IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Trat1

T cell receptor associated transmembrane adaptor 1

(Aliases: MGC125004)

Entrez: 498075
Ensembl: ENSRNOG00000029564
RGD: 1563011
UniProtKB: Q2TA64

Process Predictions
Disease Predictions

Trat1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of metabolic process	GO:0009892	331	0.061
response to biotic stimulus	GO:0009607	226	0.051
positive regulation of cell proliferation	GO:0008284	249	0.049
response to extracellular stimulus	GO:0009991	380	0.048
negative regulation of cellular metabolic process	GO:0031324	281	0.048
regulation of cell proliferation	GO:0042127	359	0.047
programmed cell death	GO:0012501	392	0.047
multi organism reproductive process	GO:0044703	262	0.042
response to nutrient levels	GO:0031667	370	0.040
apoptotic process	GO:0006915	381	0.040
negative regulation of macromolecule metabolic process	GO:0010605	260	0.040
response to oxygen levels	GO:0070482	265	0.038
regulation of catalytic activity	GO:0050790	304	0.037
regulation of programmed cell death	GO:0043067	341	0.035
cellular response to oxygen containing compound	GO:1901701	386	0.035
regulation of rna biosynthetic process	GO:2001141	381	0.034
immune system process	GO:0002376	204	0.033
regulation of cell differentiation	GO:0045595	320	0.032
response to inorganic substance	GO:0010035	377	0.032
negative regulation of cell death	GO:0060548	229	0.031
response to bacterium	GO:0009617	200	0.031
defense response	GO:0006952	194	0.031
response to hypoxia	GO:0001666	231	0.031
positive regulation of multicellular organismal process	GO:0051240	387	0.030
secretion	GO:0046903	307	0.029
negative regulation of gene expression	GO:0010629	199	0.029
response to cytokine	GO:0034097	215	0.028
response to peptide	GO:1901652	292	0.028
regulation of molecular function	GO:0065009	398	0.028
response to lipopolysaccharide	GO:0032496	191	0.027
nucleic acid templated transcription	GO:0097659	379	0.027
reproductive process	GO:0022414	372	0.027
regulation of nucleic acid templated transcription	GO:1903506	380	0.026
cellular response to endogenous stimulus	GO:0071495	377	0.026
multi multicellular organism process	GO:0044706	138	0.025
catabolic process	GO:0009056	351	0.025
proteolysis	GO:0006508	175	0.024
single organism biosynthetic process	GO:0044711	342	0.024
regulation of apoptotic process	GO:0042981	335	0.024
positive regulation of cell differentiation	GO:0045597	217	0.024
protein phosphorylation	GO:0006468	345	0.024
regulation of phosphorus metabolic process	GO:0051174	349	0.023
regulation of transcription dna templated	GO:0006355	374	0.022
regulation of protein metabolic process	GO:0051246	289	0.022
regulation of cellular component organization	GO:0051128	368	0.022
response to peptide hormone	GO:0043434	278	0.022
regulation of rna metabolic process	GO:0051252	391	0.021
rna biosynthetic process	GO:0032774	380	0.021
transcription dna templated	GO:0006351	377	0.021
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.021
regulation of multicellular organismal development	GO:2000026	376	0.021
positive regulation of response to stimulus	GO:0048584	285	0.021
intracellular signal transduction	GO:0035556	314	0.021
negative regulation of protein metabolic process	GO:0051248	114	0.021
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.021
homeostatic process	GO:0042592	331	0.020
cellular amine metabolic process	GO:0044106	38	0.020
single organism intracellular transport	GO:1902582	166	0.020
regulation of secretion	GO:0051046	224	0.020
multicellular organismal reproductive process	GO:0048609	233	0.020
secretion by cell	GO:0032940	248	0.020
negative regulation of biosynthetic process	GO:0009890	168	0.020
positive regulation of biosynthetic process	GO:0009891	319	0.020
multicellular organism reproduction	GO:0032504	233	0.019
regulation of cellular amino acid metabolic process	GO:0006521	2	0.019
behavior	GO:0007610	205	0.019
response to insulin	GO:0032868	133	0.019
lipid metabolic process	GO:0006629	283	0.019
regulation of hormone levels	GO:0010817	187	0.019
regulation of blood vessel size	GO:0050880	89	0.019
anatomical structure morphogenesis	GO:0009653	298	0.019
cellular response to cytokine stimulus	GO:0071345	127	0.019
response to other organism	GO:0051707	220	0.019
response to external biotic stimulus	GO:0043207	221	0.019
negative regulation of apoptotic process	GO:0043066	181	0.019
growth	GO:0040007	165	0.018
regulation of cellular ketone metabolic process	GO:0010565	27	0.018
