Rattus norvegicus

5 known processes

Serping1

serine (or cysteine) peptidase inhibitor, clade G, member 1

(Aliases: MGC72585)

Serping1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
complement activationGO:0006956110.995
Human
immune effector processGO:0002252530.861
Human
innate immune responseGO:0045087350.482
Human
response to nutrient levelsGO:00316673700.439
response to external biotic stimulusGO:00432072210.342
protein activation cascadeGO:0072376120.334
Human
response to extracellular stimulusGO:00099913800.298
response to other organismGO:00517072200.278
jak stat cascadeGO:0007259260.264
response to molecule of bacterial originGO:00022371940.253
response to biotic stimulusGO:00096072260.233
leukocyte mediated immunityGO:0002443280.194
response to lipopolysaccharideGO:00324961910.187
positive regulation of response to stimulusGO:00485842850.173
Human Rat
cellular response to cytokine stimulusGO:00713451270.159
response to metal ionGO:00100382530.159
Rat
response to nutrientGO:00075842480.158
response to interleukin 1GO:0070555550.156
coagulationGO:0050817280.132
Rat
immune responseGO:00069551040.126
Human
activation of immune responseGO:0002253260.113
Human
cellular response to interleukin 1GO:0071347370.108
regulation of cell projection organizationGO:00313441750.105
Rat
response to glucoseGO:00097491360.104
Rat
response to campGO:0051591910.103
immune system processGO:00023762040.101
Human
response to cytokineGO:00340972150.097
negative regulation of multicellular organismal processGO:00512412030.097
Rat
cell morphogenesis involved in differentiationGO:00009041190.094
protein maturationGO:0051604680.092
Human Mouse
cellular response to lipidGO:00713962010.090
Rat
agingGO:00075682410.087
antigen processing and presentationGO:001988220.084
response to interferon alphaGO:003545510.081
positive regulation of immune system processGO:0002684900.080
Human
rna biosynthetic processGO:00327743800.074
response to interferon betaGO:003545610.073
negative regulation of natural killer cell mediated immunityGO:000271640.068
regulation of viral transcriptionGO:004678220.061
negative regulation of gene expressionGO:00106291990.059
Human Mouse Rat
multi organism reproductive processGO:00447032620.056
cellular response to molecule of bacterial originGO:0071219560.055
peptide cross linkingGO:001814910.055
response to hexoseGO:00097461440.050
Rat
response to bacteriumGO:00096172000.050
viral transcriptionGO:001908320.049
reactive oxygen species metabolic processGO:0072593370.049
embryonic skeletal system developmentGO:004870630.046
regulation of nucleotide biosynthetic processGO:0030808470.046
cellular catabolic processGO:00442482950.046
carbohydrate derivative biosynthetic processGO:19011371240.044
regulation of neurogenesisGO:00507672470.044
Rat
lymphocyte mediated immunityGO:0002449140.043
reproductive processGO:00224143720.042
Rat
regulation of nervous system developmentGO:00519602640.042
Rat
positive regulation of nervous system developmentGO:00519621780.042
Rat
negative regulation of metabolic processGO:00098923310.042
Human Mouse Rat
glial cell differentiationGO:0010001650.042
cellular response to oxygen containing compoundGO:19017013860.041
Rat
viral gene expressionGO:001908020.041
regulation of cell activationGO:0050865500.040
very low density lipoprotein particle remodelingGO:003437210.040
positive regulation of neuron projection developmentGO:0010976990.040
Rat
inflammatory responseGO:00069541500.040
Human Rat
negative regulation of developmental processGO:00510931250.040
respiratory system developmentGO:0060541450.038
regulation of tolerance induction to nonself antigenGO:000265510.037
regulation of viral entry into host cellGO:004659630.037
response to inorganic substanceGO:00100353770.037
Rat
rhythmic processGO:00485111560.037
Rat
