Rattus norvegicus

36 known processes

Pgam2

phosphoglycerate mutase 2 (muscle)

(Aliases: PGAM-M,D14Mgh1,Pgmut)

Pgam2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle system processGO:00030121150.523
Human
heart contractionGO:0060047570.332
homeostatic processGO:00425923310.287
Rat
oxoacid metabolic processGO:00434362900.274
Human Yeast Mouse
twitch skeletal muscle contractionGO:001472130.257
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.237
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.217
ventricular cardiac muscle cell action potentialGO:008600520.203
organic acid metabolic processGO:00060822920.194
Human Yeast Mouse
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.183
regulation of system processGO:00440572080.175
response to metal ionGO:00100382530.169
response to oxygen levelsGO:00704822650.167
divalent metal ion transportGO:00708381320.166
response to hypoxiaGO:00016662310.163
organic substance catabolic processGO:19015753160.157
Human Yeast Mouse
carboxylic acid metabolic processGO:00197522890.154
Human Yeast Mouse
regenerationGO:00310991630.152
cellular modified amino acid biosynthetic processGO:0042398180.152
cardiac muscle tissue morphogenesisGO:005500810.151
cellular response to endogenous stimulusGO:00714953770.150
muscle contractionGO:0006936880.149
Human
striated muscle tissue developmentGO:0014706580.145
organophosphate metabolic processGO:00196373700.137
single organism biosynthetic processGO:00447113420.116
striated muscle contractionGO:0006941440.114
Human
cardiac muscle contractionGO:0060048270.114
cellular response to hormone stimulusGO:00328702470.111
purine nucleotide metabolic processGO:00061632290.106
response to decreased oxygen levelsGO:00362932370.103
cation homeostasisGO:00550801950.102
cellular amino acid metabolic processGO:00065201070.100
response to inorganic substanceGO:00100353770.098
response to purine containing compoundGO:00140741260.095
slow twitch skeletal muscle fiber contractionGO:003144420.089
regulation of ion transportGO:00432692450.088
purine ribonucleoside monophosphate metabolic processGO:0009167840.087
single organism carbohydrate catabolic processGO:0044724400.087
Human Yeast Mouse
carbohydrate derivative metabolic processGO:19011353460.086
cardiac ventricle developmentGO:000323110.085
cardiac chamber developmentGO:000320510.084
oxidation reduction processGO:00551143040.083
endoplasmic reticulum to cytosol transportGO:190351340.083
actin filament based movementGO:0030048160.081
cardiac myofibril assemblyGO:005500310.081
carbohydrate catabolic processGO:0016052400.080
Human Yeast Mouse
muscle filament slidingGO:003004920.077
nucleotide metabolic processGO:00091172790.076
nucleobase containing small molecule metabolic processGO:00550863160.074
negative regulation of cell growth involved in cardiac muscle cell developmentGO:006105210.074
ion homeostasisGO:00508012120.072
nucleobase containing compound catabolic processGO:00346551520.070
metal ion transportGO:00300012890.070
voluntary skeletal muscle contractionGO:000301030.070
chemical homeostasisGO:00488782920.070
cellular ion homeostasisGO:00068731840.069
divalent inorganic cation homeostasisGO:00725071650.066
tissue developmentGO:00098882520.066
single organism intracellular transportGO:19025821660.066
cation transportGO:00068123820.066
growthGO:00400071650.063
ribonucleoside triphosphate metabolic processGO:00091991410.062
muscle organ morphogenesisGO:004864410.062
single organism catabolic processGO:00447122830.060
Human Yeast Mouse
negative regulation of neuron differentiationGO:0045665620.059
divalent inorganic cation transportGO:00725111340.059
myosin filament assemblyGO:003103410.057
organophosphate biosynthetic processGO:00904071430.057
purine ribonucleoside monophosphate catabolic processGO:0009169550.056
metal ion homeostasisGO:00550651860.055
response to campGO:0051591910.054
calcium ion homeostasisGO:00550741620.054
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.053
muscle tissue developmentGO:0060537580.052
heart morphogenesisGO:000300730.052
inorganic cation transmembrane transportGO:00986622020.051
cellular modified amino acid metabolic processGO:0006575610.051
regulation of muscle contractionGO:0006937530.050
cellular chemical homeostasisGO:00550822470.049
muscle cell differentiationGO:0042692520.049
Fly
