Rattus norvegicus

56 known processes

Lta4h

leukotriene A4 hydrolase

Lta4h biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.206
carbohydrate metabolic processGO:00059751300.146
single organism catabolic processGO:00447122830.146
response to radiationGO:00093141370.124
oxoacid metabolic processGO:00434362900.115
single organism biosynthetic processGO:00447113420.101
Human
positive regulation of multicellular organismal processGO:00512403870.094
anatomical structure morphogenesisGO:00096532980.089
regulation of catalytic activityGO:00507903040.081
positive regulation of nitrogen compound metabolic processGO:00511733340.075
oxidation reduction processGO:00551143040.073
single organism carbohydrate metabolic processGO:00447231180.072
tube developmentGO:0035295890.069
carbohydrate derivative metabolic processGO:19011353460.068
catabolic processGO:00090563510.063
Human Yeast
cellular amino acid metabolic processGO:00065201070.062
reproductive processGO:00224143720.059
g protein coupled receptor signaling pathwayGO:00071862420.057
secretionGO:00469033070.054
response to extracellular stimulusGO:00099913800.053
regulation of cellular ketone metabolic processGO:0010565270.052
programmed cell deathGO:00125013920.051
carboxylic acid metabolic processGO:00197522890.051
rna metabolic processGO:00160704060.050
behaviorGO:00076102050.050
neuron developmentGO:00486662860.048
lipid metabolic processGO:00066292830.047
multi organism reproductive processGO:00447032620.047
cellular response to nitrogen compoundGO:19016992100.046
cellular ketone metabolic processGO:0042180510.045
positive regulation of developmental processGO:00510942830.041
cellular component movementGO:00069282480.041
positive regulation of protein metabolic processGO:00512471780.041
nitrogen compound transportGO:00717052290.041
rna biosynthetic processGO:00327743800.040
regulation of cellular localizationGO:00603412630.039
developmental process involved in reproductionGO:00030061590.039
response to monosaccharideGO:00342841590.039
tissue developmentGO:00098882520.038
response to metal ionGO:00100382530.038
regulation of protein metabolic processGO:00512462890.038
response to hexoseGO:00097461440.038
single organism reproductive processGO:00447022970.038
circulatory system processGO:00030131830.037
Rat
nucleic acid templated transcriptionGO:00976593790.037
cell growthGO:00160491040.037
reproductionGO:00000032450.036
neuron projection developmentGO:00311752730.036
multicellular organismal reproductive processGO:00486092330.036
regulation of cellular amino acid metabolic processGO:000652120.035
cellular amine metabolic processGO:0044106380.035
gamete generationGO:00072761240.035
vesicle mediated transportGO:00161921810.035
cellular response to endogenous stimulusGO:00714953770.035
positive regulation of macromolecule biosynthetic processGO:00105572470.034
transcription dna templatedGO:00063513770.034
positive regulation of transportGO:00510502450.034
rhythmic processGO:00485111560.034
regulation of rna metabolic processGO:00512523910.034
positive regulation of cell proliferationGO:00082842490.034
homeostatic processGO:00425923310.033
amine metabolic processGO:0009308380.033
cell cell signalingGO:00072673350.033
ribonucleotide catabolic processGO:00092611360.033
ion homeostasisGO:00508012120.033
regulation of cellular component organizationGO:00511283680.033
response to bacteriumGO:00096172000.033
cellular response to stressGO:00335542690.032
positive regulation of cell deathGO:00109421840.032
cellular lipid metabolic processGO:00442552080.032
positive regulation of biosynthetic processGO:00098913190.032
positive regulation of gene expressionGO:00106282440.032
reproductive structure developmentGO:00486081280.032
intracellular signal transductionGO:00355563140.032
regulation of multicellular organismal developmentGO:20000263760.031
response to inorganic substanceGO:00100353770.031
transcription from rna polymerase ii promoterGO:00063662520.031
growthGO:00400071650.031
response to peptideGO:19016522920.031
apoptotic processGO:00069153810.031
regulation of rna biosynthetic processGO:20011413810.030
regulation of growthGO:00400081050.030
protein phosphorylationGO:00064683450.030
synaptic transmissionGO:00072682350.030
negative regulation of signalingGO:00230571570.030
cellular response to hormone stimulusGO:00328702470.029
organonitrogen compound biosynthetic processGO:19015661670.029
neuron differentiationGO:00301823680.029
