Rattus norvegicus

21 known processes

Rb1

retinoblastoma 1

Rb1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.201
positive regulation of macromolecule biosynthetic processGO:00105572470.178
negative regulation of cellular metabolic processGO:00313242810.170
Human
cellular response to endogenous stimulusGO:00714953770.160
negative regulation of biosynthetic processGO:00098901680.148
Human
intracellular signal transductionGO:00355563140.136
Human
regulation of protein metabolic processGO:00512462890.131
Human
positive regulation of multicellular organismal processGO:00512403870.131
regulation of transcription from rna polymerase ii promoterGO:00063572340.119
oxoacid metabolic processGO:00434362900.113
organophosphate metabolic processGO:00196373700.107
negative regulation of nitrogen compound metabolic processGO:00511721610.099
Human
nucleic acid templated transcriptionGO:00976593790.097
Human
negative regulation of macromolecule metabolic processGO:00106052600.097
Human
cell cell signalingGO:00072673350.094
response to oxygen levelsGO:00704822650.091
regulation of nucleic acid templated transcriptionGO:19035063800.090
Human
transcription from rna polymerase ii promoterGO:00063662520.089
rna biosynthetic processGO:00327743800.089
Human
transcription dna templatedGO:00063513770.088
Human
positive regulation of developmental processGO:00510942830.087
regulation of rna biosynthetic processGO:20011413810.085
Human
positive regulation of nitrogen compound metabolic processGO:00511733340.084
positive regulation of nucleobase containing compound metabolic processGO:00459353190.082
central nervous system developmentGO:00074173110.081
immune system processGO:00023762040.077
cellular response to stressGO:00335542690.076
positive regulation of biosynthetic processGO:00098913190.076
regulation of cell proliferationGO:00421273590.075
positive regulation of cellular biosynthetic processGO:00313282950.075
regulation of cellular localizationGO:00603412630.074
Human
organic acid metabolic processGO:00060822920.074
cellular amino acid metabolic processGO:00065201070.073
regulation of catalytic activityGO:00507903040.073
Human
cation transmembrane transportGO:00986552630.072
regulation of cell differentiationGO:00455953200.071
rna metabolic processGO:00160704060.071
Human
cellular response to hormone stimulusGO:00328702470.070
cellular ketone metabolic processGO:0042180510.069
cellular homeostasisGO:00197252520.068
positive regulation of protein metabolic processGO:00512471780.064
Human
negative regulation of metabolic processGO:00098923310.064
Human
nucleobase containing small molecule metabolic processGO:00550863160.061
neuron differentiationGO:00301823680.061
cell cycleGO:00070491010.060
Human
homeostatic processGO:00425923310.057
dendrite developmentGO:0016358720.056
positive regulation of cell differentiationGO:00455972170.055
response to decreased oxygen levelsGO:00362932370.055
regulation of nervous system developmentGO:00519602640.055
regulation of cell developmentGO:00602842630.054
single organism catabolic processGO:00447122830.054
Human
protein complex subunit organizationGO:00718223020.054
positive regulation of apoptotic processGO:00430651540.053
neuron projection developmentGO:00311752730.053
regulation of cellular catabolic processGO:00313291010.053
Human
regulation of molecular functionGO:00650093980.053
Human
apoptotic processGO:00069153810.052
inorganic cation transmembrane transportGO:00986622020.052
chemical homeostasisGO:00488782920.050
positive regulation of gene expressionGO:00106282440.050
regulation of cellular ketone metabolic processGO:0010565270.050
response to peptideGO:19016522920.050
negative regulation of transcription dna templatedGO:00458921160.050
Human
anatomical structure morphogenesisGO:00096532980.048
regulation of phosphorus metabolic processGO:00511743490.048
Human
regulation of apoptotic processGO:00429813350.048
tissue developmentGO:00098882520.047
single organism biosynthetic processGO:00447113420.047
cellular response to lipidGO:00713962010.047
neuron developmentGO:00486662860.047
cell projection organizationGO:00300303020.047
