Rattus norvegicus

41 known processes

Scn1a

sodium channel, voltage-gated, type I, alpha

Scn1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein complex assemblyGO:00064612630.208
cellular component biogenesisGO:00440853680.179
positive regulation of multicellular organismal processGO:00512403870.170
Rat
macromolecular complex subunit organizationGO:00439333390.156
cell cell signalingGO:00072673350.148
protein complex biogenesisGO:00702712630.134
protein complex subunit organizationGO:00718223020.111
response to inorganic substanceGO:00100353770.111
cellular response to endogenous stimulusGO:00714953770.110
anatomical structure morphogenesisGO:00096532980.103
Rat
reproductive processGO:00224143720.099
cellular component assemblyGO:00226073600.096
neuron differentiationGO:00301823680.093
response to estrogenGO:00436272320.092
neuron developmentGO:00486662860.090
cation transportGO:00068123820.089
response to metal ionGO:00100382530.088
cation transmembrane transportGO:00986552630.087
macromolecular complex assemblyGO:00650032730.084
cell projection organizationGO:00300303020.083
transmembrane transportGO:00550854120.082
cellular homeostasisGO:00197252520.080
ion transmembrane transportGO:00342203650.075
regulation of cell developmentGO:00602842630.075
synaptic transmissionGO:00072682350.073
response to extracellular stimulusGO:00099913800.065
response to nutrient levelsGO:00316673700.065
choline transportGO:001587140.062
Rat
negative regulation of signalingGO:00230571570.060
regulation of neuron differentiationGO:00456642080.060
regulation of signal transductionGO:00099663180.059
response to nutrientGO:00075842480.057
protein oligomerizationGO:00512591910.057
positive regulation of biosynthetic processGO:00098913190.055
response to peptideGO:19016522920.054
multi organism reproductive processGO:00447032620.054
ion homeostasisGO:00508012120.053
positive regulation of cell proliferationGO:00082842490.051
Rat
neurological system processGO:00508772190.050
positive regulation of nucleobase containing compound metabolic processGO:00459353190.050
nitrogen compound transportGO:00717052290.050
Rat
regulation of locomotionGO:00400121480.050
response to oxidative stressGO:00069791860.049
regulation of nervous system developmentGO:00519602640.049
oxoacid metabolic processGO:00434362900.049
cellular cation homeostasisGO:00300031800.049
neuron projection developmentGO:00311752730.049
regulation of cell proliferationGO:00421273590.049
Rat
regulation of transcription dna templatedGO:00063553740.048
multicellular organism reproductionGO:00325042330.048
carboxylic acid metabolic processGO:00197522890.048
response to peptide hormoneGO:00434342780.048
cellular response to stressGO:00335542690.048
organic acid metabolic processGO:00060822920.047
cell projection morphogenesisGO:00488581230.047
regulation of cellular localizationGO:00603412630.046
reproductionGO:00000032450.046
macromolecule localizationGO:00330362520.046
cellular chemical homeostasisGO:00550822470.046
response to hypoxiaGO:00016662310.046
organelle organizationGO:00069962660.045
neuron apoptotic processGO:0051402880.045
regulation of molecular functionGO:00650093980.045
negative regulation of cell communicationGO:00106481580.044
intracellular signal transductionGO:00355563140.044
response to carbohydrateGO:00097431830.043
head developmentGO:00603222470.043
Rat
regulation of phosphorus metabolic processGO:00511743490.043
response to toxic substanceGO:00096361330.043
positive regulation of neuron projection developmentGO:0010976990.042
positive regulation of developmental processGO:00510942830.042
positive regulation of nervous system developmentGO:00519621780.042
regulation of multicellular organismal developmentGO:20000263760.042
regulation of phosphate metabolic processGO:00192203490.042
multi multicellular organism processGO:00447061380.042
action potentialGO:0001508540.041
response to estradiolGO:00323551640.041
regulation of cellular component movementGO:00512701500.041
cellular response to oxygen containing compoundGO:19017013860.040
rna biosynthetic processGO:00327743800.040
positive regulation of neurogenesisGO:00507691650.040
cellular response to organonitrogen compoundGO:00714171970.040
positive regulation of cell developmentGO:00107201760.040
regulation of cell projection organizationGO:00313441750.039
regulation of catalytic activityGO:00507903040.039
positive regulation of cell projection organizationGO:00313461110.039
homeostatic processGO:00425923310.039
response to oxygen levelsGO:00704822650.038
amino acid transportGO:0006865700.038
rhythmic processGO:00485111560.038
positive regulation of neuron differentiationGO:00456661260.038
