Rattus norvegicus

28 known processes

C1s

complement component 1, s subcomponent

(Aliases: r-gsp)

C1s biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
complement activationGO:0006956110.995
response to inorganic substanceGO:00100353770.795
protein activation cascadeGO:0072376120.770
response to cytokineGO:00340972150.742
response to lipopolysaccharideGO:00324961910.714
coagulationGO:0050817280.663
fibrinolysisGO:004273020.623
response to molecule of bacterial originGO:00022371940.570
negative regulation of innate immune responseGO:004582440.524
positive regulation of blood coagulationGO:003019440.521
tissue developmentGO:00098882520.491
response to nutrient levelsGO:00316673700.461
blood coagulationGO:0007596260.453
negative regulation of fibrinolysisGO:005191820.447
response to cobalt ionGO:0032025120.390
regulation of response to stressGO:00801341260.363
response to woundingGO:00096112540.318
regulation of blood coagulationGO:003019390.313
kidney developmentGO:0001822670.310
tissue remodelingGO:0048771400.299
response to metal ionGO:00100382530.295
defense responseGO:00069521940.293
regulation of coagulationGO:0050818110.266
protein processingGO:0016485680.255
response to other organismGO:00517072200.239
positive regulation of hemostasisGO:190004840.236
hemostasisGO:0007599260.212
positive regulation of neuron projection developmentGO:0010976990.210
regulation of wound healingGO:0061041140.209
response to external biotic stimulusGO:00432072210.201
protein maturationGO:0051604680.199
regulation of hydrolase activityGO:00513361430.198
cellular response to vascular endothelial growth factor stimulusGO:003592460.188
cellular response to cytokine stimulusGO:00713451270.187
innate immune responseGO:0045087350.181
wound healingGO:00420601220.174
activation of immune responseGO:0002253260.168
regulation of locomotionGO:00400121480.164
positive regulation of wound healingGO:009030360.160
regulation of neuron deathGO:19012141150.157
regulation of catalytic activityGO:00507903040.150
negative regulation of humoral immune responseGO:000292140.147
regulation of acute inflammatory responseGO:0002673230.140
programmed cell deathGO:00125013920.136
cellular response to organic cyclic compoundGO:00714072020.134
renal system developmentGO:0072001670.127
negative regulation of multicellular organismal processGO:00512412030.127
regulation of transcription dna templatedGO:00063553740.126
negative regulation of macromolecule metabolic processGO:00106052600.119
regulation of immune system processGO:00026821230.116
cell projection morphogenesisGO:00488581230.116
neuron deathGO:00709971270.112
immune responseGO:00069551040.108
neurological system processGO:00508772190.107
reproductive structure developmentGO:00486081280.105
negative regulation of metabolic processGO:00098923310.104
immune system processGO:00023762040.102
rna metabolic processGO:00160704060.102
response to retinoic acidGO:0032526630.101
immune effector processGO:0002252530.101
positive regulation of response to stimulusGO:00485842850.101
cellular response to oxygen containing compoundGO:19017013860.100
acute inflammatory responseGO:0002526580.098
response to glucoseGO:00097491360.098
hepaticobiliary system developmentGO:0061008900.097
response to estradiolGO:00323551640.093
response to interferon gammaGO:0034341200.093
respiratory system developmentGO:0060541450.092
intracellular signal transductionGO:00355563140.092
regulation of protein maturationGO:1903317500.091
negative regulation of hemostasisGO:190004760.090
response to monosaccharideGO:00342841590.087
response to biotic stimulusGO:00096072260.087
response to dexamethasoneGO:0071548490.085
homeostatic processGO:00425923310.083
positive regulation of cellular protein metabolic processGO:00322701670.079
regulation of body fluid levelsGO:0050878900.079
response to glucocorticoidGO:00513842230.078
rna biosynthetic processGO:00327743800.078
inflammatory responseGO:00069541500.075
urogenital system developmentGO:0001655780.072
regulation of multicellular organismal developmentGO:20000263760.072
cellular response to steroid hormone stimulusGO:0071383930.071
response to vitamin kGO:003257140.071
regulation of cellular component movementGO:00512701500.069
response to bacteriumGO:00096172000.069
positive regulation of immune system processGO:0002684900.068
regulation of cellular protein metabolic processGO:00322682670.066
reproductive processGO:00224143720.066
response to carbohydrateGO:00097431830.064
sensory organ developmentGO:0007423740.061
regulation of proteolysisGO:0030162660.061
negative regulation of response to woundingGO:1903035230.061
regulation of rna metabolic processGO:00512523910.060
glycosyl compound catabolic processGO:19016581260.060
liver developmentGO:0001889900.060
