Rattus norvegicus

18 known processes

Ptprs

protein tyrosine phosphatase, receptor type, S

(Aliases: Rptpd,Larptp2,Ptpsigma.,Ptprd,Ptpsigma,MGC124537)

Ptprs biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of multicellular organismal developmentGO:20000263760.486
regulation of synaptic growth at neuromuscular junctionGO:000858210.380
synaptic growth at neuromuscular junctionGO:005112410.367
neuron differentiationGO:00301823680.366
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.344
anatomical structure morphogenesisGO:00096532980.342
synapse assemblyGO:0007416290.326
head developmentGO:00603222470.317
central nervous system developmentGO:00074173110.288
cellular component morphogenesisGO:00329891550.265
regulation of cellular component organizationGO:00511283680.264
regulation of nervous system developmentGO:00519602640.249
neuron apoptotic processGO:0051402880.248
synapse organizationGO:0050808460.232
axon developmentGO:0061564960.231
cell projection organizationGO:00300303020.229
regulation of neuron differentiationGO:00456642080.222
single organism carbohydrate metabolic processGO:00447231180.222
positive regulation of macromolecule biosynthetic processGO:00105572470.220
cellular component biogenesisGO:00440853680.216
protein complex subunit organizationGO:00718223020.214
regulation of neuron projection developmentGO:00109751610.212
cell part morphogenesisGO:00329901230.203
cell morphogenesis involved in neuron differentiationGO:00486671060.200
neuron developmentGO:00486662860.189
positive regulation of cell communicationGO:00106472710.189
positive regulation of gene expressionGO:00106282440.188
cell morphogenesis involved in differentiationGO:00009041190.186
catabolic processGO:00090563510.185
vesicle mediated transportGO:00161921810.185
regulation of cell differentiationGO:00455953200.184
axonogenesisGO:0007409710.183
macromolecule localizationGO:00330362520.176
positive regulation of multicellular organismal processGO:00512403870.176
regulation of signal transductionGO:00099663180.175
regulation of cell developmentGO:00602842630.174
regulation of anatomical structure morphogenesisGO:00226031410.169
neuron projection morphogenesisGO:00488121220.168
positive regulation of nucleobase containing compound metabolic processGO:00459353190.164
locomotionGO:00400112370.162
neuron projection developmentGO:00311752730.162
cellular component assemblyGO:00226073600.160
programmed cell deathGO:00125013920.159
regulation of phosphate metabolic processGO:00192203490.158
regulation of rna biosynthetic processGO:20011413810.153
establishment of protein localizationGO:00451841410.149
positive regulation of nervous system developmentGO:00519621780.149
cellular component movementGO:00069282480.149
positive regulation of biosynthetic processGO:00098913190.148
cell projection morphogenesisGO:00488581230.148
apoptotic processGO:00069153810.146
organophosphate metabolic processGO:00196373700.143
cell motilityGO:00488702020.142
tissue developmentGO:00098882520.140
carbohydrate metabolic processGO:00059751300.139
organic acid metabolic processGO:00060822920.139
brain developmentGO:00074202470.136
intracellular signal transductionGO:00355563140.136
neuron deathGO:00709971270.136
biological adhesionGO:00226101100.133
regulation of neurogenesisGO:00507672470.132
single organism organelle organizationGO:19025891800.131
growthGO:00400071650.131
cellular lipid metabolic processGO:00442552080.129
single organism catabolic processGO:00447122830.129
enzyme linked receptor protein signaling pathwayGO:00071671160.128
response to woundingGO:00096112540.126
response to growth factorGO:00708481890.123
carboxylic acid metabolic processGO:00197522890.123
positive regulation of developmental processGO:00510942830.122
positive regulation of phosphorus metabolic processGO:00105622620.121
regulation of transcription dna templatedGO:00063553740.120
negative regulation of multicellular organismal processGO:00512412030.117
regulation of axonogenesisGO:0050770370.114
regulation of nucleic acid templated transcriptionGO:19035063800.114
reproductive processGO:00224143720.113
regulation of ion transportGO:00432692450.112
monosaccharide metabolic processGO:0005996610.112
regulation of metal ion transportGO:00109591180.110
