Rattus norvegicus

147 known processes

Igf1r

insulin-like growth factor 1 receptor

(Aliases: IGFIRC,JTK13)

Igf1r biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transcription dna templatedGO:00063513770.208
Mouse
cation transportGO:00068123820.192
negative regulation of biosynthetic processGO:00098901680.165
response to inorganic substanceGO:00100353770.163
Rat
negative regulation of cellular metabolic processGO:00313242810.157
Human Zebrafish Mouse Rat Fly
regulation of rna metabolic processGO:00512523910.151
Mouse
response to metal ionGO:00100382530.143
Rat
tissue developmentGO:00098882520.139
Zebrafish Mouse
response to decreased oxygen levelsGO:00362932370.129
Fly
rna biosynthetic processGO:00327743800.121
Mouse
ion transmembrane transportGO:00342203650.111
negative regulation of macromolecule metabolic processGO:00106052600.110
Human Zebrafish Rat
cellular response to organic cyclic compoundGO:00714072020.108
apoptotic processGO:00069153810.107
negative regulation of macromolecule biosynthetic processGO:00105581480.106
regulation of programmed cell deathGO:00430673410.104
transmembrane transportGO:00550854120.102
homeostatic processGO:00425923310.098
Rat Fly
protein complex subunit organizationGO:00718223020.094
regulation of nucleic acid templated transcriptionGO:19035063800.093
Mouse
response to hypoxiaGO:00016662310.093
nucleic acid templated transcriptionGO:00976593790.089
Mouse
anatomical structure morphogenesisGO:00096532980.086
metal ion transportGO:00300012890.086
epithelium developmentGO:0060429960.086
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063572340.084
secretionGO:00469033070.083
negative regulation of nitrogen compound metabolic processGO:00511721610.083
positive regulation of apoptotic processGO:00430651540.080
regulation of ion transportGO:00432692450.079
regulation of cell proliferationGO:00421273590.077
Fly
cellular response to endogenous stimulusGO:00714953770.077
Rat Fly
transcription from rna polymerase ii promoterGO:00063662520.077
positive regulation of signalingGO:00230562700.075
Human Mouse
cellular response to oxygen containing compoundGO:19017013860.072
Rat Fly
cellular component morphogenesisGO:00329891550.069
cell cell signalingGO:00072673350.069
programmed cell deathGO:00125013920.068
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.067
positive regulation of gene expressionGO:00106282440.067
response to oxygen levelsGO:00704822650.067
Fly
chemical homeostasisGO:00488782920.067
Rat
regulation of transcription dna templatedGO:00063553740.065
Mouse
regulation of rna biosynthetic processGO:20011413810.063
Mouse
cell morphogenesis involved in differentiationGO:00009041190.061
muscle system processGO:00030121150.060
regulation of membrane potentialGO:00423911100.060
positive regulation of rna metabolic processGO:00512542030.058
negative regulation of cellular biosynthetic processGO:00313271610.058
rna metabolic processGO:00160704060.057
Mouse
negative regulation of nucleobase containing compound metabolic processGO:00459341530.057
cation transmembrane transportGO:00986552630.056
cellular response to stressGO:00335542690.054
Human Worm Fly
negative regulation of transcription dna templatedGO:00458921160.054
epithelial cell differentiationGO:0030855710.053
calcium ion homeostasisGO:00550741620.053
negative regulation of gene expressionGO:00106291990.051
Zebrafish Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.050
negative regulation of metabolic processGO:00098923310.050
Human Zebrafish Mouse Rat Fly
macromolecular complex subunit organizationGO:00439333390.050
carbohydrate derivative metabolic processGO:19011353460.050
Rat
inorganic ion transmembrane transportGO:00986602290.049
growthGO:00400071650.049
Zebrafish Worm Fly
blood circulationGO:00080151830.048
positive regulation of multicellular organismal processGO:00512403870.048
Worm Fly
inorganic cation transmembrane transportGO:00986622020.047
regulation of multicellular organismal developmentGO:20000263760.047
positive regulation of biosynthetic processGO:00098913190.047
intracellular signal transductionGO:00355563140.046
Human Mouse
regulation of cellular localizationGO:00603412630.046
Worm
macromolecular complex assemblyGO:00650032730.046
developmental growthGO:00485891000.045
Zebrafish Worm Fly
cellular homeostasisGO:00197252520.045
response to growth factorGO:00708481890.045
ion homeostasisGO:00508012120.044
