Rattus norvegicus

31 known processes

Lcat

lecithin cholesterol acyltransferase

(Aliases: MGC108718)

Lcat biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell proliferationGO:00421273590.162
response to nutrient levelsGO:00316673700.139
homeostatic processGO:00425923310.125
Human
response to extracellular stimulusGO:00099913800.123
cellular response to oxygen containing compoundGO:19017013860.104
cellular response to hormone stimulusGO:00328702470.096
response to woundingGO:00096112540.093
response to peptideGO:19016522920.090
macromolecule localizationGO:00330362520.084
Human
regulation of multicellular organismal developmentGO:20000263760.072
positive regulation of cell proliferationGO:00082842490.065
organic acid metabolic processGO:00060822920.061
secretionGO:00469033070.058
response to purine containing compoundGO:00140741260.057
response to inorganic substanceGO:00100353770.057
cellular lipid metabolic processGO:00442552080.056
Human Rat
regulation of catalytic activityGO:00507903040.055
intracellular signal transductionGO:00355563140.054
anion transportGO:00068201780.054
cellular response to stressGO:00335542690.054
neurological system processGO:00508772190.053
regulation of molecular functionGO:00650093980.053
cellular response to nitrogen compoundGO:19016992100.052
negative regulation of multicellular organismal processGO:00512412030.052
cellular component biogenesisGO:00440853680.051
Mouse
cellular amino acid metabolic processGO:00065201070.051
reproductive processGO:00224143720.050
cellular component assemblyGO:00226073600.049
Mouse
response to ketoneGO:19016541820.048
transmembrane transportGO:00550854120.048
tissue developmentGO:00098882520.048
response to external biotic stimulusGO:00432072210.048
regulation of cell differentiationGO:00455953200.048
nitrogen compound transportGO:00717052290.047
response to oxygen levelsGO:00704822650.047
regulation of hydrolase activityGO:00513361430.046
neuron differentiationGO:00301823680.046
cation transportGO:00068123820.046
anatomical structure morphogenesisGO:00096532980.046
response to peptide hormoneGO:00434342780.046
agingGO:00075682410.045
programmed cell deathGO:00125013920.045
response to nutrientGO:00075842480.044
response to glucocorticoidGO:00513842230.044
multi organism reproductive processGO:00447032620.044
cell projection organizationGO:00300303020.044
inflammatory responseGO:00069541500.043
single organism biosynthetic processGO:00447113420.043
Human
positive regulation of phosphorus metabolic processGO:00105622620.042
regulation of cellular protein metabolic processGO:00322682670.042
central nervous system developmentGO:00074173110.042
positive regulation of nucleobase containing compound metabolic processGO:00459353190.042
positive regulation of nitrogen compound metabolic processGO:00511733340.041
single organism behaviorGO:00447081300.041
cellular chemical homeostasisGO:00550822470.041
cellular amine metabolic processGO:0044106380.041
Human Rat
response to corticosteroidGO:00319602350.041
response to organophosphorusGO:00466831020.041
negative regulation of cellular metabolic processGO:00313242810.041
regulation of neurogenesisGO:00507672470.040
cellular response to lipidGO:00713962010.040
regulation of nervous system developmentGO:00519602640.040
lipid biosynthetic processGO:00086101280.040
Human
carboxylic acid metabolic processGO:00197522890.040
organonitrogen compound biosynthetic processGO:19015661670.039
Human
organic hydroxy compound metabolic processGO:19016151150.039
cellular homeostasisGO:00197252520.039
liver developmentGO:0001889900.038
regenerationGO:00310991630.038
negative regulation of developmental processGO:00510931250.038
positive regulation of cell communicationGO:00106472710.038
response to metal ionGO:00100382530.038
regulation of phosphate metabolic processGO:00192203490.038
positive regulation of developmental processGO:00510942830.038
regulation of cellular component organizationGO:00511283680.037
Mouse
ion transmembrane transportGO:00342203650.037