central nervous system developmentGO:00074173110.038
Rat
response to transition metal nanoparticleGO:19902671220.038
cell motilityGO:00488702020.037
regulation of cellular ketone metabolic processGO:0010565270.037
single organism organelle organizationGO:19025891800.037
programmed cell deathGO:00125013920.037
response to glucocorticoidGO:00513842230.037
transcription dna templatedGO:00063513770.037
anion transmembrane transportGO:0098656770.036
positive regulation of cellular component organizationGO:00511302000.036
circulatory system processGO:00030131830.036
Rat
signal releaseGO:00230611450.035
chemical homeostasisGO:00488782920.035
positive regulation of molecular functionGO:00440932300.035
positive regulation of cell differentiationGO:00455972170.035
positive regulation of nitrogen compound metabolic processGO:00511733340.035
positive regulation of cellular biosynthetic processGO:00313282950.035
regulation of cell differentiationGO:00455953200.034
transcription from rna polymerase ii promoterGO:00063662520.034
behaviorGO:00076102050.034
regulation of cellular component organizationGO:00511283680.034
cellular amino acid metabolic processGO:00065201070.033
cellular amine metabolic processGO:0044106380.033
response to purine containing compoundGO:00140741260.033
single organism reproductive processGO:00447022970.033
cellular metal ion homeostasisGO:00068751720.032
cellular response to nitrogen compoundGO:19016992100.032
response to decreased oxygen levelsGO:00362932370.032
regulation of anatomical structure sizeGO:00900661350.032
positive regulation of transcription dna templatedGO:00458931970.032
cellular response to peptide hormone stimulusGO:00713751200.032
cellular response to hormone stimulusGO:00328702470.032
positive regulation of gene expressionGO:00106282440.032
organophosphate metabolic processGO:00196373700.031
amine metabolic processGO:0009308380.031
cellular calcium ion homeostasisGO:00068741600.031
neuronal action potentialGO:0019228350.031
locomotionGO:00400112370.030
carbohydrate derivative metabolic processGO:19011353460.030
brain developmentGO:00074202470.030
Rat
regulation of apoptotic processGO:00429813350.030
neuron deathGO:00709971270.030
axon developmentGO:0061564960.030
multicellular organismal signalingGO:0035637440.030
multicellular organismal reproductive processGO:00486092330.029
regulation of neurogenesisGO:00507672470.029
regulation of secretion by cellGO:19035302080.029
negative regulation of developmental processGO:00510931250.029
secretionGO:00469033070.029
positive regulation of phosphorus metabolic processGO:00105622620.029
positive regulation of catalytic activityGO:00430851840.029
metal ion transportGO:00300012890.028
regulation of rna biosynthetic processGO:20011413810.028
organic anion transportGO:00157111320.028
negative regulation of response to stimulusGO:00485851550.028
positive regulation of cell migrationGO:0030335960.028
regulation of nucleic acid templated transcriptionGO:19035063800.027
signal transduction by phosphorylationGO:00230141440.027
regulation of neuron projection developmentGO:00109751610.027
ribose phosphate metabolic processGO:00196932350.027
neuron projection morphogenesisGO:00488121220.027
negative regulation of cell proliferationGO:00082851190.027
regulation of cellular amine metabolic processGO:003323880.027
response to acid chemicalGO:00011012220.027
regulation of neuron deathGO:19012141150.027
regulation of ion transportGO:00432692450.026
response to biotic stimulusGO:00096072260.026
nucleotide metabolic processGO:00091172790.026
response to corticosteroidGO:00319602350.026
cell migrationGO:00164771970.026
negative regulation of multicellular organismal processGO:00512412030.026
divalent inorganic cation homeostasisGO:00725071650.026
response to reactive oxygen speciesGO:00003021200.026
apoptotic processGO:00069153810.026
rna metabolic processGO:00160704060.026
regulation of phosphorylationGO:00423252480.025
response to alkaloidGO:00432791320.025
positive regulation of nucleic acid templated transcriptionGO:19035081970.025
heart morphogenesisGO:000300730.025
response to woundingGO:00096112540.025
regulation of anatomical structure morphogenesisGO:00226031410.025
positive regulation of signalingGO:00230562700.025
nucleoside phosphate metabolic processGO:00067532830.025
response to bacteriumGO:00096172000.025
agingGO:00075682410.024
purine ribonucleotide metabolic processGO:00091502270.024
response to ethanolGO:00454711620.024
regulation of response to stressGO:00801341260.024
cellular ion homeostasisGO:00068731840.024
carboxylic acid transportGO:00469421150.024
nucleic acid templated transcriptionGO:00976593790.024