positive regulation of molecular function	GO:0044093	230	0.018
inflammatory response	GO:0006954	150	0.018
regulation of phosphate metabolic process	GO:0019220	349	0.018
rna metabolic process	GO:0016070	406	0.018
response to decreased oxygen levels	GO:0036293	237	0.018
circadian rhythm	GO:0007623	88	0.018
regulation of cellular amine metabolic process	GO:0033238	8	0.018
vascular process in circulatory system	GO:0003018	96	0.018
positive regulation of cellular biosynthetic process	GO:0031328	295	0.018
positive regulation of apoptotic process	GO:0043065	154	0.018
carboxylic acid metabolic process	GO:0019752	289	0.018
metal ion transport	GO:0030001	289	0.018
positive regulation of catalytic activity	GO:0043085	184	0.018
immunoglobulin mediated immune response	GO:0016064	4	0.017
response to wounding	GO:0009611	254	0.017
single organism reproductive process	GO:0044702	297	0.017
response to carbohydrate	GO:0009743	183	0.017
positive regulation of cell death	GO:0010942	184	0.017
organic substance catabolic process	GO:1901575	316	0.017
steroid metabolic process	GO:0008202	73	0.017
oxoacid metabolic process	GO:0043436	290	0.017
neurological system process	GO:0050877	219	0.017
cellular chemical homeostasis	GO:0055082	247	0.017
nucleobase containing small molecule metabolic process	GO:0055086	316	0.017
regulation of signal transduction	GO:0009966	318	0.016
protein complex biogenesis	GO:0070271	263	0.016
positive regulation of transport	GO:0051050	245	0.016
cellular ketone metabolic process	GO:0042180	51	0.016
positive regulation of developmental process	GO:0051094	283	0.016
rhythmic process	GO:0048511	156	0.016
negative regulation of cellular biosynthetic process	GO:0031327	161	0.016
regulation of cellular localization	GO:0060341	263	0.015
response to molecule of bacterial origin	GO:0002237	194	0.015
organic acid metabolic process	GO:0006082	292	0.015
negative regulation of cellular protein metabolic process	GO:0032269	106	0.015
macromolecule localization	GO:0033036	252	0.015
chemical homeostasis	GO:0048878	292	0.015
cell growth	GO:0016049	104	0.015
response to oxidative stress	GO:0006979	186	0.015
hepaticobiliary system development	GO:0061008	90	0.015
positive regulation of signaling	GO:0023056	270	0.015
protein complex assembly	GO:0006461	263	0.015
cellular homeostasis	GO:0019725	252	0.015
carbohydrate derivative metabolic process	GO:1901135	346	0.015
negative regulation of response to stimulus	GO:0048585	155	0.015
positive regulation of cellular amine metabolic process	GO:0033240	3	0.014
ion homeostasis	GO:0050801	212	0.014
regulation of locomotion	GO:0040012	148	0.014
regulation of membrane potential	GO:0042391	110	0.014
circulatory system process	GO:0003013	183	0.014
regulation of immune response	GO:0050776	55	0.014
protein heterooligomerization	GO:0051291	89	0.014
regulation of phosphorylation	GO:0042325	248	0.014
negative regulation of catalytic activity	GO:0043086	103	0.014
negative regulation of protein maturation	GO:1903318	47	0.014
positive regulation of phosphorylation	GO:0042327	177	0.014
regulation of reactive oxygen species metabolic process	GO:2000377	26	0.014
blood circulation	GO:0008015	183	0.014
regulation of cell development	GO:0060284	263	0.014
ras protein signal transduction	GO:0007265	29	0.014
regulation of protein processing	GO:0070613	50	0.014
neuron death	GO:0070997	127	0.014
neuron differentiation	GO:0030182	368	0.014
cation transport	GO:0006812	382	0.014
regulation of neurogenesis	GO:0050767	247	0.013
brain development	GO:0007420	247	0.013
positive regulation of cellular component organization	GO:0051130	200	0.013
muscle system process	GO:0003012	115	0.013
macromolecular complex assembly	GO:0065003	273	0.013
regulation of protein maturation	GO:1903317	50	0.013
protein maturation	GO:0051604	68	0.013
head development	GO:0060322	247	0.013
reactive nitrogen species metabolic process	GO:2001057	1	0.013
leukocyte activation	GO:0045321	76	0.013
negative regulation of developmental process	GO:0051093	125	0.013
positive regulation of protein modification process	GO:0031401	142	0.013
negative regulation of programmed cell death	GO:0043069	183	0.013
regulation of mesenchymal cell proliferation	GO:0010464	4	0.013
response to tumor cell	GO:0002347	4	0.013
biological adhesion	GO:0022610	110	0.013
neuron development	GO:0048666	286	0.013
cellular component biogenesis	GO:0044085	368	0.013
action potential	GO:0001508	54	0.013
liver development	GO:0001889	90	0.013
