Rattus norvegicus

0 known processes

Enpp6

ectonucleotide pyrophosphatase/phosphodiesterase 6

(Aliases: E-NPP 6)

Enpp6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193190.465
anatomical structure morphogenesisGO:00096532980.285
choline transportGO:001587140.207
regulation of nervous system developmentGO:00519602640.198
locomotionGO:00400112370.163
ossificationGO:0001503700.131
response to oxygen levelsGO:00704822650.122
cellular component movementGO:00069282480.122
regulation of hormone levelsGO:00108171870.119
transmembrane transportGO:00550854120.115
response to inorganic substanceGO:00100353770.112
cell cell signalingGO:00072673350.108
central nervous system developmentGO:00074173110.107
cation transmembrane transportGO:00986552630.106
homeostatic processGO:00425923310.101
cation transportGO:00068123820.098
positive regulation of signalingGO:00230562700.095
gliogenesisGO:0042063930.092
catabolic processGO:00090563510.091
Rat
positive regulation of response to stimulusGO:00485842850.091
regulation of nucleic acid templated transcriptionGO:19035063800.091
regulation of cell differentiationGO:00455953200.091
cellular response to stressGO:00335542690.090
Yeast
negative regulation of neurogenesisGO:0050768780.085
cell motilityGO:00488702020.085
response to hypoxiaGO:00016662310.083
nitrogen compound transportGO:00717052290.080
response to ethanolGO:00454711620.079
carboxylic acid metabolic processGO:00197522890.079
positive regulation of transportGO:00510502450.078
regulation of hormone secretionGO:00468831060.077
cell morphogenesisGO:00009021420.075
oxidation reduction processGO:00551143040.075
cellular component morphogenesisGO:00329891550.074
ion transmembrane transportGO:00342203650.073
cell morphogenesis involved in differentiationGO:00009041190.073
neuron differentiationGO:00301823680.072
regulation of multicellular organismal developmentGO:20000263760.071
response to growth factorGO:00708481890.071
synaptic transmissionGO:00072682350.071
cellular component biogenesisGO:00440853680.071
positive regulation of cell differentiationGO:00455972170.070
cellular response to growth factor stimulusGO:00713631620.068
brain developmentGO:00074202470.067
organic acid metabolic processGO:00060822920.066
cellular homeostasisGO:00197252520.066
cellular amino acid metabolic processGO:00065201070.066
reproductive processGO:00224143720.064
transcription dna templatedGO:00063513770.064
reproductive structure developmentGO:00486081280.064
cellular component assemblyGO:00226073600.063
positive regulation of cell developmentGO:00107201760.063
response to decreased oxygen levelsGO:00362932370.061
regulation of neuron differentiationGO:00456642080.061
cellular response to endogenous stimulusGO:00714953770.060
negative regulation of cell developmentGO:0010721820.060
secretionGO:00469033070.059
divalent metal ion transportGO:00708381320.059
organic hydroxy compound transportGO:0015850770.057
regulation of synaptic transmissionGO:00508041410.056
negative regulation of nervous system developmentGO:0051961790.056
cellular response to alcoholGO:0097306870.056
negative regulation of neuron differentiationGO:0045665620.056
response to mechanical stimulusGO:00096121340.055
regulation of neurogenesisGO:00507672470.055
oxoacid metabolic processGO:00434362900.054
regulation of ion transmembrane transportGO:00347651210.054
regulation of mapk cascadeGO:00434081160.054
neurological system processGO:00508772190.054
reproductive system developmentGO:00614581280.053
cell projection organizationGO:00300303020.053
blood vessel morphogenesisGO:0048514580.053
response to other organismGO:00517072200.052
regulation of neuronal synaptic plasticityGO:0048168310.052
positive regulation of developmental processGO:00510942830.051
regulation of locomotionGO:00400121480.051
organonitrogen compound catabolic processGO:19015651790.051
Rat
single organism catabolic processGO:00447122830.050
Rat
positive regulation of signal transductionGO:00099671750.050
regulation of signal transductionGO:00099663180.050
regulation of synaptic plasticityGO:0048167700.049
regulation of rna metabolic processGO:00512523910.049
positive regulation of molecular functionGO:00440932300.049
