Rattus norvegicus

102 known processes

Ikbkb

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

(Aliases: AIM-1,IKK2)

Ikbkb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecular complex subunit organizationGO:00439333390.157
regulation of transcription from rna polymerase ii promoterGO:00063572340.128
Human
rna biosynthetic processGO:00327743800.127
positive regulation of response to stimulusGO:00485842850.103
Fly
macromolecular complex assemblyGO:00650032730.087
protein complex subunit organizationGO:00718223020.083
response to external biotic stimulusGO:00432072210.078
Fly
transcription from rna polymerase ii promoterGO:00063662520.076
Human
secretionGO:00469033070.070
positive regulation of nitrogen compound metabolic processGO:00511733340.069
Human Fly
regulation of immune system processGO:00026821230.067
Fly
nucleic acid templated transcriptionGO:00976593790.066
response to woundingGO:00096112540.065
cellular component assemblyGO:00226073600.065
protein oligomerizationGO:00512591910.063
negative regulation of cellular metabolic processGO:00313242810.063
rna metabolic processGO:00160704060.061
negative regulation of nitrogen compound metabolic processGO:00511721610.058
immune system processGO:00023762040.057
Mouse Fly
cellular component biogenesisGO:00440853680.056
regulation of molecular functionGO:00650093980.056
positive regulation of cellular biosynthetic processGO:00313282950.055
Human Fly
positive regulation of protein metabolic processGO:00512471780.053
regulation of transcription dna templatedGO:00063553740.051
regulation of rna biosynthetic processGO:20011413810.051
positive regulation of biosynthetic processGO:00098913190.051
Human Fly
cellular response to oxygen containing compoundGO:19017013860.051
response to metal ionGO:00100382530.050
regulation of cell proliferationGO:00421273590.049
protein localizationGO:00081041910.049
protein complex assemblyGO:00064612630.049
regulation of protein metabolic processGO:00512462890.049
organelle organizationGO:00069962660.047
cation transportGO:00068123820.046
Mouse
cellular response to lipidGO:00713962010.045
cellular response to nitrogen compoundGO:19016992100.044
regulation of signal transductionGO:00099663180.044
Human
neuron differentiationGO:00301823680.044
regulation of programmed cell deathGO:00430673410.043
nitrogen compound transportGO:00717052290.043
positive regulation of cellular protein metabolic processGO:00322701670.042
response to bacteriumGO:00096172000.041
Fly
cellular response to endogenous stimulusGO:00714953770.041
catabolic processGO:00090563510.041
Fly
metal ion transportGO:00300012890.041
Mouse
protein complex biogenesisGO:00702712630.040
positive regulation of signalingGO:00230562700.040
programmed cell deathGO:00125013920.039
neurological system processGO:00508772190.038
positive regulation of gene expressionGO:00106282440.037
Human
regulation of protein transportGO:0051223680.037
regulation of nucleic acid templated transcriptionGO:19035063800.037
secretion by cellGO:00329402480.036
localization of cellGO:00516742020.036
transcription dna templatedGO:00063513770.035
anatomical structure morphogenesisGO:00096532980.035
regulation of cell projection organizationGO:00313441750.035
positive regulation of nucleobase containing compound metabolic processGO:00459353190.034
Human
positive regulation of immune system processGO:0002684900.034
Fly
protein transportGO:00150311320.034
apoptotic processGO:00069153810.034
positive regulation of cell communicationGO:00106472710.034
response to other organismGO:00517072200.034
Fly
positive regulation of transcription dna templatedGO:00458931970.034
Human
cell cell signalingGO:00072673350.033
regulation of intracellular signal transductionGO:19025312180.033
Human
response to hexoseGO:00097461440.033
response to lipopolysaccharideGO:00324961910.033
regulation of catalytic activityGO:00507903040.032
positive regulation of intracellular signal transductionGO:19025331380.031
regulation of cellular localizationGO:00603412630.031
