Rattus norvegicus

65 known processes

Gfra2

GDNF family receptor alpha 2

(Aliases: Retl2)

Gfra2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transmembrane transportGO:00986552630.886
transmembrane transportGO:00550854120.871
neurological system processGO:00508772190.820
cation transportGO:00068123820.816
monovalent inorganic cation transportGO:00156721720.775
nitrogen compound transportGO:00717052290.752
inorganic ion transmembrane transportGO:00986602290.727
regulation of secretionGO:00510462240.721
inorganic cation transmembrane transportGO:00986622020.699
g protein coupled receptor signaling pathwayGO:00071862420.644
synaptic transmissionGO:00072682350.630
learning or memoryGO:0007611900.620
ion transmembrane transportGO:00342203650.599
regulation of secretion by cellGO:19035302080.538
regulation of ion transportGO:00432692450.506
regulation of phosphorus metabolic processGO:00511743490.494
positive regulation of secretion by cellGO:19035321280.490
intracellular signal transductionGO:00355563140.436
regulation of signal transductionGO:00099663180.387
cellular ion homeostasisGO:00068731840.381
cellular response to organic cyclic compoundGO:00714072020.379
metal ion transportGO:00300012890.361
action potentialGO:0001508540.348
macromolecular complex subunit organizationGO:00439333390.337
muscle system processGO:00030121150.327
locomotionGO:00400112370.327
Rat
positive regulation of secretionGO:00510471400.326
positive regulation of protein phosphorylationGO:00019341350.325
single organism behaviorGO:00447081300.318
signal transduction by phosphorylationGO:00230141440.315
cognitionGO:0050890920.311
divalent inorganic cation homeostasisGO:00725071650.309
positive regulation of transportGO:00510502450.300
secretion by cellGO:00329402480.297
cellular component assemblyGO:00226073600.272
neuron neuron synaptic transmissionGO:0007270600.268
smooth muscle contractionGO:0006939370.262
regulation of cellular localizationGO:00603412630.261
cation homeostasisGO:00550801950.258
regulation of membrane potentialGO:00423911100.254
response to inorganic substanceGO:00100353770.254
mapk cascadeGO:00001651400.247
potassium ion transportGO:0006813970.245
carbohydrate metabolic processGO:00059751300.245
regulation of system processGO:00440572080.245
response to ammonium ionGO:0060359710.244
tissue developmentGO:00098882520.241
response to alkaloidGO:00432791320.239
cellular component biogenesisGO:00440853680.238
cellular calcium ion homeostasisGO:00068741600.238
cell cell signalingGO:00072673350.233
regulation of phosphate metabolic processGO:00192203490.233
regulation of multicellular organismal developmentGO:20000263760.230
protein localizationGO:00081041910.228
response to ethanolGO:00454711620.218
positive regulation of signalingGO:00230562700.217
protein phosphorylationGO:00064683450.209
blood circulationGO:00080151830.209
single organism cellular localizationGO:19025801020.208
regulation of phosphorylationGO:00423252480.204
regulation of neuronal synaptic plasticityGO:0048168310.201
macromolecular complex assemblyGO:00650032730.197
vascular process in circulatory systemGO:0003018960.196
regulation of protein modification processGO:00313991940.195
cellular chemical homeostasisGO:00550822470.193
neuromuscular synaptic transmissionGO:000727420.191
homeostatic processGO:00425923310.189
feeding behaviorGO:0007631530.187
cellular cation homeostasisGO:00300031800.182
protein autophosphorylationGO:0046777660.182
organophosphate metabolic processGO:00196373700.178
behaviorGO:00076102050.178
circulatory system processGO:00030131830.178
regulation of cellular component organizationGO:00511283680.177
protein complex subunit organizationGO:00718223020.172
cellular response to lipidGO:00713962010.170
regulation of intracellular signal transductionGO:19025312180.165
ion homeostasisGO:00508012120.161
response to decreased oxygen levelsGO:00362932370.160
macromolecule localizationGO:00330362520.158
positive regulation of signal transductionGO:00099671750.156
anion transportGO:00068201780.155
regulation of organelle organizationGO:0033043800.152
secretionGO:00469033070.149
metal ion homeostasisGO:00550651860.148
