Rattus norvegicus

38 known processes

Mdh1

malate dehydrogenase 1, NAD (soluble)

(Aliases: Mor2,MDL1,Mdhl)

Mdh1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neurotransmitter uptakeGO:000150430.932
oxidation reduction processGO:00551143040.874
nucleoside monophosphate metabolic processGO:0009123930.873
purine nucleoside triphosphate metabolic processGO:00091441410.859
organophosphate metabolic processGO:00196373700.822
positive regulation of atp biosynthetic processGO:200117120.817
nucleotide metabolic processGO:00091172790.804
purine ribonucleoside monophosphate metabolic processGO:0009167840.749
nucleobase containing small molecule metabolic processGO:00550863160.733
nucleoside triphosphate metabolic processGO:00091411440.703
porphyrin containing compound biosynthetic processGO:000677960.697
aerobic respirationGO:0009060130.689
purine ribonucleoside triphosphate metabolic processGO:00092051400.652
adenine nucleotide transportGO:005150320.616
ribonucleotide metabolic processGO:00092592310.612
cofactor metabolic processGO:0051186950.600
nucleoside phosphate metabolic processGO:00067532830.600
ribonucleoside monophosphate metabolic processGO:0009161880.593
organonitrogen compound biosynthetic processGO:19015661670.584
porphyrin containing compound metabolic processGO:000677880.549
electron transport chainGO:002290050.537
purine nucleotide metabolic processGO:00061632290.535
purine nucleoside monophosphate metabolic processGO:0009126840.518
atp metabolic processGO:0046034720.518
ribonucleoside metabolic processGO:00091191740.501
purine nucleoside diphosphate biosynthetic processGO:000913690.499
purine nucleoside metabolic processGO:00422781690.495
purine ribonucleoside metabolic processGO:00461281680.482
cofactor biosynthetic processGO:0051188280.482
purine nucleoside monophosphate biosynthetic processGO:0009127200.464
tetrapyrrole biosynthetic processGO:003301470.463
l glutamate importGO:005193820.461
single organism biosynthetic processGO:00447113420.458
purine nucleoside biosynthetic processGO:0042451210.454
organophosphate biosynthetic processGO:00904071430.448
regulation of atp biosynthetic processGO:200116920.435
ribose phosphate metabolic processGO:00196932350.429
nucleoside metabolic processGO:00091161790.407
purine ribonucleotide metabolic processGO:00091502270.405
tetrapyrrole metabolic processGO:0033013110.395
purine containing compound metabolic processGO:00725212530.390
organic acid metabolic processGO:00060822920.385
ribonucleoside triphosphate metabolic processGO:00091991410.385
heme biosynthetic processGO:000678340.370
glycosyl compound metabolic processGO:19016571820.357
apoptotic mitochondrial changesGO:0008637100.341
purine ribonucleoside diphosphate biosynthetic processGO:000918090.322
purine nucleoside diphosphate metabolic processGO:000913590.317
oxidative phosphorylationGO:000611940.303
nucleoside transportGO:001585880.284
nucleotide biosynthetic processGO:0009165980.276
acidic amino acid transportGO:0015800100.266
cellular respirationGO:0045333210.266
carbohydrate derivative metabolic processGO:19011353460.261
purine ribonucleotide biosynthetic processGO:0009152810.249
purine nucleotide biosynthetic processGO:0006164830.226
action potentialGO:0001508540.211
atp catabolic processGO:0006200540.205
adp transportGO:001586610.200
monovalent inorganic cation transportGO:00156721720.191
positive regulation of cellular biosynthetic processGO:00313282950.190
nucleoside monophosphate biosynthetic processGO:0009124280.186
anion transportGO:00068201780.183
generation of precursor metabolites and energyGO:0006091620.183
dicarboxylic acid metabolic processGO:0043648420.177
oxoacid metabolic processGO:00434362900.161
adult locomotory behaviorGO:000834440.156
regulation of nucleotide biosynthetic processGO:0030808470.155
anion transmembrane transportGO:0098656770.154
carboxylic acid metabolic processGO:00197522890.146
organic acid transportGO:00158491160.143
ribonucleoside monophosphate catabolic processGO:0009158550.137
purine ribonucleoside biosynthetic processGO:0046129210.135
programmed necrotic cell deathGO:009730020.135
regulation of programmed cell deathGO:00430673410.134
