Rattus norvegicus

28 known processes

Tph2

tryptophan hydroxylase 2

(Aliases: Ntph)

Tph2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
programmed cell deathGO:00125013920.072
cellular response to endogenous stimulusGO:00714953770.060
Rat
cellular response to oxygen containing compoundGO:19017013860.060
Rat
response to nutrient levelsGO:00316673700.057
apoptotic processGO:00069153810.055
neuron differentiationGO:00301823680.055
anatomical structure morphogenesisGO:00096532980.049
neuron developmentGO:00486662860.047
regulation of apoptotic processGO:00429813350.047
cellular response to nitrogen compoundGO:19016992100.047
Rat
regulation of cell proliferationGO:00421273590.047
intracellular signal transductionGO:00355563140.046
regulation of programmed cell deathGO:00430673410.044
regulation of rna biosynthetic processGO:20011413810.044
neuron projection developmentGO:00311752730.044
macromolecular complex subunit organizationGO:00439333390.043
response to extracellular stimulusGO:00099913800.043
protein phosphorylationGO:00064683450.042
cell projection organizationGO:00300303020.042
response to peptide hormoneGO:00434342780.041
Rat
rna biosynthetic processGO:00327743800.040
cellular response to stressGO:00335542690.040
regulation of phosphate metabolic processGO:00192203490.040
regulation of cellular protein metabolic processGO:00322682670.039
positive regulation of multicellular organismal processGO:00512403870.038
chemical homeostasisGO:00488782920.038
Rat
regulation of transcription dna templatedGO:00063553740.038
reproductive processGO:00224143720.037
regulation of phosphorus metabolic processGO:00511743490.037
cellular response to organic cyclic compoundGO:00714072020.037
Rat
regulation of cell differentiationGO:00455953200.037
secretionGO:00469033070.037
regulation of signal transductionGO:00099663180.037
protein complex subunit organizationGO:00718223020.037
regulation of cellular localizationGO:00603412630.036
cellular response to growth factor stimulusGO:00713631620.036
Rat
cellular response to hormone stimulusGO:00328702470.036
regulation of cellular component organizationGO:00511283680.036
negative regulation of metabolic processGO:00098923310.036
regulation of rna metabolic processGO:00512523910.036
ion transmembrane transportGO:00342203650.036
cation transportGO:00068123820.035
macromolecular complex assemblyGO:00650032730.035
positive regulation of biosynthetic processGO:00098913190.035
positive regulation of phosphate metabolic processGO:00459372620.035
positive regulation of nitrogen compound metabolic processGO:00511733340.035
cellular catabolic processGO:00442482950.035
cellular ketone metabolic processGO:0042180510.034
regulation of multicellular organismal developmentGO:20000263760.034
transcription dna templatedGO:00063513770.034
regulation of cellular amino acid metabolic processGO:000652120.034
positive regulation of cell proliferationGO:00082842490.034
rna metabolic processGO:00160704060.034
regulation of protein metabolic processGO:00512462890.034
positive regulation of gene expressionGO:00106282440.034
oxoacid metabolic processGO:00434362900.034
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.034
response to inorganic substanceGO:00100353770.034
cellular component biogenesisGO:00440853680.033
regulation of intracellular signal transductionGO:19025312180.033
homeostatic processGO:00425923310.033
Rat
cellular component assemblyGO:00226073600.033
central nervous system developmentGO:00074173110.033
Rat
organic acid metabolic processGO:00060822920.032
Rat
cellular amino acid metabolic processGO:00065201070.032
Rat
amine metabolic processGO:0009308380.032
regulation of cellular ketone metabolic processGO:0010565270.032
regulation of neurogenesisGO:00507672470.032
positive regulation of phosphorus metabolic processGO:00105622620.032
positive regulation of cellular biosynthetic processGO:00313282950.032
cellular chemical homeostasisGO:00550822470.032
Rat
nucleic acid templated transcriptionGO:00976593790.032
cellular amine metabolic processGO:0044106380.031
protein complex assemblyGO:00064612630.031
positive regulation of molecular functionGO:00440932300.031
regulation of molecular functionGO:00650093980.031
transmembrane transportGO:00550854120.031
