Rattus norvegicus

0 known processes

Pnpla2

patatin-like phospholipase domain containing 2

(Aliases: RGD1309044)

Pnpla2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442552080.762
Human Fly
lipid metabolic processGO:00066292830.521
Human Fly
triglyceride metabolic processGO:0006641210.339
Human Fly
lipid biosynthetic processGO:00086101280.319
neutral lipid metabolic processGO:0006638210.222
Human Fly
single organism biosynthetic processGO:00447113420.215
glycerolipid metabolic processGO:0046486670.210
Human Fly
apoptotic processGO:00069153810.208
carboxylic acid metabolic processGO:00197522890.181
organophosphate metabolic processGO:00196373700.161
acylglycerol metabolic processGO:0006639210.151
Human Fly
oxoacid metabolic processGO:00434362900.148
intracellular signal transductionGO:00355563140.116
secretionGO:00469033070.111
amine metabolic processGO:0009308380.107
cellular response to endogenous stimulusGO:00714953770.102
regulation of programmed cell deathGO:00430673410.095
cellular ketone metabolic processGO:0042180510.092
small molecule biosynthetic processGO:00442831240.092
programmed cell deathGO:00125013920.090
response to oxygen levelsGO:00704822650.089
monocarboxylic acid metabolic processGO:00327871520.085
response to oxidative stressGO:00069791860.078
alcohol metabolic processGO:0006066770.077
negative regulation of programmed cell deathGO:00430691830.076
cellular response to lipidGO:00713962010.075
regulation of protein modification processGO:00313991940.072
cellular amine metabolic processGO:0044106380.071
regulation of cellular ketone metabolic processGO:0010565270.069
regulation of apoptotic processGO:00429813350.069
cellular lipid catabolic processGO:0044242370.068
Human Fly
positive regulation of signalingGO:00230562700.064
response to nutrient levelsGO:00316673700.060
cellular response to oxygen containing compoundGO:19017013860.060
macromolecular complex assemblyGO:00650032730.060
protein complex subunit organizationGO:00718223020.060
organic acid metabolic processGO:00060822920.059
nucleobase containing small molecule metabolic processGO:00550863160.058
regulation of lipid metabolic processGO:0019216680.058
Human
secretion by cellGO:00329402480.058
cellular response to hormone stimulusGO:00328702470.058
protein complex assemblyGO:00064612630.056
nitrogen compound transportGO:00717052290.056
cellular catabolic processGO:00442482950.055
Human Fly
regulation of signal transductionGO:00099663180.055
cellular response to stressGO:00335542690.054
positive regulation of multicellular organismal processGO:00512403870.053
positive regulation of cell communicationGO:00106472710.051
macromolecular complex subunit organizationGO:00439333390.049
cellular component assemblyGO:00226073600.048
response to extracellular stimulusGO:00099913800.048
phospholipid metabolic processGO:0006644610.047
carbohydrate derivative metabolic processGO:19011353460.047
regulation of cellular localizationGO:00603412630.047
cellular response to oxidative stressGO:0034599760.046
neutral lipid biosynthetic processGO:004646070.045
negative regulation of metabolic processGO:00098923310.045
signal releaseGO:00230611450.045
organophosphate biosynthetic processGO:00904071430.045
cellular component biogenesisGO:00440853680.044
positive regulation of intracellular signal transductionGO:19025331380.044
organonitrogen compound biosynthetic processGO:19015661670.042
anion transportGO:00068201780.042
protein phosphorylationGO:00064683450.042
regulation of phosphorylationGO:00423252480.042
response to nutrientGO:00075842480.042
negative regulation of apoptotic processGO:00430661810.041
organic acid biosynthetic processGO:0016053830.041
response to inorganic substanceGO:00100353770.041
phosphatidylethanolamine metabolic processGO:004633710.041
organic substance catabolic processGO:19015753160.040
Human Fly
regulation of intracellular signal transductionGO:19025312180.040
peptide secretionGO:0002790860.038
negative regulation of cell deathGO:00605482290.038
regulation of cellular protein metabolic processGO:00322682670.037
organic hydroxy compound metabolic processGO:19016151150.037