regulation of cellular amine metabolic processGO:003323880.147
immune system processGO:00023762040.143
response to cocaineGO:0042220390.143
organic hydroxy compound metabolic processGO:19016151150.143
synaptic transmission cholinergicGO:0007271110.143
circulatory system developmentGO:00723591340.136
regulation of molecular functionGO:00650093980.135
learningGO:0007612330.133
regulation of cell differentiationGO:00455953200.132
brain developmentGO:00074202470.132
response to oxygen levelsGO:00704822650.127
regulation of neuron differentiationGO:00456642080.125
negative regulation of signalingGO:00230571570.125
central nervous system developmentGO:00074173110.122
positive regulation of phosphorylationGO:00423271770.121
oxoacid metabolic processGO:00434362900.121
regulation of protein metabolic processGO:00512462890.118
regulation of muscle system processGO:0090257790.118
glycerolipid metabolic processGO:0046486670.117
divalent metal ion transportGO:00708381320.117
anatomical structure morphogenesisGO:00096532980.117
cellular protein localizationGO:00346131220.116
neuron apoptotic processGO:0051402880.116
transcription from rna polymerase ii promoterGO:00063662520.116
head developmentGO:00603222470.115
protein transportGO:00150311320.115
neuron developmentGO:00486662860.113
Rat
regulation of ion transmembrane transportGO:00347651210.112
regulation of transcription dna templatedGO:00063553740.110
regulation of rna metabolic processGO:00512523910.108
cardiovascular system developmentGO:00723581340.108
positive regulation of synaptic transmissionGO:0050806620.106
cytosolic calcium ion homeostasisGO:00514801400.106
regulation of action potentialGO:0098900140.106
response to cytokineGO:00340972150.105
positive regulation of phosphate metabolic processGO:00459372620.105
rhythmic processGO:00485111560.104
positive regulation of protein modification processGO:00314011420.104
cellular response to organonitrogen compoundGO:00714171970.104
regulation of hormone secretionGO:00468831060.103
amino acid transportGO:0006865700.103
regulation of blood circulationGO:19035221100.101
response to estradiolGO:00323551640.101
cellular potassium ion transportGO:0071804720.100
protein complex assemblyGO:00064612630.100
regulation of metal ion transportGO:00109591180.100
synaptic transmission gabaergicGO:0051932220.099
regulation of muscle contractionGO:0006937530.098
cellular divalent inorganic cation homeostasisGO:00725031620.098
transcription dna templatedGO:00063513770.098
immune responseGO:00069551040.097
protein heterooligomerizationGO:0051291890.097
regulation of cell developmentGO:00602842630.097
response to calcium ionGO:0051592590.097
regulation of transmembrane transportGO:00347621220.097
positive regulation of cell communicationGO:00106472710.095
organic hydroxy compound transportGO:0015850770.094
regulation of hormone levelsGO:00108171870.094
cellular metal ion homeostasisGO:00068751720.093
lymphocyte activationGO:0046649430.093
regulation of neurogenesisGO:00507672470.093
second messenger mediated signalingGO:0019932510.092
calcium ion homeostasisGO:00550741620.092
rna biosynthetic processGO:00327743800.092
defense responseGO:00069521940.092
response to metal ionGO:00100382530.092
regulation of leukocyte activationGO:0002694450.092
chemical homeostasisGO:00488782920.091
choline transportGO:001587140.091
inflammatory responseGO:00069541500.089
regulation of catalytic activityGO:00507903040.089
regulation of neuron apoptotic processGO:0043523830.089
response to mechanical stimulusGO:00096121340.088
cellular amino acid metabolic processGO:00065201070.088
negative regulation of multicellular organismal processGO:00512412030.087
positive regulation of mapk cascadeGO:0043410920.085
regulation of catecholamine secretionGO:0050433320.084
negative regulation of neuron differentiationGO:0045665620.083
divalent inorganic cation transportGO:00725111340.082
amine transportGO:0015837570.082
response to ketoneGO:19016541820.082
developmental growthGO:00485891000.081
calcium ion transportGO:00068161310.081
salivary gland morphogenesisGO:000743510.080
telencephalon developmentGO:0021537620.080
adult locomotory behaviorGO:000834440.079