neuron projection developmentGO:00311752730.031
regulation of cellular ketone metabolic processGO:0010565270.031
intracellular signal transductionGO:00355563140.031
Mouse
cellular ketone metabolic processGO:0042180510.031
cellular amino acid metabolic processGO:00065201070.031
cellular amine metabolic processGO:0044106380.030
positive regulation of phosphate metabolic processGO:00459372620.030
regulation of protein phosphorylationGO:00019321830.030
cellular response to biotic stimulusGO:0071216590.030
defense responseGO:00069521940.030
Fly
single organism organelle organizationGO:19025891800.030
negative regulation of metabolic processGO:00098923310.029
positive regulation of signal transductionGO:00099671750.029
regulation of cellular protein metabolic processGO:00322682670.029
positive regulation of cell deathGO:00109421840.029
action potentialGO:0001508540.029
positive regulation of molecular functionGO:00440932300.028
response to inorganic substanceGO:00100353770.028
cell migrationGO:00164771970.028
response to biotic stimulusGO:00096072260.027
Fly
carboxylic acid metabolic processGO:00197522890.027
regulation of apoptotic processGO:00429813350.027
cellular response to stressGO:00335542690.026
negative regulation of macromolecule metabolic processGO:00106052600.026
regulation of protein modification processGO:00313991940.026
regulation of cellular amine metabolic processGO:003323880.026
regulation of multicellular organismal developmentGO:20000263760.025
regulation of cell differentiationGO:00455953200.025
regulation of secretion by cellGO:19035302080.025
negative regulation of biosynthetic processGO:00098901680.025
cellular response to organic cyclic compoundGO:00714072020.025
wound healingGO:00420601220.025
macromolecule localizationGO:00330362520.025
regulation of immunoglobulin productionGO:000263740.024
proteolysisGO:00065081750.024
positive regulation of phosphorylationGO:00423271770.024
regulation of phosphate metabolic processGO:00192203490.024
positive regulation of phosphorus metabolic processGO:00105622620.024
regulation of phosphorylationGO:00423252480.024
cellular chemical homeostasisGO:00550822470.024
head developmentGO:00603222470.023
cellular response to organonitrogen compoundGO:00714171970.023
regulation of neurogenesisGO:00507672470.023
immune responseGO:00069551040.023
Fly
cellular component morphogenesisGO:00329891550.023
cell activationGO:0001775970.023
negative regulation of macromolecule biosynthetic processGO:00105581480.023
response to cytokineGO:00340972150.023
Human
positive regulation of programmed cell deathGO:00430681570.022
vesicle mediated transportGO:00161921810.022
protein phosphorylationGO:00064683450.022
Human Mouse Fly
establishment of protein localizationGO:00451841410.022
brain developmentGO:00074202470.022
cytoskeleton organizationGO:00070101110.022
regulation of membrane potentialGO:00423911100.022
response to peptideGO:19016522920.022
positive regulation of multicellular organismal processGO:00512403870.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.022
multi organism reproductive processGO:00447032620.021
regulation of system processGO:00440572080.021
regulation of cellular amino acid metabolic processGO:000652120.021
amine metabolic processGO:0009308380.021
agingGO:00075682410.021
nucleoside phosphate metabolic processGO:00067532830.021
oxoacid metabolic processGO:00434362900.021
mononuclear cell proliferationGO:0032943290.021
multicellular organismal signalingGO:0035637440.021
reproductive processGO:00224143720.021
multicellular organism reproductionGO:00325042330.021
regulation of cell developmentGO:00602842630.021
regulation of rna metabolic processGO:00512523910.021
positive regulation of rna metabolic processGO:00512542030.021
Human
regulation of cellular component organizationGO:00511283680.021
response to molecule of bacterial originGO:00022371940.021
positive regulation of macromolecule biosynthetic processGO:00105572470.021
Human
homeostatic processGO:00425923310.020
Mouse
