Rattus norvegicus

0 known processes

Lrrk1

leucine-rich repeat kinase 1

Lrrk1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to hormone stimulusGO:00328702470.090
intracellular signal transductionGO:00355563140.088
protein complex subunit organizationGO:00718223020.065
response to acid chemicalGO:00011012220.062
macromolecular complex subunit organizationGO:00439333390.062
protein phosphorylationGO:00064683450.061
regulation of transcription from rna polymerase ii promoterGO:00063572340.061
organic acid metabolic processGO:00060822920.058
cellular component assemblyGO:00226073600.057
regulation of rna metabolic processGO:00512523910.056
response to peptideGO:19016522920.056
response to ketoneGO:19016541820.054
response to estrogenGO:00436272320.053
cellular component biogenesisGO:00440853680.050
response to inorganic substanceGO:00100353770.050
cellular response to oxygen containing compoundGO:19017013860.048
response to extracellular stimulusGO:00099913800.048
response to metal ionGO:00100382530.046
response to peptide hormoneGO:00434342780.046
regulation of apoptotic processGO:00429813350.046
apoptotic processGO:00069153810.046
carboxylic acid metabolic processGO:00197522890.044
response to oxidative stressGO:00069791860.044
cellular catabolic processGO:00442482950.044
anatomical structure morphogenesisGO:00096532980.044
regulation of multicellular organismal developmentGO:20000263760.043
response to nutrient levelsGO:00316673700.043
catabolic processGO:00090563510.043
oxoacid metabolic processGO:00434362900.042
response to corticosteroidGO:00319602350.042
protein complex biogenesisGO:00702712630.042
central nervous system developmentGO:00074173110.042
cellular response to organic cyclic compoundGO:00714072020.040
cellular response to nitrogen compoundGO:19016992100.040
cellular component movementGO:00069282480.039
programmed cell deathGO:00125013920.039
negative regulation of gene expressionGO:00106291990.038
brain developmentGO:00074202470.038
macromolecular complex assemblyGO:00650032730.038
regulation of programmed cell deathGO:00430673410.038
regulation of phosphate metabolic processGO:00192203490.037
protein oligomerizationGO:00512591910.037
tissue developmentGO:00098882520.037
response to organophosphorusGO:00466831020.036
protein complex assemblyGO:00064612630.035
response to oxygen levelsGO:00704822650.035
cellular response to endogenous stimulusGO:00714953770.034
multi organism reproductive processGO:00447032620.034
single organism reproductive processGO:00447022970.034
negative regulation of metabolic processGO:00098923310.034
rna biosynthetic processGO:00327743800.033
positive regulation of cellular biosynthetic processGO:00313282950.033
reproductionGO:00000032450.033
female gonad developmentGO:0008585530.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
reproductive processGO:00224143720.033
enzyme linked receptor protein signaling pathwayGO:00071671160.032
transcription dna templatedGO:00063513770.032
response to transition metal nanoparticleGO:19902671220.032
response to growth factorGO:00708481890.031
cellular response to stressGO:00335542690.031
response to external biotic stimulusGO:00432072210.031
eye morphogenesisGO:004859240.030
nucleic acid templated transcriptionGO:00976593790.030
rhythmic processGO:00485111560.030
regulation of molecular functionGO:00650093980.030
regulation of cellular localizationGO:00603412630.030
cellular response to organonitrogen compoundGO:00714171970.029
positive regulation of macromolecule biosynthetic processGO:00105572470.029
multicellular organism reproductionGO:00325042330.029
positive regulation of multicellular organismal processGO:00512403870.029
cellular response to lipidGO:00713962010.029
organic substance catabolic processGO:19015753160.029
regulation of cellular ketone metabolic processGO:0010565270.028
regulation of signal transductionGO:00099663180.027
regulation of protein metabolic processGO:00512462890.027
regulation of cell differentiationGO:00455953200.027
regulation of cellular protein metabolic processGO:00322682670.026
regenerationGO:00310991630.026
cellular component morphogenesisGO:00329891550.026
positive regulation of nucleic acid templated transcriptionGO:19035081970.026
positive regulation of rna metabolic processGO:00512542030.025