positive regulation of nucleobase containing compound metabolic processGO:00459353190.043
sensory organ developmentGO:0007423740.043
Zebrafish
axon developmentGO:0061564960.043
positive regulation of cell deathGO:00109421840.043
positive regulation of rna biosynthetic processGO:19026801970.043
response to cytokineGO:00340972150.042
Rat
cell projection morphogenesisGO:00488581230.042
negative regulation of rna metabolic processGO:00512531230.042
regulation of cell differentiationGO:00455953200.041
cell growthGO:00160491040.041
Fly
multicellular organism reproductionGO:00325042330.040
Zebrafish Worm Fly
negative regulation of nucleic acid templated transcriptionGO:19035071170.040
response to acid chemicalGO:00011012220.040
negative regulation of apoptotic processGO:00430661810.039
cellular response to organonitrogen compoundGO:00714171970.039
Rat Fly
positive regulation of programmed cell deathGO:00430681570.039
multi multicellular organism processGO:00447061380.038
Fly
reproductionGO:00000032450.038
Zebrafish Worm Fly
cation homeostasisGO:00550801950.038
regulation of secretionGO:00510462240.038
regulation of apoptotic processGO:00429813350.037
cellular chemical homeostasisGO:00550822470.037
positive regulation of cellular component organizationGO:00511302000.037
Mouse
regulation of nervous system developmentGO:00519602640.036
single organism reproductive processGO:00447022970.036
Zebrafish Mouse Worm Fly
response to nutrientGO:00075842480.035
regenerationGO:00310991630.035
Zebrafish
positive regulation of macromolecule biosynthetic processGO:00105572470.034
Human Rat
regulation of cell growthGO:0001558850.033
Fly
action potentialGO:0001508540.033
circulatory system processGO:00030131830.033
gland developmentGO:00487321550.033
Mouse
response to carbohydrateGO:00097431830.033
Rat
cellular component assemblyGO:00226073600.032
reproductive processGO:00224143720.032
Zebrafish Mouse Worm Fly
metal ion homeostasisGO:00550651860.032
neuron differentiationGO:00301823680.032
divalent inorganic cation homeostasisGO:00725071650.032
regulation of metal ion transportGO:00109591180.032
divalent metal ion transportGO:00708381320.032
calcium ion transportGO:00068161310.032
regulation of molecular functionGO:00650093980.031
Human Zebrafish Mouse Rat
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.031
cellular component biogenesisGO:00440853680.031
monovalent inorganic cation transportGO:00156721720.031
cellular response to growth factor stimulusGO:00713631620.030
positive regulation of neurogenesisGO:00507691650.030
positive regulation of nucleic acid templated transcriptionGO:19035081970.030
macromolecule localizationGO:00330362520.030
Worm
central nervous system developmentGO:00074173110.030
Zebrafish Mouse
organ regenerationGO:00311001010.029
oxoacid metabolic processGO:00434362900.029
positive regulation of transportGO:00510502450.029
negative regulation of cell proliferationGO:00082851190.029
agingGO:00075682410.029
Worm Fly
organelle organizationGO:00069962660.028
Mouse Worm
response to estrogenGO:00436272320.028
Rat
positive regulation of ion transportGO:0043270940.028
neuron deathGO:00709971270.028
positive regulation of developmental processGO:00510942830.028
Worm Fly
divalent inorganic cation transportGO:00725111340.028
cellular response to nitrogen compoundGO:19016992100.028
Rat Fly
cellular metal ion homeostasisGO:00068751720.028
gonad developmentGO:00084061040.028
Fly
tissue morphogenesisGO:0048729220.028
Mouse
negative regulation of rna biosynthetic processGO:19026791180.027
positive regulation of cell proliferationGO:00082842490.027
Fly
positive regulation of nervous system developmentGO:00519621780.026
positive regulation of cell developmentGO:00107201760.026
response to peptide hormoneGO:00434342780.026
Rat Fly
nucleobase containing small molecule metabolic processGO:00550863160.026
negative regulation of multicellular organismal processGO:00512412030.026
Fly
positive regulation of cell differentiationGO:00455972170.026
cell morphogenesisGO:00009021420.026
negative regulation of cell deathGO:00605482290.026
single organism intracellular transportGO:19025821660.026
Worm
calcium mediated signaling using intracellular calcium sourceGO:003558410.025
positive regulation of signal transductionGO:00099671750.025
Human Mouse
response to insulinGO:00328681330.025
Rat Fly
multicellular organismal reproductive processGO:00486092330.025
Zebrafish Worm Fly
