Rattus norvegicus

3 known processes

Dkc1

dyskeratosis congenita 1, dyskerin

(Aliases: Nap57)

Dkc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.409
regulation of nucleic acid templated transcriptionGO:19035063800.144
regulation of protein metabolic processGO:00512462890.093
rna biosynthetic processGO:00327743800.091
positive regulation of nitrogen compound metabolic processGO:00511733340.082
protein phosphorylationGO:00064683450.077
regulation of molecular functionGO:00650093980.074
negative regulation of macromolecule metabolic processGO:00106052600.070
regulation of rna biosynthetic processGO:20011413810.069
negative regulation of gene expressionGO:00106291990.067
programmed cell deathGO:00125013920.067
negative regulation of metabolic processGO:00098923310.066
negative regulation of cellular metabolic processGO:00313242810.058
regulation of signal transductionGO:00099663180.057
regulation of cellular protein metabolic processGO:00322682670.054
regulation of rna metabolic processGO:00512523910.052
negative regulation of nitrogen compound metabolic processGO:00511721610.052
nucleic acid templated transcriptionGO:00976593790.051
intracellular signal transductionGO:00355563140.050
negative regulation of biosynthetic processGO:00098901680.050
positive regulation of gene expressionGO:00106282440.049
regulation of cell differentiationGO:00455953200.049
transcription dna templatedGO:00063513770.049
regulation of cell proliferationGO:00421273590.047
apoptotic processGO:00069153810.046
response to inorganic substanceGO:00100353770.044
negative regulation of rna metabolic processGO:00512531230.042
negative regulation of cell deathGO:00605482290.042
positive regulation of macromolecule biosynthetic processGO:00105572470.041
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.041
negative regulation of cellular biosynthetic processGO:00313271610.041
regulation of phosphate metabolic processGO:00192203490.041
negative regulation of response to stimulusGO:00485851550.041
locomotionGO:00400112370.039
cell migrationGO:00164771970.039
regulation of multicellular organismal developmentGO:20000263760.039
positive regulation of cell differentiationGO:00455972170.039
catabolic processGO:00090563510.038
positive regulation of cellular biosynthetic processGO:00313282950.038
cellular catabolic processGO:00442482950.037
regulation of blood circulationGO:19035221100.037
cellular response to stressGO:00335542690.037
positive regulation of nucleobase containing compound metabolic processGO:00459353190.037
cell type specific apoptotic processGO:00972851340.037
regulation of transcription from rna polymerase ii promoterGO:00063572340.035
carbohydrate derivative metabolic processGO:19011353460.035
transcription from rna polymerase ii promoterGO:00063662520.034
negative regulation of protein metabolic processGO:00512481140.034
lymphocyte homeostasisGO:000226020.034
regulation of ion transportGO:00432692450.034
regulation of catalytic activityGO:00507903040.034
organelle organizationGO:00069962660.034
positive regulation of biosynthetic processGO:00098913190.033
nucleobase containing small molecule metabolic processGO:00550863160.033
positive regulation of nucleic acid templated transcriptionGO:19035081970.033
regulation of phosphorylationGO:00423252480.032
agingGO:00075682410.031
regenerationGO:00310991630.031
cell motilityGO:00488702020.031
regulation of immunoglobulin productionGO:000263740.029
regulation of transcription dna templatedGO:00063553740.029
cellular response to endogenous stimulusGO:00714953770.029
positive regulation of transcription dna templatedGO:00458931970.029
organic cyclic compound catabolic processGO:19013611750.029
regulation of mrna splicing via spliceosomeGO:004802430.028
regulation of programmed cell deathGO:00430673410.028
negative regulation of nucleobase containing compound metabolic processGO:00459341530.028
regulation of phosphorus metabolic processGO:00511743490.028
positive regulation of nervous system developmentGO:00519621780.027
positive regulation of neurogenesisGO:00507691650.027
regulation of kinase activityGO:00435491170.027
immune responseGO:00069551040.027
response to growth factorGO:00708481890.027
macromolecule localizationGO:00330362520.027
organic substance catabolic processGO:19015753160.027
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.027
rhythmic processGO:00485111560.026
ion homeostasisGO:00508012120.026
organophosphate metabolic processGO:00196373700.026
localization of cellGO:00516742020.026
cellular calcium ion homeostasisGO:00068741600.026
