Rattus norvegicus

18 known processes

Nf2

neurofibromin 2 (merlin)

(Aliases: merlin)

Nf2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transcription dna templatedGO:00063553740.266
rna biosynthetic processGO:00327743800.189
apoptotic processGO:00069153810.135
Fly
transcription dna templatedGO:00063513770.132
regulation of nucleic acid templated transcriptionGO:19035063800.121
organelle organizationGO:00069962660.093
Human Rat Fly
regulation of rna biosynthetic processGO:20011413810.091
positive regulation of developmental processGO:00510942830.091
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353190.089
synaptic transmissionGO:00072682350.088
rna metabolic processGO:00160704060.080
response to growth factorGO:00708481890.079
Rat
ribonucleotide metabolic processGO:00092592310.076
transcription from rna polymerase ii promoterGO:00063662520.073
negative regulation of metabolic processGO:00098923310.073
Human Mouse
regulation of transcription from rna polymerase ii promoterGO:00063572340.068
positive regulation of nitrogen compound metabolic processGO:00511733340.068
regulation of cell developmentGO:00602842630.067
Fly
response to monosaccharideGO:00342841590.062
regulation of cell differentiationGO:00455953200.061
Mouse Fly
nucleic acid templated transcriptionGO:00976593790.061
neuron differentiationGO:00301823680.060
Fly
regulation of rna metabolic processGO:00512523910.060
purine ribonucleotide biosynthetic processGO:0009152810.059
cellular response to growth factor stimulusGO:00713631620.057
Rat
regulation of neuron projection developmentGO:00109751610.055
nucleotide metabolic processGO:00091172790.054
neuron developmentGO:00486662860.054
positive regulation of neurogenesisGO:00507691650.054
positive regulation of transportGO:00510502450.053
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189240.051
negative regulation of nervous system developmentGO:0051961790.050
Fly
nucleoside phosphate metabolic processGO:00067532830.049
nucleoside phosphate biosynthetic processGO:19012931020.049
regulation of neuron differentiationGO:00456642080.049
positive regulation of cellular biosynthetic processGO:00313282950.048
purine nucleotide metabolic processGO:00061632290.048
cyclic purine nucleotide metabolic processGO:0052652620.048
purine nucleotide biosynthetic processGO:0006164830.047
programmed cell deathGO:00125013920.046
Fly
purine containing compound metabolic processGO:00725212530.046
carbohydrate derivative metabolic processGO:19011353460.046
regulation of phosphorus metabolic processGO:00511743490.046
Human Mouse Fly
positive regulation of camp metabolic processGO:0030816310.045
regulation of apoptotic processGO:00429813350.045
Fly
regulation of purine nucleotide biosynthetic processGO:1900371460.044
regulation of cyclic nucleotide metabolic processGO:0030799510.042
protein complex subunit organizationGO:00718223020.042
Human Rat
regulation of nervous system developmentGO:00519602640.042
Fly
organophosphate metabolic processGO:00196373700.041
cell cell signalingGO:00072673350.041
Fly
ribonucleotide biosynthetic processGO:0009260850.041
positive regulation of cell differentiationGO:00455972170.040
Mouse
response to extracellular stimulusGO:00099913800.039
cellular response to endogenous stimulusGO:00714953770.036
Rat
negative regulation of transcription dna templatedGO:00458921160.036
nucleobase containing small molecule metabolic processGO:00550863160.036
enzyme linked receptor protein signaling pathwayGO:00071671160.036
Fly
response to cytokineGO:00340972150.036
negative regulation of macromolecule metabolic processGO:00106052600.036
Human Mouse
cellular component morphogenesisGO:00329891550.035
carboxylic acid metabolic processGO:00197522890.035
positive regulation of neuron projection developmentGO:0010976990.035
negative regulation of signalingGO:00230571570.035
Human Mouse
regulation of camp metabolic processGO:0030814430.034
positive regulation of neuron differentiationGO:00456661260.034
positive regulation of response to stimulusGO:00485842850.034
