Rattus norvegicus

32 known processes

Scn1b

sodium channel, voltage-gated, type I, beta

Scn1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inorganic cation transmembrane transportGO:00986622020.371
cation transmembrane transportGO:00986552630.329
regulation of rna metabolic processGO:00512523910.289
programmed cell deathGO:00125013920.267
muscle system processGO:00030121150.267
neurological system processGO:00508772190.243
cation transportGO:00068123820.232
transmembrane transportGO:00550854120.200
cell cell signalingGO:00072673350.158
ion transmembrane transportGO:00342203650.155
inorganic ion transmembrane transportGO:00986602290.143
muscle contractionGO:0006936880.133
positive regulation of transportGO:00510502450.129
positive regulation of multicellular organismal processGO:00512403870.122
secretion by cellGO:00329402480.120
metal ion transportGO:00300012890.112
blood circulationGO:00080151830.111
reproductive processGO:00224143720.108
circulatory system processGO:00030131830.106
cellular component assemblyGO:00226073600.106
secretionGO:00469033070.106
apoptotic processGO:00069153810.101
positive regulation of apoptotic processGO:00430651540.101
positive regulation of macromolecule biosynthetic processGO:00105572470.097
regulation of system processGO:00440572080.096
regulation of transcription dna templatedGO:00063553740.096
regulation of multicellular organismal developmentGO:20000263760.096
chemical homeostasisGO:00488782920.095
regulation of blood vessel sizeGO:0050880890.094
organophosphate metabolic processGO:00196373700.093
cellular homeostasisGO:00197252520.093
regulation of apoptotic processGO:00429813350.092
cellular component biogenesisGO:00440853680.088
cellular response to oxygen containing compoundGO:19017013860.085
positive regulation of nitrogen compound metabolic processGO:00511733340.083
positive regulation of cell deathGO:00109421840.082
action potentialGO:0001508540.079
transcription from rna polymerase ii promoterGO:00063662520.079
regulation of programmed cell deathGO:00430673410.079
metal ion homeostasisGO:00550651860.079
regulation of membrane potentialGO:00423911100.079
intracellular signal transductionGO:00355563140.079
cellular cation homeostasisGO:00300031800.077
transcription dna templatedGO:00063513770.076
cellular calcium ion homeostasisGO:00068741600.076
regulation of transmembrane transportGO:00347621220.075
homeostatic processGO:00425923310.075
regulation of nucleic acid templated transcriptionGO:19035063800.075
regulation of neuron differentiationGO:00456642080.075
cellular response to organic cyclic compoundGO:00714072020.074
regulation of cell maturationGO:190342930.074
regulation of rna biosynthetic processGO:20011413810.073
rna metabolic processGO:00160704060.072
multi organism reproductive processGO:00447032620.071
cellular chemical homeostasisGO:00550822470.069
neuron differentiationGO:00301823680.069
response to ketoneGO:19016541820.068
cation homeostasisGO:00550801950.066
negative regulation of signalingGO:00230571570.065
synaptic transmissionGO:00072682350.064
cellular response to external stimulusGO:00714961180.064
calcium ion transportGO:00068161310.063
sodium ion transmembrane transportGO:0035725670.063
reproductionGO:00000032450.062
regulation of metal ion transportGO:00109591180.061
negative regulation of metabolic processGO:00098923310.061
regulation of cell differentiationGO:00455953200.060
response to estrogenGO:00436272320.059
cellular response to stressGO:00335542690.057
regulation of muscle system processGO:0090257790.057
protein localizationGO:00081041910.056
negative regulation of response to stimulusGO:00485851550.055
response to extracellular stimulusGO:00099913800.054
central nervous system developmentGO:00074173110.054
cellular response to endogenous stimulusGO:00714953770.053
divalent metal ion transportGO:00708381320.053
rna biosynthetic processGO:00327743800.052
transmission of nerve impulseGO:0019226420.052
regulation of blood circulationGO:19035221100.052
cellular response to organonitrogen compoundGO:00714171970.051
neuron developmentGO:00486662860.051
neuron projection developmentGO:00311752730.051
