Rattus norvegicus

0 known processes

Gdf15

growth differentiation factor 15

Gdf15 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of multicellular organismal processGO:00512403870.205
response to nutrientGO:00075842480.170
regulation of nucleic acid templated transcriptionGO:19035063800.147
lipid metabolic processGO:00066292830.134
response to glucocorticoidGO:00513842230.130
regulation of molecular functionGO:00650093980.127
response to biotic stimulusGO:00096072260.127
reproductive processGO:00224143720.106
cellular response to hormone stimulusGO:00328702470.106
regulation of protein metabolic processGO:00512462890.104
response to other organismGO:00517072200.103
programmed cell deathGO:00125013920.097
response to nutrient levelsGO:00316673700.097
response to bacteriumGO:00096172000.096
rhythmic processGO:00485111560.095
response to extracellular stimulusGO:00099913800.092
organic acid metabolic processGO:00060822920.090
protein phosphorylationGO:00064683450.088
positive regulation of macromolecule biosynthetic processGO:00105572470.086
response to corticosteroidGO:00319602350.086
regulation of rna metabolic processGO:00512523910.085
transmembrane transportGO:00550854120.083
response to cytokineGO:00340972150.083
nucleic acid templated transcriptionGO:00976593790.082
response to molecule of bacterial originGO:00022371940.081
positive regulation of nitrogen compound metabolic processGO:00511733340.080
response to purine containing compoundGO:00140741260.077
rna biosynthetic processGO:00327743800.077
regulation of phosphorus metabolic processGO:00511743490.075
oxidation reduction processGO:00551143040.074
regulation of transcription dna templatedGO:00063553740.074
response to estradiolGO:00323551640.074
regulation of catalytic activityGO:00507903040.072
cellular response to endogenous stimulusGO:00714953770.070
positive regulation of cellular biosynthetic processGO:00313282950.068
transcription from rna polymerase ii promoterGO:00063662520.068
intracellular signal transductionGO:00355563140.067
single organism biosynthetic processGO:00447113420.066
regulation of cellular component movementGO:00512701500.066
regulation of rna biosynthetic processGO:20011413810.064
cellular response to oxygen containing compoundGO:19017013860.064
positive regulation of nucleobase containing compound metabolic processGO:00459353190.064
response to peptideGO:19016522920.064
cellular response to stressGO:00335542690.064
regulation of cell developmentGO:00602842630.063
regulation of phosphate metabolic processGO:00192203490.062
cell projection organizationGO:00300303020.058
response to oxygen levelsGO:00704822650.058
apoptotic processGO:00069153810.058
positive regulation of phosphorylationGO:00423271770.056
positive regulation of developmental processGO:00510942830.056
Mouse
positive regulation of cellular component organizationGO:00511302000.055
Mouse
cellular response to organic cyclic compoundGO:00714072020.055
regulation of apoptotic processGO:00429813350.054
lipid biosynthetic processGO:00086101280.054
response to vitaminGO:00332731310.054
response to radiationGO:00093141370.053
positive regulation of phosphorus metabolic processGO:00105622620.051
oxoacid metabolic processGO:00434362900.050
response to external biotic stimulusGO:00432072210.050
regulation of protein modification processGO:00313991940.050
negative regulation of macromolecule metabolic processGO:00106052600.049
positive regulation of gene expressionGO:00106282440.049
positive regulation of cell differentiationGO:00455972170.049
Mouse
carboxylic acid metabolic processGO:00197522890.049
response to organophosphorusGO:00466831020.048
circulatory system processGO:00030131830.048
regulation of phosphorylationGO:00423252480.048
positive regulation of transcription dna templatedGO:00458931970.047
multi organism reproductive processGO:00447032620.047
neuron differentiationGO:00301823680.047
cellular response to cytokine stimulusGO:00713451270.046
regulation of cellular component organizationGO:00511283680.046
Mouse
single organism catabolic processGO:00447122830.046
