Rattus norvegicus

36 known processes

Hadha

hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit

(Aliases: RGD1560655,MGC105338)

Hadha biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
fatty acid oxidationGO:0019395290.889
fatty acid metabolic processGO:0006631990.684
monocarboxylic acid metabolic processGO:00327871520.531
lipid oxidationGO:0034440300.493
oxoacid metabolic processGO:00434362900.493
carboxylic acid metabolic processGO:00197522890.468
cellular lipid metabolic processGO:00442552080.445
long chain fatty acid metabolic processGO:0001676320.438
lipid metabolic processGO:00066292830.423
organic acid metabolic processGO:00060822920.363
monocarboxylic acid catabolic processGO:0072329280.281
cellular lipid catabolic processGO:0044242370.241
oxidation reduction processGO:00551143040.226
small molecule catabolic processGO:0044282590.203
lipid catabolic processGO:0016042460.203
cellular catabolic processGO:00442482950.201
carboxylic acid catabolic processGO:0046395490.199
fatty acid catabolic processGO:0009062260.196
catabolic processGO:00090563510.193
lipid modificationGO:0030258520.172
programmed cell deathGO:00125013920.142
response to nutrientGO:00075842480.141
fatty acid beta oxidationGO:0006635220.129
thioester metabolic processGO:0035383280.127
apoptotic processGO:00069153810.121
regulation of programmed cell deathGO:00430673410.118
response to oxygen levelsGO:00704822650.117
acetyl coa metabolic processGO:0006084170.117
single organism biosynthetic processGO:00447113420.115
response to nutrient levelsGO:00316673700.113
single organism catabolic processGO:00447122830.111
sulfur compound metabolic processGO:0006790700.109
cofactor metabolic processGO:0051186950.100
regulation of apoptotic processGO:00429813350.098
acyl coa metabolic processGO:0006637280.097
cellular ketone metabolic processGO:0042180510.091
organic anion transportGO:00157111320.089
organic acid catabolic processGO:0016054490.086
carboxylic acid transportGO:00469421150.085
negative regulation of apoptotic processGO:00430661810.083
response to extracellular stimulusGO:00099913800.079
regulation of cellular localizationGO:00603412630.076
organic acid transportGO:00158491160.073
anion transportGO:00068201780.070
single organism intracellular transportGO:19025821660.069
organic substance catabolic processGO:19015753160.065
regulation of cellular ketone metabolic processGO:0010565270.062
reproductive processGO:00224143720.061
negative regulation of programmed cell deathGO:00430691830.060
organelle organizationGO:00069962660.059
antral ovarian follicle growthGO:000154730.056
cellular component assemblyGO:00226073600.054
protein oligomerizationGO:00512591910.052
cellular response to stressGO:00335542690.052
alcohol metabolic processGO:0006066770.051
negative regulation of cell deathGO:00605482290.051
small molecule biosynthetic processGO:00442831240.051
protein phosphorylationGO:00064683450.050
response to hypoxiaGO:00016662310.049
response to decreased oxygen levelsGO:00362932370.047
cellular response to oxygen containing compoundGO:19017013860.047
regulation of lipid metabolic processGO:0019216680.045
regulation of signal transductionGO:00099663180.045
carboxylic acid biosynthetic processGO:0046394830.044
homeostatic processGO:00425923310.044
protein complex biogenesisGO:00702712630.043
coenzyme metabolic processGO:0006732860.043
protein complex subunit organizationGO:00718223020.043
nitrogen compound transportGO:00717052290.042
cellular amine metabolic processGO:0044106380.042
amide transportGO:00428861050.041
glycerolipid metabolic processGO:0046486670.041
response to acid chemicalGO:00011012220.041
ion transmembrane transportGO:00342203650.041
regulation of cellular component organizationGO:00511283680.040
cellular response to peptideGO:19016531330.038
monocarboxylic acid transportGO:0015718520.038
response to metal ionGO:00100382530.037
cellular response to endogenous stimulusGO:00714953770.037
positive regulation of multicellular organismal processGO:00512403870.037
lipid biosynthetic processGO:00086101280.037
signal releaseGO:00230611450.036
organic hydroxy compound metabolic processGO:19016151150.036
fatty acid biosynthetic processGO:0006633330.036
gland developmentGO:00487321550.035
cellular response to lipidGO:00713962010.035
macromolecular complex assemblyGO:00650032730.035
intracellular transportGO:00469071850.035
protein homooligomerizationGO:0051260910.035
regulation of hormone levelsGO:00108171870.035
protein complex assemblyGO:00064612630.035
acetate ester biosynthetic processGO:190062020.034
response to ethanolGO:00454711620.034
cellular component biogenesisGO:00440853680.033
regulation of phosphorylationGO:00423252480.033