negative regulation of macromolecule metabolic processGO:00106052600.051
multicellular organismal reproductive processGO:00486092330.051
regulation of transcription from rna polymerase ii promoterGO:00063572340.050
vascular process in circulatory systemGO:0003018960.050
oxoacid metabolic processGO:00434362900.049
behaviorGO:00076102050.049
positive regulation of nucleobase containing compound metabolic processGO:00459353190.049
regulation of anatomical structure sizeGO:00900661350.049
catabolic processGO:00090563510.048
regulation of cellular localizationGO:00603412630.048
macromolecular complex subunit organizationGO:00439333390.048
negative regulation of rna metabolic processGO:00512531230.047
regulation of cellular amine metabolic processGO:003323880.047
cellular ketone metabolic processGO:0042180510.046
cellular metal ion homeostasisGO:00068751720.046
regulation of nervous system developmentGO:00519602640.046
neuron projection morphogenesisGO:00488121220.046
rhythmic processGO:00485111560.046
positive regulation of cellular biosynthetic processGO:00313282950.045
regulation of synaptic transmissionGO:00508041410.045
multicellular organism reproductionGO:00325042330.045
cellular divalent inorganic cation homeostasisGO:00725031620.045
single organism reproductive processGO:00447022970.044
regulation of cell proliferationGO:00421273590.044
positive regulation of rna metabolic processGO:00512542030.043
positive regulation of biosynthetic processGO:00098913190.043
regulation of cellular ketone metabolic processGO:0010565270.043
regulation of secretionGO:00510462240.043
cognitionGO:0050890920.043
head developmentGO:00603222470.043
negative regulation of cell communicationGO:00106481580.042
protein complex assemblyGO:00064612630.042
response to estradiolGO:00323551640.042
regulation of striated muscle contractionGO:0006942210.041
positive regulation of molecular functionGO:00440932300.041
neuronal action potentialGO:0019228350.041
organic substance catabolic processGO:19015753160.041
positive regulation of rna biosynthetic processGO:19026801970.040
multicellular organismal signalingGO:0035637440.040
purine containing compound biosynthetic processGO:0072522850.039
regulation of ion transmembrane transporter activityGO:0032412480.039
macromolecule localizationGO:00330362520.039
lipid metabolic processGO:00066292830.038
heart processGO:0003015570.038
macromolecular complex assemblyGO:00650032730.038
cellular response to lipidGO:00713962010.038
cell projection organizationGO:00300303020.038
ion homeostasisGO:00508012120.038
regulation of cellular protein metabolic processGO:00322682670.038
positive regulation of programmed cell deathGO:00430681570.038
single organism behaviorGO:00447081300.038
agingGO:00075682410.038
protein complex subunit organizationGO:00718223020.037
growthGO:00400071650.037
nucleic acid templated transcriptionGO:00976593790.037
positive regulation of nucleic acid templated transcriptionGO:19035081970.037
sodium ion transportGO:0006814820.037
protein complex biogenesisGO:00702712630.037
cellular response to nitrogen compoundGO:19016992100.037
regulation of ion transmembrane transportGO:00347651210.036
anterior posterior pattern specificationGO:000995210.035
regulation of ion transportGO:00432692450.035
synapse organizationGO:0050808460.035
regulation of neuron projection developmentGO:00109751610.035
organic acid metabolic processGO:00060822920.034
negative regulation of gene expressionGO:00106291990.034
signal releaseGO:00230611450.034
cellular component morphogenesisGO:00329891550.034
negative regulation of cellular metabolic processGO:00313242810.033
regulation of transmembrane transporter activityGO:0022898490.033
negative regulation of molecular functionGO:00440921330.033
regulation of molecular functionGO:00650093980.033
regulation of tube sizeGO:0035150890.033
myelinationGO:0042552390.033
response to oxidative stressGO:00069791860.033
negative regulation of nucleic acid templated transcriptionGO:19035071170.032
nucleobase containing small molecule metabolic processGO:00550863160.032
response to oxygen levelsGO:00704822650.032
positive regulation of neurogenesisGO:00507691650.031
regulation of synaptic plasticityGO:0048167700.031