amine metabolic processGO:0009308380.047
response to peptide hormoneGO:00434342780.046
regulation of catabolic processGO:00098941130.046
Human
negative regulation of rna metabolic processGO:00512531230.046
Human
locomotionGO:00400112370.045
positive regulation of cell proliferationGO:00082842490.045
positive regulation of nucleic acid templated transcriptionGO:19035081970.045
cell cycle checkpointGO:000007520.045
organelle organizationGO:00069962660.045
Human
catabolic processGO:00090563510.044
Human
regulation of transcription dna templatedGO:00063553740.044
Human
cellular lipid metabolic processGO:00442552080.043
Human
regulation of multicellular organismal developmentGO:20000263760.043
neurological system processGO:00508772190.043
regulation of cellular amine metabolic processGO:003323880.043
positive regulation of rna biosynthetic processGO:19026801970.042
positive regulation of transcription dna templatedGO:00458931970.042
response to acid chemicalGO:00011012220.042
regulation of cellular component organizationGO:00511283680.042
Human
cellular response to oxygen containing compoundGO:19017013860.041
cell morphogenesisGO:00009021420.041
macromolecular complex subunit organizationGO:00439333390.041
regulation of cellular amino acid metabolic processGO:000652120.041
brain developmentGO:00074202470.040
negative regulation of macromolecule biosynthetic processGO:00105581480.040
Human
protein complex assemblyGO:00064612630.040
regulation of programmed cell deathGO:00430673410.039
organic substance catabolic processGO:19015753160.039
Human
cation transportGO:00068123820.039
regulation of rna metabolic processGO:00512523910.038
Human
negative regulation of cellular biosynthetic processGO:00313271610.038
Human
negative regulation of nucleobase containing compound metabolic processGO:00459341530.038
Human
cellular amine metabolic processGO:0044106380.038
programmed cell deathGO:00125013920.038
ion transmembrane transportGO:00342203650.038
response to hypoxiaGO:00016662310.037
cell projection morphogenesisGO:00488581230.037
secretionGO:00469033070.037
cell part morphogenesisGO:00329901230.036
regulation of intracellular signal transductionGO:19025312180.036
vesicle mediated transportGO:00161921810.036
regulation of signal transductionGO:00099663180.035
ion homeostasisGO:00508012120.035
reproductive processGO:00224143720.035
ribonucleotide metabolic processGO:00092592310.034
regulation of protein modification processGO:00313991940.034
Human
cellular chemical homeostasisGO:00550822470.034
regulation of neurogenesisGO:00507672470.033
purine containing compound metabolic processGO:00725212530.033
response to toxic substanceGO:00096361330.033
single organism organelle organizationGO:19025891800.033
Human
regulation of phosphate metabolic processGO:00192203490.033
Human
positive regulation of rna metabolic processGO:00512542030.032
behaviorGO:00076102050.032
multi organism reproductive processGO:00447032620.032
single organism intracellular transportGO:19025821660.032
cell migrationGO:00164771970.032
cellular component biogenesisGO:00440853680.032
sexual reproductionGO:00199531480.032
protein phosphorylationGO:00064683450.032
Human
response to metal ionGO:00100382530.032
cellular component movementGO:00069282480.031
reproductionGO:00000032450.031
rhythmic processGO:00485111560.031
regulation of cell projection organizationGO:00313441750.031
membrane organizationGO:0061024940.031
intracellular transportGO:00469071850.031
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.030
Human
regulation of cellular protein metabolic processGO:00322682670.030
Human
eye morphogenesisGO:004859240.030
positive regulation of molecular functionGO:00440932300.030
anterior posterior pattern specificationGO:000995210.030
cellular component assemblyGO:00226073600.030
regulation of phosphorylationGO:00423252480.029
Human
cellular catabolic processGO:00442482950.029
Human
nitrogen compound transportGO:00717052290.029
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.029
cellular response to organonitrogen compoundGO:00714171970.029
