Rattus norvegicus

18 known processes

Phka1

phosphorylase kinase, alpha 1

(Aliases: Pcyt1b)

Phka1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.259
inorganic cation transmembrane transportGO:00986622020.237
negative regulation of signalingGO:00230571570.188
transmembrane transportGO:00550854120.184
cellular response to organonitrogen compoundGO:00714171970.176
carboxylic acid metabolic processGO:00197522890.161
cellular response to organic cyclic compoundGO:00714072020.159
inorganic ion transmembrane transportGO:00986602290.151
regulation of signal transductionGO:00099663180.145
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.139
response to peptide hormoneGO:00434342780.139
macromolecule localizationGO:00330362520.137
oxoacid metabolic processGO:00434362900.135
response to peptideGO:19016522920.127
regulation of cellular localizationGO:00603412630.124
protein targetingGO:0006605610.118
tissue developmentGO:00098882520.117
carbohydrate metabolic processGO:00059751300.115
rna metabolic processGO:00160704060.115
cellular response to nitrogen compoundGO:19016992100.111
cell cell signalingGO:00072673350.110
cell cycleGO:00070491010.106
cation transportGO:00068123820.101
cellular macromolecule localizationGO:00707271220.100
single organism intracellular transportGO:19025821660.098
regenerationGO:00310991630.097
intracellular signal transductionGO:00355563140.096
protein phosphorylationGO:00064683450.091
blood circulationGO:00080151830.090
central nervous system developmentGO:00074173110.089
cellular response to endogenous stimulusGO:00714953770.088
intracellular transportGO:00469071850.087
cellular component assemblyGO:00226073600.087
protein complex biogenesisGO:00702712630.086
single organism carbohydrate metabolic processGO:00447231180.086
response to monosaccharideGO:00342841590.085
regulation of cellular ketone metabolic processGO:0010565270.084
heart processGO:0003015570.084
endoplasmic reticulum to cytosol transportGO:190351340.083
cellular protein localizationGO:00346131220.082
response to carbohydrateGO:00097431830.082
gland developmentGO:00487321550.081
positive regulation of intracellular signal transductionGO:19025331380.080
cellular response to hormone stimulusGO:00328702470.080
positive regulation of response to stimulusGO:00485842850.080
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.078
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.077
sarcoplasmic reticulum calcium ion transportGO:007029680.076
response to insulinGO:00328681330.076
regulation of intracellular signal transductionGO:19025312180.076
metal ion transportGO:00300012890.075
macromolecular complex subunit organizationGO:00439333390.074
regulation of ion transportGO:00432692450.073
response to glucoseGO:00097491360.072
programmed cell deathGO:00125013920.072
regulation of protein metabolic processGO:00512462890.071
mapk cascadeGO:00001651400.071
establishment of protein localization to organelleGO:0072594440.070
rna biosynthetic processGO:00327743800.069
positive regulation of cell communicationGO:00106472710.069
organic substance catabolic processGO:19015753160.068
cellular amino acid metabolic processGO:00065201070.068
organelle organizationGO:00069962660.068
oxidation reduction processGO:00551143040.067
establishment of protein localizationGO:00451841410.066
response to corticosteroidGO:00319602350.065
intracellular protein transportGO:0006886790.064
cellular response to insulin stimulusGO:0032869810.064
gliogenesisGO:0042063930.062
cellular response to oxygen containing compoundGO:19017013860.062
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.061
positive regulation of signal transductionGO:00099671750.061
glycogen metabolic processGO:0005977230.060
cellular component movementGO:00069282480.060
regulation of protein serine threonine kinase activityGO:0071900640.060
organophosphate metabolic processGO:00196373700.060
anion transportGO:00068201780.059
positive regulation of biosynthetic processGO:00098913190.058
camp metabolic processGO:0046058630.058
cardiac conductionGO:006133720.058
regulation of molecular functionGO:00650093980.057
positive regulation of signalingGO:00230562700.057
positive regulation of phosphate metabolic processGO:00459372620.057