glycosyl compound catabolic processGO:19016581260.132
inorganic ion transmembrane transportGO:00986602290.130
dicarboxylic acid transportGO:0006835340.127
energy derivation by oxidation of organic compoundsGO:0015980460.123
ribonucleoside triphosphate catabolic processGO:00092031220.118
purine nucleotide transportGO:001586530.111
ribonucleoside biosynthetic processGO:0042455250.104
regulation of necroptotic processGO:006054420.104
organic anion transportGO:00157111320.095
cofactor transportGO:005118150.094
ribonucleotide catabolic processGO:00092611360.094
vesicle mediated transportGO:00161921810.093
apoptotic processGO:00069153810.093
cellular chemical homeostasisGO:00550822470.092
purine containing compound catabolic processGO:00725231380.091
transmembrane transportGO:00550854120.091
purine nucleoside triphosphate catabolic processGO:00091461220.090
nadh metabolic processGO:0006734100.089
organophosphate catabolic processGO:00464341480.089
response to nutrientGO:00075842480.088
synaptic vesicle localizationGO:0097479240.088
purine ribonucleoside monophosphate biosynthetic processGO:0009168200.085
regulation of purine nucleotide metabolic processGO:19005421150.085
ribonucleoside diphosphate biosynthetic processGO:0009188100.083
adp biosynthetic processGO:000617280.083
purine ribonucleotide catabolic processGO:00091541360.083
positive regulation of nucleotide biosynthetic processGO:0030810360.083
pigment biosynthetic processGO:004614840.079
carbohydrate derivative biosynthetic processGO:19011371240.079
response to interleukin 1GO:0070555550.079
behaviorGO:00076102050.079
mitochondrial calcium ion homeostasisGO:005156030.077
single organism catabolic processGO:00447122830.076
ion homeostasisGO:00508012120.076
positive regulation of nitrogen compound metabolic processGO:00511733340.076
regulation of apoptotic processGO:00429813350.075
cation homeostasisGO:00550801950.073
purine containing compound biosynthetic processGO:0072522850.071
positive regulation of purine nucleotide biosynthetic processGO:1900373360.070
tricarboxylic acid metabolic processGO:0072350100.070
protein heterooligomerizationGO:0051291890.069
cellular ion homeostasisGO:00068731840.068
monocarboxylic acid metabolic processGO:00327871520.068
positive regulation of purine nucleotide metabolic processGO:1900544910.067
adp metabolic processGO:004603180.066
ribonucleotide biosynthetic processGO:0009260850.066
ribose phosphate biosynthetic processGO:0046390870.066
necroptotic processGO:007026620.066
nad metabolic processGO:0019674150.065
lipid biosynthetic processGO:00086101280.065
regulation of ion transportGO:00432692450.064
syncytium formation by plasma membrane fusionGO:000076830.063
regulation of transporter activityGO:0032409500.062
locomotionGO:00400112370.062
regulation of phosphate metabolic processGO:00192203490.060
heterocycle catabolic processGO:00467001670.060
organic cyclic compound catabolic processGO:19013611750.059
positive regulation of phosphate metabolic processGO:00459372620.057
positive regulation of molecular functionGO:00440932300.056
single organism behaviorGO:00447081300.056
nucleoside phosphate catabolic processGO:19012921400.056
amino acid transportGO:0006865700.055
alditol metabolic processGO:001940040.055
response to oxidative stressGO:00069791860.055
nucleotide catabolic processGO:00091661390.054
l amino acid transportGO:0015807210.054
regulation of purine nucleotide biosynthetic processGO:1900371460.054
organelle localizationGO:0051640550.053
chemical homeostasisGO:00488782920.053
cellular nitrogen compound catabolic processGO:00442701630.053
regulation of nucleotide metabolic processGO:00061401170.052
calcium ion homeostasisGO:00550741620.052
positive regulation of apoptotic processGO:00430651540.051
purine ribonucleoside monophosphate catabolic processGO:0009169550.051
regulation of membrane potentialGO:00423911100.051
purine nucleoside triphosphate biosynthetic processGO:000914560.051
purine nucleoside catabolic processGO:00061521240.050
ribonucleoside triphosphate biosynthetic processGO:000920170.049
l glutamate transportGO:001581370.049
cellular cation homeostasisGO:00300031800.049