positive regulation of nervous system developmentGO:00519621780.037
response to cytokineGO:00340972150.037
apoptotic processGO:00069153810.036
small molecule biosynthetic processGO:00442831240.036
Human
response to decreased oxygen levelsGO:00362932370.036
organonitrogen compound catabolic processGO:19015651790.036
regulation of ion transportGO:00432692450.036
amine metabolic processGO:0009308380.036
Human Rat
synaptic transmissionGO:00072682350.035
neuron projection developmentGO:00311752730.035
cellular response to organonitrogen compoundGO:00714171970.035
regulation of neuron differentiationGO:00456642080.035
response to campGO:0051591910.034
neuron developmentGO:00486662860.034
cellular response to endogenous stimulusGO:00714953770.034
purine containing compound metabolic processGO:00725212530.034
negative regulation of metabolic processGO:00098923310.033
multicellular organism reproductionGO:00325042330.033
organic hydroxy compound transportGO:0015850770.033
Human
organic substance catabolic processGO:19015753160.032
growthGO:00400071650.032
head developmentGO:00603222470.032
reproductionGO:00000032450.032
response to other organismGO:00517072200.032
response to estradiolGO:00323551640.031
multicellular organismal signalingGO:0035637440.031
lipid transportGO:0006869610.031
Human
positive regulation of catalytic activityGO:00430851840.031
negative regulation of cell deathGO:00605482290.031
carboxylic acid biosynthetic processGO:0046394830.031
positive regulation of multicellular organismal processGO:00512403870.031
positive regulation of molecular functionGO:00440932300.030
inorganic cation transmembrane transportGO:00986622020.030
behaviorGO:00076102050.030
regulation of cell developmentGO:00602842630.030
positive regulation of phosphate metabolic processGO:00459372620.030
regulation of phosphorus metabolic processGO:00511743490.030
single organism reproductive processGO:00447022970.030
chemical homeostasisGO:00488782920.030
Human
cation homeostasisGO:00550801950.030
response to acid chemicalGO:00011012220.030
nucleotide metabolic processGO:00091172790.029
brain developmentGO:00074202470.029
regulation of cellular amine metabolic processGO:003323880.029
monovalent inorganic cation transportGO:00156721720.028
transmission of nerve impulseGO:0019226420.028
cellular response to organic cyclic compoundGO:00714072020.028
regulation of secretionGO:00510462240.028
female pregnancyGO:00075651220.028
response to estrogenGO:00436272320.028
monocarboxylic acid metabolic processGO:00327871520.028
circulatory system developmentGO:00723591340.028
inorganic ion transmembrane transportGO:00986602290.028
metal ion homeostasisGO:00550651860.027
glial cell differentiationGO:0010001650.027
regulation of apoptotic processGO:00429813350.027
gliogenesisGO:0042063930.027
multicellular organismal reproductive processGO:00486092330.027
regulation of programmed cell deathGO:00430673410.026
positive regulation of biosynthetic processGO:00098913190.026
wound healingGO:00420601220.026
organic anion transportGO:00157111320.026
positive regulation of signalingGO:00230562700.025
regulation of rna biosynthetic processGO:20011413810.025
cell cell signalingGO:00072673350.025
renal system developmentGO:0072001670.025
nucleoside phosphate metabolic processGO:00067532830.025
rna biosynthetic processGO:00327743800.025
positive regulation of response to stimulusGO:00485842850.025
protein localizationGO:00081041910.025
cellular cation homeostasisGO:00300031800.025
oxoacid metabolic processGO:00434362900.025
regulation of growthGO:00400081050.025
cellular catabolic processGO:00442482950.025
lipid localizationGO:0010876620.025
Human
regulation of cellular amino acid metabolic processGO:000652120.024
positive regulation of cell deathGO:00109421840.024
regulation of signal transductionGO:00099663180.024
response to hexoseGO:00097461440.024
carbohydrate derivative metabolic processGO:19011353460.024
negative regulation of programmed cell deathGO:00430691830.024
ion homeostasisGO:00508012120.024
defense responseGO:00069521940.024