positive regulation of protein modification processGO:00314011420.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
Human
purine containing compound metabolic processGO:00725212530.020
positive regulation of catalytic activityGO:00430851840.020
positive regulation of cell proliferationGO:00082842490.020
negative regulation of multicellular organismal processGO:00512412030.020
cell projection organizationGO:00300303020.020
positive regulation of cell differentiationGO:00455972170.020
signal releaseGO:00230611450.020
positive regulation of nucleic acid templated transcriptionGO:19035081970.020
Human
regulation of transferase activityGO:00513381230.020
neuron developmentGO:00486662860.020
cell type specific apoptotic processGO:00972851340.020
regulation of establishment of protein localizationGO:0070201690.020
negative regulation of cell proliferationGO:00082851190.020
regulation of phosphorus metabolic processGO:00511743490.020
regulation of neuron differentiationGO:00456642080.020
cellular response to molecule of bacterial originGO:0071219560.019
response to alkaloidGO:00432791320.019
protein heterooligomerizationGO:0051291890.019
response to peptide hormoneGO:00434342780.019
regulation of neuron projection developmentGO:00109751610.019
divalent inorganic cation transportGO:00725111340.019
organic acid metabolic processGO:00060822920.019
regulation of secretionGO:00510462240.019
chemical homeostasisGO:00488782920.019
central nervous system developmentGO:00074173110.019
regulation of nervous system developmentGO:00519602640.019
gastrulationGO:000736920.019
cellular component movementGO:00069282480.019
positive regulation of protein phosphorylationGO:00019341350.019
positive regulation of cell developmentGO:00107201760.018
mesoderm developmentGO:000749820.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
spindle organizationGO:000705120.018
mapk cascadeGO:00001651400.018
regulation of protein localizationGO:0032880810.018
reproductionGO:00000032450.018
leukocyte activationGO:0045321760.018
response to glucoseGO:00097491360.018
epithelial cell differentiationGO:0030855710.018
regulation of ion transportGO:00432692450.018
Mouse
immune effector processGO:0002252530.018
Fly
amide transportGO:00428861050.018
regulation of cell motilityGO:20001451310.018
multicellular organismal reproductive processGO:00486092330.018
positive regulation of cellular amine metabolic processGO:003324030.018
blood circulationGO:00080151830.018
formation of primary germ layerGO:000170410.017
negative regulation of cell deathGO:00605482290.017
nucleobase containing small molecule metabolic processGO:00550863160.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
neuronal action potentialGO:0019228350.017
single organism cellular localizationGO:19025801020.017
regulation of hormone levelsGO:00108171870.017
purine ribonucleotide metabolic processGO:00091502270.017
tube developmentGO:0035295890.017
immune system developmentGO:0002520410.017
positive regulation of transportGO:00510502450.017
Mouse
axis specificationGO:000979840.017
response to oxidative stressGO:00069791860.016
positive regulation of rna biosynthetic processGO:19026801970.016
Human
cellular homeostasisGO:00197252520.016
asymmetric protein localizationGO:000810520.016
cell morphogenesis involved in differentiationGO:00009041190.016
actin filament based processGO:0030029860.016
positive regulation of nervous system developmentGO:00519621780.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
regulation of leukocyte activationGO:0002694450.016
lymphocyte activationGO:0046649430.016
antigen processing and presentationGO:001988220.016
inflammatory responseGO:00069541500.016
positive regulation of neurogenesisGO:00507691650.016
response to corticosteroidGO:00319602350.016
response to monosaccharideGO:00342841590.015
nucleotide metabolic processGO:00091172790.015
regulation of immune effector processGO:0002697320.015
Fly
response to extracellular stimulusGO:00099913800.015
leukocyte differentiationGO:0002521300.015
regulation of response to stressGO:00801341260.015