organonitrogen compound catabolic processGO:19015651790.049
pigment metabolic processGO:004244070.048
response to decreased oxygen levelsGO:00362932370.048
cellular metal ion homeostasisGO:00068751720.048
programmed cell deathGO:00125013920.047
cation transmembrane transportGO:00986552630.047
circulatory system developmentGO:00723591340.047
metal ion homeostasisGO:00550651860.047
organelle organizationGO:00069962660.047
single organism reproductive processGO:00447022970.046
response to transition metal nanoparticleGO:19902671220.046
cellular amino acid biosynthetic processGO:0008652320.046
synapse organizationGO:0050808460.045
catabolic processGO:00090563510.045
citrate metabolic processGO:000610130.045
anatomical structure formation involved in morphogenesisGO:0048646830.043
purine ribonucleoside triphosphate catabolic processGO:00092071220.043
vesicle localizationGO:0051648330.043
negative regulation of hydrogen peroxide metabolic processGO:001072720.041
divalent inorganic cation homeostasisGO:00725071650.041
regulation of cell proliferationGO:00421273590.040
nucleoside monophosphate catabolic processGO:0009125560.040
nucleoside biosynthetic processGO:0009163250.040
ribonucleoside diphosphate metabolic processGO:0009185100.039
growthGO:00400071650.039
gamete generationGO:00072761240.039
positive regulation of transmembrane transportGO:0034764250.039
glycosyl compound biosynthetic processGO:1901659250.039
pyridine containing compound metabolic processGO:0072524320.039
cellular component assemblyGO:00226073600.038
nucleoside phosphate biosynthetic processGO:19012931020.037
organic substance catabolic processGO:19015753160.037
establishment of organelle localizationGO:0051656370.037
cellular component biogenesisGO:00440853680.037
organic hydroxy compound metabolic processGO:19016151150.037
ribonucleoside catabolic processGO:00424541260.036
nucleoside triphosphate catabolic processGO:00091431230.036
neuron apoptotic processGO:0051402880.036
positive regulation of nucleotide metabolic processGO:0045981910.035
purine nucleotide catabolic processGO:00061951360.035
positive regulation of biosynthetic processGO:00098913190.035
lipid localizationGO:0010876620.035
positive regulation of transportGO:00510502450.034
atp synthesis coupled electron transportGO:004277320.034
response to organophosphorusGO:00466831020.034
regulation of molecular functionGO:00650093980.034
cellular calcium ion homeostasisGO:00068741600.034
establishment of vesicle localizationGO:0051650310.033
aromatic compound catabolic processGO:00194391680.033
neurotransmitter transportGO:0006836420.033
reproductive processGO:00224143720.033
single organism intracellular transportGO:19025821660.032
response to ethanolGO:00454711620.032
nicotinamide nucleotide metabolic processGO:0046496280.032
purine ribonucleoside catabolic processGO:00461301240.032
sulfur compound metabolic processGO:0006790700.032
positive regulation of nucleobase containing compound metabolic processGO:00459353190.032
macromolecular complex subunit organizationGO:00439333390.032
cellular homeostasisGO:00197252520.032
cellular divalent inorganic cation homeostasisGO:00725031620.031
nucleoside catabolic processGO:00091641260.031
synapse assemblyGO:0007416290.031
developmental growthGO:00485891000.031
multicellular organism reproductionGO:00325042330.031
aspartate family amino acid biosynthetic processGO:000906740.031
regulation of transmembrane transporter activityGO:0022898490.030
developmental process involved in reproductionGO:00030061590.030
negative regulation of cell deathGO:00605482290.030
response to nutrient levelsGO:00316673700.029
rna metabolic processGO:00160704060.028
regulation of transmembrane transportGO:00347621220.028
regulation of hormone levelsGO:00108171870.028
cellular lipid metabolic processGO:00442552080.028
cellular response to oxygen containing compoundGO:19017013860.027
response to extracellular stimulusGO:00099913800.027
regulation of phosphorus metabolic processGO:00511743490.027
cytosolic calcium ion homeostasisGO:00514801400.026
response to cytokineGO:00340972150.026
positive regulation of ion transportGO:0043270940.026
