Rattus norvegicus

20 known processes

Tph1

tryptophan hydroxylase 1

(Aliases: Tph)

Tph1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to hormone stimulusGO:00328702470.239
response to extracellular stimulusGO:00099913800.130
Rat
cellular response to organonitrogen compoundGO:00714171970.101
Rat
cellular response to organic cyclic compoundGO:00714072020.097
Rat
response to nutrientGO:00075842480.096
cellular response to steroid hormone stimulusGO:0071383930.091
cellular response to lipidGO:00713962010.089
regulation of molecular functionGO:00650093980.088
lipid metabolic processGO:00066292830.085
Rat
response to nutrient levelsGO:00316673700.079
Rat
response to peptideGO:19016522920.076
Rat
cellular response to endogenous stimulusGO:00714953770.075
Rat
regulation of hormone levelsGO:00108171870.075
anatomical structure morphogenesisGO:00096532980.074
cellular response to oxygen containing compoundGO:19017013860.073
Rat
response to peptide hormoneGO:00434342780.072
Rat
cellular response to peptide hormone stimulusGO:00713751200.071
regulation of secretion by cellGO:19035302080.069
carboxylic acid metabolic processGO:00197522890.067
Rat
protein complex biogenesisGO:00702712630.065
protein phosphorylationGO:00064683450.063
apoptotic processGO:00069153810.063
secretion by cellGO:00329402480.062
homeostatic processGO:00425923310.062
Rat
cellular component assemblyGO:00226073600.061
cellular response to peptideGO:19016531330.060
cellular response to nitrogen compoundGO:19016992100.059
Rat
regulation of apoptotic processGO:00429813350.059
neurological system processGO:00508772190.058
Rat
cellular component biogenesisGO:00440853680.057
cellular homeostasisGO:00197252520.056
Rat
single organism biosynthetic processGO:00447113420.056
Rat
transcription dna templatedGO:00063513770.056
regulation of cellular localizationGO:00603412630.055
response to bacteriumGO:00096172000.054
Rat
response to estradiolGO:00323551640.054
Rat
response to corticosteroidGO:00319602350.053
Rat
response to other organismGO:00517072200.052
Rat
regulation of phosphorus metabolic processGO:00511743490.052
regulation of secretionGO:00510462240.050
regulation of cellular component organizationGO:00511283680.050
ion homeostasisGO:00508012120.049
oxoacid metabolic processGO:00434362900.049
Rat
nucleobase containing small molecule metabolic processGO:00550863160.048
response to external biotic stimulusGO:00432072210.048
Rat
cell projection organizationGO:00300303020.048
secretionGO:00469033070.048
cell cell signalingGO:00072673350.047
Rat
negative regulation of metabolic processGO:00098923310.046
negative regulation of macromolecule metabolic processGO:00106052600.045
cellular response to corticosteroid stimulusGO:0071384690.044
negative regulation of apoptotic processGO:00430661810.044
programmed cell deathGO:00125013920.043
organic acid metabolic processGO:00060822920.043
Rat
regulation of nucleic acid templated transcriptionGO:19035063800.043
negative regulation of cellular metabolic processGO:00313242810.043
positive regulation of nitrogen compound metabolic processGO:00511733340.043
head developmentGO:00603222470.042
Rat
behaviorGO:00076102050.042
Rat
single organism catabolic processGO:00447122830.042
nitrogen compound transportGO:00717052290.041
Rat
protein complex assemblyGO:00064612630.041
regulation of rna metabolic processGO:00512523910.041
response to glucocorticoidGO:00513842230.041
Rat
chemical homeostasisGO:00488782920.041
Rat
regulation of phosphate metabolic processGO:00192203490.040
rhythmic processGO:00485111560.040
cellular metal ion homeostasisGO:00068751720.040
macromolecular complex assemblyGO:00650032730.039
nucleic acid templated transcriptionGO:00976593790.039
single organism intracellular transportGO:19025821660.038
cellular response to growth factor stimulusGO:00713631620.038
Rat
multicellular organism reproductionGO:00325042330.038
regulation of transcription dna templatedGO:00063553740.038
negative regulation of transportGO:00510511360.038
cation homeostasisGO:00550801950.038
regulation of neuron deathGO:19012141150.037
organophosphate metabolic processGO:00196373700.037
regulation of multicellular organismal developmentGO:20000263760.037
regulation of cellular protein metabolic processGO:00322682670.037
response to vitaminGO:00332731310.037
response to growth factorGO:00708481890.036
Rat
response to metal ionGO:00100382530.036
Rat
regulation of catalytic activityGO:00507903040.036
regulation of protein metabolic processGO:00512462890.036
negative regulation of multicellular organismal processGO:00512412030.035