positive regulation of gene expressionGO:00106282440.036
cell part morphogenesisGO:00329901230.036
nucleobase containing small molecule metabolic processGO:00550863160.036
morphogenesis of a polarized epitheliumGO:000173810.036
negative regulation of cellular metabolic processGO:00313242810.035
Human Mouse Rat
negative regulation of apoptotic processGO:00430661810.035
organic substance catabolic processGO:19015753160.035
viral genome replicationGO:001907920.035
peptidyl amino acid modificationGO:00181931260.035
organonitrogen compound biosynthetic processGO:19015661670.034
negative regulation of innate immune responseGO:004582440.034
Human
positive regulation of neurogenesisGO:00507691650.033
Rat
defense responseGO:00069521940.033
Human Rat
carbohydrate derivative metabolic processGO:19011353460.033
negative regulation of viral entry into host cellGO:004659730.033
purine containing compound biosynthetic processGO:0072522850.032
protein homotrimerizationGO:0070207150.032
negative regulation of proteolysisGO:0045861410.032
Human Mouse Rat
skeletal system developmentGO:0001501410.032
regulation of innate immune responseGO:0045088150.032
Human
chemical homeostasisGO:00488782920.032
Rat
cellular amine metabolic processGO:0044106380.031
regulation of purine nucleotide metabolic processGO:19005421150.030
head developmentGO:00603222470.030
programmed cell deathGO:00125013920.030
regulation of multicellular organismal developmentGO:20000263760.030
Rat
carbohydrate homeostasisGO:0033500750.029
Rat
regulation of rna metabolic processGO:00512523910.029
liver developmentGO:0001889900.029
cellular response to interleukin 2GO:007135210.029
glycosyl compound metabolic processGO:19016571820.029
regulation of blood circulationGO:19035221100.029
receptor mediated endocytosisGO:0006898420.028
catabolic processGO:00090563510.028
multi multicellular organism processGO:00447061380.028
reproductive system developmentGO:00614581280.028
anterior posterior pattern specificationGO:000995210.028
rna metabolic processGO:00160704060.028
lung developmentGO:0030324430.027
b cell mediated immunityGO:001972440.027
negative regulation of macromolecule metabolic processGO:00106052600.027
Human Mouse Rat
intracellular signal transductionGO:00355563140.027
immunoglobulin mediated immune responseGO:001606440.027
tissue remodelingGO:0048771400.027
response to glucocorticoidGO:00513842230.026
Rat
regulation of cell differentiationGO:00455953200.026
Rat
amine metabolic processGO:0009308380.026
regulation of protein maturationGO:1903317500.026
Human Mouse Rat
negative regulation of viral processGO:004852540.026
positive regulation of cell projection organizationGO:00313461110.026
Rat
cell projection morphogenesisGO:00488581230.025
purine nucleotide biosynthetic processGO:0006164830.025
tyrosine phosphorylation of stat1 proteinGO:004250830.025
negative regulation of programmed cell deathGO:00430691830.025
response to ethanolGO:00454711620.025
homeostatic processGO:00425923310.025
Rat
response to hypoxiaGO:00016662310.025
regulation of protein metabolic processGO:00512462890.025
Human Mouse Rat
response to purine containing compoundGO:00140741260.024
organonitrogen compound catabolic processGO:19015651790.024
cell projection organizationGO:00300303020.024
Rat
kidney developmentGO:0001822670.024
Rat
axon developmentGO:0061564960.024
positive regulation of nucleotide biosynthetic processGO:0030810360.023
regulation of cellular protein metabolic processGO:00322682670.023
Human Mouse Rat
regulation of cellular component organizationGO:00511283680.022
Rat
t cell tolerance inductionGO:000251730.022
regulation of purine nucleotide biosynthetic processGO:1900371460.022
organic acid metabolic processGO:00060822920.022
camp metabolic processGO:0046058630.022
tissue developmentGO:00098882520.022
Rat
cyclic nucleotide metabolic processGO:0009187800.022