regulation of multicellular organismal developmentGO:20000263760.046
regulation of ion transportGO:00432692450.046
ion transmembrane transportGO:00342203650.045
cellular component biogenesisGO:00440853680.045
positive regulation of rna biosynthetic processGO:19026801970.045
cellular catabolic processGO:00442482950.045
secretion by cellGO:00329402480.044
single organism reproductive processGO:00447022970.044
regulation of cell differentiationGO:00455953200.044
Mouse
cation transportGO:00068123820.044
circadian rhythmGO:0007623880.044
negative regulation of macromolecule biosynthetic processGO:00105581480.044
positive regulation of cell migrationGO:0030335960.043
regulation of cellular protein metabolic processGO:00322682670.043
positive regulation of phosphate metabolic processGO:00459372620.043
chemical homeostasisGO:00488782920.043
defense responseGO:00069521940.043
negative regulation of nitrogen compound metabolic processGO:00511721610.043
nitrogen compound transportGO:00717052290.042
negative regulation of biosynthetic processGO:00098901680.041
response to lipopolysaccharideGO:00324961910.041
cellular response to nitrogen compoundGO:19016992100.041
organophosphate biosynthetic processGO:00904071430.040
regulation of secretionGO:00510462240.040
neuron developmentGO:00486662860.040
secretionGO:00469033070.040
rna metabolic processGO:00160704060.040
response to estrogenGO:00436272320.040
transcription dna templatedGO:00063513770.040
response to tumor necrosis factorGO:0034612560.040
negative regulation of metabolic processGO:00098923310.039
positive regulation of biosynthetic processGO:00098913190.039
neuron projection developmentGO:00311752730.039
reproductive structure developmentGO:00486081280.039
response to inorganic substanceGO:00100353770.039
regulation of nervous system developmentGO:00519602640.038
regulation of intracellular signal transductionGO:19025312180.038
response to temperature stimulusGO:0009266940.038
negative regulation of gene expressionGO:00106291990.038
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.037
cellular ketone metabolic processGO:0042180510.037
response to interleukin 1GO:0070555550.037
response to campGO:0051591910.037
positive regulation of rna metabolic processGO:00512542030.036
negative regulation of nucleic acid templated transcriptionGO:19035071170.036
homeostatic processGO:00425923310.036
reproductive system developmentGO:00614581280.035
response to hypoxiaGO:00016662310.035
protein complex subunit organizationGO:00718223020.034
cellular component assemblyGO:00226073600.034
macromolecular complex assemblyGO:00650032730.034
catabolic processGO:00090563510.034
response to ketoneGO:19016541820.033
carbohydrate derivative metabolic processGO:19011353460.033
response to decreased oxygen levelsGO:00362932370.033
response to metal ionGO:00100382530.033
ribose phosphate metabolic processGO:00196932350.033
regulation of hormone levelsGO:00108171870.033
response to dexamethasoneGO:0071548490.033
cellular response to external stimulusGO:00714961180.032
regulation of neuron differentiationGO:00456642080.032
response to oxidative stressGO:00069791860.032
organic substance catabolic processGO:19015753160.032
negative regulation of cellular metabolic processGO:00313242810.032
positive regulation of cellular component movementGO:00512721020.032
cellular amino acid metabolic processGO:00065201070.032
regulation of cellular localizationGO:00603412630.032
negative regulation of cellular protein metabolic processGO:00322691060.031
response to peptide hormoneGO:00434342780.031
anatomical structure morphogenesisGO:00096532980.031
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063572340.031
response to mechanical stimulusGO:00096121340.030
multicellular organismal reproductive processGO:00486092330.030
vesicle mediated transportGO:00161921810.030
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.030
negative regulation of multicellular organismal processGO:00512412030.030
positive regulation of catalytic activityGO:00430851840.030
gland developmentGO:00487321550.030
