IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Rab6b

RAB6B, member RAS oncogene family

RGD: 1309958
Entrez: 363123
Ensembl: ENSRNOG00000009198
UniProtKB: F1LVC3

Process Predictions
Disease Predictions

Rab6b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
neuron development	GO:0048666	286	0.280
neuron projection development	GO:0031175	273	0.257
neuron differentiation	GO:0030182	368	0.171
regulation of cell development	GO:0060284	263	0.130
regulation of neuron differentiation	GO:0045664	208	0.114
cell projection organization	GO:0030030	302	0.099
macromolecule localization	GO:0033036	252	0.091
positive regulation of multicellular organismal process	GO:0051240	387	0.073
regulation of cellular component organization	GO:0051128	368	0.070
cell part morphogenesis	GO:0032990	123	0.069
regulation of cell differentiation	GO:0045595	320	0.068
regulation of neurogenesis	GO:0050767	247	0.064
cellular component movement	GO:0006928	248	0.064
axon development	GO:0061564	96	0.063
monovalent inorganic cation transport	GO:0015672	172	0.063
regulation of cell projection organization	GO:0031344	175	0.062
neuron projection morphogenesis	GO:0048812	122	0.061
protein complex subunit organization	GO:0071822	302	0.060
regulation of nervous system development	GO:0051960	264	0.058
regulation of neuron projection development	GO:0010975	161	0.058
macromolecular complex assembly	GO:0065003	273	0.055
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.053
regulation of multicellular organismal development	GO:2000026	376	0.053
positive regulation of neurogenesis	GO:0050769	165	0.052
anatomical structure morphogenesis	GO:0009653	298	0.052
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.050
protein complex biogenesis	GO:0070271	263	0.049
cellular component morphogenesis	GO:0032989	155	0.049
regulation of signal transduction	GO:0009966	318	0.049
cell projection morphogenesis	GO:0048858	123	0.046
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.046
organic substance catabolic process	GO:1901575	316	0.046
macromolecular complex subunit organization	GO:0043933	339	0.046
protein complex assembly	GO:0006461	263	0.044
single organism catabolic process	GO:0044712	283	0.042
positive regulation of developmental process	GO:0051094	283	0.040
cellular catabolic process	GO:0044248	295	0.039
organic acid metabolic process	GO:0006082	292	0.038
positive regulation of cell differentiation	GO:0045597	217	0.038
cellular component biogenesis	GO:0044085	368	0.038
cellular component assembly	GO:0022607	360	0.037
purine containing compound metabolic process	GO:0072521	253	0.035
synaptic vesicle endocytosis	GO:0048488	4	0.035
purine ribonucleotide metabolic process	GO:0009150	227	0.034
positive regulation of cell development	GO:0010720	176	0.033
ribonucleotide metabolic process	GO:0009259	231	0.033
nucleobase containing small molecule metabolic process	GO:0055086	316	0.033
positive regulation of cellular component organization	GO:0051130	200	0.033
cation transport	GO:0006812	382	0.032
cell morphogenesis	GO:0000902	142	0.032
reproductive process	GO:0022414	372	0.032
protein oligomerization	GO:0051259	191	0.032
ribonucleotide catabolic process	GO:0009261	136	0.031
regulation of molecular function	GO:0065009	398	0.031
positive regulation of neuron projection development	GO:0010976	99	0.031
positive regulation of cell projection organization	GO:0031346	111	0.031
nucleoside phosphate metabolic process	GO:0006753	283	0.031
single organism membrane organization	GO:0044802	74	0.030
multi organism reproductive process	GO:0044703	262	0.030
positive regulation of neuron differentiation	GO:0045666	126	0.030
regulation of membrane potential	GO:0042391	110	0.029
vesicle mediated transport	GO:0016192	181	0.029
nucleotide metabolic process	GO:0009117	279	0.028
regulation of catabolic process	GO:0009894	113	0.027
single organism reproductive process	GO:0044702	297	0.027
cell morphogenesis involved in differentiation	GO:0000904	119	0.027
ras protein signal transduction	GO:0007265	29	0.027
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.027
positive regulation of response to stimulus	GO:0048584	285	0.026
small gtpase mediated signal transduction	GO:0007264	36	0.026
negative regulation of multicellular organismal process	GO:0051241	203	0.026
carbohydrate derivative metabolic process	GO:1901135	346	0.026
protein localization	GO:0008104	191	0.026
limb morphogenesis	GO:0035108	4	0.025
multicellular organismal reproductive process	GO:0048609	233	0.025
membrane organization	GO:0061024	94	0.024
response to wounding	GO:0009611	254	0.024
metal ion transport	GO:0030001	289	0.024
nucleoside triphosphate catabolic process	GO:0009143	123	0.024
intracellular signal transduction	GO:0035556	314	0.024