response to interferon gammaGO:0034341200.021
oxoacid metabolic processGO:00434362900.021
regulation of peptidase activityGO:0052547550.021
Human Mouse Rat
cyclic nucleotide biosynthetic processGO:0009190630.021
neuron projection morphogenesisGO:00488121220.021
regulation of camp biosynthetic processGO:0030817380.021
chylomicron remodelingGO:003437110.020
multicellular organism reproductionGO:00325042330.020
Rat
transmembrane transportGO:00550854120.020
tolerance induction dependent upon immune responseGO:000246120.020
negative regulation of protein metabolic processGO:00512481140.019
Human Mouse Rat
regulation of proteolysisGO:0030162660.019
Human Mouse Rat
cellular response to extracellular stimulusGO:0031668730.019
adaptive immune responseGO:0002250140.019
macromolecular complex assemblyGO:00650032730.019
response to transition metal nanoparticleGO:19902671220.019
multicellular organismal reproductive processGO:00486092330.019
Rat
antigen processing and presentation of peptide antigenGO:004800220.019
cellular component assemblyGO:00226073600.018
mitotic spindle organizationGO:000705220.018
regulation of signal transductionGO:00099663180.018
negative regulation of cytokine productionGO:0001818160.018
regulation of cyclic nucleotide metabolic processGO:0030799510.018
regulation of developmental growthGO:0048638450.018
signal transduction by phosphorylationGO:00230141440.018
response to organophosphorusGO:00466831020.018
cellular response to metal ionGO:0071248550.017
Rat
negative regulation of neuron deathGO:1901215690.017
Rat
negative regulation of peptidase activityGO:0010466380.017
Human Mouse Rat
proteolysisGO:00065081750.017
Human Mouse Rat
striated muscle tissue developmentGO:0014706580.017
cellular response to external stimulusGO:00714961180.017
cellular response to hexose stimulusGO:0071331650.017
Rat
response to interleukin 2GO:007066910.016
axonogenesisGO:0007409710.016
positive regulation of cellular amine metabolic processGO:003324030.016
cellular response to alcoholGO:0097306870.016
Rat
positive regulation of cyclase activityGO:0031281150.016
lipid localizationGO:0010876620.016
cellular amino acid metabolic processGO:00065201070.016
ion homeostasisGO:00508012120.016
regulation of phosphate metabolic processGO:00192203490.016
negative regulation of molecular functionGO:00440921330.016
Human Mouse Rat
camp biosynthetic processGO:0006171470.016
regulation of immune responseGO:0050776550.016
Human
response to woundingGO:00096112540.016
Human Rat
purine nucleotide metabolic processGO:00061632290.015
response to monosaccharideGO:00342841590.015
Rat
response to decreased oxygen levelsGO:00362932370.015
positive regulation of immune responseGO:0050778420.015
Human
vasculogenesisGO:000157030.015
ras protein signal transductionGO:0007265290.015
regulation of hydrolase activityGO:00513361430.015
Human Mouse Rat
blood coagulation fibrin clot formationGO:007237810.015
regulation of phosphorus metabolic processGO:00511743490.015
regulation of extent of cell growthGO:0061387250.015
positive regulation of cellular component organizationGO:00511302000.014
Rat
respiratory tube developmentGO:0030323430.014
central nervous system developmentGO:00074173110.014
growthGO:00400071650.014
regulation of cell proliferationGO:00421273590.014
negative regulation of endopeptidase activityGO:0010951360.014
Human Mouse Rat
cellular response to endogenous stimulusGO:00714953770.014
Rat
cellular response to stressGO:00335542690.014
circulatory system developmentGO:00723591340.014
ovulation cycleGO:0042698670.014
Rat
regulation of tolerance induction dependent upon immune responseGO:000265210.014
regulation of cell morphogenesisGO:0022604770.014
regulation of catalytic activityGO:00507903040.013
Human Mouse Rat
regulation of cell developmentGO:00602842630.013
Rat