multicellular organism reproductionGO:00325042330.033
neutral lipid metabolic processGO:0006638210.033
positive regulation of lipid catabolic processGO:005099640.032
regulation of organelle organizationGO:0033043800.032
behaviorGO:00076102050.032
amine metabolic processGO:0009308380.032
response to peptideGO:19016522920.032
positive regulation of cell differentiationGO:00455972170.031
secretion by cellGO:00329402480.031
neurological system processGO:00508772190.031
macromolecule localizationGO:00330362520.030
response to peptide hormoneGO:00434342780.030
carbohydrate metabolic processGO:00059751300.030
negative regulation of metabolic processGO:00098923310.030
positive regulation of cell communicationGO:00106472710.030
positive regulation of fatty acid beta oxidationGO:003200040.030
positive regulation of cellular amino acid metabolic processGO:004576410.030
lipid localizationGO:0010876620.029
organic acid biosynthetic processGO:0016053830.029
multicellular organismal reproductive processGO:00486092330.029
lipid transportGO:0006869610.028
response to inorganic substanceGO:00100353770.028
anion transmembrane transportGO:0098656770.028
cell projection organizationGO:00300303020.028
regulation of secretionGO:00510462240.028
growthGO:00400071650.027
regulation of multicellular organismal developmentGO:20000263760.027
macromolecular complex subunit organizationGO:00439333390.027
positive regulation of cellular biosynthetic processGO:00313282950.027
secretionGO:00469033070.027
reproductionGO:00000032450.027
positive regulation of fatty acid oxidationGO:004632160.027
positive regulation of signal transductionGO:00099671750.027
neuron projection developmentGO:00311752730.027
protein transportGO:00150311320.026
intracellular signal transductionGO:00355563140.026
regulation of phosphate metabolic processGO:00192203490.026
hormone transportGO:00099141210.026
regulation of protein modification processGO:00313991940.025
spindle organizationGO:000705120.025
negative regulation of transportGO:00510511360.025
transmembrane transportGO:00550854120.025
regulation of phosphorus metabolic processGO:00511743490.025
carnitine metabolic processGO:000943730.024
positive regulation of protein metabolic processGO:00512471780.024
triglyceride metabolic processGO:0006641210.024
regulation of cellular amine metabolic processGO:003323880.024
regulation of cell proliferationGO:00421273590.024
regulation of protein phosphorylationGO:00019321830.024
cellular response to hormone stimulusGO:00328702470.024
negative regulation of signalingGO:00230571570.024
response to biotic stimulusGO:00096072260.023
cell cycleGO:00070491010.023
cell morphogenesis involved in neuron differentiationGO:00486671060.023
regulation of cellular amino acid metabolic processGO:000652120.023
regulation of molecular functionGO:00650093980.023
neuron developmentGO:00486662860.023
acylglycerol metabolic processGO:0006639210.023
peptide transportGO:0015833970.022
organophosphate biosynthetic processGO:00904071430.022
cellular component morphogenesisGO:00329891550.022
peptide secretionGO:0002790860.022
regulation of cellular protein metabolic processGO:00322682670.022
neuron differentiationGO:00301823680.022
regulation of neurogenesisGO:00507672470.022
regulation of fatty acid metabolic processGO:0019217180.022
anatomical structure morphogenesisGO:00096532980.022
amino acid betaine metabolic processGO:000657730.021
response to external biotic stimulusGO:00432072210.021
positive regulation of biosynthetic processGO:00098913190.021
negative regulation of response to stimulusGO:00485851550.021
immune system processGO:00023762040.021
cellular response to external stimulusGO:00714961180.021
regulation of intracellular signal transductionGO:19025312180.021
positive regulation of molecular functionGO:00440932300.021
response to oxidative stressGO:00069791860.021
steroid metabolic processGO:0008202730.021
tissue developmentGO:00098882520.021
response to estrogenGO:00436272320.020
regulation of secretion by cellGO:19035302080.020
positive regulation of phosphorylationGO:00423271770.020
response to monosaccharideGO:00342841590.020
agingGO:00075682410.020
positive regulation of protein phosphorylationGO:00019341350.020
apoptotic signaling pathwayGO:0097190270.020
organophosphate metabolic processGO:00196373700.020
regulation of cell developmentGO:00602842630.020
negative regulation of cell communicationGO:00106481580.020
regulation of protein metabolic processGO:00512462890.020
positive regulation of response to stimulusGO:00485842850.020
developmental process involved in reproductionGO:00030061590.020
regulation of rna biosynthetic processGO:20011413810.019
response to woundingGO:00096112540.019
