Rattus norvegicus

10 known processes

Lrrk2

leucine-rich repeat kinase 2

Lrrk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carbohydrate derivative metabolic processGO:19011353460.068
nucleobase containing small molecule metabolic processGO:00550863160.058
nucleoside phosphate metabolic processGO:00067532830.055
aromatic compound catabolic processGO:00194391680.053
single organism catabolic processGO:00447122830.052
purine containing compound metabolic processGO:00725212530.050
nucleotide metabolic processGO:00091172790.048
organic acid metabolic processGO:00060822920.048
purine ribonucleotide metabolic processGO:00091502270.047
organophosphate metabolic processGO:00196373700.047
cellular component biogenesisGO:00440853680.047
purine nucleotide metabolic processGO:00061632290.047
ribonucleotide metabolic processGO:00092592310.046
organic substance catabolic processGO:19015753160.046
oxoacid metabolic processGO:00434362900.044
carboxylic acid metabolic processGO:00197522890.043
nucleoside triphosphate metabolic processGO:00091411440.043
catabolic processGO:00090563510.042
protein phosphorylationGO:00064683450.041
nucleoside metabolic processGO:00091161790.041
organic cyclic compound catabolic processGO:19013611750.040
cellular catabolic processGO:00442482950.040
regulation of cellular component organizationGO:00511283680.039
locomotionGO:00400112370.039
purine ribonucleotide catabolic processGO:00091541360.038
organophosphate catabolic processGO:00464341480.038
intracellular signal transductionGO:00355563140.038
purine nucleotide catabolic processGO:00061951360.037
purine nucleoside triphosphate metabolic processGO:00091441410.037
cellular amino acid metabolic processGO:00065201070.037
ribonucleotide catabolic processGO:00092611360.037
ribonucleoside triphosphate metabolic processGO:00091991410.037
purine ribonucleoside catabolic processGO:00461301240.037
purine nucleoside triphosphate catabolic processGO:00091461220.036
purine nucleoside metabolic processGO:00422781690.036
ribose phosphate metabolic processGO:00196932350.036
cellular component assemblyGO:00226073600.036
carbohydrate derivative catabolic processGO:19011361470.036
cellular ketone metabolic processGO:0042180510.035
ribonucleoside catabolic processGO:00424541260.035
regulation of phosphate metabolic processGO:00192203490.035
nucleotide catabolic processGO:00091661390.034
regulation of phosphorus metabolic processGO:00511743490.034
cellular component movementGO:00069282480.033
ribonucleoside triphosphate catabolic processGO:00092031220.033
regulation of cellular ketone metabolic processGO:0010565270.033
nucleoside phosphate catabolic processGO:19012921400.033
amine metabolic processGO:0009308380.033
heterocycle catabolic processGO:00467001670.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
nucleoside triphosphate catabolic processGO:00091431230.033
regulation of cellular amino acid metabolic processGO:000652120.032
positive regulation of phosphorus metabolic processGO:00105622620.032
homeostatic processGO:00425923310.032
purine ribonucleoside triphosphate metabolic processGO:00092051400.032
regulation of cellular amine metabolic processGO:003323880.032
cellular amine metabolic processGO:0044106380.031
nucleoside catabolic processGO:00091641260.031
regulation of locomotionGO:00400121480.031
purine containing compound catabolic processGO:00725231380.031
regulation of cell differentiationGO:00455953200.031
cellular nitrogen compound catabolic processGO:00442701630.031
organonitrogen compound catabolic processGO:19015651790.030
purine nucleoside catabolic processGO:00061521240.030
purine ribonucleoside triphosphate catabolic processGO:00092071220.030
macromolecular complex subunit organizationGO:00439333390.030
glycosyl compound catabolic processGO:19016581260.029
regulation of multicellular organismal developmentGO:20000263760.029
protein complex assemblyGO:00064612630.029
nucleobase containing compound catabolic processGO:00346551520.029
immune system processGO:00023762040.029
macromolecular complex assemblyGO:00650032730.028
ribonucleoside metabolic processGO:00091191740.028
protein complex biogenesisGO:00702712630.028