localization of cellGO:00516742020.108
cell cell signalingGO:00072673350.106
cell adhesionGO:00071551100.106
regulation of intracellular signal transductionGO:19025312180.106
endocytosisGO:0006897840.103
positive regulation of rna biosynthetic processGO:19026801970.102
positive regulation of transportGO:00510502450.101
negative regulation of cell communicationGO:00106481580.100
developmental growthGO:00485891000.099
dendrite developmentGO:0016358720.098
oxoacid metabolic processGO:00434362900.098
regulation of phosphorus metabolic processGO:00511743490.098
cell morphogenesisGO:00009021420.097
positive regulation of transcription dna templatedGO:00458931970.097
positive regulation of nitrogen compound metabolic processGO:00511733340.097
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.096
response to extracellular stimulusGO:00099913800.096
regulation of molecular functionGO:00650093980.096
regulation of apoptotic processGO:00429813350.095
response to corticosteroidGO:00319602350.095
forebrain developmentGO:0030900980.094
circulatory system developmentGO:00723591340.094
single organism reproductive processGO:00447022970.093
response to nutrient levelsGO:00316673700.093
lipid metabolic processGO:00066292830.092
regulation of catalytic activityGO:00507903040.092
regulation of cellular protein metabolic processGO:00322682670.091
regulation of phosphorylationGO:00423252480.091
rna metabolic processGO:00160704060.091
transcription dna templatedGO:00063513770.090
negative regulation of cell deathGO:00605482290.090
negative regulation of metabolic processGO:00098923310.090
cell migrationGO:00164771970.090
positive regulation of neurogenesisGO:00507691650.089
negative regulation of programmed cell deathGO:00430691830.088
regulation of cellular component movementGO:00512701500.088
regulation of rna metabolic processGO:00512523910.087
positive regulation of cell differentiationGO:00455972170.086
regulation of anatomical structure sizeGO:00900661350.086
secretion by cellGO:00329402480.085
cellular response to hormone stimulusGO:00328702470.085
positive regulation of cellular component organizationGO:00511302000.084
positive regulation of phosphate metabolic processGO:00459372620.084
gland developmentGO:00487321550.083
positive regulation of cell proliferationGO:00082842490.083
gliogenesisGO:0042063930.083
protein localizationGO:00081041910.082
wound healingGO:00420601220.081
regulation of protein modification processGO:00313991940.080
organelle organizationGO:00069962660.080
divalent inorganic cation transportGO:00725111340.079
positive regulation of catalytic activityGO:00430851840.079
regulation of locomotionGO:00400121480.078
response to peptide hormoneGO:00434342780.078
macromolecular complex subunit organizationGO:00439333390.077
cellular response to endogenous stimulusGO:00714953770.077
actin filament based processGO:0030029860.076
sensory perception of painGO:0019233730.076
response to amino acidGO:0043200750.075
neuron projection guidanceGO:0097485240.073
multi organism reproductive processGO:00447032620.073
response to cytokineGO:00340972150.073
peptidyl amino acid modificationGO:00181931260.072
peptidyl tyrosine phosphorylationGO:0018108720.071
hexose metabolic processGO:0019318580.071
regulation of cell proliferationGO:00421273590.071
nitrogen compound transportGO:00717052290.070
regulation of cell morphogenesisGO:0022604770.070
neurological system processGO:00508772190.069
positive regulation of nucleic acid templated transcriptionGO:19035081970.069
regulation of system processGO:00440572080.069
synaptic transmissionGO:00072682350.068
sensory perceptionGO:00076001010.067
purine ribonucleotide metabolic processGO:00091502270.067
positive regulation of signalingGO:00230562700.067
regulation of mapk cascadeGO:00434081160.066
positive regulation of neuron projection developmentGO:0010976990.065
nucleotide metabolic processGO:00091172790.065
regulation of secretionGO:00510462240.065
single organism cell adhesionGO:0098602460.064
response to nutrientGO:00075842480.064
regulation of cell projection organizationGO:00313441750.063
negative regulation of cellular metabolic processGO:00313242810.063
nucleobase containing small molecule metabolic processGO:00550863160.063
ras protein signal transductionGO:0007265290.063