response to fatty acidGO:0070542650.019
gonad developmentGO:00084061040.019
hexose metabolic processGO:0019318580.019
regulation of neuron differentiationGO:00456642080.019
regulation of fatty acid oxidationGO:0046320100.019
positive regulation of developmental processGO:00510942830.019
regulation of cell differentiationGO:00455953200.019
chemical homeostasisGO:00488782920.019
regulation of peptide hormone secretionGO:0090276800.019
single organism membrane organizationGO:0044802740.019
regulation of intracellular transportGO:0032386650.019
reproductive system developmentGO:00614581280.019
protein localizationGO:00081041910.018
response to molecule of bacterial originGO:00022371940.018
positive regulation of phosphorus metabolic processGO:00105622620.018
rna metabolic processGO:00160704060.018
cell cell signalingGO:00072673350.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
single organism nuclear importGO:1902593350.018
cellular response to organonitrogen compoundGO:00714171970.018
long chain fatty acid transportGO:0015909140.018
regulation of peptide transportGO:0090087870.018
mitotic spindle organizationGO:000705220.018
positive regulation of signalingGO:00230562700.018
central nervous system developmentGO:00074173110.017
cellular amino acid metabolic processGO:00065201070.017
single organism behaviorGO:00447081300.017
response to other organismGO:00517072200.017
regulation of fatty acid beta oxidationGO:003199880.017
negative regulation of multicellular organismal processGO:00512412030.017
positive regulation of cellular amine metabolic processGO:003324030.017
cellular response to organic cyclic compoundGO:00714072020.017
positive regulation of cellular protein metabolic processGO:00322701670.017
cytoplasmic transportGO:00164821150.017
organonitrogen compound biosynthetic processGO:19015661670.017
response to carbohydrateGO:00097431830.017
regulation of cellular catabolic processGO:00313291010.017
protein importGO:0017038370.017
regulation of hormone secretionGO:00468831060.017
b cell differentiationGO:003018320.017
negative regulation of macromolecule metabolic processGO:00106052600.017
negative regulation of cellular metabolic processGO:00313242810.016
transcription dna templatedGO:00063513770.016
cellular response to nutrient levelsGO:0031669600.016
regulation of nervous system developmentGO:00519602640.016
positive regulation of phosphate metabolic processGO:00459372620.016
response to bacteriumGO:00096172000.016
regulation of catalytic activityGO:00507903040.016
single organism reproductive processGO:00447022970.016
multi organism reproductive processGO:00447032620.016
regulation of nucleic acid templated transcriptionGO:19035063800.015
positive regulation of intracellular signal transductionGO:19025331380.015
chromosome segregationGO:000705920.015
hormone secretionGO:00468791150.015
positive regulation of cell developmentGO:00107201760.015
regulation of establishment of protein localizationGO:0070201690.015
establishment of protein localizationGO:00451841410.015
cellular response to nitrogen compoundGO:19016992100.015
hepaticobiliary system developmentGO:0061008900.015
monosaccharide metabolic processGO:0005996610.015
positive regulation of nervous system developmentGO:00519621780.014
reproductive structure developmentGO:00486081280.014
regulation of catabolic processGO:00098941130.014
positive regulation of cell proliferationGO:00082842490.014
response to glucocorticoidGO:00513842230.014
single organism carbohydrate metabolic processGO:00447231180.014
response to reactive oxygen speciesGO:00003021200.014
nucleocytoplasmic transportGO:0006913480.014
regulation of peptide secretionGO:0002791820.014
cell morphogenesis involved in differentiationGO:00009041190.014
cell type specific apoptotic processGO:00972851340.014
nucleic acid templated transcriptionGO:00976593790.014
brain developmentGO:00074202470.014
response to corticosteroidGO:00319602350.014
regulation of anatomical structure morphogenesisGO:00226031410.014
nuclear transportGO:0051169490.014
positive regulation of protein modification processGO:00314011420.014
negative regulation of biosynthetic processGO:00098901680.014
small gtpase mediated signal transductionGO:0007264360.014
protein import into nucleusGO:0006606350.014
cellular response to extracellular stimulusGO:0031668730.014
positive regulation of nitrogen compound metabolic processGO:00511733340.014
cellular response to peptide hormone stimulusGO:00713751200.013
cellular macromolecule localizationGO:00707271220.013
negative regulation of molecular functionGO:00440921330.013
circulatory system processGO:00030131830.013
protein targeting to nucleusGO:0044744350.013
response to insulinGO:00328681330.013
cognitionGO:0050890920.013