cellular cation homeostasisGO:00300031800.025
transmission of nerve impulseGO:0019226420.025
catabolic processGO:00090563510.025
Worm Fly
regulation of phosphorus metabolic processGO:00511743490.025
Human Mouse Rat
response to corticosteroidGO:00319602350.025
Rat
heart developmentGO:0007507720.024
Zebrafish
organ morphogenesisGO:0009887750.024
Zebrafish Mouse
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.024
cellular response to peptideGO:19016531330.024
Rat Fly
neuron developmentGO:00486662860.024
salivary gland developmentGO:000743130.023
organic hydroxy compound metabolic processGO:19016151150.023
neuronal action potentialGO:0019228350.023
heart contractionGO:0060047570.023
response to nutrient levelsGO:00316673700.023
response to woundingGO:00096112540.023
Zebrafish
muscle structure developmentGO:0061061870.022
Fly
negative regulation of programmed cell deathGO:00430691830.022
response to toxic substanceGO:00096361330.022
development of primary sexual characteristicsGO:00451371070.022
Fly
regulation of system processGO:00440572080.022
cell type specific apoptotic processGO:00972851340.022
negative regulation of transportGO:00510511360.022
Rat Worm
potassium ion transportGO:0006813970.022
defense responseGO:00069521940.022
protein complex assemblyGO:00064612630.022
protein complex biogenesisGO:00702712630.022
negative regulation of metanephros developmentGO:007221720.022
nucleotide metabolic processGO:00091172790.022
neuron projection developmentGO:00311752730.022
muscle contractionGO:0006936880.022
regulation of intracellular signal transductionGO:19025312180.021
Human Mouse
brain developmentGO:00074202470.021
Mouse
response to peptideGO:19016522920.021
Rat Fly
regulation of neurogenesisGO:00507672470.021
reproductive structure developmentGO:00486081280.021
Mouse Fly
organonitrogen compound catabolic processGO:19015651790.021
regulation of cellular ketone metabolic processGO:0010565270.021
reproductive system developmentGO:00614581280.020
Mouse Fly
response to extracellular stimulusGO:00099913800.020
membrane organizationGO:0061024940.020
cellular response to peptide hormone stimulusGO:00713751200.020
Rat Fly
secretion by cellGO:00329402480.020
cellular amine metabolic processGO:0044106380.020
regulation of cell morphogenesisGO:0022604770.019
limb morphogenesisGO:003510840.019
organic acid metabolic processGO:00060822920.019
oxidation reduction processGO:00551143040.019
anterior posterior pattern specificationGO:000995210.019
Zebrafish
nucleoside phosphate metabolic processGO:00067532830.019
cytosolic calcium ion homeostasisGO:00514801400.019
ribose phosphate metabolic processGO:00196932350.019
organophosphate metabolic processGO:00196373700.019
carboxylic acid metabolic processGO:00197522890.019
single organism organelle organizationGO:19025891800.019
Mouse
multi organism reproductive processGO:00447032620.019
Zebrafish Worm Fly
axis specificationGO:000979840.019
salivary gland morphogenesisGO:000743510.018
organonitrogen compound biosynthetic processGO:19015661670.018
cellular divalent inorganic cation homeostasisGO:00725031620.018
mechanoreceptor differentiationGO:004249020.018
negative regulation of protein metabolic processGO:00512481140.018
Human Zebrafish Rat
purine ribonucleotide metabolic processGO:00091502270.018
cellular calcium ion homeostasisGO:00068741600.018
sex differentiationGO:00075481130.018
Fly
heart morphogenesisGO:000300730.018
Zebrafish
regulation of anatomical structure sizeGO:00900661350.018
Fly
wound healingGO:00420601220.018
Zebrafish
eye morphogenesisGO:004859240.018
protein localizationGO:00081041910.018
Worm
positive regulation of transcription dna templatedGO:00458931970.018
positive regulation of neuron differentiationGO:00456661260.018
purine nucleotide metabolic processGO:00061632290.018
regulation of cellular component organizationGO:00511283680.018
Mouse Worm Fly
response to estradiolGO:00323551640.017
Rat
regulation of cellular amine metabolic processGO:003323880.017
cardiac muscle contractionGO:0060048270.017
regulation of homeostatic processGO:00328441010.017
gastrulationGO:000736920.017
muscle cell proliferationGO:0033002840.017
bmp signaling pathwayGO:003050940.017
regulation of catalytic activityGO:00507903040.017
Human Zebrafish
cytoskeleton organizationGO:00070101110.017
positive regulation of cell communicationGO:00106472710.017
Human Mouse
head developmentGO:00603222470.017
Mouse
