	262	0.028
positive regulation of rna metabolic process	GO:0051254	203	0.027
organonitrogen compound biosynthetic process	GO:1901566	167	0.027
positive regulation of transferase activity	GO:0051347	81	0.027
regulation of intracellular signal transduction	GO:1902531	218	0.027	Human Mouse
defense response	GO:0006952	194	0.027
negative regulation of cell communication	GO:0010648	158	0.026	Human Mouse
peptidyl amino acid modification	GO:0018193	126	0.026
purine containing compound metabolic process	GO:0072521	253	0.026
positive regulation of transcription dna templated	GO:0045893	197	0.026
protein complex subunit organization	GO:0071822	302	0.026
response to oxygen levels	GO:0070482	265	0.026
regulation of cell maturation	GO:1903429	3	0.026
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.026
purine nucleotide biosynthetic process	GO:0006164	83	0.025
cellular amine metabolic process	GO:0044106	38	0.024
cellular response to endogenous stimulus	GO:0071495	377	0.024
positive regulation of cellular component movement	GO:0051272	102	0.024
positive regulation of cellular amine metabolic process	GO:0033240	3	0.024
positive regulation of protein phosphorylation	GO:0001934	135	0.024
organelle organization	GO:0006996	266	0.024
protein maturation	GO:0051604	68	0.024
apoptotic process	GO:0006915	381	0.023
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.023
positive regulation of signaling	GO:0023056	270	0.023
ribose phosphate biosynthetic process	GO:0046390	87	0.023
regulation of cell differentiation	GO:0045595	320	0.023
negative regulation of cellular biosynthetic process	GO:0031327	161	0.023
positive regulation of rna biosynthetic process	GO:1902680	197	0.023
purine nucleotide metabolic process	GO:0006163	229	0.023
cell migration	GO:0016477	197	0.023
regulation of phosphorylation	GO:0042325	248	0.023	Human Mouse
striated muscle contraction	GO:0006941	44	0.023
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.022
regulation of membrane repolarization	GO:0060306	1	0.022
positive regulation of molecular function	GO:0044093	230	0.022
regulation of protein kinase activity	GO:0045859	105	0.022
carboxylic acid metabolic process	GO:0019752	289	0.021
regulation of synaptic transmission	GO:0050804	141	0.021
positive regulation of multicellular organismal process	GO:0051240	387	0.021
regulation of system process	GO:0044057	208	0.021
proteolysis	GO:0006508	175	0.021
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.021
positive regulation of blood circulation	GO:1903524	65	0.021
ras protein signal transduction	GO:0007265	29	0.020
single organism biosynthetic process	GO:0044711	342	0.020
negative regulation of biosynthetic process	GO:0009890	168	0.020
positive regulation of purine nucleotide biosynthetic process	GO:1900373	36	0.020
mammary gland development	GO:0030879	38	0.020
nucleoside phosphate biosynthetic process	GO:1901293	102	0.020
positive regulation of cyclic nucleotide metabolic process	GO:0030801	37	0.020
nucleotide metabolic process	GO:0009117	279	0.020
response to peptide hormone	GO:0043434	278	0.020
regulation of catalytic activity	GO:0050790	304	0.020	Human Mouse
cell projection organization	GO:0030030	302	0.019
regulation of canonical wnt signaling pathway	GO:0060828	4	0.019
metal ion transport	GO:0030001	289	0.019
muscle system process	GO:0003012	115	0.019
nitrogen compound transport	GO:0071705	229	0.019
positive regulation of cell proliferation	GO:0008284	249	0.019
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.019
nucleotide biosynthetic process	GO:0009165	98	0.019
response to amino acid	GO:0043200	75	0.019
cell activation	GO:0001775	97	0.018
single organism catabolic process	GO:0044712	283	0.018
positive regulation of cellular biosynthetic process	GO:0031328	295	0.018
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	34	0.018
cellular response to oxygen containing compound	GO:1901701	386	0.018
cellular response to hormone stimulus	GO:0032870	247	0.018
regulation of skeletal muscle tissue regeneration	GO:0043416	2	0.018
g protein coupled receptor signaling pathway	GO:0007186	242	0.018
regulation of smooth muscle cell proliferation	GO:0048660	75	0.018
purine ribonucleotide biosynthetic process	GO:0009152	81	0.018
cellular amino acid metabolic process	GO:0006520	107	0.018
cellular macromolecular complex assembly	GO:0034622	58	0.018
response to reactive oxygen species	GO:0000302	120	0.018
peptide hormone secretion	GO:0030072	84	0.018
positive regulation of signal transduction	GO:0009967	175	0.017
small gtpase mediated signal transduction	GO:0007264	36	0.017
cardiac ventricle development	GO:0003231	1	0.017
regulation of cyclic nucleotide metabolic process	GO:0030799	51	0.017
regulation of cell morphogenesis	GO:0022604	77	0.017