regulation of immune system processGO:00026821230.013
Human
single organism reproductive processGO:00447022970.013
Rat
positive regulation of developmental processGO:00510942830.013
Rat
glucose homeostasisGO:0042593750.013
Rat
endocytosisGO:0006897840.013
regulation of activation of janus kinase activityGO:001053310.013
cellular response to biotic stimulusGO:0071216590.013
positive regulation of neuron differentiationGO:00456661260.013
Rat
negative regulation of catalytic activityGO:00430861030.013
Human Mouse Rat
regulation of axonogenesisGO:0050770370.013
negative regulation of rna metabolic processGO:00512531230.013
response to estradiolGO:00323551640.013
negative regulation of cell deathGO:00605482290.013
Rat
cellular chemical homeostasisGO:00550822470.012
Rat
cellular response to nutrient levelsGO:0031669600.012
response to estrogenGO:00436272320.012
purine nucleobase metabolic processGO:000614440.012
transcription from rna polymerase ii promoterGO:00063662520.012
morphogenesis of an epitheliumGO:0002009200.012
regulation of cellular amino acid metabolic processGO:000652120.012
positive regulation of nucleotide metabolic processGO:0045981910.012
heart developmentGO:0007507720.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
protein complex biogenesisGO:00702712630.012
purine ribonucleotide metabolic processGO:00091502270.012
developmental process involved in reproductionGO:00030061590.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
response to retinoic acidGO:0032526630.011
Rat
regulation of cyclic nucleotide biosynthetic processGO:0030802450.011
regulation of cellular amine metabolic processGO:003323880.011
reproductionGO:00000032450.011
Rat
single organism catabolic processGO:00447122830.011
negative regulation of phosphorus metabolic processGO:0010563800.011
negative regulation of protein maturationGO:1903318470.011
Human Mouse Rat
regulation of locomotionGO:00400121480.011
Rat
positive regulation of cell differentiationGO:00455972170.011
Rat
regulation of viral genome replicationGO:004506920.011
positive regulation of molecular functionGO:00440932300.011
response to virusGO:0009615170.011
regulation of tolerance inductionGO:000264320.011
cardiovascular system developmentGO:00723581340.011
cellular response to growth factor stimulusGO:00713631620.011
brain developmentGO:00074202470.011
cellular response to inorganic substanceGO:0071241650.011
Rat
regulation of endopeptidase activityGO:0052548510.011
Human Mouse Rat
purine ribonucleotide biosynthetic processGO:0009152810.011
hepaticobiliary system developmentGO:0061008900.010
regulation of catabolic processGO:00098941130.010
regulation of neuron differentiationGO:00456642080.010
Rat
negative regulation of viral genome replicationGO:004507110.010
response to foodGO:0032094270.010
positive regulation of phosphorus metabolic processGO:00105622620.010
regulation of rna biosynthetic processGO:20011413810.010
response to corticosteroidGO:00319602350.010
Rat
protein phosphorylationGO:00064683450.010
male mating behaviorGO:006017930.010
positive regulation of tolerance induction dependent upon immune responseGO:000265410.010
protein lipid complex remodelingGO:003436810.010

Serping1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
acquired metabolic diseaseDOID:006015800.025
disease of metabolismDOID:001466700.025
disease of anatomical entityDOID:700.020
Human
vascular diseaseDOID:17800.020
cardiovascular system diseaseDOID:128700.020
nervous system diseaseDOID:86300.015
eye diseaseDOID:561400.014
eye and adnexa diseaseDOID:149200.014
retinal degenerationDOID:846600.014
retinal diseaseDOID:567900.014
macular degenerationDOID:444800.014
sensory system diseaseDOID:005015500.014
age related macular degenerationDOID:1087100.014
degeneration of macula and posterior poleDOID:200700.014
artery diseaseDOID:005082800.013