Rattus norvegicus

13 known processes

Akap12

A kinase (PRKA) anchor protein 12

(Aliases: AKAP12A,AKAP12B,AKAP12G)

Akap12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular component movementGO:00512701500.259
localization of cellGO:00516742020.188
purine containing compound metabolic processGO:00725212530.181
cellular response to endogenous stimulusGO:00714953770.177
cell migrationGO:00164771970.171
regulation of cell migrationGO:00303341280.168
cellular catabolic processGO:00442482950.162
positive regulation of nitrogen compound metabolic processGO:00511733340.153
single organism catabolic processGO:00447122830.147
cellular response to organonitrogen compoundGO:00714171970.145
positive regulation of nucleobase containing compound metabolic processGO:00459353190.133
cell projection organizationGO:00300303020.132
cell motilityGO:00488702020.126
cellular component movementGO:00069282480.126
neuron projection developmentGO:00311752730.121
carbohydrate derivative metabolic processGO:19011353460.119
regulation of phosphate metabolic processGO:00192203490.118
organophosphate metabolic processGO:00196373700.117
regulation of molecular functionGO:00650093980.117
regulation of multicellular organismal developmentGO:20000263760.115
ribonucleoside catabolic processGO:00424541260.114
macromolecular complex subunit organizationGO:00439333390.110
anatomical structure morphogenesisGO:00096532980.109
regulation of cell motilityGO:20001451310.106
neuron differentiationGO:00301823680.106
organic substance catabolic processGO:19015753160.100
cellular component morphogenesisGO:00329891550.100
regulation of cell proliferationGO:00421273590.097
neuron developmentGO:00486662860.097
positive regulation of macromolecule biosynthetic processGO:00105572470.094
intracellular signal transductionGO:00355563140.094
response to inorganic substanceGO:00100353770.094
secretionGO:00469033070.093
purine nucleoside catabolic processGO:00061521240.090
regulation of cell differentiationGO:00455953200.089
purine ribonucleoside metabolic processGO:00461281680.086
regulation of cellular component organizationGO:00511283680.086
catabolic processGO:00090563510.085
positive regulation of cellular biosynthetic processGO:00313282950.084
organelle organizationGO:00069962660.083
cell morphogenesisGO:00009021420.083
tissue developmentGO:00098882520.082
circulatory system developmentGO:00723591340.080
positive regulation of cellular component movementGO:00512721020.079
response to peptideGO:19016522920.079
glycosyl compound metabolic processGO:19016571820.079
cell morphogenesis involved in neuron differentiationGO:00486671060.079
central nervous system developmentGO:00074173110.078
nucleobase containing small molecule metabolic processGO:00550863160.077
response to hypoxiaGO:00016662310.077
positive regulation of cell deathGO:00109421840.076
positive regulation of cell migrationGO:0030335960.075
regulation of phosphorus metabolic processGO:00511743490.074
regulation of cellular localizationGO:00603412630.074
positive regulation of developmental processGO:00510942830.073
positive regulation of phosphate metabolic processGO:00459372620.072
embryonic skeletal system developmentGO:004870630.070
positive regulation of phosphorus metabolic processGO:00105622620.070
regulation of programmed cell deathGO:00430673410.070
reproductive processGO:00224143720.069
single organism organelle organizationGO:19025891800.069
positive regulation of cell proliferationGO:00082842490.069
positive regulation of cell communicationGO:00106472710.068
regulation of phosphorylationGO:00423252480.068
cellular response to oxygen containing compoundGO:19017013860.067
ribonucleoside triphosphate metabolic processGO:00091991410.067
positive regulation of rna biosynthetic processGO:19026801970.067
protein complex subunit organizationGO:00718223020.067
multicellular organism reproductionGO:00325042330.067
cellular component biogenesisGO:00440853680.065
regulation of catalytic activityGO:00507903040.064
agingGO:00075682410.064
regulation of apoptotic processGO:00429813350.064
regulation of cell developmentGO:00602842630.063
nucleic acid templated transcriptionGO:00976593790.063
eye developmentGO:0001654500.062
cellular response to hormone stimulusGO:00328702470.062