rna metabolic processGO:00160704060.079
potassium ion transmembrane transportGO:0071805710.079
response to nicotineGO:0035094510.077
cellular response to oxygen containing compoundGO:19017013860.077
phospholipid metabolic processGO:0006644610.076
response to purine containing compoundGO:00140741260.076
apoptotic processGO:00069153810.076
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.075
regulation of peptide transportGO:0090087870.075
camp metabolic processGO:0046058630.075
muscle structure developmentGO:0061061870.074
regulation of protein phosphorylationGO:00019321830.074
regulation of amine transportGO:0051952540.074
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.074
sensory perceptionGO:00076001010.072
positive regulation of molecular functionGO:00440932300.070
protein oligomerizationGO:00512591910.069
regulation of blood vessel sizeGO:0050880890.068
single organism catabolic processGO:00447122830.068
regulation of ion transmembrane transporter activityGO:0032412480.067
biological adhesionGO:00226101100.067
regulation of nervous system developmentGO:00519602640.067
response to estrogenGO:00436272320.067
amine metabolic processGO:0009308380.066
sodium ion transmembrane transportGO:0035725670.066
regulation of locomotionGO:00400121480.066
positive regulation of cell proliferationGO:00082842490.065
cellular component morphogenesisGO:00329891550.065
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189240.065
positive regulation of developmental processGO:00510942830.064
negative regulation of cell communicationGO:00106481580.063
agingGO:00075682410.063
Rat
response to acid chemicalGO:00011012220.063
positive regulation of cellular protein metabolic processGO:00322701670.062
reproductive processGO:00224143720.062
Rat
monoamine transportGO:0015844430.062
regulation of heart contractionGO:0008016480.062
cellular response to cytokine stimulusGO:00713451270.061
regulation of rna biosynthetic processGO:20011413810.061
multi organism reproductive processGO:00447032620.060
regulation of homeostatic processGO:00328441010.060
alcohol metabolic processGO:0006066770.060
calcium ion importGO:0070509220.060
positive regulation of cell developmentGO:00107201760.059
response to extracellular stimulusGO:00099913800.059
erk1 and erk2 cascadeGO:0070371480.059
single organism intracellular transportGO:19025821660.059
regulation of transporter activityGO:0032409500.058
positive regulation of cell activationGO:0050867340.058
cellular homeostasisGO:00197252520.058
leukocyte activationGO:0045321760.058
negative regulation of metabolic processGO:00098923310.057
regulation of organ formationGO:000315620.057
positive regulation of heart contractionGO:0045823150.057
cell projection organizationGO:00300303020.056
Rat
positive regulation of cell deathGO:00109421840.056
intracellular transportGO:00469071850.056
multicellular organism reproductionGO:00325042330.055
muscle contractionGO:0006936880.055
limbic system developmentGO:0021761380.055
regulation of apoptotic processGO:00429813350.054
positive regulation of ion transportGO:0043270940.054
positive regulation of gene expressionGO:00106282440.054
negative regulation of ion transportGO:0043271510.054
regulation of tube sizeGO:0035150890.053
carboxylic acid metabolic processGO:00197522890.053
response to woundingGO:00096112540.053
single organism carbohydrate metabolic processGO:00447231180.052
positive regulation of intracellular signal transductionGO:19025331380.052
developmental process involved in reproductionGO:00030061590.051
Rat
positive regulation of myeloid leukocyte differentiationGO:000276370.051
positive regulation of immune system processGO:0002684900.051
positive regulation of response to stimulusGO:00485842850.051
regulation of transmembrane transporter activityGO:0022898490.051
positive regulation of protein kinase activityGO:0045860730.051
organic cyclic compound catabolic processGO:19013611750.050
positive regulation of phosphorus metabolic processGO:00105622620.050
organic acid metabolic processGO:00060822920.050
motor neuron axon guidanceGO:000804510.050
cell part morphogenesisGO:00329901230.049
purine containing compound metabolic processGO:00725212530.049
