IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Xpot

exportin, tRNA (nuclear export receptor for tRNAs)

Entrez: 314879
RGD: 1305562
Ensembl: ENSRNOG00000007088
UniProtKB: D3ZZ62

Process Predictions
Disease Predictions

Xpot biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
carboxylic acid metabolic process	GO:0019752	289	0.075
glycerolipid metabolic process	GO:0046486	67	0.059
organic acid metabolic process	GO:0006082	292	0.059
organophosphate biosynthetic process	GO:0090407	143	0.054
response to other organism	GO:0051707	220	0.050
organonitrogen compound biosynthetic process	GO:1901566	167	0.048
cellular lipid metabolic process	GO:0044255	208	0.047
homeostatic process	GO:0042592	331	0.046
acylglycerol metabolic process	GO:0006639	21	0.046
lipid biosynthetic process	GO:0008610	128	0.043
neutral lipid metabolic process	GO:0006638	21	0.043
fatty acid metabolic process	GO:0006631	99	0.042
regulation of multicellular organismal development	GO:2000026	376	0.040
monocarboxylic acid metabolic process	GO:0032787	152	0.040
lipid metabolic process	GO:0006629	283	0.040
small molecule biosynthetic process	GO:0044283	124	0.039
nucleoside phosphate metabolic process	GO:0006753	283	0.038
cellular response to stress	GO:0033554	269	0.032
oxoacid metabolic process	GO:0043436	290	0.031
negative regulation of developmental process	GO:0051093	125	0.029
response to metal ion	GO:0010038	253	0.028
central nervous system neuron axonogenesis	GO:0021955	1	0.028
single organism biosynthetic process	GO:0044711	342	0.028
cellular amine metabolic process	GO:0044106	38	0.028
response to toxic substance	GO:0009636	133	0.027
defense response	GO:0006952	194	0.026
amine metabolic process	GO:0009308	38	0.025
nucleobase containing small molecule metabolic process	GO:0055086	316	0.025
negative regulation of multicellular organismal process	GO:0051241	203	0.024
positive regulation of multicellular organismal process	GO:0051240	387	0.022
regulation of phosphorus metabolic process	GO:0051174	349	0.021
phosphatidylinositol dephosphorylation	GO:0046856	4	0.021
long chain fatty acid metabolic process	GO:0001676	32	0.020
response to extracellular stimulus	GO:0009991	380	0.020
triglyceride metabolic process	GO:0006641	21	0.019
chemical homeostasis	GO:0048878	292	0.019
regulation of phosphorylation	GO:0042325	248	0.019
response to nutrient levels	GO:0031667	370	0.018
carbohydrate derivative metabolic process	GO:1901135	346	0.018
regulation of protein metabolic process	GO:0051246	289	0.018
response to cytokine	GO:0034097	215	0.018
organophosphate metabolic process	GO:0019637	370	0.018
carboxylic acid transport	GO:0046942	115	0.018
carboxylic acid biosynthetic process	GO:0046394	83	0.018
cellular response to cytokine stimulus	GO:0071345	127	0.018
cellular amino acid metabolic process	GO:0006520	107	0.018
regulation of protein modification process	GO:0031399	194	0.017
fatty acid biosynthetic process	GO:0006633	33	0.017
response to biotic stimulus	GO:0009607	226	0.017
central nervous system development	GO:0007417	311	0.017
cell motility	GO:0048870	202	0.017
regulation of secretion	GO:0051046	224	0.016
negative regulation of cell death	GO:0060548	229	0.016
lipid localization	GO:0010876	62	0.016
programmed cell death	GO:0012501	392	0.016
cellular homeostasis	GO:0019725	252	0.016
nucleoside phosphate biosynthetic process	GO:1901293	102	0.016
regulation of phosphatidylinositol dephosphorylation	GO:0060304	1	0.015
regulation of cellular component organization	GO:0051128	368	0.015
bmp signaling pathway	GO:0030509	4	0.015
regulation of phosphate metabolic process	GO:0019220	349	0.015
organic acid transport	GO:0015849	116	0.015
nitrogen compound transport	GO:0071705	229	0.014