negative regulation of biosynthetic processGO:00098901680.031
regulation of cellular amino acid metabolic processGO:000652120.031
protein phosphorylationGO:00064683450.031
positive regulation of transcription dna templatedGO:00458931970.031
positive regulation of cell differentiationGO:00455972170.031
regulation of homeostatic processGO:00328441010.031
response to mechanical stimulusGO:00096121340.030
regulation of neurogenesisGO:00507672470.030
monovalent inorganic cation transportGO:00156721720.030
regulation of cell developmentGO:00602842630.030
apoptotic signaling pathwayGO:0097190270.030
response to molecule of bacterial originGO:00022371940.030
regulation of hormone levelsGO:00108171870.030
organelle organizationGO:00069962660.029
regulation of cell morphogenesis involved in differentiationGO:0010769720.029
cellular catabolic processGO:00442482950.029
cellular amino acid metabolic processGO:00065201070.029
neuron apoptotic processGO:0051402880.029
muscle structure developmentGO:0061061870.029
organophosphate biosynthetic processGO:00904071430.029
cellular potassium ion transportGO:0071804720.029
protein homooligomerizationGO:0051260910.028
cellular response to hormone stimulusGO:00328702470.028
anatomical structure morphogenesisGO:00096532980.028
response to nutrient levelsGO:00316673700.028
regulation of transporter activityGO:0032409500.027
negative regulation of signal transductionGO:0009968830.027
positive regulation of nervous system developmentGO:00519621780.027
divalent inorganic cation transportGO:00725111340.027
axis specificationGO:000979840.027
positive regulation of synapse maturationGO:009012920.027
proteolysisGO:00065081750.027
defense responseGO:00069521940.026
purine nucleotide biosynthetic processGO:0006164830.026
glucose homeostasisGO:0042593750.026
learning or memoryGO:0007611900.026
positive regulation of purine nucleotide metabolic processGO:1900544910.026
peptide hormone secretionGO:0030072840.026
response to glucoseGO:00097491360.026
cellular macromolecule localizationGO:00707271220.026
brain developmentGO:00074202470.026
g protein coupled receptor signaling pathwayGO:00071862420.025
organonitrogen compound biosynthetic processGO:19015661670.025
phospholipid metabolic processGO:0006644610.025
protein oligomerizationGO:00512591910.025
gliogenesisGO:0042063930.025
regulation of peptide secretionGO:0002791820.025
calcium ion transmembrane transportGO:0070588700.025
response to bacteriumGO:00096172000.025
chemosensory behaviorGO:000763520.025
multi multicellular organism processGO:00447061380.024
negative regulation of apoptotic processGO:00430661810.024
regulation of proteasomal protein catabolic processGO:006113640.024
carbohydrate derivative biosynthetic processGO:19011371240.024
purine containing compound metabolic processGO:00725212530.024
positive regulation of cellular component organizationGO:00511302000.024
purine nucleotide metabolic processGO:00061632290.024
positive regulation of cell developmentGO:00107201760.024
reproductive structure developmentGO:00486081280.024
single organism biosynthetic processGO:00447113420.024
positive regulation of developmental processGO:00510942830.024
response to monosaccharideGO:00342841590.024
gamete generationGO:00072761240.024
positive regulation of cell projection organizationGO:00313461110.024
positive regulation of cellular catabolic processGO:0031331710.023
regulation of cell projection organizationGO:00313441750.023
regulation of cellular component organizationGO:00511283680.023
positive regulation of secretionGO:00510471400.023
cell morphogenesisGO:00009021420.023
negative regulation of nitrogen compound metabolic processGO:00511721610.023
response to metal ionGO:00100382530.022
negative regulation of cell deathGO:00605482290.022
nitrogen compound transportGO:00717052290.022
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.022
amine metabolic processGO:0009308380.022
regulation of neurological system processGO:0031644430.022
carbohydrate metabolic processGO:00059751300.022
regulation of signal transductionGO:00099663180.022
embryonic pattern specificationGO:000988010.021
negative regulation of programmed cell deathGO:00430691830.021