regulation of neuron differentiationGO:00456642080.031
regulation of nucleic acid templated transcriptionGO:19035063800.030
single organism biosynthetic processGO:00447113420.030
Rat
nucleobase containing small molecule metabolic processGO:00550863160.030
positive regulation of signalingGO:00230562700.030
protein complex biogenesisGO:00702712630.030
cellular homeostasisGO:00197252520.030
Rat
carbohydrate derivative metabolic processGO:19011353460.030
Rat
regulation of protein modification processGO:00313991940.030
positive regulation of developmental processGO:00510942830.030
response to oxygen levelsGO:00704822650.030
Rat
carboxylic acid metabolic processGO:00197522890.030
Rat
single organism catabolic processGO:00447122830.030
brain developmentGO:00074202470.030
Rat
positive regulation of transportGO:00510502450.030
negative regulation of macromolecule metabolic processGO:00106052600.029
organophosphate metabolic processGO:00196373700.029
organic substance catabolic processGO:19015753160.029
response to carbohydrateGO:00097431830.029
Rat
response to hypoxiaGO:00016662310.029
Rat
negative regulation of cellular metabolic processGO:00313242810.028
purine ribonucleotide metabolic processGO:00091502270.028
positive regulation of cell deathGO:00109421840.028
response to growth factorGO:00708481890.028
Rat
cell cell signalingGO:00072673350.028
Rat
response to decreased oxygen levelsGO:00362932370.028
Rat
cell motilityGO:00488702020.028
positive regulation of cell communicationGO:00106472710.028
small gtpase mediated signal transductionGO:0007264360.028
transcription from rna polymerase ii promoterGO:00063662520.028
regulation of nervous system developmentGO:00519602640.028
nucleotide metabolic processGO:00091172790.027
purine containing compound metabolic processGO:00725212530.027
regulation of cell projection organizationGO:00313441750.027
regulation of response to stressGO:00801341260.027
regulation of system processGO:00440572080.027
regulation of catalytic activityGO:00507903040.027
single organism reproductive processGO:00447022970.027
secretion by cellGO:00329402480.027
nucleoside phosphate metabolic processGO:00067532830.027
macromolecule localizationGO:00330362520.027
regulation of neuron projection developmentGO:00109751610.026
rhythmic processGO:00485111560.026
response to acid chemicalGO:00011012220.026
Rat
regulation of cellular amine metabolic processGO:003323880.026
neuron projection morphogenesisGO:00488121220.026
regulation of secretionGO:00510462240.026
positive regulation of rna metabolic processGO:00512542030.026
regulation of cell developmentGO:00602842630.026
cell type specific apoptotic processGO:00972851340.026
negative regulation of apoptotic processGO:00430661810.026
cell morphogenesisGO:00009021420.026
ribose phosphate metabolic processGO:00196932350.026
response to estrogenGO:00436272320.026
regulation of secretion by cellGO:19035302080.026
response to corticosteroidGO:00319602350.025
negative regulation of programmed cell deathGO:00430691830.025
positive regulation of cell differentiationGO:00455972170.025
cellular component morphogenesisGO:00329891550.025
cellular component movementGO:00069282480.025
metal ion transportGO:00300012890.025
cellular response to organonitrogen compoundGO:00714171970.025
Rat
purine nucleotide metabolic processGO:00061632290.025
protein oligomerizationGO:00512591910.025
catabolic processGO:00090563510.024
positive regulation of rna biosynthetic processGO:19026801970.024
response to peptideGO:19016522920.024
Rat
response to woundingGO:00096112540.024
positive regulation of cellular amino acid metabolic processGO:004576410.024
neurological system processGO:00508772190.024
Rat
negative regulation of cell communicationGO:00106481580.024
ras protein signal transductionGO:0007265290.024
response to nutrientGO:00075842480.024
defense responseGO:00069521940.024
positive regulation of protein metabolic processGO:00512471780.024
positive regulation of nucleic acid templated transcriptionGO:19035081970.024
regulation of protein phosphorylationGO:00019321830.023
muscle system processGO:00030121150.023
response to cytokineGO:00340972150.023
organelle organizationGO:00069962660.023
response to glucocorticoidGO:00513842230.023