regulation of nucleic acid templated transcriptionGO:19035063800.061
organic acid metabolic processGO:00060822920.061
nucleoside catabolic processGO:00091641260.061
locomotionGO:00400112370.061
organonitrogen compound catabolic processGO:19015651790.060
positive regulation of nervous system developmentGO:00519621780.060
cellular response to peptideGO:19016531330.060
response to nutrientGO:00075842480.060
purine nucleoside metabolic processGO:00422781690.060
cell morphogenesis involved in differentiationGO:00009041190.059
positive regulation of programmed cell deathGO:00430681570.059
positive regulation of multicellular organismal processGO:00512403870.058
response to extracellular stimulusGO:00099913800.058
reproductionGO:00000032450.058
growthGO:00400071650.058
positive regulation of biosynthetic processGO:00098913190.058
multicellular organismal reproductive processGO:00486092330.057
regulation of locomotionGO:00400121480.057
positive regulation of gene expressionGO:00106282440.056
purine ribonucleotide catabolic processGO:00091541360.056
ribose phosphate metabolic processGO:00196932350.056
brain developmentGO:00074202470.056
purine ribonucleoside catabolic processGO:00461301240.056
cellular response to nitrogen compoundGO:19016992100.056
nucleoside metabolic processGO:00091161790.056
muscle cell proliferationGO:0033002840.055
carbohydrate derivative catabolic processGO:19011361470.055
cardiovascular system developmentGO:00723581340.054
positive regulation of locomotionGO:00400171020.054
regulation of system processGO:00440572080.054
response to acid chemicalGO:00011012220.054
purine ribonucleoside triphosphate metabolic processGO:00092051400.053
wound healingGO:00420601220.053
oxoacid metabolic processGO:00434362900.053
nucleotide metabolic processGO:00091172790.053
cellular response to stressGO:00335542690.052
positive regulation of apoptotic processGO:00430651540.052
rna biosynthetic processGO:00327743800.052
apoptotic processGO:00069153810.050
anatomical structure formation involved in morphogenesisGO:0048646830.050
cellular response to growth factor stimulusGO:00713631620.050
cellular amino acid metabolic processGO:00065201070.050
positive regulation of transcription dna templatedGO:00458931970.050
cellular nitrogen compound catabolic processGO:00442701630.050
carboxylic acid metabolic processGO:00197522890.049
regulation of intracellular signal transductionGO:19025312180.049
multi multicellular organism processGO:00447061380.049
programmed cell deathGO:00125013920.049
guanosine containing compound metabolic processGO:1901068740.048
glycosyl compound catabolic processGO:19016581260.048
organophosphate catabolic processGO:00464341480.048
positive regulation of molecular functionGO:00440932300.048
positive regulation of ion transportGO:0043270940.047
blood vessel developmentGO:0001568690.047
regulation of neurogenesisGO:00507672470.047
cytoskeleton organizationGO:00070101110.046
small gtpase mediated signal transductionGO:0007264360.046
regulation of transcription dna templatedGO:00063553740.046
nucleoside phosphate metabolic processGO:00067532830.046
ribonucleotide metabolic processGO:00092592310.045
positive regulation of cell differentiationGO:00455972170.045
chemotaxisGO:0006935660.044
response to nutrient levelsGO:00316673700.044
axonogenesisGO:0007409710.044
positive regulation of phosphorylationGO:00423271770.044
ribonucleotide catabolic processGO:00092611360.044
cellular amine metabolic processGO:0044106380.044
positive regulation of catalytic activityGO:00430851840.043
regulation of mapk cascadeGO:00434081160.043
purine nucleotide catabolic processGO:00061951360.043
response to oxidative stressGO:00069791860.043
regulation of neuron apoptotic processGO:0043523830.043
response to amino acidGO:0043200750.043
purine containing compound catabolic processGO:00725231380.042
negative regulation of macromolecule metabolic processGO:00106052600.042
response to woundingGO:00096112540.042
regulation of rna metabolic processGO:00512523910.042
cellular component assemblyGO:00226073600.042
cell part morphogenesisGO:00329901230.042
positive regulation of rna metabolic processGO:00512542030.042
homeostatic processGO:00425923310.042
