Rattus norvegicus

0 known processes

Pnpla8

patatin-like phospholipase domain containing 8

(Aliases: RGD1311444)

Pnpla8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hormone secretionGO:00468791150.227
signal releaseGO:00230611450.187
secretion by cellGO:00329402480.160
regulation of secretionGO:00510462240.148
organic substance catabolic processGO:19015753160.111
regulation of hormone secretionGO:00468831060.111
positive regulation of secretionGO:00510471400.107
reproductive processGO:00224143720.101
secretionGO:00469033070.092
positive regulation of transportGO:00510502450.091
regulation of hormone levelsGO:00108171870.087
positive regulation of cell communicationGO:00106472710.085
regulation of protein metabolic processGO:00512462890.084
regulation of cellular localizationGO:00603412630.083
regulation of cell proliferationGO:00421273590.078
hormone transportGO:00099141210.075
cell cell signalingGO:00072673350.073
single organism behaviorGO:00447081300.067
response to inorganic substanceGO:00100353770.062
reproductionGO:00000032450.061
positive regulation of signalingGO:00230562700.060
metal ion transportGO:00300012890.060
single organism catabolic processGO:00447122830.059
nitrogen compound transportGO:00717052290.058
regulation of cellular ketone metabolic processGO:0010565270.057
regulation of signal transductionGO:00099663180.057
regulation of homeostatic processGO:00328441010.057
intracellular signal transductionGO:00355563140.056
single organism reproductive processGO:00447022970.056
homeostatic processGO:00425923310.055
ribose phosphate metabolic processGO:00196932350.054
positive regulation of multicellular organismal processGO:00512403870.053
multicellular organismal reproductive processGO:00486092330.053
regulation of cellular component movementGO:00512701500.053
positive regulation of molecular functionGO:00440932300.051
response to extracellular stimulusGO:00099913800.051
inorganic ion transmembrane transportGO:00986602290.050
regulation of apoptotic processGO:00429813350.050
regulation of smooth muscle cell proliferationGO:0048660750.050
single organism biosynthetic processGO:00447113420.049
response to peptideGO:19016522920.049
regulation of system processGO:00440572080.048
cellular response to oxygen containing compoundGO:19017013860.048
apoptotic processGO:00069153810.047
catabolic processGO:00090563510.046
regulation of molecular functionGO:00650093980.044
response to decreased oxygen levelsGO:00362932370.043
cellular chemical homeostasisGO:00550822470.042
peptide hormone secretionGO:0030072840.042
muscle cell proliferationGO:0033002840.041
cellular response to endogenous stimulusGO:00714953770.041
regulation of programmed cell deathGO:00430673410.040
regulation of membrane potentialGO:00423911100.039
response to peptide hormoneGO:00434342780.039
multicellular organism reproductionGO:00325042330.039
regulation of catalytic activityGO:00507903040.039
ion transmembrane transportGO:00342203650.038
cellular lipid metabolic processGO:00442552080.037
response to estrogenGO:00436272320.037
cellular catabolic processGO:00442482950.036
macromolecular complex subunit organizationGO:00439333390.036
intracellular transportGO:00469071850.036
regulation of phosphorus metabolic processGO:00511743490.036
peptide secretionGO:0002790860.035
regulation of nucleic acid templated transcriptionGO:19035063800.035
positive regulation of hormone secretionGO:0046887650.035
multi organism reproductive processGO:00447032620.035
transmembrane transportGO:00550854120.035
cellular ketone metabolic processGO:0042180510.035
regulation of cell motilityGO:20001451310.035
negative regulation of cell communicationGO:00106481580.034
response to oxidative stressGO:00069791860.034
amide transportGO:00428861050.034
positive regulation of secretion by cellGO:19035321280.033
peptide transportGO:0015833970.033
oxoacid metabolic processGO:00434362900.033
multi multicellular organism processGO:00447061380.033
behaviorGO:00076102050.033
developmental process involved in reproductionGO:00030061590.033
negative regulation of signalingGO:00230571570.032
regulation of synaptic transmissionGO:00508041410.032
regulation of body fluid levelsGO:0050878900.031
chemical homeostasisGO:00488782920.031
regulation of secretion by cellGO:19035302080.030
cation transportGO:00068123820.030
response to bacteriumGO:00096172000.030
regulation of cell migrationGO:00303341280.029
response to lipopolysaccharideGO:00324961910.029
vesicle mediated transportGO:00161921810.029
regulation of cellular protein metabolic processGO:00322682670.029
positive regulation of catalytic activityGO:00430851840.029