single organism catabolic processGO:00447122830.057
positive regulation of nervous system developmentGO:00519621780.056
positive regulation of transcription dna templatedGO:00458931970.056
regulation of rna biosynthetic processGO:20011413810.055
localization of cellGO:00516742020.055
enzyme linked receptor protein signaling pathwayGO:00071671160.055
generation of precursor metabolites and energyGO:0006091620.055
positive regulation of cellular component organizationGO:00511302000.054
regulation of cell projection organizationGO:00313441750.053
regulation of muscle system processGO:0090257790.053
cellular glucan metabolic processGO:0006073230.053
protein transportGO:00150311320.053
response to hexoseGO:00097461440.052
negative regulation of cell communicationGO:00106481580.052
positive regulation of nucleobase containing compound metabolic processGO:00459353190.052
nucleic acid templated transcriptionGO:00976593790.052
regulation of hormone levelsGO:00108171870.051
regulation of anatomical structure morphogenesisGO:00226031410.051
regulation of cellular amine metabolic processGO:003323880.051
cellular chemical homeostasisGO:00550822470.051
glucan metabolic processGO:0044042230.050
regulation of phosphate metabolic processGO:00192203490.048
cellular component biogenesisGO:00440853680.048
regulation of mapk cascadeGO:00434081160.048
single organism reproductive processGO:00447022970.048
response to woundingGO:00096112540.048
positive regulation of cell motilityGO:2000147970.048
cellular ketone metabolic processGO:0042180510.047
regulation of metal ion transportGO:00109591180.047
muscle system processGO:00030121150.047
regulation of programmed cell deathGO:00430673410.047
regulation of multicellular organismal developmentGO:20000263760.046
protein complex assemblyGO:00064612630.046
signal transduction by phosphorylationGO:00230141440.045
amine metabolic processGO:0009308380.045
regulation of cellular amino acid metabolic processGO:000652120.045
response to estrogenGO:00436272320.045
positive regulation of rna biosynthetic processGO:19026801970.044
monovalent inorganic cation transportGO:00156721720.044
cell motilityGO:00488702020.044
regulation of cellular component organizationGO:00511283680.043
positive regulation of transportGO:00510502450.043
cytoplasmic transportGO:00164821150.043
single organism biosynthetic processGO:00447113420.043
vesicle mediated transportGO:00161921810.042
cellular catabolic processGO:00442482950.042
protein homooligomerizationGO:0051260910.042
ribonucleotide metabolic processGO:00092592310.041
regulation of phosphorylationGO:00423252480.041
cell projection organizationGO:00300303020.040
defense responseGO:00069521940.040
positive regulation of cellular biosynthetic processGO:00313282950.040
fatty acid metabolic processGO:0006631990.040
cellular lipid metabolic processGO:00442552080.040
nucleoside phosphate metabolic processGO:00067532830.040
cellular amine metabolic processGO:0044106380.039
single organism cellular localizationGO:19025801020.039
positive regulation of cell deathGO:00109421840.039
cellular response to peptide hormone stimulusGO:00713751200.038
positive regulation of catalytic activityGO:00430851840.038
response to ketoneGO:19016541820.038
ion transmembrane transportGO:00342203650.038
behaviorGO:00076102050.038
regulation of ryanodine sensitive calcium release channel activityGO:006031450.037
catabolic processGO:00090563510.037
reproductive processGO:00224143720.037
cardiac muscle cell contractionGO:0086003100.037
cell communication involved in cardiac conductionGO:008606520.037
response to lipopolysaccharideGO:00324961910.037
polysaccharide metabolic processGO:0005976250.037
positive regulation of multicellular organismal processGO:00512403870.037
cell migrationGO:00164771970.036
positive regulation of phosphorus metabolic processGO:00105622620.036
response to molecule of bacterial originGO:00022371940.036
response to glucocorticoidGO:00513842230.036
metal ion homeostasisGO:00550651860.036
cation homeostasisGO:00550801950.036
transcription dna templatedGO:00063513770.036
regulation of nucleic acid templated transcriptionGO:19035063800.036
ribonucleotide catabolic processGO:00092611360.035
