Rattus norvegicus

0 known processes

Foxo3

forkhead box O3

(Aliases: Fkhrl1,Foxo3a)

Foxo3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleic acid templated transcriptionGO:00976593790.420
Human
regulation of nucleic acid templated transcriptionGO:19035063800.406
Human
transcription dna templatedGO:00063513770.303
Human
regulation of rna metabolic processGO:00512523910.275
Human
rna biosynthetic processGO:00327743800.269
Human
regulation of rna biosynthetic processGO:20011413810.263
Human
cellular response to oxygen containing compoundGO:19017013860.218
agingGO:00075682410.213
response to other organismGO:00517072200.205
positive regulation of biosynthetic processGO:00098913190.192
Human
cellular response to acid chemicalGO:0071229750.184
response to retinoic acidGO:0032526630.166
cellular response to lipidGO:00713962010.163
transcription from rna polymerase ii promoterGO:00063662520.151
Human
regulation of transcription from rna polymerase ii promoterGO:00063572340.150
Human
metal ion homeostasisGO:00550651860.149
regulation of transcription dna templatedGO:00063553740.147
Human
carbohydrate derivative metabolic processGO:19011353460.146
organophosphate metabolic processGO:00196373700.145
cellular response to hormone stimulusGO:00328702470.139
ion transmembrane transportGO:00342203650.130
rna metabolic processGO:00160704060.127
Human
cation homeostasisGO:00550801950.126
cation transmembrane transportGO:00986552630.116
response to decreased oxygen levelsGO:00362932370.108
response to acid chemicalGO:00011012220.104
intracellular signal transductionGO:00355563140.102
positive regulation of nitrogen compound metabolic processGO:00511733340.101
Human
macromolecular complex subunit organizationGO:00439333390.098
positive regulation of cellular biosynthetic processGO:00313282950.095
Human
positive regulation of rna biosynthetic processGO:19026801970.091
Human
inorganic cation transmembrane transportGO:00986622020.090
regulation of apoptotic processGO:00429813350.089
Human
negative regulation of apoptotic processGO:00430661810.086
response to molecule of bacterial originGO:00022371940.086
response to cytokineGO:00340972150.084
regulation of programmed cell deathGO:00430673410.084
Human
rhythmic processGO:00485111560.083
cellular response to organic cyclic compoundGO:00714072020.083
response to hypoxiaGO:00016662310.082
organic acid transportGO:00158491160.080
organophosphate biosynthetic processGO:00904071430.079
ribonucleotide metabolic processGO:00092592310.075
multicellular organism reproductionGO:00325042330.073
negative regulation of nitrogen compound metabolic processGO:00511721610.072
Human
positive regulation of rna metabolic processGO:00512542030.072
Human
response to bacteriumGO:00096172000.071
cyclic nucleotide metabolic processGO:0009187800.070
brain developmentGO:00074202470.070
carbohydrate derivative biosynthetic processGO:19011371240.070
cell migrationGO:00164771970.069
positive regulation of nucleic acid templated transcriptionGO:19035081970.068
Human
negative regulation of macromolecule biosynthetic processGO:00105581480.065
Human
cellular response to stressGO:00335542690.064
response to purine containing compoundGO:00140741260.063
negative regulation of macromolecule metabolic processGO:00106052600.063
Human
multi multicellular organism processGO:00447061380.063
action potentialGO:0001508540.062
inorganic ion transmembrane transportGO:00986602290.061
carboxylic acid transportGO:00469421150.060
single organism reproductive processGO:00447022970.060
nucleoside phosphate metabolic processGO:00067532830.060
cellular cation homeostasisGO:00300031800.058
response to extracellular stimulusGO:00099913800.058
cation transportGO:00068123820.058
chemical homeostasisGO:00488782920.057
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.056
Human
cellular response to endogenous stimulusGO:00714953770.056
organonitrogen compound biosynthetic processGO:19015661670.055
positive regulation of nucleobase containing compound metabolic processGO:00459353190.055
Human
circadian rhythmGO:0007623880.055
negative regulation of rna metabolic processGO:00512531230.054
Human
cardiovascular system developmentGO:00723581340.053
regulation of ion transportGO:00432692450.051