development of primary sexual characteristicsGO:00451371070.029
response to acid chemicalGO:00011012220.029
neurological system processGO:00508772190.029
positive regulation of molecular functionGO:00440932300.029
protein oligomerizationGO:00512591910.029
regulation of secretion by cellGO:19035302080.028
proteolysisGO:00065081750.028
positive regulation of cellular protein metabolic processGO:00322701670.028
metal ion transportGO:00300012890.028
positive regulation of protein phosphorylationGO:00019341350.028
regulation of fat cell differentiationGO:004559830.028
negative regulation of developmental processGO:00510931250.028
cellular response to organonitrogen compoundGO:00714171970.028
negative regulation of molecular functionGO:00440921330.028
regulation of transferase activityGO:00513381230.028
protein complex assemblyGO:00064612630.028
regulation of cellular amino acid metabolic processGO:000652120.028
reactive oxygen species metabolic processGO:0072593370.028
negative regulation of transportGO:00510511360.028
regulation of protein phosphorylationGO:00019321830.027
cellular amine metabolic processGO:0044106380.027
synaptic transmissionGO:00072682350.027
negative regulation of nucleobase containing compound metabolic processGO:00459341530.027
cellular response to peptideGO:19016531330.027
response to alkaloidGO:00432791320.027
cation transmembrane transportGO:00986552630.027
regulation of neurogenesisGO:00507672470.027
organophosphate metabolic processGO:00196373700.027
gonad developmentGO:00084061040.027
negative regulation of rna metabolic processGO:00512531230.026
regulation of anatomical structure morphogenesisGO:00226031410.026
Mouse
positive regulation of neurogenesisGO:00507691650.026
regulation of metal ion transportGO:00109591180.026
ossificationGO:0001503700.026
central nervous system developmentGO:00074173110.026
multicellular organism reproductionGO:00325042330.026
positive regulation of protein modification processGO:00314011420.026
response to toxic substanceGO:00096361330.025
female pregnancyGO:00075651220.025
small molecule biosynthetic processGO:00442831240.025
cellular response to peptide hormone stimulusGO:00713751200.025
neuron deathGO:00709971270.025
multi multicellular organism processGO:00447061380.025
carbohydrate metabolic processGO:00059751300.025
regulation of cell projection organizationGO:00313441750.025
response to light stimulusGO:0009416520.025
amino acid transportGO:0006865700.024
blood circulationGO:00080151830.024
inorganic cation transmembrane transportGO:00986622020.024
positive regulation of nucleic acid templated transcriptionGO:19035081970.024
cation homeostasisGO:00550801950.024
response to monosaccharideGO:00342841590.024
regulation of programmed cell deathGO:00430673410.024
head developmentGO:00603222470.024
reproductionGO:00000032450.024
negative regulation of transcription dna templatedGO:00458921160.023
macromolecular complex subunit organizationGO:00439333390.023
positive regulation of nervous system developmentGO:00519621780.023
multicellular organism growthGO:003526410.023
regulation of kinase activityGO:00435491170.023
organic anion transportGO:00157111320.023
positive regulation of transportGO:00510502450.023
intracellular transportGO:00469071850.023
positive regulation of cell motilityGO:2000147970.023
agingGO:00075682410.023
inorganic ion transmembrane transportGO:00986602290.023
positive regulation of cell developmentGO:00107201760.023
divalent inorganic cation transportGO:00725111340.022
amine metabolic processGO:0009308380.022
mapk cascadeGO:00001651400.022
negative regulation of cellular biosynthetic processGO:00313271610.022
regulation of cell proliferationGO:00421273590.022
muscle system processGO:00030121150.022
nucleoside phosphate metabolic processGO:00067532830.022
anion transportGO:00068201780.022
positive regulation of response to stimulusGO:00485842850.022
positive regulation of locomotionGO:00400171020.022
regenerationGO:00310991630.022
response to glucoseGO:00097491360.021
regulation of protein kinase activityGO:00458591050.021
protein complex biogenesisGO:00702712630.021