carboxylic acid biosynthetic processGO:0046394830.037
regulation of protein phosphorylationGO:00019321830.037
response to decreased oxygen levelsGO:00362932370.037
regulation of molecular functionGO:00650093980.037
protein homooligomerizationGO:0051260910.036
antral ovarian follicle growthGO:000154730.036
peptide hormone secretionGO:0030072840.036
single organism catabolic processGO:00447122830.035
Human Fly
regulation of phosphate metabolic processGO:00192203490.035
cellular homeostasisGO:00197252520.035
cellular amino acid metabolic processGO:00065201070.035
regulation of catalytic activityGO:00507903040.035
acylglycerol biosynthetic processGO:004646370.035
regulation of cellular amino acid metabolic processGO:000652120.035
carnitine metabolic processGO:000943730.034
hormone transportGO:00099141210.034
regulation of phosphorus metabolic processGO:00511743490.034
cellular response to organonitrogen compoundGO:00714171970.033
regulation of secretionGO:00510462240.033
oxidation reduction processGO:00551143040.033
regulation of protein metabolic processGO:00512462890.033
response to external biotic stimulusGO:00432072210.032
protein oligomerizationGO:00512591910.032
macromolecule localizationGO:00330362520.032
Human Fly
negative regulation of biosynthetic processGO:00098901680.032
response to hypoxiaGO:00016662310.032
regulation of cellular amine metabolic processGO:003323880.031
cellular response to nitrogen compoundGO:19016992100.031
negative regulation of macromolecule metabolic processGO:00106052600.030
negative regulation of signalingGO:00230571570.030
regulation of hormone levelsGO:00108171870.030
establishment of protein localizationGO:00451841410.030
phosphatidic acid biosynthetic processGO:000665410.030
positive regulation of response to stimulusGO:00485842850.029
regulation of secretion by cellGO:19035302080.029
organic acid transportGO:00158491160.029
cellular response to lipopolysaccharideGO:0071222550.028
carboxylic acid transportGO:00469421150.028
nucleoside phosphate metabolic processGO:00067532830.028
cell cell signalingGO:00072673350.028
nucleotide metabolic processGO:00091172790.027
cellular response to organic cyclic compoundGO:00714072020.027
positive regulation of transportGO:00510502450.027
response to purine containing compoundGO:00140741260.026
response to reactive oxygen speciesGO:00003021200.026
positive regulation of phosphate metabolic processGO:00459372620.026
phosphatidylcholine biosynthetic processGO:000665650.026
hormone secretionGO:00468791150.026
positive regulation of cellular biosynthetic processGO:00313282950.025
nucleoside catabolic processGO:00091641260.025
homeostatic processGO:00425923310.025
Fly
long chain fatty acid metabolic processGO:0001676320.025
positive regulation of nitrogen compound metabolic processGO:00511733340.025
organic anion transportGO:00157111320.025
peptide transportGO:0015833970.025
positive regulation of signal transductionGO:00099671750.025
regulation of transferase activityGO:00513381230.024
learning or memoryGO:0007611900.024
positive regulation of phosphorus metabolic processGO:00105622620.024
negative regulation of phosphorus metabolic processGO:0010563800.024
regulation of cell proliferationGO:00421273590.024
response to transition metal nanoparticleGO:19902671220.024
lipid catabolic processGO:0016042460.024
Human Fly
insulin secretionGO:0030073690.024
response to peptideGO:19016522920.024
protein complex biogenesisGO:00702712630.023
catabolic processGO:00090563510.023
Human Fly
ribonucleotide metabolic processGO:00092592310.023
neurotransmitter biosynthetic processGO:004213620.023
regulation of response to external stimulusGO:00321011060.023
positive regulation of phosphorylationGO:00423271770.023
regulation of multicellular organismal developmentGO:20000263760.023
positive regulation of nucleobase containing compound metabolic processGO:00459353190.023
fatty acid beta oxidationGO:0006635220.023
ras protein signal transductionGO:0007265290.022
cellular nitrogen compound catabolic processGO:00442701630.022
cation transportGO:00068123820.022
amide transportGO:00428861050.022
