Rattus norvegicus

20 known processes

Tie1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

Tie1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vasculogenesisGO:000157030.645
circulatory system developmentGO:00723591340.429
regulation of blood vessel endothelial cell migrationGO:004353540.257
regulation of cellular component organizationGO:00511283680.252
positive regulation of endothelial cell migrationGO:001059540.226
blood vessel morphogenesisGO:0048514580.205
regulation of regulatory t cell differentiationGO:004558920.177
calcium ion homeostasisGO:00550741620.159
regulation of signal transductionGO:00099663180.148
positive regulation of regulatory t cell differentiationGO:004559120.146
cell projection organizationGO:00300303020.136
positive regulation of cell motilityGO:2000147970.135
cellular component movementGO:00069282480.134
regulation of cell motilityGO:20001451310.133
monovalent inorganic cation transportGO:00156721720.114
intracellular signal transductionGO:00355563140.112
Rat
cardiovascular system developmentGO:00723581340.109
divalent inorganic cation homeostasisGO:00725071650.106
positive regulation of phosphate metabolic processGO:00459372620.105
regulation of cellular protein metabolic processGO:00322682670.105
peptidyl amino acid modificationGO:00181931260.100
epithelial cell migrationGO:0010631190.098
divalent inorganic cation transportGO:00725111340.094
negative regulation of cell proliferationGO:00082851190.090
response to organophosphorusGO:00466831020.089
Rat
regulation of cellular amine metabolic processGO:003323880.088
endochondral ossificationGO:000195820.086
Rat
neurological system processGO:00508772190.084
response to fluid shear stressGO:0034405160.082
cell migrationGO:00164771970.081
regulation of locomotionGO:00400121480.081
regulation of cellular component movementGO:00512701500.079
negative regulation of cardiac muscle tissue developmentGO:005502630.078
positive regulation of response to stimulusGO:00485842850.078
organic substance catabolic processGO:19015753160.076
s shaped body morphogenesisGO:007205020.074
response to purine containing compoundGO:00140741260.072
Rat
lipid metabolic processGO:00066292830.071
regulation of membrane potentialGO:00423911100.070
response to oxygen levelsGO:00704822650.068
Rat
transmembrane transportGO:00550854120.067
regulation of phosphate metabolic processGO:00192203490.067
apoptotic processGO:00069153810.066
metal ion transportGO:00300012890.066
organelle organizationGO:00069962660.065
vasculature developmentGO:0001944700.063
organ regenerationGO:00311001010.062
Rat
regulation of cell migrationGO:00303341280.062
blood vessel developmentGO:0001568690.061
negative regulation of developmental processGO:00510931250.061
negative regulation of epithelial cell proliferationGO:0050680160.060
positive regulation of phosphorus metabolic processGO:00105622620.059
anterior posterior pattern specificationGO:000995210.058
response to carbohydrateGO:00097431830.057
negative regulation of multicellular organismal processGO:00512412030.057
cellular component biogenesisGO:00440853680.057
positive regulation of nitrogen compound metabolic processGO:00511733340.057
cation transportGO:00068123820.056
response to decreased oxygen levelsGO:00362932370.056
Rat
chemical homeostasisGO:00488782920.056
heart developmentGO:0007507720.054
cellular component assemblyGO:00226073600.054
cellular protein localizationGO:00346131220.053
regulation of protein modification processGO:00313991940.052
negative regulation of nitrogen compound metabolic processGO:00511721610.052
behaviorGO:00076102050.052
response to monosaccharideGO:00342841590.052
cellular amine metabolic processGO:0044106380.051
positive regulation of biosynthetic processGO:00098913190.051
cellular cation homeostasisGO:00300031800.051
cellular amino acid metabolic processGO:00065201070.051
ameboidal type cell migrationGO:0001667260.050
homeostatic processGO:00425923310.050
embryonic pattern specificationGO:000988010.050
cellular ketone metabolic processGO:0042180510.050