regulation of response to stressGO:00801341260.021
glycosyl compound metabolic processGO:19016571820.021
purine nucleotide metabolic processGO:00061632290.021
response to mineralocorticoidGO:0051385490.021
carboxylic acid transportGO:00469421150.021
response to increased oxygen levelsGO:0036296450.021
organ regenerationGO:00311001010.021
regulation of cellular amine metabolic processGO:003323880.020
regulation of ossificationGO:0030278320.020
locomotionGO:00400112370.020
response to hexoseGO:00097461440.020
circulatory system developmentGO:00723591340.020
potassium ion transportGO:0006813970.020
response to amino acidGO:0043200750.020
positive regulation of secretion by cellGO:19035321280.020
cellular chemical homeostasisGO:00550822470.020
organic acid transportGO:00158491160.020
response to carbohydrateGO:00097431830.019
positive regulation of cell projection organizationGO:00313461110.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
positive regulation of protein metabolic processGO:00512471780.019
immune system processGO:00023762040.019
sexual reproductionGO:00199531480.019
cellular response to extracellular stimulusGO:0031668730.019
regulation of immune system processGO:00026821230.019
positive regulation of cell proliferationGO:00082842490.019
positive regulation of cellular catabolic processGO:0031331710.019
dna metabolic processGO:0006259960.019
tissue developmentGO:00098882520.019
cell motilityGO:00488702020.019
membrane organizationGO:0061024940.019
positive regulation of apoptotic processGO:00430651540.019
positive regulation of cellular amine metabolic processGO:003324030.019
cytokine mediated signaling pathwayGO:0019221430.019
positive regulation of neuron projection developmentGO:0010976990.019
cellular homeostasisGO:00197252520.019
regulation of cellular ketone metabolic processGO:0010565270.018
regulation of cell motilityGO:20001451310.018
jak stat cascadeGO:0007259260.018
developmental process involved in reproductionGO:00030061590.018
regulation of signal transductionGO:00099663180.018
cellular protein localizationGO:00346131220.018
sex differentiationGO:00075481130.018
purine containing compound biosynthetic processGO:0072522850.018
response to woundingGO:00096112540.018
hormone metabolic processGO:0042445690.018
response to ethanolGO:00454711620.018
nucleotide metabolic processGO:00091172790.018
behaviorGO:00076102050.018
establishment of protein localizationGO:00451841410.017
divalent metal ion transportGO:00708381320.017
alcohol metabolic processGO:0006066770.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.017
response to growth factorGO:00708481890.017
regulation of response to external stimulusGO:00321011060.017
macromolecule localizationGO:00330362520.017
organelle organizationGO:00069962660.017
negative regulation of rna biosynthetic processGO:19026791180.017
positive regulation of kinase activityGO:0033674770.017
regulation of transmembrane transportGO:00347621220.017
localization of cellGO:00516742020.017
regulation of immunoglobulin productionGO:000263740.017
positive regulation of secretionGO:00510471400.017
positive regulation of cell deathGO:00109421840.017
ribonucleotide metabolic processGO:00092592310.017
response to vitamin dGO:0033280340.017
response to corticosteroneGO:0051412400.017
cellular response to interleukin 1GO:0071347370.016
regulation of anatomical structure sizeGO:00900661350.016
positive regulation of isotype switchingGO:004583010.016
response to nicotineGO:0035094510.016
ion homeostasisGO:00508012120.016
protein homooligomerizationGO:0051260910.016
positive regulation of catabolic processGO:0009896780.016
female gonad developmentGO:0008585530.016
regulation of hydrolase activityGO:00513361430.016
response to heatGO:0009408600.016
cellular response to biotic stimulusGO:0071216590.016
peptidyl amino acid modificationGO:00181931260.015
negative regulation of apoptotic processGO:00430661810.015
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.015
vascular process in circulatory systemGO:0003018960.015
negative regulation of response to stimulusGO:00485851550.015