calcium ion homeostasisGO:00550741620.026
positive regulation of rna biosynthetic processGO:19026801970.026
cellular ion homeostasisGO:00068731840.026
cytoplasmic transportGO:00164821150.026
reproductive processGO:00224143720.026
regulation of locomotionGO:00400121480.026
positive regulation of molecular functionGO:00440932300.025
single organism carbohydrate metabolic processGO:00447231180.025
response to bacteriumGO:00096172000.025
cellular response to organonitrogen compoundGO:00714171970.025
protein localizationGO:00081041910.025
single organism intracellular transportGO:19025821660.024
cell projection organizationGO:00300303020.024
positive regulation of multicellular organismal processGO:00512403870.024
response to oxidative stressGO:00069791860.024
positive regulation of cell proliferationGO:00082842490.024
ribonucleotide metabolic processGO:00092592310.024
multi organism reproductive processGO:00447032620.024
aromatic compound catabolic processGO:00194391680.024
mrna metabolic processGO:0016071200.024
purine containing compound metabolic processGO:00725212530.024
cellular divalent inorganic cation homeostasisGO:00725031620.023
intracellular transportGO:00469071850.023
ion transmembrane transportGO:00342203650.023
regulation of apoptotic processGO:00429813350.023
single organism catabolic processGO:00447122830.023
head developmentGO:00603222470.023
amine metabolic processGO:0009308380.023
cellular response to nitrogen compoundGO:19016992100.023
positive regulation of rna metabolic processGO:00512542030.023
regulation of protein modification processGO:00313991940.023
ribonucleoside metabolic processGO:00091191740.023
anterior posterior pattern specificationGO:000995210.023
purine nucleoside metabolic processGO:00422781690.022
regulation of catabolic processGO:00098941130.022
cellular amine metabolic processGO:0044106380.022
multicellular organism reproductionGO:00325042330.022
brain developmentGO:00074202470.022
positive regulation of developmental processGO:00510942830.022
cellular cation homeostasisGO:00300031800.022
purine nucleoside catabolic processGO:00061521240.021
regulation of response to stressGO:00801341260.021
heterocycle catabolic processGO:00467001670.021
cellular amino acid metabolic processGO:00065201070.021
nucleotide metabolic processGO:00091172790.021
regulation of protein phosphorylationGO:00019321830.021
regulation of proteasomal protein catabolic processGO:006113640.021
response to peptide hormoneGO:00434342780.021
transmembrane transportGO:00550854120.021
purine ribonucleotide metabolic processGO:00091502270.021
metal ion transportGO:00300012890.021
response to other organismGO:00517072200.021
regulation of hydrolase activityGO:00513361430.021
positive regulation of cellular amine metabolic processGO:003324030.020
regulation of immune system processGO:00026821230.020
regulation of system processGO:00440572080.020
regulation of cellular catabolic processGO:00313291010.020
nucleoside catabolic processGO:00091641260.020
response to toxic substanceGO:00096361330.020
response to woundingGO:00096112540.020
negative regulation of signal transductionGO:0009968830.020
ribose phosphate metabolic processGO:00196932350.020
g protein coupled receptor signaling pathwayGO:00071862420.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
positive regulation of protein phosphorylationGO:00019341350.020
regulation of cellular amine metabolic processGO:003323880.020
regulation of cellular component movementGO:00512701500.020
oxidation reduction processGO:00551143040.020
negative regulation of cellular protein metabolic processGO:00322691060.020
metal ion homeostasisGO:00550651860.020
negative regulation of molecular functionGO:00440921330.020
regulation of cellular localizationGO:00603412630.019
negative regulation of apoptotic processGO:00430661810.019
homeostatic processGO:00425923310.019
regulation of cellular amino acid metabolic processGO:000652120.019
negative regulation of cell communicationGO:00106481580.019
positive regulation of signalingGO:00230562700.019
purine nucleotide metabolic processGO:00061632290.019
neuron differentiationGO:00301823680.019
regulation of protein kinase activityGO:00458591050.019
response to lipopolysaccharideGO:00324961910.019
positive regulation of cell developmentGO:00107201760.019
chemical homeostasisGO:00488782920.019
negative regulation of transcription dna templatedGO:00458921160.019
cellular nitrogen compound catabolic processGO:00442701630.019
divalent inorganic cation homeostasisGO:00725071650.019
positive regulation of programmed cell deathGO:00430681570.018