memoryGO:0007613540.049
regulation of immune system processGO:00026821230.049
muscle tissue developmentGO:0060537580.048
regulation of synaptic transmissionGO:00508041410.048
sensory perception of painGO:0019233730.048
cellular amine metabolic processGO:0044106380.048
synaptic transmission glutamatergicGO:0035249330.047
positive regulation of cytosolic calcium ion concentrationGO:00072041220.047
nucleobase containing small molecule metabolic processGO:00550863160.047
nucleic acid templated transcriptionGO:00976593790.046
sexual reproductionGO:00199531480.046
transmission of nerve impulseGO:0019226420.046
cyclic nucleotide metabolic processGO:0009187800.046
negative regulation of transportGO:00510511360.045
cellular response to endogenous stimulusGO:00714953770.045
activation of protein kinase activityGO:0032147470.045
response to nutrient levelsGO:00316673700.045
protein localization to membraneGO:0072657360.044
cell motilityGO:00488702020.044
Rat
regulation of anatomical structure sizeGO:00900661350.044
negative regulation of response to stimulusGO:00485851550.044
protein complex biogenesisGO:00702712630.044
carbohydrate derivative metabolic processGO:19011353460.044
cellular macromolecule localizationGO:00707271220.043
small molecule biosynthetic processGO:00442831240.043
glycerophospholipid metabolic processGO:0006650470.043
single organism biosynthetic processGO:00447113420.043
regulation of programmed cell deathGO:00430673410.042
calcium ion transmembrane transportGO:0070588700.042
lipid metabolic processGO:00066292830.042
regulation of actin filament based processGO:0032970420.042
behavioral response to nicotineGO:003509520.042
positive regulation of erk1 and erk2 cascadeGO:0070374290.041
saliva secretionGO:004654130.041
regulation of feeding behaviorGO:0060259140.041
carboxylic acid transportGO:00469421150.041
cell adhesionGO:00071551100.040
myeloid leukocyte differentiationGO:0002573200.040
neuron projection developmentGO:00311752730.040
Rat
heart developmentGO:0007507720.040
positive regulation of multicellular organismal processGO:00512403870.040
regulation of kinase activityGO:00435491170.039
heart contractionGO:0060047570.039
camp biosynthetic processGO:0006171470.039
regulation of cation channel activityGO:2001257230.039
cellular component movementGO:00069282480.039
Rat
response to corticosteroidGO:00319602350.039
regulation of sensory perception of painGO:0051930290.038
cellular response to stressGO:00335542690.038
long term synaptic potentiationGO:0060291210.038
negative regulation of ion transmembrane transportGO:0034766160.038
regulation of sensory perceptionGO:0051931290.037
organic acid transportGO:00158491160.037
vesicle mediated transportGO:00161921810.037
regulation of synaptic plasticityGO:0048167700.037
forebrain developmentGO:0030900980.037
positive regulation of transferase activityGO:0051347810.037
response to toxic substanceGO:00096361330.037
organophosphate biosynthetic processGO:00904071430.037
hormone transportGO:00099141210.037
cellular carbohydrate metabolic processGO:0044262720.037
establishment of protein localizationGO:00451841410.037
cellular lipid metabolic processGO:00442552080.036
peptide transportGO:0015833970.036
pallium developmentGO:0021543420.036
response to external biotic stimulusGO:00432072210.036
adult behaviorGO:0030534160.036
gonad developmentGO:00084061040.035
Rat
single organism reproductive processGO:00447022970.035
Rat
regulation of cell proliferationGO:00421273590.035
cellular response to nitrogen compoundGO:19016992100.035
purine containing compound catabolic processGO:00725231380.034
regulation of cellular ketone metabolic processGO:0010565270.034
somatic stem cell divisionGO:004810320.034
immune effector processGO:0002252530.034
multicellular organismal signalingGO:0035637440.034
actin filament based processGO:0030029860.034
positive regulation of leukocyte proliferationGO:0070665200.033
cytoskeleton organizationGO:00070101110.033
regulation of nucleic acid templated transcriptionGO:19035063800.033
intracellular receptor signaling pathwayGO:0030522350.033
regulation of adenylate cyclase activityGO:0045761180.033
regulation of protein kinase activityGO:00458591050.032