organophosphate metabolic processGO:00196373700.024
Human Rat
localization of cellGO:00516742020.024
regulation of body fluid levelsGO:0050878900.023
positive regulation of cell developmentGO:00107201760.023
cellular ketone metabolic processGO:0042180510.023
macromolecular complex assemblyGO:00650032730.023
Mouse
regulation of cellular localizationGO:00603412630.023
regulation of intracellular signal transductionGO:19025312180.023
positive regulation of cellular biosynthetic processGO:00313282950.023
response to transition metal nanoparticleGO:19902671220.023
regulation of secretion by cellGO:19035302080.023
cell growthGO:00160491040.022
response to hypoxiaGO:00016662310.022
cellular metal ion homeostasisGO:00068751720.022
cellular response to external stimulusGO:00714961180.022
protein oligomerizationGO:00512591910.022
response to mechanical stimulusGO:00096121340.022
cellular component movementGO:00069282480.022
alcohol metabolic processGO:0006066770.022
regulation of protein metabolic processGO:00512462890.022
urogenital system developmentGO:0001655780.022
regulation of hormone levelsGO:00108171870.022
nucleobase containing small molecule metabolic processGO:00550863160.022
cellular component morphogenesisGO:00329891550.021
response to vitaminGO:00332731310.021
positive regulation of cellular component organizationGO:00511302000.021
cellular amino acid catabolic processGO:0009063210.021
regulation of kinase activityGO:00435491170.021
positive regulation of neuron projection developmentGO:0010976990.021
regulation of anatomical structure morphogenesisGO:00226031410.021
catabolic processGO:00090563510.021
ribose phosphate metabolic processGO:00196932350.021
multi multicellular organism processGO:00447061380.020
g protein coupled receptor signaling pathwayGO:00071862420.020
regulation of cellular component movementGO:00512701500.020
negative regulation of gene expressionGO:00106291990.020
positive regulation of cell differentiationGO:00455972170.020
protein phosphorylationGO:00064683450.020
mesoderm developmentGO:000749820.020
heart morphogenesisGO:000300730.020
response to lipopolysaccharideGO:00324961910.020
positive regulation of cellular protein metabolic processGO:00322701670.020
gland developmentGO:00487321550.020
regulation of protein phosphorylationGO:00019321830.020
positive regulation of gene expressionGO:00106282440.020
rna metabolic processGO:00160704060.020
negative regulation of cell proliferationGO:00082851190.020
regulation of nucleic acid templated transcriptionGO:19035063800.020
cell morphogenesisGO:00009021420.019
organic acid biosynthetic processGO:0016053830.019
response to insulinGO:00328681330.019
cardiovascular system developmentGO:00723581340.019
intracellular transportGO:00469071850.019
protein complex subunit organizationGO:00718223020.019
kidney developmentGO:0001822670.019
neuronal action potentialGO:0019228350.019
cellular amino acid biosynthetic processGO:0008652320.019
neuron deathGO:00709971270.019
metal ion transportGO:00300012890.019
positive regulation of protein metabolic processGO:00512471780.019
regulation of cell growthGO:0001558850.019
regulation of neuron projection developmentGO:00109751610.019
immune system processGO:00023762040.019
oxidation reduction processGO:00551143040.019
negative regulation of protein metabolic processGO:00512481140.019
response to monosaccharideGO:00342841590.019
regulation of phosphorylationGO:00423252480.019
regulation of protein modification processGO:00313991940.019
cellular response to growth factor stimulusGO:00713631620.018
negative regulation of apoptotic processGO:00430661810.018
response to biotic stimulusGO:00096072260.018
proteolysisGO:00065081750.018
gonad developmentGO:00084061040.018
positive regulation of transportGO:00510502450.018
muscle system processGO:00030121150.018
single organism catabolic processGO:00447122830.018
sodium ion transportGO:0006814820.018
secretion by cellGO:00329402480.018
cellular response to peptideGO:19016531330.018
protein complex biogenesisGO:00702712630.017
