Rattus norvegicus

0 known processes

Adam18

ADAM metallopeptidase domain 18

(Aliases: tMDCIII)

Adam18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amino acid transportGO:0006865700.146
cation transmembrane transportGO:00986552630.126
positive regulation of transportGO:00510502450.121
response to corticosteroidGO:00319602350.106
organic anion transportGO:00157111320.106
cation transportGO:00068123820.105
ion transmembrane transportGO:00342203650.099
anion transportGO:00068201780.091
amine transportGO:0015837570.090
transmembrane transportGO:00550854120.087
vesicle mediated transportGO:00161921810.085
organic acid transportGO:00158491160.078
cellular response to oxygen containing compoundGO:19017013860.076
negative regulation of metabolic processGO:00098923310.076
macromolecule localizationGO:00330362520.076
reproductionGO:00000032450.075
regulation of ion transportGO:00432692450.073
response to estrogenGO:00436272320.071
metal ion transportGO:00300012890.070
response to oxidative stressGO:00069791860.069
regulation of secretionGO:00510462240.068
single organism reproductive processGO:00447022970.063
positive regulation of blood circulationGO:1903524650.061
glycosyl compound metabolic processGO:19016571820.060
multicellular organism reproductionGO:00325042330.058
nitrogen compound transportGO:00717052290.057
neurological system processGO:00508772190.056
somatostatin receptor signaling pathwayGO:003816940.055
muscle contractionGO:0006936880.053
cellular catabolic processGO:00442482950.052
response to inorganic substanceGO:00100353770.052
carboxylic acid transportGO:00469421150.051
response to alkaloidGO:00432791320.050
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.049
multi organism reproductive processGO:00447032620.048
endocytosisGO:0006897840.047
organonitrogen compound catabolic processGO:19015651790.045
regulation of molecular functionGO:00650093980.044
multicellular organismal reproductive processGO:00486092330.044
cellular ketone metabolic processGO:0042180510.043
synaptic transmissionGO:00072682350.043
single organism catabolic processGO:00447122830.043
purine nucleotide metabolic processGO:00061632290.042
oxoacid metabolic processGO:00434362900.040
nucleobase containing small molecule metabolic processGO:00550863160.040
purine nucleoside triphosphate metabolic processGO:00091441410.040
positive regulation of molecular functionGO:00440932300.038
carboxylic acid metabolic processGO:00197522890.038
response to ammonium ionGO:0060359710.037
g protein coupled receptor signaling pathwayGO:00071862420.037
response to biotic stimulusGO:00096072260.037
cellular nitrogen compound catabolic processGO:00442701630.037
chemical homeostasisGO:00488782920.036
reproductive processGO:00224143720.036
catecholamine secretionGO:0050432330.035
cellular chemical homeostasisGO:00550822470.035
single organism behaviorGO:00447081300.034
defense responseGO:00069521940.034
negative regulation of transportGO:00510511360.033
response to reactive oxygen speciesGO:00003021200.033
dicarboxylic acid transportGO:0006835340.033
protein transportGO:00150311320.033
purine nucleoside metabolic processGO:00422781690.032
response to toxic substanceGO:00096361330.032
catabolic processGO:00090563510.031
cell cell signalingGO:00072673350.031
nucleoside metabolic processGO:00091161790.030
positive regulation of ion transportGO:0043270940.030
protein homooligomerizationGO:0051260910.030
response to ethanolGO:00454711620.029
inorganic cation transmembrane transportGO:00986622020.029
regulation of cellular localizationGO:00603412630.029
cellular calcium ion homeostasisGO:00068741600.029
regulation of phosphate metabolic processGO:00192203490.029
sensory perception of painGO:0019233730.029
immune responseGO:00069551040.028
sleepGO:0030431300.028
androgen biosynthetic processGO:0006702100.028
regulation of response to stressGO:00801341260.027
positive regulation of synaptic transmissionGO:0050806620.027
negative regulation of cellular biosynthetic processGO:00313271610.027
monoamine transportGO:0015844430.027
negative regulation of nitrogen compound metabolic processGO:00511721610.026
muscle structure developmentGO:0061061870.026
synaptic transmission glycinergicGO:006001220.026
cellular component assemblyGO:00226073600.026
monovalent inorganic cation transportGO:00156721720.026
grooming behaviorGO:000762540.025
negative regulation of gene expressionGO:00106291990.025
aromatic compound catabolic processGO:00194391680.025
secretionGO:00469033070.025
immune system processGO:00023762040.025
multi multicellular organism processGO:00447061380.024
purine containing compound metabolic processGO:00725212530.024
organic substance catabolic processGO:19015753160.024
organelle organizationGO:00069962660.023
response to external biotic stimulusGO:00432072210.023
circulatory system processGO:00030131830.023
vascular process in circulatory systemGO:0003018960.023