cellular chemical homeostasisGO:00550822470.035
Rat
rna biosynthetic processGO:00327743800.035
response to lipopolysaccharideGO:00324961910.035
Rat
macromolecular complex subunit organizationGO:00439333390.035
cation transportGO:00068123820.035
cellular response to glucocorticoid stimulusGO:0071385680.035
alpha amino acid metabolic processGO:1901605710.035
Rat
divalent inorganic cation homeostasisGO:00725071650.034
neuron differentiationGO:00301823680.034
protein oligomerizationGO:00512591910.033
cellular ion homeostasisGO:00068731840.033
cellular response to alcoholGO:0097306870.033
regulation of neuron differentiationGO:00456642080.033
regulation of phosphorylationGO:00423252480.033
negative regulation of programmed cell deathGO:00430691830.033
protein complex subunit organizationGO:00718223020.033
regulation of homeostatic processGO:00328441010.032
cell morphogenesisGO:00009021420.032
central nervous system developmentGO:00074173110.032
Rat
metal ion transportGO:00300012890.032
regulation of rna biosynthetic processGO:20011413810.032
response to acid chemicalGO:00011012220.031
Rat
regulation of protein phosphorylationGO:00019321830.031
response to amino acidGO:0043200750.031
regulation of cell proliferationGO:00421273590.031
cellular response to stressGO:00335542690.031
single organism reproductive processGO:00447022970.031
organelle organizationGO:00069962660.031
neuron developmentGO:00486662860.031
reproductionGO:00000032450.030
positive regulation of multicellular organismal processGO:00512403870.030
negative regulation of gene expressionGO:00106291990.030
defense responseGO:00069521940.030
multicellular organismal reproductive processGO:00486092330.030
amine metabolic processGO:0009308380.030
intracellular transportGO:00469071850.030
negative regulation of biosynthetic processGO:00098901680.030
cellular ketone metabolic processGO:0042180510.030
cellular cation homeostasisGO:00300031800.029
positive regulation of gene expressionGO:00106282440.029
response to oxidative stressGO:00069791860.028
regulation of cellular amino acid metabolic processGO:000652120.028
estrogen catabolic processGO:000671110.028
response to mechanical stimulusGO:00096121340.028
cellular response to ketoneGO:1901655510.027
negative regulation of cell deathGO:00605482290.027
negative regulation of secretionGO:0051048820.027
neuron projection developmentGO:00311752730.027
positive regulation of phosphate metabolic processGO:00459372620.027
response to estrogenGO:00436272320.027
Rat
response to ketoneGO:19016541820.027
Rat
metal ion homeostasisGO:00550651860.027
response to hexoseGO:00097461440.026
Rat
response to glucoseGO:00097491360.026
Rat
regulation of signal transductionGO:00099663180.026
monocarboxylic acid metabolic processGO:00327871520.026
Rat
positive regulation of catalytic activityGO:00430851840.026
single organism behaviorGO:00447081300.026
cellular response to cytokine stimulusGO:00713451270.026
reproductive processGO:00224143720.026
response to biotic stimulusGO:00096072260.026
Rat
rna metabolic processGO:00160704060.026
negative regulation of nitrogen compound metabolic processGO:00511721610.025
cellular divalent inorganic cation homeostasisGO:00725031620.025
signal releaseGO:00230611450.025
regulation of programmed cell deathGO:00430673410.025
macromolecule localizationGO:00330362520.025
response to molecule of bacterial originGO:00022371940.024
Rat
intracellular signal transductionGO:00355563140.024
negative regulation of cellular biosynthetic processGO:00313271610.024
regenerationGO:00310991630.024
positive regulation of cellular biosynthetic processGO:00313282950.024
response to hypoxiaGO:00016662310.024
Rat
cellular amine metabolic processGO:0044106380.024
regulation of ion transportGO:00432692450.024
positive regulation of response to stimulusGO:00485842850.024
cell part morphogenesisGO:00329901230.023
cellular lipid metabolic processGO:00442552080.023
Rat
regulation of neurogenesisGO:00507672470.023
response to ethanolGO:00454711620.023
Rat
peptide transportGO:0015833970.023
regulation of anatomical structure sizeGO:00900661350.023
carbohydrate derivative metabolic processGO:19011353460.023
Rat
regulation of cell differentiationGO:00455953200.023
cellular amino acid metabolic processGO:00065201070.023
Rat
response to carbohydrateGO:00097431830.023
Rat
regulation of cell developmentGO:00602842630.023
response to monosaccharideGO:00342841590.023
Rat
hormone transportGO:00099141210.022
multi organism reproductive processGO:00447032620.022
response to oxygen levelsGO:00704822650.022
Rat
4 chlorobiphenyl metabolic processGO:001888010.022