axon ensheathmentGO:0008366400.021
cellular response to oxidative stressGO:0034599760.021
regulation of lipid metabolic processGO:0019216680.021
regulation of secretion by cellGO:19035302080.021
single organism catabolic processGO:00447122830.021
circulatory system developmentGO:00723591340.021
peptidyl amino acid modificationGO:00181931260.021
cellular response to abiotic stimulusGO:0071214850.021
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.021
circadian rhythmGO:0007623880.021
regulation of muscle contractionGO:0006937530.021
intracellular transportGO:00469071850.020
cellular ion homeostasisGO:00068731840.020
urogenital system developmentGO:0001655780.020
tissue developmentGO:00098882520.020
regulation of intracellular signal transductionGO:19025312180.020
single organism carbohydrate metabolic processGO:00447231180.020
hormone transportGO:00099141210.020
calcium ion homeostasisGO:00550741620.020
multicellular organism growthGO:003526410.020
ensheathment of neuronsGO:0007272400.020
regulation of peptide hormone secretionGO:0090276800.020
neuron deathGO:00709971270.019
potassium ion transmembrane transportGO:0071805710.019
positive regulation of ion transportGO:0043270940.019
cellular protein localizationGO:00346131220.019
regulation of insulin secretionGO:0050796650.019
positive regulation of catabolic processGO:0009896780.019
response to inorganic substanceGO:00100353770.019
cellular amine metabolic processGO:0044106380.019
carbohydrate derivative metabolic processGO:19011353460.019
ribonucleoside metabolic processGO:00091191740.019
negative regulation of transportGO:00510511360.019
male gamete generationGO:0048232990.019
heart morphogenesisGO:000300730.019
potassium ion transportGO:0006813970.019
regulation of cell morphogenesisGO:0022604770.019
nucleotide metabolic processGO:00091172790.019
positive regulation of gene expressionGO:00106282440.019
sexual reproductionGO:00199531480.018
ribonucleotide biosynthetic processGO:0009260850.018
regulation of heart contractionGO:0008016480.018
dephosphorylationGO:0016311980.018
divalent inorganic cation homeostasisGO:00725071650.018
synaptic growth at neuromuscular junctionGO:005112410.018
positive regulation of hydrolase activityGO:0051345860.018
vesicle mediated transportGO:00161921810.018
cardiac muscle cell contractionGO:0086003100.018
carbohydrate homeostasisGO:0033500750.018
regulation of hormone secretionGO:00468831060.018
carboxylic acid metabolic processGO:00197522890.018
regulation of catalytic activityGO:00507903040.018
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.017
nucleoside phosphate metabolic processGO:00067532830.017
nucleotide biosynthetic processGO:0009165980.017
heart contractionGO:0060047570.017
cellular response to tumor necrosis factorGO:0071356460.017
response to carbohydrateGO:00097431830.017
negative regulation of transcription dna templatedGO:00458921160.017
amp metabolic processGO:004603380.017
forebrain developmentGO:0030900980.017
response to cytokineGO:00340972150.017
glycerolipid metabolic processGO:0046486670.017
negative regulation of cellular biosynthetic processGO:00313271610.017
cellular response to cytokine stimulusGO:00713451270.017
nucleoside metabolic processGO:00091161790.017
regulation of response to stressGO:00801341260.017
response to organophosphorusGO:00466831020.017
hormone secretionGO:00468791150.017
cell growthGO:00160491040.017
ribose phosphate metabolic processGO:00196932350.017
reactive oxygen species metabolic processGO:0072593370.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
regulation of peptide transportGO:0090087870.017
response to nutrientGO:00075842480.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
single organism cellular localizationGO:19025801020.016
small gtpase mediated signal transductionGO:0007264360.016
olfactory behaviorGO:004204820.016
nucleoside diphosphate metabolic processGO:0009132140.016
regulation of protein metabolic processGO:00512462890.016
nucleoside phosphate biosynthetic processGO:19012931020.016
response to decreased oxygen levelsGO:00362932370.016
regulation of cation channel activityGO:2001257230.016
chromosome segregationGO:000705920.016