regulation of phosphorus metabolic processGO:00511743490.051
negative regulation of cell proliferationGO:00082851190.050
cellular chemical homeostasisGO:00550822470.050
reproductive processGO:00224143720.050
neurological system processGO:00508772190.049
response to external biotic stimulusGO:00432072210.049
purine nucleotide metabolic processGO:00061632290.049
single organism biosynthetic processGO:00447113420.049
response to peptide hormoneGO:00434342780.048
multi organism reproductive processGO:00447032620.048
calcium ion importGO:0070509220.046
smooth muscle cell proliferationGO:0048659770.046
regulation of smooth muscle cell proliferationGO:0048660750.045
response to oxygen levelsGO:00704822650.045
nucleobase containing small molecule metabolic processGO:00550863160.045
amino acid transportGO:0006865700.045
cellular metal ion homeostasisGO:00068751720.045
cellular response to retinoic acidGO:0071300270.045
positive regulation of developmental processGO:00510942830.044
Human
programmed cell deathGO:00125013920.044
Human
regulation of intracellular signal transductionGO:19025312180.044
regulation of multicellular organismal developmentGO:20000263760.044
Human
neuron deathGO:00709971270.044
Human
response to light stimulusGO:0009416520.043
regulation of cell proliferationGO:00421273590.043
response to estradiolGO:00323551640.043
cellular ion homeostasisGO:00068731840.042
circulatory system developmentGO:00723591340.042
cell growthGO:00160491040.042
apoptotic processGO:00069153810.041
Human
muscle cell proliferationGO:0033002840.040
positive regulation of phosphate metabolic processGO:00459372620.039
ribose phosphate biosynthetic processGO:0046390870.039
positive regulation of transcription dna templatedGO:00458931970.039
Human
ion homeostasisGO:00508012120.039
positive regulation of catalytic activityGO:00430851840.039
cyclic nucleotide biosynthetic processGO:0009190630.039
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.038
Human
response to nutrient levelsGO:00316673700.038
homeostatic processGO:00425923310.038
Human
negative regulation of biosynthetic processGO:00098901680.038
Human
cellular calcium ion homeostasisGO:00068741600.037
mapk cascadeGO:00001651400.037
negative regulation of multicellular organismal processGO:00512412030.037
negative regulation of cell deathGO:00605482290.036
catabolic processGO:00090563510.036
positive regulation of phosphorus metabolic processGO:00105622620.036
locomotionGO:00400112370.036
cellular homeostasisGO:00197252520.035
regulation of phosphate metabolic processGO:00192203490.035
female mating behaviorGO:006018060.035
regulation of signal transductionGO:00099663180.034
response to alkaloidGO:00432791320.034
positive regulation of gene expressionGO:00106282440.034
Human
response to radiationGO:00093141370.034
secretionGO:00469033070.034
organ regenerationGO:00311001010.034
protein phosphorylationGO:00064683450.034
multicellular organismal signalingGO:0035637440.033
regulation of cellular ketone metabolic processGO:0010565270.032
regulation of growthGO:00400081050.032
negative regulation of nucleobase containing compound metabolic processGO:00459341530.032
Human
response to temperature stimulusGO:0009266940.032
cellular divalent inorganic cation homeostasisGO:00725031620.032
central nervous system developmentGO:00074173110.032
ribonucleotide biosynthetic processGO:0009260850.032
negative regulation of gene expressionGO:00106291990.032
Human
blood circulationGO:00080151830.032
cellular ketone metabolic processGO:0042180510.031
response to foodGO:0032094270.031
purine containing compound metabolic processGO:00725212530.031
organic anion transportGO:00157111320.030
heart developmentGO:0007507720.030
monocarboxylic acid metabolic processGO:00327871520.030
response to organophosphorusGO:00466831020.030
regulation of catalytic activityGO:00507903040.030
protein complex assemblyGO:00064612630.029
regulation of blood pressureGO:0008217830.029
regulation of cell growthGO:0001558850.029
response to toxic substanceGO:00096361330.029
cell motilityGO:00488702020.029
nucleoside phosphate biosynthetic processGO:19012931020.028
calcium ion homeostasisGO:00550741620.028
regulation of lipid metabolic processGO:0019216680.028
localization of cellGO:00516742020.028