nucleotide biosynthetic processGO:0009165980.034
positive regulation of phosphate metabolic processGO:00459372620.034
Fly
cell growthGO:00160491040.034
negative regulation of nitrogen compound metabolic processGO:00511721610.034
Human
regulation of cell projection organizationGO:00313441750.034
positive regulation of rna biosynthetic processGO:19026801970.033
cellular component biogenesisGO:00440853680.033
Human Rat Fly
protein complex biogenesisGO:00702712630.033
Rat
single organism catabolic processGO:00447122830.032
positive regulation of multicellular organismal processGO:00512403870.032
reproductive processGO:00224143720.032
Fly
multi organism reproductive processGO:00447032620.032
Fly
organophosphate biosynthetic processGO:00904071430.032
regulation of phosphate metabolic processGO:00192203490.032
Human Mouse Fly
secretion by cellGO:00329402480.031
cardiovascular system developmentGO:00723581340.030
head developmentGO:00603222470.030
Mouse
positive regulation of macromolecule biosynthetic processGO:00105572470.030
negative regulation of gene expressionGO:00106291990.030
positive regulation of nervous system developmentGO:00519621780.030
single organism organelle organizationGO:19025891800.030
Human Rat
positive regulation of cell developmentGO:00107201760.029
purine containing compound biosynthetic processGO:0072522850.029
regulation of secretionGO:00510462240.029
cellular chemical homeostasisGO:00550822470.028
anatomical structure morphogenesisGO:00096532980.028
Mouse Fly
organonitrogen compound biosynthetic processGO:19015661670.028
response to hypoxiaGO:00016662310.028
protein localizationGO:00081041910.028
Mouse Rat Fly
regulation of neurogenesisGO:00507672470.028
Fly
catabolic processGO:00090563510.028
purine ribonucleotide metabolic processGO:00091502270.028
circulatory system developmentGO:00723591340.028
homeostatic processGO:00425923310.027
ribose phosphate metabolic processGO:00196932350.027
intracellular signal transductionGO:00355563140.027
Human Mouse Fly
positive regulation of gene expressionGO:00106282440.027
ribose phosphate biosynthetic processGO:0046390870.027
central nervous system developmentGO:00074173110.027
Mouse
response to transforming growth factor betaGO:0071559460.027
regulation of cyclic nucleotide biosynthetic processGO:0030802450.027
second messenger mediated signalingGO:0019932510.027
tissue developmentGO:00098882520.027
Mouse Rat
regulation of multicellular organismal developmentGO:20000263760.027
Fly
regulation of cellular amine metabolic processGO:003323880.027
regulation of anatomical structure morphogenesisGO:00226031410.026
Fly
regulation of cellular localizationGO:00603412630.026
Mouse
organic substance catabolic processGO:19015753160.026
cellular homeostasisGO:00197252520.026
negative regulation of rna metabolic processGO:00512531230.026
regulation of programmed cell deathGO:00430673410.026
Fly
cell projection organizationGO:00300303020.026
Rat
regulation of cellular ketone metabolic processGO:0010565270.025
positive regulation of cyclic nucleotide metabolic processGO:0030801370.025
development of primary sexual characteristicsGO:00451371070.025
cellular response to oxygen containing compoundGO:19017013860.025
negative regulation of programmed cell deathGO:00430691830.025
positive regulation of rna metabolic processGO:00512542030.024
neurological system processGO:00508772190.024
secretionGO:00469033070.024
regulation of homeostatic processGO:00328441010.024
negative regulation of cellular metabolic processGO:00313242810.024
Human Mouse
cyclic nucleotide metabolic processGO:0009187800.024
negative regulation of cell communicationGO:00106481580.023
Human Mouse
cellular calcium ion homeostasisGO:00068741600.023
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
Human
vasculature developmentGO:0001944700.023
single organism reproductive processGO:00447022970.023
Fly
motor neuron axon guidanceGO:000804510.023
carbohydrate derivative biosynthetic processGO:19011371240.023