regulation of rna biosynthetic processGO:20011413810.025
organonitrogen compound catabolic processGO:19015651790.025
cellular amine metabolic processGO:0044106380.025
single organism catabolic processGO:00447122830.025
transmembrane transportGO:00550854120.025
head developmentGO:00603222470.025
response to nutrientGO:00075842480.025
positive regulation of gene expressionGO:00106282440.025
agingGO:00075682410.025
positive regulation of biosynthetic processGO:00098913190.024
positive regulation of rna biosynthetic processGO:19026801970.024
response to alkaloidGO:00432791320.024
regulation of protein modification processGO:00313991940.024
transcription from rna polymerase ii promoterGO:00063662520.024
response to hypoxiaGO:00016662310.024
cellular amino acid metabolic processGO:00065201070.024
response to ethanolGO:00454711620.024
single organism biosynthetic processGO:00447113420.023
development of primary female sexual characteristicsGO:0046545560.023
positive regulation of transportGO:00510502450.023
secretion by cellGO:00329402480.023
response to hydrogen peroxideGO:0042542890.023
lipid metabolic processGO:00066292830.023
positive regulation of cell proliferationGO:00082842490.023
response to glucocorticoidGO:00513842230.023
cellular ketone metabolic processGO:0042180510.023
regulation of cell adhesionGO:0030155520.023
immune system processGO:00023762040.023
rna metabolic processGO:00160704060.023
regulation of secretion by cellGO:19035302080.022
negative regulation of programmed cell deathGO:00430691830.022
regulation of nervous system developmentGO:00519602640.022
regulation of secretionGO:00510462240.022
regulation of cellular component organizationGO:00511283680.022
positive regulation of cell deathGO:00109421840.022
monocarboxylic acid metabolic processGO:00327871520.021
response to reactive oxygen speciesGO:00003021200.021
response to other organismGO:00517072200.021
positive regulation of developmental processGO:00510942830.021
organophosphate metabolic processGO:00196373700.021
response to vitaminGO:00332731310.021
response to insulinGO:00328681330.021
cellular response to steroid hormone stimulusGO:0071383930.021
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
amine metabolic processGO:0009308380.021
secretionGO:00469033070.021
localization of cellGO:00516742020.021
negative regulation of response to stimulusGO:00485851550.020
response to decreased oxygen levelsGO:00362932370.020
negative regulation of cellular metabolic processGO:00313242810.020
positive regulation of cellular protein metabolic processGO:00322701670.020
positive regulation of molecular functionGO:00440932300.020
regulation of cell proliferationGO:00421273590.020
nucleotide metabolic processGO:00091172790.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.020
positive regulation of cell communicationGO:00106472710.020
regulation of cellular amino acid metabolic processGO:000652120.020
cellular response to growth factor stimulusGO:00713631620.020
multicellular organismal reproductive processGO:00486092330.019
negative regulation of multicellular organismal processGO:00512412030.019
cellular response to peptideGO:19016531330.019
positive regulation of transcription dna templatedGO:00458931970.019
nucleobase containing small molecule metabolic processGO:00550863160.019
response to carbohydrateGO:00097431830.019
forebrain developmentGO:0030900980.019
response to cytokineGO:00340972150.019
positive regulation of cellular component organizationGO:00511302000.019
response to woundingGO:00096112540.019
cellular lipid metabolic processGO:00442552080.018
negative regulation of apoptotic processGO:00430661810.018
positive regulation of catalytic activityGO:00430851840.018
regulation of anatomical structure morphogenesisGO:00226031410.018
response to purine containing compoundGO:00140741260.018
regulation of catalytic activityGO:00507903040.018
organ regenerationGO:00311001010.018
negative regulation of cell deathGO:00605482290.018
positive regulation of programmed cell deathGO:00430681570.017
macromolecule localizationGO:00330362520.017
response to bacteriumGO:00096172000.017
regulation of transcription dna templatedGO:00063553740.017
positive regulation of protein metabolic processGO:00512471780.017
protein localizationGO:00081041910.017