negative regulation of growthGO:0045926370.062
regenerationGO:00310991630.062
response to external biotic stimulusGO:00432072210.062
appendage morphogenesisGO:003510740.062
response to insulinGO:00328681330.061
cellular ketone metabolic processGO:0042180510.061
rna biosynthetic processGO:00327743800.061
negative regulation of apoptotic processGO:00430661810.060
regulation of programmed cell deathGO:00430673410.060
positive regulation of molecular functionGO:00440932300.060
positive regulation of signal transductionGO:00099671750.059
regulation of protein phosphorylationGO:00019321830.059
positive regulation of rna metabolic processGO:00512542030.059
regulation of cell migrationGO:00303341280.058
regulation of cellular ketone metabolic processGO:0010565270.058
salivary gland morphogenesisGO:000743510.058
negative regulation of signalingGO:00230571570.057
cellular response to oxygen containing compoundGO:19017013860.057
cellular response to peptideGO:19016531330.057
ion transmembrane transportGO:00342203650.056
regulation of secretion by cellGO:19035302080.056
nucleic acid templated transcriptionGO:00976593790.056
epidermal growth factor receptor signaling pathwayGO:0007173230.055
protein transportGO:00150311320.055
behaviorGO:00076102050.054
regulation of hydrolase activityGO:00513361430.054
protein autophosphorylationGO:0046777660.054
actin cytoskeleton organizationGO:0030036730.054
regulation of neuron deathGO:19012141150.054
response to inorganic substanceGO:00100353770.053
regulation of cellular localizationGO:00603412630.053
response to ketoneGO:19016541820.052
positive regulation of phosphorylationGO:00423271770.052
positive regulation of cellular biosynthetic processGO:00313282950.052
sexual reproductionGO:00199531480.052
regulation of cell motilityGO:20001451310.052
salivary gland developmentGO:000743130.051
cellular response to nitrogen compoundGO:19016992100.051
regulation of catabolic processGO:00098941130.051
response to oxygen levelsGO:00704822650.051
nucleotide catabolic processGO:00091661390.051
phospholipid metabolic processGO:0006644610.051
cardiovascular system developmentGO:00723581340.050
single organism cellular localizationGO:19025801020.050
cellular cation homeostasisGO:00300031800.050
response to glucocorticoidGO:00513842230.050
cellular response to lipidGO:00713962010.050
small gtpase mediated signal transductionGO:0007264360.049
cellular divalent inorganic cation homeostasisGO:00725031620.049
positive regulation of locomotionGO:00400171020.049
ribonucleotide metabolic processGO:00092592310.049
amine metabolic processGO:0009308380.049
response to carbohydrateGO:00097431830.048
cognitionGO:0050890920.048
carbohydrate derivative metabolic processGO:19011353460.048
single organism intracellular transportGO:19025821660.048
positive regulation of intracellular signal transductionGO:19025331380.048
positive regulation of neuron differentiationGO:00456661260.047
organophosphate catabolic processGO:00464341480.047
positive regulation of cell projection organizationGO:00313461110.047
chemical homeostasisGO:00488782920.047
protein phosphorylationGO:00064683450.047
cellular response to growth factor stimulusGO:00713631620.047
single organism biosynthetic processGO:00447113420.047
peptidyl tyrosine modificationGO:0018212720.047
regulation of growthGO:00400081050.046
negative regulation of nervous system developmentGO:0051961790.046
purine containing compound metabolic processGO:00725212530.046
reproductionGO:00000032450.046
positive regulation of secretionGO:00510471400.046
calcium ion transportGO:00068161310.046
regulation of nucleotide metabolic processGO:00061401170.046
learning or memoryGO:0007611900.045
secretionGO:00469033070.045
protein complex biogenesisGO:00702712630.045
cellular chemical homeostasisGO:00550822470.045
negative regulation of cellular component organizationGO:0051129830.045
cellular carbohydrate metabolic processGO:0044262720.045
ribonucleoside metabolic processGO:00091191740.045
negative regulation of developmental processGO:00510931250.044
erbb signaling pathwayGO:0038127230.044
regulation of lipid metabolic processGO:0019216680.044
mitotic cell cycle processGO:1903047350.044
regulation of cell morphogenesis involved in differentiationGO:0010769720.044