regulation of molecular functionGO:00650093980.027
positive regulation of phosphate metabolic processGO:00459372620.027
regulation of signal transductionGO:00099663180.027
vesicle mediated transportGO:00161921810.027
regulation of apoptotic processGO:00429813350.027
cell migrationGO:00164771970.026
organelle organizationGO:00069962660.026
programmed cell deathGO:00125013920.026
chemical homeostasisGO:00488782920.026
rna metabolic processGO:00160704060.025
purine ribonucleoside metabolic processGO:00461281680.025
localization of cellGO:00516742020.025
neuron projection developmentGO:00311752730.025
positive regulation of developmental processGO:00510942830.025
regulation of programmed cell deathGO:00430673410.025
regulation of cell developmentGO:00602842630.025
guanosine containing compound catabolic processGO:1901069710.025
cellular response to oxygen containing compoundGO:19017013860.025
regulation of phosphorylationGO:00423252480.025
positive regulation of cellular amino acid metabolic processGO:004576410.025
positive regulation of cellular amine metabolic processGO:003324030.024
single organism biosynthetic processGO:00447113420.024
cell cell signalingGO:00072673350.024
neuron differentiationGO:00301823680.024
negative regulation of metabolic processGO:00098923310.024
small gtpase mediated signal transductionGO:0007264360.024
regulation of intracellular signal transductionGO:19025312180.024
glycosyl compound metabolic processGO:19016571820.024
response to nutrient levelsGO:00316673700.024
positive regulation of phosphorylationGO:00423271770.024
macromolecule localizationGO:00330362520.024
positive regulation of nucleobase containing compound metabolic processGO:00459353190.023
regulation of neurogenesisGO:00507672470.023
regulation of nervous system developmentGO:00519602640.023
ras protein signal transductionGO:0007265290.023
nucleic acid templated transcriptionGO:00976593790.023
gtp metabolic processGO:0046039720.023
regulation of nucleic acid templated transcriptionGO:19035063800.023
positive regulation of response to stimulusGO:00485842850.023
regulation of cell proliferationGO:00421273590.022
protein complex subunit organizationGO:00718223020.022
response to inorganic substanceGO:00100353770.022
guanosine containing compound metabolic processGO:1901068740.022
cell motilityGO:00488702020.022
response to extracellular stimulusGO:00099913800.022
positive regulation of multicellular organismal processGO:00512403870.022
positive regulation of cell proliferationGO:00082842490.022
protein localizationGO:00081041910.022
synaptic transmissionGO:00072682350.022
protein oligomerizationGO:00512591910.021
positive regulation of cell developmentGO:00107201760.021
positive regulation of nervous system developmentGO:00519621780.021
reproductive processGO:00224143720.021
rna biosynthetic processGO:00327743800.021
regulation of catalytic activityGO:00507903040.021
gtp catabolic processGO:0006184710.021
regulation of rna metabolic processGO:00512523910.021
regulation of rna biosynthetic processGO:20011413810.021
cell projection organizationGO:00300303020.020
regulation of transcription dna templatedGO:00063553740.020
positive regulation of cellular biosynthetic processGO:00313282950.020
lipid metabolic processGO:00066292830.020
positive regulation of cell communicationGO:00106472710.020
single organism reproductive processGO:00447022970.020
apoptotic processGO:00069153810.020
positive regulation of biosynthetic processGO:00098913190.020
positive regulation of cell migrationGO:0030335960.020
transmembrane transportGO:00550854120.020
negative regulation of multicellular organismal processGO:00512412030.020
regulation of protein modification processGO:00313991940.020
ion transmembrane transportGO:00342203650.020
ion homeostasisGO:00508012120.020
positive regulation of neurogenesisGO:00507691650.019
cellular homeostasisGO:00197252520.019
regulation of neuron differentiationGO:00456642080.019
regulation of protein metabolic processGO:00512462890.019
positive regulation of cell differentiationGO:00455972170.019
regulation of cell motilityGO:20001451310.019
secretionGO:00469033070.019
anatomical structure morphogenesisGO:00096532980.019