Fly
regulation of cell morphogenesisGO:0022604770.015
calcium ion transportGO:00068161310.015
positive regulation of immune responseGO:0050778420.015
Fly
metal ion homeostasisGO:00550651860.015
negative regulation of rna metabolic processGO:00512531230.015
response to glucocorticoidGO:00513842230.015
protein homooligomerizationGO:0051260910.015
response to organophosphorusGO:00466831020.015
cellular response to peptideGO:19016531330.015
response to carbohydrateGO:00097431830.015
response to radiationGO:00093141370.015
negative regulation of cellular biosynthetic processGO:00313271610.015
carbohydrate derivative metabolic processGO:19011353460.015
ribose phosphate metabolic processGO:00196932350.015
single organism intracellular transportGO:19025821660.015
positive regulation of apoptotic processGO:00430651540.015
cellular catabolic processGO:00442482950.015
regulation of metal ion transportGO:00109591180.014
Mouse
peptide transportGO:0015833970.014
protein catabolic processGO:0030163300.014
Fly
positive regulation of cellular component organizationGO:00511302000.014
regulation of kinase activityGO:00435491170.014
mitotic spindle organizationGO:000705220.014
organonitrogen compound biosynthetic processGO:19015661670.014
Fly
synaptic growth at neuromuscular junctionGO:005112410.014
single organism reproductive processGO:00447022970.014
ion homeostasisGO:00508012120.014
lymphocyte homeostasisGO:000226020.014
Mouse
negative regulation of gene expressionGO:00106291990.014
multi multicellular organism processGO:00447061380.014
regulation of protein kinase activityGO:00458591050.014
regulation of locomotionGO:00400121480.014
response to ketoneGO:19016541820.014
sensory organ developmentGO:0007423740.014
organic substance catabolic processGO:19015753160.014
Fly
cellular response to cytokine stimulusGO:00713451270.014
Human
gland developmentGO:00487321550.014
tissue developmentGO:00098882520.014
purine nucleotide metabolic processGO:00061632290.014
negative regulation of innate immune responseGO:004582440.014
response to hypoxiaGO:00016662310.013
cellular response to growth factor stimulusGO:00713631620.013
negative regulation of molecular functionGO:00440921330.013
negative regulation of protein metabolic processGO:00512481140.013
gamete generationGO:00072761240.013
dephosphorylationGO:0016311980.013
cellular response to peptide hormone stimulusGO:00713751200.013
positive regulation of secretion by cellGO:19035321280.013
negative regulation of cell differentiationGO:0045596990.013
developmental growthGO:00485891000.013
hormone secretionGO:00468791150.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.013
divalent inorganic cation homeostasisGO:00725071650.013
lipid metabolic processGO:00066292830.013
cytokine productionGO:0001816610.013
regulation of leukocyte proliferationGO:0070663260.013
cell morphogenesisGO:00009021420.013
regulation of body fluid levelsGO:0050878900.013
negative regulation of apoptotic processGO:00430661810.013
response to growth factorGO:00708481890.013
transmembrane transportGO:00550854120.013
Mouse
rhythmic processGO:00485111560.013
b cell differentiationGO:003018320.013
response to decreased oxygen levelsGO:00362932370.013
positive regulation of secretionGO:00510471400.013
negative regulation of transcription dna templatedGO:00458921160.013
transmission of nerve impulseGO:0019226420.013
synaptic transmissionGO:00072682350.013
signal transduction by phosphorylationGO:00230141440.013
lipid storageGO:001991510.013
regulation of lymphocyte proliferationGO:0050670260.013
hormone transportGO:00099141210.013
response to transition metal nanoparticleGO:19902671220.013
cellular response to hormone stimulusGO:00328702470.013
regulation of blood circulationGO:19035221100.012
lymphocyte proliferationGO:0046651290.012
neuron projection morphogenesisGO:00488121220.012
cytoskeleton dependent cytokinesisGO:006164020.012
organophosphate metabolic processGO:00196373700.012
smooth muscle cell proliferationGO:0048659770.012