metal ion transportGO:00300012890.049
regulation of transferase activityGO:00513381230.048
protein complex assemblyGO:00064612630.048
regulation of protein modification processGO:00313991940.048
response to transition metal nanoparticleGO:19902671220.047
neuron developmentGO:00486662860.046
rna metabolic processGO:00160704060.046
organophosphate catabolic processGO:00464341480.046
Rat
response to estradiolGO:00323551640.046
cell migrationGO:00164771970.045
single organism biosynthetic processGO:00447113420.045
head developmentGO:00603222470.045
localization of cellGO:00516742020.044
signal transduction by phosphorylationGO:00230141440.044
regulation of phosphate metabolic processGO:00192203490.044
positive regulation of ion transportGO:0043270940.044
regulation of ion transportGO:00432692450.044
nucleic acid templated transcriptionGO:00976593790.044
agingGO:00075682410.044
neuron projection developmentGO:00311752730.043
organic acid transportGO:00158491160.043
carbohydrate derivative catabolic processGO:19011361470.043
circadian rhythmGO:0007623880.042
multi organism reproductive processGO:00447032620.042
antibiotic transportGO:004289120.042
nucleobase containing small molecule metabolic processGO:00550863160.042
Yeast
regulation of cell proliferationGO:00421273590.042
anion transportGO:00068201780.042
chemical homeostasisGO:00488782920.041
regulation of epithelial cell proliferationGO:0050678490.041
amine metabolic processGO:0009308380.041
Human Mouse Rat
response to metal ionGO:00100382530.041
mapk cascadeGO:00001651400.041
inorganic cation transmembrane transportGO:00986622020.040
regulation of transcription dna templatedGO:00063553740.040
positive regulation of cell communicationGO:00106472710.040
regulation of cellular component organizationGO:00511283680.040
cellular amine metabolic processGO:0044106380.040
Human Mouse Rat
regulation of molecular functionGO:00650093980.039
glial cell differentiationGO:0010001650.038
regulation of phosphorus metabolic processGO:00511743490.038
regulation of rna biosynthetic processGO:20011413810.038
regulation of cellular ketone metabolic processGO:0010565270.037
oligopeptide transportGO:000685740.037
hepaticobiliary system developmentGO:0061008900.037
positive regulation of neurogenesisGO:00507691650.036
macromolecular complex assemblyGO:00650032730.036
regulation of protein kinase activityGO:00458591050.036
regulation of kinase activityGO:00435491170.036
response to monosaccharideGO:00342841590.036
regulation of intracellular signal transductionGO:19025312180.036
regulation of neuron projection developmentGO:00109751610.035
protein complex biogenesisGO:00702712630.035
cell projection morphogenesisGO:00488581230.035
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.035
positive regulation of nervous system developmentGO:00519621780.035
single organism reproductive processGO:00447022970.035
negative regulation of multicellular organismal processGO:00512412030.035
cellular ketone metabolic processGO:0042180510.035
epithelial cell proliferationGO:0050673540.034
epithelial cell differentiationGO:0030855710.034
multicellular organism reproductionGO:00325042330.034
positive regulation of protein kinase activityGO:0045860730.034
response to glucocorticoidGO:00513842230.033
lipid metabolic processGO:00066292830.033
Human Rat
protein complex subunit organizationGO:00718223020.033
organic anion transportGO:00157111320.032
cell part morphogenesisGO:00329901230.032
developmental process involved in reproductionGO:00030061590.032
cellular catabolic processGO:00442482950.032
Rat
negative regulation of cell communicationGO:00106481580.032
intracellular signal transductionGO:00355563140.032
macromolecular complex subunit organizationGO:00439333390.032
positive regulation of catalytic activityGO:00430851840.032
positive regulation of multicellular organismal processGO:00512403870.031
response to peptide hormoneGO:00434342780.031
protein phosphorylationGO:00064683450.031
behaviorGO:00076102050.031
response to hexoseGO:00097461440.031
response to corticosteroidGO:00319602350.031
tissue developmentGO:00098882520.031
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.031