positive regulation of response to stimulusGO:00485842850.023
regulation of phosphorylationGO:00423252480.023
response to ketoneGO:19016541820.023
Rat
ribonucleotide metabolic processGO:00092592310.023
g protein coupled receptor signaling pathwayGO:00071862420.023
response to monosaccharideGO:00342841590.023
Rat
head developmentGO:00603222470.023
Rat
nitrogen compound transportGO:00717052290.022
Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
tissue developmentGO:00098882520.022
organic cyclic compound catabolic processGO:19013611750.022
positive regulation of macromolecule biosynthetic processGO:00105572470.022
synaptic transmissionGO:00072682350.022
Rat
gland developmentGO:00487321550.022
multicellular organism reproductionGO:00325042330.022
positive regulation of phosphorylationGO:00423271770.022
positive regulation of transcription dna templatedGO:00458931970.021
multi organism reproductive processGO:00447032620.021
positive regulation of cellular amine metabolic processGO:003324030.021
negative regulation of nitrogen compound metabolic processGO:00511721610.021
nucleoside metabolic processGO:00091161790.021
positive regulation of programmed cell deathGO:00430681570.021
locomotionGO:00400112370.021
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
regulation of anatomical structure sizeGO:00900661350.021
reproductionGO:00000032450.021
positive regulation of apoptotic processGO:00430651540.021
response to estradiolGO:00323551640.020
Rat
positive regulation of cellular protein metabolic processGO:00322701670.020
positive regulation of signal transductionGO:00099671750.020
cellular response to peptideGO:19016531330.020
response to metal ionGO:00100382530.020
negative regulation of gene expressionGO:00106291990.020
positive regulation of protein modification processGO:00314011420.020
agingGO:00075682410.020
Rat
localization of cellGO:00516742020.020
blood circulationGO:00080151830.020
cellular nitrogen compound catabolic processGO:00442701630.020
cellular response to lipidGO:00713962010.020
developmental process involved in reproductionGO:00030061590.020
negative regulation of cell deathGO:00605482290.020
immune system processGO:00023762040.020
ion homeostasisGO:00508012120.019
behaviorGO:00076102050.019
Rat
response to hexoseGO:00097461440.019
Rat
positive regulation of catalytic activityGO:00430851840.019
response to glucoseGO:00097491360.019
Rat
growthGO:00400071650.019
monovalent inorganic cation transportGO:00156721720.019
negative regulation of response to stimulusGO:00485851550.019
cellular cation homeostasisGO:00300031800.019
heterocycle catabolic processGO:00467001670.019
negative regulation of biosynthetic processGO:00098901680.019
glycosyl compound metabolic processGO:19016571820.019
Rat
nucleobase containing compound catabolic processGO:00346551520.019
positive regulation of intracellular signal transductionGO:19025331380.019
cell part morphogenesisGO:00329901230.018
inorganic ion transmembrane transportGO:00986602290.018
signal releaseGO:00230611450.018
positive regulation of cellular component organizationGO:00511302000.018
nucleoside triphosphate metabolic processGO:00091411440.018
response to vitaminGO:00332731310.018
negative regulation of signalingGO:00230571570.018
neuron apoptotic processGO:0051402880.018
heart morphogenesisGO:000300730.018
non canonical wnt signaling pathwayGO:003556730.018
positive regulation of cell developmentGO:00107201760.018
regulation of membrane potentialGO:00423911100.018
response to alkaloidGO:00432791320.018
Rat
regulation of cell migrationGO:00303341280.018
cellular response to peptide hormone stimulusGO:00713751200.018
regulation of hormone levelsGO:00108171870.018
reproductive structure developmentGO:00486081280.018
organonitrogen compound catabolic processGO:19015651790.018
regulation of purine nucleotide metabolic processGO:19005421150.017
purine containing compound catabolic processGO:00725231380.017
positive regulation of protein phosphorylationGO:00019341350.017
negative regulation of macromolecule biosynthetic processGO:00105581480.017
negative regulation of transportGO:00510511360.017
metal ion homeostasisGO:00550651860.017
response to oxidative stressGO:00069791860.017