l amino acid importGO:004309250.026
multi organism reproductive processGO:00447032620.026
response to hypoxiaGO:00016662310.026
oxaloacetate metabolic processGO:000610760.026
positive regulation of cell communicationGO:00106472710.025
lipid metabolic processGO:00066292830.024
multicellular organismal reproductive processGO:00486092330.024
central nervous system developmentGO:00074173110.024
intracellular signal transductionGO:00355563140.024
locomotory behaviorGO:0007626150.024
amino acid importGO:004309070.024
sulfur compound biosynthetic processGO:0044272190.024
hippocampus developmentGO:0021766300.024
nucleoside triphosphate biosynthetic processGO:000914280.024
inorganic cation transmembrane transportGO:00986622020.023
small molecule biosynthetic processGO:00442831240.023
urogenital system developmentGO:0001655780.023
cellular component movementGO:00069282480.022
cellular response to organic cyclic compoundGO:00714072020.022
regulation of reactive oxygen species metabolic processGO:2000377260.022
hormone transportGO:00099141210.021
cellular response to ketoneGO:1901655510.021
muscle cell cellular homeostasisGO:004671610.021
establishment of synaptic vesicle localizationGO:0097480230.021
protein complex subunit organizationGO:00718223020.020
lipid storageGO:001991510.020
cellular response to organonitrogen compoundGO:00714171970.020
synaptic growth at neuromuscular junctionGO:005112410.019
cellular hormone metabolic processGO:0034754490.019
synaptic vesicle transportGO:0048489230.019
multi multicellular organism processGO:00447061380.019
negative regulation of programmed cell deathGO:00430691830.019
myoblast fusionGO:000752020.019
response to toxic substanceGO:00096361330.019
regulation of signal transductionGO:00099663180.019
hormone metabolic processGO:0042445690.019
regulation of nucleoside metabolic processGO:0009118660.019
positive regulation of programmed cell deathGO:00430681570.019
negative regulation of apoptotic processGO:00430661810.019
response to hexoseGO:00097461440.019
regulation of cellular localizationGO:00603412630.018
adult behaviorGO:0030534160.018
alcohol biosynthetic processGO:0046165380.018
negative regulation of developmental processGO:00510931250.018
reproductionGO:00000032450.018
activation of cysteine type endopeptidase activityGO:009720240.018
positive regulation of phosphorus metabolic processGO:00105622620.018
organic acid biosynthetic processGO:0016053830.018
cell cell signaling involved in cell fate commitmentGO:004516820.017
Fly
secretion by cellGO:00329402480.017
renal system developmentGO:0072001670.017
response to purine containing compoundGO:00140741260.017
cellular response to endogenous stimulusGO:00714953770.017
multicellular organismal signalingGO:0035637440.017
regulation of catalytic activityGO:00507903040.017
anatomical structure morphogenesisGO:00096532980.017
positive regulation of response to stimulusGO:00485842850.017
regulation of secretionGO:00510462240.016
response to other organismGO:00517072200.016
alpha amino acid biosynthetic processGO:1901607230.016
regulation of neurotransmitter levelsGO:0001505420.016
lactate metabolic processGO:000608930.016
cellular response to nitrogen compoundGO:19016992100.016
cell type specific apoptotic processGO:00972851340.016
anatomical structure homeostasisGO:0060249290.016
macromolecular complex assemblyGO:00650032730.016
cation transportGO:00068123820.016
alpha amino acid catabolic processGO:1901606200.016
nucleoside diphosphate metabolic processGO:0009132140.016
positive regulation of cell proliferationGO:00082842490.016
fatty acid metabolic processGO:0006631990.016
carboxylic acid biosynthetic processGO:0046394830.016
positive regulation of cellular protein metabolic processGO:00322701670.016
sexual reproductionGO:00199531480.016
g protein coupled receptor signaling pathwayGO:00071862420.016
synaptic transmissionGO:00072682350.016
agingGO:00075682410.015
ion transmembrane transportGO:00342203650.015
purine ribonucleoside diphosphate metabolic processGO:000917990.015
homeostatic processGO:00425923310.015
positive regulation of secretion by cellGO:19035321280.015
muscle structure developmentGO:0061061870.015