response to extracellular stimulusGO:00099913800.058
neuron projection developmentGO:00311752730.057
positive regulation of phosphorus metabolic processGO:00105622620.057
single organism reproductive processGO:00447022970.056
protein phosphorylationGO:00064683450.056
eye morphogenesisGO:004859240.055
positive regulation of cell projection organizationGO:00313461110.055
response to nutrientGO:00075842480.054
cellular response to corticosteroid stimulusGO:0071384690.053
organic substance catabolic processGO:19015753160.053
cellular catabolic processGO:00442482950.052
cellular response to biotic stimulusGO:0071216590.052
response to hexoseGO:00097461440.052
negative regulation of response to external stimulusGO:0032102370.052
neuron developmentGO:00486662860.051
locomotionGO:00400112370.051
multicellular organism reproductionGO:00325042330.050
peptidyl amino acid modificationGO:00181931260.050
regulation of phosphate metabolic processGO:00192203490.050
negative regulation of wound healingGO:006104580.049
regulation of axonogenesisGO:0050770370.048
positive regulation of gene expressionGO:00106282440.047
enzyme linked receptor protein signaling pathwayGO:00071671160.047
cellular response to lipidGO:00713962010.046
chemical homeostasisGO:00488782920.046
anatomical structure morphogenesisGO:00096532980.046
regulation of phosphorylationGO:00423252480.046
positive regulation of phosphate metabolic processGO:00459372620.045
response to interferon betaGO:003545610.044
regulation of protein metabolic processGO:00512462890.043
reproductionGO:00000032450.043
regulation of response to external stimulusGO:00321011060.042
metal ion homeostasisGO:00550651860.042
regulation of rna biosynthetic processGO:20011413810.042
regulation of viral entry into host cellGO:004659630.042
carbohydrate derivative metabolic processGO:19011353460.042
regulation of immune responseGO:0050776550.042
regulation of cell projection organizationGO:00313441750.041
multicellular organismal reproductive processGO:00486092330.041
regulation of molecular functionGO:00650093980.041
viral gene expressionGO:001908020.041
positive regulation of phosphorylationGO:00423271770.041
positive regulation of nervous system developmentGO:00519621780.038
negative regulation of endothelial cell migrationGO:001059630.037
cellular response to growth factor stimulusGO:00713631620.037
humoral immune responseGO:0006959120.037
cell projection organizationGO:00300303020.036
response to estrogenGO:00436272320.036
regulation of nucleic acid templated transcriptionGO:19035063800.036
cellular chemical homeostasisGO:00550822470.036
viral genome replicationGO:001907920.036
regulation of cell differentiationGO:00455953200.035
negative regulation of apoptotic processGO:00430661810.035
regulation of hemostasisGO:190004690.035
organ regenerationGO:00311001010.034
cellular response to dexamethasone stimulusGO:0071549360.034
regulation of phosphorus metabolic processGO:00511743490.034
transcription dna templatedGO:00063513770.034
behaviorGO:00076102050.034
rhythmic processGO:00485111560.033
organ morphogenesisGO:0009887750.033
regulation of cellular component organizationGO:00511283680.033
transmembrane transportGO:00550854120.032
negative regulation of peptidase activityGO:0010466380.032
positive regulation of neuron differentiationGO:00456661260.032
negative regulation of response to stimulusGO:00485851550.032
regulation of nervous system developmentGO:00519602640.032
negative regulation of cell deathGO:00605482290.032
positive regulation of cellular biosynthetic processGO:00313282950.031
cellular response to endogenous stimulusGO:00714953770.031
morphogenesis of a polarized epitheliumGO:000173810.031
cellular response to alcoholGO:0097306870.031
regulation of erk1 and erk2 cascadeGO:0070372410.031
cellular component movementGO:00069282480.031
localization of cellGO:00516742020.031
agingGO:00075682410.030
negative regulation of endopeptidase activityGO:0010951360.030
cellular response to hexose stimulusGO:0071331650.030
carbohydrate homeostasisGO:0033500750.030
signal transduction by phosphorylationGO:00230141440.029
cellular response to molecule of bacterial originGO:0071219560.029
cellular homeostasisGO:00197252520.029
negative regulation of gene expressionGO:00106291990.029
reactive oxygen species metabolic processGO:0072593370.029
regulation of immune effector processGO:0002697320.029
developmental process involved in reproductionGO:00030061590.029
lipid metabolic processGO:00066292830.028
brain renin angiotensin systemGO:000203530.028
response to corticosteroidGO:00319602350.027
reproductive system developmentGO:00614581280.027
aromatic compound catabolic processGO:00194391680.027
organonitrogen compound catabolic processGO:19015651790.026
regulation of protein activation cascadeGO:200025760.026