positive regulation of macromolecule biosynthetic processGO:00105572470.035
positive regulation of camp biosynthetic processGO:0030819280.035
negative regulation of transportGO:00510511360.035
regulation of cell motilityGO:20001451310.035
regulation of transcription dna templatedGO:00063553740.035
negative regulation of cell proliferationGO:00082851190.035
organic acid transportGO:00158491160.034
regulation of catalytic activityGO:00507903040.034
positive regulation of cell projection organizationGO:00313461110.034
regulation of phosphorus metabolic processGO:00511743490.034
regulation of protein phosphorylationGO:00019321830.034
negative regulation of metabolic processGO:00098923310.033
response to extracellular stimulusGO:00099913800.033
small gtpase mediated signal transductionGO:0007264360.033
negative regulation of response to stimulusGO:00485851550.033
response to nutrient levelsGO:00316673700.033
regulation of protein transportGO:0051223680.032
cellular polysaccharide metabolic processGO:0044264230.032
salivary gland developmentGO:000743130.032
regulation of cell migrationGO:00303341280.032
hormone transportGO:00099141210.031
ribose phosphate metabolic processGO:00196932350.031
immune system processGO:00023762040.031
membrane depolarization during action potentialGO:008601010.031
cellular response to cytokine stimulusGO:00713451270.031
regulation of cellular protein metabolic processGO:00322682670.031
response to bacteriumGO:00096172000.031
lipid biosynthetic processGO:00086101280.031
regulation of cell differentiationGO:00455953200.031
positive regulation of secretionGO:00510471400.030
actin filament based processGO:0030029860.030
regulation of hydrolase activityGO:00513361430.030
regulation of cellular component movementGO:00512701500.030
protein complex subunit organizationGO:00718223020.030
positive regulation of developmental processGO:00510942830.030
regulation of blood circulationGO:19035221100.030
reproductionGO:00000032450.030
negative regulation of multicellular organismal processGO:00512412030.030
cellular carbohydrate metabolic processGO:0044262720.030
positive regulation of nitrogen compound metabolic processGO:00511733340.029
embryonic neurocranium morphogenesisGO:004870220.029
nitrogen compound transportGO:00717052290.029
ras protein signal transductionGO:0007265290.029
circulatory system developmentGO:00723591340.029
multicellular organismal reproductive processGO:00486092330.029
peptide secretionGO:0002790860.029
regulation of system processGO:00440572080.029
regulation of transcription from rna polymerase ii promoterGO:00063572340.029
regulation of transferase activityGO:00513381230.029
neuron projection developmentGO:00311752730.029
regulation of cell proliferationGO:00421273590.029
proteolysisGO:00065081750.029
positive regulation of cell differentiationGO:00455972170.028
calcium ion homeostasisGO:00550741620.028
negative regulation of molecular functionGO:00440921330.028
immune responseGO:00069551040.028
chemotaxisGO:0006935660.028
response to hypoxiaGO:00016662310.028
carboxylic acid transportGO:00469421150.028
regulation of peptide hormone secretionGO:0090276800.027
regulation of purine nucleotide metabolic processGO:19005421150.027
purine nucleoside metabolic processGO:00422781690.027
rhythmic processGO:00485111560.027
regulation of peptide secretionGO:0002791820.027
lipid metabolic processGO:00066292830.027
macromolecular complex assemblyGO:00650032730.027
cell morphogenesisGO:00009021420.027
positive regulation of phosphorylationGO:00423271770.027
positive regulation of cellular amine metabolic processGO:003324030.027
organonitrogen compound biosynthetic processGO:19015661670.027
nucleobase containing small molecule metabolic processGO:00550863160.027
response to growth factorGO:00708481890.027
positive regulation of gene expressionGO:00106282440.027
cellular response to stressGO:00335542690.026
regulation of anatomical structure sizeGO:00900661350.026
glucose metabolic processGO:0006006520.026
regulation of rna metabolic processGO:00512523910.026
negative regulation of signal transductionGO:0009968830.026
response to acid chemicalGO:00011012220.026
single organism organelle organizationGO:19025891800.026
