Rattus norvegicus

125 known processes

Pfkfb2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

(Aliases: RH2K)

Pfkfb2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle system processGO:00030121150.749
cytosolic calcium ion homeostasisGO:00514801400.728
calcium ion homeostasisGO:00550741620.717
regulation of ion transportGO:00432692450.590
heart processGO:0003015570.589
g protein coupled receptor signaling pathwayGO:00071862420.520
cellular metal ion homeostasisGO:00068751720.478
regulation of rna metabolic processGO:00512523910.458
regulation of phosphorus metabolic processGO:00511743490.453
divalent inorganic cation homeostasisGO:00725071650.440
cellular calcium ion homeostasisGO:00068741600.423
vesicle mediated transportGO:00161921810.419
transmembrane transportGO:00550854120.418
heart contractionGO:0060047570.404
positive regulation of transportGO:00510502450.398
metal ion transportGO:00300012890.388
homeostatic processGO:00425923310.387
divalent metal ion transportGO:00708381320.382
calcium ion importGO:0070509220.374
metal ion homeostasisGO:00550651860.359
secretion by cellGO:00329402480.341
cellular cation homeostasisGO:00300031800.338
positive regulation of signal transductionGO:00099671750.335
regulation of calcium ion transportGO:0051924770.315
cation transmembrane transportGO:00986552630.314
regulation of metal ion transportGO:00109591180.313
cognitionGO:0050890920.311
regulation of secretionGO:00510462240.310
mapk cascadeGO:00001651400.302
cellular divalent inorganic cation homeostasisGO:00725031620.301
positive regulation of nucleobase containing compound metabolic processGO:00459353190.301
learning or memoryGO:0007611900.289
positive regulation of secretion by cellGO:19035321280.288
actin filament based processGO:0030029860.277
positive regulation of cell communicationGO:00106472710.267
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.266
intracellular signal transductionGO:00355563140.260
divalent inorganic cation transportGO:00725111340.259
multicellular organism reproductionGO:00325042330.252
cellular chemical homeostasisGO:00550822470.252
enzyme linked receptor protein signaling pathwayGO:00071671160.252
negative regulation of cellular biosynthetic processGO:00313271610.242
blood circulationGO:00080151830.233
regulation of system processGO:00440572080.230
secretionGO:00469033070.230
cation transportGO:00068123820.219
hormone mediated signaling pathwayGO:0009755230.219
negative regulation of rna metabolic processGO:00512531230.217
carbohydrate derivative metabolic processGO:19011353460.216
cation homeostasisGO:00550801950.214
cellular response to oxygen containing compoundGO:19017013860.202
cell cell signalingGO:00072673350.201
negative regulation of biosynthetic processGO:00098901680.200
ion transmembrane transportGO:00342203650.196
regulation of transcription dna templatedGO:00063553740.194
cellular ion homeostasisGO:00068731840.194
single organism behaviorGO:00447081300.193
regulation of nucleic acid templated transcriptionGO:19035063800.177
regulation of mapk cascadeGO:00434081160.175
regulation of rna biosynthetic processGO:20011413810.173
signal transduction by phosphorylationGO:00230141440.173
cyclic nucleotide biosynthetic processGO:0009190630.172
neuron developmentGO:00486662860.172
neuron projection morphogenesisGO:00488121220.170
phototransduction visible lightGO:000760320.169
positive regulation of cytosolic calcium ion concentrationGO:00072041220.167
single organism biosynthetic processGO:00447113420.166
rna biosynthetic processGO:00327743800.165
regulation of cyclic nucleotide metabolic processGO:0030799510.164
calcium ion transportGO:00068161310.163
regulation of muscle contractionGO:0006937530.163
cellular homeostasisGO:00197252520.162
neurological system processGO:00508772190.161
regulation of blood vessel sizeGO:0050880890.154
positive regulation of transcription dna templatedGO:00458931970.153
protein localizationGO:00081041910.149
signal releaseGO:00230611450.148
single organism intracellular transportGO:19025821660.147
protein transportGO:00150311320.146
regulation of signal transductionGO:00099663180.146
rna metabolic processGO:00160704060.146
transcription from rna polymerase ii promoterGO:00063662520.145
head developmentGO:00603222470.145
Rat
response to hypoxiaGO:00016662310.143