regulation of smooth muscle cell proliferationGO:0048660750.015
norepinephrine metabolic processGO:004241530.015
carboxylic acid transportGO:00469421150.015
nucleotide transportGO:000686240.015
development of primary female sexual characteristicsGO:0046545560.014
response to ammonium ionGO:0060359710.014
regulation of multicellular organismal developmentGO:20000263760.014
reactive oxygen species biosynthetic processGO:190340980.014
cellular catabolic processGO:00442482950.014
membrane organizationGO:0061024940.014
organic acid catabolic processGO:0016054490.014
metal ion transportGO:00300012890.014
nitrogen compound transportGO:00717052290.014
regulation of atp metabolic processGO:190357890.014
response to peptide hormoneGO:00434342780.013
cell cell signalingGO:00072673350.013
Fly
positive regulation of signalingGO:00230562700.013
connective tissue developmentGO:0061448330.013
muscle cell differentiationGO:0042692520.013
cell adhesionGO:00071551100.013
substrate dependent cell migrationGO:000692910.013
intracellular transportGO:00469071850.013
response to peptideGO:19016522920.013
negative regulation of biosynthetic processGO:00098901680.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
alditol biosynthetic processGO:001940140.013
organic hydroxy compound biosynthetic processGO:1901617510.013
male gamete generationGO:0048232990.013
negative regulation of cell communicationGO:00106481580.013
cellular amine metabolic processGO:0044106380.013
carbohydrate metabolic processGO:00059751300.013
tricarboxylic acid cycleGO:0006099110.012
negative regulation of transportGO:00510511360.012
cardiovascular system developmentGO:00723581340.012
regulation of hydrolase activityGO:00513361430.012
purine ribonucleotide transportGO:001586830.012
alcohol metabolic processGO:0006066770.012
negative regulation of cellular metabolic processGO:00313242810.012
cellular amino acid metabolic processGO:00065201070.012
acrosome assemblyGO:000167530.012
ribonucleoside monophosphate biosynthetic processGO:0009156240.012
response to starvationGO:0042594590.012
regulation of intracellular signal transductionGO:19025312180.012
positive regulation of intracellular signal transductionGO:19025331380.012
protein oligomerizationGO:00512591910.012
response to hydrogen peroxideGO:0042542890.012
glutamine family amino acid biosynthetic processGO:000908420.012
response to fungicideGO:0060992200.011
positive regulation of signal transductionGO:00099671750.011
osteoblast differentiationGO:0001649260.011
mesoderm developmentGO:000749820.011
response to oxygen levelsGO:00704822650.011
cold acclimationGO:000963110.011
coenzyme metabolic processGO:0006732860.011
positive regulation of cellular amine metabolic processGO:003324030.011
positive regulation of gene expressionGO:00106282440.011
single organism carbohydrate metabolic processGO:00447231180.011
regulation of mitochondrial membrane permeabilityGO:004690250.011
negative regulation of mitochondrion organizationGO:001082320.011
inorganic anion transmembrane transportGO:0098661350.011
regulation of neurogenesisGO:00507672470.011
mitotic sister chromatid separationGO:005130610.011
spermatogenesisGO:0007283990.011
regulation of apoptotic signaling pathwayGO:2001233130.011
response to glucoseGO:00097491360.010
positive regulation of protein metabolic processGO:00512471780.010
protein complex assemblyGO:00064612630.010
cellular response to lipidGO:00713962010.010
excretionGO:0007588240.010
response to acid chemicalGO:00011012220.010
ossificationGO:0001503700.010
regulation of organelle organizationGO:0033043800.010
lipid transportGO:0006869610.010
regulation of peptide secretionGO:0002791820.010

Mdh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
amino acid metabolic disorderDOID:925200.032
inherited metabolic disorderDOID:65500.032
disease of metabolismDOID:001466700.032
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.026
cancerDOID:16200.023
disease of cellular proliferationDOID:1456600.023
central nervous system diseaseDOID:33100.022
organ system cancerDOID:005068600.018
gastrointestinal system cancerDOID:311900.012
benign neoplasmDOID:006007200.012