regulation of cellular amino acid metabolic processGO:000652120.024
positive regulation of response to stimulusGO:00485842850.024
cellular ketone metabolic processGO:0042180510.023
positive regulation of rna metabolic processGO:00512542030.023
response to campGO:0051591910.023
regulation of purine nucleotide metabolic processGO:19005421150.023
regulation of behaviorGO:0050795610.023
negative regulation of metabolic processGO:00098923310.023
learningGO:0007612330.023
regulation of programmed cell deathGO:00430673410.023
regulation of membrane potentialGO:00423911100.022
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
synaptic vesicle primingGO:001608240.022
response to monosaccharideGO:00342841590.022
regulation of body fluid levelsGO:0050878900.022
regulation of hormone levelsGO:00108171870.022
cellular divalent inorganic cation homeostasisGO:00725031620.022
positive regulation of phosphate metabolic processGO:00459372620.022
organic hydroxy compound transportGO:0015850770.022
Rat
learning or memoryGO:0007611900.022
regulation of cell morphogenesis involved in differentiationGO:0010769720.022
single organism biosynthetic processGO:00447113420.022
regulation of intracellular signal transductionGO:19025312180.022
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.022
nucleobase containing small molecule metabolic processGO:00550863160.021
cell part morphogenesisGO:00329901230.021
cardiac chamber developmentGO:000320510.021
response to ketoneGO:19016541820.021
negative regulation of cell deathGO:00605482290.021
calcium ion homeostasisGO:00550741620.021
anion transportGO:00068201780.021
response to insulinGO:00328681330.021
regulation of catabolic processGO:00098941130.021
cellular response to lipidGO:00713962010.021
glycosyl compound catabolic processGO:19016581260.021
defense responseGO:00069521940.020
cation homeostasisGO:00550801950.020
secretion by cellGO:00329402480.020
inflammatory responseGO:00069541500.020
small gtpase mediated signal transductionGO:0007264360.020
positive regulation of rna biosynthetic processGO:19026801970.020
response to growth factorGO:00708481890.020
catabolic processGO:00090563510.020
purine containing compound metabolic processGO:00725212530.019
response to radiationGO:00093141370.019
negative regulation of gene expressionGO:00106291990.019
ras protein signal transductionGO:0007265290.019
negative regulation of neuron differentiationGO:0045665620.019
bmp signaling pathwayGO:003050940.019
regulation of system processGO:00440572080.019
Rat
purine nucleotide metabolic processGO:00061632290.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
adult locomotory behaviorGO:000834440.019
immune system processGO:00023762040.019
lipid metabolic processGO:00066292830.019
metal ion homeostasisGO:00550651860.019
synaptic transmission glutamatergicGO:0035249330.019
cellular component morphogenesisGO:00329891550.019
positive regulation of cellular amine metabolic processGO:003324030.019
transmission of nerve impulseGO:0019226420.019
organophosphate biosynthetic processGO:00904071430.019
ribonucleoside metabolic processGO:00091191740.018
protein homooligomerizationGO:0051260910.018
neurotransmitter uptakeGO:000150430.018
positive regulation of cellular protein metabolic processGO:00322701670.018
purine nucleoside metabolic processGO:00422781690.018
cell morphogenesis involved in neuron differentiationGO:00486671060.018
circulatory system developmentGO:00723591340.018
positive regulation of transportGO:00510502450.018
regulation of rna metabolic processGO:00512523910.018
negative regulation of programmed cell deathGO:00430691830.018
cell morphogenesisGO:00009021420.018
organic substance catabolic processGO:19015753160.017
female pregnancyGO:00075651220.017
hormone transportGO:00099141210.017
response to glucoseGO:00097491360.017
response to mechanical stimulusGO:00096121340.017
cellular protein localizationGO:00346131220.017
fatty acid transmembrane transportGO:190200130.017
positive regulation of protein modification processGO:00314011420.017
cellular lipid metabolic processGO:00442552080.017
embryonic skeletal system developmentGO:004870630.017
regenerationGO:00310991630.017
glycosyl compound metabolic processGO:19016571820.017
positive regulation of cell deathGO:00109421840.017
negative regulation of cell developmentGO:0010721820.017
cardiovascular system developmentGO:00723581340.017
protein phosphorylationGO:00064683450.017
synaptic growth at neuromuscular junctionGO:005112410.017
regulation of response to woundingGO:1903034690.017
response to fatty acidGO:0070542650.017
cellular response to organic cyclic compoundGO:00714072020.017
potassium ion transportGO:0006813970.016