cellular component assemblyGO:00226073600.142
cellular carbohydrate metabolic processGO:0044262720.141
organelle organizationGO:00069962660.140
cellular response to stressGO:00335542690.140
cell part morphogenesisGO:00329901230.139
memoryGO:0007613540.138
cell morphogenesisGO:00009021420.137
endocytosisGO:0006897840.136
regulation of muscle system processGO:0090257790.136
cellular component biogenesisGO:00440853680.136
circulatory system processGO:00030131830.134
regulation of heart contractionGO:0008016480.134
morphogenesis of an epitheliumGO:0002009200.134
ion homeostasisGO:00508012120.134
regulation of intracellular signal transductionGO:19025312180.133
nucleic acid templated transcriptionGO:00976593790.132
vascular process in circulatory systemGO:0003018960.131
neuron projection developmentGO:00311752730.130
multicellular organismal reproductive processGO:00486092330.130
regulation of vesicle mediated transportGO:0060627810.128
regulation of phosphorylationGO:00423252480.127
protein complex assemblyGO:00064612630.127
transcription dna templatedGO:00063513770.127
glutamate receptor signaling pathwayGO:0007215430.126
positive regulation of intracellular signal transductionGO:19025331380.125
regulation of exocytosisGO:0017157370.125
regulation of blood circulationGO:19035221100.125
macromolecule localizationGO:00330362520.124
detection of visible lightGO:000958430.123
positive regulation of biosynthetic processGO:00098913190.121
negative regulation of metabolic processGO:00098923310.118
regulation of behaviorGO:0050795610.118
neuron differentiationGO:00301823680.117
rhythmic processGO:00485111560.115
cellular response to nitrogen compoundGO:19016992100.115
cardiac muscle contractionGO:0060048270.115
regulation of molecular functionGO:00650093980.113
brain developmentGO:00074202470.111
Rat
cellular component movementGO:00069282480.111
response to radiationGO:00093141370.110
macromolecular complex subunit organizationGO:00439333390.110
chemical homeostasisGO:00488782920.110
negative regulation of apoptotic processGO:00430661810.109
renal sodium excretionGO:0035812200.107
response to oxygen levelsGO:00704822650.105
negative regulation of nitrogen compound metabolic processGO:00511721610.105
cellular response to lipidGO:00713962010.105
regulation of transcription from rna polymerase ii promoterGO:00063572340.104
central nervous system developmentGO:00074173110.104
Rat
striated muscle contractionGO:0006941440.103
organophosphate biosynthetic processGO:00904071430.102
positive regulation of mapk cascadeGO:0043410920.102
regulation of cellular component organizationGO:00511283680.102
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.099
negative regulation of macromolecule metabolic processGO:00106052600.099
regulation of transmembrane transporter activityGO:0022898490.099
cellular component morphogenesisGO:00329891550.098
response to light stimulusGO:0009416520.098
positive regulation of blood circulationGO:1903524650.097
regulation of ion transmembrane transporter activityGO:0032412480.097
positive regulation of synaptic transmissionGO:0050806620.096
cell type specific apoptotic processGO:00972851340.095
regulation of transferase activityGO:00513381230.094
prepulse inhibitionGO:006013410.094
regulation of protein modification processGO:00313991940.094
regulation of catecholamine secretionGO:0050433320.094
response to decreased oxygen levelsGO:00362932370.092
regulation of anatomical structure sizeGO:00900661350.090
regulation of multicellular organismal developmentGO:20000263760.089
regulation of neuron apoptotic processGO:0043523830.089
anterior posterior pattern specificationGO:000995210.089
positive regulation of signalingGO:00230562700.088
hormone transportGO:00099141210.088
purine containing compound metabolic processGO:00725212530.088
positive regulation of purine nucleotide metabolic processGO:1900544910.087
cell projection morphogenesisGO:00488581230.087
regulation of organelle organizationGO:0033043800.087
neurotrophin productionGO:003289820.086
stress activated protein kinase signaling cascadeGO:0031098370.086
hormone secretionGO:00468791150.086
cell projection organizationGO:00300303020.086
positive regulation of multicellular organismal processGO:00512403870.084
establishment of protein localizationGO:00451841410.083
