Rattus norvegicus

0 known processes

Stat4

signal transducer and activator of transcription 4

Stat4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to endogenous stimulusGO:00714953770.468
Rat
response to peptide hormoneGO:00434342780.304
Rat
regulation of signal transductionGO:00099663180.252
response to acid chemicalGO:00011012220.182
negative regulation of cellular metabolic processGO:00313242810.145
Rat
carboxylic acid metabolic processGO:00197522890.138
response to estrogenGO:00436272320.136
Rat
cellular response to oxygen containing compoundGO:19017013860.133
Rat
regulation of cell differentiationGO:00455953200.128
Rat
response to radiationGO:00093141370.124
negative regulation of cellular biosynthetic processGO:00313271610.119
Rat
response to other organismGO:00517072200.119
Rat
regulation of cellular protein metabolic processGO:00322682670.109
regulation of multicellular organismal developmentGO:20000263760.104
Rat
regulation of protein metabolic processGO:00512462890.099
single organism reproductive processGO:00447022970.098
Rat
response to amino acidGO:0043200750.094
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.092
response to lipopolysaccharideGO:00324961910.091
Rat
reproductive processGO:00224143720.091
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.090
Rat
cellular ketone metabolic processGO:0042180510.088
central nervous system developmentGO:00074173110.087
oxoacid metabolic processGO:00434362900.085
negative regulation of macromolecule metabolic processGO:00106052600.084
Rat
programmed cell deathGO:00125013920.083
regulation of cell developmentGO:00602842630.082
Rat
protein phosphorylationGO:00064683450.080
negative regulation of metabolic processGO:00098923310.080
Rat
cellular response to nitrogen compoundGO:19016992100.079
Rat
hematopoietic or lymphoid organ developmentGO:0048534360.079
positive regulation of neurogenesisGO:00507691650.078
positive regulation of response to stimulusGO:00485842850.077
regulation of rna biosynthetic processGO:20011413810.074
Rat
reproductionGO:00000032450.074
Rat
amine metabolic processGO:0009308380.074
regulation of programmed cell deathGO:00430673410.074
organic acid metabolic processGO:00060822920.071
rna metabolic processGO:00160704060.071
Rat
immune system processGO:00023762040.069
response to cytokineGO:00340972150.068
Rat
negative regulation of nucleic acid templated transcriptionGO:19035071170.068
Rat
response to peptideGO:19016522920.066
Rat
regulation of protein phosphorylationGO:00019321830.066
response to nutrientGO:00075842480.065
Rat
regulation of nucleic acid templated transcriptionGO:19035063800.065
Rat
cellular response to external stimulusGO:00714961180.064
regulation of regulatory t cell differentiationGO:004558920.063
cellular response to hormone stimulusGO:00328702470.063
Rat
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.062
Rat
negative regulation of biosynthetic processGO:00098901680.061
Rat
immune system developmentGO:0002520410.060
positive regulation of multicellular organismal processGO:00512403870.059
embryonic skeletal system developmentGO:004870630.058
regulation of protein modification processGO:00313991940.058
leukocyte activationGO:0045321760.058
apoptotic processGO:00069153810.057
cellular amine metabolic processGO:0044106380.054
negative regulation of nucleobase containing compound metabolic processGO:00459341530.054
Rat
regulation of cellular amino acid metabolic processGO:000652120.054
intracellular signal transductionGO:00355563140.053
Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.053
Rat
positive regulation of protein metabolic processGO:00512471780.053
positive regulation of cellular amine metabolic processGO:003324030.053
myeloid cell differentiationGO:0030099220.052
regulation of cellular ketone metabolic processGO:0010565270.052
regulation of immune system processGO:00026821230.052
regulation of neurogenesisGO:00507672470.051
positive regulation of programmed cell deathGO:00430681570.051
positive regulation of cellular protein metabolic processGO:00322701670.051
cellular amino acid metabolic processGO:00065201070.050
positive regulation of cellular biosynthetic processGO:00313282950.050
Rat
cellular response to lipopolysaccharideGO:0071222550.050
regulation of nervous system developmentGO:00519602640.049
g protein coupled receptor signaling pathwayGO:00071862420.049
multicellular organismal reproductive processGO:00486092330.049