aromatic compound catabolic processGO:00194391680.049
cellular component morphogenesisGO:00329891550.046
purine nucleoside monophosphate metabolic processGO:0009126840.045
positive regulation of multicellular organismal processGO:00512403870.045
reproductive system developmentGO:00614581280.045
protein complex subunit organizationGO:00718223020.045
hexose metabolic processGO:0019318580.044
carbohydrate metabolic processGO:00059751300.044
myosin filament organizationGO:003103320.042
potassium ion transmembrane transportGO:0071805710.042
sequestering of metal ionGO:005123890.042
cytosolic calcium ion homeostasisGO:00514801400.041
amine metabolic processGO:0009308380.041
cardiac muscle cell contractionGO:0086003100.040
regulation of cellular component organizationGO:00511283680.040
cell projection organizationGO:00300303020.039
cellular calcium ion homeostasisGO:00068741600.038
catabolic processGO:00090563510.038
Human Yeast Mouse
regulation of muscle system processGO:0090257790.038
cellular homeostasisGO:00197252520.038
muscle organ developmentGO:0007517500.038
maintenance of locationGO:0051235170.038
regulation of ion homeostasisGO:2000021630.037
ion transmembrane transportGO:00342203650.037
glycosyl compound metabolic processGO:19016571820.037
cellular cation homeostasisGO:00300031800.037
response to nutrient levelsGO:00316673700.036
reproductive structure developmentGO:00486081280.036
regulation of cell differentiationGO:00455953200.036
sarcoplasmic reticulum calcium ion transportGO:007029680.036
heart processGO:0003015570.035
blood circulationGO:00080151830.035
transmembrane transportGO:00550854120.035
cellular metal ion homeostasisGO:00068751720.035
response to acid chemicalGO:00011012220.035
ribonucleoside triphosphate catabolic processGO:00092031220.035
cellular response to stressGO:00335542690.035
response to electrical stimulusGO:0051602560.034
response to extracellular stimulusGO:00099913800.034
cellular amine metabolic processGO:0044106380.034
response to corticosteroidGO:00319602350.034
purine ribonucleoside metabolic processGO:00461281680.033
negative regulation of programmed cell deathGO:00430691830.033
negative regulation of organ growthGO:004662130.033
monovalent inorganic cation transportGO:00156721720.033
purine nucleoside monophosphate catabolic processGO:0009128550.032
cellular component biogenesisGO:00440853680.032
nucleoside monophosphate metabolic processGO:0009123930.032
proteolysisGO:00065081750.032
negative regulation of cardiac muscle tissue developmentGO:005502630.031
ribonucleoside metabolic processGO:00091191740.031
regulation of multicellular organismal developmentGO:20000263760.030
monocarboxylic acid metabolic processGO:00327871520.030
Human Yeast Mouse
macromolecular complex assemblyGO:00650032730.030
cellular response to fluid shear stressGO:007149840.030
nucleoside phosphate metabolic processGO:00067532830.030
carboxylic acid biosynthetic processGO:0046394830.030
calcium ion transportGO:00068161310.030
ribose phosphate metabolic processGO:00196932350.030
heterocycle catabolic processGO:00467001670.029
positive regulation of rna biosynthetic processGO:19026801970.029
positive regulation of potassium ion transmembrane transportGO:190138140.029
negative regulation of signal transductionGO:0009968830.029
actin mediated cell contractionGO:0070252120.028
response to organophosphorusGO:00466831020.028
response to insulinGO:00328681330.028
urogenital system developmentGO:0001655780.028
apoptotic processGO:00069153810.028
agingGO:00075682410.027
response to oxidative stressGO:00069791860.027
central nervous system developmentGO:00074173110.027
positive regulation of developmental processGO:00510942830.027
glycerolipid metabolic processGO:0046486670.027
sequestering of calcium ionGO:005120880.027
response to glucocorticoidGO:00513842230.027
regulation of rna metabolic processGO:00512523910.026
cellular component assembly involved in morphogenesisGO:0010927170.026
intracellular signal transductionGO:00355563140.026
negative regulation of transportGO:00510511360.026
positive regulation of cell differentiationGO:00455972170.026
regulation of cellular localizationGO:00603412630.026
regulation of heart contractionGO:0008016480.025
ventricular cardiac muscle cell developmentGO:005501520.025
regulation of cardiac muscle contractionGO:0055117170.025