negative regulation of macromolecule biosynthetic processGO:00105581480.083
regulation of cell proliferationGO:00421273590.081
sexual reproductionGO:00199531480.081
macromolecular complex assemblyGO:00650032730.080
ribose phosphate metabolic processGO:00196932350.080
cellular response to hormone stimulusGO:00328702470.078
reproductionGO:00000032450.078
purine nucleotide metabolic processGO:00061632290.077
cell cycleGO:00070491010.076
locomotory behaviorGO:0007626150.076
regulation of endocytosisGO:0030100420.074
response to inorganic substanceGO:00100353770.074
negative regulation of cell deathGO:00605482290.074
positive regulation of nitrogen compound metabolic processGO:00511733340.073
intracellular transportGO:00469071850.072
nucleotide metabolic processGO:00091172790.072
response to monosaccharideGO:00342841590.072
regulation of lipid biosynthetic processGO:0046890380.071
regulation of ion transmembrane transportGO:00347651210.071
negative regulation of response to stimulusGO:00485851550.070
agingGO:00075682410.070
reproductive processGO:00224143720.070
sensory perceptionGO:00076001010.069
positive regulation of ion transportGO:0043270940.069
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.069
synaptic transmissionGO:00072682350.069
protein complex subunit organizationGO:00718223020.068
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.068
negative regulation of signalingGO:00230571570.068
regulation of cellular localizationGO:00603412630.067
positive regulation of molecular functionGO:00440932300.067
membrane organizationGO:0061024940.067
locomotory exploration behaviorGO:003564110.066
positive regulation of peptide secretionGO:0002793520.066
regulation of protein transportGO:0051223680.066
intracellular protein transportGO:0006886790.066
tissue developmentGO:00098882520.065
protein phosphorylationGO:00064683450.065
positive regulation of nervous system developmentGO:00519621780.065
nitrogen compound transportGO:00717052290.065
negative regulation of signal transductionGO:0009968830.065
locomotionGO:00400112370.064
regulation of apoptotic processGO:00429813350.063
positive regulation of cell migrationGO:0030335960.063
purine nucleotide biosynthetic processGO:0006164830.063
positive regulation of rna biosynthetic processGO:19026801970.062
regulation of tube sizeGO:0035150890.062
negative regulation of programmed cell deathGO:00430691830.062
circadian rhythmGO:0007623880.061
regulation of cellular component biogenesisGO:0044087860.060
regulation of cellular protein metabolic processGO:00322682670.060
purine ribonucleotide metabolic processGO:00091502270.060
respiratory system processGO:000301630.060
anion transportGO:00068201780.059
anatomical structure morphogenesisGO:00096532980.059
protein complex biogenesisGO:00702712630.059
inorganic ion transmembrane transportGO:00986602290.059
positive regulation of phosphate metabolic processGO:00459372620.058
negative regulation of nucleobase containing compound metabolic processGO:00459341530.058
negative regulation of circadian sleep wake cycle sleepGO:004232150.058
negative regulation of nucleic acid templated transcriptionGO:19035071170.058
synaptic transmission gabaergicGO:0051932220.057
positive regulation of peptide hormone secretionGO:0090277500.057
regulation of neuron deathGO:19012141150.057
positive regulation of macromolecule biosynthetic processGO:00105572470.057
muscle contractionGO:0006936880.057
positive regulation of gene expressionGO:00106282440.057
negative regulation of vascular permeabilityGO:004311630.056
positive regulation of locomotionGO:00400171020.056
negative regulation of multicellular organismal processGO:00512412030.056
organonitrogen compound biosynthetic processGO:19015661670.056
sensory organ developmentGO:0007423740.055
pancreatic a cell differentiationGO:000331010.055
sequestering of metal ionGO:005123890.055
single organism cellular localizationGO:19025801020.054
positive regulation of cell developmentGO:00107201760.054
growthGO:00400071650.054
cellular response to external stimulusGO:00714961180.054
circulatory system developmentGO:00723591340.054
monoamine transportGO:0015844430.054
sequestering of calcium ionGO:005120880.053
negative regulation of gene expressionGO:00106291990.053