embryonic pattern specification	GO:0009880	1	0.024
organic cyclic compound catabolic process	GO:1901361	175	0.023
purine ribonucleoside metabolic process	GO:0046128	168	0.023
regulation of growth	GO:0040008	105	0.023
oxoacid metabolic process	GO:0043436	290	0.023
positive regulation of phosphate metabolic process	GO:0045937	262	0.022
programmed cell death	GO:0012501	392	0.022
locomotion	GO:0040011	237	0.022
axonogenesis	GO:0007409	71	0.022
eye morphogenesis	GO:0048592	4	0.022
intracellular transport	GO:0046907	185	0.021
synaptic transmission	GO:0007268	235	0.021
response to nutrient levels	GO:0031667	370	0.021
positive regulation of catalytic activity	GO:0043085	184	0.021
developmental process involved in reproduction	GO:0003006	159	0.021
ribose phosphate metabolic process	GO:0019693	235	0.021
glycosyl compound metabolic process	GO:1901657	182	0.021
regulation of cellular catabolic process	GO:0031329	101	0.020
regulation of anatomical structure size	GO:0090066	135	0.020
purine nucleotide metabolic process	GO:0006163	229	0.020
regulation of axonogenesis	GO:0050770	37	0.020
purine nucleoside metabolic process	GO:0042278	169	0.020
axis specification	GO:0009798	4	0.020
regulation of alternative mrna splicing via spliceosome	GO:0000381	2	0.020
cellular response to endogenous stimulus	GO:0071495	377	0.020
heterocycle catabolic process	GO:0046700	167	0.020
central nervous system development	GO:0007417	311	0.019
cellular protein localization	GO:0034613	122	0.019
negative regulation of cell development	GO:0010721	82	0.019
establishment of protein localization	GO:0045184	141	0.019
nucleoside triphosphate metabolic process	GO:0009141	144	0.019
nucleoside catabolic process	GO:0009164	126	0.019
nucleotide catabolic process	GO:0009166	139	0.019
regulation of cellular amino acid metabolic process	GO:0006521	2	0.019
regulation of secretion by cell	GO:1903530	208	0.019
regulation of cellular ketone metabolic process	GO:0010565	27	0.019
organelle organization	GO:0006996	266	0.019
response to extracellular stimulus	GO:0009991	380	0.018
purine ribonucleotide catabolic process	GO:0009154	136	0.018
amine metabolic process	GO:0009308	38	0.018
organonitrogen compound catabolic process	GO:1901565	179	0.018
protein phosphorylation	GO:0006468	345	0.018
secretion	GO:0046903	307	0.018
embryonic axis specification	GO:0000578	1	0.018
regulation of neuron death	GO:1901214	115	0.018
reproduction	GO:0000003	245	0.018
organophosphate catabolic process	GO:0046434	148	0.018
cellular amine metabolic process	GO:0044106	38	0.018
growth	GO:0040007	165	0.017
rhythmic process	GO:0048511	156	0.017
multicellular organism reproduction	GO:0032504	233	0.017
proteolysis	GO:0006508	175	0.017
cell motility	GO:0048870	202	0.017
localization of cell	GO:0051674	202	0.017
g protein coupled receptor signaling pathway	GO:0007186	242	0.017
catabolic process	GO:0009056	351	0.017
heart morphogenesis	GO:0003007	3	0.017
purine ribonucleoside catabolic process	GO:0046130	124	0.017
cellular response to growth factor stimulus	GO:0071363	162	0.017
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.016
guanosine containing compound metabolic process	GO:1901068	74	0.016
chemical homeostasis	GO:0048878	292	0.016
response to growth factor	GO:0070848	189	0.016
carbohydrate derivative catabolic process	GO:1901136	147	0.016
transmembrane transport	GO:0055085	412	0.016
cellular response to stress	GO:0033554	269	0.016
developmental growth	GO:0048589	100	0.016
regulation of cell morphogenesis	GO:0022604	77	0.016
circadian rhythm	GO:0007623	88	0.015
positive regulation of phosphorylation	GO:0042327	177	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.015
oxidation reduction process	GO:0055114	304	0.015
positive regulation of cellular biosynthetic process	GO:0031328	295	0.015
transmission of nerve impulse	GO:0019226	42	0.015
glycosyl compound catabolic process	GO:1901658	126	0.015
ribonucleoside catabolic process	GO:0042454	126	0.015
sodium ion transport	GO:0006814	82	0.015
guanosine containing compound catabolic process	GO:1901069	71	0.015
sexual reproduction	GO:0019953	148	0.015
single organism cellular localization	GO:1902580	102	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.015
response to estradiol	GO:0032355	164	0.015
protein transport	GO:0015031	132	0.014
negative regulation of metabolic process	GO:0009892	331	0.014
regulation of phosphorylation	GO:0042325	248	0.014
positive regulation of cell communication	GO:0010647	271	0.014
positive regulation of nervous system development	GO:0051962	178	0.014
cellular ketone metabolic process	GO:0042180	51	0.014
secretion by cell	GO:0032940	248	0.014
cell growth	GO:0016049	104	0.014
negative regulation of nervous system development	GO:0051961	79	0.014