Rat
sexual reproductionGO:00199531480.047
positive regulation of developmental processGO:00510942830.047
multi organism reproductive processGO:00447032620.046
cellular response to lipidGO:00713962010.046
response to glucocorticoidGO:00513842230.046
negative regulation of rna metabolic processGO:00512531230.046
Rat
positive regulation of nervous system developmentGO:00519621780.046
positive regulation of cell developmentGO:00107201760.045
response to growth factorGO:00708481890.045
Rat
regulation of transcription dna templatedGO:00063553740.045
Rat
gland developmentGO:00487321550.045
Rat
positive regulation of cellular amino acid metabolic processGO:004576410.044
developmental process involved in reproductionGO:00030061590.044
Rat
regulation of neuron deathGO:19012141150.044
Rat
locomotionGO:00400112370.042
proteolysisGO:00065081750.042
regulation of apoptotic processGO:00429813350.042
regulation of phosphorylationGO:00423252480.042
peptidyl amino acid modificationGO:00181931260.042
positive regulation of phosphate metabolic processGO:00459372620.042
Rat
positive regulation of biosynthetic processGO:00098913190.042
Rat
regulation of rna metabolic processGO:00512523910.041
Rat
regulation of molecular functionGO:00650093980.041
response to molecule of bacterial originGO:00022371940.040
Rat
response to external biotic stimulusGO:00432072210.040
Rat
t cell activationGO:0042110290.039
multicellular organism reproductionGO:00325042330.039
Rat
response to purine containing compoundGO:00140741260.039
Rat
positive regulation of cell differentiationGO:00455972170.039
positive regulation of nitrogen compound metabolic processGO:00511733340.038
Rat
nucleic acid templated transcriptionGO:00976593790.038
Rat
negative regulation of rna biosynthetic processGO:19026791180.038
Rat
t cell receptor signaling pathwayGO:005085210.038
positive regulation of phosphorylationGO:00423271770.038
negative regulation of cell deathGO:00605482290.037
Rat
cell type specific apoptotic processGO:00972851340.037
negative regulation of signalingGO:00230571570.037
immunoglobulin mediated immune responseGO:001606440.036
regulation of cell proliferationGO:00421273590.036
Rat
positive regulation of transcription dna templatedGO:00458931970.036
Rat
positive regulation of protein modification processGO:00314011420.036
regulation of cellular amine metabolic processGO:003323880.036
hemopoiesisGO:0030097340.035
positive regulation of cell proliferationGO:00082842490.034
Rat
peptidyl tyrosine phosphorylationGO:0018108720.034
response to bacteriumGO:00096172000.034
Rat
negative regulation of gene expressionGO:00106291990.034
Rat
cell projection organizationGO:00300303020.034
rna biosynthetic processGO:00327743800.034
Rat
positive regulation of signalingGO:00230562700.034
positive regulation of cell communicationGO:00106472710.034
response to vitaminGO:00332731310.033
positive regulation of cell deathGO:00109421840.033
response to extracellular stimulusGO:00099913800.033
Rat
growthGO:00400071650.033
regulation of transferase activityGO:00513381230.032
b cell differentiationGO:003018320.032
response to inorganic substanceGO:00100353770.032
Rat
neuron apoptotic processGO:0051402880.032
gliogenesisGO:0042063930.031
response to woundingGO:00096112540.031
cellular amino acid catabolic processGO:0009063210.031
cellular response to abiotic stimulusGO:0071214850.031
negative regulation of multicellular organismal processGO:00512412030.030
Rat
response to decreased oxygen levelsGO:00362932370.029
Rat
lymphocyte differentiationGO:0030098100.029
positive regulation of transcription factor import into nucleusGO:004299340.029
cellular response to biotic stimulusGO:0071216590.028
cellular response to alcoholGO:0097306870.028
regulation of cell projection organizationGO:00313441750.028
positive regulation of apoptotic processGO:00430651540.028
leukocyte differentiationGO:0002521300.027
male gonad developmentGO:0008584590.027
response to metal ionGO:00100382530.027
response to reactive oxygen speciesGO:00003021200.027
Rat
cellular response to peptide hormone stimulusGO:00713751200.027
Rat
regulation of catalytic activityGO:00507903040.026
cellular response to growth factor stimulusGO:00713631620.026
Rat
positive regulation of gene expressionGO:00106282440.026
Rat
response to nutrient levelsGO:00316673700.026
Rat
chemical homeostasisGO:00488782920.026
defense responseGO:00069521940.026
Rat