regulation of cellular amine metabolic processGO:003323880.044
agingGO:00075682410.043
negative regulation of response to stimulusGO:00485851550.043
glycosyl compound metabolic processGO:19016571820.043
cation transportGO:00068123820.042
ribonucleoside triphosphate catabolic processGO:00092031220.042
cellular response to stressGO:00335542690.042
nucleoside phosphate metabolic processGO:00067532830.042
nucleoside triphosphate catabolic processGO:00091431230.042
organic substance catabolic processGO:19015753160.042
cellular metal ion homeostasisGO:00068751720.042
response to peptideGO:19016522920.042
response to estrogenGO:00436272320.042
response to axon injuryGO:0048678590.042
positive regulation of cell developmentGO:00107201760.042
purine ribonucleoside catabolic processGO:00461301240.041
regulation of kinase activityGO:00435491170.040
response to temperature stimulusGO:0009266940.040
cellular response to organonitrogen compoundGO:00714171970.040
cellular amine metabolic processGO:0044106380.040
purine nucleoside triphosphate metabolic processGO:00091441410.040
cellular macromolecule localizationGO:00707271220.040
maintenance of locationGO:0051235170.040
cellular response to lipopolysaccharideGO:0071222550.040
cytoskeleton organizationGO:00070101110.040
formation of primary germ layerGO:000170410.040
transmembrane transportGO:00550854120.040
positive regulation of protein phosphorylationGO:00019341350.040
regulation of cellular component biogenesisGO:0044087860.039
regulation of cellular amino acid metabolic processGO:000652120.039
cell growthGO:00160491040.039
positive regulation of protein modification processGO:00314011420.039
response to acid chemicalGO:00011012220.039
sensory organ developmentGO:0007423740.039
response to estradiolGO:00323551640.038
intracellular transportGO:00469071850.038
purine ribonucleoside metabolic processGO:00461281680.038
positive regulation of gtpase activityGO:0043547470.038
gamete generationGO:00072761240.038
cell type specific apoptotic processGO:00972851340.038
cellular amino acid metabolic processGO:00065201070.037
negative regulation of gene expressionGO:00106291990.037
limb morphogenesisGO:003510840.037
negative regulation of protein metabolic processGO:00512481140.037
transcription from rna polymerase ii promoterGO:00063662520.037
gastrulationGO:000736920.037
ribose phosphate metabolic processGO:00196932350.037
purine nucleotide metabolic processGO:00061632290.037
regulation of transmembrane transportGO:00347621220.037
positive regulation of purine nucleotide metabolic processGO:1900544910.037
muscle structure developmentGO:0061061870.037
anatomical structure formation involved in morphogenesisGO:0048646830.037
fatty acid metabolic processGO:0006631990.036
response to biotic stimulusGO:00096072260.036
nucleoside catabolic processGO:00091641260.036
epithelium developmentGO:0060429960.036
macromolecular complex assemblyGO:00650032730.036
response to ethanolGO:00454711620.036
negative regulation of signal transductionGO:0009968830.036
positive regulation of nucleotide metabolic processGO:0045981910.035
regulation of developmental growthGO:0048638450.035
glucose metabolic processGO:0006006520.035
regulation of purine nucleotide metabolic processGO:19005421150.035
spindle organizationGO:000705120.035
regulation of homeostatic processGO:00328441010.035
motor neuron axon guidanceGO:000804510.035
single organism membrane organizationGO:0044802740.035
single organism behaviorGO:00447081300.035
positive regulation of response to stimulusGO:00485842850.034
signal transduction by phosphorylationGO:00230141440.034
regulation of vesicle mediated transportGO:0060627810.034
heterocycle catabolic processGO:00467001670.034
positive regulation of cellular amine metabolic processGO:003324030.034
cation homeostasisGO:00550801950.034
cellular calcium ion homeostasisGO:00068741600.034
dendrite morphogenesisGO:0048813430.034
regulation of protein kinase activityGO:00458591050.034
nucleoside phosphate catabolic processGO:19012921400.034
cellular protein localizationGO:00346131220.034
negative regulation of neuron differentiationGO:0045665620.034
proteolysisGO:00065081750.033
metal ion transportGO:00300012890.033
membrane organizationGO:0061024940.033
response to oxidative stressGO:00069791860.033