response to nutrientGO:00075842480.028
neuron developmentGO:00486662860.028
interleukin 18 productionGO:003262110.028
response to glucocorticoidGO:00513842230.027
cellular response to organonitrogen compoundGO:00714171970.027
response to lipopolysaccharideGO:00324961910.027
regulation of cellular protein metabolic processGO:00322682670.027
Human
negative regulation of phosphate metabolic processGO:0045936800.027
response to carbohydrateGO:00097431830.027
regulation of nervous system developmentGO:00519602640.027
divalent inorganic cation homeostasisGO:00725071650.027
transmission of nerve impulseGO:0019226420.026
negative regulation of metabolic processGO:00098923310.026
Human
nitrogen compound transportGO:00717052290.026
g protein coupled receptor signaling pathwayGO:00071862420.026
cytosolic calcium ion homeostasisGO:00514801400.026
negative regulation of cellular biosynthetic processGO:00313271610.026
Human
protein oligomerizationGO:00512591910.026
regulation of cell motilityGO:20001451310.026
anion transportGO:00068201780.025
positive regulation of intracellular signal transductionGO:19025331380.025
nucleotide biosynthetic processGO:0009165980.025
macromolecular complex assemblyGO:00650032730.025
response to hexoseGO:00097461440.025
response to metal ionGO:00100382530.024
regulation of purine nucleotide metabolic processGO:19005421150.024
organ formationGO:004864530.024
cellular response to growth factor stimulusGO:00713631620.024
positive regulation of smooth muscle cell proliferationGO:0048661510.024
cellular response to glucocorticoid stimulusGO:0071385680.024
regulation of cellular localizationGO:00603412630.024
organic hydroxy compound metabolic processGO:19016151150.024
ribose phosphate metabolic processGO:00196932350.024
response to fungicideGO:0060992200.023
heart morphogenesisGO:000300730.023
regulation of cell migrationGO:00303341280.023
tolerance induction dependent upon immune responseGO:000246120.023
cellular carbohydrate metabolic processGO:0044262720.023
positive regulation of interleukin 18 productionGO:003274110.023
cellular response to extracellular stimulusGO:0031668730.023
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.023
Human
protein complex biogenesisGO:00702712630.023
developmental process involved in reproductionGO:00030061590.023
response to reactive oxygen speciesGO:00003021200.022
regulation of cyclic nucleotide metabolic processGO:0030799510.022
purine ribonucleotide biosynthetic processGO:0009152810.022
regulation of cellular carbohydrate metabolic processGO:0010675390.022
positive regulation of cell proliferationGO:00082842490.022
response to inorganic substanceGO:00100353770.022
reproductionGO:00000032450.022
regulation of cellular component organizationGO:00511283680.022
regulation of metal ion transportGO:00109591180.022
regulation of blood vessel sizeGO:0050880890.021
negative regulation of transportGO:00510511360.021
female pregnancyGO:00075651220.021
response to glucoseGO:00097491360.021
response to growth factorGO:00708481890.021
regulation of system processGO:00440572080.021
sensory organ developmentGO:0007423740.021
regulation of membrane potentialGO:00423911100.021
response to corticosteroidGO:00319602350.021
regulation of molecular functionGO:00650093980.020
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.020
signal transduction by phosphorylationGO:00230141440.020
regulation of carbohydrate metabolic processGO:0006109410.020
substrate dependent cell migrationGO:000692910.020
multicellular organismal reproductive processGO:00486092330.020
regulation of cellular component movementGO:00512701500.020
metal ion transportGO:00300012890.020
response to estrogenGO:00436272320.020
salivary gland developmentGO:000743130.020
negative regulation of cell communicationGO:00106481580.020
cellular response to cytokine stimulusGO:00713451270.020
head developmentGO:00603222470.020
eye morphogenesisGO:004859240.019
response to campGO:0051591910.019
nucleotide metabolic processGO:00091172790.019
growthGO:00400071650.019
regulation of secretionGO:00510462240.019
negative regulation of developmental processGO:00510931250.019
sex differentiationGO:00075481130.019
negative regulation of cellular metabolic processGO:00313242810.019