positive regulation of nervous system developmentGO:00519621780.022
brain developmentGO:00074202470.022
Rat
synaptic growth at neuromuscular junctionGO:005112410.022
cellular catabolic processGO:00442482950.022
g protein coupled receptor signaling pathwayGO:00071862420.022
positive regulation of lipid kinase activityGO:009021820.021
carboxylic acid transportGO:00469421150.021
nucleoside phosphate metabolic processGO:00067532830.021
immune system processGO:00023762040.021
regulation of cellular ketone metabolic processGO:0010565270.021
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
regulation of nervous system developmentGO:00519602640.021
regulation of tube sizeGO:0035150890.021
cellular response to external stimulusGO:00714961180.021
development of primary female sexual characteristicsGO:0046545560.021
positive regulation of biosynthetic processGO:00098913190.021
gamete generationGO:00072761240.021
peptide secretionGO:0002790860.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
regulation of transferase activityGO:00513381230.020
purine nucleotide metabolic processGO:00061632290.020
negative regulation of signalingGO:00230571570.020
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.020
negative regulation of response to stimulusGO:00485851550.020
nucleotide metabolic processGO:00091172790.020
positive regulation of cellular amine metabolic processGO:003324030.020
positive regulation of phosphorylationGO:00423271770.020
negative regulation of molecular functionGO:00440921330.020
response to inorganic substanceGO:00100353770.020
Rat
circadian rhythmGO:0007623880.020
regulation of vesicle mediated transportGO:0060627810.020
positive regulation of programmed cell deathGO:00430681570.020
cellular response to interferon gammaGO:0071346140.020
positive regulation of phosphorus metabolic processGO:00105622620.020
locomotionGO:00400112370.020
regulation of synaptic transmissionGO:00508041410.020
positive regulation of cell differentiationGO:00455972170.020
cellular hormone metabolic processGO:0034754490.020
chemosensory behaviorGO:000763520.020
positive regulation of transportGO:00510502450.019
positive regulation of cell deathGO:00109421840.019
regulation of intracellular signal transductionGO:19025312180.019
positive regulation of signalingGO:00230562700.019
developmental process involved in reproductionGO:00030061590.019
protein transportGO:00150311320.019
sensory perceptionGO:00076001010.019
Rat
regulation of system processGO:00440572080.019
regulation of cellular amine metabolic processGO:003323880.019
positive regulation of cell developmentGO:00107201760.019
cellular response to insulin stimulusGO:0032869810.019
response to radiationGO:00093141370.019
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.019
response to cytokineGO:00340972150.019
cofactor metabolic processGO:0051186950.019
Rat
peptide hormone secretionGO:0030072840.019
positive regulation of protein modification processGO:00314011420.019
sexual reproductionGO:00199531480.019
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.019
regulation of cell motilityGO:20001451310.019
positive regulation of cellular component organizationGO:00511302000.019
negative regulation of rna biosynthetic processGO:19026791180.019
hormone secretionGO:00468791150.018
neuron projection morphogenesisGO:00488121220.018
purine ribonucleotide metabolic processGO:00091502270.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
reactive oxygen species metabolic processGO:0072593370.018
positive regulation of protein phosphorylationGO:00019341350.018
regulation of cell projection organizationGO:00313441750.018
dephosphorylationGO:0016311980.018
muscle contractionGO:0006936880.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.018
negative regulation of rna metabolic processGO:00512531230.018
female sex differentiationGO:0046660590.018
negative regulation of developmental processGO:00510931250.018
ribose phosphate metabolic processGO:00196932350.017
insulin secretionGO:0030073690.017
positive regulation of cell proliferationGO:00082842490.017
response to starvationGO:0042594590.017
response to insulinGO:00328681330.017
response to interleukin 1GO:0070555550.017
regulation of kinase activityGO:00435491170.017
regulation of protein modification processGO:00313991940.017
reproductive system developmentGO:00614581280.017
multi multicellular organism processGO:00447061380.017
small gtpase mediated signal transductionGO:0007264360.017
cell morphogenesis involved in differentiationGO:00009041190.017
positive regulation of secretion by cellGO:19035321280.017
