Rattus norvegicus

9 known processes

Obscn

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

Obscn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to oxygen levelsGO:00704822650.236
positive regulation of cell differentiationGO:00455972170.180
cellular chemical homeostasisGO:00550822470.158
positive regulation of developmental processGO:00510942830.157
response to blue lightGO:000963710.139
response to hypoxiaGO:00016662310.119
regulation of rna biosynthetic processGO:20011413810.112
cellular response to oxygen containing compoundGO:19017013860.109
cellular response to mechanical stimulusGO:0071260480.092
chemical homeostasisGO:00488782920.091
response to nutrient levelsGO:00316673700.090
muscle structure developmentGO:0061061870.079
cellular response to endogenous stimulusGO:00714953770.075
muscle cell differentiationGO:0042692520.075
homeostatic processGO:00425923310.073
protein complex biogenesisGO:00702712630.073
regulation of transcription dna templatedGO:00063553740.072
protein complex assemblyGO:00064612630.072
nucleic acid templated transcriptionGO:00976593790.072
response to extracellular stimulusGO:00099913800.072
positive regulation of multicellular organismal processGO:00512403870.070
cellular component morphogenesisGO:00329891550.070
cellular response to organonitrogen compoundGO:00714171970.069
muscle system processGO:00030121150.069
response to purine containing compoundGO:00140741260.068
cation transmembrane transportGO:00986552630.068
cellular response to abiotic stimulusGO:0071214850.067
positive regulation of nitrogen compound metabolic processGO:00511733340.065
cardiac muscle cell contractionGO:0086003100.064
protein complex subunit organizationGO:00718223020.062
regulation of neurogenesisGO:00507672470.062
cytoskeleton organizationGO:00070101110.061
inorganic cation transmembrane transportGO:00986622020.060
regulation of nucleic acid templated transcriptionGO:19035063800.060
cell projection morphogenesisGO:00488581230.060
cell projection organizationGO:00300303020.058
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.058
ion transmembrane transportGO:00342203650.058
neuron deathGO:00709971270.057
neuron differentiationGO:00301823680.057
cellular calcium ion homeostasisGO:00068741600.057
potassium ion transportGO:0006813970.055
positive regulation of nervous system developmentGO:00519621780.055
actin filament based movementGO:0030048160.054
cardiac muscle contractionGO:0060048270.054
regulation of striated muscle contractionGO:0006942210.052
nucleoside phosphate metabolic processGO:00067532830.052
regulation of cell differentiationGO:00455953200.051
response to cytokineGO:00340972150.051
regulation of rna metabolic processGO:00512523910.050
response to decreased oxygen levelsGO:00362932370.050
inorganic ion transmembrane transportGO:00986602290.050
actin mediated cell contractionGO:0070252120.049
regulation of neuron projection developmentGO:00109751610.048
positive regulation of ion transportGO:0043270940.048
carbohydrate derivative metabolic processGO:19011353460.048
positive regulation of neurogenesisGO:00507691650.048
response to electrical stimulus involved in regulation of muscle adaptationGO:001487840.048
brain developmentGO:00074202470.048
intracellular transportGO:00469071850.047
cellular homeostasisGO:00197252520.047
response to corticosteroidGO:00319602350.047
cellular component movementGO:00069282480.046
blood circulationGO:00080151830.046
l glutamate importGO:005193820.045
neuron projection morphogenesisGO:00488121220.045
central nervous system developmentGO:00074173110.045
anatomical structure morphogenesisGO:00096532980.045
head developmentGO:00603222470.043
positive regulation of biosynthetic processGO:00098913190.042
rna biosynthetic processGO:00327743800.042
regulation of system processGO:00440572080.042
tissue developmentGO:00098882520.041
circulatory system processGO:00030131830.040
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.040
cellular cation homeostasisGO:00300031800.040
cellular component biogenesisGO:00440853680.040
cellular component assemblyGO:00226073600.039
cardiac muscle cell developmentGO:0055013160.039
regulation of cellular localizationGO:00603412630.039
regulation of nervous system developmentGO:00519602640.038
single organism biosynthetic processGO:00447113420.038
organelle organizationGO:00069962660.037
regulation of dendrite developmentGO:0050773590.037
muscle tissue developmentGO:0060537580.036