regulation of cell projection organizationGO:00313441750.031
carbohydrate derivative metabolic processGO:19011353460.031
regulation of synaptic transmission glutamatergicGO:0051966260.031
neuron projection morphogenesisGO:00488121220.030
cellular cation homeostasisGO:00300031800.030
organic cyclic compound catabolic processGO:19013611750.030
gonad developmentGO:00084061040.030
calcium ion homeostasisGO:00550741620.030
regulation of cellular amine metabolic processGO:003323880.030
ribonucleoside metabolic processGO:00091191740.030
hormone metabolic processGO:0042445690.029
response to radiationGO:00093141370.029
cellular chemical homeostasisGO:00550822470.029
positive regulation of programmed cell deathGO:00430681570.028
regulation of cellular amino acid metabolic processGO:000652120.028
response to carbohydrateGO:00097431830.028
cation homeostasisGO:00550801950.028
single organism behaviorGO:00447081300.028
positive regulation of cell proliferationGO:00082842490.028
hormone transportGO:00099141210.027
regulation of transmembrane transportGO:00347621220.027
divalent inorganic cation transportGO:00725111340.027
response to biotic stimulusGO:00096072260.027
positive regulation of cellular amine metabolic processGO:003324030.027
negative regulation of metabolic processGO:00098923310.027
rna biosynthetic processGO:00327743800.026
signal releaseGO:00230611450.026
lens development in camera type eyeGO:0002088130.026
sex differentiationGO:00075481130.026
cellular response to peptide hormone stimulusGO:00713751200.026
neurotransmitter transportGO:0006836420.026
regulation of organelle organizationGO:0033043800.026
regulation of metal ion transportGO:00109591180.026
regulation of cellular catabolic processGO:00313291010.026
gland developmentGO:00487321550.026
positive regulation of transcription dna templatedGO:00458931970.025
multicellular organism growthGO:003526410.025
single organism organelle organizationGO:19025891800.025
embryonic skeletal system developmentGO:004870630.025
epithelium developmentGO:0060429960.025
positive regulation of cellular protein metabolic processGO:00322701670.025
purine ribonucleoside metabolic processGO:00461281680.025
tissue remodelingGO:0048771400.025
angiogenesisGO:0001525530.024
lipid transportGO:0006869610.024
multicellular organismal homeostasisGO:0048871490.024
response to dexamethasoneGO:0071548490.024
carbohydrate derivative biosynthetic processGO:19011371240.024
positive regulation of transferase activityGO:0051347810.024
positive regulation of phosphorus metabolic processGO:00105622620.024
response to increased oxygen levelsGO:0036296450.024
cellular response to lipidGO:00713962010.024
lipid biosynthetic processGO:00086101280.024
regulation of cardiac muscle tissue developmentGO:0055024120.024
positive regulation of phosphate metabolic processGO:00459372620.024
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.024
regulation of anatomical structure sizeGO:00900661350.023
regulation of calcium ion transportGO:0051924770.023
response to nutrient levelsGO:00316673700.023
Yeast
response to testosteroneGO:0033574550.023
response to woundingGO:00096112540.023
protein oligomerizationGO:00512591910.023
programmed cell deathGO:00125013920.022
positive regulation of protein modification processGO:00314011420.022
response to nutrientGO:00075842480.022
sexual reproductionGO:00199531480.022
cellular response to organonitrogen compoundGO:00714171970.022
regulation of protein metabolic processGO:00512462890.022
negative regulation of response to stimulusGO:00485851550.022
monocarboxylic acid transportGO:0015718520.022
negative regulation of synaptic transmission gabaergicGO:003222960.022
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.022
amino acid transportGO:0006865700.022
purine containing compound metabolic processGO:00725212530.022
response to cytokineGO:00340972150.021
response to extracellular stimulusGO:00099913800.021
Yeast
cell proliferation in external granule layerGO:002192410.021
positive regulation of apoptotic processGO:00430651540.021
regulation of cellular protein metabolic processGO:00322682670.021
regulation of anatomical structure morphogenesisGO:00226031410.021
eye morphogenesisGO:004859240.021