regulation of rna biosynthetic processGO:20011413810.025
nucleoside metabolic processGO:00091161790.025
cation transmembrane transportGO:00986552630.025
developmental growthGO:00485891000.025
response to peptide hormoneGO:00434342780.024
purine nucleoside metabolic processGO:00422781690.024
organonitrogen compound biosynthetic processGO:19015661670.024
cellular amino acid biosynthetic processGO:0008652320.024
cardiac muscle cell action potential involved in contractionGO:008600220.024
neuron differentiationGO:00301823680.024
negative regulation of signalingGO:00230571570.023
polysaccharide metabolic processGO:0005976250.023
positive regulation of peptide hormone secretionGO:0090277500.023
regulation of peptide hormone secretionGO:0090276800.023
nucleoside triphosphate metabolic processGO:00091411440.023
circulatory system processGO:00030131830.023
negative regulation of ion transportGO:0043271510.023
negative regulation of apoptotic processGO:00430661810.023
brain developmentGO:00074202470.022
multicellular organism reproductionGO:00325042330.022
protein complex assemblyGO:00064612630.022
heart developmentGO:0007507720.022
ribonucleoside monophosphate catabolic processGO:0009158550.022
ribonucleoside monophosphate metabolic processGO:0009161880.022
response to heatGO:0009408600.022
nucleoside catabolic processGO:00091641260.022
actin cytoskeleton organizationGO:0030036730.022
purine ribonucleotide metabolic processGO:00091502270.022
cellular divalent inorganic cation homeostasisGO:00725031620.022
lipid metabolic processGO:00066292830.022
head developmentGO:00603222470.022
peptide transportGO:0015833970.022
purine containing compound metabolic processGO:00725212530.022
glycosyl compound catabolic processGO:19016581260.022
cellular component assemblyGO:00226073600.021
response to electrical stimulus involved in regulation of muscle adaptationGO:001487840.021
kidney developmentGO:0001822670.021
regulation of response to stressGO:00801341260.021
regulation of organ growthGO:0046620130.021
cellular response to oxygen containing compoundGO:19017013860.021
regulation of chromosome segregationGO:005198310.021
cellular response to insulin stimulusGO:0032869810.021
cellular ketone metabolic processGO:0042180510.020
single organism organelle organizationGO:19025891800.020
establishment of tissue polarityGO:000716420.020
response to estrogenGO:00436272320.020
negative regulation of muscle hypertrophyGO:001474130.020
organelle organizationGO:00069962660.020
positive regulation of cell proliferationGO:00082842490.020
response to estradiolGO:00323551640.020
cytoskeleton organizationGO:00070101110.020
regulation of cellular amine metabolic processGO:003323880.020
protein tetramerizationGO:0051262380.020
proteolysis involved in cellular protein catabolic processGO:0051603190.020
cofactor metabolic processGO:0051186950.020
enzyme linked receptor protein signaling pathwayGO:00071671160.020
response to woundingGO:00096112540.019
cellular response to abiotic stimulusGO:0071214850.019
cellular response to organonitrogen compoundGO:00714171970.019
circulatory system developmentGO:00723591340.019
single organism reproductive processGO:00447022970.019
multi organism reproductive processGO:00447032620.019
atp metabolic processGO:0046034720.019
lipid transportGO:0006869610.019
cardiocyte differentiationGO:0035051220.019
single organism carbohydrate metabolic processGO:00447231180.019
anatomical structure formation involved in morphogenesisGO:0048646830.018
Fly
negative regulation of metabolic processGO:00098923310.018
developmental process involved in reproductionGO:00030061590.018
multi multicellular organism processGO:00447061380.018
action potentialGO:0001508540.018
reproductionGO:00000032450.018
cellular response to peptide hormone stimulusGO:00713751200.018
organic cyclic compound catabolic processGO:19013611750.018
skeletal muscle tissue regenerationGO:0043403100.018
regulation of release of sequestered calcium ion into cytosolGO:0051279180.018
erythrocyte differentiationGO:003021810.018
Rat
ribonucleotide metabolic processGO:00092592310.018
purine nucleoside triphosphate metabolic processGO:00091441410.017
inner ear receptor cell differentiationGO:006011320.017
cardiac muscle cell developmentGO:0055013160.017
macromolecule catabolic processGO:0009057580.017