cellular ion homeostasisGO:00068731840.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
regulation of cell motilityGO:20001451310.017
cell morphogenesis involved in neuron differentiationGO:00486671060.017
purine ribonucleoside metabolic processGO:00461281680.017
cellular calcium ion homeostasisGO:00068741600.017
positive regulation of neurogenesisGO:00507691650.017
proteolysisGO:00065081750.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
positive regulation of nervous system developmentGO:00519621780.017
establishment of protein localizationGO:00451841410.017
protein localizationGO:00081041910.017
protein transportGO:00150311320.017
intracellular transportGO:00469071850.017
response to external biotic stimulusGO:00432072210.017
Rat
biological adhesionGO:00226101100.017
regulation of canonical wnt signaling pathwayGO:006082840.016
embryonic skeletal system morphogenesisGO:004870430.016
gastrulationGO:000736920.016
positive regulation of neuron differentiationGO:00456661260.016
carbohydrate derivative catabolic processGO:19011361470.016
negative regulation of cellular biosynthetic processGO:00313271610.016
regulation of locomotionGO:00400121480.016
circulatory system processGO:00030131830.016
cell morphogenesis involved in differentiationGO:00009041190.016
single organism behaviorGO:00447081300.016
cation homeostasisGO:00550801950.016
organophosphate biosynthetic processGO:00904071430.016
multicellular organismal reproductive processGO:00486092330.016
bmp signaling pathwayGO:003050940.016
cellular response to cytokine stimulusGO:00713451270.016
regulation of cellular component movementGO:00512701500.016
lipid metabolic processGO:00066292830.016
Rat
nucleotide catabolic processGO:00091661390.016
anion transportGO:00068201780.016
wound healingGO:00420601220.016
cellular response to alcoholGO:0097306870.016
muscle contractionGO:0006936880.015
regulation of ion transportGO:00432692450.015
cellular response to external stimulusGO:00714961180.015
cellular protein localizationGO:00346131220.015
negative regulation of multicellular organismal processGO:00512412030.015
Rat
sensory perceptionGO:00076001010.015
Rat
cellular metal ion homeostasisGO:00068751720.015
potassium ion transportGO:0006813970.015
aromatic compound catabolic processGO:00194391680.015
organ formationGO:004864530.015
cellular response to steroid hormone stimulusGO:0071383930.015
protein heterooligomerizationGO:0051291890.015
regulation of anatomical structure morphogenesisGO:00226031410.015
regulation of tube sizeGO:0035150890.015
response to other organismGO:00517072200.015
Rat
nucleoside catabolic processGO:00091641260.015
cation transmembrane transportGO:00986552630.015
mesoderm developmentGO:000749820.015
cell cycleGO:00070491010.015
positive regulation of secretionGO:00510471400.015
divalent inorganic cation homeostasisGO:00725071650.015
positive regulation of cellular component movementGO:00512721020.015
ribonucleotide biosynthetic processGO:0009260850.015
calcium ion transportGO:00068161310.015
axis specificationGO:000979840.015
neuron deathGO:00709971270.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
cellular macromolecule localizationGO:00707271220.015
organophosphate catabolic processGO:00464341480.014
cell migrationGO:00164771970.014
carbohydrate derivative biosynthetic processGO:19011371240.014
ribonucleoside metabolic processGO:00091191740.014
immune responseGO:00069551040.014
hormone secretionGO:00468791150.014
response to purine containing compoundGO:00140741260.014
regenerationGO:00310991630.014
vascular process in circulatory systemGO:0003018960.014
purine ribonucleoside catabolic processGO:00461301240.014
response to mechanical stimulusGO:00096121340.014
axon developmentGO:0061564960.014
reactive oxygen species metabolic processGO:0072593370.014
embryonic skeletal system developmentGO:004870630.014
calcium ion homeostasisGO:00550741620.014
cell projection morphogenesisGO:00488581230.014
negative regulation of nucleic acid templated transcriptionGO:19035071170.014
purine nucleoside catabolic processGO:00061521240.014
purine nucleotide biosynthetic processGO:0006164830.014
anterior posterior pattern specificationGO:000995210.014
purine nucleoside metabolic processGO:00422781690.014