single organism intracellular transportGO:19025821660.028
regulation of response to stressGO:00801341260.028
positive regulation of biosynthetic processGO:00098913190.028
cytoplasmic transportGO:00164821150.027
organic hydroxy compound metabolic processGO:19016151150.027
positive regulation of cellular biosynthetic processGO:00313282950.027
positive regulation of phosphate metabolic processGO:00459372620.027
cellular amine metabolic processGO:0044106380.027
response to monosaccharideGO:00342841590.026
response to nutrient levelsGO:00316673700.026
positive regulation of homeostatic processGO:0032846490.026
regulation of peptide transportGO:0090087870.025
negative regulation of metabolic processGO:00098923310.025
cellular response to nitrogen compoundGO:19016992100.025
regulation of hydrolase activityGO:00513361430.025
positive regulation of peptide secretionGO:0002793520.025
carboxylic acid metabolic processGO:00197522890.025
response to cytokineGO:00340972150.025
calcium ion homeostasisGO:00550741620.025
organelle organizationGO:00069962660.025
positive regulation of protein metabolic processGO:00512471780.024
gamete generationGO:00072761240.024
amine metabolic processGO:0009308380.024
purine nucleotide metabolic processGO:00061632290.024
response to carbohydrateGO:00097431830.024
positive regulation of phosphorylationGO:00423271770.024
response to metal ionGO:00100382530.024
regulation of phosphorylationGO:00423252480.024
action potentialGO:0001508540.023
synaptic transmissionGO:00072682350.023
organic acid metabolic processGO:00060822920.023
regulation of insulin secretionGO:0050796650.023
cellular response to corticosteroid stimulusGO:0071384690.023
positive regulation of peptide hormone secretionGO:0090277500.022
carbohydrate derivative metabolic processGO:19011353460.022
cellular component biogenesisGO:00440853680.022
response to ketoneGO:19016541820.022
oxidation reduction processGO:00551143040.022
negative regulation of macromolecule metabolic processGO:00106052600.022
cellular amino acid metabolic processGO:00065201070.022
sexual reproductionGO:00199531480.022
cellular response to cytokine stimulusGO:00713451270.022
positive regulation of nitrogen compound metabolic processGO:00511733340.022
protein phosphorylationGO:00064683450.022
multicellular organism growthGO:003526410.022
protein complex subunit organizationGO:00718223020.022
cellular response to organonitrogen compoundGO:00714171970.022
positive regulation of cell proliferationGO:00082842490.022
organonitrogen compound biosynthetic processGO:19015661670.021
regulation of protein phosphorylationGO:00019321830.021
regulation of catabolic processGO:00098941130.021
response to growth factorGO:00708481890.021
response to hexoseGO:00097461440.021
organonitrogen compound catabolic processGO:19015651790.021
negative regulation of transportGO:00510511360.021
growthGO:00400071650.021
digestive system processGO:0022600240.021
response to insulinGO:00328681330.021
regulation of neuron deathGO:19012141150.020
regulation of metal ion transportGO:00109591180.020
macromolecular complex assemblyGO:00650032730.020
proteolysisGO:00065081750.020
neurological system processGO:00508772190.020
localization of cellGO:00516742020.020
response to glucoseGO:00097491360.020
negative regulation of cell proliferationGO:00082851190.020
negative regulation of cell deathGO:00605482290.020
negative regulation of hormone secretionGO:0046888460.020
carbohydrate homeostasisGO:0033500750.019
cell migrationGO:00164771970.019
tissue developmentGO:00098882520.019
response to other organismGO:00517072200.019
cellular component assemblyGO:00226073600.019
negative regulation of programmed cell deathGO:00430691830.019
purine ribonucleotide metabolic processGO:00091502270.019
neuron deathGO:00709971270.019
programmed cell deathGO:00125013920.019
smooth muscle cell proliferationGO:0048659770.018
cation homeostasisGO:00550801950.018
organophosphate metabolic processGO:00196373700.018
purine containing compound metabolic processGO:00725212530.018
regulation of establishment of protein localizationGO:0070201690.018
divalent metal ion transportGO:00708381320.018
nucleobase containing small molecule metabolic processGO:00550863160.018
nucleoside phosphate metabolic processGO:00067532830.018
cell motilityGO:00488702020.018
blood circulationGO:00080151830.018
regulation of phosphate metabolic processGO:00192203490.018
axis specificationGO:000979840.017
heterocycle catabolic processGO:00467001670.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
sequestering of calcium ionGO:005120880.017
cellular response to hormone stimulusGO:00328702470.017