potassium ion transmembrane transportGO:0071805710.036
cell morphogenesis involved in neuron differentiationGO:00486671060.036
sequestering of calcium ionGO:005120880.035
regulation of cellular component movementGO:00512701500.035
organic substance catabolic processGO:19015753160.035
cellular response to nitrogen compoundGO:19016992100.034
cellular catabolic processGO:00442482950.034
regulation of transcription from rna polymerase ii promoterGO:00063572340.033
cell part morphogenesisGO:00329901230.033
metal ion homeostasisGO:00550651860.033
cellular potassium ion transportGO:0071804720.033
response to glucocorticoidGO:00513842230.033
rna metabolic processGO:00160704060.033
circadian rhythmGO:0007623880.033
metal ion transportGO:00300012890.032
negative regulation of cell deathGO:00605482290.032
response to nutrientGO:00075842480.032
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.032
regulation of cardiac muscle contractionGO:0055117170.031
regulation of neuron deathGO:19012141150.031
heart contractionGO:0060047570.031
cellular response to hormone stimulusGO:00328702470.031
regulation of multicellular organismal developmentGO:20000263760.031
single organism behaviorGO:00447081300.031
negative regulation of nucleobase containing compound metabolic processGO:00459341530.031
calcium ion homeostasisGO:00550741620.031
membrane depolarization during action potentialGO:008601010.030
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.030
cell morphogenesis involved in differentiationGO:00009041190.030
cellular divalent inorganic cation homeostasisGO:00725031620.030
response to organophosphorusGO:00466831020.029
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.029
response to ketoneGO:19016541820.029
neuron apoptotic processGO:0051402880.029
nucleotide metabolic processGO:00091172790.029
regulation of cell projection organizationGO:00313441750.028
heart processGO:0003015570.028
organophosphate metabolic processGO:00196373700.028
regulation of cell developmentGO:00602842630.028
transcription dna templatedGO:00063513770.027
regulation of cellular catabolic processGO:00313291010.027
calcium ion transmembrane transportGO:0070588700.027
macromolecular complex assemblyGO:00650032730.027
cellular metal ion homeostasisGO:00068751720.027
regulation of ion transmembrane transporter activityGO:0032412480.026
cytoplasmic transportGO:00164821150.026
regulation of arp2 3 complex mediated actin nucleationGO:003431520.026
negative regulation of metabolic processGO:00098923310.025
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
regulation of neuron differentiationGO:00456642080.025
neuron developmentGO:00486662860.025
nucleoside phosphate catabolic processGO:19012921400.025
positive regulation of phosphorylationGO:00423271770.025
response to peptide hormoneGO:00434342780.025
single organism intracellular transportGO:19025821660.025
regulation of heart contractionGO:0008016480.024
cardiac ventricle developmentGO:000323110.024
sequestering of metal ionGO:005123890.024
carbohydrate derivative catabolic processGO:19011361470.024
actin filament based processGO:0030029860.024
regulation of cell proliferationGO:00421273590.023
regulation of membrane repolarizationGO:006030610.023
transmembrane transportGO:00550854120.023
transcription from rna polymerase ii promoterGO:00063662520.023
sarcoplasmic reticulum calcium ion transportGO:007029680.023
cellular ion homeostasisGO:00068731840.023
ribonucleoside metabolic processGO:00091191740.023
programmed cell deathGO:00125013920.023
regulation of actin filament based movementGO:1903115120.023
cellular response to stressGO:00335542690.023
regulation of catabolic processGO:00098941130.022
nucleoside catabolic processGO:00091641260.022
regulation of programmed cell deathGO:00430673410.022
divalent inorganic cation transportGO:00725111340.022
regulation of cellular component organizationGO:00511283680.022
response to estradiolGO:00323551640.021
cation homeostasisGO:00550801950.021
positive regulation of transcription dna templatedGO:00458931970.021
maintenance of locationGO:0051235170.021
heterocycle catabolic processGO:00467001670.021
response to ethanolGO:00454711620.021
regulation of establishment of planar polarityGO:009017520.021
striated muscle contractionGO:0006941440.021
response to molecule of bacterial originGO:00022371940.021
ventricular cardiac muscle cell action potentialGO:008600520.021
cellular response to external stimulusGO:00714961180.021
