Rattus norvegicus

0 known processes

Hibadh

3-hydroxyisobutyrate dehydrogenase

Hibadh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.856
Human
carboxylic acid metabolic processGO:00197522890.575
Human
oxoacid metabolic processGO:00434362900.562
Human
oxidation reduction processGO:00551143040.210
Human
coenzyme metabolic processGO:0006732860.172
thioester metabolic processGO:0035383280.155
progesterone biosynthetic processGO:000670130.145
cellular polysaccharide metabolic processGO:0044264230.137
single organism catabolic processGO:00447122830.117
Human
response to extracellular stimulusGO:00099913800.097
response to nitrosative stressGO:005140920.094
response to inorganic substanceGO:00100353770.091
response to nutrient levelsGO:00316673700.087
regulation of apoptotic processGO:00429813350.083
sulfur compound metabolic processGO:0006790700.082
acyl coa metabolic processGO:0006637280.081
monocarboxylic acid metabolic processGO:00327871520.072
branched chain amino acid metabolic processGO:000908140.067
Human
programmed cell deathGO:00125013920.066
single organism biosynthetic processGO:00447113420.066
organic substance catabolic processGO:19015753160.062
Human
organophosphate metabolic processGO:00196373700.061
response to nutrientGO:00075842480.060
cofactor metabolic processGO:0051186950.059
response to reactive oxygen speciesGO:00003021200.059
cellular amino acid metabolic processGO:00065201070.058
Human
mitochondrial rna metabolic processGO:000095910.057
cellular response to oxidative stressGO:0034599760.057
organic acid biosynthetic processGO:0016053830.056
thioester biosynthetic processGO:003538470.052
response to oxygen levelsGO:00704822650.051
energy derivation by oxidation of organic compoundsGO:0015980460.048
catabolic processGO:00090563510.047
Human
cellular response to reactive oxygen speciesGO:0034614550.046
reactive oxygen species metabolic processGO:0072593370.045
sulfur compound biosynthetic processGO:0044272190.043
negative regulation of cell deathGO:00605482290.042
regulation of hormone levelsGO:00108171870.041
branched chain amino acid catabolic processGO:000908340.040
Human
agingGO:00075682410.038
response to ethanolGO:00454711620.037
cellular catabolic processGO:00442482950.037
Human
cellular amine metabolic processGO:0044106380.036
negative regulation of programmed cell deathGO:00430691830.036
acetyl coa metabolic processGO:0006084170.035
coenzyme biosynthetic processGO:0009108220.035
apoptotic processGO:00069153810.035
cold acclimationGO:000963110.033
glycogen metabolic processGO:0005977230.033
response to oxidative stressGO:00069791860.033
cellular component assemblyGO:00226073600.033
cellular response to endogenous stimulusGO:00714953770.033
amine metabolic processGO:0009308380.033
lipid metabolic processGO:00066292830.032
organelle organizationGO:00069962660.031
positive regulation of biosynthetic processGO:00098913190.031
ion homeostasisGO:00508012120.030
cellular ketone metabolic processGO:0042180510.030
regulation of programmed cell deathGO:00430673410.030
macromolecule localizationGO:00330362520.029
negative regulation of apoptotic processGO:00430661810.029
intracellular signal transductionGO:00355563140.029
cellular amino acid biosynthetic processGO:0008652320.029
cell type specific apoptotic processGO:00972851340.029
negative regulation of macromolecule metabolic processGO:00106052600.028
response to estrogenGO:00436272320.028
pyruvate metabolic processGO:0006090270.028
regulation of phosphorus metabolic processGO:00511743490.028
polysaccharide metabolic processGO:0005976250.027
regulation of cell proliferationGO:00421273590.026
carbohydrate biosynthetic processGO:0016051420.026
regulation of cellular localizationGO:00603412630.026
cation homeostasisGO:00550801950.025
positive regulation of cell proliferationGO:00082842490.025
negative regulation of metabolic processGO:00098923310.025
cellular response to oxygen containing compoundGO:19017013860.025
transcription dna templatedGO:00063513770.025
central nervous system developmentGO:00074173110.024
single organism reproductive processGO:00447022970.024
cellular glucan metabolic processGO:0006073230.024
cellular response to stressGO:00335542690.023
chemical homeostasisGO:00488782920.023
negative regulation of cellular metabolic processGO:00313242810.023
cellular protein localizationGO:00346131220.023
acyl coa biosynthetic processGO:007161670.023
response to estradiolGO:00323551640.023
cellular response to organonitrogen compoundGO:00714171970.022
cellular response to nitrogen compoundGO:19016992100.022
cellular response to insulin stimulusGO:0032869810.022