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	41	0.014
positive regulation of cellular amine metabolic process	GO:0033240	3	0.014
regulation of gtpase activity	GO:0043087	57	0.014
regulation of proteasomal protein catabolic process	GO:0061136	4	0.014
peptidyl amino acid modification	GO:0018193	126	0.014
regulation of catalytic activity	GO:0050790	304	0.014
regulation of cellular amine metabolic process	GO:0033238	8	0.014
organophosphate metabolic process	GO:0019637	370	0.014
regulation of anatomical structure morphogenesis	GO:0022603	141	0.014
positive regulation of signal transduction	GO:0009967	175	0.014
respiratory gaseous exchange	GO:0007585	4	0.013
positive regulation of phosphorus metabolic process	GO:0010562	262	0.013
anterior posterior pattern specification	GO:0009952	1	0.013
cytoplasmic transport	GO:0016482	115	0.013
cellular amino acid metabolic process	GO:0006520	107	0.013
head development	GO:0060322	247	0.013
regulation of purine nucleotide metabolic process	GO:1900542	115	0.013
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.013
nucleoside metabolic process	GO:0009116	179	0.013
cellular macromolecule localization	GO:0070727	122	0.013
potassium ion transport	GO:0006813	97	0.013
apoptotic process	GO:0006915	381	0.013
regulation of protein modification process	GO:0031399	194	0.013
negative regulation of neurogenesis	GO:0050768	78	0.013
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.013
protein homooligomerization	GO:0051260	91	0.013
gamete generation	GO:0007276	124	0.013
regulation of cell motility	GO:2000145	131	0.013
response to biotic stimulus	GO:0009607	226	0.013
positive regulation of gene expression	GO:0010628	244	0.012
purine nucleoside catabolic process	GO:0006152	124	0.012
regulation of mrna splicing via spliceosome	GO:0048024	3	0.012
rna localization	GO:0006403	4	0.012
circulatory system development	GO:0072359	134	0.012
negative regulation of cell communication	GO:0010648	158	0.012
neurological system process	GO:0050877	219	0.012
nucleoside phosphate catabolic process	GO:1901292	140	0.012
negative regulation of cell differentiation	GO:0045596	99	0.012
response to oxidative stress	GO:0006979	186	0.012
regulation of intracellular signal transduction	GO:1902531	218	0.012
positive regulation of cellular component biogenesis	GO:0044089	55	0.012
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.012
positive regulation of biosynthetic process	GO:0009891	319	0.012
protein autophosphorylation	GO:0046777	66	0.012
regeneration	GO:0031099	163	0.012
regulation of cell migration	GO:0030334	128	0.012
development of primary sexual characteristics	GO:0045137	107	0.011
positive regulation of intracellular signal transduction	GO:1902533	138	0.011
regulation of hydrolase activity	GO:0051336	143	0.011
negative regulation of cellular metabolic process	GO:0031324	281	0.011
single organism organelle organization	GO:1902589	180	0.011
positive regulation of molecular function	GO:0044093	230	0.011
regulation of protein metabolic process	GO:0051246	289	0.011
regulation of cellular protein metabolic process	GO:0032268	267	0.011
cytoskeleton organization	GO:0007010	111	0.011
neuron death	GO:0070997	127	0.011
cell cell signaling involved in cell fate commitment	GO:0045168	2	0.011
single organism intracellular transport	GO:1902582	166	0.011
positive regulation of cell proliferation	GO:0008284	249	0.011
purine containing compound catabolic process	GO:0072523	138	0.011
positive regulation of rna metabolic process	GO:0051254	203	0.011
regulation of transcription dna templated	GO:0006355	374	0.011
cell cycle checkpoint	GO:0000075	2	0.011
receptor mediated endocytosis	GO:0006898	42	0.011
cytoskeleton dependent cytokinesis	GO:0061640	2	0.011
gtp catabolic process	GO:0006184	71	0.011
response to lipopolysaccharide	GO:0032496	191	0.011
positive regulation of cellular catabolic process	GO:0031331	71	0.010
regulation of vesicle mediated transport	GO:0060627	81	0.010
transcription dna templated	GO:0006351	377	0.010
carboxylic acid metabolic process	GO:0019752	289	0.010
regulation of synaptic transmission	GO:0050804	141	0.010
regulation of notch signaling pathway	GO:0008593	3	0.010
intracellular protein transport	GO:0006886	79	0.010
regulation of phosphate metabolic process	GO:0019220	349	0.010
negative regulation of cell death	GO:0060548	229	0.010
purine nucleotide catabolic process	GO:0006195	136	0.010
cellular nitrogen compound catabolic process	GO:0044270	163	0.010
positive regulation of protein phosphorylation	GO:0001934	135	0.010

Rab6b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.024
nervous system disease	DOID:863	0.024
central nervous system disease	DOID:331	0.016
brain disease	DOID:936	0.013

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