single organism intracellular transportGO:19025821660.019
regulation of protein phosphorylationGO:00019321830.019
multi organism reproductive processGO:00447032620.019
regulation of cellular protein metabolic processGO:00322682670.019
intracellular transportGO:00469071850.019
neuron developmentGO:00486662860.018
cation transportGO:00068123820.018
negative regulation of innate immune responseGO:004582440.018
negative regulation of cellular metabolic processGO:00313242810.018
neurological system processGO:00508772190.018
behaviorGO:00076102050.018
regulation of cell projection organizationGO:00313441750.018
cellular chemical homeostasisGO:00550822470.018
cellular response to endogenous stimulusGO:00714953770.018
positive regulation of protein modification processGO:00314011420.018
multicellular organism reproductionGO:00325042330.018
positive regulation of molecular functionGO:00440932300.018
transcription dna templatedGO:00063513770.018
positive regulation of cellular component organizationGO:00511302000.018
central nervous system developmentGO:00074173110.017
oxidation reduction processGO:00551143040.017
response to acid chemicalGO:00011012220.017
anterior posterior pattern specificationGO:000995210.017
nitrogen compound transportGO:00717052290.017
regulation of cellular component movementGO:00512701500.017
positive regulation of protein phosphorylationGO:00019341350.017
negative regulation of macromolecule metabolic processGO:00106052600.017
metal ion transportGO:00300012890.017
response to oxidative stressGO:00069791860.017
cellular lipid metabolic processGO:00442552080.017
multicellular organismal reproductive processGO:00486092330.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
regulation of neuron projection developmentGO:00109751610.017
regulation of nucleotide metabolic processGO:00061401170.017
positive regulation of protein metabolic processGO:00512471780.016
muscle system processGO:00030121150.016
response to growth factorGO:00708481890.016
establishment of protein localizationGO:00451841410.016
reproductionGO:00000032450.016
positive regulation of gene expressionGO:00106282440.016
head developmentGO:00603222470.016
positive regulation of rna metabolic processGO:00512542030.016
response to peptideGO:19016522920.016
inorganic ion transmembrane transportGO:00986602290.016
regulation of cellular localizationGO:00603412630.016
negative regulation of signalingGO:00230571570.016
synaptic growth at neuromuscular junctionGO:005112410.016
positive regulation of signalingGO:00230562700.016
response to molecule of bacterial originGO:00022371940.016
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.016
positive regulation of locomotionGO:00400171020.016
cellular response to stressGO:00335542690.016
response to decreased oxygen levelsGO:00362932370.016
blood circulationGO:00080151830.016
smooth muscle cell proliferationGO:0048659770.016
tissue developmentGO:00098882520.016
positive regulation of cell motilityGO:2000147970.016
response to peptide hormoneGO:00434342780.016
response to ethanolGO:00454711620.016
circulatory system developmentGO:00723591340.016
cellular protein localizationGO:00346131220.016
regulation of system processGO:00440572080.016
positive regulation of cellular component movementGO:00512721020.016
positive regulation of intracellular signal transductionGO:19025331380.015
cellular macromolecule localizationGO:00707271220.015
antigen processing and presentationGO:001988220.015
regulation of kinase activityGO:00435491170.015
regulation of synaptic transmissionGO:00508041410.015
positive regulation of cellular protein metabolic processGO:00322701670.015
cardiovascular system developmentGO:00723581340.015
positive regulation of catalytic activityGO:00430851840.015
response to metal ionGO:00100382530.015
positive regulation of signal transductionGO:00099671750.015
response to external biotic stimulusGO:00432072210.015
regulation of vesicle mediated transportGO:0060627810.015
response to nutrientGO:00075842480.015
cation homeostasisGO:00550801950.015
negative regulation of natural killer cell mediated immunityGO:000271640.015
