Rattus norvegicus

121 known processes

Nf1

neurofibromin 1

Nf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of phosphate metabolic processGO:00192203490.268
macromolecular complex subunit organizationGO:00439333390.239
Mouse
rna metabolic processGO:00160704060.193
positive regulation of cell communicationGO:00106472710.154
Mouse
regulation of intracellular signal transductionGO:19025312180.143
regulation of cellular protein metabolic processGO:00322682670.142
Mouse
cation transportGO:00068123820.138
intracellular signal transductionGO:00355563140.126
Human Zebrafish Mouse
reproductive processGO:00224143720.119
cellular protein localizationGO:00346131220.109
Mouse
regulation of phosphorus metabolic processGO:00511743490.107
positive regulation of molecular functionGO:00440932300.094
Human Mouse
negative regulation of metabolic processGO:00098923310.088
Human Zebrafish Mouse
programmed cell deathGO:00125013920.087
Mouse
negative regulation of signalingGO:00230571570.086
Human Zebrafish Mouse
single organism biosynthetic processGO:00447113420.082
Mouse
sarcoplasmic reticulum calcium ion transportGO:007029680.080
homeostatic processGO:00425923310.078
Mouse
negative regulation of nitrogen compound metabolic processGO:00511721610.074
negative regulation of macromolecule metabolic processGO:00106052600.073
Mouse
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.068
macromolecular complex assemblyGO:00650032730.065
cell type specific apoptotic processGO:00972851340.064
Mouse
single organism intracellular transportGO:19025821660.064
Mouse
calcium ion importGO:0070509220.063
protein phosphorylationGO:00064683450.059
Mouse
rna biosynthetic processGO:00327743800.059
positive regulation of signalingGO:00230562700.058
Mouse
cellular divalent inorganic cation homeostasisGO:00725031620.058
regulation of phosphorylationGO:00423252480.058
Human Zebrafish Mouse
regulation of nucleic acid templated transcriptionGO:19035063800.057
purine ribonucleotide metabolic processGO:00091502270.056
purine ribonucleotide biosynthetic processGO:0009152810.054
Mouse
locomotory exploration behaviorGO:003564110.054
protein localizationGO:00081041910.054
Mouse
regulation of muscle contractionGO:0006937530.054
cognitionGO:0050890920.054
Human Mouse
organic substance catabolic processGO:19015753160.053
positive regulation of phosphorus metabolic processGO:00105622620.052
Human Mouse
circadian rhythmGO:0007623880.052
positive regulation of biosynthetic processGO:00098913190.052
Mouse
metal ion homeostasisGO:00550651860.050
cellular component assemblyGO:00226073600.050
protein complex subunit organizationGO:00718223020.049
Mouse
cation homeostasisGO:00550801950.048
regulation of signal transductionGO:00099663180.048
central nervous system developmentGO:00074173110.047
Mouse
negative regulation of cellular metabolic processGO:00313242810.046
Human Zebrafish Mouse
maintenance of locationGO:0051235170.045
protein complex assemblyGO:00064612630.045
cellular response to external stimulusGO:00714961180.045
multi organism reproductive processGO:00447032620.042
regulation of peptide secretionGO:0002791820.042
rhythmic processGO:00485111560.041
neurological system processGO:00508772190.041
Human Mouse
transcription dna templatedGO:00063513770.041
purine containing compound metabolic processGO:00725212530.041
regulation of transmembrane transportGO:00347621220.040
purine nucleotide metabolic processGO:00061632290.040
cellular metal ion homeostasisGO:00068751720.040
regulation of purine nucleotide metabolic processGO:19005421150.040
blood circulationGO:00080151830.039
regulation of ion transmembrane transportGO:00347651210.038
inorganic cation transmembrane transportGO:00986622020.038
small gtpase mediated signal transductionGO:0007264360.037
Mouse
single organism reproductive processGO:00447022970.037
regulation of catalytic activityGO:00507903040.035
protein oligomerizationGO:00512591910.035
regulation of molecular functionGO:00650093980.035
ras protein signal transductionGO:0007265290.035
Mouse
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.034
organophosphate metabolic processGO:00196373700.034
regulation of programmed cell deathGO:00430673410.034
Mouse
calcium ion transportGO:00068161310.034
sequestering of metal ionGO:005123890.034
ossificationGO:0001503700.033
Mouse
positive regulation of cellular amino acid metabolic processGO:004576410.033
nucleoside phosphate biosynthetic processGO:19012931020.033
Mouse
secretionGO:00469033070.033
Mouse
insulin like growth factor receptor signaling pathwayGO:004800930.031
positive regulation of mapk cascadeGO:0043410920.031
negative regulation of cell deathGO:00605482290.031