embryonic pattern specificationGO:000988010.018
response to biotic stimulusGO:00096072260.018
response to external biotic stimulusGO:00432072210.018
negative regulation of cell differentiationGO:0045596990.018
synaptic growth at neuromuscular junctionGO:005112410.018
nitrogen compound transportGO:00717052290.018
cation transportGO:00068123820.018
response to reactive oxygen speciesGO:00003021200.018
organonitrogen compound catabolic processGO:19015651790.018
cellular homeostasisGO:00197252520.018
secretionGO:00469033070.018
central nervous system developmentGO:00074173110.018
anatomical structure formation involved in morphogenesisGO:0048646830.017
response to hydrogen peroxideGO:0042542890.017
negative regulation of developmental processGO:00510931250.017
regulation of transferase activityGO:00513381230.017
response to ketoneGO:19016541820.017
biological adhesionGO:00226101100.017
regulation of secretion by cellGO:19035302080.017
positive regulation of intracellular signal transductionGO:19025331380.017
cellular metal ion homeostasisGO:00068751720.017
regulation of secretionGO:00510462240.017
gastrulationGO:000736920.017
negative regulation of rna biosynthetic processGO:19026791180.017
cytosolic calcium ion homeostasisGO:00514801400.017
cellular macromolecule localizationGO:00707271220.017
heart morphogenesisGO:000300730.017
nucleoside phosphate metabolic processGO:00067532830.017
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.017
response to oxygen levelsGO:00704822650.017
single organism organelle organizationGO:19025891800.016
ribonucleoside catabolic processGO:00424541260.016
lipid metabolic processGO:00066292830.016
negative regulation of catalytic activityGO:00430861030.016
positive regulation of response to stimulusGO:00485842850.016
regulation of cellular ketone metabolic processGO:0010565270.016
protein transportGO:00150311320.016
response to osmotic stressGO:0006970420.016
single organism reproductive processGO:00447022970.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
positive regulation of cytosolic calcium ion concentrationGO:00072041220.016
positive regulation of apoptotic processGO:00430651540.016
circulatory system developmentGO:00723591340.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
negative regulation of programmed cell deathGO:00430691830.016
positive regulation of protein metabolic processGO:00512471780.016
oxoacid metabolic processGO:00434362900.016
neuron developmentGO:00486662860.016
purine ribonucleoside metabolic processGO:00461281680.016
peptidyl amino acid modificationGO:00181931260.016
protein localization to organelleGO:0033365570.016
regulation of neurogenesisGO:00507672470.015
positive regulation of cellular component organizationGO:00511302000.015
protein autophosphorylationGO:0046777660.015
positive regulation of cellular protein metabolic processGO:00322701670.015
nucleobase containing compound catabolic processGO:00346551520.015
hematopoietic progenitor cell differentiationGO:000224420.015
cellular ketone metabolic processGO:0042180510.015
organic acid metabolic processGO:00060822920.015
cardiovascular system developmentGO:00723581340.015
cellular component assemblyGO:00226073600.015
regulation of nervous system developmentGO:00519602640.015
regulation of cell motilityGO:20001451310.015
neuron deathGO:00709971270.015
cellular response to abiotic stimulusGO:0071214850.015
axis specificationGO:000979840.015
neuron projection developmentGO:00311752730.014
positive regulation of secretion by cellGO:19035321280.014
regulation of cell developmentGO:00602842630.014
cellular chemical homeostasisGO:00550822470.014
heart processGO:0003015570.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
reproductionGO:00000032450.014
negative regulation of immune system processGO:0002683390.014
negative regulation of signalingGO:00230571570.014
muscle system processGO:00030121150.014
regulation of canonical wnt signaling pathwayGO:006082840.014
macromolecular complex assemblyGO:00650032730.014
cell growthGO:00160491040.014
carbohydrate metabolic processGO:00059751300.014
learning or memoryGO:0007611900.014
response to decreased oxygen levelsGO:00362932370.014
mechanoreceptor differentiationGO:004249020.014
secretion by cellGO:00329402480.013
sexual reproductionGO:00199531480.013
insulin like growth factor receptor signaling pathwayGO:004800930.013
response to mechanical stimulusGO:00096121340.013
carboxylic acid metabolic processGO:00197522890.013
response to acid chemicalGO:00011012220.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