locomotionGO:00400112370.050
localization of cellGO:00516742020.049
ribonucleotide metabolic processGO:00092592310.048
cellular divalent inorganic cation homeostasisGO:00725031620.047
programmed cell deathGO:00125013920.045
protein phosphorylationGO:00064683450.045
cellular macromolecule localizationGO:00707271220.044
cellular response to hormone stimulusGO:00328702470.043
metal ion homeostasisGO:00550651860.043
neuronal action potentialGO:0019228350.043
regulation of cellular ketone metabolic processGO:0010565270.043
regulation of catabolic processGO:00098941130.043
regulation of cellular amino acid metabolic processGO:000652120.043
response to campGO:0051591910.043
Rat
cellular response to oxygen containing compoundGO:19017013860.042
cation transmembrane transportGO:00986552630.042
cellular catabolic processGO:00442482950.041
antigen receptor mediated signaling pathwayGO:005085110.040
muscle tissue developmentGO:0060537580.040
regulation of phosphorus metabolic processGO:00511743490.039
positive regulation of protein modification processGO:00314011420.039
regulation of system processGO:00440572080.039
regulation of molecular functionGO:00650093980.039
regulation of behavioral fear responseGO:200082230.039
positive regulation of signal transductionGO:00099671750.039
myeloid leukocyte differentiationGO:0002573200.039
transcription from rna polymerase ii promoterGO:00063662520.039
negative regulation of cellular biosynthetic processGO:00313271610.037
reproductive processGO:00224143720.037
endothelium developmentGO:0003158120.037
organophosphate metabolic processGO:00196373700.036
positive regulation of cellular amine metabolic processGO:003324030.036
ribonucleoside catabolic processGO:00424541260.035
catabolic processGO:00090563510.035
pro t cell differentiationGO:000257210.034
protein oligomerizationGO:00512591910.034
positive regulation of cell migrationGO:0030335960.034
positive regulation of multicellular organismal processGO:00512403870.034
Rat
protein autophosphorylationGO:0046777660.034
multi multicellular organism processGO:00447061380.034
nucleotide metabolic processGO:00091172790.033
replacement ossificationGO:003607520.033
Rat
macromolecular complex assemblyGO:00650032730.033
female pregnancyGO:00075651220.032
divalent metal ion transportGO:00708381320.032
negative regulation of organ growthGO:004662130.032
purine containing compound metabolic processGO:00725212530.032
regulation of organelle organizationGO:0033043800.032
nucleobase containing small molecule metabolic processGO:00550863160.032
small gtpase mediated signal transductionGO:0007264360.032
metanephric mesenchymal cell migrationGO:003578920.032
positive regulation of epithelial cell migrationGO:0010634130.032
positive regulation of cellular component movementGO:00512721020.031
negative regulation of release of sequestered calcium ion into cytosolGO:005128040.031
cellular homeostasisGO:00197252520.031
positive regulation of cellular amino acid metabolic processGO:004576410.031
blood circulationGO:00080151830.031
nucleoside phosphate metabolic processGO:00067532830.031
negative regulation of cellular component organizationGO:0051129830.030
muscle structure developmentGO:0061061870.030
regulation of metal ion transportGO:00109591180.030
axis specificationGO:000979840.030
regulation of tight junction assemblyGO:200081020.030
cell motilityGO:00488702020.030
epithelial cell proliferationGO:0050673540.030
regulation of angiogenesisGO:0045765390.030
Rat
single organism reproductive processGO:00447022970.029
regulation of cell proliferationGO:00421273590.029
single organism intracellular transportGO:19025821660.029
maintenance of locationGO:0051235170.029
intracellular transportGO:00469071850.029
sensory perceptionGO:00076001010.028
nucleic acid templated transcriptionGO:00976593790.028
regulation of protein metabolic processGO:00512462890.028
multicellular organism growthGO:003526410.028
regulation of ion transportGO:00432692450.028
carbohydrate derivative metabolic processGO:19011353460.028
ribonucleoside metabolic processGO:00091191740.028