negative regulation of cell deathGO:00605482290.029
secretion by cellGO:00329402480.028
head developmentGO:00603222470.028
regulation of system processGO:00440572080.028
response to inorganic substanceGO:00100353770.028
single organism reproductive processGO:00447022970.028
purine nucleotide metabolic processGO:00061632290.028
biological adhesionGO:00226101100.028
response to fatty acidGO:0070542650.028
synaptic transmissionGO:00072682350.027
regulation of cell morphogenesisGO:0022604770.027
positive regulation of transportGO:00510502450.027
negative regulation of gene expressionGO:00106291990.027
Human
positive regulation of signal transductionGO:00099671750.027
regulation of protein phosphorylationGO:00019321830.027
Human
cellular carbohydrate metabolic processGO:0044262720.027
developmental process involved in reproductionGO:00030061590.027
response to nutrient levelsGO:00316673700.027
developmental growthGO:00485891000.027
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.027
negative regulation of rna biosynthetic processGO:19026791180.027
Human
multicellular organismal reproductive processGO:00486092330.026
single organism cellular localizationGO:19025801020.026
Human
regulation of locomotionGO:00400121480.026
response to external biotic stimulusGO:00432072210.026
positive regulation of cell deathGO:00109421840.026
metal ion homeostasisGO:00550651860.025
negative regulation of response to stimulusGO:00485851550.025
glycosyl compound metabolic processGO:19016571820.025
ribose phosphate metabolic processGO:00196932350.025
negative regulation of cell communicationGO:00106481580.025
positive regulation of programmed cell deathGO:00430681570.025
positive regulation of phosphate metabolic processGO:00459372620.025
regulation of cell cycleGO:0051726730.025
Human
lipid metabolic processGO:00066292830.025
Human
multicellular organism reproductionGO:00325042330.025
response to monosaccharideGO:00342841590.025
nucleotide metabolic processGO:00091172790.025
response to biotic stimulusGO:00096072260.024
purine ribonucleotide metabolic processGO:00091502270.024
negative regulation of transportGO:00510511360.024
cytoskeleton organizationGO:00070101110.024
Human
transmembrane transportGO:00550854120.024
chromosome segregationGO:000705920.024
Human
regulation of anatomical structure morphogenesisGO:00226031410.024
cytoplasmic transportGO:00164821150.023
metal ion transportGO:00300012890.023
dendrite morphogenesisGO:0048813430.023
positive regulation of catalytic activityGO:00430851840.023
regulation of neuron differentiationGO:00456642080.023
b cell differentiationGO:003018320.023
cell morphogenesis involved in differentiationGO:00009041190.023
growthGO:00400071650.023
agingGO:00075682410.023
synaptic growth at neuromuscular junctionGO:005112410.023
protein complex biogenesisGO:00702712630.023
negative regulation of apoptotic processGO:00430661810.023
cell motilityGO:00488702020.023
response to growth factorGO:00708481890.023
response to insulinGO:00328681330.023
purine containing compound catabolic processGO:00725231380.023
circadian rhythmGO:0007623880.022
negative regulation of cellular component organizationGO:0051129830.022
positive regulation of cellular amine metabolic processGO:003324030.022
response to corticosteroidGO:00319602350.022
positive regulation of phosphorus metabolic processGO:00105622620.022
regulation of proteasomal protein catabolic processGO:006113640.022
Human
regulation of response to stressGO:00801341260.022
protein modification by small protein conjugationGO:0032446310.022
glycerolipid metabolic processGO:0046486670.021
positive regulation of signalingGO:00230562700.021
nucleoside metabolic processGO:00091161790.021
regulation of secretionGO:00510462240.021
cation homeostasisGO:00550801950.021
organophosphate biosynthetic processGO:00904071430.021
purine nucleoside metabolic processGO:00422781690.021
dna metabolic processGO:0006259960.021
macromolecular complex assemblyGO:00650032730.020
response to extracellular stimulusGO:00099913800.020
calcium ion transmembrane transportGO:0070588700.020
macromolecule localizationGO:00330362520.020
Human