receptor mediated endocytosis	GO:0006898	42	0.017
regulation of membrane potential	GO:0042391	110	0.017
chemical homeostasis	GO:0048878	292	0.017
negative regulation of multicellular organismal process	GO:0051241	203	0.017
protein complex assembly	GO:0006461	263	0.017
cellular component movement	GO:0006928	248	0.017
cellular response to growth factor stimulus	GO:0071363	162	0.017
peptide secretion	GO:0002790	86	0.017
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.017
maintenance of location	GO:0051235	17	0.017
regulation of cell motility	GO:2000145	131	0.017
secretion	GO:0046903	307	0.017
positive regulation of programmed cell death	GO:0043068	157	0.017
carbohydrate derivative metabolic process	GO:1901135	346	0.017
organic substance catabolic process	GO:1901575	316	0.017
amide transport	GO:0042886	105	0.016
positive regulation of kinase activity	GO:0033674	77	0.016
amine metabolic process	GO:0009308	38	0.016
action potential	GO:0001508	54	0.016
single organism organelle organization	GO:1902589	180	0.016
positive regulation of protein kinase activity	GO:0045860	73	0.016
hormone secretion	GO:0046879	115	0.016
regulation of signal transduction	GO:0009966	318	0.016	Human Mouse
circulatory system development	GO:0072359	134	0.016
positive regulation of camp metabolic process	GO:0030816	31	0.016
regulation of cell adhesion	GO:0030155	52	0.016
protein heterooligomerization	GO:0051291	89	0.016
regulation of homeostatic process	GO:0032844	101	0.016
purine ribonucleotide metabolic process	GO:0009150	227	0.016
negative regulation of cell differentiation	GO:0045596	99	0.016
response to carbohydrate	GO:0009743	183	0.016
regulation of hydrolase activity	GO:0051336	143	0.016
positive regulation of developmental process	GO:0051094	283	0.016
response to decreased oxygen levels	GO:0036293	237	0.015
sex differentiation	GO:0007548	113	0.015
gonad development	GO:0008406	104	0.015
cardiac muscle cell action potential involved in contraction	GO:0086002	2	0.015
response to oxidative stress	GO:0006979	186	0.015
blood circulation	GO:0008015	183	0.015
neuron differentiation	GO:0030182	368	0.015
muscle structure development	GO:0061061	87	0.015
aging	GO:0007568	241	0.015
neurological system process	GO:0050877	219	0.015
positive regulation of catalytic activity	GO:0043085	184	0.015
oxidation reduction process	GO:0055114	304	0.015
cellular response to abiotic stimulus	GO:0071214	85	0.015
single organism intracellular transport	GO:1902582	166	0.015
intracellular signal transduction	GO:0035556	314	0.015	Human Mouse
organ morphogenesis	GO:0009887	75	0.015
single organism reproductive process	GO:0044702	297	0.015
regulation of peptide transport	GO:0090087	87	0.015
energy derivation by oxidation of organic compounds	GO:0015980	46	0.014
nucleobase containing small molecule metabolic process	GO:0055086	316	0.014
positive regulation of immune system process	GO:0002684	90	0.014
regulation of multicellular organismal development	GO:2000026	376	0.014
negative regulation of phosphorus metabolic process	GO:0010563	80	0.014	Human Mouse
response to glucose	GO:0009749	136	0.014
negative regulation of protein metabolic process	GO:0051248	114	0.014
negative regulation of immune system process	GO:0002683	39	0.014
ribose phosphate metabolic process	GO:0019693	235	0.014
ion transmembrane transport	GO:0034220	365	0.014
positive regulation of response to stimulus	GO:0048584	285	0.014
skeletal muscle tissue development	GO:0007519	31	0.014
regulation of secretion	GO:0051046	224	0.014
hepaticobiliary system development	GO:0061008	90	0.014
regulation of transferase activity	GO:0051338	123	0.014	Human Mouse
defense response to gram positive bacterium	GO:0050830	2	0.014
regulation of cyclic nucleotide biosynthetic process	GO:0030802	45	0.014
macromolecular complex subunit organization	GO:0043933	339	0.013
developmental process involved in reproduction	GO:0003006	159	0.013
skeletal muscle organ development	GO:0060538	33	0.013
regulation of neuron projection development	GO:0010975	161	0.013
regulation of cellular component movement	GO:0051270	150	0.013
negative regulation of rna metabolic process	GO:0051253	123	0.013
positive regulation of cell differentiation	GO:0045597	217	0.013
regulation of catabolic process	GO:0009894	113	0.013
negative regulation of transport	GO:0051051	136	0.013
negative regulation of signaling	GO:0023057	157	0.013	Human Mouse
regulation of programmed cell death	GO:0043067	341	0.013
protein complex biogenesis	GO:0070271	263	0.013
transmission of nerve impulse	GO:0019226	42	0.013
response to hexose	GO:0009746	144	0.013
dephosphorylation	GO:0016311	98	0.013
response to low density lipoprotein particle	GO:0055098	4	0.013