positive regulation of cellular amine metabolic processGO:003324030.017
negative regulation of macromolecule metabolic processGO:00106052600.017
cell type specific apoptotic processGO:00972851340.017
negative regulation of response to stimulusGO:00485851550.017
positive regulation of phosphorylationGO:00423271770.017
sexual reproductionGO:00199531480.017
response to growth factorGO:00708481890.017
dephosphorylationGO:0016311980.017
response to ethanolGO:00454711620.017
negative regulation of cell developmentGO:0010721820.017
cell morphogenesis involved in differentiationGO:00009041190.017
positive regulation of purine nucleotide metabolic processGO:1900544910.017
cellular response to steroid hormone stimulusGO:0071383930.017
positive regulation of cell projection organizationGO:00313461110.017
positive regulation of secretionGO:00510471400.016
multicellular organism growthGO:003526410.016
regulation of rna metabolic processGO:00512523910.016
alpha amino acid metabolic processGO:1901605710.016
regulation of synaptic transmissionGO:00508041410.016
response to interleukin 1GO:0070555550.016
positive regulation of protein phosphorylationGO:00019341350.016
small gtpase mediated signal transductionGO:0007264360.016
ras protein signal transductionGO:0007265290.016
transcription dna templatedGO:00063513770.016
regulation of cellular ketone metabolic processGO:0010565270.016
nucleic acid templated transcriptionGO:00976593790.016
purine nucleotide metabolic processGO:00061632290.016
positive regulation of hydrolase activityGO:0051345860.016
cellular response to cytokine stimulusGO:00713451270.016
response to alkaloidGO:00432791320.016
regulation of synaptic plasticityGO:0048167700.016
cation transmembrane transportGO:00986552630.016
regulation of system processGO:00440572080.015
anion transmembrane transportGO:0098656770.015
locomotionGO:00400112370.015
regulation of cell migrationGO:00303341280.015
divalent inorganic cation transportGO:00725111340.015
cellular calcium ion homeostasisGO:00068741600.015
positive regulation of intracellular signal transductionGO:19025331380.015
blood circulationGO:00080151830.015
negative regulation of cell communicationGO:00106481580.015
feeding behaviorGO:0007631530.015
reproductive system developmentGO:00614581280.015
muscle cell proliferationGO:0033002840.015
response to bacteriumGO:00096172000.015
macromolecular complex subunit organizationGO:00439333390.015
Human Mouse
reactive oxygen species metabolic processGO:0072593370.015
regulation of cell motilityGO:20001451310.015
cellular ion homeostasisGO:00068731840.015
developmental process involved in reproductionGO:00030061590.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
cellular response to insulin stimulusGO:0032869810.015
response to molecule of bacterial originGO:00022371940.015
organic cyclic compound catabolic processGO:19013611750.015
negative regulation of cellular protein metabolic processGO:00322691060.015
astrocyte developmentGO:001400240.014
protein complex assemblyGO:00064612630.014
divalent metal ion transportGO:00708381320.014
alpha amino acid catabolic processGO:1901606200.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
ribonucleoside metabolic processGO:00091191740.014
negative regulation of molecular functionGO:00440921330.014
negative regulation of nitrogen compound metabolic processGO:00511721610.014
reproductive structure developmentGO:00486081280.014
regulation of homeostatic processGO:00328441010.014
embryonic appendage morphogenesisGO:003511340.014
muscle structure developmentGO:0061061870.014
positive regulation of neurogenesisGO:00507691650.014
hepaticobiliary system developmentGO:0061008900.014
regulation of membrane potentialGO:00423911100.014
acute inflammatory responseGO:0002526580.014
regulation of cell projection organizationGO:00313441750.014
positive regulation of signal transductionGO:00099671750.014
cell migrationGO:00164771970.014
purine ribonucleoside metabolic processGO:00461281680.014
cellular response to corticosteroid stimulusGO:0071384690.014