regulation of secretion by cellGO:19035302080.020
carbohydrate derivative metabolic processGO:19011353460.020
nucleoside phosphate metabolic processGO:00067532830.020
muscle tissue developmentGO:0060537580.020
inorganic ion transmembrane transportGO:00986602290.020
cell type specific apoptotic processGO:00972851340.020
negative regulation of multicellular organismal processGO:00512412030.020
positive regulation of intracellular signal transductionGO:19025331380.020
positive regulation of response to stimulusGO:00485842850.020
organelle localizationGO:0051640550.020
Human
negative regulation of molecular functionGO:00440921330.019
Human
cellular response to nitrogen compoundGO:19016992100.019
positive regulation of neurogenesisGO:00507691650.019
positive regulation of secretionGO:00510471400.019
positive regulation of cellular catabolic processGO:0031331710.019
Human
response to nutrientGO:00075842480.019
protein oligomerizationGO:00512591910.019
mitotic cell cycle phase transitionGO:0044772200.019
Human
cellular component morphogenesisGO:00329891550.019
carbohydrate derivative catabolic processGO:19011361470.019
glycosyl compound catabolic processGO:19016581260.019
positive regulation of cell communicationGO:00106472710.019
divalent inorganic cation homeostasisGO:00725071650.019
response to carbohydrateGO:00097431830.019
negative regulation of cellular protein metabolic processGO:00322691060.019
Human
blood circulationGO:00080151830.019
phospholipid metabolic processGO:0006644610.019
regulation of nucleotide metabolic processGO:00061401170.019
protein modification by small protein conjugation or removalGO:0070647350.019
cell adhesionGO:00071551100.019
chromosome organizationGO:0051276360.018
Human
purine ribonucleoside catabolic processGO:00461301240.018
neuron projection morphogenesisGO:00488121220.018
response to alkaloidGO:00432791320.018
purine nucleoside triphosphate metabolic processGO:00091441410.018
establishment of protein localizationGO:00451841410.018
organic cyclic compound catabolic processGO:19013611750.018
positive regulation of cell developmentGO:00107201760.018
tube developmentGO:0035295890.018
cellular ion homeostasisGO:00068731840.018
forebrain developmentGO:0030900980.018
gland developmentGO:00487321550.018
anion transportGO:00068201780.018
negative regulation of signal transductionGO:0009968830.018
positive regulation of cellular component organizationGO:00511302000.018
Human
positive regulation of cellular protein metabolic processGO:00322701670.017
Human
cellular response to growth factor stimulusGO:00713631620.017
organic hydroxy compound metabolic processGO:19016151150.017
response to ethanolGO:00454711620.017
positive regulation of nucleotide metabolic processGO:0045981910.017
regulation of synaptic transmissionGO:00508041410.017
regulation of ion transportGO:00432692450.017
cellular nitrogen compound catabolic processGO:00442701630.017
response to transition metal nanoparticleGO:19902671220.017
monovalent inorganic cation transportGO:00156721720.017
peptidyl amino acid modificationGO:00181931260.017
regulation of protein localizationGO:0032880810.017
Human
response to glucocorticoidGO:00513842230.016
response to radiationGO:00093141370.016
gastrulationGO:000736920.016
localization of cellGO:00516742020.016
amide transportGO:00428861050.016
hormone transportGO:00099141210.016
regulation of purine nucleotide metabolic processGO:19005421150.016
negative regulation of phosphate metabolic processGO:0045936800.016
Human
regulation of immune system processGO:00026821230.016
regulation of membrane potentialGO:00423911100.016
negative regulation of programmed cell deathGO:00430691830.016
regulation of cell cycle phase transitionGO:1901987120.016
Human
organic acid transportGO:00158491160.016
cellular cation homeostasisGO:00300031800.016
negative regulation of signalingGO:00230571570.016
cellular protein localizationGO:00346131220.016
Human
regulation of proteolysisGO:0030162660.016
Human
reactive oxygen species metabolic processGO:0072593370.015
adult locomotory behaviorGO:000834440.015
response to oxidative stressGO:00069791860.015