regulation of striated muscle contraction	GO:0006942	21	0.013
negative regulation of secretion	GO:0051048	82	0.013
response to mechanical stimulus	GO:0009612	134	0.013
heart contraction	GO:0060047	57	0.013
negative regulation of developmental process	GO:0051093	125	0.013
localization of cell	GO:0051674	202	0.013
cellular catabolic process	GO:0044248	295	0.013
bmp signaling pathway	GO:0030509	4	0.013
neuron development	GO:0048666	286	0.013
neuron projection morphogenesis	GO:0048812	122	0.012
regulation of cell cycle	GO:0051726	73	0.012
muscle contraction	GO:0006936	88	0.012
regulation of endothelial cell differentiation	GO:0045601	4	0.012
dopamine metabolic process	GO:0042417	12	0.012
regulation of body fluid levels	GO:0050878	90	0.012
smooth muscle cell proliferation	GO:0048659	77	0.012
regulation of nucleotide metabolic process	GO:0006140	117	0.012
response to acid chemical	GO:0001101	222	0.012
regulation of nervous system development	GO:0051960	264	0.012
macromolecular complex assembly	GO:0065003	273	0.012
positive regulation of camp biosynthetic process	GO:0030819	28	0.012
regulation of camp biosynthetic process	GO:0030817	38	0.012
positive regulation of transport	GO:0051050	245	0.012
cellular carbohydrate metabolic process	GO:0044262	72	0.012
cell cycle	GO:0007049	101	0.012
carbohydrate metabolic process	GO:0005975	130	0.012
nucleosome organization	GO:0034728	1	0.012
regulation of bmp signaling pathway	GO:0030510	2	0.012
membrane organization	GO:0061024	94	0.012
regulation of blood circulation	GO:1903522	110	0.012
cellular protein localization	GO:0034613	122	0.012
common partner smad protein phosphorylation	GO:0007182	1	0.012
cation transmembrane transport	GO:0098655	263	0.012
peptide transport	GO:0015833	97	0.012
positive regulation of secretion by cell	GO:1903532	128	0.012
carbohydrate derivative biosynthetic process	GO:1901137	124	0.011
transmembrane transport	GO:0055085	412	0.011
regulation of vesicle mediated transport	GO:0060627	81	0.011
regulation of purine nucleotide biosynthetic process	GO:1900371	46	0.011
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.011
cell motility	GO:0048870	202	0.011
fibroblast proliferation	GO:0048144	22	0.011
synaptic transmission	GO:0007268	235	0.011
dna metabolic process	GO:0006259	96	0.011
regulation of fat cell differentiation	GO:0045598	3	0.011
cyclic nucleotide biosynthetic process	GO:0009190	63	0.011
positive regulation of cellular component organization	GO:0051130	200	0.011
male gonad development	GO:0008584	59	0.011
regulation of muscle system process	GO:0090257	79	0.011
striated muscle tissue development	GO:0014706	58	0.011
lipid transport	GO:0006869	61	0.011
secretion by tissue	GO:0032941	37	0.011
response to monosaccharide	GO:0034284	159	0.011
protein oligomerization	GO:0051259	191	0.011
tube development	GO:0035295	89	0.011
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.011
negative regulation of cellular protein metabolic process	GO:0032269	106	0.011
cytoplasmic transport	GO:0016482	115	0.011
potassium ion transmembrane transport	GO:0071805	71	0.011
positive regulation of ion transport	GO:0043270	94	0.011
regulation of muscle contraction	GO:0006937	53	0.011
macromolecule catabolic process	GO:0009057	58	0.011
negative regulation of molecular function	GO:0044092	133	0.011	Human Mouse
development of primary male sexual characteristics	GO:0046546	59	0.011
jnk cascade	GO:0007254	28	0.010
regulation of ion transport	GO:0043269	245	0.010
nucleoside transport	GO:0015858	8	0.010
cellular nitrogen compound catabolic process	GO:0044270	163	0.010
regulation of cell migration	GO:0030334	128	0.010
response to other organism	GO:0051707	220	0.010
epithelium development	GO:0060429	96	0.010
relaxation of muscle	GO:0090075	4	0.010
circulatory system process	GO:0003013	183	0.010
central nervous system development	GO:0007417	311	0.010
single organism cellular localization	GO:1902580	102	0.010
cellular component morphogenesis	GO:0032989	155	0.010
response to fatty acid	GO:0070542	65	0.010
mitotic cell cycle	GO:0000278	49	0.010
response to radiation	GO:0009314	137	0.010
positive regulation of apoptotic process	GO:0043065	154	0.010
regulation of neurogenesis	GO:0050767	247	0.010
innate immune response	GO:0045087	35	0.010
positive regulation of nucleotide biosynthetic process	GO:0030810	36	0.010
protein localization to organelle	GO:0033365	57	0.010
regulation of hormone secretion	GO:0046883	106	0.010
heart morphogenesis	GO:0003007	3	0.010

Pik3ip1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
long qt syndrome	DOID:2843	0.030
disease of anatomical entity	DOID:7	0.020
nervous system disease	DOID:863	0.020
central nervous system disease	DOID:331	0.013

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