glycosyl compound metabolic processGO:19016571820.026
regulation of neurogenesisGO:00507672470.026
regulation of neuron projection developmentGO:00109751610.026
negative regulation of protein processingGO:0010955470.025
negative regulation of programmed cell deathGO:00430691830.025
regulation of cell proliferationGO:00421273590.025
catabolic processGO:00090563510.025
negative regulation of viral processGO:004852540.025
heterocycle catabolic processGO:00467001670.024
response to interferon alphaGO:003545510.024
regulation of protein processingGO:0070613500.024
sex differentiationGO:00075481130.024
positive regulation of nucleobase containing compound metabolic processGO:00459353190.024
positive regulation of nitrogen compound metabolic processGO:00511733340.024
cellular amine metabolic processGO:0044106380.023
single organism biosynthetic processGO:00447113420.023
cellular response to cobalt ionGO:007127930.023
positive regulation of biosynthetic processGO:00098913190.023
multi multicellular organism processGO:00447061380.023
positive regulation of hydrolase activityGO:0051345860.023
epithelium developmentGO:0060429960.022
cellular response to hormone stimulusGO:00328702470.022
cellular response to retinoic acidGO:0071300270.022
response to interleukin 1GO:0070555550.022
axonogenesisGO:0007409710.021
regulation of cell activationGO:0050865500.021
negative regulation of developmental processGO:00510931250.021
negative regulation of proteolysisGO:0045861410.021
organic cyclic compound catabolic processGO:19013611750.021
proteolysisGO:00065081750.021
Human Rat
organic acid metabolic processGO:00060822920.020
response to mechanical stimulusGO:00096121340.020
cellular response to stressGO:00335542690.020
positive regulation of protein metabolic processGO:00512471780.020
positive regulation of cellular component organizationGO:00511302000.020
positive regulation of multicellular organismal processGO:00512403870.020
phosphatidylethanolamine metabolic processGO:004633710.020
regulation of neuron differentiationGO:00456642080.020
negative regulation of epithelial cell migrationGO:001063340.020
tissue morphogenesisGO:0048729220.020
cardiovascular system developmentGO:00723581340.020
anterior posterior pattern specificationGO:000995210.019
response to peptideGO:19016522920.019
regulation of protein modification processGO:00313991940.019
negative regulation of immune system processGO:0002683390.019
response to campGO:0051591910.019
regulation of proteasomal protein catabolic processGO:006113640.019
negative regulation of cellular protein metabolic processGO:00322691060.019
development of primary male sexual characteristicsGO:0046546590.019
regulation of apoptotic processGO:00429813350.019
regulation of innate immune responseGO:0045088150.019
negative regulation of molecular functionGO:00440921330.018
negative regulation of locomotionGO:0040013410.018
negative regulation of protein metabolic processGO:00512481140.018
regulation of cellular ketone metabolic processGO:0010565270.018
response to tumor necrosis factorGO:0034612560.018
cognitionGO:0050890920.018
metanephric glomerulus morphogenesisGO:007227510.018
regulation of defense responseGO:0031347680.018
negative regulation of rna metabolic processGO:00512531230.018
response to aluminum ionGO:0010044100.018
nucleobase containing small molecule metabolic processGO:00550863160.018
regenerationGO:00310991630.018
p38mapk cascadeGO:003806610.017
regulation of heart morphogenesisGO:200082620.017
response to ketoneGO:19016541820.017
single organism carbohydrate catabolic processGO:0044724400.017
regulation of cell morphogenesis involved in differentiationGO:0010769720.017
transcription from rna polymerase ii promoterGO:00063662520.017
cellular response to external stimulusGO:00714961180.017
inflammatory cell apoptotic processGO:000692550.017
regulation of reactive oxygen species metabolic processGO:2000377260.017
nucleobase containing compound catabolic processGO:00346551520.016
cell motilityGO:00488702020.016
positive regulation of cell developmentGO:00107201760.016
brain developmentGO:00074202470.016
regulation of endopeptidase activityGO:0052548510.016
single organism catabolic processGO:00447122830.016
cell migrationGO:00164771970.016
blood coagulation fibrin clot formationGO:007237810.016
ovulation cycleGO:0042698670.016
positive regulation of neurogenesisGO:00507691650.016
macromolecule localizationGO:00330362520.016
regulation of complement activationGO:003044960.015
vasculature developmentGO:0001944700.015
response to transition metal nanoparticleGO:19902671220.015
cellular response to mechanical stimulusGO:0071260480.015
response to amino acidGO:0043200750.015
negative regulation of protein maturationGO:1903318470.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
