Rattus norvegicus

28 known processes

Clcn5

chloride channel 5

(Aliases: CLC5)

Clcn5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to extracellular stimulusGO:00099913800.569
cellular response to endogenous stimulusGO:00714953770.562
cellular response to organic cyclic compoundGO:00714072020.510
cellular response to alcoholGO:0097306870.496
cellular response to oxygen containing compoundGO:19017013860.470
response to peptide hormoneGO:00434342780.465
cellular response to organonitrogen compoundGO:00714171970.399
rna biosynthetic processGO:00327743800.371
lipid metabolic processGO:00066292830.322
transcription from rna polymerase ii promoterGO:00063662520.317
regulation of rna metabolic processGO:00512523910.312
response to carbohydrateGO:00097431830.292
regulation of nervous system developmentGO:00519602640.290
cellular response to nitrogen compoundGO:19016992100.288
response to glucocorticoidGO:00513842230.287
regulation of rna biosynthetic processGO:20011413810.281
response to nutrient levelsGO:00316673700.276
response to monosaccharideGO:00342841590.265
cellular response to tumor necrosis factorGO:0071356460.265
positive regulation of biosynthetic processGO:00098913190.259
single organism biosynthetic processGO:00447113420.251
ion homeostasisGO:00508012120.241
Yeast
response to external biotic stimulusGO:00432072210.240
response to inorganic substanceGO:00100353770.236
cellular component assemblyGO:00226073600.229
response to corticosteroidGO:00319602350.227
response to peptideGO:19016522920.219
positive regulation of developmental processGO:00510942830.197
positive regulation of transcription dna templatedGO:00458931970.194
hormone transportGO:00099141210.188
regulation of transcription from rna polymerase ii promoterGO:00063572340.184
response to lipopolysaccharideGO:00324961910.180
localization of cellGO:00516742020.179
positive regulation of cellular component organizationGO:00511302000.177
cellular component movementGO:00069282480.174
organelle organizationGO:00069962660.172
response to vitaminGO:00332731310.171
cell projection organizationGO:00300303020.167
cell migrationGO:00164771970.165
positive regulation of gene expressionGO:00106282440.165
positive regulation of rna biosynthetic processGO:19026801970.163
positive regulation of cellular biosynthetic processGO:00313282950.161
positive regulation of multicellular organismal processGO:00512403870.161
head developmentGO:00603222470.161
positive regulation of cell communicationGO:00106472710.160
response to nutrientGO:00075842480.160
positive regulation of nucleic acid templated transcriptionGO:19035081970.159
cellular chemical homeostasisGO:00550822470.154
Yeast
positive regulation of nitrogen compound metabolic processGO:00511733340.152
response to metal ionGO:00100382530.150
nucleic acid templated transcriptionGO:00976593790.146
rna metabolic processGO:00160704060.145
wound healingGO:00420601220.145
regulation of cellular component movementGO:00512701500.144
positive regulation of cellular protein metabolic processGO:00322701670.144
positive regulation of transportGO:00510502450.142
positive regulation of macromolecule biosynthetic processGO:00105572470.138
neuron differentiationGO:00301823680.135
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.134
response to acid chemicalGO:00011012220.132
response to bacteriumGO:00096172000.132
programmed cell deathGO:00125013920.130
response to biotic stimulusGO:00096072260.127
organophosphate metabolic processGO:00196373700.123
regulation of phosphate metabolic processGO:00192203490.123
regulation of nucleic acid templated transcriptionGO:19035063800.122
amine metabolic processGO:0009308380.120
monosaccharide metabolic processGO:0005996610.119
cellular ketone metabolic processGO:0042180510.118
response to woundingGO:00096112540.116
negative regulation of nucleic acid templated transcriptionGO:19035071170.111
blood circulationGO:00080151830.111
regulation of phosphorus metabolic processGO:00511743490.109
cellular component biogenesisGO:00440853680.107
negative regulation of macromolecule metabolic processGO:00106052600.107
regulation of neuron projection developmentGO:00109751610.106