cell projection morphogenesisGO:00488581230.015
neuron neuron synaptic transmissionGO:0007270600.015
cellular response to molecule of bacterial originGO:0071219560.015
positive regulation of intracellular signal transductionGO:19025331380.015
organic hydroxy compound metabolic processGO:19016151150.015
negative regulation of programmed cell deathGO:00430691830.015
positive regulation of programmed cell deathGO:00430681570.015
purine containing compound metabolic processGO:00725212530.015
regulation of system processGO:00440572080.015
positive regulation of immunoglobulin productionGO:000263940.015
positive regulation of signalingGO:00230562700.015
positive regulation of protein kinase activityGO:0045860730.015
regulation of locomotionGO:00400121480.014
single organism membrane organizationGO:0044802740.014
cellular response to abiotic stimulusGO:0071214850.014
positive regulation of transferase activityGO:0051347810.014
cofactor metabolic processGO:0051186950.014
calcium ion transportGO:00068161310.014
inflammatory responseGO:00069541500.014
negative regulation of cell deathGO:00605482290.014
gamete generationGO:00072761240.014
purine ribonucleoside metabolic processGO:00461281680.014
regulation of homeostatic processGO:00328441010.014
positive regulation of nucleoside metabolic processGO:0045979550.014
cell cycle checkpointGO:000007520.014
cell activationGO:0001775970.014
purine nucleoside metabolic processGO:00422781690.014
anion transmembrane transportGO:0098656770.014
nucleobase containing small molecule metabolic processGO:00550863160.014
eye developmentGO:0001654500.014
protein processingGO:0016485680.014
cellular response to growth factor stimulusGO:00713631620.014
eye morphogenesisGO:004859240.013
regulation of cell migrationGO:00303341280.013
brain developmentGO:00074202470.013
regulation of cell growthGO:0001558850.013
response to reactive oxygen speciesGO:00003021200.013
regulation of nucleotide catabolic processGO:0030811650.013
response to hyperoxiaGO:0055093450.013
purine containing compound catabolic processGO:00725231380.013
regulation of smooth muscle cell proliferationGO:0048660750.013
smooth muscle cell proliferationGO:0048659770.013
negative regulation of cell differentiationGO:0045596990.013
response to hydrogen peroxideGO:0042542890.013
single organism intracellular transportGO:19025821660.013
axis specificationGO:000979840.013
nucleoside metabolic processGO:00091161790.013
positive regulation of cell growthGO:0030307440.013
response to vitamin eGO:0033197240.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
cell migrationGO:00164771970.013
cellular response to lipopolysaccharideGO:0071222550.013
carbohydrate derivative biosynthetic processGO:19011371240.013
cellular response to nutrient levelsGO:0031669600.013
positive regulation of purine nucleotide metabolic processGO:1900544910.013
biological adhesionGO:00226101100.013
positive regulation of neuron differentiationGO:00456661260.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
response to transition metal nanoparticleGO:19902671220.013
regulation of neuron projection developmentGO:00109751610.012
single organism behaviorGO:00447081300.012
embryonic placenta developmentGO:000189210.012
regulation of neuron deathGO:19012141150.012
glycogen metabolic processGO:0005977230.012
regulation of mapk cascadeGO:00434081160.012
divalent inorganic cation homeostasisGO:00725071650.012
ovulation cycleGO:0042698670.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
regulation of potassium ion transportGO:0043266290.012
negative regulation of neurogenesisGO:0050768780.012
ovulation cycle processGO:0022602500.012
cellular lipid metabolic processGO:00442552080.012
regulation of body fluid levelsGO:0050878900.012
synaptic growth at neuromuscular junctionGO:005112410.012
regulation of catabolic processGO:00098941130.012
positive regulation of purine nucleotide catabolic processGO:0033123530.012
regulation of blood circulationGO:19035221100.012
bmp signaling pathwayGO:003050940.012
macroautophagyGO:001623640.012
regulation of ion transmembrane transportGO:00347651210.012