regulation of apoptotic processGO:00429813350.021
positive regulation of mapk cascadeGO:0043410920.021
carboxylic acid catabolic processGO:0046395490.021
positive regulation of long term synaptic potentiationGO:190027340.021
negative regulation of developmental processGO:00510931250.021
cell adhesionGO:00071551100.021
tube developmentGO:0035295890.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
negative regulation of molecular functionGO:00440921330.021
purine ribonucleotide metabolic processGO:00091502270.021
sodium ion transmembrane transportGO:0035725670.021
response to alkaloidGO:00432791320.020
regulation of catalytic activityGO:00507903040.020
negative regulation of macromolecule metabolic processGO:00106052600.020
response to glucoseGO:00097491360.020
cardiovascular system developmentGO:00723581340.020
aromatic compound catabolic processGO:00194391680.020
multi multicellular organism processGO:00447061380.020
potassium ion transportGO:0006813970.020
ras protein signal transductionGO:0007265290.020
response to external biotic stimulusGO:00432072210.020
organic substance catabolic processGO:19015753160.020
Rat
cell morphogenesis involved in neuron differentiationGO:00486671060.020
regulation of purine nucleotide metabolic processGO:19005421150.020
positive regulation of ion transmembrane transportGO:0034767240.020
regulation of cell developmentGO:00602842630.020
proteolysisGO:00065081750.020
negative regulation of cell differentiationGO:0045596990.020
reproductionGO:00000032450.020
synaptic transmission gabaergicGO:0051932220.020
mechanoreceptor differentiationGO:004249020.019
monocarboxylic acid metabolic processGO:00327871520.019
nucleoside triphosphate metabolic processGO:00091411440.019
Yeast
response to cocaineGO:0042220390.019
positive regulation of nitrogen compound metabolic processGO:00511733340.019
organelle organizationGO:00069962660.019
regulation of cell migrationGO:00303341280.019
negative regulation of gene expressionGO:00106291990.019
positive regulation of transmembrane transportGO:0034764250.019
regulation of amine transportGO:0051952540.019
positive regulation of hormone secretionGO:0046887650.019
sodium independent organic anion transportGO:004325220.019
purine ribonucleoside catabolic processGO:00461301240.019
regulation of phosphorylationGO:00423252480.019
purine ribonucleoside triphosphate metabolic processGO:00092051400.019
regulation of catabolic processGO:00098941130.018
small gtpase mediated signal transductionGO:0007264360.018
divalent inorganic cation homeostasisGO:00725071650.018
small molecule biosynthetic processGO:00442831240.018
regulation of dendrite developmentGO:0050773590.018
cellular response to hormone stimulusGO:00328702470.018
regulation of secretionGO:00510462240.018
embryonic skeletal system morphogenesisGO:004870430.018
nucleoside triphosphate catabolic processGO:00091431230.018
carboxylic acid transportGO:00469421150.018
positive regulation of protein phosphorylationGO:00019341350.018
cell cycleGO:00070491010.018
circulatory system developmentGO:00723591340.018
cytosolic calcium ion homeostasisGO:00514801400.018
nucleoside catabolic processGO:00091641260.018
response to acid chemicalGO:00011012220.018
regulation of cell morphogenesisGO:0022604770.018
negative regulation of signalingGO:00230571570.018
cellular lipid metabolic processGO:00442552080.018
Rat
negative regulation of cell proliferationGO:00082851190.018
multicellular organismal reproductive processGO:00486092330.018
mesoderm developmentGO:000749820.018
purine nucleotide catabolic processGO:00061951360.018
negative regulation of cellular metabolic processGO:00313242810.018
activation of protein kinase activityGO:0032147470.017
sensory perception of painGO:0019233730.017
nucleotide catabolic processGO:00091661390.017
cellular response to cytokine stimulusGO:00713451270.017
glandular epithelial cell differentiationGO:000206740.017
cellular calcium ion homeostasisGO:00068741600.017
regulation of membrane potentialGO:00423911100.017
glycosyl compound metabolic processGO:19016571820.017
anatomical structure formation involved in morphogenesisGO:0048646830.017
developmental growthGO:00485891000.017
respiratory system developmentGO:0060541450.017