head developmentGO:00603222470.028
response to cytokineGO:00340972150.028
immune system processGO:00023762040.027
regulation of epithelial cell migrationGO:0010632170.027
anatomical structure morphogenesisGO:00096532980.027
epithelium migrationGO:0090132190.027
nucleoside triphosphate metabolic processGO:00091411440.027
organophosphate catabolic processGO:00464341480.027
regenerationGO:00310991630.026
Rat
cytoskeleton organizationGO:00070101110.026
regulation of vasculature developmentGO:1901342440.026
Rat
metanephric comma shaped body morphogenesisGO:007227820.026
organonitrogen compound catabolic processGO:19015651790.025
negative regulation of protein metabolic processGO:00512481140.025
calcium ion transportGO:00068161310.025
artery developmentGO:006084030.025
nucleoside metabolic processGO:00091161790.025
positive regulation of defense responseGO:0031349370.025
aromatic compound catabolic processGO:00194391680.024
cell junction organizationGO:0034330210.024
common partner smad protein phosphorylationGO:000718210.024
endocytosisGO:0006897840.024
regulation of stem cell differentiationGO:200073620.024
regulation of intracellular signal transductionGO:19025312180.024
nucleobase containing compound catabolic processGO:00346551520.023
positive regulation of cytosolic calcium ion concentrationGO:00072041220.023
regulatory t cell differentiationGO:004506620.023
purine ribonucleoside triphosphate metabolic processGO:00092051400.023
response to woundingGO:00096112540.023
innate immune responseGO:0045087350.023
carboxylic acid metabolic processGO:00197522890.023
tube formationGO:003514830.023
brain developmentGO:00074202470.023
ion transmembrane transportGO:00342203650.023
regulation of potassium ion transportGO:0043266290.022
ras protein signal transductionGO:0007265290.022
nucleoside triphosphate catabolic processGO:00091431230.022
neuron differentiationGO:00301823680.022
negative regulation of heart growthGO:006111730.022
striated muscle tissue developmentGO:0014706580.022
response to growth factorGO:00708481890.022
protein localizationGO:00081041910.022
myeloid cell differentiationGO:0030099220.022
regulation of nervous system developmentGO:00519602640.022
cellular chemical homeostasisGO:00550822470.022
cell cell junction organizationGO:0045216200.022
response to ketoneGO:19016541820.021
multicellular organismal signalingGO:0035637440.021
positive regulation of ion transportGO:0043270940.021
multi organism reproductive processGO:00447032620.021
hematopoietic progenitor cell differentiationGO:000224420.021
single organism organelle organizationGO:19025891800.021
cellular ion homeostasisGO:00068731840.021
metanephric s shaped body morphogenesisGO:007228420.021
vesicle mediated transportGO:00161921810.021
regulation of epithelial cell proliferationGO:0050678490.021
regulation of transmembrane transportGO:00347621220.021
muscle cell proliferationGO:0033002840.021
oxoacid metabolic processGO:00434362900.021
purine nucleoside triphosphate catabolic processGO:00091461220.021
growthGO:00400071650.021
rna metabolic processGO:00160704060.021
synaptic vesicle exocytosisGO:0016079150.021
cellular metal ion homeostasisGO:00068751720.021
regulation of cell differentiationGO:00455953200.020
hematopoietic or lymphoid organ developmentGO:0048534360.020
actin filament based processGO:0030029860.020
protein complex biogenesisGO:00702712630.020
purine containing compound catabolic processGO:00725231380.020
transcription dna templatedGO:00063513770.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
positive regulation of signalingGO:00230562700.020
purine nucleoside metabolic processGO:00422781690.020
neuron projection developmentGO:00311752730.020
negative regulation of transportGO:00510511360.020
positive regulation of cellular component organizationGO:00511302000.020
protein complex assemblyGO:00064612630.020
regulation of multicellular organismal developmentGO:20000263760.020
Rat
macromolecular complex subunit organizationGO:00439333390.019
cell adhesionGO:00071551100.019
regulation of ras gtpase activityGO:0032318320.019