negative regulation of catalytic activityGO:00430861030.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.014
carbohydrate metabolic processGO:00059751300.014
organophosphate biosynthetic processGO:00904071430.014
Human
negative regulation of signalingGO:00230571570.013
neural crest cell differentiationGO:001403320.013
response to fatty acidGO:0070542650.013
regulation of transcription dna templatedGO:00063553740.013
mapk cascadeGO:00001651400.013
positive regulation of programmed cell deathGO:00430681570.013
cellular response to peptide hormone stimulusGO:00713751200.013
gamete generationGO:00072761240.013
positive regulation of immunoglobulin productionGO:000263940.013
cell motilityGO:00488702020.013
reactive nitrogen species metabolic processGO:200105710.013
monocarboxylic acid biosynthetic processGO:0072330480.013
immunoglobulin secretionGO:004830510.013
regulation of canonical wnt signaling pathwayGO:006082840.013
sex differentiationGO:00075481130.013
neural crest cell developmentGO:001403220.013
nucleoside metabolic processGO:00091161790.013
rhythmic processGO:00485111560.013
response to carbohydrateGO:00097431830.013
axon developmentGO:0061564960.013
regulation of immunoglobulin productionGO:000263740.013
positive regulation of protein modification processGO:00314011420.013
organophosphate catabolic processGO:00464341480.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
nucleoside triphosphate metabolic processGO:00091411440.013
establishment of protein localizationGO:00451841410.013
regulation of anatomical structure sizeGO:00900661350.013
axis specificationGO:000979840.013
negative regulation of neurogenesisGO:0050768780.013
tube developmentGO:0035295890.013
sodium ion transmembrane transportGO:0035725670.013
muscle contractionGO:0006936880.013
eye morphogenesisGO:004859240.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
single organism intracellular transportGO:19025821660.013
positive regulation of transferase activityGO:0051347810.013
neuron projection morphogenesisGO:00488121220.013
cell morphogenesis involved in neuron differentiationGO:00486671060.013
response to oxidative stressGO:00069791860.013
negative regulation of innate immune responseGO:004582440.013
fatty acid metabolic processGO:0006631990.013
negative regulation of cell differentiationGO:0045596990.013
circulatory system processGO:00030131830.013
signal transduction by phosphorylationGO:00230141440.013
cellular macromolecule localizationGO:00707271220.013
reactive oxygen species biosynthetic processGO:190340980.013
response to toxic substanceGO:00096361330.013
regulation of calcium ion transportGO:0051924770.013
monoamine transportGO:0015844430.013
cellular response to abiotic stimulusGO:0071214850.012
positive regulation of neuron differentiationGO:00456661260.012
cellular nitrogen compound catabolic processGO:00442701630.012
mechanoreceptor differentiationGO:004249020.012
developmental growthGO:00485891000.012
purine ribonucleotide metabolic processGO:00091502270.012
heart developmentGO:0007507720.012
cellular response to glucocorticoid stimulusGO:0071385680.012
circadian rhythmGO:0007623880.012
lipid metabolic processGO:00066292830.012
purine containing compound biosynthetic processGO:0072522850.012
positive regulation of rna biosynthetic processGO:19026801970.012
carbohydrate derivative biosynthetic processGO:19011371240.012
immune responseGO:00069551040.012
regulation of blood pressureGO:0008217830.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
cellular protein localizationGO:00346131220.012
organelle organizationGO:00069962660.012
hormone transportGO:00099141210.012
negative regulation of cellular biosynthetic processGO:00313271610.012
regulation of protein kinase activityGO:00458591050.012
cell part morphogenesisGO:00329901230.012
carboxylic acid catabolic processGO:0046395490.012
anterior posterior pattern specificationGO:000995210.012
single organism carbohydrate metabolic processGO:00447231180.012
positive regulation of secretion by cellGO:19035321280.012