negative regulation of homeostatic processGO:0032845470.053
regulation of respiratory system processGO:004406510.053
cytoskeleton organizationGO:00070101110.053
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.053
positive regulation of cellular biosynthetic processGO:00313282950.052
negative regulation of rna biosynthetic processGO:19026791180.052
regulation of cardiac muscle contractionGO:0055117170.052
positive regulation of phosphorus metabolic processGO:00105622620.052
positive regulation of protein serine threonine kinase activityGO:0071902520.052
camp metabolic processGO:0046058630.051
multi organism reproductive processGO:00447032620.051
cellular macromolecule localizationGO:00707271220.051
regulation of cellular ketone metabolic processGO:0010565270.051
amide transportGO:00428861050.051
synaptic transmission glutamatergicGO:0035249330.051
response to mineralocorticoidGO:0051385490.050
programmed cell deathGO:00125013920.050
regulation of actin filament based movementGO:1903115120.050
ribonucleotide metabolic processGO:00092592310.050
receptor metabolic processGO:0043112180.050
epithelial cell differentiationGO:0030855710.049
synaptic growth at neuromuscular junctionGO:005112410.049
potassium ion transportGO:0006813970.048
nucleoside phosphate biosynthetic processGO:19012931020.048
actin mediated cell contractionGO:0070252120.048
response to extracellular stimulusGO:00099913800.048
Rat
nucleoside phosphate metabolic processGO:00067532830.048
second messenger mediated signalingGO:0019932510.048
response to starvationGO:0042594590.048
Rat
regulation of hormone secretionGO:00468831060.048
positive regulation of nucleic acid templated transcriptionGO:19035081970.048
regulation of cell developmentGO:00602842630.047
maintenance of locationGO:0051235170.047
positive regulation of cell deathGO:00109421840.047
leukocyte activation involved in immune responseGO:0002366160.047
protein heterooligomerizationGO:0051291890.047
myeloid leukocyte differentiationGO:0002573200.047
membrane repolarizationGO:008600910.046
cellular response to organic cyclic compoundGO:00714072020.046
response to fatty acidGO:0070542650.046
regulation of cell differentiationGO:00455953200.046
regulation of cellular component movementGO:00512701500.046
positive regulation of developmental processGO:00510942830.045
regulation of respiratory gaseous exchange by neurological system processGO:000208710.045
single organism reproductive processGO:00447022970.045
single organism organelle organizationGO:19025891800.045
negative regulation of cellular metabolic processGO:00313242810.045
positive regulation of secretionGO:00510471400.045
cardiac chamber developmentGO:000320510.045
regulation of nervous system developmentGO:00519602640.045
regulation of potassium ion transportGO:0043266290.045
cyclic nucleotide metabolic processGO:0009187800.044
single organism carbohydrate metabolic processGO:00447231180.044
cellular response to endogenous stimulusGO:00714953770.044
cyclic purine nucleotide metabolic processGO:0052652620.043
startle responseGO:000196420.043
positive regulation of rna metabolic processGO:00512542030.043
steroid metabolic processGO:0008202730.043
developmental process involved in reproductionGO:00030061590.042
purine containing compound biosynthetic processGO:0072522850.042
positive regulation of nucleotide metabolic processGO:0045981910.042
actin filament based movementGO:0030048160.042
positive regulation of endocytosisGO:0045807280.042
cellular protein localizationGO:00346131220.041
apoptotic processGO:00069153810.041
myeloid leukocyte mediated immunityGO:0002444120.041
regulation of amine transportGO:0051952540.041
response to estradiolGO:00323551640.040
adult locomotory behaviorGO:000834440.040
negative regulation of cell communicationGO:00106481580.040
positive regulation of exocytosisGO:0045921190.040
response to mechanical stimulusGO:00096121340.040
cellular response to abiotic stimulusGO:0071214850.040
melanocyte differentiationGO:003031820.039
response to campGO:0051591910.039
Rat
g protein coupled purinergic receptor signaling pathwayGO:003558880.039
regulation of stress activated protein kinase signaling cascadeGO:0070302230.039
regulation of camp biosynthetic processGO:0030817380.039
taxisGO:0042330670.039
regulation of transporter activityGO:0032409500.039