regulation of cell differentiationGO:00455953200.106
cellular response to hormone stimulusGO:00328702470.102
positive regulation of locomotionGO:00400171020.101
regulation of cell developmentGO:00602842630.100
negative regulation of rna metabolic processGO:00512531230.099
positive regulation of cellular component movementGO:00512721020.098
cellular response to growth factor stimulusGO:00713631620.097
response to radiationGO:00093141370.097
cellular response to lipidGO:00713962010.096
macromolecular complex subunit organizationGO:00439333390.095
regulation of neuron differentiationGO:00456642080.095
single organism carbohydrate metabolic processGO:00447231180.094
intracellular signal transductionGO:00355563140.093
regulation of signal transductionGO:00099663180.093
regulation of molecular functionGO:00650093980.093
anatomical structure morphogenesisGO:00096532980.093
response to other organismGO:00517072200.092
negative regulation of response to stimulusGO:00485851550.091
cell motilityGO:00488702020.091
regulation of transcription dna templatedGO:00063553740.091
hormone secretionGO:00468791150.091
regulation of cellular localizationGO:00603412630.089
regulation of system processGO:00440572080.088
negative regulation of rna biosynthetic processGO:19026791180.087
apoptotic processGO:00069153810.087
chemical homeostasisGO:00488782920.087
Yeast
nitrogen compound transportGO:00717052290.086
neuron developmentGO:00486662860.086
cellular response to cytokine stimulusGO:00713451270.086
response to hexoseGO:00097461440.086
multi organism reproductive processGO:00447032620.085
response to growth factorGO:00708481890.085
response to estradiolGO:00323551640.085
protein complex subunit organizationGO:00718223020.085
calcitriol biosynthetic process from calciolGO:003637820.084
regenerationGO:00310991630.083
response to alkaloidGO:00432791320.083
positive regulation of signalingGO:00230562700.083
lipid biosynthetic processGO:00086101280.082
transcription dna templatedGO:00063513770.081
circulatory system processGO:00030131830.080
anterior posterior pattern specificationGO:000995210.080
response to amino acidGO:0043200750.080
g protein coupled receptor signaling pathwayGO:00071862420.078
organic substance catabolic processGO:19015753160.077
cellular amino acid metabolic processGO:00065201070.077
regulation of organelle organizationGO:0033043800.077
cellular metal ion homeostasisGO:00068751720.076
Yeast
regulation of cell morphogenesis involved in differentiationGO:0010769720.076
carboxylic acid metabolic processGO:00197522890.075
positive regulation of signal transductionGO:00099671750.075
endocytosisGO:0006897840.075
Mouse
regulation of neurogenesisGO:00507672470.075
protein phosphorylationGO:00064683450.074
homeostatic processGO:00425923310.074
Yeast
cellular homeostasisGO:00197252520.073
Yeast
cell morphogenesis involved in differentiationGO:00009041190.073
negative regulation of gene expressionGO:00106291990.072
response to ketoneGO:19016541820.072
response to insulinGO:00328681330.070
positive regulation of molecular functionGO:00440932300.070
macromolecular complex assemblyGO:00650032730.069
cell morphogenesisGO:00009021420.067
positive regulation of rna metabolic processGO:00512542030.067
oxoacid metabolic processGO:00434362900.066
regulation of anatomical structure morphogenesisGO:00226031410.065
regulation of protein modification processGO:00313991940.065
regulation of protein phosphorylationGO:00019321830.065
cellular response to metal ionGO:0071248550.065
oxidation reduction processGO:00551143040.064
organic acid metabolic processGO:00060822920.064
regulation of dendrite developmentGO:0050773590.063
cellular amine metabolic processGO:0044106380.063
metal ion homeostasisGO:00550651860.063
Yeast
regulation of cellular ketone metabolic processGO:0010565270.062
regulation of heart contractionGO:0008016480.062
single organism catabolic processGO:00447122830.061
regulation of cellular component organizationGO:00511283680.061
agingGO:00075682410.061
muscle tissue developmentGO:0060537580.060
defense responseGO:00069521940.060
regulation of phosphorylationGO:00423252480.060
cellular lipid metabolic processGO:00442552080.060