cytokine productionGO:0001816610.029
negative regulation of response to stimulusGO:00485851550.029
blood circulationGO:00080151830.029
Rat
regulation of molecular functionGO:00650093980.029
cellular carbohydrate metabolic processGO:0044262720.029
establishment of protein localizationGO:00451841410.028
regulation of programmed cell deathGO:00430673410.028
cellular response to peptide hormone stimulusGO:00713751200.028
response to oxidative stressGO:00069791860.028
response to ethanolGO:00454711620.028
response to peptide hormoneGO:00434342780.027
regulation of secretion by cellGO:19035302080.027
organophosphate metabolic processGO:00196373700.027
neuron deathGO:00709971270.027
reproductive system developmentGO:00614581280.027
chemical homeostasisGO:00488782920.026
response to estrogenGO:00436272320.026
regulation of nucleic acid templated transcriptionGO:19035063800.026
neuron projection morphogenesisGO:00488121220.026
secretion by cellGO:00329402480.026
positive regulation of transcription dna templatedGO:00458931970.025
cell motilityGO:00488702020.025
multicellular organism reproductionGO:00325042330.025
developmental growthGO:00485891000.025
monocarboxylic acid metabolic processGO:00327871520.025
response to oxygen levelsGO:00704822650.025
organonitrogen compound catabolic processGO:19015651790.025
Human
negative regulation of cell communicationGO:00106481580.025
cell type specific apoptotic processGO:00972851340.025
negative regulation of cell deathGO:00605482290.024
regulation of secretionGO:00510462240.024
positive regulation of cellular biosynthetic processGO:00313282950.024
circadian rhythmGO:0007623880.024
regulation of cellular protein metabolic processGO:00322682670.024
positive regulation of cellular protein metabolic processGO:00322701670.024
protein localizationGO:00081041910.024
chromosome segregationGO:000705920.024
cardiovascular system developmentGO:00723581340.023
regulation of catabolic processGO:00098941130.023
axon developmentGO:0061564960.023
regulation of signal transductionGO:00099663180.023
cellular response to organonitrogen compoundGO:00714171970.023
regulation of cellular amine metabolic processGO:003323880.023
cell morphogenesis involved in differentiationGO:00009041190.023
negative regulation of programmed cell deathGO:00430691830.023
cellular response to peptideGO:19016531330.022
hexose metabolic processGO:0019318580.022
response to insulinGO:00328681330.022
positive regulation of locomotionGO:00400171020.022
negative regulation of gene expressionGO:00106291990.022
cell projection organizationGO:00300303020.022
sexual reproductionGO:00199531480.021
response to hypoxiaGO:00016662310.021
response to nutrientGO:00075842480.021
wound healingGO:00420601220.021
regulation of transferase activityGO:00513381230.021
response to nutrient levelsGO:00316673700.021
renal system developmentGO:0072001670.021
cation homeostasisGO:00550801950.021
positive regulation of signal transductionGO:00099671750.021
negative regulation of metabolic processGO:00098923310.021
positive regulation of cellular amine metabolic processGO:003324030.021
cellular response to abiotic stimulusGO:0071214850.021
head developmentGO:00603222470.021
response to carbohydrateGO:00097431830.020
regulation of kinase activityGO:00435491170.020
regulation of cell cycleGO:0051726730.020
response to woundingGO:00096112540.020
regulation of neuron deathGO:19012141150.020
cell cycle phase transitionGO:0044770210.020
digestive system developmentGO:0055123410.019
regulation of cell growthGO:0001558850.019
cellular catabolic processGO:00442482950.019
Human
metal ion homeostasisGO:00550651860.019
response to reactive oxygen speciesGO:00003021200.019
regulation of transcription dna templatedGO:00063553740.019
agingGO:00075682410.019
Rat
positive regulation of apoptotic processGO:00430651540.019
response to glucoseGO:00097491360.019
response to decreased oxygen levelsGO:00362932370.019
cellular response to oxygen containing compoundGO:19017013860.019
regulation of neuron apoptotic processGO:0043523830.019
regulation of cell developmentGO:00602842630.019
carbohydrate derivative biosynthetic processGO:19011371240.019
response to alkaloidGO:00432791320.018
response to estradiolGO:00323551640.018
small molecule catabolic processGO:0044282590.018
sex differentiationGO:00075481130.018
regulation of phosphorylationGO:00423252480.018
cellular nitrogen compound catabolic processGO:00442701630.018