cell morphogenesis involved in neuron differentiationGO:00486671060.015
steroid metabolic processGO:0008202730.015
lipid biosynthetic processGO:00086101280.015
cellular metal ion homeostasisGO:00068751720.015
response to estrogenGO:00436272320.015
protein transportGO:00150311320.015
cellular response to cytokine stimulusGO:00713451270.015
proteolysisGO:00065081750.015
Human
ribonucleoside metabolic processGO:00091191740.015
transmission of nerve impulseGO:0019226420.015
oxidation reduction processGO:00551143040.015
dephosphorylationGO:0016311980.015
purine ribonucleoside metabolic processGO:00461281680.015
metaphase plate congressionGO:005131010.015
Human
cellular macromolecule localizationGO:00707271220.015
Human
positive regulation of cell projection organizationGO:00313461110.015
neuronal action potentialGO:0019228350.015
divalent inorganic cation transportGO:00725111340.015
organic anion transportGO:00157111320.015
cellular response to acid chemicalGO:0071229750.015
actin cytoskeleton organizationGO:0030036730.015
cellular response to peptide hormone stimulusGO:00713751200.015
g protein coupled receptor signaling pathwayGO:00071862420.015
organophosphate catabolic processGO:00464341480.015
positive regulation of cellular amino acid metabolic processGO:004576410.014
nucleobase containing compound catabolic processGO:00346551520.014
actin filament based processGO:0030029860.014
protein heterooligomerizationGO:0051291890.014
negative regulation of protein metabolic processGO:00512481140.014
Human
organonitrogen compound catabolic processGO:19015651790.014
regulation of neuron projection developmentGO:00109751610.014
carbohydrate biosynthetic processGO:0016051420.014
nucleoside triphosphate metabolic processGO:00091411440.014
cellular response to insulin stimulusGO:0032869810.014
sex differentiationGO:00075481130.014
learning or memoryGO:0007611900.014
multicellular organismal signalingGO:0035637440.014
divalent metal ion transportGO:00708381320.014
neuromuscular synaptic transmissionGO:000727420.014
cell cycle processGO:0022402570.014
Human
negative regulation of nervous system developmentGO:0051961790.014
muscle system processGO:00030121150.014
regulation of neuron deathGO:19012141150.014
cellular response to peptideGO:19016531330.014
signal releaseGO:00230611450.014
response to ketoneGO:19016541820.014
nucleoside catabolic processGO:00091641260.014
gamete generationGO:00072761240.014
single organism carbohydrate metabolic processGO:00447231180.014
positive regulation of protein modification processGO:00314011420.014
negative regulation of developmental processGO:00510931250.014
signal transduction by phosphorylationGO:00230141440.014
calcium ion transportGO:00068161310.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
spermatogenesisGO:0007283990.013
regulation of transmembrane transportGO:00347621220.013
regulation of intracellular transportGO:0032386650.013
ras protein signal transductionGO:0007265290.013
Human
neuron deathGO:00709971270.013
carboxylic acid transportGO:00469421150.013
positive regulation of nervous system developmentGO:00519621780.013
action potentialGO:0001508540.013
establishment of organelle localizationGO:0051656370.013
Human
small gtpase mediated signal transductionGO:0007264360.013
Human
regulation of anatomical structure sizeGO:00900661350.013
positive regulation of phosphorylationGO:00423271770.013
regulation of growthGO:00400081050.013
response to ammonium ionGO:0060359710.013
single organism behaviorGO:00447081300.013
response to glucoseGO:00097491360.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
mitotic cell cycle processGO:1903047350.013
Human
circulatory system processGO:00030131830.013
axis specificationGO:000979840.013
peptide transportGO:0015833970.013
cytokine biosynthetic processGO:004208930.013
immune system developmentGO:0002520410.012
regulation of establishment of protein localizationGO:0070201690.012
protein ubiquitinationGO:0016567280.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
ribonucleotide catabolic processGO:00092611360.012