regulation of cell motilityGO:20001451310.060
regulation of cellular amino acid metabolic processGO:000652120.060
positive regulation of cell differentiationGO:00455972170.059
neurological system processGO:00508772190.058
divalent inorganic cation homeostasisGO:00725071650.058
regulation of protein metabolic processGO:00512462890.058
catabolic processGO:00090563510.057
locomotionGO:00400112370.057
negative regulation of multicellular organismal processGO:00512412030.057
negative regulation of nitrogen compound metabolic processGO:00511721610.056
regulation of catalytic activityGO:00507903040.055
cellular response to peptideGO:19016531330.054
regulation of muscle system processGO:0090257790.053
muscle system processGO:00030121150.053
neuron projection developmentGO:00311752730.053
response to cytokineGO:00340972150.052
macromolecule localizationGO:00330362520.052
secretionGO:00469033070.052
regulation of cell migrationGO:00303341280.052
reproductive processGO:00224143720.052
positive regulation of neuron projection developmentGO:0010976990.051
negative regulation of programmed cell deathGO:00430691830.051
regulation of locomotionGO:00400121480.050
carbohydrate metabolic processGO:00059751300.050
regulation of cell projection organizationGO:00313441750.050
signal releaseGO:00230611450.050
cellular response to steroid hormone stimulusGO:0071383930.050
positive regulation of neurogenesisGO:00507691650.050
response to glucoseGO:00097491360.049
negative regulation of nucleobase containing compound metabolic processGO:00459341530.049
response to vitamin dGO:0033280340.049
secretion by cellGO:00329402480.049
single organism organelle organizationGO:19025891800.048
protein complex assemblyGO:00064612630.048
purine containing compound metabolic processGO:00725212530.048
organophosphate biosynthetic processGO:00904071430.048
regulation of secretion by cellGO:19035302080.048
positive regulation of organelle organizationGO:0010638480.048
response to molecule of bacterial originGO:00022371940.047
development of primary sexual characteristicsGO:00451371070.047
cellular response to peptide hormone stimulusGO:00713751200.047
negative regulation of transcription dna templatedGO:00458921160.047
cell cell signalingGO:00072673350.046
cellular ion homeostasisGO:00068731840.046
Yeast
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.045
mapk cascadeGO:00001651400.045
negative regulation of cell differentiationGO:0045596990.045
regulation of programmed cell deathGO:00430673410.045
regulation of cell proliferationGO:00421273590.045
regulation of hormone levelsGO:00108171870.044
positive regulation of neuron differentiationGO:00456661260.044
metal ion transportGO:00300012890.044
positive regulation of cell developmentGO:00107201760.044
positive regulation of response to stimulusGO:00485842850.044
cellular divalent inorganic cation homeostasisGO:00725031620.044
gland developmentGO:00487321550.044
positive regulation of cytosolic calcium ion concentrationGO:00072041220.044
cellular response to stressGO:00335542690.043
cellular response to glucocorticoid stimulusGO:0071385680.043
response to mechanical stimulusGO:00096121340.043
Rat
negative regulation of transportGO:00510511360.043
brain developmentGO:00074202470.043
central nervous system developmentGO:00074173110.043
response to activityGO:0014823730.043
aromatic compound catabolic processGO:00194391680.042
negative regulation of cell developmentGO:0010721820.042
hepaticobiliary system developmentGO:0061008900.041
embryonic skeletal system developmentGO:004870630.041
response to tumor necrosis factorGO:0034612560.041
arginine metabolic processGO:000652560.040
regulation of peptide transportGO:0090087870.040
small molecule biosynthetic processGO:00442831240.040
regulation of multicellular organismal developmentGO:20000263760.040
regulation of intracellular signal transductionGO:19025312180.040
negative regulation of cellular metabolic processGO:00313242810.040
response to nicotineGO:0035094510.040
negative regulation of metabolic processGO:00098923310.039
nucleoside phosphate metabolic processGO:00067532830.039
regulation of cellular amine metabolic processGO:003323880.039
liver developmentGO:0001889900.039