response to external biotic stimulusGO:00432072210.018
ossificationGO:0001503700.018
kidney developmentGO:0001822670.017
locomotionGO:00400112370.017
purine containing compound metabolic processGO:00725212530.017
blood vessel developmentGO:0001568690.017
circulatory system developmentGO:00723591340.017
response to other organismGO:00517072200.017
regenerationGO:00310991630.017
positive regulation of rna metabolic processGO:00512542030.017
leukocyte activationGO:0045321760.017
nucleobase containing small molecule metabolic processGO:00550863160.017
response to growth factorGO:00708481890.017
neuron apoptotic processGO:0051402880.017
response to biotic stimulusGO:00096072260.017
positive regulation of protein modification processGO:00314011420.017
negative regulation of transportGO:00510511360.016
polysaccharide metabolic processGO:0005976250.016
negative regulation of phosphate metabolic processGO:0045936800.016
gonad developmentGO:00084061040.016
negative regulation of protein metabolic processGO:00512481140.016
regulation of anatomical structure morphogenesisGO:00226031410.016
peptidyl amino acid modificationGO:00181931260.016
positive regulation of nucleobase containing compound metabolic processGO:00459353190.016
positive regulation of phosphate metabolic processGO:00459372620.016
apoptotic signaling pathwayGO:0097190270.016
macromolecule localizationGO:00330362520.016
cell morphogenesis involved in neuron differentiationGO:00486671060.016
positive regulation of cell growthGO:0030307440.016
response to nicotineGO:0035094510.016
single organism intracellular transportGO:19025821660.016
intracellular transportGO:00469071850.016
protein transportGO:00150311320.015
axonogenesisGO:0007409710.015
response to acid chemicalGO:00011012220.015
regulation of system processGO:00440572080.015
response to vitaminGO:00332731310.015
cell migrationGO:00164771970.015
cellular homeostasisGO:00197252520.015
spermatogenesisGO:0007283990.015
positive regulation of cell communicationGO:00106472710.015
regulation of phosphate metabolic processGO:00192203490.015
peptidyl tyrosine phosphorylationGO:0018108720.015
single organism behaviorGO:00447081300.015
cellular response to external stimulusGO:00714961180.015
vasculature developmentGO:0001944700.015
central nervous system developmentGO:00074173110.015
positive regulation of rna biosynthetic processGO:19026801970.015
monosaccharide metabolic processGO:0005996610.015
negative regulation of secretionGO:0051048820.015
organic substance catabolic processGO:19015753160.015
Human Yeast
divalent inorganic cation homeostasisGO:00725071650.014
motor neuron axon guidanceGO:000804510.014
positive regulation of phosphorylationGO:00423271770.014
digestive tract developmentGO:0048565390.014
positive regulation of cell differentiationGO:00455972170.014
dna recombinationGO:000631030.014
regulation of hormone levelsGO:00108171870.014
protein maturationGO:0051604680.014
multicellular organism growthGO:003526410.014
regulation of hydrolase activityGO:00513361430.014
localization of cellGO:00516742020.014
regulation of hormone secretionGO:00468831060.014
cellular protein localizationGO:00346131220.014
heterocycle catabolic processGO:00467001670.014
protein complex biogenesisGO:00702712630.014
regulation of membrane potentialGO:00423911100.014
negative regulation of catalytic activityGO:00430861030.014
protein oligomerizationGO:00512591910.014
positive regulation of protein kinase activityGO:0045860730.014
development of primary sexual characteristicsGO:00451371070.014
regulation of protein modification processGO:00313991940.014
cellular response to insulin stimulusGO:0032869810.014
regulation of intracellular signal transductionGO:19025312180.014
negative regulation of mitotic cell cycle phase transitionGO:190199130.013
anatomical structure formation involved in morphogenesisGO:0048646830.013
carboxylic acid catabolic processGO:0046395490.013
cytoskeleton dependent cytokinesisGO:006164020.013
organophosphate catabolic processGO:00464341480.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
negative regulation of signal transductionGO:0009968830.013
cell part morphogenesisGO:00329901230.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
regulation of transcription from rna polymerase ii promoterGO:00063572340.013
positive regulation of protein phosphorylationGO:00019341350.013
response to light stimulusGO:0009416520.013
gastrulationGO:000736920.013