cation homeostasisGO:00550801950.013
negative regulation of cellular component organizationGO:0051129830.013
regulation of cell projection organizationGO:00313441750.013
regulation of insulin secretionGO:0050796650.013
transcription from rna polymerase ii promoterGO:00063662520.013
sensory perception of painGO:0019233730.013
response to growth factorGO:00708481890.013
positive regulation of gene expressionGO:00106282440.013
proteolysisGO:00065081750.013
positive regulation of transportGO:00510502450.013
carbohydrate derivative metabolic processGO:19011353460.013
cellular response to acid chemicalGO:0071229750.013
developmental growthGO:00485891000.013
cellular glucan metabolic processGO:0006073230.013
axis specificationGO:000979840.013
regulation of apoptotic signaling pathwayGO:2001233130.013
cellular response to growth factor stimulusGO:00713631620.013
heart morphogenesisGO:000300730.013
regulation of response to stressGO:00801341260.013
single organism organelle organizationGO:19025891800.013
response to hexoseGO:00097461440.013
positive regulation of neurogenesisGO:00507691650.013
response to purine containing compoundGO:00140741260.012
learning or memoryGO:0007611900.012
response to ketoneGO:19016541820.012
regulation of proteasomal protein catabolic processGO:006113640.012
regulation of rna metabolic processGO:00512523910.012
fatty acid transportGO:0015908250.012
regulation of protein transportGO:0051223680.012
multi multicellular organism processGO:00447061380.012
positive regulation of apoptotic processGO:00430651540.012
development of primary sexual characteristicsGO:00451371070.012
protein tetramerizationGO:0051262380.012
insulin secretionGO:0030073690.012
negative regulation of cellular biosynthetic processGO:00313271610.012
response to glucoseGO:00097491360.012
cardiovascular system developmentGO:00723581340.012
regulation of transcription dna templatedGO:00063553740.012
positive regulation of mitochondrial membrane permeabilityGO:003579410.012
mitochondrion organizationGO:0007005350.012
cellular protein localizationGO:00346131220.012
regulation of system processGO:00440572080.012
positive regulation of cellular component organizationGO:00511302000.012
defense responseGO:00069521940.012
neurotransmitter biosynthetic processGO:004213620.012
regulation of neuron projection developmentGO:00109751610.012
regulation of transferase activityGO:00513381230.012
negative regulation of gene expressionGO:00106291990.012
cellular response to oxidative stressGO:0034599760.011
negative regulation of innate immune responseGO:004582440.011
macroautophagyGO:001623640.011
protein localization to organelleGO:0033365570.011
rna biosynthetic processGO:00327743800.011
sexual reproductionGO:00199531480.011
regenerationGO:00310991630.011
dephosphorylationGO:0016311980.011
positive regulation of neuron differentiationGO:00456661260.011
intracellular protein transportGO:0006886790.011
positive regulation of cell deathGO:00109421840.011
very long chain fatty acid metabolic processGO:000003830.011
glucose metabolic processGO:0006006520.011
inflammatory responseGO:00069541500.011
gamete generationGO:00072761240.011
cellular homeostasisGO:00197252520.011
sensory perceptionGO:00076001010.011
gastrulationGO:000736920.011
cellular response to cytokine stimulusGO:00713451270.011
cellular ion homeostasisGO:00068731840.011
positive regulation of rna metabolic processGO:00512542030.011
hormone metabolic processGO:0042445690.011
regulation of defense responseGO:0031347680.011
ion homeostasisGO:00508012120.011
response to cytokineGO:00340972150.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
locomotionGO:00400112370.011
response to starvationGO:0042594590.011
neuron deathGO:00709971270.010
peptidyl amino acid modificationGO:00181931260.010
regulation of neurotransmitter levelsGO:0001505420.010
female sex differentiationGO:0046660590.010
synaptic transmissionGO:00072682350.010
protein targetingGO:0006605610.010
positive regulation of catalytic activityGO:00430851840.010
cellular chemical homeostasisGO:00550822470.010
anterior posterior pattern specificationGO:000995210.010
bmp signaling pathwayGO:003050940.010
regulation of protein localizationGO:0032880810.010
neuron projection morphogenesisGO:00488121220.010
positive regulation of nucleic acid templated transcriptionGO:19035081970.010

Hadha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.030
musculoskeletal system diseaseDOID:1700.016
muscular diseaseDOID:008000000.014
muscle tissue diseaseDOID:6600.014
central nervous system diseaseDOID:33100.013
inherited metabolic disorderDOID:65500.012
disease of metabolismDOID:001466700.012
muscular dystrophyDOID:988400.012
myopathyDOID:42300.012