Rattus norvegicus

104 known processes

Dhodh

dihydroorotate dehydrogenase

Dhodh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular protein metabolic processGO:00322682670.179
oxoacid metabolic processGO:00434362900.150
organic acid metabolic processGO:00060822920.115
nucleobase containing small molecule metabolic processGO:00550863160.113
regulation of phosphorylationGO:00423252480.108
positive regulation of phosphate metabolic processGO:00459372620.104
protein phosphorylationGO:00064683450.103
regulation of protein metabolic processGO:00512462890.103
programmed cell deathGO:00125013920.098
regulation of phosphorus metabolic processGO:00511743490.096
regulation of catalytic activityGO:00507903040.094
positive regulation of apoptotic processGO:00430651540.086
nucleotide metabolic processGO:00091172790.084
amine metabolic processGO:0009308380.084
positive regulation of phosphorus metabolic processGO:00105622620.084
response to cytokineGO:00340972150.080
intracellular signal transductionGO:00355563140.080
positive regulation of signalingGO:00230562700.079
negative regulation of cellular metabolic processGO:00313242810.077
carboxylic acid metabolic processGO:00197522890.072
apoptotic processGO:00069153810.070
positive regulation of nitrogen compound metabolic processGO:00511733340.069
nucleoside phosphate metabolic processGO:00067532830.069
regulation of cell proliferationGO:00421273590.069
response to radiationGO:00093141370.069
negative regulation of gene expressionGO:00106291990.064
central nervous system developmentGO:00074173110.063
negative regulation of metabolic processGO:00098923310.063
regulation of molecular functionGO:00650093980.063
single organism biosynthetic processGO:00447113420.061
negative regulation of cell deathGO:00605482290.061
organelle organizationGO:00069962660.060
response to nutrientGO:00075842480.059
positive regulation of nucleic acid templated transcriptionGO:19035081970.059
positive regulation of cell proliferationGO:00082842490.057
response to inorganic substanceGO:00100353770.057
response to nutrient levelsGO:00316673700.056
cellular component assemblyGO:00226073600.056
positive regulation of nucleobase containing compound metabolic processGO:00459353190.055
macromolecular complex assemblyGO:00650032730.055
regulation of protein phosphorylationGO:00019321830.055
cellular response to stressGO:00335542690.054
single organism organelle organizationGO:19025891800.053
response to woundingGO:00096112540.052
cellular component biogenesisGO:00440853680.052
rna metabolic processGO:00160704060.052
positive regulation of molecular functionGO:00440932300.050
positive regulation of cellular biosynthetic processGO:00313282950.050
response to metal ionGO:00100382530.049
positive regulation of catalytic activityGO:00430851840.047
response to extracellular stimulusGO:00099913800.047
regulation of kinase activityGO:00435491170.046
regulation of programmed cell deathGO:00430673410.046
rhythmic processGO:00485111560.045
cellular response to endogenous stimulusGO:00714953770.045
response to glucocorticoidGO:00513842230.045
negative regulation of macromolecule metabolic processGO:00106052600.044
positive regulation of secretionGO:00510471400.044
carbohydrate derivative metabolic processGO:19011353460.044
cellular amino acid metabolic processGO:00065201070.044
transcription dna templatedGO:00063513770.043
regulation of cellular amine metabolic processGO:003323880.043
positive regulation of biosynthetic processGO:00098913190.043
regulation of multicellular organismal developmentGO:20000263760.043
catabolic processGO:00090563510.042
regulation of phosphate metabolic processGO:00192203490.042
tissue developmentGO:00098882520.042
transcription from rna polymerase ii promoterGO:00063662520.041
regulation of apoptotic processGO:00429813350.041
cellular catabolic processGO:00442482950.040
regulation of transferase activityGO:00513381230.040
regulation of cell differentiationGO:00455953200.040
cellular response to oxygen containing compoundGO:19017013860.040
reproductive processGO:00224143720.040
negative regulation of programmed cell deathGO:00430691830.039
negative regulation of molecular functionGO:00440921330.039
negative regulation of cellular protein metabolic processGO:00322691060.038
organonitrogen compound biosynthetic processGO:19015661670.038
mapk cascadeGO:00001651400.038
positive regulation of response to stimulusGO:00485842850.038
reproductionGO:00000032450.038
macromolecular complex subunit organizationGO:00439333390.038