positive regulation of cell differentiationGO:00455972170.017
regulation of neurogenesisGO:00507672470.017
cellular response to acid chemicalGO:0071229750.017
nitrogen compound transportGO:00717052290.017
regulation of phosphorylationGO:00423252480.017
regulation of cellular amine metabolic processGO:003323880.017
cell adhesionGO:00071551100.017
negative regulation of signalingGO:00230571570.017
neurological system processGO:00508772190.017
regulation of protein phosphorylationGO:00019321830.017
positive regulation of nucleobase containing compound metabolic processGO:00459353190.017
ras protein signal transductionGO:0007265290.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
carbohydrate derivative metabolic processGO:19011353460.016
negative regulation of cell communicationGO:00106481580.016
gamete generationGO:00072761240.016
vesicle mediated transportGO:00161921810.016
oxidation reduction processGO:00551143040.016
proteolysisGO:00065081750.016
response to radiationGO:00093141370.016
negative regulation of macromolecule metabolic processGO:00106052600.015
reproductive structure developmentGO:00486081280.015
cellular response to peptide hormone stimulusGO:00713751200.015
gastrulationGO:000736920.015
sex differentiationGO:00075481130.015
axis specificationGO:000979840.015
response to monosaccharideGO:00342841590.015
organic anion transportGO:00157111320.015
developmental process involved in reproductionGO:00030061590.015
epithelium developmentGO:0060429960.015
growthGO:00400071650.015
cardiovascular system developmentGO:00723581340.015
action potentialGO:0001508540.015
gland developmentGO:00487321550.015
reproductive system developmentGO:00614581280.015
ossificationGO:0001503700.015
regulation of nucleic acid templated transcriptionGO:19035063800.015
protein heterooligomerizationGO:0051291890.015
biological adhesionGO:00226101100.015
negative regulation of cellular biosynthetic processGO:00313271610.015
dna metabolic processGO:0006259960.015
small gtpase mediated signal transductionGO:0007264360.015
wound healingGO:00420601220.015
anterior posterior pattern specificationGO:000995210.015
organ morphogenesisGO:0009887750.015
cellular homeostasisGO:00197252520.015
ribose phosphate metabolic processGO:00196932350.015
skeletal system developmentGO:0001501410.015
nucleoside phosphate metabolic processGO:00067532830.015
chemical homeostasisGO:00488782920.014
ovulation cycleGO:0042698670.014
positive regulation of response to stimulusGO:00485842850.014
protein transportGO:00150311320.014
neuron developmentGO:00486662860.014
ribonucleotide metabolic processGO:00092592310.014
organelle organizationGO:00069962660.014
establishment of protein localizationGO:00451841410.014
regulation of embryonic developmentGO:004599520.014
response to amino acidGO:0043200750.014
metal ion homeostasisGO:00550651860.014
regulation of cell developmentGO:00602842630.014
cation homeostasisGO:00550801950.014
positive regulation of cellular amine metabolic processGO:003324030.014
single organism organelle organizationGO:19025891800.014
female sex differentiationGO:0046660590.014
regulation of hormone levelsGO:00108171870.014
sexual reproductionGO:00199531480.014
response to toxic substanceGO:00096361330.014
regulation of immune system processGO:00026821230.014
neuron projection developmentGO:00311752730.014
neuron differentiationGO:00301823680.014
regulation of neuron projection developmentGO:00109751610.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.013
response to molecule of bacterial originGO:00022371940.013
cellular cation homeostasisGO:00300031800.013
liver developmentGO:0001889900.013
regulation of response to stressGO:00801341260.013
vasculogenesisGO:000157030.013
regulation of cell migrationGO:00303341280.013
positive regulation of apoptotic processGO:00430651540.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
single organism intracellular transportGO:19025821660.013
response to retinoic acidGO:0032526630.013
cell morphogenesisGO:00009021420.013
urogenital system developmentGO:0001655780.013
negative regulation of cell differentiationGO:0045596990.013
cell motilityGO:00488702020.013
ion homeostasisGO:00508012120.013
digestive system developmentGO:0055123410.013
homeostatic processGO:00425923310.013
positive regulation of immune system processGO:0002684900.013