regulation of membrane potentialGO:00423911100.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
circulatory system processGO:00030131830.015
negative regulation of cell communicationGO:00106481580.015
axis specificationGO:000979840.014
response to oxygen levelsGO:00704822650.014
regulation of purine nucleotide metabolic processGO:19005421150.014
negative regulation of response to stimulusGO:00485851550.014
response to biotic stimulusGO:00096072260.014
positive regulation of neuron differentiationGO:00456661260.014
transcription from rna polymerase ii promoterGO:00063662520.014
response to ketoneGO:19016541820.014
metal ion homeostasisGO:00550651860.014
cellular response to nitrogen compoundGO:19016992100.014
cellular response to organonitrogen compoundGO:00714171970.014
peptidyl amino acid modificationGO:00181931260.014
response to hypoxiaGO:00016662310.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
regulation of mapk cascadeGO:00434081160.014
divalent inorganic cation homeostasisGO:00725071650.014
carbohydrate derivative biosynthetic processGO:19011371240.014
negative regulation of cell deathGO:00605482290.013
brain developmentGO:00074202470.013
regenerationGO:00310991630.013
regulation of transferase activityGO:00513381230.013
regulation of hormone levelsGO:00108171870.013
response to bacteriumGO:00096172000.013
cytoplasmic transportGO:00164821150.013
positive regulation of transportGO:00510502450.013
signal transduction by phosphorylationGO:00230141440.013
negative regulation of developmental processGO:00510931250.013
regulation of secretion by cellGO:19035302080.013
single organism carbohydrate metabolic processGO:00447231180.013
calcium ion homeostasisGO:00550741620.013
cellular response to hormone stimulusGO:00328702470.013
anion transportGO:00068201780.013
regulation of catabolic processGO:00098941130.013
endocytosisGO:0006897840.013
embryonic pattern specificationGO:000988010.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
regulation of smooth muscle cell proliferationGO:0048660750.013
muscle cell proliferationGO:0033002840.013
response to woundingGO:00096112540.013
protein transportGO:00150311320.013
response to carbohydrateGO:00097431830.013
response to glucocorticoidGO:00513842230.013
positive regulation of macromolecule biosynthetic processGO:00105572470.013
mapk cascadeGO:00001651400.013
cellular response to lipidGO:00713962010.013
cellular component morphogenesisGO:00329891550.013
golgi vesicle transportGO:0048193220.013
salivary gland developmentGO:000743130.012
agingGO:00075682410.012
single organism cellular localizationGO:19025801020.012
positive regulation of cell projection organizationGO:00313461110.012
cellular cation homeostasisGO:00300031800.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
reactive oxygen species metabolic processGO:0072593370.012
response to hexoseGO:00097461440.012
positive regulation of neuron projection developmentGO:0010976990.012
cellular response to growth factor stimulusGO:00713631620.012
positive regulation of cell deathGO:00109421840.012
chromosome segregationGO:000705920.012
carbohydrate metabolic processGO:00059751300.012
intracellular protein transportGO:0006886790.012
g protein coupled receptor signaling pathwayGO:00071862420.012
regulation of protein kinase activityGO:00458591050.012
regulation of homeostatic processGO:00328441010.012
response to glucoseGO:00097491360.012
positive regulation of apoptotic processGO:00430651540.012
spindle organizationGO:000705120.012
cellular ion homeostasisGO:00068731840.012
negative regulation of programmed cell deathGO:00430691830.012
vascular process in circulatory systemGO:0003018960.012
growthGO:00400071650.012
defense responseGO:00069521940.012
cation transmembrane transportGO:00986552630.012
cell projection morphogenesisGO:00488581230.012
lipid storageGO:001991510.012
positive regulation of smooth muscle cell proliferationGO:0048661510.012
cell morphogenesisGO:00009021420.012
divalent inorganic cation transportGO:00725111340.012
cellular calcium ion homeostasisGO:00068741600.012
response to corticosteroidGO:00319602350.012
regulation of anatomical structure sizeGO:00900661350.012
regulation of cell migrationGO:00303341280.012