negative regulation of protein metabolic processGO:00512481140.017
neuron differentiationGO:00301823680.017
regulation of peptide hormone secretionGO:0090276800.017
positive regulation of response to external stimulusGO:0032103510.017
response to alkaloidGO:00432791320.017
rna metabolic processGO:00160704060.017
neural crest cell developmentGO:001403220.017
positive regulation of developmental processGO:00510942830.017
macromolecule localizationGO:00330362520.017
anion transportGO:00068201780.017
regulation of peptide secretionGO:0002791820.017
protein heterooligomerizationGO:0051291890.017
regulation of cellular amino acid metabolic processGO:000652120.016
gastrulationGO:000736920.016
reproductive structure developmentGO:00486081280.016
negative regulation of molecular functionGO:00440921330.016
positive regulation of hydrolase activityGO:0051345860.016
negative regulation of cellular protein metabolic processGO:00322691060.016
gonad developmentGO:00084061040.016
feeding behaviorGO:0007631530.016
organic hydroxy compound biosynthetic processGO:1901617510.016
protein complex biogenesisGO:00702712630.016
regulation of cell differentiationGO:00455953200.016
organ inductionGO:000175910.016
cellular nitrogen compound catabolic processGO:00442701630.016
regulation of muscle contractionGO:0006937530.016
male sex differentiationGO:0046661640.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
sex differentiationGO:00075481130.016
development of primary sexual characteristicsGO:00451371070.016
reproductive system developmentGO:00614581280.016
g protein coupled receptor signaling pathwayGO:00071862420.016
transcription dna templatedGO:00063513770.015
negative regulation of monooxygenase activityGO:003276930.015
cellular homeostasisGO:00197252520.015
muscle structure developmentGO:0061061870.015
positive regulation of nucleobase containing compound metabolic processGO:00459353190.015
regulation of neuron apoptotic processGO:0043523830.015
response to external biotic stimulusGO:00432072210.015
protein autophosphorylationGO:0046777660.015
positive regulation of response to stimulusGO:00485842850.015
response to organophosphorusGO:00466831020.015
regulation of intracellular signal transductionGO:19025312180.015
nucleic acid templated transcriptionGO:00976593790.015
muscle tissue developmentGO:0060537580.015
protein maturationGO:0051604680.015
response to woundingGO:00096112540.015
response to fluid shear stressGO:0034405160.014
inorganic cation transmembrane transportGO:00986622020.014
response to hypoxiaGO:00016662310.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
regulation of protein modification processGO:00313991940.014
male gamete generationGO:0048232990.014
regulation of protein kinase activityGO:00458591050.014
nucleoside metabolic processGO:00091161790.014
regulation of vesicle mediated transportGO:0060627810.014
negative regulation of secretionGO:0051048820.014
small gtpase mediated signal transductionGO:0007264360.014
cellular response to organic cyclic compoundGO:00714072020.014
positive regulation of brown fat cell proliferationGO:007034910.014
negative regulation of secretion by cellGO:1903531720.014
cellular cation homeostasisGO:00300031800.014
regulation of protein transportGO:0051223680.014
response to purine containing compoundGO:00140741260.014
locomotionGO:00400112370.014
calcium ion transportGO:00068161310.014
transcription from rna polymerase ii promoterGO:00063662520.014
cation transmembrane transportGO:00986552630.014
protein localizationGO:00081041910.014
multicellular organismal signalingGO:0035637440.014
divalent inorganic cation transportGO:00725111340.014
multicellular organismal homeostasisGO:0048871490.014
spermatogenesisGO:0007283990.014
actin filament based processGO:0030029860.014
negative regulation of rna splicingGO:003311930.014
regulation of muscle system processGO:0090257790.014
response to molecule of bacterial originGO:00022371940.014
regulation of mrna splicing via spliceosomeGO:004802430.013
metal ion homeostasisGO:00550651860.013
positive regulation of cellular amine metabolic processGO:003324030.013
anterior posterior pattern specificationGO:000995210.013
ribonucleotide metabolic processGO:00092592310.013
regulation of calcium ion transportGO:0051924770.013
cell projection organizationGO:00300303020.013
neuron developmentGO:00486662860.013
negative regulation of neuron deathGO:1901215690.013
carboxylic acid transportGO:00469421150.013
calcium ion transport into cytosolGO:0060402380.013
neuron neuron synaptic transmissionGO:0007270600.013
insulin secretionGO:0030073690.013
regulation of cellular amine metabolic processGO:003323880.013