response to lipopolysaccharideGO:00324961910.013
regulation of transferase activityGO:00513381230.012
limbic system developmentGO:0021761380.012
cellular chemical homeostasisGO:00550822470.012
regulation of bmp signaling pathwayGO:003051020.012
salivary gland developmentGO:000743130.012
telencephalon developmentGO:0021537620.012
response to estradiolGO:00323551640.012
g protein coupled receptor signaling pathwayGO:00071862420.012
inorganic ion transmembrane transportGO:00986602290.012
digestive tract developmentGO:0048565390.012
positive regulation of nervous system developmentGO:00519621780.012
embryonic skeletal system developmentGO:004870630.012
circulatory system developmentGO:00723591340.012
tube developmentGO:0035295890.012
positive regulation of lipid kinase activityGO:009021820.012
regulation of phosphorus metabolic processGO:00511743490.012
cell cell signalingGO:00072673350.012
spermatogenesisGO:0007283990.012
positive regulation of phosphate metabolic processGO:00459372620.012
response to hyperoxiaGO:0055093450.012
defense response to gram negative bacteriumGO:005082930.012
response to biotic stimulusGO:00096072260.012
cation transportGO:00068123820.012
fatty acid metabolic processGO:0006631990.012
cellular ion homeostasisGO:00068731840.012
negative regulation of molecular functionGO:00440921330.012
carbohydrate metabolic processGO:00059751300.012
learning or memoryGO:0007611900.012
regulation of growthGO:00400081050.012
behaviorGO:00076102050.012
positive regulation of protein modification processGO:00314011420.012
female pregnancyGO:00075651220.012
regulation of cellular component movementGO:00512701500.011
regulation of dna metabolic processGO:0051052600.011
embryonic pattern specificationGO:000988010.011
positive regulation of secretionGO:00510471400.011
regulation of intracellular signal transductionGO:19025312180.011
negative regulation of developmental processGO:00510931250.011
cytoplasmic transportGO:00164821150.011
cell growthGO:00160491040.011
gonad developmentGO:00084061040.011
male gamete generationGO:0048232990.011
response to campGO:0051591910.011
negative regulation of signal transductionGO:0009968830.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
response to testosteroneGO:0033574550.011
kidney developmentGO:0001822670.011
rho protein signal transductionGO:0007266110.011
regulation of stem cell differentiationGO:200073620.011
regulation of body fluid levelsGO:0050878900.011
lipid localizationGO:0010876620.011
cell morphogenesis involved in differentiationGO:00009041190.011
negative regulation of transportGO:00510511360.011
peptidyl tyrosine modificationGO:0018212720.011
response to nicotineGO:0035094510.011
nucleobase containing compound catabolic processGO:00346551520.011
formation of primary germ layerGO:000170410.011
cellular nitrogen compound catabolic processGO:00442701630.011
positive regulation of secretion by cellGO:19035321280.011
anion transportGO:00068201780.011
positive regulation of signal transductionGO:00099671750.011
regulation of hydrolase activityGO:00513361430.011
limb morphogenesisGO:003510840.011
organic hydroxy compound transportGO:0015850770.011
positive regulation of phosphorus metabolic processGO:00105622620.010
cellular response to abiotic stimulusGO:0071214850.010
cellular divalent inorganic cation homeostasisGO:00725031620.010
cellular calcium ion homeostasisGO:00068741600.010
b cell differentiationGO:003018320.010
heart developmentGO:0007507720.010
regulation of membrane potentialGO:00423911100.010
camera type eye morphogenesisGO:004859320.010
regulation of protein localizationGO:0032880810.010
response to fatty acidGO:0070542650.010
ion transmembrane transportGO:00342203650.010
negative regulation of macromolecule biosynthetic processGO:00105581480.010
positive regulation of signalingGO:00230562700.010
response to glucoseGO:00097491360.010
organonitrogen compound biosynthetic processGO:19015661670.010
embryonic axis specificationGO:000057810.010

Lrrk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.025
disease of anatomical entityDOID:700.025
connective tissue diseaseDOID:6500.014
nervous system diseaseDOID:86300.014
disease of metabolismDOID:001466700.013
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
myopathyDOID:42300.011
central nervous system diseaseDOID:33100.010