Human
axis specificationGO:000979840.019
phenol containing compound metabolic processGO:0018958300.019
cellular response to steroid hormone stimulusGO:0071383930.018
cell type specific apoptotic processGO:00972851340.018
Human
single organism intracellular transportGO:19025821660.018
response to hydrogen peroxideGO:0042542890.018
negative regulation of cell developmentGO:0010721820.018
proteolysisGO:00065081750.018
purine containing compound biosynthetic processGO:0072522850.018
enzyme linked receptor protein signaling pathwayGO:00071671160.018
modified amino acid transportGO:0072337120.017
negative regulation of transcription dna templatedGO:00458921160.017
Human
purine ribonucleotide metabolic processGO:00091502270.017
positive regulation of cytosolic calcium ion concentrationGO:00072041220.017
regulation of protein metabolic processGO:00512462890.017
Human
vascular process in circulatory systemGO:0003018960.017
protein complex subunit organizationGO:00718223020.017
regenerationGO:00310991630.017
positive regulation of hydrolase activityGO:0051345860.017
multicellular organism growthGO:003526410.017
myeloid cell differentiationGO:0030099220.017
Human
response to oxidative stressGO:00069791860.017
regulation of locomotionGO:00400121480.017
response to biotic stimulusGO:00096072260.016
regulation of neurogenesisGO:00507672470.016
divalent inorganic cation transportGO:00725111340.016
positive regulation of secretion by cellGO:19035321280.016
response to monosaccharideGO:00342841590.016
negative regulation of pancreatic stellate cell proliferationGO:200023010.016
positive regulation of programmed cell deathGO:00430681570.016
Human
response to peptideGO:19016522920.016
regulation of mapk cascadeGO:00434081160.016
steroid metabolic processGO:0008202730.016
tissue developmentGO:00098882520.016
regulation of nucleotide biosynthetic processGO:0030808470.016
response to ionizing radiationGO:0010212590.016
organelle organizationGO:00069962660.016
positive regulation of molecular functionGO:00440932300.016
positive regulation of signal transductionGO:00099671750.016
neuronal action potentialGO:0019228350.016
cytoskeleton organizationGO:00070101110.016
regulation of tube sizeGO:0035150890.016
cellular response to corticosteroid stimulusGO:0071384690.015
t cell tolerance inductionGO:000251730.015
lipid biosynthetic processGO:00086101280.015
vesicle mediated transportGO:00161921810.015
response to transition metal nanoparticleGO:19902671220.015
cellular component assemblyGO:00226073600.015
reproductive system developmentGO:00614581280.015
regulation of cellular amine metabolic processGO:003323880.015
multicellular organismal response to stressGO:0033555250.015
cellular response to nitrogen compoundGO:19016992100.014
cellular catabolic processGO:00442482950.014
cellular response to molecule of bacterial originGO:0071219560.014
negative regulation of rna biosynthetic processGO:19026791180.014
Human
organic hydroxy compound transportGO:0015850770.014
learning or memoryGO:0007611900.014
regulation of hormone levelsGO:00108171870.014
calcium ion transportGO:00068161310.014
camera type eye morphogenesisGO:004859320.014
cerebral cortex cell migrationGO:002179540.014
response to activityGO:0014823730.014
cellular potassium ion transportGO:0071804720.014
amine metabolic processGO:0009308380.014
protein homooligomerizationGO:0051260910.014
embryonic appendage morphogenesisGO:003511340.014
cerebral cortex tangential migrationGO:002180010.014
organic hydroxy compound biosynthetic processGO:1901617510.014
negative regulation of programmed cell deathGO:00430691830.014
forebrain developmentGO:0030900980.014
cellular component movementGO:00069282480.014
hexose metabolic processGO:0019318580.014
regulation of protein kinase activityGO:00458591050.014
cellular amine metabolic processGO:0044106380.013
regulation of epithelial cell proliferationGO:0050678490.013
positive regulation of growthGO:0045927550.013
response to insulinGO:00328681330.013
positive regulation of cellular component organizationGO:00511302000.013
positive regulation of macromolecule biosynthetic processGO:00105572470.013
Human
regulation of cell projection organizationGO:00313441750.013
appendage morphogenesisGO:003510740.013