regulation of kinase activityGO:00435491170.038
steroid biosynthetic processGO:0006694480.038
response to cytokineGO:00340972150.038
regulation of protein metabolic processGO:00512462890.038
regulation of cellular amine metabolic processGO:003323880.038
detection of external stimulusGO:0009581130.037
axis specificationGO:000979840.037
positive regulation of phagocytosis engulfmentGO:006010040.037
smooth muscle contractionGO:0006939370.037
regulation of phosphate metabolic processGO:00192203490.036
visual perceptionGO:000760130.036
regulation of response to stressGO:00801341260.036
organophosphate metabolic processGO:00196373700.036
regulation of homeostatic processGO:00328441010.036
sensory perception of light stimulusGO:005095330.036
nucleobase containing small molecule metabolic processGO:00550863160.035
carbohydrate metabolic processGO:00059751300.035
regulation of camp metabolic processGO:0030814430.035
catecholamine secretionGO:0050432330.035
organelle localizationGO:0051640550.035
regulation of transmembrane transportGO:00347621220.035
leukocyte degranulationGO:0043299120.035
neuron apoptotic processGO:0051402880.035
cell growthGO:00160491040.034
regulation of striated muscle contractionGO:0006942210.034
carboxylic acid transportGO:00469421150.034
tissue morphogenesisGO:0048729220.034
nucleotide biosynthetic processGO:0009165980.034
response to nicotineGO:0035094510.034
cell communication involved in cardiac conductionGO:008606520.033
regulation of synaptic vesicle endocytosisGO:190024210.033
cellular lipid metabolic processGO:00442552080.033
regulation of amino acid transportGO:0051955250.033
positive regulation of synaptic transmission gabaergicGO:003223090.033
development of primary female sexual characteristicsGO:0046545560.033
oxoacid metabolic processGO:00434362900.033
vasodilationGO:0042311440.033
single organism catabolic processGO:00447122830.033
carbohydrate derivative biosynthetic processGO:19011371240.033
sodium ion homeostasisGO:0055078230.032
catecholamine transportGO:0051937370.032
regulation of actin filament based processGO:0032970420.032
regulation of synaptic transmissionGO:00508041410.032
eye developmentGO:0001654500.032
g protein coupled glutamate receptor signaling pathwayGO:000721680.032
multicellular organismal response to stressGO:0033555250.032
response to histamineGO:003477630.032
regulation of membrane potentialGO:00423911100.032
response to hydrogen peroxideGO:0042542890.032
calcium ion transmembrane transportGO:0070588700.032
positive regulation of leukocyte degranulationGO:004330240.032
cellular response to growth factor stimulusGO:00713631620.031
positive regulation of hormone secretionGO:0046887650.031
regulation of excretionGO:0044062210.031
positive regulation of adenylate cyclase activityGO:0045762120.031
calcium ion transport into cytosolGO:0060402380.030
catabolic processGO:00090563510.030
calcium mediated signalingGO:0019722230.030
protein tetramerizationGO:0051262380.030
regulation of hormone levelsGO:00108171870.030
organic hydroxy compound transportGO:0015850770.030
release of sequestered calcium ion into cytosolGO:0051209250.030
negative regulation of phosphorus metabolic processGO:0010563800.030
regulation of intracellular transportGO:0032386650.030
positive regulation of synaptic vesicle recyclingGO:190342310.029
camp biosynthetic processGO:0006171470.029
positive regulation of synaptic vesicle endocytosisGO:190024410.029
negative regulation of neuron apoptotic processGO:0043524450.029
negative regulation of protein phosphorylationGO:0001933440.029
embryonic pattern specificationGO:000988010.029
regulation of receptor activityGO:0010469290.029
phenol containing compound metabolic processGO:0018958300.029
cellular catabolic processGO:00442482950.028
positive regulation of calcium ion transportGO:0051928360.028
negative regulation of amine transportGO:0051953240.028
positive regulation of cellular component movementGO:00512721020.028
behavioral response to ethanolGO:004814910.028
hormone metabolic processGO:0042445690.028
regulation of protein localizationGO:0032880810.028
ribose phosphate biosynthetic processGO:0046390870.028
chemosensory behaviorGO:000763520.028
amine transportGO:0015837570.028
cardiac muscle cell contractionGO:0086003100.028