positive regulation of cell proliferationGO:00082842490.031
Mouse
sex differentiationGO:00075481130.030
regulation of small gtpase mediated signal transductionGO:0051056480.030
positive regulation of intracellular signal transductionGO:19025331380.030
cellular catabolic processGO:00442482950.029
nucleoside phosphate metabolic processGO:00067532830.029
oxidation reduction processGO:00551143040.029
positive regulation of nitrogen compound metabolic processGO:00511733340.029
Human Mouse
cellular ketone metabolic processGO:0042180510.029
ribose phosphate metabolic processGO:00196932350.029
defecationGO:003042110.029
negative regulation of multicellular organismal processGO:00512412030.028
Mouse
single organism cellular localizationGO:19025801020.028
Mouse
single organism behaviorGO:00447081300.028
Mouse
regulation of secretionGO:00510462240.027
Mouse
protein transportGO:00150311320.027
Mouse
regulation of cardiac muscle contractionGO:0055117170.027
divalent inorganic cation transportGO:00725111340.027
regulation of transcription dna templatedGO:00063553740.026
positive regulation of behaviorGO:0048520380.026
cellular response to lipidGO:00713962010.026
circulatory system developmentGO:00723591340.026
Human Zebrafish Mouse
apoptotic processGO:00069153810.026
Mouse
cellular component biogenesisGO:00440853680.025
cellular amine metabolic processGO:0044106380.025
epinephrine secretionGO:004824260.025
negative regulation of signal transductionGO:0009968830.025
Human Zebrafish Mouse
cellular response to endogenous stimulusGO:00714953770.025
response to hypoxiaGO:00016662310.025
Mouse
carbohydrate derivative biosynthetic processGO:19011371240.025
Mouse
ribonucleotide metabolic processGO:00092592310.025
ion transmembrane transportGO:00342203650.024
nucleobase containing small molecule metabolic processGO:00550863160.024
cytosolic calcium ion homeostasisGO:00514801400.024
striated muscle tissue developmentGO:0014706580.024
Mouse
regulation of peptide transportGO:0090087870.024
regulation of tube sizeGO:0035150890.024
cellular ion homeostasisGO:00068731840.024
circulatory system processGO:00030131830.023
neuron differentiationGO:00301823680.023
positive regulation of protein metabolic processGO:00512471780.023
negative regulation of innate immune responseGO:004582440.022
aromatic compound catabolic processGO:00194391680.022
cellular calcium ion homeostasisGO:00068741600.022
response to mechanical stimulusGO:00096121340.022
multi multicellular organism processGO:00447061380.022
carbohydrate derivative metabolic processGO:19011353460.022
divalent metal ion transportGO:00708381320.022
regulation of anatomical structure sizeGO:00900661350.022
ion homeostasisGO:00508012120.022
brain developmentGO:00074202470.022
Mouse
cytosolic calcium ion transportGO:0060401390.021
calcium ion homeostasisGO:00550741620.021
motor neuron axon guidanceGO:000804510.021
protein complex biogenesisGO:00702712630.021
negative regulation of ion transportGO:0043271510.021
protein heterooligomerizationGO:0051291890.021
regulation of protein metabolic processGO:00512462890.021
Mouse
positive regulation of phosphorylationGO:00423271770.020
metal ion transportGO:00300012890.020
divalent inorganic cation homeostasisGO:00725071650.020
urinary bladder smooth muscle contractionGO:001483240.020
catabolic processGO:00090563510.020
peptidyl amino acid modificationGO:00181931260.020
ribonucleotide biosynthetic processGO:0009260850.020
Mouse
development of primary sexual characteristicsGO:00451371070.020
nucleoside phosphate catabolic processGO:19012921400.020
regulation of protein phosphorylationGO:00019321830.020
Mouse
regulation of rna biosynthetic processGO:20011413810.020
peptide secretionGO:0002790860.020
intracellular transportGO:00469071850.019
Mouse
cellular cation homeostasisGO:00300031800.019
regulation of hydrolase activityGO:00513361430.019
regulation of organ formationGO:000315620.019
negative regulation of gene expressionGO:00106291990.019
establishment of protein localizationGO:00451841410.019
Mouse
response to estrogenGO:00436272320.019
cardiovascular system developmentGO:00723581340.019
Human Zebrafish Mouse
agingGO:00075682410.019
response to metal ionGO:00100382530.019
muscle cell proliferationGO:0033002840.019
nitrogen compound transportGO:00717052290.019
regulation of intracellular transportGO:0032386650.019
Mouse
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.019
cytoplasmic transportGO:00164821150.019
Mouse
calcium ion transport into cytosolGO:0060402380.019
regulation of blood circulationGO:19035221100.019
regulation of blood vessel sizeGO:0050880890.019