gliogenesisGO:0042063930.013
regulation of cell morphogenesis involved in differentiationGO:0010769720.013
palate developmentGO:006002120.013
response to starvationGO:0042594590.013
glutamate receptor signaling pathwayGO:0007215430.013
regulation of cell developmentGO:00602842630.013
negative regulation of signalingGO:00230571570.013
camp metabolic processGO:0046058630.013
secretion by cellGO:00329402480.013
oxoacid metabolic processGO:00434362900.013
regulation of secretion by cellGO:19035302080.013
negative regulation of cell differentiationGO:0045596990.012
glucose metabolic processGO:0006006520.012
acid secretionGO:0046717480.012
synaptic transmissionGO:00072682350.012
bmp signaling pathwayGO:003050940.012
norepinephrine transportGO:0015874180.012
positive regulation of cellular protein metabolic processGO:00322701670.012
positive regulation of purine nucleotide biosynthetic processGO:1900373360.012
response to ammonium ionGO:0060359710.012
catecholamine transportGO:0051937370.012
cellular response to abiotic stimulusGO:0071214850.012
anatomical structure morphogenesisGO:00096532980.012
jak stat cascadeGO:0007259260.012
vasculature developmentGO:0001944700.012
norepinephrine secretionGO:0048243160.012
neuron projection developmentGO:00311752730.012
negative regulation of phosphorus metabolic processGO:0010563800.012
inflammatory responseGO:00069541500.012
ras protein signal transductionGO:0007265290.012
development of primary sexual characteristicsGO:00451371070.012
fibroblast proliferationGO:0048144220.012
transmembrane transportGO:00550854120.012
positive regulation of developmental growthGO:0048639290.012
organic substance catabolic processGO:19015753160.012
response to calcium ionGO:0051592590.011
regulation of nucleotide metabolic processGO:00061401170.011
circulatory system processGO:00030131830.011
eye developmentGO:0001654500.011
regulation of anatomical structure sizeGO:00900661350.011
sexual reproductionGO:00199531480.011
positive regulation of secretionGO:00510471400.011
mrna transcriptionGO:000929920.011
keratinocyte migrationGO:005154620.011
potassium ion transmembrane transportGO:0071805710.011
renal sodium excretionGO:0035812200.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.011
regulation of blood circulationGO:19035221100.011
positive regulation of phosphorylationGO:00423271770.011
tube developmentGO:0035295890.011
positive regulation of cell deathGO:00109421840.011
Human
organic cyclic compound catabolic processGO:19013611750.011
positive regulation of cell differentiationGO:00455972170.011
Human
transformation of host cell by virusGO:001908740.011
positive regulation of multicellular organismal processGO:00512403870.011
Human
hormone biosynthetic processGO:0042446250.011
positive regulation of cellular amine metabolic processGO:003324030.011
embryonic pattern specificationGO:000988010.011
negative regulation of lyase activityGO:005135080.011
regulation of insulin secretionGO:0050796650.011
immune responseGO:00069551040.011
carbohydrate homeostasisGO:0033500750.011
response to metforminGO:190155810.010
sensory perceptionGO:00076001010.010
neuron differentiationGO:00301823680.010
carbohydrate biosynthetic processGO:0016051420.010
response to nicotineGO:0035094510.010
detection of visible lightGO:000958430.010
urogenital system developmentGO:0001655780.010
digestive tract developmentGO:0048565390.010
somatostatin receptor signaling pathwayGO:003816940.010
positive regulation of cellular amino acid metabolic processGO:004576410.010
positive regulation of apoptotic processGO:00430651540.010
Human
cellular component biogenesisGO:00440853680.010
neuromuscular processGO:005090520.010
myeloid leukocyte differentiationGO:0002573200.010
regulation of pancreatic stellate cell proliferationGO:200022920.010
positive regulation of transportGO:00510502450.010
response to mechanical stimulusGO:00096121340.010
response to atpGO:0033198130.010
negative regulation of neurogenesisGO:0050768780.010

Foxo3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.024
disease of anatomical entityDOID:700.024
connective tissue diseaseDOID:6500.018
bone diseaseDOID:008000100.018
musculoskeletal system diseaseDOID:1700.018
sensory system diseaseDOID:005015500.010