positive regulation of cellular amine metabolic processGO:003324030.016
positive regulation of phosphorylationGO:00423271770.016
insulin secretionGO:0030073690.016
cellular response to mechanical stimulusGO:0071260480.016
response to transition metal nanoparticleGO:19902671220.016
regulation of growthGO:00400081050.015
positive regulation of neuron differentiationGO:00456661260.015
cytosolic calcium ion homeostasisGO:00514801400.015
positive regulation of phosphorus metabolic processGO:00105622620.015
regulation of protein phosphorylationGO:00019321830.015
response to corticosteroidGO:00319602350.015
protein transportGO:00150311320.015
positive regulation of response to stimulusGO:00485842850.015
cellular component movementGO:00069282480.015
inflammatory responseGO:00069541500.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.015
regulation of hydrolase activityGO:00513361430.015
purine ribonucleoside biosynthetic processGO:0046129210.015
negative regulation of protein metabolic processGO:00512481140.015
peptide secretionGO:0002790860.015
sensory perceptionGO:00076001010.015
regulation of calcium ion transmembrane transporter activityGO:1901019170.015
nucleoside monophosphate metabolic processGO:0009123930.015
monocarboxylic acid metabolic processGO:00327871520.015
purine ribonucleotide metabolic processGO:00091502270.015
positive regulation of cell proliferationGO:00082842490.015
rna localizationGO:000640340.014
response to peptideGO:19016522920.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.014
regulation of calcium ion transmembrane transportGO:1903169180.014
cytoplasmic transportGO:00164821150.014
regulation of cellular component biogenesisGO:0044087860.014
regulation of neurotransmitter levelsGO:0001505420.014
memoryGO:0007613540.014
regulation of protein localizationGO:0032880810.014
monocarboxylic acid transportGO:0015718520.014
purine ribonucleoside metabolic processGO:00461281680.014
positive regulation of neuron projection developmentGO:0010976990.014
amide transportGO:00428861050.014
adult locomotory behaviorGO:000834440.014
purine ribonucleotide biosynthetic processGO:0009152810.014
regulation of phosphorylationGO:00423252480.014
striated muscle contractionGO:0006941440.014
regulation of neuron apoptotic processGO:0043523830.014
cellular protein complex assemblyGO:0043623440.014
development of primary sexual characteristicsGO:00451371070.014
regulation of anatomical structure morphogenesisGO:00226031410.014
cellular response to nutrient levelsGO:0031669600.014
positive regulation of smooth muscle cell proliferationGO:0048661510.014
developmental maturationGO:0021700250.014
response to purine containing compoundGO:00140741260.014
carboxylic acid transportGO:00469421150.014
exocytosisGO:0006887600.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
regulation of chromosome segregationGO:005198310.013
regulation of calcium ion transportGO:0051924770.013
smooth muscle contractionGO:0006939370.013
single organism intracellular transportGO:19025821660.013
cell migrationGO:00164771970.013
regulation of catabolic processGO:00098941130.013
cellular protein catabolic processGO:0044257190.013
peptide transportGO:0015833970.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
establishment of protein localizationGO:00451841410.013
macromolecule catabolic processGO:0009057580.013
organic anion transportGO:00157111320.013
regulation of protein serine threonine kinase activityGO:0071900640.013
response to ethanolGO:00454711620.013
developmental process involved in reproductionGO:00030061590.013
sensory organ developmentGO:0007423740.013
positive regulation of phosphate metabolic processGO:00459372620.013
lipid transportGO:0006869610.013
cell part morphogenesisGO:00329901230.012
regulation of developmental growthGO:0048638450.012
tube developmentGO:0035295890.012
response to hexoseGO:00097461440.012
regulation of reactive oxygen species metabolic processGO:2000377260.012
cell projection morphogenesisGO:00488581230.012
negative regulation of cellular protein metabolic processGO:00322691060.012
cellular carbohydrate metabolic processGO:0044262720.012
cellular response to carbohydrate stimulusGO:0071322720.012