negative regulation of cellular metabolic processGO:00313242810.022
positive regulation of cellular protein metabolic processGO:00322701670.022
chemical homeostasisGO:00488782920.022
Fly
positive regulation of cellular amine metabolic processGO:003324030.022
small gtpase mediated signal transductionGO:0007264360.022
positive regulation of defense responseGO:0031349370.021
response to hydrogen peroxideGO:0042542890.021
fatty acid metabolic processGO:0006631990.021
response to ethanolGO:00454711620.021
organelle organizationGO:00069962660.020
nucleic acid templated transcriptionGO:00976593790.020
regulation of transcription dna templatedGO:00063553740.020
positive regulation of molecular functionGO:00440932300.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
behaviorGO:00076102050.020
epithelial cell differentiationGO:0030855710.020
neurological system processGO:00508772190.020
regulation of nervous system developmentGO:00519602640.020
monocarboxylic acid transportGO:0015718520.020
reproductive processGO:00224143720.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.020
positive regulation of lipid catabolic processGO:005099640.020
Human
regulation of cellular component organizationGO:00511283680.020
nicotinamide nucleotide metabolic processGO:0046496280.019
positive regulation of protein metabolic processGO:00512471780.019
response to acid chemicalGO:00011012220.019
positive regulation of secretionGO:00510471400.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
response to biotic stimulusGO:00096072260.019
negative regulation of multicellular organismal processGO:00512412030.019
central nervous system developmentGO:00074173110.019
purine nucleotide metabolic processGO:00061632290.019
fatty acid oxidationGO:0019395290.019
g protein coupled receptor signaling pathwayGO:00071862420.019
reproductionGO:00000032450.019
signal transduction by phosphorylationGO:00230141440.019
regulation of defense responseGO:0031347680.019
carbohydrate derivative biosynthetic processGO:19011371240.019
negative regulation of cellular biosynthetic processGO:00313271610.019
purine ribonucleotide metabolic processGO:00091502270.019
positive regulation of catalytic activityGO:00430851840.019
defense responseGO:00069521940.019
regulation of cellular catabolic processGO:00313291010.019
Human
phospholipid biosynthetic processGO:0008654290.019
tissue developmentGO:00098882520.019
regulation of cell differentiationGO:00455953200.019
cell type specific apoptotic processGO:00972851340.019
response to bacteriumGO:00096172000.018
heterocycle catabolic processGO:00467001670.018
cellular biogenic amine metabolic processGO:0006576300.018
ribose phosphate metabolic processGO:00196932350.018
organophosphate catabolic processGO:00464341480.018
multicellular organism reproductionGO:00325042330.018
ion homeostasisGO:00508012120.018
positive regulation of biosynthetic processGO:00098913190.018
regulation of rna biosynthetic processGO:20011413810.018
anion transmembrane transportGO:0098656770.018
cofactor metabolic processGO:0051186950.018
head developmentGO:00603222470.018
regulation of proteasomal protein catabolic processGO:006113640.018
response to carbohydrateGO:00097431830.018
circulatory system processGO:00030131830.017
rna biosynthetic processGO:00327743800.017
gland developmentGO:00487321550.017
purine containing compound metabolic processGO:00725212530.017
cognitionGO:0050890920.017
negative regulation of cell differentiationGO:0045596990.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
regulation of peptide hormone secretionGO:0090276800.017
multicellular organismal reproductive processGO:00486092330.017
brain developmentGO:00074202470.017
lipid modificationGO:0030258520.017
blood circulationGO:00080151830.017
positive regulation of protein modification processGO:00314011420.017
neuron differentiationGO:00301823680.017
rna metabolic processGO:00160704060.016
multi organism reproductive processGO:00447032620.016
negative regulation of gene expressionGO:00106291990.016
cellular chemical homeostasisGO:00550822470.016
vascular process in circulatory systemGO:0003018960.016