regulation of cellular component organizationGO:00511283680.037
response to oxidative stressGO:00069791860.037
positive regulation of protein metabolic processGO:00512471780.036
positive regulation of phosphorylationGO:00423271770.036
negative regulation of cellular biosynthetic processGO:00313271610.036
nucleic acid templated transcriptionGO:00976593790.036
cellular amine metabolic processGO:0044106380.035
protein complex subunit organizationGO:00718223020.035
positive regulation of cell communicationGO:00106472710.035
positive regulation of transferase activityGO:0051347810.035
cellular response to lipidGO:00713962010.035
purine ribonucleotide metabolic processGO:00091502270.035
ribose phosphate metabolic processGO:00196932350.034
ribonucleotide metabolic processGO:00092592310.034
regulation of protein kinase activityGO:00458591050.034
multicellular organismal reproductive processGO:00486092330.034
positive regulation of multicellular organismal processGO:00512403870.034
regulation of intracellular signal transductionGO:19025312180.034
lipid metabolic processGO:00066292830.034
response to purine containing compoundGO:00140741260.034
regulation of cellular amino acid metabolic processGO:000652120.033
coenzyme metabolic processGO:0006732860.033
response to hypoxiaGO:00016662310.033
regulation of rna metabolic processGO:00512523910.032
proteolysisGO:00065081750.031
cofactor metabolic processGO:0051186950.031
organophosphate metabolic processGO:00196373700.031
protein complex assemblyGO:00064612630.031
multicellular organism reproductionGO:00325042330.031
regulation of transcription from rna polymerase ii promoterGO:00063572340.031
response to alkaloidGO:00432791320.031
organic substance catabolic processGO:19015753160.031
positive regulation of transcription dna templatedGO:00458931970.031
negative regulation of nucleobase containing compound metabolic processGO:00459341530.030
response to peptide hormoneGO:00434342780.030
negative regulation of protein metabolic processGO:00512481140.030
regulation of nervous system developmentGO:00519602640.030
positive regulation of cell deathGO:00109421840.030
negative regulation of apoptotic processGO:00430661810.029
negative regulation of cell proliferationGO:00082851190.029
single organism catabolic processGO:00447122830.029
regulation of mapk cascadeGO:00434081160.029
brain developmentGO:00074202470.029
circulatory system processGO:00030131830.029
single organism reproductive processGO:00447022970.029
rna biosynthetic processGO:00327743800.029
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.029
positive regulation of cellular protein metabolic processGO:00322701670.029
response to transition metal nanoparticleGO:19902671220.028
cellular ketone metabolic processGO:0042180510.028
cell projection organizationGO:00300303020.028
purine containing compound metabolic processGO:00725212530.028
response to oxygen levelsGO:00704822650.028
response to corticosteroidGO:00319602350.028
carbohydrate derivative biosynthetic processGO:19011371240.028
nucleotide biosynthetic processGO:0009165980.028
response to amino acidGO:0043200750.027
positive regulation of kinase activityGO:0033674770.027
positive regulation of protein phosphorylationGO:00019341350.027
positive regulation of programmed cell deathGO:00430681570.027
regulation of locomotionGO:00400121480.027
response to decreased oxygen levelsGO:00362932370.027
growthGO:00400071650.027
signal transduction by phosphorylationGO:00230141440.027
response to ethanolGO:00454711620.027
regulation of rna biosynthetic processGO:20011413810.026
response to growth factorGO:00708481890.026
regulation of protein modification processGO:00313991940.026
dna metabolic processGO:0006259960.026
cellular response to cytokine stimulusGO:00713451270.026
organophosphate biosynthetic processGO:00904071430.026
positive regulation of transportGO:00510502450.026
nucleoside phosphate biosynthetic processGO:19012931020.026
response to campGO:0051591910.026
cellular component movementGO:00069282480.025
purine nucleotide metabolic processGO:00061632290.025
tube developmentGO:0035295890.025
regulation of cellular ketone metabolic processGO:0010565270.025
protein localizationGO:00081041910.025
positive regulation of cellular component organizationGO:00511302000.025
developmental process involved in reproductionGO:00030061590.025
organ regenerationGO:00311001010.025
regulation of transcription dna templatedGO:00063553740.025
regenerationGO:00310991630.024
response to reactive oxygen speciesGO:00003021200.024