purine ribonucleoside triphosphate metabolic processGO:00092051400.017
muscle structure developmentGO:0061061870.017
Fly
response to hexoseGO:00097461440.017
negative regulation of cell deathGO:00605482290.017
cardiovascular system developmentGO:00723581340.017
multicellular organismal signalingGO:0035637440.017
gonad developmentGO:00084061040.017
purine nucleoside triphosphate catabolic processGO:00091461220.017
organophosphate catabolic processGO:00464341480.017
negative regulation of cardiac muscle tissue growthGO:005502230.017
regulation of cell developmentGO:00602842630.017
negative regulation of sequestering of calcium ionGO:0051283250.017
negative regulation of cell differentiationGO:0045596990.017
metaphase anaphase transition of mitotic cell cycleGO:000709110.017
ribonucleoside catabolic processGO:00424541260.017
response to activityGO:0014823730.017
cellular macromolecule localizationGO:00707271220.016
generation of precursor metabolites and energyGO:0006091620.016
Human Yeast Mouse
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
purine ribonucleotide catabolic processGO:00091541360.016
regulation of secretion by cellGO:19035302080.016
regulation of stem cell differentiationGO:200073620.016
regulation of cellular amino acid metabolic processGO:000652120.016
cellular protein localizationGO:00346131220.016
nucleoside phosphate catabolic processGO:19012921400.016
proline transportGO:001582430.016
response to amino acidGO:0043200750.016
wound healingGO:00420601220.016
regulation of neuron projection developmentGO:00109751610.016
negative regulation of transporter activityGO:0032410130.016
regulation of cell projection organizationGO:00313441750.016
neuron projection morphogenesisGO:00488121220.016
response to peptideGO:19016522920.016
regulation of molecular functionGO:00650093980.015
organic acid biosynthetic processGO:0016053830.015
regulation of neuron differentiationGO:00456642080.015
regulation of striated muscle contractionGO:0006942210.015
multicellular organismal reproductive processGO:00486092330.015
negative regulation of ion transmembrane transporter activityGO:0032413120.015
protein complex biogenesisGO:00702712630.015
small molecule biosynthetic processGO:00442831240.015
sulfur compound metabolic processGO:0006790700.015
purine ribonucleoside monophosphate biosynthetic processGO:0009168200.015
organic hydroxy compound metabolic processGO:19016151150.015
glycerol transportGO:001579320.015
calcium ion transmembrane transportGO:0070588700.015
secretionGO:00469033070.015
regulation of skeletal muscle tissue regenerationGO:004341620.015
cellular glucan metabolic processGO:0006073230.015
tissue regenerationGO:0042246360.015
cellular nitrogen compound catabolic processGO:00442701630.015
nucleobase biosynthetic processGO:004611220.015
regulation of blood circulationGO:19035221100.015
reproductive processGO:00224143720.015
actin filament based processGO:0030029860.015
negative regulation of mitotic cell cycle phase transitionGO:190199130.015
intracellular transportGO:00469071850.015
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.014
negative regulation of epithelial cell proliferationGO:0050680160.014
cellular protein complex assemblyGO:0043623440.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
regulation of cell proliferationGO:00421273590.014
positive regulation of receptor activityGO:200027340.014
cardiac cell developmentGO:0055006160.014
striated muscle cell developmentGO:0055002260.014
glycogen metabolic processGO:0005977230.014
negative regulation of cell developmentGO:0010721820.014
response to reactive oxygen speciesGO:00003021200.014
amide transportGO:00428861050.014
negative regulation of cell proliferationGO:00082851190.014
transcription dna templatedGO:00063513770.014
rna metabolic processGO:00160704060.014
potassium ion transportGO:0006813970.014
negative regulation of nervous system developmentGO:0051961790.013
rna biosynthetic processGO:00327743800.013
regulation of programmed cell deathGO:00430673410.013
inorganic ion transmembrane transportGO:00986602290.013
cell cycle checkpointGO:000007520.013
cellular response to nitrogen compoundGO:19016992100.013
purine containing compound catabolic processGO:00725231380.013
regulation of apoptotic processGO:00429813350.013
response to ketoneGO:19016541820.013