single organism carbohydrate metabolic processGO:00447231180.012
coenzyme metabolic processGO:0006732860.012
regulation of purine nucleotide catabolic processGO:0033121650.012
negative regulation of innate immune responseGO:004582440.012
lens fiber cell differentiationGO:007030630.012
cellular response to lipidGO:00713962010.012
regulation of blood pressureGO:0008217830.012
metal ion homeostasisGO:00550651860.012
l glutamate importGO:005193820.012
organonitrogen compound catabolic processGO:19015651790.012
vasoconstrictionGO:0042310540.011
purine ribonucleotide metabolic processGO:00091502270.011
negative regulation of catalytic activityGO:00430861030.011
nucleoside triphosphate metabolic processGO:00091411440.011
defense response to gram negative bacteriumGO:005082930.011
regulation of immune responseGO:0050776550.011
negative regulation of collagen biosynthetic processGO:003296640.011
sulfur compound metabolic processGO:0006790700.011
calcium ion transmembrane transportGO:0070588700.011
gastrulationGO:000736920.011
negative regulation of cell communicationGO:00106481580.011
regulation of growthGO:00400081050.011
nucleobase containing compound catabolic processGO:00346551520.011
regulation of cell adhesionGO:0030155520.011
negative regulation of cell proliferationGO:00082851190.011
organic hydroxy compound transportGO:0015850770.011
regulation of transporter activityGO:0032409500.011
response to ammonium ionGO:0060359710.011
regulation of calcium ion transportGO:0051924770.011
regulation of purine nucleotide metabolic processGO:19005421150.011
response to progesteroneGO:0032570480.011
regulation of dna metabolic processGO:0051052600.011
monovalent inorganic cation transportGO:00156721720.011
meiotic cell cycle processGO:190304630.011
negative regulation of protein metabolic processGO:00512481140.011
regulation of synaptic transmissionGO:00508041410.011
glycosyl compound catabolic processGO:19016581260.011
camera type eye morphogenesisGO:004859320.011
amide transportGO:00428861050.011
hormone transportGO:00099141210.011
response to retinoic acidGO:0032526630.011
reactive oxygen species biosynthetic processGO:190340980.011
cell adhesionGO:00071551100.011
axon developmentGO:0061564960.011
muscle cell proliferationGO:0033002840.011
protein localizationGO:00081041910.011
autophagic cell deathGO:004810240.011
cardiovascular system developmentGO:00723581340.011
regulation of protein serine threonine kinase activityGO:0071900640.011
somatic diversification of immunoglobulins involved in immune responseGO:000220810.011
protein heterooligomerizationGO:0051291890.011
cell cycleGO:00070491010.011
ras protein signal transductionGO:0007265290.010
wound healingGO:00420601220.010
negative regulation of neuron differentiationGO:0045665620.010
negative regulation of neuron deathGO:1901215690.010
protein maturationGO:0051604680.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
negative regulation of osteoblast differentiationGO:004566820.010
cell morphogenesis involved in differentiationGO:00009041190.010
defense response to gram positive bacteriumGO:005083020.010
cellular response to alcoholGO:0097306870.010
renal system developmentGO:0072001670.010
b cell activation involved in immune responseGO:000231210.010
negative regulation of cell developmentGO:0010721820.010
cellular response to tumor necrosis factorGO:0071356460.010
regulation of blood vessel sizeGO:0050880890.010
neuron projection morphogenesisGO:00488121220.010
protein transportGO:00150311320.010
cognitionGO:0050890920.010
positive regulation of mapk cascadeGO:0043410920.010
pteridine containing compound metabolic processGO:0042558140.010
regulation of protein maturationGO:1903317500.010
response to starvationGO:0042594590.010

Gdf15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.022
disease of anatomical entityDOID:700.022
disease of metabolismDOID:001466700.020
inherited metabolic disorderDOID:65500.020
nervous system diseaseDOID:86300.017
sensory system diseaseDOID:005015500.011
bone diseaseDOID:008000100.010
connective tissue diseaseDOID:6500.010