regulation of rho gtpase activityGO:0032319170.019
ribonucleoside triphosphate metabolic processGO:00091991410.019
regulation of neuron differentiationGO:00456642080.019
defecationGO:003042110.019
cation homeostasisGO:00550801950.019
positive regulation of protein phosphorylationGO:00019341350.019
negative regulation of biosynthetic processGO:00098901680.019
immune system developmentGO:0002520410.019
negative regulation of cellular metabolic processGO:00313242810.019
muscle organ developmentGO:0007517500.019
positive regulation of epidermis developmentGO:004568410.019
cellular response to endogenous stimulusGO:00714953770.019
membrane organizationGO:0061024940.019
nucleotide catabolic processGO:00091661390.019
ion homeostasisGO:00508012120.019
embryonic axis specificationGO:000057810.019
cytoplasmic transportGO:00164821150.018
regulation of anatomical structure sizeGO:00900661350.018
organic anion transportGO:00157111320.018
regulation of nucleic acid templated transcriptionGO:19035063800.018
glycosyl compound metabolic processGO:19016571820.018
renal system processGO:0003014400.018
rho protein signal transductionGO:0007266110.018
response to peptideGO:19016522920.018
Rat
regulation of anatomical structure morphogenesisGO:00226031410.018
Rat
negative regulation of cardiac muscle cell proliferationGO:006004420.018
cgmp biosynthetic processGO:0006182150.018
macromolecule localizationGO:00330362520.018
response to peptide hormoneGO:00434342780.018
Rat
positive regulation of locomotionGO:00400171020.018
positive regulation of tor signalingGO:003200820.018
cell substrate adhesionGO:0031589290.018
positive regulation of transportGO:00510502450.018
negative regulation of transcription regulatory region dna bindingGO:200067820.018
cellular calcium ion homeostasisGO:00068741600.018
anatomical structure formation involved in morphogenesisGO:0048646830.017
Rat
peptidyl tyrosine phosphorylationGO:0018108720.017
dna metabolic processGO:0006259960.017
regulation of skeletal muscle tissue regenerationGO:004341620.017
epithelium developmentGO:0060429960.017
regulation of transcription regulatory region dna bindingGO:200067740.017
regulation of phosphorylationGO:00423252480.017
regulation of small gtpase mediated signal transductionGO:0051056480.017
regulation of intracellular transportGO:0032386650.017
multicellular organism reproductionGO:00325042330.017
cell migration involved in kidney developmentGO:003578720.017
regulation of synaptic transmissionGO:00508041410.017
tissue regenerationGO:0042246360.017
regulation of neurogenesisGO:00507672470.017
organic cyclic compound catabolic processGO:19013611750.016
negative regulation of cardiac muscle tissue growthGO:005502230.016
multicellular organismal response to stressGO:0033555250.016
regulation of cellular localizationGO:00603412630.016
regulation of immune responseGO:0050776550.016
positive regulation of molecular functionGO:00440932300.016
regulation of cell projection organizationGO:00313441750.016
smooth muscle cell proliferationGO:0048659770.016
sequestering of metal ionGO:005123890.016
positive regulation of protein metabolic processGO:00512471780.016
cellular response to corticosteroid stimulusGO:0071384690.016
regulation of phosphatidylinositol 3 kinase activityGO:004355170.016
response to glucoseGO:00097491360.016
positive regulation of cell differentiationGO:00455972170.016
regulation of apoptotic processGO:00429813350.016
regulation of homeostatic processGO:00328441010.016
negative regulation of gene expressionGO:00106291990.016
response to hypoxiaGO:00016662310.016
Rat
single organism membrane organizationGO:0044802740.016
peptidyl tyrosine modificationGO:0018212720.016
negative regulation of calcium ion transport into cytosolGO:001052340.016
regulation of secretionGO:00510462240.016
response to radiationGO:00093141370.016
comma shaped body morphogenesisGO:007204920.016
negative regulation of response to stimulusGO:00485851550.016
angiogenesisGO:0001525530.015
Rat
glial cell differentiationGO:0010001650.015
