IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Nudt8

nudix (nucleoside diphosphate linked moiety X)-type motif 8

Ensembl: ENSRNOG00000017955
RGD: 1309040
Entrez: 361692
UniProtKB: D3ZEH6

Process Predictions
Disease Predictions

Nudt8 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular chemical homeostasis	GO:0055082	247	0.124
response to purine containing compound	GO:0014074	126	0.124
organic hydroxy compound metabolic process	GO:1901615	115	0.107
neurological system process involved in regulation of systemic arterial blood pressure	GO:0001976	3	0.097
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.096
lipid biosynthetic process	GO:0008610	128	0.072
chemical homeostasis	GO:0048878	292	0.068
cytosolic calcium ion homeostasis	GO:0051480	140	0.060
lipid metabolic process	GO:0006629	283	0.058
alcohol metabolic process	GO:0006066	77	0.053
positive regulation of epithelial cell proliferation	GO:0050679	32	0.051
homeostatic process	GO:0042592	331	0.049
response to extracellular stimulus	GO:0009991	380	0.049
transcription dna templated	GO:0006351	377	0.048
rna metabolic process	GO:0016070	406	0.046
negative regulation of transport	GO:0051051	136	0.043
regulation of nucleic acid templated transcription	GO:1903506	380	0.043
cellular homeostasis	GO:0019725	252	0.036
positive regulation of biosynthetic process	GO:0009891	319	0.035
secretion	GO:0046903	307	0.034
metal ion homeostasis	GO:0055065	186	0.034
carboxylic acid metabolic process	GO:0019752	289	0.033
cellular response to oxygen containing compound	GO:1901701	386	0.033
regulation of neurogenesis	GO:0050767	247	0.031
regulation of nervous system development	GO:0051960	264	0.030
regulation of rna metabolic process	GO:0051252	391	0.030
regulation of hormone secretion	GO:0046883	106	0.028
single organism biosynthetic process	GO:0044711	342	0.027
regulation of catalytic activity	GO:0050790	304	0.027
androgen biosynthetic process	GO:0006702	10	0.027
amine metabolic process	GO:0009308	38	0.027
divalent inorganic cation homeostasis	GO:0072507	165	0.026
response to growth factor	GO:0070848	189	0.026
response to organophosphorus	GO:0046683	102	0.025
regulation of neuron differentiation	GO:0045664	208	0.025
nucleic acid templated transcription	GO:0097659	379	0.025
cellular response to stress	GO:0033554	269	0.024
rna biosynthetic process	GO:0032774	380	0.024
response to inorganic substance	GO:0010035	377	0.024
cellular amine metabolic process	GO:0044106	38	0.024
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.024
alcohol biosynthetic process	GO:0046165	38	0.023
positive regulation of gene expression	GO:0010628	244	0.023
negative regulation of secretion by cell	GO:1903531	72	0.023
c21 steroid hormone biosynthetic process	GO:0006700	10	0.023
phospholipid metabolic process	GO:0006644	61	0.023
secretion by cell	GO:0032940	248	0.022
hormone biosynthetic process	GO:0042446	25	0.022
steroid metabolic process	GO:0008202	73	0.022
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.022
small molecule biosynthetic process	GO:0044283	124	0.022
cellular response to lipid	GO:0071396	201	0.022
response to peptide hormone	GO:0043434	278	0.021
regulation of multicellular organismal development	GO:2000026	376	0.021
response to estrogen	GO:0043627	232	0.021
erk1 and erk2 cascade	GO:0070371	48	0.021
response to nutrient levels	GO:0031667	370	0.021
positive regulation of cellular biosynthetic process	GO:0031328	295	0.021
regulation of secretion	GO:0051046	224	0.020
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.020
regulation of transcription dna templated	GO:0006355	374	0.020
response to cytokine	GO:0034097	215	0.020
oxoacid metabolic process	GO:0043436	290	0.020
cellular response to hormone stimulus	GO:0032870	247	0.020
negative regulation of secretion	GO:0051048	82	0.020
cellular ion homeostasis	GO:0006873	184	0.020
ovulation cycle process	GO:0022602	50	0.019
regulation of epithelial cell proliferation	GO:0050678	49	0.019
response to reactive oxygen species	GO:0000302	120	0.019
calcium ion homeostasis	GO:0055074	162	0.019
head development	GO:0060322	247	0.019
development of primary sexual characteristics	GO:0045137	107	0.018
ion transmembrane transport	GO:0034220	365	0.018
regulation of cell proliferation	GO:0042127	359	0.018
cellular ketone metabolic process	GO:0042180	51	0.018
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.018
brain renin angiotensin system	GO:0002035	3	0.018
regulation of secretion by cell	GO:1903530	208	0.018
cellular response to organic cyclic compound	GO:0071407	202	0.018
brain development	GO:0007420	247	0.018
cation transport	GO:0006812	382	0.018
regulation of hormone levels	GO:0010817	187	0.018
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.017
response to vitamin	GO:0033273	131	0.017
positive regulation of catalytic activity	GO:0043085	184	0.017
embryonic cranial skeleton morphogenesis	GO:0048701	2	0.017