asymmetric stem cell divisionGO:009872220.019
gonad developmentGO:00084061040.018
positive regulation of phosphate metabolic processGO:00459372620.018
Human Mouse
negative regulation of transportGO:00510511360.018
Mouse
behaviorGO:00076102050.018
Mouse
glycogen metabolic processGO:0005977230.018
second messenger mediated signalingGO:0019932510.018
male germ line stem cell asymmetric divisionGO:004813310.018
response to reactive oxygen speciesGO:00003021200.018
regulation of synaptic transmissionGO:00508041410.017
Mouse
vasoconstrictionGO:0042310540.017
response to inorganic substanceGO:00100353770.017
regulation of cellular localizationGO:00603412630.017
Mouse
transmembrane transportGO:00550854120.017
dna metabolic processGO:0006259960.017
regulation of exocytosisGO:0017157370.017
head developmentGO:00603222470.017
Mouse
cellular response to magnesium ionGO:007128640.017
glycogen biosynthetic processGO:0005978150.017
positive regulation of locomotionGO:00400171020.017
negative regulation of smooth muscle cell proliferationGO:0048662210.016
purine ribonucleotide catabolic processGO:00091541360.016
germline stem cell asymmetric divisionGO:009872810.016
positive regulation of serotonin secretionGO:001406410.016
regulation of feeding behaviorGO:0060259140.016
response to glucocorticoidGO:00513842230.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
sleepGO:0030431300.016
neuromuscular synaptic transmissionGO:000727420.016
vascular process in circulatory systemGO:0003018960.016
multicellular organism reproductionGO:00325042330.016
nucleotide metabolic processGO:00091172790.016
cellular component movementGO:00069282480.016
Human Mouse
cardiac muscle cell contractionGO:0086003100.016
dopamine metabolic processGO:0042417120.016
regulation of rna metabolic processGO:00512523910.016
regulation of nervous system developmentGO:00519602640.016
macromolecule localizationGO:00330362520.015
Mouse
cell motilityGO:00488702020.015
Human Mouse
negative regulation of neuron deathGO:1901215690.015
organic cyclic compound catabolic processGO:19013611750.015
transcription from rna polymerase ii promoterGO:00063662520.015
regulation of nucleotide metabolic processGO:00061401170.015
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.015
amine metabolic processGO:0009308380.015
positive regulation of catalytic activityGO:00430851840.015
Human Mouse
negative regulation of protein metabolic processGO:00512481140.015
Mouse
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
salivary gland developmentGO:000743130.015
regulation of cell proliferationGO:00421273590.015
Human Zebrafish Mouse
feeding behaviorGO:0007631530.015
regulation of cellular amine metabolic processGO:003323880.015
sequestering of calcium ionGO:005120880.015
defense response to gram negative bacteriumGO:005082930.015
reproductionGO:00000032450.015
response to decreased oxygen levelsGO:00362932370.015
Mouse
purine ribonucleoside metabolic processGO:00461281680.014
regulation of actin filament based processGO:0032970420.014
cellular response to organic cyclic compoundGO:00714072020.014
endoplasmic reticulum to cytosol transportGO:190351340.014
positive regulation of nucleotide metabolic processGO:0045981910.014
Human Mouse
response to carbohydrateGO:00097431830.014
positive regulation of cellular biosynthetic processGO:00313282950.014
Mouse
regulation of protein modification processGO:00313991940.014
Mouse
regulation of ras protein signal transductionGO:0046578450.014
muscle structure developmentGO:0061061870.014
Mouse
action potentialGO:0001508540.014
Mouse
nucleic acid templated transcriptionGO:00976593790.014
response to anoxiaGO:003405940.014
positive regulation of purine nucleotide metabolic processGO:1900544910.014
Human Mouse
negative regulation of cell proliferationGO:00082851190.014
Human Mouse
epithelium developmentGO:0060429960.014
Mouse
response to oxygen levelsGO:00704822650.014
Mouse
biological adhesionGO:00226101100.014
Mouse
cellular response to hormone stimulusGO:00328702470.014
negative regulation of biosynthetic processGO:00098901680.013
negative regulation of response to stimulusGO:00485851550.013
Human Zebrafish Mouse
regulation of transferase activityGO:00513381230.013
Mouse
chemical homeostasisGO:00488782920.013
circadian sleep wake cycleGO:0042745230.013
cyclic purine nucleotide metabolic processGO:0052652620.013
Mouse
single organism catabolic processGO:00447122830.013
sensory perception of painGO:0019233730.013
lipid metabolic processGO:00066292830.013
cellular macromolecule localizationGO:00707271220.013
Mouse
negative regulation of secretion by cellGO:1903531720.013
Mouse
protein autophosphorylationGO:0046777660.013