response to inorganic substanceGO:00100353770.015
positive regulation of immune system processGO:0002684900.015
cd4 positive alpha beta t cell activationGO:003571010.015
single organism behaviorGO:00447081300.015
negative regulation of macromolecule metabolic processGO:00106052600.015
organ growthGO:0035265240.015
transmission of nerve impulseGO:0019226420.015
negative regulation of innate immune responseGO:004582440.015
potassium ion transportGO:0006813970.015
regulation of blood circulationGO:19035221100.015
positive regulation of cellular biosynthetic processGO:00313282950.015
ensheathment of neuronsGO:0007272400.015
regulation of cellular component biogenesisGO:0044087860.015
guanosine containing compound catabolic processGO:1901069710.015
amine metabolic processGO:0009308380.015
circulatory system processGO:00030131830.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
regulation of gtpase activityGO:0043087570.014
negative regulation of apoptotic processGO:00430661810.014
enzyme linked receptor protein signaling pathwayGO:00071671160.014
glucose homeostasisGO:0042593750.014
regulation of ion transmembrane transportGO:00347651210.014
response to mechanical stimulusGO:00096121340.014
positive regulation of transcription dna templatedGO:00458931970.014
negative regulation of nervous system developmentGO:0051961790.014
purine ribonucleotide metabolic processGO:00091502270.014
regulation of kinase activityGO:00435491170.014
ribose phosphate metabolic processGO:00196932350.014
purine nucleotide catabolic processGO:00061951360.014
response to acid chemicalGO:00011012220.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
glycosyl compound catabolic processGO:19016581260.014
regulation of protein phosphorylationGO:00019321830.014
skeletal system developmentGO:0001501410.014
Rat
action potentialGO:0001508540.014
platelet derived growth factor receptor alpha signaling pathwayGO:003579010.014
regulation of catalytic activityGO:00507903040.014
insulin like growth factor receptor signaling pathwayGO:004800930.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
positive regulation of catalytic activityGO:00430851840.014
biological adhesionGO:00226101100.014
positive regulation of fear responseGO:190336730.014
response to corticosteroidGO:00319602350.014
nucleoside phosphate catabolic processGO:19012921400.014
cellular response to organic cyclic compoundGO:00714072020.014
carbohydrate derivative biosynthetic processGO:19011371240.014
embryonic hindlimb morphogenesisGO:003511620.014
cardiac muscle tissue growthGO:0055017200.014
positive regulation of cell communicationGO:00106472710.014
positive regulation of cell communication by chemical couplingGO:001065220.014
cytosolic calcium ion homeostasisGO:00514801400.014
metanephric glomerulus morphogenesisGO:007227510.014
sexual reproductionGO:00199531480.013
synaptic transmissionGO:00072682350.013
regulation of growthGO:00400081050.013
purine nucleotide metabolic processGO:00061632290.013
positive regulation of membrane potentialGO:0045838160.013
nucleoside catabolic processGO:00091641260.013
endochondral bone morphogenesisGO:006035070.013
Rat
angioblast cell migrationGO:003547610.013
positive regulation of rna biosynthetic processGO:19026801970.013
regulation of rna metabolic processGO:00512523910.013
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.013
developmental process involved in reproductionGO:00030061590.013
cell growthGO:00160491040.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.013
positive regulation of lipid kinase activityGO:009021820.013
receptor metabolic processGO:0043112180.013
reactive nitrogen species metabolic processGO:200105710.013
gtp catabolic processGO:0006184710.013
regulation of long term synaptic potentiationGO:190027150.013
regulation of secretion by cellGO:19035302080.013
epithelial cell differentiationGO:0030855710.013
gamete generationGO:00072761240.013
b cell differentiationGO:003018320.013
calcium ion transport into cytosolGO:0060402380.013
myelinationGO:0042552390.013
positive regulation of cellular component biogenesisGO:0044089550.013