cellular amino acid metabolic processGO:00065201070.023
regulation of nucleotide biosynthetic processGO:0030808470.023
negative regulation of nucleobase containing compound metabolic processGO:00459341530.023
Human
regulation of molecular functionGO:00650093980.023
Mouse
actin filament based processGO:0030029860.022
Human Rat
cell projection morphogenesisGO:00488581230.022
cyclic nucleotide biosynthetic processGO:0009190630.022
cellular divalent inorganic cation homeostasisGO:00725031620.022
negative regulation of phosphorus metabolic processGO:0010563800.022
Human Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858210.022
bmp signaling pathwayGO:003050940.022
positive regulation of cytosolic calcium ion concentrationGO:00072041220.022
nucleoside metabolic processGO:00091161790.022
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.022
regulation of cell proliferationGO:00421273590.022
Human Mouse Fly
organophosphate catabolic processGO:00464341480.022
cellular component assemblyGO:00226073600.022
Human Rat Fly
regulation of phosphorylationGO:00423252480.021
Human Mouse Fly
negative regulation of apoptotic processGO:00430661810.021
response to hexoseGO:00097461440.021
brain developmentGO:00074202470.021
Mouse
g protein coupled receptor signaling pathwayGO:00071862420.021
positive regulation of cell deathGO:00109421840.021
macromolecular complex assemblyGO:00650032730.021
Rat
cellular catabolic processGO:00442482950.021
positive regulation of biosynthetic processGO:00098913190.021
regulation of nucleotide metabolic processGO:00061401170.020
regulation of cellular component organizationGO:00511283680.020
divalent inorganic cation homeostasisGO:00725071650.020
positive regulation of secretionGO:00510471400.020
ion homeostasisGO:00508012120.020
cellular ketone metabolic processGO:0042180510.020
sulfur amino acid metabolic processGO:000009690.019
response to decreased oxygen levelsGO:00362932370.019
multicellular organismal signalingGO:0035637440.019
lipid metabolic processGO:00066292830.019
cellular response to stressGO:00335542690.019
negative regulation of rna biosynthetic processGO:19026791180.019
cellular amine metabolic processGO:0044106380.019
macromolecule localizationGO:00330362520.019
Mouse Rat Fly
cellular component movementGO:00069282480.019
positive regulation of transcription dna templatedGO:00458931970.019
regulation of synaptic plasticityGO:0048167700.019
sexual reproductionGO:00199531480.018
Fly
neuron projection developmentGO:00311752730.018
regulation of purine nucleotide metabolic processGO:19005421150.018
cell morphogenesis involved in neuron differentiationGO:00486671060.018
positive regulation of phosphorus metabolic processGO:00105622620.018
Fly
negative regulation of cellular component organizationGO:0051129830.018
Rat
circulatory system processGO:00030131830.018
regulation of secretion by cellGO:19035302080.018
organic acid metabolic processGO:00060822920.018
positive regulation of signalingGO:00230562700.018
negative regulation of multicellular organismal processGO:00512412030.018
Fly
negative regulation of cell deathGO:00605482290.018
chromosome segregationGO:000705920.018
Fly
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
cell type specific apoptotic processGO:00972851340.017
multicellular organism reproductionGO:00325042330.017
Fly
positive regulation of purine nucleotide biosynthetic processGO:1900373360.017
nucleoside phosphate catabolic processGO:19012921400.017
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.017
cellular response to cytokine stimulusGO:00713451270.017
cytoskeleton organizationGO:00070101110.017
Human Rat
behaviorGO:00076102050.017
Fly
response to nutrient levelsGO:00316673700.017
purine nucleoside catabolic processGO:00061521240.017
positive regulation of camp biosynthetic processGO:0030819280.017
regulation of ion transportGO:00432692450.017
response to carbohydrateGO:00097431830.017
amine metabolic processGO:0009308380.017
cellular metal ion homeostasisGO:00068751720.017
cardiac ventricle developmentGO:000323110.017