small molecule biosynthetic processGO:00442831240.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
purine ribonucleotide catabolic processGO:00091541360.012
negative regulation of cell cycle phase transitionGO:190198840.012
protein localization to organelleGO:0033365570.012
Human
ribonucleoside catabolic processGO:00424541260.012
cardiovascular system developmentGO:00723581340.012
positive regulation of neuron differentiationGO:00456661260.012
immune responseGO:00069551040.012
positive regulation of catabolic processGO:0009896780.012
Human
response to reactive oxygen speciesGO:00003021200.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
regulation of neuron apoptotic processGO:0043523830.012
cytokinetic processGO:003250610.012
rho protein signal transductionGO:0007266110.012
negative regulation of mitotic cell cycle phase transitionGO:190199130.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
Human
gonad developmentGO:00084061040.012
multicellular organism growthGO:003526410.012
coenzyme metabolic processGO:0006732860.012
regulation of cell motilityGO:20001451310.012
protein homooligomerizationGO:0051260910.012
spindle organizationGO:000705120.012
generation of precursor metabolites and energyGO:0006091620.012
axon developmentGO:0061564960.012
reproductive system developmentGO:00614581280.012
positive regulation of secretion by cellGO:19035321280.011
reproductive structure developmentGO:00486081280.011
sister chromatid segregationGO:000081910.011
Human
regulation of cell cycle processGO:0010564310.011
Human
guanosine containing compound catabolic processGO:1901069710.011
muscle structure developmentGO:0061061870.011
Human
positive regulation of neuron projection developmentGO:0010976990.011
positive regulation of mapk cascadeGO:0043410920.011
nucleoside phosphate catabolic processGO:19012921400.011
telencephalon developmentGO:0021537620.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
regulation of peptide transportGO:0090087870.011
response to hydrogen peroxideGO:0042542890.011
regulation of nucleoside metabolic processGO:0009118660.011
development of primary sexual characteristicsGO:00451371070.011
regulation of cytokine biosynthetic processGO:004203530.011
regulation of response to external stimulusGO:00321011060.011
calcium ion homeostasisGO:00550741620.011
glucose metabolic processGO:0006006520.011
purine nucleoside catabolic processGO:00061521240.011
nucleotide catabolic processGO:00091661390.011
regulation of lipid metabolic processGO:0019216680.011
Human
positive regulation of protein phosphorylationGO:00019341350.011
gtp catabolic processGO:0006184710.011
circulatory system developmentGO:00723591340.011
cyclic nucleotide metabolic processGO:0009187800.011
erythrocyte differentiationGO:003021810.011
carbohydrate metabolic processGO:00059751300.011
regulation of nucleocytoplasmic transportGO:0046822280.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.011
Human
regulation of cellular response to stressGO:0080135490.011
single organism membrane organizationGO:0044802740.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
neuron projection guidanceGO:0097485240.010
cellular calcium ion homeostasisGO:00068741600.010
cellular response to organic cyclic compoundGO:00714072020.010
anatomical structure formation involved in morphogenesisGO:0048646830.010
chemosensory behaviorGO:000763520.010
ovulation cycleGO:0042698670.010
establishment of chromosome localizationGO:005130310.010
Human
alcohol metabolic processGO:0006066770.010
regulation of purine nucleotide catabolic processGO:0033121650.010
purine nucleoside triphosphate catabolic processGO:00091461220.010
embryo developmentGO:0009790490.010
regulation of mitotic cell cycle phase transitionGO:1901990110.010
Human
hormone secretionGO:00468791150.010
early endosome to late endosome transportGO:004502220.010
response to hexoseGO:00097461440.010
fertilizationGO:000956630.010
male gamete generationGO:0048232990.010
dna damage checkpointGO:000007720.010
central nervous system neuron axonogenesisGO:002195510.010

Rb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.034
central nervous system diseaseDOID:33100.015