circadian rhythmGO:0007623880.014
regulation of protein kinase activityGO:00458591050.014
forebrain developmentGO:0030900980.014
Rat
regulation of hydrolase activityGO:00513361430.014
regulation of growthGO:00400081050.014
regulation of catabolic processGO:00098941130.014
regulation of neuron apoptotic processGO:0043523830.014
cell adhesionGO:00071551100.014
wnt signaling pathway planar cell polarity pathwayGO:006007120.014
single organism cellular localizationGO:19025801020.014
purine ribonucleoside triphosphate metabolic processGO:00092051400.014
ribonucleotide catabolic processGO:00092611360.013
cellular lipid metabolic processGO:00442552080.013
Rat
salivary gland developmentGO:000743130.013
organ regenerationGO:00311001010.013
glycosyl compound catabolic processGO:19016581260.013
cell activationGO:0001775970.013
regulation of synaptic transmissionGO:00508041410.013
reproductive system developmentGO:00614581280.013
muscle structure developmentGO:0061061870.013
single organism organelle organizationGO:19025891800.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
small molecule biosynthetic processGO:00442831240.013
Rat
organic anion transportGO:00157111320.013
negative regulation of rna biosynthetic processGO:19026791180.013
regulation of nucleotide metabolic processGO:00061401170.013
negative regulation of transcription dna templatedGO:00458921160.013
purine ribonucleotide catabolic processGO:00091541360.013
single organism intracellular transportGO:19025821660.013
peptide transportGO:0015833970.013
negative regulation of protein metabolic processGO:00512481140.013
establishment of tissue polarityGO:000716420.013
negative regulation of innate immune responseGO:004582440.013
liver developmentGO:0001889900.013
peptide hormone secretionGO:0030072840.013
ribonucleoside triphosphate catabolic processGO:00092031220.013
eye morphogenesisGO:004859240.013
positive regulation of purine nucleotide metabolic processGO:1900544910.013
regulation of establishment of planar polarityGO:009017520.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
negative regulation of molecular functionGO:00440921330.013
regulation of response to woundingGO:1903034690.013
developmental growthGO:00485891000.013
circulatory system developmentGO:00723591340.013
Rat
sex differentiationGO:00075481130.013
regulation of response to external stimulusGO:00321011060.013
ribose phosphate biosynthetic processGO:0046390870.013
regulation of body fluid levelsGO:0050878900.013
purine nucleotide catabolic processGO:00061951360.013
cytoplasmic transportGO:00164821150.013
regulation of neuron deathGO:19012141150.013
divalent metal ion transportGO:00708381320.013
negative regulation of secretionGO:0051048820.013
establishment of planar polarityGO:000173610.013
ribonucleoside catabolic processGO:00424541260.013
negative regulation of rna metabolic processGO:00512531230.013
cell growthGO:00160491040.013
negative regulation of cell differentiationGO:0045596990.013
regulation of kinase activityGO:00435491170.013
sexual reproductionGO:00199531480.013
negative regulation of nervous system developmentGO:0051961790.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
action potentialGO:0001508540.012
negative regulation of secretion by cellGO:1903531720.012
hepaticobiliary system developmentGO:0061008900.012
amide transportGO:00428861050.012
regulation of blood vessel sizeGO:0050880890.012
negative regulation of neurogenesisGO:0050768780.012
cyclic nucleotide biosynthetic processGO:0009190630.012
lipid biosynthetic processGO:00086101280.012
response to toxic substanceGO:00096361330.012
Rat
multi multicellular organism processGO:00447061380.012
response to bacteriumGO:00096172000.012
Rat
gliogenesisGO:0042063930.012
response to radiationGO:00093141370.012
Rat
sensory perception of painGO:0019233730.012
nucleoside triphosphate catabolic processGO:00091431230.012
negative regulation of cellular component organizationGO:0051129830.012
positive regulation of hydrolase activityGO:0051345860.012
positive regulation of cell projection organizationGO:00313461110.012
inorganic cation transmembrane transportGO:00986622020.012
positive regulation of secretion by cellGO:19035321280.012
negative regulation of phosphate metabolic processGO:0045936800.012