organic cyclic compound catabolic processGO:19013611750.022
cellular response to stressGO:00335542690.022
dephosphorylationGO:0016311980.022
response to metal ionGO:00100382530.022
nucleobase containing compound catabolic processGO:00346551520.021
regulation of anatomical structure sizeGO:00900661350.021
central nervous system developmentGO:00074173110.021
amide transportGO:00428861050.021
purine ribonucleoside metabolic processGO:00461281680.021
negative regulation of molecular functionGO:00440921330.021
response to estradiolGO:00323551640.021
transmission of nerve impulseGO:0019226420.021
nucleotide catabolic processGO:00091661390.021
circulatory system developmentGO:00723591340.021
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.021
regulation of growthGO:00400081050.021
negative regulation of cell communicationGO:00106481580.021
muscle system processGO:00030121150.020
cellular component biogenesisGO:00440853680.020
single organism organelle organizationGO:19025891800.020
positive regulation of secretion by cellGO:19035321280.020
negative regulation of membrane potentialGO:004583750.020
regulation of hormone levelsGO:00108171870.020
regulation of transmembrane transportGO:00347621220.019
ribonucleoside catabolic processGO:00424541260.019
ribonucleoside metabolic processGO:00091191740.019
programmed cell deathGO:00125013920.019
organophosphate catabolic processGO:00464341480.019
organophosphate metabolic processGO:00196373700.019
protein complex biogenesisGO:00702712630.019
hormone metabolic processGO:0042445690.018
regulation of muscle system processGO:0090257790.018
regulation of tube sizeGO:0035150890.018
sexual reproductionGO:00199531480.018
monocarboxylic acid transportGO:0015718520.018
purine nucleoside catabolic processGO:00061521240.018
protein localizationGO:00081041910.018
inorganic ion transmembrane transportGO:00986602290.017
positive regulation of transcription factor import into nucleusGO:004299340.017
cellular response to nitrogen compoundGO:19016992100.017
regulation of membrane potentialGO:00423911100.017
purine ribonucleotide metabolic processGO:00091502270.017
purine ribonucleoside triphosphate metabolic processGO:00092051400.017
ribose phosphate metabolic processGO:00196932350.017
brain developmentGO:00074202470.017
blood circulationGO:00080151830.017
cellular homeostasisGO:00197252520.017
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.017
response to peptide hormoneGO:00434342780.017
gamete generationGO:00072761240.017
organic hydroxy compound transportGO:0015850770.017
carbohydrate derivative catabolic processGO:19011361470.017
regulation of blood vessel sizeGO:0050880890.017
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.016
maternal aggressive behaviorGO:000212530.016
heterocycle catabolic processGO:00467001670.016
neurotransmitter transportGO:0006836420.016
regulation of neurotransmitter levelsGO:0001505420.016
regulation of cell proliferationGO:00421273590.016
response to nutrientGO:00075842480.016
striated muscle tissue developmentGO:0014706580.016
purine containing compound catabolic processGO:00725231380.016
single organism intracellular transportGO:19025821660.016
organic acid metabolic processGO:00060822920.016
nucleoside triphosphate catabolic processGO:00091431230.016
response to decreased oxygen levelsGO:00362932370.016
heart processGO:0003015570.015
response to lipopolysaccharideGO:00324961910.015
circadian sleep wake cycleGO:0042745230.015
response to antibioticGO:0046677390.015
potassium ion transportGO:0006813970.015
regulation of establishment of protein localizationGO:0070201690.015
cellular amino acid metabolic processGO:00065201070.015
cognitionGO:0050890920.015
skeletal muscle tissue developmentGO:0007519310.015
negative regulation of biosynthetic processGO:00098901680.015
regulation of protein metabolic processGO:00512462890.015
purine ribonucleoside catabolic processGO:00461301240.015
cellular cation homeostasisGO:00300031800.015
leukocyte mediated immunityGO:0002443280.015
catecholamine transportGO:0051937370.015
regulation of amine transportGO:0051952540.014
nucleotide metabolic processGO:00091172790.014
nucleoside phosphate metabolic processGO:00067532830.014
response to radiationGO:00093141370.014
glycerolipid metabolic processGO:0046486670.014
negative regulation of phosphate metabolic processGO:0045936800.014
ribonucleoside monophosphate metabolic processGO:0009161880.014
negative regulation of macromolecule metabolic processGO:00106052600.014
cellular metal ion homeostasisGO:00068751720.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
camp metabolic processGO:0046058630.014
response to molecule of bacterial originGO:00022371940.014
positive regulation of cell differentiationGO:00455972170.014
glycosyl compound catabolic processGO:19016581260.014
regulation of response to woundingGO:1903034690.014
divalent inorganic cation homeostasisGO:00725071650.014