cell projection morphogenesisGO:00488581230.012
single organism membrane organizationGO:0044802740.012
regulation of immune responseGO:0050776550.012
Fly
male gamete generationGO:0048232990.012
spermatogenesisGO:0007283990.012
negative regulation of cell developmentGO:0010721820.012
response to mechanical stimulusGO:00096121340.012
ion transmembrane transportGO:00342203650.012
Mouse
ribonucleotide metabolic processGO:00092592310.012
hematopoietic or lymphoid organ developmentGO:0048534360.012
organonitrogen compound catabolic processGO:19015651790.012
positive regulation of neuron differentiationGO:00456661260.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
inorganic ion transmembrane transportGO:00986602290.012
regulation of cellular component movementGO:00512701500.012
regulation of mapk cascadeGO:00434081160.012
negative regulation of transportGO:00510511360.012
single organism biosynthetic processGO:00447113420.012
response to oxygen levelsGO:00704822650.011
negative regulation of programmed cell deathGO:00430691830.011
developmental process involved in reproductionGO:00030061590.011
response to acid chemicalGO:00011012220.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
reactive oxygen species biosynthetic processGO:190340980.011
response to nutrient levelsGO:00316673700.011
sensory perceptionGO:00076001010.011
meiotic cell cycle processGO:190304630.011
positive regulation of mapk cascadeGO:0043410920.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
regulation of smooth muscle cell proliferationGO:0048660750.011
purine ribonucleoside metabolic processGO:00461281680.011
purine containing compound catabolic processGO:00725231380.011
acute inflammatory responseGO:0002526580.011
intracellular transportGO:00469071850.011
negative regulation of nervous system developmentGO:0051961790.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
cellular response to transforming growth factor beta stimulusGO:0071560410.011
embryonic pattern specificationGO:000988010.011
positive regulation of cell projection organizationGO:00313461110.011
organophosphate biosynthetic processGO:00904071430.011
regulation of cell activationGO:0050865500.011
muscle system processGO:00030121150.011
cellular response to external stimulusGO:00714961180.011
cation transmembrane transportGO:00986552630.011
Mouse
response to ionizing radiationGO:0010212590.011
negative regulation of catalytic activityGO:00430861030.011
glucose homeostasisGO:0042593750.011
reproductive system developmentGO:00614581280.011
cell growthGO:00160491040.011
male sex differentiationGO:0046661640.011
forebrain developmentGO:0030900980.011
response to campGO:0051591910.010
peptidyl amino acid modificationGO:00181931260.010
Human Fly
response to tumor necrosis factorGO:0034612560.010
Human
cell cell signaling involved in cell fate commitmentGO:004516820.010
membrane organizationGO:0061024940.010
negative regulation of rna biosynthetic processGO:19026791180.010
divalent metal ion transportGO:00708381320.010
response to reactive oxygen speciesGO:00003021200.010
circulatory system developmentGO:00723591340.010
cation homeostasisGO:00550801950.010
locomotionGO:00400112370.010
negative regulation of cellular protein metabolic processGO:00322691060.010
defense response to gram negative bacteriumGO:005082930.010
regulation of neuron deathGO:19012141150.010
salivary gland developmentGO:000743130.010
ribonucleoside metabolic processGO:00091191740.010
negative regulation of cell communicationGO:00106481580.010
inorganic cation transmembrane transportGO:00986622020.010
regulation of peptide transportGO:0090087870.010
regulation of reactive oxygen species metabolic processGO:2000377260.010
endoplasmic reticulum organizationGO:000702910.010
protein processingGO:0016485680.010

Ikbkb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.018
nervous system diseaseDOID:86300.018
musculoskeletal system diseaseDOID:1700.012
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.011
gastrointestinal system cancerDOID:311900.010