regulation of intracellular signal transductionGO:19025312180.022
response to lipopolysaccharideGO:00324961910.022
regulation of proteasomal protein catabolic processGO:006113640.022
ribonucleoside metabolic processGO:00091191740.022
regulation of cellular ketone metabolic processGO:0010565270.021
cellular hormone metabolic processGO:0034754490.021
regulation of cellular amino acid metabolic processGO:000652120.021
c21 steroid hormone biosynthetic processGO:0006700100.021
regulation of protein metabolic processGO:00512462890.021
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.020
cellular cation homeostasisGO:00300031800.020
regulation of rna biosynthetic processGO:20011413810.020
nucleic acid templated transcriptionGO:00976593790.020
response to external biotic stimulusGO:00432072210.020
cellular response to peptide hormone stimulusGO:00713751200.020
neuron apoptotic processGO:0051402880.019
nucleobase containing small molecule metabolic processGO:00550863160.019
positive regulation of molecular functionGO:00440932300.019
rna metabolic processGO:00160704060.019
negative regulation of gene expressionGO:00106291990.019
glycosyl compound metabolic processGO:19016571820.019
regulation of cellular protein metabolic processGO:00322682670.019
purine ribonucleotide metabolic processGO:00091502270.019
regulation of ion transportGO:00432692450.019
cellular lipid metabolic processGO:00442552080.019
cellular amino acid catabolic processGO:0009063210.018
Human
cellular chemical homeostasisGO:00550822470.018
single organism organelle organizationGO:19025891800.018
response to peptide hormoneGO:00434342780.018
macromolecular complex assemblyGO:00650032730.017
cellular biogenic amine metabolic processGO:0006576300.017
small molecule biosynthetic processGO:00442831240.017
response to metal ionGO:00100382530.017
regulation of protein modification processGO:00313991940.017
neurological system processGO:00508772190.017
lipid biosynthetic processGO:00086101280.017
chromosome segregationGO:000705920.017
generation of precursor metabolites and energyGO:0006091620.017
brain developmentGO:00074202470.017
glucan biosynthetic processGO:0009250150.017
response to hyperoxiaGO:0055093450.017
purine nucleotide metabolic processGO:00061632290.017
regulation of phosphorylationGO:00423252480.017
regulation of kinase activityGO:00435491170.017
regulation of transcription dna templatedGO:00063553740.016
nucleoside phosphate metabolic processGO:00067532830.016
response to hydrogen peroxideGO:0042542890.016
regulation of multicellular organismal developmentGO:20000263760.016
nucleotide metabolic processGO:00091172790.016
response to alkaloidGO:00432791320.016
kidney developmentGO:0001822670.016
positive regulation of multicellular organismal processGO:00512403870.016
regulation of cellular amine metabolic processGO:003323880.016
positive regulation of cellular amine metabolic processGO:003324030.016
cell projection organizationGO:00300303020.016
response to glucocorticoidGO:00513842230.016
neuron developmentGO:00486662860.016
cellular response to peptideGO:19016531330.016
regulation of phosphate metabolic processGO:00192203490.015
nitrogen compound transportGO:00717052290.015
response to toxic substanceGO:00096361330.015
cellular response to hormone stimulusGO:00328702470.015
head developmentGO:00603222470.015
metal ion homeostasisGO:00550651860.015
succinate metabolic processGO:000610570.015
neuron differentiationGO:00301823680.015
organic hydroxy compound metabolic processGO:19016151150.015
peptidyl amino acid modificationGO:00181931260.015
regulation of catalytic activityGO:00507903040.015
response to other organismGO:00517072200.015
protein complex subunit organizationGO:00718223020.015
cellular response to cytokine stimulusGO:00713451270.015
cellular homeostasisGO:00197252520.015
positive regulation of neurogenesisGO:00507691650.014
immune system processGO:00023762040.014
regulation of nucleic acid templated transcriptionGO:19035063800.014
regulation of molecular functionGO:00650093980.014
mitotic sister chromatid separationGO:005130610.014
regulation of rna metabolic processGO:00512523910.014
cellular metal ion homeostasisGO:00068751720.014
glucan metabolic processGO:0044042230.014
regulation of peptide transportGO:0090087870.014
tricarboxylic acid metabolic processGO:0072350100.014
positive regulation of nitrogen compound metabolic processGO:00511733340.014
anterior posterior pattern specificationGO:000995210.014
regulation of homeostatic processGO:00328441010.014
positive regulation of cellular biosynthetic processGO:00313282950.014
single organism cellular localizationGO:19025801020.014