single organism intracellular transportGO:19025821660.042
response to radiationGO:00093141370.042
heterocycle catabolic processGO:00467001670.042
transcription dna templatedGO:00063513770.042
aromatic compound catabolic processGO:00194391680.042
organic cyclic compound catabolic processGO:19013611750.042
positive regulation of cellular component organizationGO:00511302000.041
immune system processGO:00023762040.041
guanosine containing compound catabolic processGO:1901069710.041
rna metabolic processGO:00160704060.041
response to decreased oxygen levelsGO:00362932370.041
cellular response to peptide hormone stimulusGO:00713751200.040
mapk cascadeGO:00001651400.040
signal transduction by phosphorylationGO:00230141440.040
purine nucleoside triphosphate metabolic processGO:00091441410.040
nucleoside phosphate catabolic processGO:19012921400.039
protein complex assemblyGO:00064612630.039
positive regulation of neurogenesisGO:00507691650.039
nucleotide catabolic processGO:00091661390.039
positive regulation of transportGO:00510502450.039
regulation of neuron differentiationGO:00456642080.038
regulation of cell projection organizationGO:00313441750.038
purine nucleotide metabolic processGO:00061632290.038
response to oxygen levelsGO:00704822650.038
macromolecular complex assemblyGO:00650032730.038
response to carbohydrateGO:00097431830.038
regulation of response to stressGO:00801341260.038
axon developmentGO:0061564960.037
positive regulation of signal transductionGO:00099671750.037
regulation of nervous system developmentGO:00519602640.037
cell cell signalingGO:00072673350.036
purine nucleoside triphosphate catabolic processGO:00091461220.036
cellular ketone metabolic processGO:0042180510.036
inflammatory responseGO:00069541500.035
single organism reproductive processGO:00447022970.035
regulation of secretionGO:00510462240.035
regulation of secretion by cellGO:19035302080.035
regulation of cell morphogenesisGO:0022604770.035
negative regulation of developmental processGO:00510931250.035
neuron projection morphogenesisGO:00488121220.035
positive regulation of signalingGO:00230562700.035
regulation of nucleotide metabolic processGO:00061401170.035
response to peptide hormoneGO:00434342780.035
actin filament based processGO:0030029860.034
head developmentGO:00603222470.034
response to metal ionGO:00100382530.034
negative regulation of signalingGO:00230571570.034
neuron apoptotic processGO:0051402880.034
regulation of neuron projection developmentGO:00109751610.034
nitrogen compound transportGO:00717052290.033
purine ribonucleoside triphosphate catabolic processGO:00092071220.033
response to estradiolGO:00323551640.033
sexual reproductionGO:00199531480.033
taxisGO:0042330670.033
sensory organ developmentGO:0007423740.033
salivary gland morphogenesisGO:000743510.033
gtp metabolic processGO:0046039720.033
negative regulation of cell communicationGO:00106481580.033
ras protein signal transductionGO:0007265290.033
response to growth factorGO:00708481890.033
regulation of signal transductionGO:00099663180.033
regulation of cell cycleGO:0051726730.033
response to estrogenGO:00436272320.032
signal releaseGO:00230611450.032
organ morphogenesisGO:0009887750.032
protein phosphorylationGO:00064683450.032
neuron deathGO:00709971270.032
response to alkaloidGO:00432791320.032
nucleobase containing compound catabolic processGO:00346551520.032
purine ribonucleotide metabolic processGO:00091502270.031
regulation of catabolic processGO:00098941130.031
regulation of cellular protein metabolic processGO:00322682670.031
positive regulation of response to stimulusGO:00485842850.031
nucleoside triphosphate catabolic processGO:00091431230.031
protein complex biogenesisGO:00702712630.031
transmembrane transportGO:00550854120.031
ion homeostasisGO:00508012120.031
positive regulation of mapk cascadeGO:0043410920.031
cell projection morphogenesisGO:00488581230.031
regulation of growthGO:00400081050.031
organonitrogen compound biosynthetic processGO:19015661670.031
chemical homeostasisGO:00488782920.030
positive regulation of intracellular signal transductionGO:19025331380.030
smooth muscle cell proliferationGO:0048659770.030
positive regulation of cell developmentGO:00107201760.030
cell growthGO:00160491040.030