regulation of saliva secretionGO:004687730.017
ribonucleoside catabolic processGO:00424541260.017
development of primary sexual characteristicsGO:00451371070.017
regulation of cation channel activityGO:2001257230.017
ion homeostasisGO:00508012120.017
cellular response to external stimulusGO:00714961180.016
Yeast
defense responseGO:00069521940.016
regulation of canonical wnt signaling pathwayGO:006082840.016
limb morphogenesisGO:003510840.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
purine nucleoside catabolic processGO:00061521240.016
regulation of response to external stimulusGO:00321011060.016
transmission of nerve impulseGO:0019226420.016
peptidyl amino acid modificationGO:00181931260.016
ribonucleotide metabolic processGO:00092592310.016
involuntary skeletal muscle contractionGO:000301120.016
response to estrogenGO:00436272320.016
organonitrogen compound biosynthetic processGO:19015661670.016
neurotransmitter uptakeGO:000150430.016
purine nucleoside triphosphate catabolic processGO:00091461220.016
purine nucleotide metabolic processGO:00061632290.016
positive regulation of kinase activityGO:0033674770.016
lens fiber cell differentiationGO:007030630.015
cerebellar granule cell precursor proliferationGO:002193010.015
positive regulation of phosphorylationGO:00423271770.015
rhythmic processGO:00485111560.015
positive regulation of saliva secretionGO:004687830.015
detection of stimulusGO:0051606240.015
positive regulation of purine nucleotide metabolic processGO:1900544910.015
ribonucleoside triphosphate catabolic processGO:00092031220.015
telencephalon developmentGO:0021537620.015
cellular response to extracellular stimulusGO:0031668730.015
Yeast
calcium ion transportGO:00068161310.015
salivary gland developmentGO:000743130.015
regulation of purine nucleotide catabolic processGO:0033121650.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
nucleoside metabolic processGO:00091161790.015
intestinal absorptionGO:005089230.015
glucan metabolic processGO:0044042230.015
tissue morphogenesisGO:0048729220.014
detection of temperature stimulusGO:001604840.014
response to retinoic acidGO:0032526630.014
cell cycle processGO:0022402570.014
neuronal action potentialGO:0019228350.014
response to ketoneGO:19016541820.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
nucleobase containing compound catabolic processGO:00346551520.014
growthGO:00400071650.014
positive regulation of cytosolic calcium ion concentrationGO:00072041220.014
positive regulation of synaptic transmissionGO:0050806620.014
vascular process in circulatory systemGO:0003018960.014
alcohol metabolic processGO:0006066770.014
Human Mouse Rat
positive regulation of cell deathGO:00109421840.014
blood circulationGO:00080151830.014
nucleotide metabolic processGO:00091172790.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
regulation of vesicle mediated transportGO:0060627810.014
regulation of cellular localizationGO:00603412630.014
response to temperature stimulusGO:0009266940.014
regulation of homotypic cell cell adhesionGO:003411040.014
regulation of cellular component movementGO:00512701500.014
purine nucleoside metabolic processGO:00422781690.014
positive regulation of neuron projection developmentGO:0010976990.014
regulation of neurotransmitter levelsGO:0001505420.014
maintenance of locationGO:0051235170.014
regulation of synaptic transmission gabaergicGO:0032228170.014
positive regulation of biosynthetic processGO:00098913190.014
positive regulation of cell projection organizationGO:00313461110.013
organic hydroxy compound metabolic processGO:19016151150.013
Human Mouse Rat
forebrain developmentGO:0030900980.013
response to cgmpGO:007030530.013
diaphragm contractionGO:000208620.013
learning or memoryGO:0007611900.013
modified amino acid transportGO:0072337120.013
dopamine transportGO:0015872180.013
nucleoside phosphate metabolic processGO:00067532830.013
Yeast
sensory perceptionGO:00076001010.013
positive regulation of neuron differentiationGO:00456661260.013
gamete generationGO:00072761240.013
spinal cord developmentGO:0021510270.013
negative regulation of cellular component organizationGO:0051129830.013