circadian rhythmGO:0007623880.032
regulation of cellular protein metabolic processGO:00322682670.032
positive regulation of nervous system developmentGO:00519621780.032
catabolic processGO:00090563510.032
regulation of anatomical structure morphogenesisGO:00226031410.032
negative regulation of cell developmentGO:0010721820.032
blood vessel developmentGO:0001568690.032
regulation of blood pressureGO:0008217830.032
regulation of calcium ion transportGO:0051924770.032
calcium ion transport into cytosolGO:0060402380.032
positive regulation of protein metabolic processGO:00512471780.031
response to light stimulusGO:0009416520.031
response to hydrogen peroxideGO:0042542890.031
glutamate secretionGO:0014047190.031
reproductive structure developmentGO:00486081280.031
Rat
response to organophosphorusGO:00466831020.030
purine nucleotide catabolic processGO:00061951360.030
neuron differentiationGO:00301823680.030
Rat
cell type specific apoptotic processGO:00972851340.030
negative regulation of signal transductionGO:0009968830.030
positive regulation of mast cell activationGO:003300540.030
single organism membrane organizationGO:0044802740.030
positive regulation of action potentialGO:004576080.029
nucleoside phosphate metabolic processGO:00067532830.029
reproductionGO:00000032450.029
multicellular organismal reproductive processGO:00486092330.029
response to other organismGO:00517072200.029
positive regulation of leukocyte activationGO:0002696300.029
cell morphogenesisGO:00009021420.029
actin filament organizationGO:0007015420.028
regulation of cellular component movementGO:00512701500.028
serotonin receptor signaling pathwayGO:0007210100.028
regulation of immune responseGO:0050776550.028
protein tetramerizationGO:0051262380.028
cellular response to hormone stimulusGO:00328702470.028
synapse organizationGO:0050808460.028
regulation of synaptic transmission gabaergicGO:0032228170.027
positive regulation of biosynthetic processGO:00098913190.027
development of primary sexual characteristicsGO:00451371070.027
Rat
negative regulation of cell differentiationGO:0045596990.027
response to transition metal nanoparticleGO:19902671220.027
signal releaseGO:00230611450.027
amide transportGO:00428861050.027
purine ribonucleotide catabolic processGO:00091541360.027
positive regulation of cell motilityGO:2000147970.026
response to campGO:0051591910.026
regenerationGO:00310991630.026
associative learningGO:0008306190.026
anion transmembrane transportGO:0098656770.026
hormone secretionGO:00468791150.026
response to hypoxiaGO:00016662310.026
regulation of cytoskeleton organizationGO:0051493490.025
positive regulation of rna biosynthetic processGO:19026801970.025
phasic smooth muscle contractionGO:001482130.025
gliogenesisGO:0042063930.025
positive regulation of apoptotic processGO:00430651540.025
positive regulation of blood circulationGO:1903524650.025
neuron deathGO:00709971270.025
negative regulation of developmental processGO:00510931250.025
regulation of peptide hormone secretionGO:0090276800.025
acute inflammatory responseGO:0002526580.024
regulation of developmental growthGO:0048638450.024
positive regulation of catalytic activityGO:00430851840.024
cellular ketone metabolic processGO:0042180510.024
positive regulation of cytoskeleton organizationGO:0051495260.024
response to biotic stimulusGO:00096072260.024
negative regulation of neurogenesisGO:0050768780.024
ribonucleotide metabolic processGO:00092592310.024
organelle organizationGO:00069962660.023
negative regulation of molecular functionGO:00440921330.023
positive regulation of cellular component organizationGO:00511302000.023
regulation of exocytosisGO:0017157370.023
regulation of insulin secretionGO:0050796650.023
cell projection morphogenesisGO:00488581230.023
cellular response to glucocorticoid stimulusGO:0071385680.023
regulation of heart rateGO:0002027160.023
single organism organelle organizationGO:19025891800.023
carbohydrate derivative catabolic processGO:19011361470.023
regulation of mapk cascadeGO:00434081160.023
membrane organizationGO:0061024940.023
peptide hormone secretionGO:0030072840.023
neuronal action potentialGO:0019228350.022