organic cyclic compound catabolic processGO:19013611750.016
positive regulation of catabolic processGO:0009896780.016
Human
positive regulation of rna metabolic processGO:00512542030.016
response to peptide hormoneGO:00434342780.016
negative regulation of cell communicationGO:00106481580.016
positive regulation of humoral immune responseGO:000292220.016
cdp choline pathwayGO:000665730.016
response to osmotic stressGO:0006970420.016
fatty acid transportGO:0015908250.016
positive regulation of protein phosphorylationGO:00019341350.016
neuron deathGO:00709971270.016
transmembrane transportGO:00550854120.016
cation homeostasisGO:00550801950.016
peptidyl amino acid modificationGO:00181931260.016
regulation of nucleic acid templated transcriptionGO:19035063800.015
defense response to other organismGO:0098542170.015
chromosome segregationGO:000705920.015
glycerophospholipid metabolic processGO:0006650470.015
negative regulation of response to stimulusGO:00485851550.015
triglyceride biosynthetic processGO:001943270.015
positive regulation of programmed cell deathGO:00430681570.015
response to estrogenGO:00436272320.015
fatty acid biosynthetic processGO:0006633330.015
regulation of tumor necrosis factor productionGO:0032680130.015
positive regulation of gene expressionGO:00106282440.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
intracellular transportGO:00469071850.015
regulation of neurotransmitter levelsGO:0001505420.015
regulation of mapk cascadeGO:00434081160.015
acetate ester biosynthetic processGO:190062020.015
regulation of blood vessel sizeGO:0050880890.014
cytokine productionGO:0001816610.014
regulation of catabolic processGO:00098941130.014
Human
ion transmembrane transportGO:00342203650.014
response to campGO:0051591910.014
cellular response to growth factor stimulusGO:00713631620.014
positive regulation of cell deathGO:00109421840.014
single organism reproductive processGO:00447022970.014
response to molecule of bacterial originGO:00022371940.014
coenzyme metabolic processGO:0006732860.014
response to growth factorGO:00708481890.014
regulation of hydrolase activityGO:00513361430.014
negative regulation of developmental processGO:00510931250.014
agingGO:00075682410.014
Fly
response to metal ionGO:00100382530.014
anatomical structure morphogenesisGO:00096532980.014
response to alkaloidGO:00432791320.014
response to other organismGO:00517072200.014
cytokine mediated signaling pathwayGO:0019221430.014
lipid localizationGO:0010876620.014
Human Fly
reactive oxygen species metabolic processGO:0072593370.014
protein transportGO:00150311320.013
lipid oxidationGO:0034440300.013
response to lipopolysaccharideGO:00324961910.013
positive regulation of hydrolase activityGO:0051345860.013
protein localizationGO:00081041910.013
amino acid betaine metabolic processGO:000657730.013
regulation of phagocytosis engulfmentGO:006009940.013
axis specificationGO:000979840.013
negative regulation of catalytic activityGO:00430861030.013
negative regulation of phosphate metabolic processGO:0045936800.013
positive regulation of cell differentiationGO:00455972170.013
tube developmentGO:0035295890.013
negative regulation of nervous system developmentGO:0051961790.013
cellular amino acid biosynthetic processGO:0008652320.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
nucleoside metabolic processGO:00091161790.013
pyridine containing compound metabolic processGO:0072524320.013
very long chain fatty acid metabolic processGO:000003830.013
response to toxic substanceGO:00096361330.013
organic hydroxy compound biosynthetic processGO:1901617510.013
purine ribonucleoside catabolic processGO:00461301240.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
regulation of tube sizeGO:0035150890.013
positive regulation of nervous system developmentGO:00519621780.013
regulation of response to stressGO:00801341260.013
positive regulation of apoptotic processGO:00430651540.013
response to temperature stimulusGO:0009266940.013
long chain fatty acid transportGO:0015909140.013
immune system processGO:00023762040.012
response to fatty acidGO:0070542650.012
cellular response to biotic stimulusGO:0071216590.012