response to anoxiaGO:003405940.014
signal releaseGO:00230611450.014
regulation of muscle contractionGO:0006937530.014
feeding behaviorGO:0007631530.013
exocytosisGO:0006887600.013
dna metabolic processGO:0006259960.013
response to glucocorticoidGO:00513842230.013
negative regulation of cellular metabolic processGO:00313242810.013
regulation of cellular amino acid metabolic processGO:000652120.013
behavioral response to ethanolGO:004814910.013
negative regulation of cyclic nucleotide metabolic processGO:0030800150.013
neuronal action potentialGO:0019228350.013
immune effector processGO:0002252530.013
actin filament based processGO:0030029860.013
acid secretionGO:0046717480.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
carbohydrate derivative metabolic processGO:19011353460.013
nucleoside triphosphate metabolic processGO:00091411440.013
positive regulation of immunoglobulin productionGO:000263940.013
regulation of metal ion transportGO:00109591180.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
regulation of immune system processGO:00026821230.013
regulation of apoptotic processGO:00429813350.013
thyroid gland developmentGO:003087810.013
positive regulation of protein phosphorylationGO:00019341350.013
positive regulation of multicellular organismal processGO:00512403870.013
rna metabolic processGO:00160704060.013
female pregnancyGO:00075651220.013
regulation of vesicle mediated transportGO:0060627810.013
homeostatic processGO:00425923310.013
regulation of intracellular signal transductionGO:19025312180.012
negative regulation of signal transductionGO:0009968830.012
sensory perceptionGO:00076001010.012
intracellular signal transductionGO:00355563140.012
regulation of cell growthGO:0001558850.012
ribonucleoside triphosphate catabolic processGO:00092031220.012
regulation of transcription dna templatedGO:00063553740.012
mapk cascadeGO:00001651400.012
positive regulation of protein metabolic processGO:00512471780.012
regulation of neuron deathGO:19012141150.012
positive regulation of phosphorus metabolic processGO:00105622620.012
positive regulation of immune responseGO:0050778420.012
apoptotic processGO:00069153810.012
positive regulation of secretionGO:00510471400.012
calcium ion transportGO:00068161310.012
cellular potassium ion transportGO:0071804720.012
nucleoside catabolic processGO:00091641260.012
regulation of exocytosisGO:0017157370.012
cytosolic calcium ion homeostasisGO:00514801400.012
reactive nitrogen species metabolic processGO:200105710.012
neuron projection morphogenesisGO:00488121220.012
negative regulation of apoptotic processGO:00430661810.012
positive regulation of cellular amine metabolic processGO:003324030.012
cation homeostasisGO:00550801950.012
muscle cell differentiationGO:0042692520.012
endocardial cushion developmentGO:000319710.012
liver developmentGO:0001889900.012
synaptic transmission glutamatergicGO:0035249330.011
nucleoside phosphate catabolic processGO:19012921400.011
response to oxygen levelsGO:00704822650.011
anion transmembrane transportGO:0098656770.011
regulation of catabolic processGO:00098941130.011
cellular response to mechanical stimulusGO:0071260480.011
regulation of cell developmentGO:00602842630.011
adrenal gland developmentGO:0030325110.011
cellular response to oxidative stressGO:0034599760.011
proteolysisGO:00065081750.011
response to nutrient levelsGO:00316673700.011
regulation of cellular protein metabolic processGO:00322682670.011
negative regulation of innate immune responseGO:004582440.011
circadian rhythmGO:0007623880.011
regulation of cell differentiationGO:00455953200.011
sodium ion transportGO:0006814820.011
neuromuscular synaptic transmissionGO:000727420.011
negative regulation of secretionGO:0051048820.011
circadian sleep wake cycle processGO:0022410210.011
positive regulation of nitrogen compound metabolic processGO:00511733340.011
neuron developmentGO:00486662860.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
regulation of cellular ketone metabolic processGO:0010565270.011
b cell mediated immunityGO:001972440.011
negative regulation of phosphorus metabolic processGO:0010563800.011
positive regulation of homeostatic processGO:0032846490.010
regulation of blood circulationGO:19035221100.010
antibiotic transportGO:004289120.010
vasoconstrictionGO:0042310540.010
defense response to gram negative bacteriumGO:005082930.010
response to extracellular stimulusGO:00099913800.010
cellular macromolecule localizationGO:00707271220.010
response to purine containing compoundGO:00140741260.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
positive regulation of developmental processGO:00510942830.010

Adam18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
steroid inherited metabolic disorderDOID:170100.013
lipid metabolism disorderDOID:314600.013
inherited metabolic disorderDOID:65500.013
congenital adrenal hyperplasiaDOID:005081100.013
disease of metabolismDOID:001466700.013