positive regulation of signalingGO:00230562700.013
nucleoside phosphate metabolic processGO:00067532830.013
positive regulation of catalytic activityGO:00430851840.013
cell projection morphogenesisGO:00488581230.013
regulation of peptide transportGO:0090087870.013
mapk cascadeGO:00001651400.013
positive regulation of molecular functionGO:00440932300.013
negative regulation of cellular metabolic processGO:00313242810.013
angiogenesisGO:0001525530.013
carbohydrate catabolic processGO:0016052400.013
hormone transportGO:00099141210.013
hormone secretionGO:00468791150.013
sulfur compound metabolic processGO:0006790700.012
regulation of homeostatic processGO:00328441010.012
regulation of mrna splicing via spliceosomeGO:004802430.012
positive regulation of catabolic processGO:0009896780.012
regulation of protein kinase activityGO:00458591050.012
glycosyl compound catabolic processGO:19016581260.012
nucleobase containing compound catabolic processGO:00346551520.012
cellular response to organic cyclic compoundGO:00714072020.012
carbohydrate derivative catabolic processGO:19011361470.012
nucleoside phosphate catabolic processGO:19012921400.012
positive regulation of growthGO:0045927550.012
cellular polysaccharide metabolic processGO:0044264230.012
positive regulation of lipid catabolic processGO:005099640.012
mrna metabolic processGO:0016071200.012
ribose phosphate metabolic processGO:00196932350.012
positive regulation of cell migrationGO:0030335960.012
negative regulation of molecular functionGO:00440921330.012
negative regulation of neuron deathGO:1901215690.012
proteolysisGO:00065081750.012
Human Yeast Rat
male gamete generationGO:0048232990.012
purine nucleoside catabolic processGO:00061521240.012
dna metabolic processGO:0006259960.012
nucleotide metabolic processGO:00091172790.012
rna localizationGO:000640340.012
negative regulation of macromolecule metabolic processGO:00106052600.012
regulation of circadian rhythmGO:0042752270.012
cell cycleGO:00070491010.011
learning or memoryGO:0007611900.011
macromolecular complex subunit organizationGO:00439333390.011
alpha amino acid biosynthetic processGO:1901607230.011
regulation of cell differentiationGO:00455953200.011
positive regulation of response to stimulusGO:00485842850.011
brain developmentGO:00074202470.011
regulation of protein phosphorylationGO:00019321830.011
neurological system processGO:00508772190.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
regulation of response to stressGO:00801341260.011
protein complex assemblyGO:00064612630.011
rho protein signal transductionGO:0007266110.011
urogenital system developmentGO:0001655780.011
signal transduction by phosphorylationGO:00230141440.011
cellular modified amino acid metabolic processGO:0006575610.011
organic cyclic compound catabolic processGO:19013611750.011
muscle structure developmentGO:0061061870.011
negative regulation of cellular protein metabolic processGO:00322691060.011
protein processingGO:0016485680.011
cellular response to growth factor stimulusGO:00713631620.011
cellular chemical homeostasisGO:00550822470.011
amide transportGO:00428861050.011
carbohydrate biosynthetic processGO:0016051420.011
regulation of nervous system developmentGO:00519602640.011
chemotaxisGO:0006935660.011
regulation of cell projection organizationGO:00313441750.011
dephosphorylationGO:0016311980.011
spindle organizationGO:000705120.011
regulation of anatomical structure sizeGO:00900661350.011
positive regulation of cell motilityGO:2000147970.011
regulation of phosphorus metabolic processGO:00511743490.011
regulation of proteolysisGO:0030162660.011
signal releaseGO:00230611450.011
erythrocyte differentiationGO:003021810.011
purine nucleotide metabolic processGO:00061632290.011
mitotic cell cycle phase transitionGO:0044772200.010
positive regulation of nucleic acid templated transcriptionGO:19035081970.010
response to mechanical stimulusGO:00096121340.010
regulation of neurogenesisGO:00507672470.010
axis specificationGO:000979840.010
regulation of alternative mrna splicing via spliceosomeGO:000038120.010
epithelium developmentGO:0060429960.010
negative regulation of biosynthetic processGO:00098901680.010
erythrocyte homeostasisGO:003410120.010

Lta4h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
musculoskeletal system diseaseDOID:1700.028
connective tissue diseaseDOID:6500.017
bone diseaseDOID:008000100.011
disease of cellular proliferationDOID:1456600.010
nervous system diseaseDOID:86300.010