cellular response to organic cyclic compoundGO:00714072020.024
regulation of nucleotide metabolic processGO:00061401170.024
regulation of system processGO:00440572080.024
response to peptideGO:19016522920.024
nucleoside metabolic processGO:00091161790.024
regulation of cell developmentGO:00602842630.023
negative regulation of nucleic acid templated transcriptionGO:19035071170.023
protein maturationGO:0051604680.023
positive regulation of cellular amine metabolic processGO:003324030.023
positive regulation of rna metabolic processGO:00512542030.023
intracellular transportGO:00469071850.023
response to vitaminGO:00332731310.023
response to molecule of bacterial originGO:00022371940.022
g protein coupled receptor signaling pathwayGO:00071862420.022
response to organophosphorusGO:00466831020.022
regulation of cell motilityGO:20001451310.022
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.022
localization of cellGO:00516742020.022
positive regulation of signal transductionGO:00099671750.022
cellular cation homeostasisGO:00300031800.021
cellular homeostasisGO:00197252520.021
cellular response to hormone stimulusGO:00328702470.021
head developmentGO:00603222470.021
negative regulation of transcription dna templatedGO:00458921160.021
organonitrogen compound catabolic processGO:19015651790.021
negative regulation of biosynthetic processGO:00098901680.021
secretionGO:00469033070.021
cellular lipid metabolic processGO:00442552080.021
macromolecule localizationGO:00330362520.021
positive regulation of protein modification processGO:00314011420.021
cell cell signalingGO:00072673350.021
cellular ion homeostasisGO:00068731840.020
regulation of signal transductionGO:00099663180.020
cell type specific apoptotic processGO:00972851340.020
negative regulation of cellular component organizationGO:0051129830.020
carboxylic acid transportGO:00469421150.020
positive regulation of mapk cascadeGO:0043410920.020
cellular component morphogenesisGO:00329891550.020
ribose phosphate biosynthetic processGO:0046390870.020
positive regulation of intracellular signal transductionGO:19025331380.020
regulation of nucleic acid templated transcriptionGO:19035063800.020
locomotionGO:00400112370.019
nucleobase containing compound catabolic processGO:00346551520.019
agingGO:00075682410.019
negative regulation of signalingGO:00230571570.019
regulation of membrane potentialGO:00423911100.019
negative regulation of rna biosynthetic processGO:19026791180.019
regulation of neuron deathGO:19012141150.019
regulation of cellular localizationGO:00603412630.019
negative regulation of cell communicationGO:00106481580.019
protein oligomerizationGO:00512591910.019
response to monosaccharideGO:00342841590.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
negative regulation of signal transductionGO:0009968830.019
metal ion transportGO:00300012890.019
alpha amino acid metabolic processGO:1901605710.018
response to glucoseGO:00097491360.018
reproductive system developmentGO:00614581280.018
protein processingGO:0016485680.018
cellular chemical homeostasisGO:00550822470.018
immune system processGO:00023762040.018
oxidation reduction processGO:00551143040.018
negative regulation of rna metabolic processGO:00512531230.018
ribonucleoside metabolic processGO:00091191740.018
purine nucleoside metabolic processGO:00422781690.018
neuron deathGO:00709971270.018
sensory organ developmentGO:0007423740.018
protein complex biogenesisGO:00702712630.018
peptidyl amino acid modificationGO:00181931260.018
response to carbohydrateGO:00097431830.018
cyclic nucleotide metabolic processGO:0009187800.017
response to external biotic stimulusGO:00432072210.017
regulation of neurogenesisGO:00507672470.017
response to lipopolysaccharideGO:00324961910.017
regulation of neuron projection developmentGO:00109751610.017
establishment of protein localizationGO:00451841410.017
positive regulation of developmental processGO:00510942830.017
ovulation cycleGO:0042698670.017
regulation of cell cycleGO:0051726730.017
homeostatic processGO:00425923310.017
neurological system processGO:00508772190.017
regulation of hormone levelsGO:00108171870.017
neuron differentiationGO:00301823680.017
regulation of cell migrationGO:00303341280.017
response to other organismGO:00517072200.017
glycosyl compound metabolic processGO:19016571820.017
regulation of cellular component movementGO:00512701500.017
cytoplasmic transportGO:00164821150.017
regulation of cell projection organizationGO:00313441750.016
cell migrationGO:00164771970.016
neuron developmentGO:00486662860.016