regulation of cell migration	GO:0030334	128	0.014
response to inorganic substance	GO:0010035	377	0.014
monocarboxylic acid biosynthetic process	GO:0072330	48	0.014
regulation of apoptotic process	GO:0042981	335	0.014
regulation of hormone levels	GO:0010817	187	0.014
glycosyl compound metabolic process	GO:1901657	182	0.014
intracellular signal transduction	GO:0035556	314	0.014
long chain fatty acid transport	GO:0015909	14	0.013
carbohydrate metabolic process	GO:0005975	130	0.013
purine containing compound metabolic process	GO:0072521	253	0.013
cellular response to growth factor stimulus	GO:0071363	162	0.013
organic acid biosynthetic process	GO:0016053	83	0.013
regulation of response to stress	GO:0080134	126	0.013
ribonucleoside metabolic process	GO:0009119	174	0.013
pyrimidine nucleotide metabolic process	GO:0006220	9	0.013
response to nutrient	GO:0007584	248	0.013
anion transport	GO:0006820	178	0.013
cellular macromolecular complex assembly	GO:0034622	58	0.013
macromolecular complex assembly	GO:0065003	273	0.013
protein complex subunit organization	GO:0071822	302	0.013
carbohydrate derivative biosynthetic process	GO:1901137	124	0.012
regulation of cell differentiation	GO:0045595	320	0.012
transmembrane transport	GO:0055085	412	0.012
nucleoside metabolic process	GO:0009116	179	0.012
response to interleukin 15	GO:0070672	4	0.012
macromolecular complex subunit organization	GO:0043933	339	0.012
response to growth factor	GO:0070848	189	0.012
cellular response to hexose stimulus	GO:0071331	65	0.012
nucleotide metabolic process	GO:0009117	279	0.012
regulation of neuron differentiation	GO:0045664	208	0.012
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.012
cell cell signaling	GO:0007267	335	0.012
stress activated mapk cascade	GO:0051403	35	0.012
carbohydrate homeostasis	GO:0033500	75	0.012
protein phosphorylation	GO:0006468	345	0.012
regulation of catalytic activity	GO:0050790	304	0.012
regulation of cellular amino acid metabolic process	GO:0006521	2	0.012
brain development	GO:0007420	247	0.012
positive regulation of secretion by cell	GO:1903532	128	0.012
ribose phosphate metabolic process	GO:0019693	235	0.011
chromosome segregation	GO:0007059	2	0.011
regulation of bmp signaling pathway	GO:0030510	2	0.011
regulation of organic acid transport	GO:0032890	35	0.011
negative regulation of programmed cell death	GO:0043069	183	0.011
response to vitamin	GO:0033273	131	0.011
response to carbohydrate	GO:0009743	183	0.011
regulation of cellular response to stress	GO:0080135	49	0.011
cytokine biosynthetic process	GO:0042089	3	0.011
hormone secretion	GO:0046879	115	0.011
positive regulation of biosynthetic process	GO:0009891	319	0.011
negative regulation of organic acid transport	GO:0032891	14	0.011
stress activated protein kinase signaling cascade	GO:0031098	37	0.011
response to external biotic stimulus	GO:0043207	221	0.011
positive regulation of cell projection organization	GO:0031346	111	0.011
positive regulation of cellular component organization	GO:0051130	200	0.010
tissue development	GO:0009888	252	0.010
vesicle mediated transport	GO:0016192	181	0.010
regulation of cell motility	GO:2000145	131	0.010

Xpot disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.049
disease of anatomical entity	DOID:7	0.049
neuromuscular disease	DOID:440	0.043
charcot marie tooth disease	DOID:10595	0.043
charcot marie tooth disease type 2	DOID:0050539	0.043
neuropathy	DOID:870	0.043
organ system cancer	DOID:0050686	0.026
cancer	DOID:162	0.026
disease of cellular proliferation	DOID:14566	0.026
central nervous system disease	DOID:331	0.023
disease of metabolism	DOID:0014667	0.010

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