regulation of cyclic nucleotide biosynthetic processGO:0030802450.028
muscle cell proliferationGO:0033002840.028
oxidation reduction processGO:00551143040.028
cell activation involved in immune responseGO:0002263160.027
smooth muscle cell proliferationGO:0048659770.027
positive regulation of neurotransmitter secretionGO:000195690.027
regulation of nucleotide metabolic processGO:00061401170.027
regulation of vascular smooth muscle contractionGO:000305630.027
gamete generationGO:00072761240.027
cardiovascular system developmentGO:00723581340.027
rhythmic synaptic transmissionGO:006002410.027
autonomic nervous system developmentGO:004848330.027
cellular response to ketoneGO:1901655510.027
axonogenesisGO:0007409710.026
positive regulation of synaptic vesicle exocytosisGO:200030230.026
negative regulation of transcription dna templatedGO:00458921160.026
cell cycle processGO:0022402570.026
cerebellar cortex formationGO:002169720.026
response to acid chemicalGO:00011012220.026
positive regulation of neurogenesisGO:00507691650.026
positive regulation of cell proliferationGO:00082842490.026
axon developmentGO:0061564960.026
positive regulation of cellular amino acid metabolic processGO:004576410.026
peptide transportGO:0015833970.025
peptide secretionGO:0002790860.025
organic substance catabolic processGO:19015753160.025
negative regulation of cell proliferationGO:00082851190.025
regulation of protein serine threonine kinase activityGO:0071900640.025
regulation of phagocytosis engulfmentGO:006009940.025
regulation of lipid metabolic processGO:0019216680.025
response to calcium ionGO:0051592590.025
positive regulation of cellular component organizationGO:00511302000.025
regulation of purine nucleotide biosynthetic processGO:1900371460.025
regulation of renal sodium excretionGO:0035813200.025
protein secretionGO:0009306340.025
cardiac ventricle developmentGO:000323110.025
negative regulation of phosphate metabolic processGO:0045936800.024
positive regulation of leukocyte mediated immunityGO:0002705130.024
positive regulation of phosphorylationGO:00423271770.024
purinergic receptor signaling pathwayGO:0035587100.024
olfactory behaviorGO:004204820.024
adult behaviorGO:0030534160.024
ribonucleotide biosynthetic processGO:0009260850.024
cell motilityGO:00488702020.024
presynaptic membrane assemblyGO:009710530.024
negative regulation of epinephrine secretionGO:003281160.024
catecholamine biosynthetic processGO:004242390.024
development of primary sexual characteristicsGO:00451371070.024
positive regulation of renal sodium excretionGO:0035815100.024
cardiac muscle cell action potentialGO:008600150.024
negative regulation of sequestering of calcium ionGO:0051283250.024
positive regulation of muscle contractionGO:0045933220.023
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.023
regulation of neuron projection developmentGO:00109751610.023
positive regulation of catalytic activityGO:00430851840.023
mitotic cell cycle processGO:1903047350.023
response to painGO:0048265110.023
norepinephrine secretionGO:0048243160.023
behaviorGO:00076102050.023
immune responseGO:00069551040.023
positive regulation of neural precursor cell proliferationGO:2000179100.023
regulation of release of sequestered calcium ion into cytosolGO:0051279180.023
positive regulation of cellular amine metabolic processGO:003324030.023
positive regulation of insulin secretionGO:0032024360.022
glutamate secretionGO:0014047190.022
cell morphogenesis involved in neuron differentiationGO:00486671060.022
response to manganese ionGO:0010042130.022
response to metal ionGO:00100382530.022
regulation of respiratory gaseous exchangeGO:004357620.022
cellular response to organonitrogen compoundGO:00714171970.022
negative regulation of collagen biosynthetic processGO:003296640.022
locomotor rhythmGO:004547510.022
positive regulation of camp mediated signalingGO:004395020.022

Pfkfb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.131
nervous system diseaseDOID:86300.131
cardiovascular system diseaseDOID:128700.066
central nervous system diseaseDOID:33100.043
sensory system diseaseDOID:005015500.041
eye diseaseDOID:561400.041
eye and adnexa diseaseDOID:149200.041
long qt syndromeDOID:284300.028
inherited metabolic disorderDOID:65500.027
disease of metabolismDOID:001466700.027
brain diseaseDOID:93600.025