regulation of neuron deathGO:19012141150.012
positive regulation of cell proliferationGO:00082842490.012
transcription dna templatedGO:00063513770.012
regulation of neurogenesisGO:00507672470.012
neurotransmitter uptakeGO:000150430.012
ribonucleoside catabolic processGO:00424541260.012
single organism intracellular transportGO:19025821660.012
carbohydrate derivative catabolic processGO:19011361470.012
carboxylic acid catabolic processGO:0046395490.012
nucleotide catabolic processGO:00091661390.012
urogenital system developmentGO:0001655780.012
regulation of rna metabolic processGO:00512523910.012
positive regulation of fatty acid beta oxidationGO:003200040.012
regulation of growthGO:00400081050.012
kidney developmentGO:0001822670.012
steroid metabolic processGO:0008202730.012
regulation of fatty acid oxidationGO:0046320100.012
neuron apoptotic processGO:0051402880.012
sexual reproductionGO:00199531480.012
purine nucleoside metabolic processGO:00422781690.012
neurotransmitter transportGO:0006836420.012
triglyceride catabolic processGO:001943330.012
Human Fly
cellular response to reactive oxygen speciesGO:0034614550.012
cellular response to alcoholGO:0097306870.012
regulation of hormone secretionGO:00468831060.012
cellular response to insulin stimulusGO:0032869810.012
positive regulation of cellular component organizationGO:00511302000.011
ribonucleotide catabolic processGO:00092611360.011
regulation of cell developmentGO:00602842630.011
glycosyl compound metabolic processGO:19016571820.011
regulation of response to woundingGO:1903034690.011
regulation of lipid biosynthetic processGO:0046890380.011
regulation of nucleotide metabolic processGO:00061401170.011
response to mechanical stimulusGO:00096121340.011
carbohydrate metabolic processGO:00059751300.011
acetyl coa metabolic processGO:0006084170.011
regulation of protein kinase activityGO:00458591050.011
positive regulation of kinase activityGO:0033674770.011
single organism behaviorGO:00447081300.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
nucleoside phosphate biosynthetic processGO:19012931020.011
choline transportGO:001587140.011
regulation of establishment of protein localizationGO:0070201690.011
renal system developmentGO:0072001670.011
defense response to gram negative bacteriumGO:005082930.011
meiotic cell cycle processGO:190304630.011
metal ion transportGO:00300012890.011
alcohol biosynthetic processGO:0046165380.011
positive regulation of cell projection organizationGO:00313461110.011
vesicle mediated transportGO:00161921810.011
sterol metabolic processGO:0016125180.011
negative regulation of lipid biosynthetic processGO:005105520.011
positive regulation of cellular catabolic processGO:0031331710.010
Human
response to monosaccharideGO:00342841590.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
cellular response to molecule of bacterial originGO:0071219560.010
positive regulation of transferase activityGO:0051347810.010
ribose phosphate biosynthetic processGO:0046390870.010
cellular response to acid chemicalGO:0071229750.010
positive regulation of rna biosynthetic processGO:19026801970.010
transcription from rna polymerase ii promoterGO:00063662520.010
positive regulation of cytokine productionGO:0001819420.010
negative regulation of rna biosynthetic processGO:19026791180.010
response to insulinGO:00328681330.010
purine containing compound catabolic processGO:00725231380.010
guanosine containing compound metabolic processGO:1901068740.010
pattern recognition receptor signaling pathwayGO:000222190.010
gastrulationGO:000736920.010
response to ammonium ionGO:0060359710.010
response to estradiolGO:00323551640.010
cellular response to abiotic stimulusGO:0071214850.010

Pnpla2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.033
disease of anatomical entityDOID:700.033
musculoskeletal system diseaseDOID:1700.027
muscular diseaseDOID:008000000.025
myopathyDOID:42300.025
muscle tissue diseaseDOID:6600.025
muscular dystrophyDOID:988400.021
central nervous system diseaseDOID:33100.016
disease of metabolismDOID:001466700.012
sensory system diseaseDOID:005015500.010