rhythmic processGO:00485111560.021
purine nucleoside triphosphate catabolic processGO:00091461220.021
oxoacid metabolic processGO:00434362900.020
positive regulation of molecular functionGO:00440932300.020
enzyme linked receptor protein signaling pathwayGO:00071671160.020
male sex differentiationGO:0046661640.020
positive regulation of transportGO:00510502450.020
striated muscle cell developmentGO:0055002260.020
cytosolic calcium ion homeostasisGO:00514801400.020
regulation of phosphorus metabolic processGO:00511743490.020
positive regulation of cellular component organizationGO:00511302000.020
ion homeostasisGO:00508012120.020
purine containing compound metabolic processGO:00725212530.020
divalent inorganic cation homeostasisGO:00725071650.019
female pregnancyGO:00075651220.019
monovalent inorganic cation transportGO:00156721720.019
actin cytoskeleton organizationGO:0030036730.019
purine nucleotide metabolic processGO:00061632290.019
purine containing compound catabolic processGO:00725231380.019
organonitrogen compound biosynthetic processGO:19015661670.019
negative regulation of cell differentiationGO:0045596990.019
regulation of ion transportGO:00432692450.019
regulation of molecular functionGO:00650093980.019
optic nerve developmentGO:002155430.019
regulation of stem cell differentiationGO:200073620.019
positive regulation of cellular biosynthetic processGO:00313282950.019
developmental process involved in reproductionGO:00030061590.019
regulation of intracellular signal transductionGO:19025312180.019
cellular protein complex assemblyGO:0043623440.019
eye developmentGO:0001654500.018
growthGO:00400071650.018
multicellular organismal signalingGO:0035637440.018
positive regulation of rna metabolic processGO:00512542030.018
sensory organ developmentGO:0007423740.018
catabolic processGO:00090563510.018
agingGO:00075682410.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
single organism organelle organizationGO:19025891800.018
response to biotic stimulusGO:00096072260.017
positive regulation of signal transductionGO:00099671750.017
regulation of neuron apoptotic processGO:0043523830.017
protein phosphorylationGO:00064683450.017
heart morphogenesisGO:000300730.017
positive regulation of neuron differentiationGO:00456661260.017
protein tetramerizationGO:0051262380.017
dendrite developmentGO:0016358720.017
positive regulation of neuron projection developmentGO:0010976990.017
response to carbohydrateGO:00097431830.017
protein heterooligomerizationGO:0051291890.017
skeletal muscle organ developmentGO:0060538330.017
regulation of cardiac muscle cell contractionGO:0086004110.016
ribonucleoside triphosphate metabolic processGO:00091991410.016
regulation of growthGO:00400081050.016
negative regulation of apoptotic processGO:00430661810.016
muscle organ developmentGO:0007517500.016
positive regulation of rna biosynthetic processGO:19026801970.016
regulation of muscle system processGO:0090257790.016
calcium ion transport into cytosolGO:0060402380.016
purine ribonucleotide metabolic processGO:00091502270.016
glycosyl compound metabolic processGO:19016571820.016
small gtpase mediated signal transductionGO:0007264360.016
cell morphogenesisGO:00009021420.015
cellular macromolecular complex assemblyGO:0034622580.015
cytosolic calcium ion transportGO:0060401390.015
bmp signaling pathwayGO:003050940.015
intracellular signal transductionGO:00355563140.015
cardiac chamber developmentGO:000320510.015
response to glucoseGO:00097491360.015
negative regulation of programmed cell deathGO:00430691830.015
positive regulation of cell developmentGO:00107201760.015
heart developmentGO:0007507720.015
second messenger mediated signalingGO:0019932510.015
positive regulation of response to stimulusGO:00485842850.015
cellular nitrogen compound catabolic processGO:00442701630.015
response to other organismGO:00517072200.014
regulation of cell morphogenesis involved in differentiationGO:0010769720.014
positive regulation of signalingGO:00230562700.014
male gonad developmentGO:0008584590.014
aromatic compound catabolic processGO:00194391680.014
lipid metabolic processGO:00066292830.014
protein polymerizationGO:0051258220.014
reproductive system developmentGO:00614581280.014
regulation of cellular component biogenesisGO:0044087860.014
nucleotide catabolic processGO:00091661390.014
oxidation reduction processGO:00551143040.014
cardiac conductionGO:006133720.014
sex differentiationGO:00075481130.014