c21 steroid hormone metabolic process	GO:0008207	14	0.016
protein oligomerization	GO:0051259	191	0.016
parasympathetic nervous system development	GO:0048486	1	0.016
female sex differentiation	GO:0046660	59	0.016
negative regulation of nervous system development	GO:0051961	79	0.016
negative regulation of hormone secretion	GO:0046888	46	0.016
action potential	GO:0001508	54	0.015
cytoplasmic transport	GO:0016482	115	0.015
regulation of neuron projection development	GO:0010975	161	0.015
response to acid chemical	GO:0001101	222	0.015
bone development	GO:0060348	25	0.015
phospholipid biosynthetic process	GO:0008654	29	0.015
positive regulation of multicellular organismal process	GO:0051240	387	0.015
multicellular organismal reproductive process	GO:0048609	233	0.015
regulation of molecular function	GO:0065009	398	0.015
protein complex assembly	GO:0006461	263	0.015
transcription from rna polymerase ii promoter	GO:0006366	252	0.014
response to nutrient	GO:0007584	248	0.014
response to camp	GO:0051591	91	0.014
angiogenesis involved in coronary vascular morphogenesis	GO:0060978	3	0.014
cellular calcium ion homeostasis	GO:0006874	160	0.014
regulation of ion homeostasis	GO:2000021	63	0.014
negative regulation of cell development	GO:0010721	82	0.014
organ induction	GO:0001759	1	0.014
positive regulation of rna metabolic process	GO:0051254	203	0.014
catabolic process	GO:0009056	351	0.013
response to hexose	GO:0009746	144	0.013
positive regulation of developmental process	GO:0051094	283	0.013
response to carbohydrate	GO:0009743	183	0.013
response to heat	GO:0009408	60	0.013
cell projection organization	GO:0030030	302	0.013
negative regulation of gene expression	GO:0010629	199	0.013
negative regulation of metabolic process	GO:0009892	331	0.013
cellular response to oxygen levels	GO:0071453	60	0.013
protein complex subunit organization	GO:0071822	302	0.013
central nervous system development	GO:0007417	311	0.013
negative regulation of macromolecule metabolic process	GO:0010605	260	0.013
acid secretion	GO:0046717	48	0.013
cellular lipid metabolic process	GO:0044255	208	0.013
regulation of programmed cell death	GO:0043067	341	0.013
positive regulation of molecular function	GO:0044093	230	0.012
defense response	GO:0006952	194	0.012
sex differentiation	GO:0007548	113	0.012
response to other organism	GO:0051707	220	0.012
protein complex biogenesis	GO:0070271	263	0.012
steroid biosynthetic process	GO:0006694	48	0.012
gonad development	GO:0008406	104	0.012
reproductive system development	GO:0061458	128	0.012
oxidation reduction process	GO:0055114	304	0.012
regulation of cellular amine metabolic process	GO:0033238	8	0.012
negative regulation of neuron differentiation	GO:0045665	62	0.012
epithelial cell proliferation	GO:0050673	54	0.012
response to oxidative stress	GO:0006979	186	0.012
neuron differentiation	GO:0030182	368	0.012
positive regulation of cell differentiation	GO:0045597	217	0.011
cellular response to endogenous stimulus	GO:0071495	377	0.011
circadian rhythm	GO:0007623	88	0.011
cellular response to growth factor stimulus	GO:0071363	162	0.011
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.011
reproduction	GO:0000003	245	0.011
positive regulation of brown fat cell proliferation	GO:0070349	1	0.011
organophosphate metabolic process	GO:0019637	370	0.011
apoptotic process	GO:0006915	381	0.011
response to hypoxia	GO:0001666	231	0.011
regulation of cellular ketone metabolic process	GO:0010565	27	0.011
single organism reproductive process	GO:0044702	297	0.011
vesicle mediated transport	GO:0016192	181	0.011
response to interleukin 1	GO:0070555	55	0.011
response to transition metal nanoparticle	GO:1990267	122	0.011
organophosphate biosynthetic process	GO:0090407	143	0.011
positive regulation of neuron differentiation	GO:0045666	126	0.011
negative regulation of cell communication	GO:0010648	158	0.011
signal release	GO:0023061	145	0.011
multicellular organism reproduction	GO:0032504	233	0.011
leydig cell differentiation	GO:0033327	8	0.010
cellular hormone metabolic process	GO:0034754	49	0.010
negative regulation of neurogenesis	GO:0050768	78	0.010
multi organism reproductive process	GO:0044703	262	0.010
palate development	GO:0060021	2	0.010
response to peptide	GO:1901652	292	0.010
androgen metabolic process	GO:0008209	14	0.010
glucocorticoid metabolic process	GO:0008211	7	0.010
defense response to gram negative bacterium	GO:0050829	3	0.010

Nudt8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.019
cardiovascular system disease	DOID:1287	0.019
heart disease	DOID:114	0.019
myopathy	DOID:423	0.013
musculoskeletal system disease	DOID:17	0.013
muscular disease	DOID:0080000	0.013
muscle tissue disease	DOID:66	0.013
intrinsic cardiomyopathy	DOID:0060036	0.011
cardiomyopathy	DOID:0050700	0.011
dilated cardiomyopathy	DOID:12930	0.011

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