glial cell differentiationGO:0010001650.026
purine ribonucleotide catabolic processGO:00091541360.026
response to biotic stimulusGO:00096072260.026
ribonucleoside metabolic processGO:00091191740.025
cellular homeostasisGO:00197252520.025
retinal ganglion cell axon guidanceGO:003129010.025
negative regulation of nitrogen compound metabolic processGO:00511721610.025
protein oligomerizationGO:00512591910.025
nucleotide metabolic processGO:00091172790.025
heterocycle catabolic processGO:00467001670.025
apoptotic processGO:00069153810.024
negative regulation of macromolecule metabolic processGO:00106052600.024
sex differentiationGO:00075481130.024
epithelium developmentGO:0060429960.024
heart developmentGO:0007507720.024
neuron projection morphogenesisGO:00488121220.024
regulation of cell growthGO:0001558850.024
cell growthGO:00160491040.024
cation transmembrane transportGO:00986552630.024
positive regulation of purine nucleotide metabolic processGO:1900544910.024
sodium ion transportGO:0006814820.024
response to tumor necrosis factorGO:0034612560.024
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.023
ventricular cardiac muscle cell action potentialGO:008600520.023
secretionGO:00469033070.023
monosaccharide metabolic processGO:0005996610.023
mesoderm developmentGO:000749820.023
intracellular receptor signaling pathwayGO:0030522350.023
glycosyl compound metabolic processGO:19016571820.023
hexose metabolic processGO:0019318580.023
regulation of neuron differentiationGO:00456642080.022
regulation of jnk cascadeGO:0046328190.022
cellular ion homeostasisGO:00068731840.022
peptidyl amino acid modificationGO:00181931260.022
response to other organismGO:00517072200.022
response to external biotic stimulusGO:00432072210.022
positive regulation of molecular functionGO:00440932300.022
regulation of dendrite developmentGO:0050773590.022
taxisGO:0042330670.022
carbohydrate derivative metabolic processGO:19011353460.022
positive regulation of neuron differentiationGO:00456661260.022
sodium ion transmembrane transportGO:0035725670.022
purine ribonucleotide metabolic processGO:00091502270.022
cellular response to peptideGO:19016531330.022
regulation of canonical wnt signaling pathwayGO:006082840.022
response to cytokineGO:00340972150.022
purine ribonucleoside metabolic processGO:00461281680.022
regulation of cellular catabolic processGO:00313291010.021
peptide hormone secretionGO:0030072840.021
positive regulation of locomotionGO:00400171020.021
regulation of nervous system developmentGO:00519602640.021
negative regulation of apoptotic processGO:00430661810.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
organophosphate catabolic processGO:00464341480.021
single organism nuclear importGO:1902593350.021
response to decreased oxygen levelsGO:00362932370.021
purine containing compound catabolic processGO:00725231380.021
organophosphate biosynthetic processGO:00904071430.021
cellular metal ion homeostasisGO:00068751720.021
multicellular organism growthGO:003526410.021
anatomical structure morphogenesisGO:00096532980.021
neuron differentiationGO:00301823680.021
hormone secretionGO:00468791150.021
cellular cation homeostasisGO:00300031800.021
multi organism reproductive processGO:00447032620.021
peptide transportGO:0015833970.021
regulation of map kinase activityGO:0043405530.020
action potentialGO:0001508540.020
liver developmentGO:0001889900.020
neuron developmentGO:00486662860.020
regulation of protein kinase activityGO:00458591050.020
transmission of nerve impulseGO:0019226420.020
regulation of locomotionGO:00400121480.020
synaptic transmissionGO:00072682350.020
ion homeostasisGO:00508012120.020
positive regulation of nucleic acid templated transcriptionGO:19035081970.020
cellular modified amino acid biosynthetic processGO:0042398180.020
multicellular organismal signalingGO:0035637440.020
cell part morphogenesisGO:00329901230.020
wound healingGO:00420601220.020
regulation of insulin secretionGO:0050796650.020
monocarboxylic acid transportGO:0015718520.020
regulation of hormone secretionGO:00468831060.020
jnk cascadeGO:0007254280.020
response to activityGO:0014823730.020
guanosine containing compound catabolic processGO:1901069710.020
potassium ion transmembrane transportGO:0071805710.020