regulation of metal ion transportGO:00109591180.014
nucleoside triphosphate catabolic processGO:00091431230.014
regulation of secretionGO:00510462240.014
organophosphate catabolic processGO:00464341480.014
locomotionGO:00400112370.013
negative regulation of mitotic cell cycle phase transitionGO:190199130.013
action potentialGO:0001508540.013
cellular response to lipidGO:00713962010.013
nucleobase containing small molecule metabolic processGO:00550863160.013
response to mechanical stimulusGO:00096121340.013
regulation of muscle contractionGO:0006937530.013
regulation of catalytic activityGO:00507903040.013
single organism catabolic processGO:00447122830.013
regulation of transmembrane transporter activityGO:0022898490.013
regulation of apoptotic processGO:00429813350.013
cellular response to insulin stimulusGO:0032869810.013
developmental growthGO:00485891000.013
development of primary male sexual characteristicsGO:0046546590.012
ribose phosphate metabolic processGO:00196932350.012
negative regulation of macromolecule metabolic processGO:00106052600.012
positive regulation of phagocytosis engulfmentGO:006010040.012
cellular amino acid metabolic processGO:00065201070.012
protein homotetramerizationGO:0051289250.012
regulation of cell morphogenesisGO:0022604770.012
positive regulation of cellular catabolic processGO:0031331710.012
motor neuron axon guidanceGO:000804510.012
regulation of cellular protein metabolic processGO:00322682670.012
cation transportGO:00068123820.012
regulation of protein complex assemblyGO:0043254330.012
ribonucleotide metabolic processGO:00092592310.012
gonad developmentGO:00084061040.012
protein localizationGO:00081041910.012
membrane repolarizationGO:008600910.012
positive regulation of potassium ion transmembrane transportGO:190138140.012
cellular response to organic cyclic compoundGO:00714072020.012
protein homooligomerizationGO:0051260910.012
negative regulation of calcium ion transport into cytosolGO:001052340.011
nucleoside metabolic processGO:00091161790.011
positive regulation of cellular component biogenesisGO:0044089550.011
negative regulation of arp2 3 complex mediated actin nucleationGO:003431610.011
response to toxic substanceGO:00096361330.011
neuron fate commitmentGO:004866340.011
nucleobase containing compound catabolic processGO:00346551520.011
protein oligomerizationGO:00512591910.011
negative regulation of gene expressionGO:00106291990.011
response to hexoseGO:00097461440.011
muscle cell developmentGO:0055001260.011
sarcomere organizationGO:004521460.011
purine nucleoside metabolic processGO:00422781690.011
regulation of blood circulationGO:19035221100.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
positive regulation of intracellular signal transductionGO:19025331380.011
negative regulation of cell cycle phase transitionGO:190198840.011
regulation of signal transductionGO:00099663180.011
erythrocyte homeostasisGO:003410120.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
ribonucleoside catabolic processGO:00424541260.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.010
muscle contractionGO:0006936880.010
cardiac muscle tissue morphogenesisGO:005500810.010
purine nucleotide catabolic processGO:00061951360.010
regulation of homeostatic processGO:00328441010.010
cellular ketone metabolic processGO:0042180510.010
cellular response to growth factor stimulusGO:00713631620.010
response to inorganic substanceGO:00100353770.010
positive regulation of cell communicationGO:00106472710.010
positive regulation of cell projection organizationGO:00313461110.010
positive regulation of ion transmembrane transportGO:0034767240.010
muscle organ morphogenesisGO:004864410.010
macromolecular complex subunit organizationGO:00439333390.010
ras protein signal transductionGO:0007265290.010
neurological system processGO:00508772190.010
regulation of intracellular transportGO:0032386650.010

Obscn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
long qt syndromeDOID:284300.216
cardiovascular system diseaseDOID:128700.164
disease of anatomical entityDOID:700.164
musculoskeletal system diseaseDOID:1700.121
myopathyDOID:42300.041
muscular diseaseDOID:008000000.041
heart diseaseDOID:11400.041
cardiomyopathyDOID:005070000.041
intrinsic cardiomyopathyDOID:006003600.041
dilated cardiomyopathyDOID:1293000.041
muscle tissue diseaseDOID:6600.041
disease of metabolismDOID:001466700.026
inherited metabolic disorderDOID:65500.026
nervous system diseaseDOID:86300.024