anion transportGO:00068201780.013
response to extracellular stimulusGO:00099913800.013
positive regulation of catabolic processGO:0009896780.012
regulation of dna metabolic processGO:0051052600.012
carbohydrate derivative catabolic processGO:19011361470.012
response to hexoseGO:00097461440.012
negative regulation of neuron projection developmentGO:0010977460.012
sterol homeostasisGO:005509230.012
cellular response to glucocorticoid stimulusGO:0071385680.012
cardiac muscle cell proliferationGO:006003860.012
positive regulation of nucleotide metabolic processGO:0045981910.012
negative regulation of osteoblast differentiationGO:004566820.012
negative regulation of cell differentiationGO:0045596990.012
cellular response to growth factor stimulusGO:00713631620.012
negative regulation of immune system processGO:0002683390.012
cellular component morphogenesisGO:00329891550.012
digestive system developmentGO:0055123410.012
multicellular organismal reproductive processGO:00486092330.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
alpha beta t cell differentiationGO:004663220.012
ribonucleotide catabolic processGO:00092611360.012
negative regulation of protein import into nucleus translocationGO:003315910.012
response to estrogenGO:00436272320.012
Rat
defense response to gram negative bacteriumGO:005082930.011
rna biosynthetic processGO:00327743800.011
regulation of endothelial cell differentiationGO:004560140.011
second messenger mediated signalingGO:0019932510.011
negative regulation of endothelial cell proliferationGO:000193750.011
single organism catabolic processGO:00447122830.011
regulation of cardiac muscle tissue developmentGO:0055024120.011
positive regulation of neurogenesisGO:00507691650.011
regulation of leukocyte differentiationGO:1902105200.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
positive regulation of behavioral fear responseGO:200098730.011
regulation of transferase activityGO:00513381230.011
forebrain developmentGO:0030900980.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
chordate embryonic developmentGO:0043009180.011
regulation of actin filament based processGO:0032970420.011
positive regulation of phosphorylationGO:00423271770.011
protein complex subunit organizationGO:00718223020.011
cell communication by chemical couplingGO:001064320.011
skeletal muscle tissue developmentGO:0007519310.011
alcohol metabolic processGO:0006066770.011
t cell differentiationGO:003021790.011
organic acid metabolic processGO:00060822920.011
positive regulation of intracellular transportGO:0032388390.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
reactive oxygen species biosynthetic processGO:190340980.011
pinocytosisGO:000690710.011
regulation of cytoskeleton organizationGO:0051493490.011
regulation of carbohydrate metabolic processGO:0006109410.011
negative regulation of muscle organ developmentGO:004863580.010
positive regulation of cellular protein metabolic processGO:00322701670.010
skeletal muscle organ developmentGO:0060538330.010
regulation of transcription dna templatedGO:00063553740.010
positive regulation of macromolecule biosynthetic processGO:00105572470.010
gastrulationGO:000736920.010
cellular response to carbohydrate stimulusGO:0071322720.010
regulation of alpha beta t cell activationGO:004663420.010
regulation of neuron projection developmentGO:00109751610.010
gland developmentGO:00487321550.010
transforming growth factor beta receptor signaling pathwayGO:0007179180.010
regulation of purine nucleotide metabolic processGO:19005421150.010
cell junction assemblyGO:0034329180.010
negative regulation of molecular functionGO:00440921330.010
developmental growthGO:00485891000.010
wound healingGO:00420601220.010
myeloid progenitor cell differentiationGO:000231810.010
negative regulation of protein phosphorylationGO:0001933440.010

Tie1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.014
nervous system diseaseDOID:86300.014
disease of anatomical entityDOID:700.014
cardiovascular system diseaseDOID:128700.013
vascular diseaseDOID:17800.013