regulation of hydrolase activityGO:00513361430.030
establishment of protein localizationGO:00451841410.030
positive regulation of nucleic acid templated transcriptionGO:19035081970.030
response to bacteriumGO:00096172000.030
biological adhesionGO:00226101100.030
multi organism reproductive processGO:00447032620.029
intracellular transportGO:00469071850.029
regulation of cellular amine metabolic processGO:003323880.029
regulation of canonical wnt signaling pathwayGO:006082840.029
regulation of purine nucleotide catabolic processGO:0033121650.029
negative regulation of metabolic processGO:00098923310.029
amine metabolic processGO:0009308380.029
organic acid transportGO:00158491160.029
negative regulation of multicellular organismal processGO:00512412030.028
embryonic skeletal system morphogenesisGO:004870430.028
neurological system processGO:00508772190.028
cellular response to organic cyclic compoundGO:00714072020.028
negative regulation of cellular metabolic processGO:00313242810.028
response to cytokineGO:00340972150.028
single organism biosynthetic processGO:00447113420.028
regulation of cellular ketone metabolic processGO:0010565270.028
heart morphogenesisGO:000300730.028
gtp catabolic processGO:0006184710.028
cellular response to reactive oxygen speciesGO:0034614550.028
hormone transportGO:00099141210.028
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.027
positive regulation of cell projection organizationGO:00313461110.027
nucleoside triphosphate metabolic processGO:00091411440.027
cellular lipid metabolic processGO:00442552080.027
inorganic ion transmembrane transportGO:00986602290.027
organic acid biosynthetic processGO:0016053830.026
regulation of rna biosynthetic processGO:20011413810.026
cation transportGO:00068123820.026
regulation of anatomical structure morphogenesisGO:00226031410.026
negative regulation of nucleobase containing compound metabolic processGO:00459341530.026
positive regulation of cell motilityGO:2000147970.026
negative regulation of programmed cell deathGO:00430691830.026
cellular response to transforming growth factor beta stimulusGO:0071560410.026
vasculature developmentGO:0001944700.026
cellular divalent inorganic cation homeostasisGO:00725031620.025
response to reactive oxygen speciesGO:00003021200.025
response to organophosphorusGO:00466831020.025
regulation of purine nucleotide metabolic processGO:19005421150.025
response to hexoseGO:00097461440.025
regulation of cellular catabolic processGO:00313291010.025
camera type eye developmentGO:0043010480.025
gland developmentGO:00487321550.025
negative regulation of phosphate metabolic processGO:0045936800.025
angiogenesisGO:0001525530.025
action potentialGO:0001508540.024
blood vessel morphogenesisGO:0048514580.024
positive regulation of jnk cascadeGO:0046330130.024
response to other organismGO:00517072200.024
cellular response to biotic stimulusGO:0071216590.024
g protein coupled receptor signaling pathwayGO:00071862420.024
tube developmentGO:0035295890.024
cellular ion homeostasisGO:00068731840.024
regulation of cellular amino acid metabolic processGO:000652120.024
lipid metabolic processGO:00066292830.024
small molecule biosynthetic processGO:00442831240.024
regulation of membrane potentialGO:00423911100.024
ribonucleoside triphosphate catabolic processGO:00092031220.024
blood circulationGO:00080151830.024
negative regulation of cell deathGO:00605482290.023
response to ketoneGO:19016541820.023
regulation of blood circulationGO:19035221100.023
metal ion homeostasisGO:00550651860.023
lipid biosynthetic processGO:00086101280.023
positive regulation of protein metabolic processGO:00512471780.023
negative regulation of response to stimulusGO:00485851550.023
regulation of smooth muscle cell proliferationGO:0048660750.023
digestive system developmentGO:0055123410.023
enzyme linked receptor protein signaling pathwayGO:00071671160.023
neuronal action potentialGO:0019228350.023
organic hydroxy compound metabolic processGO:19016151150.023
cellular protein localizationGO:00346131220.023
response to purine containing compoundGO:00140741260.023
negative regulation of apoptotic processGO:00430661810.023
ion transmembrane transportGO:00342203650.022
response to glucocorticoidGO:00513842230.022