respiratory gaseous exchangeGO:000758540.017
cardiac muscle tissue morphogenesisGO:005500810.017
positive regulation of nucleotide biosynthetic processGO:0030810360.016
response to glucoseGO:00097491360.016
regulation of neuron deathGO:19012141150.016
glycosyl compound metabolic processGO:19016571820.016
regulation of blood pressureGO:0008217830.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
camp metabolic processGO:0046058630.016
protein phosphorylationGO:00064683450.016
Human Mouse Fly
regulation of cellular amino acid metabolic processGO:000652120.016
defense responseGO:00069521940.016
tube developmentGO:0035295890.016
Mouse
single organism biosynthetic processGO:00447113420.016
regulation of cell morphogenesis involved in differentiationGO:0010769720.016
response to oxygen levelsGO:00704822650.016
metal ion transportGO:00300012890.016
anatomical structure formation involved in morphogenesisGO:0048646830.016
Mouse Fly
skeletal system developmentGO:0001501410.016
organic cyclic compound catabolic processGO:19013611750.016
cytosolic calcium ion homeostasisGO:00514801400.016
divalent inorganic cation transportGO:00725111340.016
cell morphogenesisGO:00009021420.016
establishment of protein localizationGO:00451841410.015
cellular response to organonitrogen compoundGO:00714171970.015
negative regulation of cellular biosynthetic processGO:00313271610.015
Human
protein transportGO:00150311320.015
positive regulation of cellular amine metabolic processGO:003324030.015
regulation of signal transductionGO:00099663180.015
Human Mouse Fly
negative regulation of macromolecule biosynthetic processGO:00105581480.015
Human
multicellular organismal reproductive processGO:00486092330.015
Fly
regulation of anatomical structure sizeGO:00900661350.015
Rat
purine ribonucleoside metabolic processGO:00461281680.015
signal releaseGO:00230611450.015
female pregnancyGO:00075651220.014
cellular lipid metabolic processGO:00442552080.014
macromolecular complex subunit organizationGO:00439333390.014
Human Rat
positive regulation of nucleotide metabolic processGO:0045981910.014
membrane repolarizationGO:008600910.014
negative regulation of biosynthetic processGO:00098901680.014
Human
positive regulation of cell projection organizationGO:00313461110.014
purine nucleoside metabolic processGO:00422781690.014
cellular protein localizationGO:00346131220.014
Mouse Fly
oxoacid metabolic processGO:00434362900.014
male sex differentiationGO:0046661640.014
regulation of cellular protein metabolic processGO:00322682670.014
Human Mouse Fly
protein complex assemblyGO:00064612630.014
Rat
positive regulation of ion transportGO:0043270940.014
cognitionGO:0050890920.014
positive regulation of secretion by cellGO:19035321280.014
cellular response to nitrogen compoundGO:19016992100.014
myeloid leukocyte activationGO:0002274360.014
positive regulation of cellular component organizationGO:00511302000.014
Human
ras protein signal transductionGO:0007265290.014
muscle tissue morphogenesisGO:006041510.014
organonitrogen compound catabolic processGO:19015651790.014
negative regulation of response to stimulusGO:00485851550.014
Human Mouse
metal ion homeostasisGO:00550651860.014
negative regulation of nucleic acid templated transcriptionGO:19035071170.014
sex differentiationGO:00075481130.014
muscle structure developmentGO:0061061870.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
cytokine mediated signaling pathwayGO:0019221430.014
heart morphogenesisGO:000300730.014
heterocycle catabolic processGO:00467001670.013
negative regulation of cell developmentGO:0010721820.013
Fly
ribonucleoside metabolic processGO:00091191740.013
cation homeostasisGO:00550801950.013
exocytosisGO:0006887600.013
regulation of dendrite developmentGO:0050773590.013
purine ribonucleoside monophosphate catabolic processGO:0009169550.013
appendage morphogenesisGO:003510740.013
Fly
regulation of lyase activityGO:0051339220.013
single organism intracellular transportGO:19025821660.013
Fly