nucleobase containing compound catabolic processGO:00346551520.013
heart contractionGO:0060047570.013
glycerolipid metabolic processGO:0046486670.013
positive regulation of blood circulationGO:1903524650.013
adult locomotory behaviorGO:000834440.013
memoryGO:0007613540.013
negative regulation of ion transmembrane transportGO:0034766160.013
reactive oxygen species biosynthetic processGO:190340980.013
positive regulation of cyclase activityGO:0031281150.013
Mouse
negative regulation of apoptotic processGO:00430661810.013
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.013
regulation of neuron differentiationGO:00456642080.013
regulation of apoptotic processGO:00429813350.013
Mouse
negative regulation of transporter activityGO:0032410130.012
regulation of cellular amino acid metabolic processGO:000652120.012
t cell tolerance inductionGO:000251730.012
positive regulation of cell activationGO:0050867340.012
regulation of cyclic nucleotide metabolic processGO:0030799510.012
Mouse
rho protein signal transductionGO:0007266110.012
organophosphate biosynthetic processGO:00904071430.012
Mouse
cell migrationGO:00164771970.012
Human Mouse
glucan metabolic processGO:0044042230.012
regulation of system processGO:00440572080.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.012
regulation of vesicle mediated transportGO:0060627810.012
glucan biosynthetic processGO:0009250150.012
regulation of sodium ion transmembrane transporter activityGO:200064940.012
heart morphogenesisGO:000300730.012
regulation of homeostatic processGO:00328441010.012
Mouse
regulation of cellular ketone metabolic processGO:0010565270.012
actin filament based processGO:0030029860.012
Mouse
regulation of cyclic nucleotide biosynthetic processGO:0030802450.012
Mouse
nucleoside metabolic processGO:00091161790.012
multicellular organism growthGO:003526410.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
regulation of neuron deathGO:19012141150.012
Mouse
monoamine transportGO:0015844430.012
cellular polysaccharide metabolic processGO:0044264230.012
response to peptideGO:19016522920.012
organophosphate catabolic processGO:00464341480.012
smooth muscle cell proliferationGO:0048659770.012
cyclic nucleotide biosynthetic processGO:0009190630.012
Mouse
positive regulation of cell developmentGO:00107201760.011
regulation of smooth muscle cell proliferationGO:0048660750.011
cellular nitrogen compound catabolic processGO:00442701630.011
circadian sleep wake cycle processGO:0022410210.011
regulation of cell differentiationGO:00455953200.011
neuron projection developmentGO:00311752730.011
organ formationGO:004864530.011
calcium ion exportGO:190166060.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
response to external biotic stimulusGO:00432072210.011
negative regulation of calcium ion importGO:009028120.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
peptidyl tyrosine phosphorylationGO:0018108720.011
cellular chemical homeostasisGO:00550822470.011
exploration behaviorGO:003564010.011
cellular response to oxygen containing compoundGO:19017013860.011
axis specificationGO:000979840.011
positive regulation of cell differentiationGO:00455972170.011
response to interleukin 15GO:007067240.011
nucleoside triphosphate metabolic processGO:00091411440.011
regulation of cell migrationGO:00303341280.011
Human Mouse
macromolecule catabolic processGO:0009057580.011
response to ammonium ionGO:0060359710.011
regulation of cell developmentGO:00602842630.011
cell morphogenesisGO:00009021420.011
ribonucleoside metabolic processGO:00091191740.010
response to ethanolGO:00454711620.010
inorganic ion transmembrane transportGO:00986602290.010
cellular homeostasisGO:00197252520.010
adult behaviorGO:0030534160.010
regulation of catabolic processGO:00098941130.010
potassium ion transportGO:0006813970.010
negative regulation of cellular biosynthetic processGO:00313271610.010
cellular response to steroid hormone stimulusGO:0071383930.010
regulation of canonical wnt signaling pathwayGO:006082840.010
regulation of calcium ion transportGO:0051924770.010
regulation of norepinephrine secretionGO:0014061150.010
coronary vasculature morphogenesisGO:006097730.010
peptide hormone secretionGO:0030072840.010
regulation of anatomical structure morphogenesisGO:00226031410.010
Human Mouse
positive regulation of protein serine threonine kinase activityGO:0071902520.010

Nf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of mental healthDOID:15000.034
substance related disorderDOID:30300.034
substance dependenceDOID:997300.034
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
central nervous system diseaseDOID:33100.021