positive regulation of cytosolic calcium ion concentrationGO:00072041220.017
negative regulation of cellular protein metabolic processGO:00322691060.017
organic substance catabolic processGO:19015753160.017
olfactory behaviorGO:004204820.017
anterior posterior pattern specificationGO:000995210.017
catabolic processGO:00090563510.017
lipid biosynthetic processGO:00086101280.016
response to mineralocorticoidGO:0051385490.016
Rat
negative regulation of secretion by cellGO:1903531720.016
positive regulation of rna biosynthetic processGO:19026801970.016
spindle organizationGO:000705120.016
regulation of hydrolase activityGO:00513361430.016
positive regulation of secretionGO:00510471400.016
dendrite developmentGO:0016358720.016
axis specificationGO:000979840.016
cell projection morphogenesisGO:00488581230.016
brain renin angiotensin systemGO:000203530.016
reactive oxygen species biosynthetic processGO:190340980.016
muscle system processGO:00030121150.016
alpha amino acid catabolic processGO:1901606200.016
calcium ion homeostasisGO:00550741620.016
organophosphate biosynthetic processGO:00904071430.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
cytosolic calcium ion homeostasisGO:00514801400.015
cellular component movementGO:00069282480.015
purine containing compound metabolic processGO:00725212530.015
cellular component morphogenesisGO:00329891550.015
response to reactive oxygen speciesGO:00003021200.015
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
response to purine containing compoundGO:00140741260.015
divalent metal ion transportGO:00708381320.015
cellular calcium ion homeostasisGO:00068741600.015
positive regulation of protein metabolic processGO:00512471780.015
positive regulation of transcription dna templatedGO:00458931970.015
embryonic pattern specificationGO:000988010.015
cell growthGO:00160491040.015
protein targetingGO:0006605610.015
divalent inorganic cation transportGO:00725111340.015
positive regulation of cellular protein metabolic processGO:00322701670.015
peptidyl amino acid modificationGO:00181931260.015
carbohydrate metabolic processGO:00059751300.015
regulation of neuron projection developmentGO:00109751610.015
negative regulation of transcription dna templatedGO:00458921160.015
coenzyme metabolic processGO:0006732860.015
Rat
ribonucleotide metabolic processGO:00092592310.015
response to decreased oxygen levelsGO:00362932370.015
Rat
purine nucleotide biosynthetic processGO:0006164830.015
negative regulation of cell communicationGO:00106481580.015
carbohydrate derivative biosynthetic processGO:19011371240.015
inorganic cation transmembrane transportGO:00986622020.015
organ morphogenesisGO:0009887750.015
nucleoside metabolic processGO:00091161790.015
biphenyl catabolic processGO:007098020.014
gastrulationGO:000736920.014
reproductive structure developmentGO:00486081280.014
response to transition metal nanoparticleGO:19902671220.014
Rat
aromatic compound catabolic processGO:00194391680.014
cytoplasmic transportGO:00164821150.014
positive regulation of apoptotic processGO:00430651540.014
carboxylic acid biosynthetic processGO:0046394830.014
Rat
vesicle mediated transportGO:00161921810.014
Rat
cell type specific apoptotic processGO:00972851340.014
single organism cellular localizationGO:19025801020.014
regulation of anatomical structure morphogenesisGO:00226031410.014
positive regulation of neuron differentiationGO:00456661260.014
cellular amide metabolic processGO:0043603440.014
negative regulation of protein metabolic processGO:00512481140.014
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.014
organic acid transportGO:00158491160.014
negative regulation of signal transductionGO:0009968830.014
positive regulation of developmental processGO:00510942830.013
adult locomotory behaviorGO:000834440.013
purine ribonucleoside metabolic processGO:00461281680.013
regulation of insulin secretionGO:0050796650.013
acute inflammatory responseGO:0002526580.013
cellular response to abiotic stimulusGO:0071214850.013
oxidation reduction processGO:00551143040.013
ribonucleoside metabolic processGO:00091191740.013
positive regulation of molecular functionGO:00440932300.013
positive regulation of signal transductionGO:00099671750.013
nucleoside phosphate biosynthetic processGO:19012931020.013
organic anion transportGO:00157111320.013
single organism organelle organizationGO:19025891800.013
amide transportGO:00428861050.013
neuromuscular processGO:005090520.013
response to tumor necrosis factorGO:0034612560.013
cytokine biosynthetic processGO:004208930.013
camp metabolic processGO:0046058630.013
peptide biosynthetic processGO:004304330.013