jak stat cascadeGO:0007259260.026
Rat
antigen receptor mediated signaling pathwayGO:005085110.026
cellular component assemblyGO:00226073600.026
dicarboxylic acid metabolic processGO:0043648420.026
regulation of intracellular signal transductionGO:19025312180.025
organophosphate metabolic processGO:00196373700.025
Rat
peptidyl tyrosine modificationGO:0018212720.025
regulation of lymphocyte migrationGO:200040110.025
cellular response to acid chemicalGO:0071229750.025
regulation of phosphorus metabolic processGO:00511743490.025
Rat
cellular response to organic cyclic compoundGO:00714072020.025
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.025
Rat
negative regulation of cellular protein metabolic processGO:00322691060.025
negative regulation of developmental processGO:00510931250.024
Rat
response to ionizing radiationGO:0010212590.024
regulation of protein kinase activityGO:00458591050.024
negative regulation of protein metabolic processGO:00512481140.024
organic substance catabolic processGO:19015753160.024
response to ketoneGO:19016541820.024
response to biotic stimulusGO:00096072260.024
Rat
dna metabolic processGO:0006259960.024
blood circulationGO:00080151830.024
Rat
positive regulation of regulatory t cell differentiationGO:004559120.023
circulatory system processGO:00030131830.023
Rat
positive regulation of kinase activityGO:0033674770.023
neuron projection developmentGO:00311752730.023
response to activityGO:0014823730.023
cell activationGO:0001775970.023
circadian rhythmGO:0007623880.023
positive regulation of molecular functionGO:00440932300.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
Rat
positive regulation of signal transductionGO:00099671750.022
positive regulation of cellular component movementGO:00512721020.022
Rat
positive regulation of neuron differentiationGO:00456661260.022
response to carbohydrateGO:00097431830.022
hormone metabolic processGO:0042445690.022
negative regulation of programmed cell deathGO:00430691830.022
regulation of cellular component organizationGO:00511283680.022
Rat
positive regulation of transferase activityGO:0051347810.022
response to corticosteroidGO:00319602350.022
cellular response to cytokine stimulusGO:00713451270.021
Rat
cellular catabolic processGO:00442482950.021
positive regulation of lipid kinase activityGO:009021820.021
lipid metabolic processGO:00066292830.021
response to insulinGO:00328681330.021
Rat
neuron deathGO:00709971270.021
Rat
hematopoietic progenitor cell differentiationGO:000224420.021
lymphocyte activationGO:0046649430.021
positive regulation of immune system processGO:0002684900.020
necroptotic processGO:007026620.020
organonitrogen compound catabolic processGO:19015651790.020
protein oligomerizationGO:00512591910.020
cellular response to ethanolGO:0071361130.020
response to oxygen levelsGO:00704822650.020
Rat
negative regulation of macromolecule biosynthetic processGO:00105581480.020
Rat
negative regulation of apoptotic processGO:00430661810.020
salivary gland developmentGO:000743130.020
regulation of lipid metabolic processGO:0019216680.020
activation of immune responseGO:0002253260.020
neuron differentiationGO:00301823680.020
positive regulation of transportGO:00510502450.019
respiratory system developmentGO:0060541450.019
response to toxic substanceGO:00096361330.019
transcription dna templatedGO:00063513770.019
Rat
regulation of metanephros developmentGO:007221540.019
Rat
positive regulation of intracellular signal transductionGO:19025331380.019
male sex differentiationGO:0046661640.019
reactive oxygen species biosynthetic processGO:190340980.019
Rat
response to fatty acidGO:0070542650.019
secretion by cellGO:00329402480.019
response to light stimulusGO:0009416520.019
b cell activation involved in immune responseGO:000231210.019
homeostatic processGO:00425923310.018
regulation of cytokine biosynthetic processGO:004203530.018
response to ethanolGO:00454711620.018
Rat
cellular cation homeostasisGO:00300031800.018
regulation of leukocyte activationGO:0002694450.018
lymphoid progenitor cell differentiationGO:000232020.018
tissue developmentGO:00098882520.018
Rat
regulation of lymphocyte chemotaxisGO:190162310.018
immune responseGO:00069551040.017
activation of cysteine type endopeptidase activityGO:009720240.017
carbohydrate metabolic processGO:00059751300.017
hepaticobiliary system developmentGO:0061008900.017
Rat
female pregnancyGO:00075651220.017