Rat
regulation of synaptic transmissionGO:00508041410.016
peptide transportGO:0015833970.016
response to nicotineGO:0035094510.016
gliogenesisGO:0042063930.016
regulation of neuron apoptotic processGO:0043523830.016
intracellular transportGO:00469071850.016
cellular response to peptideGO:19016531330.016
muscle contractionGO:0006936880.016
response to vitaminGO:00332731310.016
regulation of secretionGO:00510462240.016
regulation of cell morphogenesisGO:0022604770.016
neuron neuron synaptic transmissionGO:0007270600.016
regulation of protein metabolic processGO:00512462890.016
sex differentiationGO:00075481130.016
positive regulation of apoptotic processGO:00430651540.016
cellular response to growth factor stimulusGO:00713631620.016
localization of cellGO:00516742020.015
positive regulation of macromolecule biosynthetic processGO:00105572470.015
positive regulation of protein metabolic processGO:00512471780.015
regulation of neurotransmitter levelsGO:0001505420.015
growthGO:00400071650.015
sexual reproductionGO:00199531480.015
positive regulation of protein phosphorylationGO:00019341350.015
cellular response to insulin stimulusGO:0032869810.015
blood circulationGO:00080151830.015
Rat
regulation of protein modification processGO:00313991940.015
hormone metabolic processGO:0042445690.015
amino acid transmembrane transportGO:0003333330.015
monoamine transportGO:0015844430.015
organophosphate catabolic processGO:00464341480.015
regulation of canonical wnt signaling pathwayGO:006082840.015
organic acid transportGO:00158491160.015
organonitrogen compound catabolic processGO:19015651790.015
regulation of homeostatic processGO:00328441010.015
positive regulation of phosphorylationGO:00423271770.015
actin filament based processGO:0030029860.015
response to lipopolysaccharideGO:00324961910.015
regulation of exocytosisGO:0017157370.015
positive regulation of defense responseGO:0031349370.014
carbohydrate derivative biosynthetic processGO:19011371240.014
response to molecule of bacterial originGO:00022371940.014
regulation of cellular catabolic processGO:00313291010.014
response to organophosphorusGO:00466831020.014
axonogenesisGO:0007409710.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
cellular protein complex assemblyGO:0043623440.014
cell type specific apoptotic processGO:00972851340.014
ribonucleotide metabolic processGO:00092592310.014
nucleoside metabolic processGO:00091161790.014
purine ribonucleoside metabolic processGO:00461281680.014
negative regulation of apoptotic processGO:00430661810.014
response to ammonium ionGO:0060359710.014
cellular response to abiotic stimulusGO:0071214850.014
nucleoside triphosphate metabolic processGO:00091411440.014
regulation of proteasomal protein catabolic processGO:006113640.014
regulation of cellular protein metabolic processGO:00322682670.014
negative regulation of cellular metabolic processGO:00313242810.014
muscle system processGO:00030121150.014
regulation of response to external stimulusGO:00321011060.014
single organism behaviorGO:00447081300.014
vesicle mediated transportGO:00161921810.014
glucose homeostasisGO:0042593750.014
amide transportGO:00428861050.013
regulation of nucleotide metabolic processGO:00061401170.013
positive regulation of lipid catabolic processGO:005099640.013
regulation of growthGO:00400081050.013
guanosine containing compound metabolic processGO:1901068740.013
protein localizationGO:00081041910.013
cellular catabolic processGO:00442482950.013
monovalent inorganic cation transportGO:00156721720.013
response to cocaineGO:0042220390.013
negative regulation of neurogenesisGO:0050768780.013
cellular nitrogen compound catabolic processGO:00442701630.013
establishment of protein localizationGO:00451841410.013
sulfur compound metabolic processGO:0006790700.013
response to external biotic stimulusGO:00432072210.013
regulation of protein phosphorylationGO:00019321830.013
carbohydrate metabolic processGO:00059751300.013
aromatic compound catabolic processGO:00194391680.013
smooth muscle cell migrationGO:0014909360.013
response to cytokineGO:00340972150.013
cellular response to cytokine stimulusGO:00713451270.013
forebrain developmentGO:0030900980.013
Rat
heterocycle catabolic processGO:00467001670.013
response to cgmpGO:007030530.013
positive regulation of cell communicationGO:00106472710.013
schwann cell migrationGO:003613520.013
regulation of tube sizeGO:0035150890.013
g protein coupled receptor signaling pathwayGO:00071862420.013
regulation of dendrite developmentGO:0050773590.013
response to other organismGO:00517072200.013
mesoderm developmentGO:000749820.013
carbohydrate homeostasisGO:0033500750.013