multicellular organism reproductionGO:00325042330.033
muscle system processGO:00030121150.032
cell cycleGO:00070491010.032
glial cell differentiationGO:0010001650.032
signal releaseGO:00230611450.032
divalent metal ion transportGO:00708381320.032
apoptotic signaling pathwayGO:0097190270.032
embryonic appendage morphogenesisGO:003511340.031
regulation of calcium ion transportGO:0051924770.031
muscle cell differentiationGO:0042692520.031
positive regulation of protein metabolic processGO:00512471780.031
positive regulation of cellular amino acid metabolic processGO:004576410.031
regulation of transcription from rna polymerase ii promoterGO:00063572340.031
cellular response to insulin stimulusGO:0032869810.031
immune system processGO:00023762040.031
positive regulation of cellular protein metabolic processGO:00322701670.031
protein complex assemblyGO:00064612630.031
metal ion homeostasisGO:00550651860.031
cellular ion homeostasisGO:00068731840.031
taxisGO:0042330670.030
regulation of hormone levelsGO:00108171870.030
positive regulation of lipid kinase activityGO:009021820.030
regulation of proteasomal protein catabolic processGO:006113640.030
cytosolic calcium ion homeostasisGO:00514801400.030
glycosyl compound catabolic processGO:19016581260.030
ion homeostasisGO:00508012120.030
mitotic spindle organizationGO:000705220.030
response to transforming growth factor betaGO:0071559460.030
monovalent inorganic cation transportGO:00156721720.030
negative regulation of rna metabolic processGO:00512531230.030
positive regulation of cellular component movementGO:00512721020.029
regulation of synapse organizationGO:0050807190.029
multicellular organismal reproductive processGO:00486092330.029
cellular response to steroid hormone stimulusGO:0071383930.029
calcium ion homeostasisGO:00550741620.029
homeostatic processGO:00425923310.029
negative regulation of cell differentiationGO:0045596990.029
negative regulation of cellular biosynthetic processGO:00313271610.029
mapk cascadeGO:00001651400.029
sex differentiationGO:00075481130.029
response to decreased oxygen levelsGO:00362932370.029
cardiac chamber developmentGO:000320510.029
protein maturationGO:0051604680.028
regulation of transferase activityGO:00513381230.028
response to mechanical stimulusGO:00096121340.028
regulation of membrane potentialGO:00423911100.028
negative regulation of macromolecule metabolic processGO:00106052600.028
gonad developmentGO:00084061040.028
positive regulation of cell motilityGO:2000147970.028
circulatory system processGO:00030131830.028
positive regulation of secretion by cellGO:19035321280.027
regulation of platelet derived growth factor receptor signaling pathwayGO:001064020.027
defense responseGO:00069521940.027
heart morphogenesisGO:000300730.027
positive regulation of cellular component biogenesisGO:0044089550.027
regulation of cell cycleGO:0051726730.027
monocarboxylic acid metabolic processGO:00327871520.027
positive regulation of programmed cell deathGO:00430681570.027
ribonucleotide catabolic processGO:00092611360.027
purine ribonucleotide catabolic processGO:00091541360.027
negative regulation of neurogenesisGO:0050768780.027
regulation of cell growthGO:0001558850.027
negative regulation of neuron deathGO:1901215690.027
regulation of protein metabolic processGO:00512462890.026
response to toxic substanceGO:00096361330.026
positive regulation of cell migrationGO:0030335960.026
response to lipopolysaccharideGO:00324961910.026
organic cyclic compound catabolic processGO:19013611750.026
organelle localizationGO:0051640550.026
ribonucleoside triphosphate metabolic processGO:00091991410.026
regulation of ras gtpase activityGO:0032318320.026
nucleobase containing compound catabolic processGO:00346551520.026
development of primary sexual characteristicsGO:00451371070.025
purine nucleoside metabolic processGO:00422781690.025
response to reactive oxygen speciesGO:00003021200.025
regulation of synapse structure and activityGO:0050803210.025
positive regulation of protein kinase activityGO:0045860730.025
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.025
response to bacteriumGO:00096172000.025
exocytosisGO:0006887600.025
chemotaxisGO:0006935660.025
tube developmentGO:0035295890.025
regulation of cell adhesionGO:0030155520.025