organic cyclic compound catabolic processGO:19013611750.013
lipid metabolic processGO:00066292830.013
aromatic compound catabolic processGO:00194391680.013
nucleobase containing compound catabolic processGO:00346551520.013
heart morphogenesisGO:000300730.013
response to radiationGO:00093141370.013
response to campGO:0051591910.013
response to estradiolGO:00323551640.013
small molecule biosynthetic processGO:00442831240.013
inflammatory responseGO:00069541500.013
positive regulation of mapk cascadeGO:0043410920.013
fat cell proliferationGO:007034120.013
retinal metabolic processGO:004257430.012
establishment of protein localizationGO:00451841410.012
synaptic vesicle primingGO:001608240.012
ion homeostasisGO:00508012120.012
maintenance of locationGO:0051235170.012
central nervous system developmentGO:00074173110.012
ossificationGO:0001503700.012
terpenoid metabolic processGO:0006721370.012
regulation of anatomical structure sizeGO:00900661350.012
negative regulation of cellular biosynthetic processGO:00313271610.012
negative regulation of cellular metabolic processGO:00313242810.012
alternative mrna splicing via spliceosomeGO:000038040.012
regulation of ion transmembrane transportGO:00347651210.012
negative regulation of catalytic activityGO:00430861030.012
cytoskeleton organizationGO:00070101110.012
positive regulation of cell motilityGO:2000147970.012
divalent inorganic cation homeostasisGO:00725071650.012
response to vitaminGO:00332731310.012
positive regulation of protein modification processGO:00314011420.012
skeletal muscle tissue developmentGO:0007519310.012
protein transportGO:00150311320.012
cellular component movementGO:00069282480.012
cellular protein complex assemblyGO:0043623440.012
regulation of brown fat cell proliferationGO:007034710.012
striated muscle tissue developmentGO:0014706580.012
ras protein signal transductionGO:0007265290.012
regulation of fat cell proliferationGO:007034410.012
endocrine processGO:0050886320.012
transmission of nerve impulseGO:0019226420.011
rna biosynthetic processGO:00327743800.011
regulation of smooth muscle cell migrationGO:0014910360.011
cellular macromolecular complex assemblyGO:0034622580.011
positive regulation of transcription dna templatedGO:00458931970.011
sequestering of metal ionGO:005123890.011
defense responseGO:00069521940.011
response to acid chemicalGO:00011012220.011
reactive oxygen species biosynthetic processGO:190340980.011
cellular response to growth factor stimulusGO:00713631620.011
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.011
reactive nitrogen species metabolic processGO:200105710.011
female pregnancyGO:00075651220.011
developmental inductionGO:003112820.011
positive regulation of phosphorus metabolic processGO:00105622620.011
cellular metal ion homeostasisGO:00068751720.011
regulation of rna biosynthetic processGO:20011413810.011
regulation of response to external stimulusGO:00321011060.011
nucleoside phosphate catabolic processGO:19012921400.011
neuron projection developmentGO:00311752730.011
response to nutrientGO:00075842480.011
response to transforming growth factor betaGO:0071559460.011
regulation of transporter activityGO:0032409500.011
regulation of lipid metabolic processGO:0019216680.010
positive regulation of cellular protein metabolic processGO:00322701670.010
salivary gland developmentGO:000743130.010
response to glucocorticoidGO:00513842230.010
regulation of cellular catabolic processGO:00313291010.010
regulation of nervous system developmentGO:00519602640.010
vascular process in circulatory systemGO:0003018960.010
l glutamate importGO:005193820.010
cellular response to glucose stimulusGO:0071333650.010
agingGO:00075682410.010
regulation of dna metabolic processGO:0051052600.010
calcitriol biosynthetic process from calciolGO:003637820.010
positive regulation of rna biosynthetic processGO:19026801970.010
regulation of transferase activityGO:00513381230.010
regulation of inflammatory responseGO:0050727480.010
cell type specific apoptotic processGO:00972851340.010
positive regulation of cell differentiationGO:00455972170.010
negative regulation of nitrogen compound metabolic processGO:00511721610.010
cellular response to hexose stimulusGO:0071331650.010
regulation of rna metabolic processGO:00512523910.010
cellular response to peptideGO:19016531330.010
nucleotide metabolic processGO:00091172790.010

Pnpla8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.046
disease of anatomical entityDOID:700.046
central nervous system diseaseDOID:33100.017
disease of metabolismDOID:001466700.015
sensory system diseaseDOID:005015500.015
eye and adnexa diseaseDOID:149200.015
inherited metabolic disorderDOID:65500.011