metal ion transportGO:00300012890.022
response to ionizing radiationGO:0010212590.022
calcium ion homeostasisGO:00550741620.022
regulation of hormone secretionGO:00468831060.022
bmp signaling pathwayGO:003050940.022
anion transportGO:00068201780.022
ribonucleoside metabolic processGO:00091191740.022
protein oligomerizationGO:00512591910.022
cellular response to cytokine stimulusGO:00713451270.021
mesenchymal cell proliferationGO:001046340.021
response to monosaccharideGO:00342841590.021
proteolysisGO:00065081750.021
secretion by cellGO:00329402480.021
cation homeostasisGO:00550801950.021
cardiac chamber developmentGO:000320510.021
cellular homeostasisGO:00197252520.021
negative regulation of cellular biosynthetic processGO:00313271610.021
reactive oxygen species biosynthetic processGO:190340980.021
regulation of protein metabolic processGO:00512462890.021
response to toxic substanceGO:00096361330.021
cardiac ventricle developmentGO:000323110.021
cellular cation homeostasisGO:00300031800.021
regulation of cellular response to stressGO:0080135490.020
cellular response to acid chemicalGO:0071229750.020
response to hyperoxiaGO:0055093450.020
regulation of hormone levelsGO:00108171870.020
positive regulation of neuron differentiationGO:00456661260.020
regulation of cell adhesionGO:0030155520.020
reactive oxygen species metabolic processGO:0072593370.020
negative regulation of cell proliferationGO:00082851190.020
protein homooligomerizationGO:0051260910.020
cellular response to oxidative stressGO:0034599760.020
multicellular organism growthGO:003526410.020
response to molecule of bacterial originGO:00022371940.020
carboxylic acid biosynthetic processGO:0046394830.019
negative regulation of transportGO:00510511360.019
response to ethanolGO:00454711620.019
gastrulationGO:000736920.019
defense responseGO:00069521940.019
transmission of nerve impulseGO:0019226420.019
positive regulation of secretion by cellGO:19035321280.019
mast cell migrationGO:009753140.019
cellular metal ion homeostasisGO:00068751720.019
regulation of nucleoside metabolic processGO:0009118660.019
positive regulation of purine nucleotide metabolic processGO:1900544910.019
cellular calcium ion homeostasisGO:00068741600.019
epithelium developmentGO:0060429960.019
vesicle mediated transportGO:00161921810.019
response to insulinGO:00328681330.018
negative regulation of biosynthetic processGO:00098901680.018
ensheathment of neuronsGO:0007272400.018
cellular response to lipidGO:00713962010.018
anterior posterior pattern specificationGO:000995210.018
response to hydrogen peroxideGO:0042542890.018
cell cycleGO:00070491010.018
negative regulation of cell differentiationGO:0045596990.018
regulation of gtp catabolic processGO:0033124580.018
cytosolic calcium ion homeostasisGO:00514801400.018
gamete generationGO:00072761240.018
cell type specific apoptotic processGO:00972851340.018
reproductive system developmentGO:00614581280.018
developmental growthGO:00485891000.018
response to vitaminGO:00332731310.018
negative regulation of macromolecule biosynthetic processGO:00105581480.017
developmental process involved in reproductionGO:00030061590.017
regulation of protein phosphorylationGO:00019321830.017
forebrain developmentGO:0030900980.017
tissue regenerationGO:0042246360.017
dna metabolic processGO:0006259960.017
macromolecule localizationGO:00330362520.017
spindle organizationGO:000705120.017
multicellular organismal signalingGO:0035637440.017
regulation of anatomical structure sizeGO:00900661350.017
cellular chemical homeostasisGO:00550822470.017
peptidyl amino acid modificationGO:00181931260.017
hormone secretionGO:00468791150.017
negative regulation of gene expressionGO:00106291990.017
learning or memoryGO:0007611900.017
salivary gland developmentGO:000743130.017
cation transmembrane transportGO:00986552630.017
cell adhesionGO:00071551100.017
response to campGO:0051591910.017
regulation of cellular component biogenesisGO:0044087860.017
regulation of cell growthGO:0001558850.017
negative regulation of cell developmentGO:0010721820.017
response to biotic stimulusGO:00096072260.017
positive regulation of cellular protein metabolic processGO:00322701670.016
regulation of immune system processGO:00026821230.016