protein heterooligomerizationGO:0051291890.012
response to glucocorticoidGO:00513842230.012
neuromuscular synaptic transmissionGO:000727420.012
glycosyl compound metabolic processGO:19016571820.012
response to vitaminGO:00332731310.012
positive regulation of catalytic activityGO:00430851840.012
regulation of sensory perception of painGO:0051930290.012
regulation of phosphorus metabolic processGO:00511743490.012
response to activityGO:0014823730.012
embryonic axis specificationGO:000057810.012
renal system developmentGO:0072001670.012
regulation of body fluid levelsGO:0050878900.012
regulation of phosphate metabolic processGO:00192203490.012
negative regulation of multicellular organismal processGO:00512412030.012
membrane depolarization during action potentialGO:008601010.012
telencephalon developmentGO:0021537620.012
ras protein signal transductionGO:0007265290.012
actin mediated cell contractionGO:0070252120.011
cellular response to biotic stimulusGO:0071216590.011
cellular response to hexose stimulusGO:0071331650.011
peptidyl serine phosphorylationGO:0018105330.011
protein processingGO:0016485680.011
erk1 and erk2 cascadeGO:0070371480.011
spermatogenesisGO:0007283990.011
cellular response to insulin stimulusGO:0032869810.011
negative regulation of secretionGO:0051048820.011
axon developmentGO:0061564960.011
response to external biotic stimulusGO:00432072210.011
male mating behaviorGO:006017930.011
ribonucleoside monophosphate metabolic processGO:0009161880.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
formation of primary germ layerGO:000170410.011
cellular response to extracellular stimulusGO:0031668730.011
kidney developmentGO:0001822670.011
regulation of intracellular transportGO:0032386650.011
negative regulation of rna biosynthetic processGO:19026791180.011
response to woundingGO:00096112540.011
cellular response to molecule of bacterial originGO:0071219560.011
response to growth factorGO:00708481890.011
cellular glucose homeostasisGO:0001678660.011
cellular response to glucose stimulusGO:0071333650.011
vesicle fusionGO:0006906140.011
wound healingGO:00420601220.011
negative regulation of intracellular signal transductionGO:1902532380.011
positive regulation of locomotionGO:00400171020.011
protein catabolic processGO:0030163300.011
positive regulation of cell communicationGO:00106472710.011
locomotor rhythmGO:004547510.011
response to reactive oxygen speciesGO:00003021200.011
regulation of neuron deathGO:19012141150.011
locomotionGO:00400112370.011
response to acid chemicalGO:00011012220.011
negative regulation of synaptic transmissionGO:0050805290.010
regulation of proteolysisGO:0030162660.010
aromatic compound catabolic processGO:00194391680.010
regulation of cellular component movementGO:00512701500.010
membrane organizationGO:0061024940.010
regulation of mapk cascadeGO:00434081160.010
regulation of response to external stimulusGO:00321011060.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
response to peptide hormoneGO:00434342780.010
glucose metabolic processGO:0006006520.010
regulation of sensory perceptionGO:0051931290.010
cellular response to steroid hormone stimulusGO:0071383930.010
regulation of vasoconstrictionGO:0019229440.010
cellular response to growth factor stimulusGO:00713631620.010
response to retinoic acidGO:0032526630.010
regulation of cell cycle processGO:0010564310.010
positive regulation of mapk cascadeGO:0043410920.010
cellular macromolecular complex assemblyGO:0034622580.010

Scn1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.136
carbohydrate metabolic disorderDOID:297800.136
disease of metabolismDOID:001466700.136
nervous system diseaseDOID:86300.067
disease of anatomical entityDOID:700.067
long qt syndromeDOID:284300.023
central nervous system diseaseDOID:33100.016
acquired metabolic diseaseDOID:006015800.015
musculoskeletal system diseaseDOID:1700.014
disease of cellular proliferationDOID:1456600.013
neuropathyDOID:87000.012
neuromuscular diseaseDOID:44000.012
glucose metabolism diseaseDOID:419400.011
carbohydrate metabolism diseaseDOID:005001300.011
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
myopathyDOID:42300.011