chemosensory behaviorGO:000763520.013
microtubule organizing center organizationGO:003102310.013
actin cytoskeleton organizationGO:0030036730.013
hormone secretionGO:00468791150.013
response to hexoseGO:00097461440.013
ribonucleoside triphosphate catabolic processGO:00092031220.013
anatomical structure formation involved in morphogenesisGO:0048646830.013
developmental growthGO:00485891000.013
regulation of bmp signaling pathwayGO:003051020.013
catecholamine transportGO:0051937370.013
regulation of gtpase activityGO:0043087570.013
negative regulation of cellular component organizationGO:0051129830.012
reproductive structure developmentGO:00486081280.012
positive regulation of cellular component movementGO:00512721020.012
regulation of cell motilityGO:20001451310.012
regulation of blood pressureGO:0008217830.012
cell morphogenesis involved in differentiationGO:00009041190.012
single organism catabolic processGO:00447122830.012
carboxylic acid catabolic processGO:0046395490.012
inorganic ion transmembrane transportGO:00986602290.012
positive regulation of transferase activityGO:0051347810.012
cell adhesionGO:00071551100.012
cytoskeleton organizationGO:00070101110.012
regulation of cellular response to stressGO:0080135490.012
male gamete generationGO:0048232990.012
peptide secretionGO:0002790860.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
muscle cell proliferationGO:0033002840.012
small molecule catabolic processGO:0044282590.012
spindle organizationGO:000705120.012
carbohydrate derivative catabolic processGO:19011361470.012
positive regulation of neuron apoptotic processGO:0043525330.012
ribonucleotide catabolic processGO:00092611360.012
purine nucleoside catabolic processGO:00061521240.012
regulation of hydrolase activityGO:00513361430.012
metanephric s shaped body morphogenesisGO:007228420.012
cellular component movementGO:00069282480.012
nucleobase containing compound catabolic processGO:00346551520.012
monocarboxylic acid transportGO:0015718520.012
chromosome segregationGO:000705920.012
heart developmentGO:0007507720.012
negative regulation of synaptic transmissionGO:0050805290.012
organonitrogen compound biosynthetic processGO:19015661670.011
cardiac ventricle developmentGO:000323110.011
cytosolic calcium ion homeostasisGO:00514801400.011
regulation of mapk cascadeGO:00434081160.011
modified amino acid transportGO:0072337120.011
response to calcium ionGO:0051592590.011
olfactory behaviorGO:004204820.011
positive regulation of mapk cascadeGO:0043410920.011
cellular macromolecular complex assemblyGO:0034622580.011
regulation of cell migrationGO:00303341280.011
protein tetramerizationGO:0051262380.011
smooth muscle cell proliferationGO:0048659770.011
response to sucroseGO:0009744100.011
positive regulation of cellular catabolic processGO:0031331710.011
response to increased oxygen levelsGO:0036296450.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
protein heterooligomerizationGO:0051291890.011
gtp metabolic processGO:0046039720.011
cell fate determinationGO:000170920.011
negative regulation of transportGO:00510511360.011
regulation of mesenchymal cell proliferationGO:001046440.011
cellular response to external stimulusGO:00714961180.011
lipid biosynthetic processGO:00086101280.011
regulation of hormone secretionGO:00468831060.011
nucleoside catabolic processGO:00091641260.011
organic cyclic compound catabolic processGO:19013611750.011
positive regulation of synaptic transmissionGO:0050806620.011
spermatogenesisGO:0007283990.010
dna metabolic processGO:0006259960.010
glutamate receptor signaling pathwayGO:0007215430.010
positive regulation of secretion by cellGO:19035321280.010
lipid transportGO:0006869610.010
cellular response to cgmpGO:007132120.010
ribonucleoside catabolic processGO:00424541260.010
dephosphorylationGO:0016311980.010
neurotransmitter transportGO:0006836420.010
secretion by tissueGO:0032941370.010
negative regulation of nervous system developmentGO:0051961790.010
reproductive system developmentGO:00614581280.010
defense response to gram negative bacteriumGO:005082930.010
neural crest cell developmentGO:001403220.010
membrane organizationGO:0061024940.010
alcohol metabolic processGO:0006066770.010
purine ribonucleoside catabolic processGO:00461301240.010
vascular process in circulatory systemGO:0003018960.010
organic hydroxy compound metabolic processGO:19016151150.010
proteolysisGO:00065081750.010

Scn1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
Human
nervous system diseaseDOID:86300.038
Human
musculoskeletal system diseaseDOID:1700.021
central nervous system diseaseDOID:33100.015
Human
sensory system diseaseDOID:005015500.012
disease of metabolismDOID:001466700.010