detection of chemical stimulus involved in sensory perception of bitter taste	GO:0001580	4	0.013
cellular cation homeostasis	GO:0030003	180	0.013
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.013
regulation of tube size	GO:0035150	89	0.013
neuron projection development	GO:0031175	273	0.013
regulation of hydrolase activity	GO:0051336	143	0.012
regulation of reactive oxygen species biosynthetic process	GO:1903426	5	0.012
jak stat cascade	GO:0007259	26	0.012
protein processing	GO:0016485	68	0.012
response to reactive oxygen species	GO:0000302	120	0.012
central nervous system development	GO:0007417	311	0.012
protein oligomerization	GO:0051259	191	0.012
ribonucleotide metabolic process	GO:0009259	231	0.012
response to ethanol	GO:0045471	162	0.012
transcription from rna polymerase ii promoter	GO:0006366	252	0.012
nucleotide metabolic process	GO:0009117	279	0.012
metal ion homeostasis	GO:0055065	186	0.012
mesenchymal cell proliferation	GO:0010463	4	0.012
cellular response to stress	GO:0033554	269	0.012
single organism organelle organization	GO:1902589	180	0.012
regulation of protein kinase activity	GO:0045859	105	0.012
reactive oxygen species biosynthetic process	GO:1903409	8	0.012
positive regulation of immunoglobulin mediated immune response	GO:0002891	2	0.012
positive regulation of gene expression	GO:0010628	244	0.012
positive regulation of nervous system development	GO:0051962	178	0.012
cell projection organization	GO:0030030	302	0.012
positive regulation of cellular protein metabolic process	GO:0032270	167	0.012
response to acid chemical	GO:0001101	222	0.012
regulation of transferase activity	GO:0051338	123	0.012
carbohydrate metabolic process	GO:0005975	130	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.012
small gtpase mediated signal transduction	GO:0007264	36	0.012
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.012
cell adhesion	GO:0007155	110	0.012
response to nutrient	GO:0007584	248	0.011
positive regulation of phosphorus metabolic process	GO:0010562	262	0.011
cellular response to lipid	GO:0071396	201	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.011
cellular amino acid metabolic process	GO:0006520	107	0.011
sensory perception of bitter taste	GO:0050913	4	0.011
regulation of cell projection organization	GO:0031344	175	0.011
cell activation	GO:0001775	97	0.011
regulation of growth	GO:0040008	105	0.011
amine metabolic process	GO:0009308	38	0.011
reproduction	GO:0000003	245	0.011
aging	GO:0007568	241	0.011
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.011
response to metal ion	GO:0010038	253	0.011
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.011
spermatogenesis	GO:0007283	99	0.011
cellular component assembly	GO:0022607	360	0.011
regulation of protein phosphorylation	GO:0001932	183	0.011
regulation of neuron death	GO:1901214	115	0.011
regulation of body fluid levels	GO:0050878	90	0.011
positive regulation of immune system process	GO:0002684	90	0.011
negative regulation of rna biosynthetic process	GO:1902679	118	0.011
cell cycle checkpoint	GO:0000075	2	0.011
positive regulation of protein metabolic process	GO:0051247	178	0.011
organelle organization	GO:0006996	266	0.011
intracellular transport	GO:0046907	185	0.011
cell type specific apoptotic process	GO:0097285	134	0.011
lymphocyte activation	GO:0046649	43	0.011
regulation of immune system process	GO:0002682	123	0.011
regulation of immunoglobulin mediated immune response	GO:0002889	2	0.010
peptidyl amino acid modification	GO:0018193	126	0.010
lipid biosynthetic process	GO:0008610	128	0.010
positive regulation of isotype switching	GO:0045830	1	0.010
regulation of proteasomal protein catabolic process	GO:0061136	4	0.010
male gamete generation	GO:0048232	99	0.010
regulation of cellular protein metabolic process	GO:0032268	267	0.010
response to estradiol	GO:0032355	164	0.010
single organism carbohydrate metabolic process	GO:0044723	118	0.010
transmission of nerve impulse	GO:0019226	42	0.010
purine containing compound metabolic process	GO:0072521	253	0.010
b cell activation involved in immune response	GO:0002312	1	0.010
positive regulation of neurogenesis	GO:0050769	165	0.010
positive regulation of cell communication	GO:0010647	271	0.010
negative regulation of secretion by cell	GO:1903531	72	0.010
response to estrogen	GO:0043627	232	0.010

Trat1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	nervous system disease	DOID:863	0	0.016
	disease of anatomical entity	DOID:7	0	0.016

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