response to hexoseGO:00097461440.016
ribonucleotide biosynthetic processGO:0009260850.016
cell morphogenesisGO:00009021420.016
gliogenesisGO:0042063930.016
glial cell differentiationGO:0010001650.016
sulfur compound metabolic processGO:0006790700.016
cellular metal ion homeostasisGO:00068751720.016
regulation of map kinase activityGO:0043405530.016
negative regulation of cell cycle phase transitionGO:190198840.016
multi multicellular organism processGO:00447061380.016
peptidyl tyrosine phosphorylationGO:0018108720.016
aromatic compound catabolic processGO:00194391680.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
response to estrogenGO:00436272320.016
response to bacteriumGO:00096172000.016
multi organism reproductive processGO:00447032620.016
regulation of purine nucleotide metabolic processGO:19005421150.016
response to hydrogen peroxideGO:0042542890.016
carboxylic acid biosynthetic processGO:0046394830.016
divalent inorganic cation homeostasisGO:00725071650.016
biological adhesionGO:00226101100.016
negative regulation of transportGO:00510511360.015
sex differentiationGO:00075481130.015
cell motilityGO:00488702020.015
jak stat cascadeGO:0007259260.015
cellular nitrogen compound catabolic processGO:00442701630.015
renal system developmentGO:0072001670.015
synaptic transmissionGO:00072682350.015
peptidyl tyrosine modificationGO:0018212720.015
developmental growthGO:00485891000.015
purine containing compound catabolic processGO:00725231380.015
metal ion homeostasisGO:00550651860.015
blood circulationGO:00080151830.015
single organism intracellular transportGO:19025821660.015
regulation of smooth muscle cell proliferationGO:0048660750.015
regulation of protein localizationGO:0032880810.015
epithelial cell differentiationGO:0030855710.015
response to acid chemicalGO:00011012220.015
ras protein signal transductionGO:0007265290.015
positive regulation of protein kinase activityGO:0045860730.015
cellular response to nitrogen compoundGO:19016992100.015
regulation of cellular component biogenesisGO:0044087860.015
negative regulation of macromolecule biosynthetic processGO:00105581480.014
chromosome organizationGO:0051276360.014
cellular macromolecule localizationGO:00707271220.014
chemical homeostasisGO:00488782920.014
purine ribonucleotide biosynthetic processGO:0009152810.014
regulation of neuron differentiationGO:00456642080.014
cyclic purine nucleotide metabolic processGO:0052652620.014
regulation of secretionGO:00510462240.014
axis specificationGO:000979840.014
hormone secretionGO:00468791150.014
cellular response to organonitrogen compoundGO:00714171970.014
negative regulation of mitotic cell cycle phase transitionGO:190199130.014
nitrogen compound transportGO:00717052290.014
organic cyclic compound catabolic processGO:19013611750.014
negative regulation of multicellular organismal processGO:00512412030.014
epithelium developmentGO:0060429960.014
nucleotide catabolic processGO:00091661390.014
ion homeostasisGO:00508012120.014
gastrulationGO:000736920.014
heart morphogenesisGO:000300730.014
response to light stimulusGO:0009416520.014
circulatory system developmentGO:00723591340.014
chromosome segregationGO:000705920.014
calcium ion homeostasisGO:00550741620.014
purine ribonucleotide catabolic processGO:00091541360.014
positive regulation of nucleotide metabolic processGO:0045981910.014
negative regulation of response to stimulusGO:00485851550.013
signal releaseGO:00230611450.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
reactive oxygen species biosynthetic processGO:190340980.013
positive regulation of cell developmentGO:00107201760.013
regulation of camp biosynthetic processGO:0030817380.013
organic anion transportGO:00157111320.013
regulation of cyclic nucleotide metabolic processGO:0030799510.013
response to ketoneGO:19016541820.013
activation of protein kinase activityGO:0032147470.013
positive regulation of gene expressionGO:00106282440.013
cell cycleGO:00070491010.013
carbohydrate derivative catabolic processGO:19011361470.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
monocarboxylic acid metabolic processGO:00327871520.013
cell adhesionGO:00071551100.013
cellular response to growth factor stimulusGO:00713631620.013
negative regulation of cell divisionGO:005178210.013
negative regulation of cell differentiationGO:0045596990.013
sexual reproductionGO:00199531480.012
purine ribonucleoside catabolic processGO:00461301240.012
positive regulation of secretion by cellGO:19035321280.012
embryonic skeletal system morphogenesisGO:004870430.012