positive regulation of intracellular signal transductionGO:19025331380.017
Human Mouse
camera type eye morphogenesisGO:004859320.017
carbohydrate derivative biosynthetic processGO:19011371240.016
Rat
synaptic growth at neuromuscular junctionGO:005112410.016
response to external biotic stimulusGO:00432072210.016
regulation of cellular amino acid metabolic processGO:000652120.016
cardiac conductionGO:006133720.016
cell morphogenesis involved in neuron differentiationGO:00486671060.016
purine nucleotide biosynthetic processGO:0006164830.016
axonogenesisGO:0007409710.016
protein oligomerizationGO:00512591910.016
response to reactive oxygen speciesGO:00003021200.016
Worm
cell part morphogenesisGO:00329901230.016
regulation of hormone levelsGO:00108171870.016
dna metabolic processGO:0006259960.016
skeletal system developmentGO:0001501410.015
single organism catabolic processGO:00447122830.015
Worm
regulation of cell morphogenesis involved in differentiationGO:0010769720.015
regulation of neuron differentiationGO:00456642080.015
b cell differentiationGO:003018320.015
cell migrationGO:00164771970.015
Human Zebrafish
neurological system processGO:00508772190.015
cellular response to hormone stimulusGO:00328702470.015
Rat Fly
hormone secretionGO:00468791150.015
cellular macromolecular complex assemblyGO:0034622580.015
negative regulation of phosphorus metabolic processGO:0010563800.015
Human Mouse Rat
regulation of muscle system processGO:0090257790.015
ensheathment of neuronsGO:0007272400.015
cellular ion homeostasisGO:00068731840.015
regulation of developmental growthGO:0048638450.015
Worm Fly
cell projection organizationGO:00300303020.015
enzyme linked receptor protein signaling pathwayGO:00071671160.015
Human Zebrafish Rat Fly
proteolysisGO:00065081750.015
Zebrafish
positive regulation of cellular biosynthetic processGO:00313282950.015
protein phosphorylationGO:00064683450.015
Human Mouse Rat Fly
gliogenesisGO:0042063930.014
response to hydrogen peroxideGO:0042542890.014
amine metabolic processGO:0009308380.014
cellular potassium ion transportGO:0071804720.014
myelinationGO:0042552390.014
cellular nitrogen compound catabolic processGO:00442701630.014
cellular response to extracellular stimulusGO:0031668730.014
Worm
response to retinoic acidGO:0032526630.014
localization of cellGO:00516742020.014
Human Zebrafish
intracellular transportGO:00469071850.014
Worm
cellular response to lipidGO:00713962010.014
response to monosaccharideGO:00342841590.014
Rat
cellular amino acid metabolic processGO:00065201070.014
cell communication involved in cardiac conductionGO:008606520.014
purine containing compound metabolic processGO:00725212530.014
regulation of nucleotide metabolic processGO:00061401170.014
multicellular organismal signalingGO:0035637440.014
cellular catabolic processGO:00442482950.014
Worm Fly
female pregnancyGO:00075651220.014
glucose homeostasisGO:0042593750.014
Rat
mitotic spindle organizationGO:000705220.014
heart processGO:0003015570.014
epiboly involved in wound healingGO:009050520.014
regulation of canonical wnt signaling pathwayGO:006082840.014
regulation of cell developmentGO:00602842630.014
tube developmentGO:0035295890.014
Zebrafish
cellular ketone metabolic processGO:0042180510.014
axon ensheathmentGO:0008366400.013
cellular response to external stimulusGO:00714961180.013
Worm
neuron projection morphogenesisGO:00488121220.013
camera type eye developmentGO:0043010480.013
Zebrafish
muscle tissue developmentGO:0060537580.013
regulation of hormone secretionGO:00468831060.013
carbohydrate metabolic processGO:00059751300.013
Fly
spindle organizationGO:000705120.013
nucleoside phosphate biosynthetic processGO:19012931020.013
positive regulation of protein metabolic processGO:00512471780.013
Human Rat
bone developmentGO:0060348250.013
nitrogen compound transportGO:00717052290.013
negative regulation of signalingGO:00230571570.013
Human Mouse
palate developmentGO:006002120.013
inner ear receptor cell differentiationGO:006011320.013
striated muscle tissue developmentGO:0014706580.013
hair cell differentiationGO:003531520.013
response to biotic stimulusGO:00096072260.013
regulation of smooth muscle cell proliferationGO:0048660750.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
organic substance catabolic processGO:19015753160.013
response to hexoseGO:00097461440.013
Rat
positive regulation of catalytic activityGO:00430851840.013
Human