nucleoside phosphate biosynthetic processGO:19012931020.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
appendage morphogenesisGO:003510740.012
embryonic appendage morphogenesisGO:003511340.012
organ morphogenesisGO:0009887750.012
carbohydrate homeostasisGO:0033500750.012
Rat
regulation of muscle system processGO:0090257790.012
nucleotide biosynthetic processGO:0009165980.012
regulation of protein localizationGO:0032880810.012
positive regulation of nucleotide metabolic processGO:0045981910.012
regulation of protein transportGO:0051223680.012
response to reactive oxygen speciesGO:00003021200.012
positive regulation of ion transportGO:0043270940.012
negative regulation of signal transductionGO:0009968830.012
divalent inorganic cation transportGO:00725111340.011
hormone transportGO:00099141210.011
gamete generationGO:00072761240.011
regulation of peptide transportGO:0090087870.011
striated muscle tissue developmentGO:0014706580.011
epithelium developmentGO:0060429960.011
negative regulation of cell proliferationGO:00082851190.011
signal transduction by phosphorylationGO:00230141440.011
cellular response to abiotic stimulusGO:0071214850.011
inflammatory responseGO:00069541500.011
response to insulinGO:00328681330.011
regulation of establishment of protein localizationGO:0070201690.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
negative regulation of canonical wnt signaling pathwayGO:009009040.011
membrane organizationGO:0061024940.011
embryonic pattern specificationGO:000988010.011
organic acid transportGO:00158491160.011
multicellular organism growthGO:003526410.011
response to organophosphorusGO:00466831020.011
negative regulation of phosphorus metabolic processGO:0010563800.011
palate developmentGO:006002120.011
regulation of cell adhesionGO:0030155520.011
regulation of blood circulationGO:19035221100.011
peptidyl amino acid modificationGO:00181931260.011
protein homooligomerizationGO:0051260910.011
regulation of immune system processGO:00026821230.011
development of primary sexual characteristicsGO:00451371070.011
female pregnancyGO:00075651220.011
formation of primary germ layerGO:000170410.011
axonogenesisGO:0007409710.011
hematopoietic progenitor cell differentiationGO:000224420.011
transmission of nerve impulseGO:0019226420.011
neuronal action potentialGO:0019228350.011
striated muscle contractionGO:0006941440.011
intracellular protein transportGO:0006886790.011
peptide secretionGO:0002790860.011
response to biotic stimulusGO:00096072260.011
Rat
spermatogenesisGO:0007283990.011
glucose homeostasisGO:0042593750.011
Rat
organic hydroxy compound metabolic processGO:19016151150.011
Rat
olfactory behaviorGO:004204820.011
dendrite developmentGO:0016358720.010
regulation of cell morphogenesisGO:0022604770.010
jak stat cascadeGO:0007259260.010
rho protein signal transductionGO:0007266110.010
positive regulation of mapk cascadeGO:0043410920.010
positive regulation of kinase activityGO:0033674770.010
purine ribonucleotide biosynthetic processGO:0009152810.010
organonitrogen compound biosynthetic processGO:19015661670.010
Rat
response to ethanolGO:00454711620.010
Rat
positive regulation of neuron projection developmentGO:0010976990.010
cellular response to hexose stimulusGO:0071331650.010
Rat
chromosome segregationGO:000705920.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
negative regulation of cellular protein metabolic processGO:00322691060.010
response to molecule of bacterial originGO:00022371940.010
Rat
cyclic nucleotide metabolic processGO:0009187800.010
cytosolic calcium ion homeostasisGO:00514801400.010
limb morphogenesisGO:003510840.010
enzyme linked receptor protein signaling pathwayGO:00071671160.010
gonad developmentGO:00084061040.010

Tph2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.041
disease of anatomical entityDOID:700.041
sensory system diseaseDOID:005015500.020
musculoskeletal system diseaseDOID:1700.017
bone development diseaseDOID:008000600.015
connective tissue diseaseDOID:6500.015
bone diseaseDOID:008000100.015
disease of metabolismDOID:001466700.014
eye and adnexa diseaseDOID:149200.013
central nervous system diseaseDOID:33100.012
eye diseaseDOID:561400.011
retinal diseaseDOID:567900.011