positive regulation of nucleotide metabolic processGO:0045981910.012
negative regulation of apoptotic processGO:00430661810.012
regulation of immune system processGO:00026821230.012
positive regulation of mapk cascadeGO:0043410920.012
chemosensory behaviorGO:000763520.012
regulation of hydrolase activityGO:00513361430.012
regulation of neuron deathGO:19012141150.011
peptide transportGO:0015833970.011
inflammatory responseGO:00069541500.011
monovalent inorganic cation transportGO:00156721720.011
sexual reproductionGO:00199531480.011
response to lipopolysaccharideGO:00324961910.011
monocarboxylic acid metabolic processGO:00327871520.011
immune responseGO:00069551040.011
secretion by cellGO:00329402480.011
reactive oxygen species biosynthetic processGO:190340980.011
rho protein signal transductionGO:0007266110.011
single organism behaviorGO:00447081300.011
inorganic cation transmembrane transportGO:00986622020.011
neuron deathGO:00709971270.011
membrane organizationGO:0061024940.011
regulation of secretionGO:00510462240.011
signal releaseGO:00230611450.011
eye morphogenesisGO:004859240.011
positive regulation of rna biosynthetic processGO:19026801970.011
regulation of synaptic plasticityGO:0048167700.011
single organism organelle organizationGO:19025891800.011
response to cytokineGO:00340972150.011
developmental process involved in reproductionGO:00030061590.011
response to monosaccharideGO:00342841590.011
female pregnancyGO:00075651220.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
hormone transportGO:00099141210.011
regulation of ion transportGO:00432692450.011
amide transportGO:00428861050.011
dephosphorylationGO:0016311980.011
leukocyte cell cell adhesionGO:000715940.011
rhythmic processGO:00485111560.011
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.011
multi multicellular organism processGO:00447061380.011
mitotic spindle organizationGO:000705220.011
maintenance of locationGO:0051235170.011
reactive nitrogen species metabolic processGO:200105710.011
negative regulation of gene expressionGO:00106291990.011
regulation of response to stressGO:00801341260.011
actin filament based processGO:0030029860.011
negative regulation of cellular biosynthetic processGO:00313271610.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
organonitrogen compound biosynthetic processGO:19015661670.011
gastrulationGO:000736920.011
organophosphate biosynthetic processGO:00904071430.011
organic anion transportGO:00157111320.011
peptidyl tyrosine phosphorylationGO:0018108720.011
negative regulation of cellular protein metabolic processGO:00322691060.011
cytokine biosynthetic processGO:004208930.011
smooth muscle cell migrationGO:0014909360.011
gland developmentGO:00487321550.011
development of primary sexual characteristicsGO:00451371070.011
regulation of anatomical structure morphogenesisGO:00226031410.010
action potentialGO:0001508540.010
negative regulation of biosynthetic processGO:00098901680.010
sequestering of metal ionGO:005123890.010
sequestering of calcium ionGO:005120880.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
negative regulation of secretionGO:0051048820.010
regulation of reactive oxygen species metabolic processGO:2000377260.010
cellular macromolecular complex assemblyGO:0034622580.010
olfactory learningGO:000835510.010
hormone secretionGO:00468791150.010
response to vitaminGO:00332731310.010
response to radiationGO:00093141370.010
sex differentiationGO:00075481130.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
cell adhesionGO:00071551100.010
rna localizationGO:000640340.010
positive regulation of immune system processGO:0002684900.010
regulation of purine nucleotide catabolic processGO:0033121650.010
cell morphogenesis involved in differentiationGO:00009041190.010
response to estrogenGO:00436272320.010
cellular metal ion homeostasisGO:00068751720.010

Lrrk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.027
disease of anatomical entityDOID:700.027
musculoskeletal system diseaseDOID:1700.015
cardiovascular system diseaseDOID:128700.014
central nervous system diseaseDOID:33100.013
sensory system diseaseDOID:005015500.013
disease of metabolismDOID:001466700.012