anatomical structure morphogenesisGO:00096532980.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
multicellular organismal reproductive processGO:00486092330.013
positive regulation of phosphorylationGO:00423271770.013
nuclear importGO:0051170350.013
response to peptideGO:19016522920.013
immune system developmentGO:0002520410.013
macromolecular complex subunit organizationGO:00439333390.013
heart developmentGO:0007507720.013
dna integrity checkpointGO:003157020.013
positive regulation of secretionGO:00510471400.013
regulation of cell cycleGO:0051726730.013
epithelium developmentGO:0060429960.013
leukocyte activationGO:0045321760.013
defense responseGO:00069521940.013
cellular response to peptideGO:19016531330.013
reactive nitrogen species metabolic processGO:200105710.013
hematopoietic or lymphoid organ developmentGO:0048534360.013
proteolysisGO:00065081750.012
small gtpase mediated signal transductionGO:0007264360.012
wound healingGO:00420601220.012
reactive oxygen species metabolic processGO:0072593370.012
cell activationGO:0001775970.012
positive regulation of neuron differentiationGO:00456661260.012
cellular response to organic cyclic compoundGO:00714072020.012
cellular response to growth factor stimulusGO:00713631620.012
regulation of cell migrationGO:00303341280.012
positive regulation of phosphorus metabolic processGO:00105622620.012
negative regulation of protein phosphorylationGO:0001933440.012
glycosyl compound metabolic processGO:19016571820.012
positive regulation of cellular component movementGO:00512721020.012
nucleoside metabolic processGO:00091161790.012
positive regulation of catalytic activityGO:00430851840.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
lipid biosynthetic processGO:00086101280.012
negative regulation of protein modification processGO:0031400520.012
developmental process involved in reproductionGO:00030061590.012
negative regulation of phosphate metabolic processGO:0045936800.012
regulation of neuron projection developmentGO:00109751610.012
cellular lipid metabolic processGO:00442552080.012
gonad developmentGO:00084061040.012
positive regulation of cell communicationGO:00106472710.012
histone modificationGO:0016570300.011
positive regulation of transportGO:00510502450.011
negative regulation of phosphorus metabolic processGO:0010563800.011
response to campGO:0051591910.011
somatic stem cell divisionGO:004810320.011
regulation of metal ion transportGO:00109591180.011
cell cycle checkpointGO:000007520.011
immune system processGO:00023762040.011
heart contractionGO:0060047570.011
purine containing compound catabolic processGO:00725231380.011
cellular component movementGO:00069282480.011
carbohydrate derivative catabolic processGO:19011361470.011
positive regulation of immune responseGO:0050778420.011
regulation of neuron deathGO:19012141150.011
regulation of intracellular signal transductionGO:19025312180.011
response to extracellular stimulusGO:00099913800.011
cell cycleGO:00070491010.011
negative regulation of cell cycle phase transitionGO:190198840.011
regulation of immune responseGO:0050776550.011
regulation of homeostatic processGO:00328441010.011
blood circulationGO:00080151830.011
purine nucleotide catabolic processGO:00061951360.011
single organism biosynthetic processGO:00447113420.011
negative regulation of neuron deathGO:1901215690.011
regulation of heart contractionGO:0008016480.011
cell adhesionGO:00071551100.010
dna metabolic processGO:0006259960.010
positive regulation of neuron projection developmentGO:0010976990.010
reactive oxygen species biosynthetic processGO:190340980.010
negative regulation of cell proliferationGO:00082851190.010
organophosphate catabolic processGO:00464341480.010
chromosome segregationGO:000705920.010
activation of cysteine type endopeptidase activityGO:009720240.010
cellular response to oxygen containing compoundGO:19017013860.010
establishment of protein localizationGO:00451841410.010
protein heterooligomerizationGO:0051291890.010
gamete generationGO:00072761240.010
artery developmentGO:006084030.010
negative regulation of phosphorylationGO:0042326570.010
lymphocyte activationGO:0046649430.010
regulation of cell activationGO:0050865500.010
dna damage checkpointGO:000007720.010
regulation of anatomical structure morphogenesisGO:00226031410.010

Dkc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
intestinal cancerDOID:1015500.016
gastrointestinal system cancerDOID:311900.016
cancerDOID:16200.016
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.016
central nervous system diseaseDOID:33100.012