glycosyl compound metabolic processGO:19016571820.039
neuron projection morphogenesisGO:00488121220.039
positive regulation of cell projection organizationGO:00313461110.038
multi multicellular organism processGO:00447061380.038
single organism reproductive processGO:00447022970.038
vitamin d receptor signaling pathwayGO:007056110.037
positive regulation of nucleobase containing compound metabolic processGO:00459353190.037
positive regulation of protein modification processGO:00314011420.037
immune responseGO:00069551040.037
regulation of homeostatic processGO:00328441010.037
membrane organizationGO:0061024940.037
signal transduction by phosphorylationGO:00230141440.037
immune system processGO:00023762040.037
negative regulation of signalingGO:00230571570.037
lymphocyte activationGO:0046649430.036
positive regulation of programmed cell deathGO:00430681570.036
single organism intracellular transportGO:19025821660.036
reproductive system developmentGO:00614581280.036
reproductive structure developmentGO:00486081280.035
vitamin a metabolic processGO:000677620.035
regulation of apoptotic processGO:00429813350.035
response to estrogenGO:00436272320.035
regulation of cellular component biogenesisGO:0044087860.035
regulation of blood circulationGO:19035221100.035
nucleobase containing small molecule metabolic processGO:00550863160.034
regulation of secretionGO:00510462240.034
calcium ion transportGO:00068161310.034
positive regulation of protein metabolic processGO:00512471780.034
phospholipid metabolic processGO:0006644610.034
cellular catabolic processGO:00442482950.033
positive regulation of phosphate metabolic processGO:00459372620.033
anion transportGO:00068201780.033
female pregnancyGO:00075651220.033
response to purine containing compoundGO:00140741260.033
response to interleukin 1GO:0070555550.033
establishment of protein localizationGO:00451841410.033
carbohydrate derivative metabolic processGO:19011353460.033
regulation of response to external stimulusGO:00321011060.032
cell part morphogenesisGO:00329901230.032
cellular component morphogenesisGO:00329891550.032
sensory organ developmentGO:0007423740.032
cell projection morphogenesisGO:00488581230.032
protein localizationGO:00081041910.032
nucleotide metabolic processGO:00091172790.032
regulation of cellular protein metabolic processGO:00322682670.031
negative regulation of cell proliferationGO:00082851190.031
protein transportGO:00150311320.031
regulation of vesicle mediated transportGO:0060627810.031
response to mineralocorticoidGO:0051385490.031
neural crest cell developmentGO:001403220.031
regulation of insulin secretionGO:0050796650.031
locomotor rhythmGO:004547510.031
response to temperature stimulusGO:0009266940.031
protein complex biogenesisGO:00702712630.030
inorganic cation transmembrane transportGO:00986622020.030
positive regulation of cell migrationGO:0030335960.030
muscle cell proliferationGO:0033002840.029
endomembrane system organizationGO:0010256480.029
multicellular organismal reproductive processGO:00486092330.029
cellular response to external stimulusGO:00714961180.029
regulation of immune system processGO:00026821230.029
negative regulation of cellular biosynthetic processGO:00313271610.029
embryonic cranial skeleton morphogenesisGO:004870120.029
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.028
alpha amino acid metabolic processGO:1901605710.028
cellular calcium ion homeostasisGO:00068741600.028
cellular response to interleukin 1GO:0071347370.028
cell substrate adhesionGO:0031589290.028
sex differentiationGO:00075481130.028
cellular response to ketoneGO:1901655510.028
olfactory bulb interneuron differentiationGO:002188910.028
circulatory system developmentGO:00723591340.028
regulation of dendrite morphogenesisGO:0048814330.028
cardiovascular system developmentGO:00723581340.027
negative regulation of apoptotic processGO:00430661810.027
acute phase responseGO:0006953200.027
positive regulation of cell motilityGO:2000147970.027
response to oxygen levelsGO:00704822650.027
positive regulation of protein phosphorylationGO:00019341350.027
multicellular organismal homeostasisGO:0048871490.027
response to organophosphorusGO:00466831020.027