small gtpase mediated signal transductionGO:0007264360.012
purine containing compound biosynthetic processGO:0072522850.012
camera type eye developmentGO:0043010480.012
cell morphogenesis involved in differentiationGO:00009041190.012
regulation of ion transportGO:00432692450.012
single organism membrane organizationGO:0044802740.012
camp biosynthetic processGO:0006171470.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
regulation of hydrolase activityGO:00513361430.012
response to amineGO:0014075460.012
regulation of anatomical structure sizeGO:00900661350.012
heterocycle catabolic processGO:00467001670.012
negative regulation of developmental processGO:00510931250.012
positive regulation of cell differentiationGO:00455972170.012
regulation of anion transportGO:0044070430.012
single organism cellular localizationGO:19025801020.012
negative regulation of nuclear divisionGO:005178410.012
cell cycle checkpointGO:000007520.012
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.012
cytosolic calcium ion homeostasisGO:00514801400.012
reproductive structure developmentGO:00486081280.012
transmembrane transportGO:00550854120.011
wound healingGO:00420601220.011
purine ribonucleoside metabolic processGO:00461281680.011
gland developmentGO:00487321550.011
regulation of cellular catabolic processGO:00313291010.011
neuron projection developmentGO:00311752730.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
positive regulation of nervous system developmentGO:00519621780.011
nucleoside catabolic processGO:00091641260.011
cellular response to oxygen levelsGO:0071453600.011
ribonucleoside catabolic processGO:00424541260.011
positive regulation of catabolic processGO:0009896780.011
smooth muscle cell proliferationGO:0048659770.011
protein transportGO:00150311320.011
development of primary female sexual characteristicsGO:0046545560.011
mitotic cell cycle checkpointGO:000709310.011
development of primary sexual characteristicsGO:00451371070.011
negative regulation of phosphorus metabolic processGO:0010563800.011
positive regulation of hormone secretionGO:0046887650.011
reactive oxygen species metabolic processGO:0072593370.011
activation of cysteine type endopeptidase activityGO:009720240.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
cellular response to corticosteroid stimulusGO:0071384690.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
cation homeostasisGO:00550801950.011
b cell differentiationGO:003018320.011
defense responseGO:00069521940.011
embryonic skeletal system developmentGO:004870630.011
regulation of organelle organizationGO:0033043800.011
anatomical structure morphogenesisGO:00096532980.011
respiratory system developmentGO:0060541450.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
regulation of protein maturationGO:1903317500.011
regulation of response to stressGO:00801341260.011
organic acid transportGO:00158491160.011
regulation of secretion by cellGO:19035302080.011
regulation of hormone secretionGO:00468831060.011
actin cytoskeleton organizationGO:0030036730.011
response to biotic stimulusGO:00096072260.011
positive regulation of neurogenesisGO:00507691650.011
acid secretionGO:0046717480.011
cellular protein complex assemblyGO:0043623440.011
muscle cell proliferationGO:0033002840.011
cyclic nucleotide biosynthetic processGO:0009190630.010
actin filament based processGO:0030029860.010
secretion by cellGO:00329402480.010
nucleoside triphosphate catabolic processGO:00091431230.010
regulation of proteolysisGO:0030162660.010
gonad developmentGO:00084061040.010
neuronal action potentialGO:0019228350.010
mitotic cell cycleGO:0000278490.010
nucleoside phosphate catabolic processGO:19012921400.010
cell projection morphogenesisGO:00488581230.010
positive regulation of mitochondrion organizationGO:001082240.010
negative regulation of nervous system developmentGO:0051961790.010
cardiovascular system developmentGO:00723581340.010
ribonucleotide catabolic processGO:00092611360.010
cellular protein localizationGO:00346131220.010
negative regulation of protein maturationGO:1903318470.010
regulation of proteasomal protein catabolic processGO:006113640.010
negative regulation of neurogenesisGO:0050768780.010
lipid biosynthetic processGO:00086101280.010
purine ribonucleoside triphosphate metabolic processGO:00092051400.010

Dhodh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.016
disease of anatomical entityDOID:700.016
musculoskeletal system diseaseDOID:1700.013
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
disease of metabolismDOID:001466700.011