homeostatic processGO:00425923310.020
regulation of membrane potentialGO:00423911100.019
innate immune responseGO:0045087350.019
membrane depolarization during cardiac muscle cell action potentialGO:008601210.019
aromatic compound catabolic processGO:00194391680.019
endocytosisGO:0006897840.019
response to campGO:0051591910.019
carboxylic acid biosynthetic processGO:0046394830.019
protein tetramerizationGO:0051262380.019
secretion by cellGO:00329402480.019
single organism carbohydrate catabolic processGO:0044724400.019
response to mechanical stimulusGO:00096121340.019
cellular component morphogenesisGO:00329891550.019
positive regulation of protein metabolic processGO:00512471780.019
cardiac muscle contractionGO:0060048270.019
cytosolic calcium ion homeostasisGO:00514801400.019
actin filament based movementGO:0030048160.019
muscle contractionGO:0006936880.019
membrane organizationGO:0061024940.019
anion transmembrane transportGO:0098656770.019
golgi vesicle transportGO:0048193220.019
carboxylic acid catabolic processGO:0046395490.019
reactive oxygen species biosynthetic processGO:190340980.019
nucleobase containing compound catabolic processGO:00346551520.019
positive regulation of cell developmentGO:00107201760.019
regulation of apoptotic processGO:00429813350.019
negative regulation of insulin receptor signaling pathwayGO:0046627100.019
nucleotide catabolic processGO:00091661390.019
regulation of transmembrane transportGO:00347621220.019
positive regulation of hydrolase activityGO:0051345860.019
amide transportGO:00428861050.018
sequestering of metal ionGO:005123890.018
regulation of peptide transportGO:0090087870.018
protein importGO:0017038370.018
glycogen biosynthetic processGO:0005978150.018
monocarboxylic acid metabolic processGO:00327871520.018
calcium mediated signalingGO:0019722230.018
cardiac muscle cell action potentialGO:008600150.018
cellular response to tumor necrosis factorGO:0071356460.018
small molecule biosynthetic processGO:00442831240.018
carbohydrate biosynthetic processGO:0016051420.018
response to osmotic stressGO:0006970420.018
protein homotetramerizationGO:0051289250.018
locomotionGO:00400112370.018
regulation of membrane repolarizationGO:006030610.018
positive regulation of map kinase activityGO:0043406460.018
cellular response to steroid hormone stimulusGO:0071383930.018
regulation of ion homeostasisGO:2000021630.017
cytoskeleton organizationGO:00070101110.017
circulatory system processGO:00030131830.017
alpha amino acid catabolic processGO:1901606200.017
regulation of stress activated protein kinase signaling cascadeGO:0070302230.017
energy reserve metabolic processGO:0006112250.017
positive regulation of nucleotide metabolic processGO:0045981910.017
regulation of neurogenesisGO:00507672470.017
cellular calcium ion homeostasisGO:00068741600.017
organ regenerationGO:00311001010.017
mesoderm morphogenesisGO:004833210.017
regulation of protein localizationGO:0032880810.017
response to vitaminGO:00332731310.017
purine nucleotide metabolic processGO:00061632290.017
insulin secretionGO:0030073690.017
regulation of cell developmentGO:00602842630.017
sequestering of calcium ionGO:005120880.017
chemical homeostasisGO:00488782920.017
smooth muscle cell proliferationGO:0048659770.017
alpha amino acid metabolic processGO:1901605710.017
regulation of protein modification processGO:00313991940.017
developmental process involved in reproductionGO:00030061590.017
lipid localizationGO:0010876620.016
regulation of neuron projection developmentGO:00109751610.016
phospholipid metabolic processGO:0006644610.016
regulation of reactive oxygen species biosynthetic processGO:190342650.016
cellular response to corticosteroid stimulusGO:0071384690.016
peptidyl serine phosphorylationGO:0018105330.016
organic cyclic compound catabolic processGO:19013611750.016
agingGO:00075682410.016
nucleoside metabolic processGO:00091161790.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.016
negative regulation of intracellular estrogen receptor signaling pathwayGO:003314720.016
negative regulation of programmed cell deathGO:00430691830.016
response to estradiolGO:00323551640.016
response to ethanolGO:00454711620.016