peptidyl amino acid modificationGO:00181931260.012
positive regulation of apoptotic processGO:00430651540.012
response to radiationGO:00093141370.012
amide transportGO:00428861050.012
cytoplasmic transportGO:00164821150.012
regulation of proteasomal protein catabolic processGO:006113640.012
regulation of reactive oxygen species metabolic processGO:2000377260.012
regulation of neuron deathGO:19012141150.012
negative regulation of phosphate metabolic processGO:0045936800.012
response to glucoseGO:00097491360.012
negative regulation of phosphorus metabolic processGO:0010563800.011
negative regulation of nervous system developmentGO:0051961790.011
cytoskeleton dependent cytokinesisGO:006164020.011
purine ribonucleoside catabolic processGO:00461301240.011
response to vitamin b6GO:003451610.011
regulation of tube sizeGO:0035150890.011
glycosyl compound metabolic processGO:19016571820.011
cellular modified amino acid metabolic processGO:0006575610.011
gastrulationGO:000736920.011
heterocycle catabolic processGO:00467001670.011
ribonucleotide metabolic processGO:00092592310.011
hormone metabolic processGO:0042445690.011
nucleoside phosphate biosynthetic processGO:19012931020.011
embryonic pattern specificationGO:000988010.011
response to testosteroneGO:0033574550.011
regulation of response to stressGO:00801341260.011
calcium ion transportGO:00068161310.011
astrocyte activationGO:004814340.011
extracellular matrix constituent secretionGO:007027840.011
muscle tissue developmentGO:0060537580.011
regulation of locomotionGO:00400121480.011
regulation of lipid metabolic processGO:0019216680.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
positive regulation of transcription dna templatedGO:00458931970.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
purine nucleoside metabolic processGO:00422781690.011
cell adhesionGO:00071551100.011
cellular response to mechanical stimulusGO:0071260480.011
renal system processGO:0003014400.011
response to corticosteroneGO:0051412400.011
potassium ion transportGO:0006813970.011
negative regulation of transportGO:00510511360.011
catenin import into nucleusGO:003541110.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
carbohydrate derivative catabolic processGO:19011361470.011
adult locomotory behaviorGO:000834440.011
purine nucleotide catabolic processGO:00061951360.011
negative regulation of osteoblast differentiationGO:004566820.011
axonogenesisGO:0007409710.011
cellular response to alcoholGO:0097306870.011
development of primary sexual characteristicsGO:00451371070.011
regulation of transferase activityGO:00513381230.011
appendage morphogenesisGO:003510740.011
negative regulation of canonical wnt signaling pathwayGO:009009040.011
calcium ion homeostasisGO:00550741620.011
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.010
nucleoside catabolic processGO:00091641260.010
regulation of cell morphogenesisGO:0022604770.010
action potentialGO:0001508540.010
cellular divalent inorganic cation homeostasisGO:00725031620.010
organic acid catabolic processGO:0016054490.010
ribonucleoside catabolic processGO:00424541260.010
regulation of mapk cascadeGO:00434081160.010
cell cycle checkpointGO:000007520.010
response to axon injuryGO:0048678590.010
positive regulation of ion transportGO:0043270940.010
positive regulation of nucleotide metabolic processGO:0045981910.010
protein homooligomerizationGO:0051260910.010
ribonucleotide catabolic processGO:00092611360.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
nucleobase containing compound catabolic processGO:00346551520.010

Lcat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.030
Human
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.027
musculoskeletal system diseaseDOID:1700.021
inherited metabolic disorderDOID:65500.019
Human
vascular diseaseDOID:17800.018
cardiovascular system diseaseDOID:128700.018
muscle tissue diseaseDOID:6600.017
myopathyDOID:42300.017
muscular diseaseDOID:008000000.017
central nervous system diseaseDOID:33100.012
sensory system diseaseDOID:005015500.011