nucleoside metabolic processGO:00091161790.015
response to ethanolGO:00454711620.015
single organism behaviorGO:00447081300.015
positive regulation of cell differentiationGO:00455972170.015
organophosphate metabolic processGO:00196373700.015
positive regulation of molecular functionGO:00440932300.014
endocytosisGO:0006897840.014
gland developmentGO:00487321550.014
circulatory system developmentGO:00723591340.014
leukocyte mediated immunityGO:0002443280.014
vascular endothelial growth factor signaling pathwayGO:003808440.014
amine metabolic processGO:0009308380.014
head developmentGO:00603222470.014
negative regulation of immune responseGO:0050777150.014
cellular response to extracellular stimulusGO:0031668730.014
response to acetateGO:001003430.014
cellular response to reactive oxygen speciesGO:0034614550.014
maternal process involved in female pregnancyGO:0060135380.014
negative regulation of cellular metabolic processGO:00313242810.014
regulation of programmed cell deathGO:00430673410.014
multi organism reproductive processGO:00447032620.014
response to decreased oxygen levelsGO:00362932370.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
multicellular organismal signalingGO:0035637440.013
ribose phosphate metabolic processGO:00196932350.013
response to growth factorGO:00708481890.013
peptidyl tyrosine modificationGO:0018212720.013
ribonucleotide metabolic processGO:00092592310.013
positive regulation of transportGO:00510502450.013
mapk cascadeGO:00001651400.013
positive regulation of catalytic activityGO:00430851840.013
cellular response to inorganic substanceGO:0071241650.013
positive regulation of immune responseGO:0050778420.013
growthGO:00400071650.013
proteoglycan metabolic processGO:000602930.012
response to hypoxiaGO:00016662310.012
nuclear transportGO:0051169490.012
negative regulation of coagulationGO:005081970.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
cellular glucose homeostasisGO:0001678660.012
regulation of p38mapk cascadeGO:190074410.012
negative regulation of canonical wnt signaling pathwayGO:009009040.012
respiratory tube developmentGO:0030323430.012
vesicle mediated transportGO:00161921810.012
viral transcriptionGO:001908320.012
renin secretion into blood streamGO:000200110.012
nucleoside triphosphate metabolic processGO:00091411440.012
oxoacid metabolic processGO:00434362900.012
positive regulation of developmental processGO:00510942830.012
lung developmentGO:0030324430.012
negative regulation of signalingGO:00230571570.012
cell morphogenesis involved in differentiationGO:00009041190.012
purine nucleotide metabolic processGO:00061632290.012
cation homeostasisGO:00550801950.011
regulation of anatomical structure morphogenesisGO:00226031410.011
regulation of peptidase activityGO:0052547550.011
cell part morphogenesisGO:00329901230.011
purine containing compound metabolic processGO:00725212530.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
intramembranous ossificationGO:000195710.011
negative regulation of catalytic activityGO:00430861030.011
neuron apoptotic processGO:0051402880.011
ras protein signal transductionGO:0007265290.011
striated muscle tissue developmentGO:0014706580.011
ossificationGO:0001503700.011
skeletal system developmentGO:0001501410.011
activation of cysteine type endopeptidase activity involved in apoptotic processGO:000691940.011
metal ion transportGO:00300012890.011
rho protein signal transductionGO:0007266110.011
tissue homeostasisGO:0001894280.011
positive regulation of macromolecule biosynthetic processGO:00105572470.010
positive regulation of transcription dna templatedGO:00458931970.010
embryonic skeletal system developmentGO:004870630.010
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.010
response to vitamin dGO:0033280340.010
gonad developmentGO:00084061040.010
negative regulation of cell differentiationGO:0045596990.010
reactive nitrogen species metabolic processGO:200105710.010
muscle tissue developmentGO:0060537580.010
neuron differentiationGO:00301823680.010
sensory perceptionGO:00076001010.010

C1s disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.106
integumentary system diseaseDOID:1600.106
eye and adnexa diseaseDOID:149200.045
nervous system diseaseDOID:86300.045
eye diseaseDOID:561400.045
sensory system diseaseDOID:005015500.045
anemiaDOID:235500.041
hematopoietic system diseaseDOID:7400.041
hemolytic anemiaDOID:58300.041
normocytic anemiaDOID:72000.041
immune system diseaseDOID:291400.041
retinal degenerationDOID:846600.035
retinal diseaseDOID:567900.035
age related macular degenerationDOID:1087100.018
degeneration of macula and posterior poleDOID:200700.018
macular degenerationDOID:444800.018
skin diseaseDOID:3700.018
connective tissue diseaseDOID:6500.014
musculoskeletal system diseaseDOID:1700.014