male gamete generationGO:0048232990.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
positive regulation of defense responseGO:0031349370.013
inorganic ion transmembrane transportGO:00986602290.013
response to bacteriumGO:00096172000.013
cellular metal ion homeostasisGO:00068751720.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
organophosphate metabolic processGO:00196373700.013
Yeast Rat
neurotransmitter gated ion channel clusteringGO:007257830.013
inner ear receptor cell differentiationGO:006011320.013
monovalent inorganic cation transportGO:00156721720.013
response to lipopolysaccharideGO:00324961910.013
positive regulation of cellular catabolic processGO:0031331710.013
respiratory system processGO:000301630.013
ribose phosphate metabolic processGO:00196932350.013
nucleoside phosphate catabolic processGO:19012921400.013
heart morphogenesisGO:000300730.013
regulation of response to woundingGO:1903034690.013
glucose homeostasisGO:0042593750.013
carbohydrate metabolic processGO:00059751300.013
biological adhesionGO:00226101100.013
axon ensheathmentGO:0008366400.012
tripeptide transportGO:004293920.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
ribonucleotide catabolic processGO:00092611360.012
carbohydrate homeostasisGO:0033500750.012
sensory organ developmentGO:0007423740.012
regulation of peptide hormone secretionGO:0090276800.012
sensory perception of light stimulusGO:005095330.012
saliva secretionGO:004654130.012
purine ribonucleotide catabolic processGO:00091541360.012
transcription from rna polymerase ii promoterGO:00063662520.012
action potentialGO:0001508540.012
glycosyl compound catabolic processGO:19016581260.012
activation of mapkkk activityGO:000018510.012
negative regulation of catalytic activityGO:00430861030.012
calcium ion transmembrane transportGO:0070588700.012
sulfur compound transportGO:007234880.012
negative regulation of signal transductionGO:0009968830.012
spermatogenesisGO:0007283990.012
liver developmentGO:0001889900.012
cellular ion homeostasisGO:00068731840.012
catecholamine transportGO:0051937370.012
regulation of response to stressGO:00801341260.012
respiratory gaseous exchangeGO:000758540.012
regulation of ossificationGO:0030278320.012
erk1 and erk2 cascadeGO:0070371480.012
peptidyl tyrosine modificationGO:0018212720.012
adult locomotory behaviorGO:000834440.012
purine ribonucleotide biosynthetic processGO:0009152810.012
macromolecule catabolic processGO:0009057580.012
neuromuscular processGO:005090520.012
camera type eye morphogenesisGO:004859320.012
metal ion homeostasisGO:00550651860.012
positive regulation of gamma aminobutyric acid secretionGO:001405440.012
regulation of protein phosphorylationGO:00019321830.012
positive regulation of cellular biosynthetic processGO:00313282950.011
negative regulation of rna biosynthetic processGO:19026791180.011
response to coldGO:0009409290.011
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633930.011
secretion by cellGO:00329402480.011
response to peptideGO:19016522920.011
cognitionGO:0050890920.011
cellular response to nutrient levelsGO:0031669600.011
Yeast
organic cation transportGO:0015695110.011
regulation of nucleotide catabolic processGO:0030811650.011
detection of temperature stimulus involved in sensory perception of painGO:005096540.011
gastrulationGO:000736920.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
peptide transportGO:0015833970.011
intracellular protein transportGO:0006886790.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
regulation of programmed cell deathGO:00430673410.011
myelinationGO:0042552390.011
connective tissue developmentGO:0061448330.011
cellular carbohydrate metabolic processGO:0044262720.011
positive regulation of cellular component organizationGO:00511302000.011
lung developmentGO:0030324430.011

Enpp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.049
nervous system diseaseDOID:86300.049
musculoskeletal system diseaseDOID:1700.027
connective tissue diseaseDOID:6500.027
bone diseaseDOID:008000100.020
sensory system diseaseDOID:005015500.017
eye and adnexa diseaseDOID:149200.017
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.015
eye diseaseDOID:561400.015
bone development diseaseDOID:008000600.014