calcium ion homeostasisGO:00550741620.027
cellular response to inorganic substanceGO:0071241650.026
gliogenesisGO:0042063930.026
eye morphogenesisGO:004859240.026
organic hydroxy compound metabolic processGO:19016151150.026
actin filament based processGO:0030029860.026
nucleoside metabolic processGO:00091161790.026
negative regulation of biosynthetic processGO:00098901680.026
developmental process involved in reproductionGO:00030061590.025
response to calcium ionGO:0051592590.025
organic cyclic compound catabolic processGO:19013611750.025
regulation of blood vessel sizeGO:0050880890.025
negative regulation of signal transductionGO:0009968830.025
positive regulation of cell proliferationGO:00082842490.024
regulation of phagocytosis engulfmentGO:006009940.024
negative regulation of cell deathGO:00605482290.024
response to ethanolGO:00454711620.024
purine nucleotide metabolic processGO:00061632290.024
cation homeostasisGO:00550801950.024
Yeast
response to decreased oxygen levelsGO:00362932370.024
acute inflammatory responseGO:0002526580.024
cellular response to campGO:0071320260.024
eye developmentGO:0001654500.024
innate immune responseGO:0045087350.024
positive regulation of phosphorus metabolic processGO:00105622620.024
peptidyl amino acid modificationGO:00181931260.024
sequestering of calcium ionGO:005120880.023
coenzyme metabolic processGO:0006732860.023
small gtpase mediated signal transductionGO:0007264360.023
regulation of peptide secretionGO:0002791820.023
regulation of phosphatidylinositol dephosphorylationGO:006030410.023
organic hydroxy compound biosynthetic processGO:1901617510.023
purine containing compound catabolic processGO:00725231380.023
negative regulation of cell communicationGO:00106481580.023
regulation of hormone secretionGO:00468831060.023
negative regulation of secretionGO:0051048820.023
sensory perceptionGO:00076001010.023
response to ammonium ionGO:0060359710.023
sequestering of metal ionGO:005123890.023
blood vessel developmentGO:0001568690.022
positive regulation of hormone secretionGO:0046887650.022
multicellular organismal signalingGO:0035637440.022
response to starvationGO:0042594590.022
insulin secretionGO:0030073690.022
regulation of calcium ion transportGO:0051924770.022
vascular process in circulatory systemGO:0003018960.022
renal system developmentGO:0072001670.022
striated muscle tissue developmentGO:0014706580.022
inflammatory responseGO:00069541500.021
response to corticosteroneGO:0051412400.021
alcohol metabolic processGO:0006066770.021
cellular macromolecule localizationGO:00707271220.021
organonitrogen compound biosynthetic processGO:19015661670.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
regulation of cell adhesionGO:0030155520.021
ribonucleoside metabolic processGO:00091191740.021
regulation of neuron deathGO:19012141150.021
cellular response to extracellular stimulusGO:0031668730.021
regulation of transferase activityGO:00513381230.021
developmental growthGO:00485891000.021
positive regulation of secretion by cellGO:19035321280.021
positive regulation of catalytic activityGO:00430851840.021
purine nucleoside metabolic processGO:00422781690.021
behaviorGO:00076102050.021
digestive system developmentGO:0055123410.020
vesicle organizationGO:0016050290.020
purine ribonucleotide metabolic processGO:00091502270.020
vasculature developmentGO:0001944700.020
single organism membrane organizationGO:0044802740.020
organelle localizationGO:0051640550.020
glucose homeostasisGO:0042593750.020
nucleoside triphosphate metabolic processGO:00091411440.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
reproductionGO:00000032450.019
maintenance of locationGO:0051235170.019
regulation of cell morphogenesisGO:0022604770.019
divalent metal ion transportGO:00708381320.019
lipid localizationGO:0010876620.019
single organism behaviorGO:00447081300.019
gonad developmentGO:00084061040.019
amide transportGO:00428861050.019
regulation of cyclic nucleotide metabolic processGO:0030799510.019
response to heatGO:0009408600.019
cellular nitrogen compound catabolic processGO:00442701630.019
circadian regulation of gene expressionGO:003292230.019
ossificationGO:0001503700.019