positive regulation of secretionGO:00510471400.016
response to glucoseGO:00097491360.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
negative regulation of protein metabolic processGO:00512481140.016
regulation of stress activated protein kinase signaling cascadeGO:0070302230.016
inorganic cation transmembrane transportGO:00986622020.016
transcription from rna polymerase ii promoterGO:00063662520.016
negative regulation of rna biosynthetic processGO:19026791180.016
negative regulation of molecular functionGO:00440921330.016
circulatory system processGO:00030131830.016
stress activated protein kinase signaling cascadeGO:0031098370.016
female pregnancyGO:00075651220.016
negative regulation of rna metabolic processGO:00512531230.016
regenerationGO:00310991630.016
protein transportGO:00150311320.016
response to ammonium ionGO:0060359710.016
kidney developmentGO:0001822670.016
mesoderm developmentGO:000749820.016
cellular macromolecule localizationGO:00707271220.016
amino acid transportGO:0006865700.016
muscle structure developmentGO:0061061870.016
positive regulation of cellular amine metabolic processGO:003324030.016
regulation of reactive oxygen species metabolic processGO:2000377260.016
neural crest cell developmentGO:001403220.016
axon ensheathmentGO:0008366400.015
synaptic transmissionGO:00072682350.015
rho protein signal transductionGO:0007266110.015
leukocyte cell cell adhesionGO:000715940.015
positive regulation of protein modification processGO:00314011420.015
single organism cell adhesionGO:0098602460.015
negative regulation of transcription dna templatedGO:00458921160.015
actin cytoskeleton organizationGO:0030036730.015
myelinationGO:0042552390.015
regulation of homeostatic processGO:00328441010.015
actin crosslink formationGO:005176430.015
synapse organizationGO:0050808460.015
regulation of jnk cascadeGO:0046328190.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
sensory perceptionGO:00076001010.015
response to activityGO:0014823730.015
amide transportGO:00428861050.015
positive regulation of neuron projection developmentGO:0010976990.015
intracellular protein transportGO:0006886790.015
peptide transportGO:0015833970.015
axis specificationGO:000979840.014
regulation of stem cell differentiationGO:200073620.014
germ cell migrationGO:000835410.014
peptide secretionGO:0002790860.014
establishment of organelle localizationGO:0051656370.014
embryonic pattern specificationGO:000988010.014
organelle localizationGO:0051640550.014
response to transition metal nanoparticleGO:19902671220.014
meiotic cell cycle processGO:190304630.014
negative regulation of cellular protein metabolic processGO:00322691060.014
stress activated mapk cascadeGO:0051403350.014
eye morphogenesisGO:004859240.014
regulation of metal ion transportGO:00109591180.014
negative regulation of neuron differentiationGO:0045665620.014
negative regulation of nucleic acid templated transcriptionGO:19035071170.014
cell cycle processGO:0022402570.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
immune responseGO:00069551040.014
reactive nitrogen species metabolic processGO:200105710.014
cytoplasmic transportGO:00164821150.014
motor neuron axon guidanceGO:000804510.014
nucleoside phosphate biosynthetic processGO:19012931020.014
response to temperature stimulusGO:0009266940.014
cognitionGO:0050890920.014
regulation of gtpase activityGO:0043087570.014
monovalent inorganic cation transportGO:00156721720.014
somatic stem cell divisionGO:004810320.014
response to lipopolysaccharideGO:00324961910.014
epithelial cell differentiationGO:0030855710.014
organophosphate biosynthetic processGO:00904071430.013
behaviorGO:00076102050.013
regulation of response to woundingGO:1903034690.013
oxidation reduction processGO:00551143040.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
positive regulation of stress activated protein kinase signaling cascadeGO:0070304170.013
carbohydrate derivative biosynthetic processGO:19011371240.013
carboxylic acid transportGO:00469421150.013
divalent inorganic cation homeostasisGO:00725071650.013
cellular carbohydrate metabolic processGO:0044262720.013
regulation of peptide transportGO:0090087870.013

Akap12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022