reproductionGO:00000032450.014
carbohydrate derivative metabolic processGO:19011353460.014
purine containing compound metabolic processGO:00725212530.014
regulation of blood pressureGO:0008217830.014
energy reserve metabolic processGO:0006112250.014
regulation of neuron deathGO:19012141150.013
macromolecular complex subunit organizationGO:00439333390.013
glycogen biosynthetic processGO:0005978150.013
dephosphorylationGO:0016311980.013
transcription from rna polymerase ii promoterGO:00063662520.013
regulation of transferase activityGO:00513381230.013
hormone metabolic processGO:0042445690.013
amine catabolic processGO:000931090.013
rhythmic processGO:00485111560.013
regulation of gluconeogenesisGO:000611140.013
valine metabolic processGO:000657310.013
Human
regulation of cellular component organizationGO:00511283680.013
organic cyclic compound catabolic processGO:19013611750.013
negative regulation of protein metabolic processGO:00512481140.013
positive regulation of programmed cell deathGO:00430681570.013
dicarboxylic acid metabolic processGO:0043648420.013
cellular ion homeostasisGO:00068731840.012
protein phosphorylationGO:00064683450.012
glucose metabolic processGO:0006006520.012
positive regulation of protein phosphorylationGO:00019341350.012
neuron projection developmentGO:00311752730.012
protein complex biogenesisGO:00702712630.012
regulation of cellular catabolic processGO:00313291010.012
embryonic pattern specificationGO:000988010.012
positive regulation of protein metabolic processGO:00512471780.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
protein maturationGO:0051604680.012
protein localizationGO:00081041910.012
positive regulation of transportGO:00510502450.012
ribonucleotide metabolic processGO:00092592310.012
positive regulation of developmental processGO:00510942830.011
intracellular transportGO:00469071850.011
spindle organizationGO:000705120.011
positive regulation of apoptotic processGO:00430651540.011
multi organism reproductive processGO:00447032620.011
negative regulation of phosphorus metabolic processGO:0010563800.011
cellular polysaccharide biosynthetic processGO:0033692150.011
regulation of intracellular transportGO:0032386650.011
eye morphogenesisGO:004859240.011
multicellular organism reproductionGO:00325042330.011
negative regulation of neuron deathGO:1901215690.011
multicellular organismal reproductive processGO:00486092330.011
carboxylic acid catabolic processGO:0046395490.011
Human
response to cytokineGO:00340972150.011
muscle structure developmentGO:0061061870.011
neuron deathGO:00709971270.011
cellular response to growth factor stimulusGO:00713631620.011
cytoskeleton organizationGO:00070101110.011
fatty acid beta oxidationGO:0006635220.011
sequestering of calcium ionGO:005120880.011
response to hypoxiaGO:00016662310.011
ras protein signal transductionGO:0007265290.011
response to insulinGO:00328681330.011
ncrna processingGO:003447030.011
cognitionGO:0050890920.011
negative regulation of signalingGO:00230571570.011
urogenital system developmentGO:0001655780.011
lipid catabolic processGO:0016042460.011
blood circulationGO:00080151830.011
rna localizationGO:000640340.011
cellular response to external stimulusGO:00714961180.011
axis specificationGO:000979840.011
response to peptideGO:19016522920.011
regulation of neuron apoptotic processGO:0043523830.011
circulatory system developmentGO:00723591340.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
response to biotic stimulusGO:00096072260.011
acetyl coa biosynthetic process from pyruvateGO:000608650.010
peptide biosynthetic processGO:004304330.010
regulation of catabolic processGO:00098941130.010
tissue developmentGO:00098882520.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
glutamate metabolic processGO:000653630.010
ion transmembrane transportGO:00342203650.010
negative regulation of ion transportGO:0043271510.010
positive regulation of cellular amino acid metabolic processGO:004576410.010
ribose phosphate metabolic processGO:00196932350.010
positive regulation of cellular component organizationGO:00511302000.010
homeostatic processGO:00425923310.010
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.010
sequestering of metal ionGO:005123890.010
hexose metabolic processGO:0019318580.010

Hibadh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
amino acid metabolic disorderDOID:925200.037
inherited metabolic disorderDOID:65500.037
disease of metabolismDOID:001466700.037
disease of cellular proliferationDOID:1456600.021
organic acidemiaDOID:006015900.020
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012