purine nucleoside monophosphate metabolic processGO:0009126840.013
positive regulation of apoptotic processGO:00430651540.013
regulation of protein modification processGO:00313991940.013
Human Mouse Fly
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.013
nucleoside triphosphate metabolic processGO:00091411440.013
small gtpase mediated signal transductionGO:0007264360.013
regulation of synaptic transmissionGO:00508041410.013
sensory perceptionGO:00076001010.013
response to bacteriumGO:00096172000.013
response to interleukin 1GO:0070555550.013
reproductionGO:00000032450.013
Fly
inorganic cation transmembrane transportGO:00986622020.013
chemical homeostasisGO:00488782920.012
reproductive system developmentGO:00614581280.012
calcium ion homeostasisGO:00550741620.012
ribonucleotide catabolic processGO:00092611360.012
alpha amino acid metabolic processGO:1901605710.012
mechanoreceptor differentiationGO:004249020.012
ribonucleoside monophosphate metabolic processGO:0009161880.012
adult locomotory behaviorGO:000834440.012
neuron projection morphogenesisGO:00488121220.012
ion transmembrane transportGO:00342203650.012
regulation of hydrolase activityGO:00513361430.012
response to organophosphorusGO:00466831020.012
negative regulation of neuron differentiationGO:0045665620.012
cytokine productionGO:0001816610.012
response to cocaineGO:0042220390.012
response to nutrientGO:00075842480.012
activation of cysteine type endopeptidase activityGO:009720240.012
regulation of catalytic activityGO:00507903040.012
Mouse
intracellular transportGO:00469071850.012
Fly
response to inorganic substanceGO:00100353770.012
negative regulation of developmental processGO:00510931250.012
Fly
negative regulation of transportGO:00510511360.012
oxidation reduction processGO:00551143040.012
cell part morphogenesisGO:00329901230.012
regulation of calcium ion transportGO:0051924770.012
axon developmentGO:0061564960.011
regulation of cell morphogenesisGO:0022604770.011
peptide transportGO:0015833970.011
organ formationGO:004864530.011
regulation of catecholamine secretionGO:0050433320.011
localization of cellGO:00516742020.011
hormone secretionGO:00468791150.011
regulation of camp biosynthetic processGO:0030817380.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.011
regulation of blood circulationGO:19035221100.011
rhythmic processGO:00485111560.011
regulation of cyclase activityGO:0031279210.011
multicellular organism growthGO:003526410.011
striated muscle contractionGO:0006941440.011
negative regulation of neurogenesisGO:0050768780.011
Fly
negative regulation of molecular functionGO:00440921330.011
Mouse
purine containing compound catabolic processGO:00725231380.011
agingGO:00075682410.011
positive regulation of molecular functionGO:00440932300.011
gamete generationGO:00072761240.011
Fly
response to ethanolGO:00454711620.011
positive regulation of cell proliferationGO:00082842490.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.011
ribonucleoside catabolic processGO:00424541260.010
proteolysisGO:00065081750.010
vascular process in circulatory systemGO:0003018960.010
angiogenesisGO:0001525530.010
nucleobase containing compound catabolic processGO:00346551520.010
cell morphogenesis involved in differentiationGO:00009041190.010
positive regulation of cell communicationGO:00106472710.010
regulation of membrane potentialGO:00423911100.010
cation transportGO:00068123820.010
amide transportGO:00428861050.010
purine nucleotide catabolic processGO:00061951360.010
negative regulation of secretionGO:0051048820.010
cell fate determinationGO:000170920.010
protein oligomerizationGO:00512591910.010
regulation of sodium ion transportGO:0002028210.010
anterior posterior pattern specificationGO:000995210.010
Fly

Nf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.025
disease of anatomical entityDOID:700.025
muscular diseaseDOID:008000000.019
musculoskeletal system diseaseDOID:1700.019
muscle tissue diseaseDOID:6600.019
myopathyDOID:42300.017
nervous system diseaseDOID:86300.016
central nervous system diseaseDOID:33100.014