regulation of ion transmembrane transportGO:00347651210.025
neuromuscular processGO:005090520.025
eye developmentGO:0001654500.025
hormone transportGO:00099141210.024
regulation of synaptic transmissionGO:00508041410.024
organophosphate biosynthetic processGO:00904071430.024
developmental process involved in reproductionGO:00030061590.024
positive regulation of cytosolic calcium ion concentrationGO:00072041220.024
regulation of small gtpase mediated signal transductionGO:0051056480.024
regulation of neural precursor cell proliferationGO:2000177160.024
glycerolipid metabolic processGO:0046486670.024
muscle cell proliferationGO:0033002840.024
sequestering of calcium ionGO:005120880.024
cellular response to organic cyclic compoundGO:00714072020.024
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.024
response to hexoseGO:00097461440.023
response to other organismGO:00517072200.023
eye morphogenesisGO:004859240.023
positive regulation of ion transportGO:0043270940.023
negative regulation of cell developmentGO:0010721820.023
cellular response to biotic stimulusGO:0071216590.023
gtp metabolic processGO:0046039720.023
response to hypoxiaGO:00016662310.023
reproductive structure developmentGO:00486081280.023
cellular response to acid chemicalGO:0071229750.023
blood vessel morphogenesisGO:0048514580.023
cellular response to peptide hormone stimulusGO:00713751200.023
negative regulation of peptidase activityGO:0010466380.023
cellular homeostasisGO:00197252520.023
muscle tissue developmentGO:0060537580.023
hormone secretionGO:00468791150.023
positive regulation of apoptotic processGO:00430651540.023
positive regulation of nucleoside metabolic processGO:0045979550.023
striated muscle tissue developmentGO:0014706580.022
cellular nitrogen compound catabolic processGO:00442701630.022
chromosome segregationGO:000705920.022
cellular response to molecule of bacterial originGO:0071219560.022
regulation of cellular component sizeGO:0032535510.022
regulation of gtpase activityGO:0043087570.022
insulin receptor signaling pathwayGO:0008286240.022
response to molecule of bacterial originGO:00022371940.022
g protein coupled receptor signaling pathwayGO:00071862420.022
protein targetingGO:0006605610.022
establishment of organelle localizationGO:0051656370.022
aromatic compound catabolic processGO:00194391680.022
regulation of immune system processGO:00026821230.022
cellular response to external stimulusGO:00714961180.022
peptide transportGO:0015833970.022
muscle organ developmentGO:0007517500.022
negative regulation of nitrogen compound metabolic processGO:00511721610.022
negative regulation of neuron apoptotic processGO:0043524450.022
regulation of muscle system processGO:0090257790.022
positive regulation of hydrolase activityGO:0051345860.022
tissue regenerationGO:0042246360.021
carbohydrate derivative catabolic processGO:19011361470.021
organic hydroxy compound transportGO:0015850770.021
positive regulation of mapk cascadeGO:0043410920.021
negative regulation of biosynthetic processGO:00098901680.021
response to fatty acidGO:0070542650.021
cell activationGO:0001775970.021
immune responseGO:00069551040.021
positive regulation of cell deathGO:00109421840.021
divalent inorganic cation homeostasisGO:00725071650.021
regulation of carbohydrate metabolic processGO:0006109410.021
negative regulation of macromolecule biosynthetic processGO:00105581480.021
positive regulation of transferase activityGO:0051347810.021
regulation of protein maturationGO:1903317500.021
purine ribonucleoside triphosphate metabolic processGO:00092051400.021
protein localization to membraneGO:0072657360.021
cell fate determinationGO:000170920.020
regulation of protein localizationGO:0032880810.020
tangential migration from the subventricular zone to the olfactory bulbGO:002202810.020
response to radiationGO:00093141370.020
purine nucleoside catabolic processGO:00061521240.020
morphogenesis of an epitheliumGO:0002009200.020
t cell receptor signaling pathwayGO:005085210.020

Ptprs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.051
disease of anatomical entityDOID:700.051
nervous system diseaseDOID:86300.032
connective tissue diseaseDOID:6500.028
central nervous system diseaseDOID:33100.026
disease of metabolismDOID:001466700.022
brain diseaseDOID:93600.020