response to transition metal nanoparticleGO:19902671220.013
Rat
regulation of anatomical structure morphogenesisGO:00226031410.013
ribonucleotide biosynthetic processGO:0009260850.013
appendage morphogenesisGO:003510740.013
purine ribonucleoside metabolic processGO:00461281680.013
muscle organ developmentGO:0007517500.012
cell adhesionGO:00071551100.012
locomotionGO:00400112370.012
Human Zebrafish Worm Fly
regulation of secretion by cellGO:19035302080.012
regulation of hydrolase activityGO:00513361430.012
Zebrafish
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
positive regulation of molecular functionGO:00440932300.012
Human
renal system developmentGO:0072001670.012
chromosome segregationGO:000705920.012
biological adhesionGO:00226101100.012
establishment of tissue polarityGO:000716420.012
cellular component movementGO:00069282480.012
Human Zebrafish Fly
cell motilityGO:00488702020.012
Human Zebrafish
embryonic pattern specificationGO:000988010.012
urogenital system developmentGO:0001655780.012
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.012
Human Zebrafish Rat Fly
immunoglobulin secretionGO:004830510.012
striated muscle contractionGO:0006941440.012
anion transmembrane transportGO:0098656770.012
response to glucoseGO:00097491360.012
Rat
ribonucleotide metabolic processGO:00092592310.012
response to other organismGO:00517072200.012
cardiac muscle cell contractionGO:0086003100.012
positive regulation of response to stimulusGO:00485842850.012
Human Mouse
membrane repolarizationGO:008600910.012
regulation of calcium ion transportGO:0051924770.012
regulation of immunoglobulin secretionGO:005102310.012
response to bacteriumGO:00096172000.012
regulation of neuron projection developmentGO:00109751610.011
response to oxidative stressGO:00069791860.011
Worm Fly
potassium ion transmembrane transportGO:0071805710.011
peptide secretionGO:0002790860.011
response to calcium ionGO:0051592590.011
cell cycle processGO:0022402570.011
nucleotide catabolic processGO:00091661390.011
mesoderm developmentGO:000749820.011
regulation of phosphate metabolic processGO:00192203490.011
Human Mouse Rat
single organism behaviorGO:00447081300.011
Fly
cytoplasmic transportGO:00164821150.011
Worm
cellular protein complex assemblyGO:0043623440.011
regulation of stem cell differentiationGO:200073620.011
kidney developmentGO:0001822670.011
amino acid transmembrane transportGO:0003333330.011
establishment of protein localizationGO:00451841410.011
Worm
nucleoside phosphate catabolic processGO:19012921400.011
positive regulation of phosphorus metabolic processGO:00105622620.011
Human Mouse Rat
response to tumor necrosis factorGO:0034612560.011
Rat
actin filament based processGO:0030029860.011
positive regulation of growthGO:0045927550.011
Worm Fly
positive regulation of cellular amine metabolic processGO:003324030.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
nucleotide biosynthetic processGO:0009165980.011
developmental maturationGO:0021700250.011
Fly
regulation of ion transmembrane transportGO:00347651210.011
hematopoietic progenitor cell differentiationGO:000224420.011
kidney mesenchyme developmentGO:007207420.011
cytokine mediated signaling pathwayGO:0019221430.011
positive regulation of cell growthGO:0030307440.011
Fly
neural crest cell migrationGO:000175510.011
regulation of response to stressGO:00801341260.010
Human Worm
cofactor metabolic processGO:0051186950.010
cellular response to acid chemicalGO:0071229750.010
regulation of blood circulationGO:19035221100.010
cardiac chamber developmentGO:000320510.010
positive regulation of secretion by cellGO:19035321280.010
heterocycle catabolic processGO:00467001670.010
response to campGO:0051591910.010
cellular response to cytokine stimulusGO:00713451270.010
regulation of purine nucleotide metabolic processGO:19005421150.010
retina morphogenesis in camera type eyeGO:006004210.010
peptidyl amino acid modificationGO:00181931260.010
Human Mouse Rat Fly
cell cell signaling involved in cell fate commitmentGO:004516820.010
lung developmentGO:0030324430.010
gamete generationGO:00072761240.010
Zebrafish Worm Fly

Igf1r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
urinary system diseaseDOID:1800.023
nervous system diseaseDOID:86300.023
sensory system diseaseDOID:005015500.023
musculoskeletal system diseaseDOID:1700.021
cardiovascular system diseaseDOID:128700.012
eye and adnexa diseaseDOID:149200.010