cyclic nucleotide biosynthetic processGO:0009190630.022
cellular nitrogen compound catabolic processGO:00442701630.022
negative regulation of phosphorus metabolic processGO:0010563800.022
negative regulation of nitrogen compound metabolic processGO:00511721610.022
regulation of long term neuronal synaptic plasticityGO:0048169150.022
positive regulation of exocytosisGO:0045921190.022
urinary bladder smooth muscle contractionGO:001483240.022
ribonucleotide catabolic processGO:00092611360.022
innate immune responseGO:0045087350.022
regulation of smooth muscle cell proliferationGO:0048660750.022
cell projection assemblyGO:0030031210.022
peptide secretionGO:0002790860.022
response to growth factorGO:00708481890.022
sodium ion transportGO:0006814820.022
heterocycle catabolic processGO:00467001670.022
stress activated protein kinase signaling cascadeGO:0031098370.022
catecholamine secretionGO:0050432330.022
cellular response to growth factor stimulusGO:00713631620.022
regulation of neuron deathGO:19012141150.022
regulation of sequence specific dna binding transcription factor activityGO:0051090350.022
cellular response to corticosteroid stimulusGO:0071384690.022
vasoconstrictionGO:0042310540.022
negative regulation of nervous system developmentGO:0051961790.021
regulation of cellular component biogenesisGO:0044087860.021
smooth muscle cell proliferationGO:0048659770.021
regulation of nucleotide metabolic processGO:00061401170.021
response to retinoic acidGO:0032526630.021
regulation of b cell differentiationGO:004557710.021
negative regulation of hormone secretionGO:0046888460.021
multicellular organismal homeostasisGO:0048871490.021
regulation of peptide secretionGO:0002791820.021
organ regenerationGO:00311001010.021
purine nucleotide metabolic processGO:00061632290.021
reproductive system developmentGO:00614581280.021
Rat
regulation of neuron projection developmentGO:00109751610.021
glycosyl compound metabolic processGO:19016571820.021
positive regulation of hormone secretionGO:0046887650.021
positive regulation of amine transportGO:0051954260.021
striated muscle tissue developmentGO:0014706580.021
endomembrane system organizationGO:0010256480.020
carbohydrate derivative biosynthetic processGO:19011371240.020
rho protein signal transductionGO:0007266110.020
response to radiationGO:00093141370.020
regulation of camp metabolic processGO:0030814430.020
response to mineralocorticoidGO:0051385490.020
organic anion transportGO:00157111320.020
cellular modified amino acid metabolic processGO:0006575610.020
mast cell degranulationGO:0043303100.020
negative regulation of calcium ion importGO:009028120.020
acid secretionGO:0046717480.020
nucleotide metabolic processGO:00091172790.020
regulation of protein localizationGO:0032880810.020
protein localization to organelleGO:0033365570.020
sequestering of metal ionGO:005123890.020
taxisGO:0042330670.020
positive regulation of cell differentiationGO:00455972170.020
cell migrationGO:00164771970.020
Rat
positive regulation of peptide hormone secretionGO:0090277500.019
ribonucleoside triphosphate catabolic processGO:00092031220.019
sequestering of calcium ionGO:005120880.019
muscle organ developmentGO:0007517500.019
vasculature developmentGO:0001944700.019
negative regulation of cell projection organizationGO:0031345500.019
olfactory learningGO:000835510.019
skeletal muscle tissue developmentGO:0007519310.019
ensheathment of neuronsGO:0007272400.019
cell activationGO:0001775970.019
salivary gland developmentGO:000743130.019
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.019
small gtpase mediated signal transductionGO:0007264360.019
organonitrogen compound catabolic processGO:19015651790.019
positive regulation of transcription dna templatedGO:00458931970.019
programmed cell deathGO:00125013920.019
development of primary male sexual characteristicsGO:0046546590.019
Rat

Gfra2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.030
disease of anatomical entityDOID:700.030
substance dependenceDOID:997300.027
disease of mental healthDOID:15000.027
substance related disorderDOID:30300.027
brain diseaseDOID:93600.024
central nervous system diseaseDOID:33100.024
epilepsy syndromeDOID:182600.024