regulation of anatomical structure sizeGO:00900661350.013
mitotic sister chromatid separationGO:005130610.013
purine ribonucleoside catabolic processGO:00461301240.013
negative regulation of heart growthGO:006111730.013
tissue morphogenesisGO:0048729220.013
regulation of mitotic sister chromatid segregationGO:003304710.013
ribose phosphate biosynthetic processGO:0046390870.013
regulation of cellular ketone metabolic processGO:0010565270.013
phospholipid biosynthetic processGO:0008654290.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
male gamete generationGO:0048232990.013
regulation of establishment of planar polarityGO:009017520.013
sexual reproductionGO:00199531480.012
regulation of notch signaling pathwayGO:000859330.012
receptor mediated endocytosisGO:0006898420.012
chylomicron remodelingGO:003437110.012
neuron developmentGO:00486662860.012
negative regulation of release of sequestered calcium ion into cytosolGO:005128040.012
cell projection morphogenesisGO:00488581230.012
glucan metabolic processGO:0044042230.012
renal system developmentGO:0072001670.012
sex differentiationGO:00075481130.012
defense responseGO:00069521940.012
peptide secretionGO:0002790860.012
positive regulation of blood circulationGO:1903524650.012
nucleoside monophosphate catabolic processGO:0009125560.012
regulation of nervous system developmentGO:00519602640.012
negative regulation of molecular functionGO:00440921330.012
regulation of epithelial cell proliferationGO:0050678490.012
regulation of anatomical structure morphogenesisGO:00226031410.012
regulation of endocytosisGO:0030100420.012
microtubule cytoskeleton organizationGO:0000226250.012
protein homotetramerizationGO:0051289250.012
nucleotide catabolic processGO:00091661390.011
purine nucleoside catabolic processGO:00061521240.011
regulation of metal ion transportGO:00109591180.011
neuronal action potentialGO:0019228350.011
insulin like growth factor receptor signaling pathwayGO:004800930.011
regulation of transmembrane transporter activityGO:0022898490.011
dna metabolic processGO:0006259960.011
acyl coa metabolic processGO:0006637280.011
positive regulation of rna metabolic processGO:00512542030.011
response to muscle activity involved in regulation of muscle adaptationGO:001487320.011
chromosome segregationGO:000705920.011
cellular potassium ion transportGO:0071804720.011
regulation of catalytic activityGO:00507903040.011
cytosolic calcium ion transportGO:0060401390.011
positive regulation of biosynthetic processGO:00098913190.011
pigment biosynthetic processGO:004614840.011
lipid biosynthetic processGO:00086101280.011
regulation of transporter activityGO:0032409500.010
negative regulation of neurogenesisGO:0050768780.010
regulation of neurogenesisGO:00507672470.010
response to ethanolGO:00454711620.010
myofibril assemblyGO:003023960.010
regulation of mitotic sister chromatid separationGO:001096510.010
programmed cell deathGO:00125013920.010
negative regulation of cell communicationGO:00106481580.010
nucleoside monophosphate biosynthetic processGO:0009124280.010
regulation of catabolic processGO:00098941130.010
mechanoreceptor differentiationGO:004249020.010
positive regulation of nitrogen compound metabolic processGO:00511733340.010
cold acclimationGO:000963110.010
positive regulation of cellular amine metabolic processGO:003324030.010
appendage morphogenesisGO:003510740.010
negative regulation of multicellular organismal processGO:00512412030.010
cellular response to peptideGO:19016531330.010

Pgam2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscular diseaseDOID:008000000.590
muscle tissue diseaseDOID:6600.590
musculoskeletal system diseaseDOID:1700.590
disease of anatomical entityDOID:700.590
heart diseaseDOID:11400.547
intrinsic cardiomyopathyDOID:006003600.547
cardiovascular system diseaseDOID:128700.547
myopathyDOID:42300.547
cardiomyopathyDOID:005070000.547
dilated cardiomyopathyDOID:1293000.218
long qt syndromeDOID:284300.142
congenital heart diseaseDOID:168200.113
heart septal defectDOID:168100.113
hypertrophic cardiomyopathyDOID:1198400.041
disease of metabolismDOID:001466700.035
heart conduction diseaseDOID:1027300.030
muscular dystrophyDOID:988400.021
renal tubular transport diseaseDOID:44700.019
kidney diseaseDOID:55700.019
urinary system diseaseDOID:1800.019
acquired metabolic diseaseDOID:006015800.011