cellular response to molecule of bacterial originGO:0071219560.017
programmed necrotic cell deathGO:009730020.017
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.017
c21 steroid hormone biosynthetic processGO:0006700100.017
response to mechanical stimulusGO:00096121340.017
Rat
negative regulation of transcription dna templatedGO:00458921160.017
Rat
tube developmentGO:0035295890.017
Rat
telencephalon developmentGO:0021537620.017
gamete generationGO:00072761240.017
response to oxidative stressGO:00069791860.017
Rat
behaviorGO:00076102050.017
cardiovascular system developmentGO:00723581340.017
ribose phosphate metabolic processGO:00196932350.017
Rat
regulation of locomotionGO:00400121480.016
regulation of kinase activityGO:00435491170.016
dibenzo p dioxin metabolic processGO:0018894100.016
positive regulation of nucleobase containing compound metabolic processGO:00459353190.016
Rat
regulation of reactive oxygen species metabolic processGO:2000377260.016
Rat
negative regulation of cell communicationGO:00106481580.016
cellular macromolecular complex assemblyGO:0034622580.016
cellular response to tumor necrosis factorGO:0071356460.016
heterocycle catabolic processGO:00467001670.016
response to hypoxiaGO:00016662310.016
Rat
single organism carbohydrate metabolic processGO:00447231180.016
positive regulation of cell migrationGO:0030335960.016
cellular response to stressGO:00335542690.016
Rat
positive regulation of protein kinase activityGO:0045860730.015
transmission of nerve impulseGO:0019226420.015
reproductive system developmentGO:00614581280.015
Rat
negative regulation of phosphorus metabolic processGO:0010563800.015
regulation of catabolic processGO:00098941130.015
development of primary male sexual characteristicsGO:0046546590.015
regulatory t cell differentiationGO:004506620.015
mapk cascadeGO:00001651400.015
positive regulation of immune responseGO:0050778420.015
negative regulation of neuron deathGO:1901215690.015
Rat
lung developmentGO:0030324430.015
localization of cellGO:00516742020.015
alpha amino acid catabolic processGO:1901606200.015
salivary gland morphogenesisGO:000743510.015
negative regulation of phosphate metabolic processGO:0045936800.015
negative regulation of molecular functionGO:00440921330.015
neuronal action potentialGO:0019228350.015
regulation of neuron projection developmentGO:00109751610.015
erythrocyte differentiationGO:003021810.015
neurological system processGO:00508772190.014
regulation of neuron differentiationGO:00456642080.014
negative regulation of protein phosphorylationGO:0001933440.014
glial cell differentiationGO:0010001650.014
neuron developmentGO:00486662860.014
regulation of system processGO:00440572080.014
reactive oxygen species metabolic processGO:0072593370.014
Rat
b cell mediated immunityGO:001972440.014
regulation of leukocyte differentiationGO:1902105200.014
positive regulation of locomotionGO:00400171020.014
regulation of isotype switchingGO:004519110.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
Rat
regulation of anatomical structure morphogenesisGO:00226031410.014
Rat
cell cell recognitionGO:000998810.014
embryonic limb morphogenesisGO:003032640.014
reactive nitrogen species metabolic processGO:200105710.014
multi multicellular organism processGO:00447061380.014
cellular response to steroid hormone stimulusGO:0071383930.014
circulatory system developmentGO:00723591340.014
cytokine mediated signaling pathwayGO:0019221430.013
Rat
regulation of cell cycleGO:0051726730.013
cardiac chamber developmentGO:000320510.013
lipid biosynthetic processGO:00086101280.013
regulation of neuron apoptotic processGO:0043523830.013
nucleotide metabolic processGO:00091172790.013
Rat
negative regulation of response to stimulusGO:00485851550.013
embryonic skeletal system morphogenesisGO:004870430.013
negative regulation of phosphorylationGO:0042326570.013
fc receptor mediated stimulatory signaling pathwayGO:000243130.013
single organism cellular localizationGO:19025801020.013
regulation of cell motilityGO:20001451310.013
regulation of cellular localizationGO:00603412630.013
ribonucleoside metabolic processGO:00091191740.013
Rat
innate immune responseGO:0045087350.013
positive regulation of catalytic activityGO:00430851840.013
multicellular organismal signalingGO:0035637440.013
muscle system processGO:00030121150.013
response to estradiolGO:00323551640.013
Rat
protein maturationGO:0051604680.013