response to electrical stimulusGO:0051602560.019
regulation of response to stressGO:00801341260.018
vitamin biosynthetic processGO:000911030.018
embryonic skeletal system morphogenesisGO:004870430.018
regulation of intracellular transportGO:0032386650.018
negative regulation of pancreatic stellate cell proliferationGO:200023010.018
embryonic pattern specificationGO:000988010.018
tube developmentGO:0035295890.018
regulation of protein kinase activityGO:00458591050.018
regulation of lipid biosynthetic processGO:0046890380.018
positive regulation of secretionGO:00510471400.017
urogenital system developmentGO:0001655780.017
taxisGO:0042330670.017
energy derivation by oxidation of organic compoundsGO:0015980460.017
carbohydrate derivative biosynthetic processGO:19011371240.017
glucose metabolic processGO:0006006520.017
hexose metabolic processGO:0019318580.017
heat acclimationGO:001028610.017
positive regulation of cell deathGO:00109421840.017
action potentialGO:0001508540.017
cytosolic calcium ion homeostasisGO:00514801400.017
activation of cysteine type endopeptidase activityGO:009720240.017
ras protein signal transductionGO:0007265290.017
rhythmic processGO:00485111560.017
monocarboxylic acid metabolic processGO:00327871520.017
vesicle localizationGO:0051648330.017
cytoplasmic transportGO:00164821150.017
leukocyte activationGO:0045321760.017
carbohydrate homeostasisGO:0033500750.017
regulation of canonical wnt signaling pathwayGO:006082840.017
positive regulation of apoptotic processGO:00430651540.017
ribose phosphate metabolic processGO:00196932350.017
cell cycleGO:00070491010.017
positive regulation of nervous system developmentGO:00519621780.017
neuron deathGO:00709971270.016
fat soluble vitamin biosynthetic processGO:004236220.016
kidney developmentGO:0001822670.016
ovulation cycleGO:0042698670.016
response to campGO:0051591910.016
ion transmembrane transportGO:00342203650.016
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.016
regulation of hydrolase activityGO:00513361430.016
axon developmentGO:0061564960.016
response to reactive oxygen speciesGO:00003021200.016
dendrite developmentGO:0016358720.016
negative regulation of neurogenesisGO:0050768780.016
regulation of catabolic processGO:00098941130.016
cellular response to nutrient levelsGO:0031669600.016
negative regulation of molecular functionGO:00440921330.016
purine ribonucleoside metabolic processGO:00461281680.016
neuronal action potentialGO:0019228350.016
axonogenesisGO:0007409710.016
regulation of peptide hormone secretionGO:0090276800.016
positive regulation of intracellular signal transductionGO:19025331380.015
organ regenerationGO:00311001010.015
positive regulation of hydrolase activityGO:0051345860.015
lens development in camera type eyeGO:0002088130.015
cellular response to biotic stimulusGO:0071216590.015
negative regulation of phosphorus metabolic processGO:0010563800.015
cellular response to molecule of bacterial originGO:0071219560.015
heterocycle catabolic processGO:00467001670.015
heart developmentGO:0007507720.015
protein autophosphorylationGO:0046777660.015
peptide transportGO:0015833970.015
regulation of immune responseGO:0050776550.014
protein homooligomerizationGO:0051260910.014
cytosolic calcium ion transportGO:0060401390.014
cation transportGO:00068123820.014
response to hypoxiaGO:00016662310.014
lens fiber cell differentiationGO:007030630.014
heat generationGO:0031649110.014
forebrain developmentGO:0030900980.014
positive regulation of phagocytosis engulfmentGO:006010040.014
transmembrane transportGO:00550854120.014
limb morphogenesisGO:003510840.014
embryo developmentGO:0009790490.014
peptide hormone secretionGO:0030072840.014
epithelium developmentGO:0060429960.014
cellular response to hexose stimulusGO:0071331650.014
pancreatic stellate cell proliferationGO:007234320.014

Clcn5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.036
vascular diseaseDOID:17800.036
artery diseaseDOID:005082800.036
disease of anatomical entityDOID:700.036
musculoskeletal system diseaseDOID:1700.021
connective tissue diseaseDOID:6500.021
hypertensionDOID:1076300.017
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
disease of metabolismDOID:001466700.015
Human