positive regulation of neurogenesisGO:00507691650.013
negative regulation of catalytic activityGO:00430861030.013
positive regulation of neuron projection developmentGO:0010976990.013
olfactory learningGO:000835510.013
reactive nitrogen species metabolic processGO:200105710.013
regulation of peptide hormone secretionGO:0090276800.012
positive regulation of rna metabolic processGO:00512542030.012
response to woundingGO:00096112540.012
regulation of hormone secretionGO:00468831060.012
response to nicotineGO:0035094510.012
Rat
negative regulation of cell proliferationGO:00082851190.012
organic cyclic compound catabolic processGO:19013611750.012
formation of primary germ layerGO:000170410.012
cell cycleGO:00070491010.012
protein homooligomerizationGO:0051260910.012
regulation of neuron apoptotic processGO:0043523830.012
coumarin catabolic processGO:004622630.012
intracellular protein transportGO:0006886790.012
positive regulation of kinase activityGO:0033674770.012
cellular response to tumor necrosis factorGO:0071356460.012
negative regulation of hormone secretionGO:0046888460.012
calcium ion transportGO:00068161310.012
agingGO:00075682410.012
Rat
steroid metabolic processGO:0008202730.012
eye morphogenesisGO:004859240.012
gonad developmentGO:00084061040.012
glycosyl compound metabolic processGO:19016571820.012
Rat
regulation of reactive oxygen species biosynthetic processGO:190342650.012
protein localizationGO:00081041910.011
multicellular organism growthGO:003526410.011
hormone metabolic processGO:0042445690.011
smooth muscle contractionGO:0006939370.011
negative regulation of neurogenesisGO:0050768780.011
small molecule biosynthetic processGO:00442831240.011
Rat
response to alkaloidGO:00432791320.011
Rat
ras protein signal transductionGO:0007265290.011
regulation of blood circulationGO:19035221100.011
antigen processing and presentationGO:001988220.011
heart morphogenesisGO:000300730.011
development of primary sexual characteristicsGO:00451371070.011
response to electrical stimulusGO:0051602560.011
Rat
positive regulation of cell projection organizationGO:00313461110.011
single organism carbohydrate metabolic processGO:00447231180.011
ribonucleotide biosynthetic processGO:0009260850.011
positive regulation of transferase activityGO:0051347810.011
cellular response to mechanical stimulusGO:0071260480.011
positive regulation of intracellular signal transductionGO:19025331380.011
muscle structure developmentGO:0061061870.011
gland developmentGO:00487321550.011
response to increased oxygen levelsGO:0036296450.011
positive regulation of cell communicationGO:00106472710.011
carbohydrate homeostasisGO:0033500750.011
Rat
sensory perception of painGO:0019233730.011
multicellular organismal signalingGO:0035637440.011
regulation of membrane potentialGO:00423911100.011
heterocycle catabolic processGO:00467001670.011
growthGO:00400071650.011
purine nucleoside metabolic processGO:00422781690.011
response to activityGO:0014823730.011
Rat
regulation of nucleotide biosynthetic processGO:0030808470.011
response to hydrogen peroxideGO:0042542890.011
membrane organizationGO:0061024940.011
regulation of synaptic plasticityGO:0048167700.011
positive regulation of mapk cascadeGO:0043410920.010
cell motilityGO:00488702020.010
dna metabolic processGO:0006259960.010
exocytosisGO:0006887600.010
immune responseGO:00069551040.010
negative regulation of neuron deathGO:1901215690.010
transcription from rna polymerase ii promoterGO:00063662520.010
negative regulation of cellular component organizationGO:0051129830.010
cation transmembrane transportGO:00986552630.010
male gamete generationGO:0048232990.010
embryonic axis specificationGO:000057810.010
nuclear importGO:0051170350.010
sex differentiationGO:00075481130.010
forebrain developmentGO:0030900980.010
Rat
lipid storageGO:001991510.010
sensory organ developmentGO:0007423740.010
regulation of nucleotide metabolic processGO:00061401170.010
organonitrogen compound catabolic processGO:19015651790.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
mitotic spindle organizationGO:000705220.010
negative regulation of phosphate metabolic processGO:0045936800.010
axon developmentGO:0061564960.010
establishment of protein localizationGO:00451841410.010
response to organophosphorusGO:00466831020.010

Tph1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.034
disease of cellular proliferationDOID:1456600.017
musculoskeletal system diseaseDOID:1700.016
cancerDOID:16200.014
central nervous system diseaseDOID:33100.012
organ system cancerDOID:005068600.011
disease of metabolismDOID:001466700.011