protein localizationGO:00081041910.016
regulation of intracellular transportGO:0032386650.016
organic anion transportGO:00157111320.016
regulation of anion transportGO:0044070430.016
positive regulation of ion transportGO:0043270940.016
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.016
alcohol metabolic processGO:0006066770.016
gastrulationGO:000736920.016
heart contractionGO:0060047570.016
cardiac chamber developmentGO:000320510.016
protein targeting to nucleusGO:0044744350.016
cardiovascular system developmentGO:00723581340.016
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
purine nucleoside triphosphate catabolic processGO:00091461220.015
purine containing compound biosynthetic processGO:0072522850.015
nucleoside phosphate biosynthetic processGO:19012931020.015
divalent inorganic cation homeostasisGO:00725071650.015
protein heterooligomerizationGO:0051291890.015
divalent metal ion transportGO:00708381320.015
cell cycle processGO:0022402570.015
positive regulation of protein modification processGO:00314011420.015
hepaticobiliary system developmentGO:0061008900.015
locomotor rhythmGO:004547510.015
muscle tissue developmentGO:0060537580.015
nucleotide biosynthetic processGO:0009165980.015
dendrite developmentGO:0016358720.015
gtp catabolic processGO:0006184710.015
protein autophosphorylationGO:0046777660.015
negative regulation of developmental processGO:00510931250.015
negative regulation of protein metabolic processGO:00512481140.015
multicellular organism reproductionGO:00325042330.015
regulation of purine nucleotide catabolic processGO:0033121650.015
positive regulation of neurogenesisGO:00507691650.015
ribonucleoside triphosphate catabolic processGO:00092031220.015
regulation of gluconeogenesisGO:000611140.015
purine nucleotide biosynthetic processGO:0006164830.015
ribose phosphate biosynthetic processGO:0046390870.015
negative regulation of secretionGO:0051048820.015
positive regulation of nucleotide catabolic processGO:0030813530.015
regulation of secretionGO:00510462240.015
mammary gland developmentGO:0030879380.015
striated muscle tissue developmentGO:0014706580.015
positive regulation of programmed cell deathGO:00430681570.015
response to phGO:0009268270.015
regulation of transporter activityGO:0032409500.015
negative regulation of hormone secretionGO:0046888460.015
morphogenesis of embryonic epitheliumGO:001633130.014
positive regulation of intracellular transportGO:0032388390.014
organic acid catabolic processGO:0016054490.014
positive regulation of mapk cascadeGO:0043410920.014
positive regulation of neuron projection developmentGO:0010976990.014
carbohydrate derivative biosynthetic processGO:19011371240.014
positive regulation of transferase activityGO:0051347810.014
reproductive structure developmentGO:00486081280.014
negative regulation of gene expressionGO:00106291990.014
cardiac muscle cell action potential involved in contractionGO:008600220.014
protein processingGO:0016485680.014
cellular response to abiotic stimulusGO:0071214850.014
organic acid biosynthetic processGO:0016053830.014
response to metal ionGO:00100382530.014
positive regulation of rna metabolic processGO:00512542030.014
fatty acid catabolic processGO:0009062260.014
prostaglandin secretionGO:003231060.014
muscle structure developmentGO:0061061870.014
purine ribonucleoside catabolic processGO:00461301240.014
regulation of heart contractionGO:0008016480.014
reactive nitrogen species metabolic processGO:200105710.014
positive regulation of protein phosphorylationGO:00019341350.014
cellular nitrogen compound catabolic processGO:00442701630.014
positive regulation of transcription factor import into nucleusGO:004299340.014
regulation of release of sequestered calcium ion into cytosolGO:0051279180.014
cell projection morphogenesisGO:00488581230.014
vesicle localizationGO:0051648330.014

Phka1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.060
inherited metabolic disorderDOID:65500.051
carbohydrate metabolic disorderDOID:297800.038
disease of cellular proliferationDOID:1456600.029
cancerDOID:16200.029
disease of anatomical entityDOID:700.022
nervous system diseaseDOID:86300.022
organ system cancerDOID:005068600.020
central nervous system diseaseDOID:33100.016