cellular chemical homeostasisGO:00550822470.012
ion homeostasisGO:00508012120.012
calcium ion homeostasisGO:00550741620.012
anatomical structure morphogenesisGO:00096532980.012
Rat
xenobiotic metabolic processGO:0006805190.012
response to hyperoxiaGO:0055093450.012
regulation of cell growthGO:0001558850.012
regulation of anatomical structure sizeGO:00900661350.012
negative regulation of signal transductionGO:0009968830.012
alpha beta t cell activationGO:004663130.012
small gtpase mediated signal transductionGO:0007264360.012
positive regulation of defense responseGO:0031349370.012
macromolecular complex subunit organizationGO:00439333390.012
positive regulation of cell projection organizationGO:00313461110.012
single organism organelle organizationGO:19025891800.012
Rat
macromolecular complex assemblyGO:00650032730.012
protein processingGO:0016485680.012
response to tumor cellGO:000234740.012
response to transition metal nanoparticleGO:19902671220.012
response to hydrogen peroxideGO:0042542890.012
Rat
dephosphorylationGO:0016311980.012
synaptic transmissionGO:00072682350.012
metaphase anaphase transition of mitotic cell cycleGO:000709110.012
response to organophosphorusGO:00466831020.012
Rat
smooth muscle cell proliferationGO:0048659770.012
Rat
cellular response to ketoneGO:1901655510.012
organonitrogen compound biosynthetic processGO:19015661670.012
Rat
response to increased oxygen levelsGO:0036296450.012
cell motilityGO:00488702020.012
epithelial cell differentiationGO:0030855710.012
Rat
positive regulation of rna biosynthetic processGO:19026801970.012
Rat
erythrocyte homeostasisGO:003410120.012
cellular response to oxidative stressGO:0034599760.011
Rat
regulation of dna metabolic processGO:0051052600.011
regulation of lymphocyte activationGO:0051249340.011
steroid metabolic processGO:0008202730.011
negative regulation of protein modification processGO:0031400520.011
positive regulation of t cell migrationGO:200040610.011
positive regulation of protein phosphorylationGO:00019341350.011
regulation of hormone levelsGO:00108171870.011
cell cycleGO:00070491010.011
multicellular organism growthGO:003526410.011
cellular component morphogenesisGO:00329891550.011
Rat
regulation of mast cell chemotaxisGO:006075310.011
regulation of body fluid levelsGO:0050878900.011
Rat
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
Rat
regulation of secretionGO:00510462240.011
cellular response to insulin stimulusGO:0032869810.011
Rat
t helper 1 cell extravasationGO:003568710.011
organic cyclic compound catabolic processGO:19013611750.011
negative regulation of catalytic activityGO:00430861030.011
fertilizationGO:000956630.011
transcription from rna polymerase ii promoterGO:00063662520.011
Rat
phthalate metabolic processGO:001896380.011
positive regulation of lipid metabolic processGO:0045834330.011
axis specificationGO:000979840.011
cell growthGO:00160491040.011
catabolic processGO:00090563510.011
positive regulation of cellular component organizationGO:00511302000.011
immune response regulating signaling pathwayGO:0002764190.011
cellular response to transforming growth factor beta stimulusGO:0071560410.011
response to alkaloidGO:00432791320.011
sex differentiationGO:00075481130.011
Rat
t cell differentiationGO:003021790.011
reproductive structure developmentGO:00486081280.011
Rat
positive regulation of necrotic cell deathGO:001094040.011
cellular response to peptideGO:19016531330.011
Rat
dna recombinationGO:000631030.010
regulation of cytokine productionGO:0001817560.010
organic hydroxy compound metabolic processGO:19016151150.010
gastrulationGO:000736920.010
cellular response to vitamin kGO:007130710.010
nucleobase containing small molecule metabolic processGO:00550863160.010
Rat
vesicle mediated transportGO:00161921810.010
rhythmic processGO:00485111560.010
Rat
divalent inorganic cation transportGO:00725111340.010
divalent metal ion transportGO:00708381320.010
carbohydrate derivative catabolic processGO:19011361470.010
chromosome segregationGO:000705920.010
regulation of stem cell differentiationGO:200073620.010
cellular nitrogen compound catabolic processGO:00442701630.010
regulation of mitotic sister chromatid separationGO:001096510.010
cellular response to lipoteichoic acidGO:007122310.010

Stat4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.015
connective tissue diseaseDOID:6500.014
disease of anatomical entityDOID:700.014
musculoskeletal system diseaseDOID:1700.014