Rattus norvegicus

139 known processes

Abcb1a

ATP-binding cassette, sub-family B (MDR/TAP), member 1A

(Aliases: Abcb1,Mdr1a)

Abcb1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to extracellular stimulusGO:00099913800.117
response to nutrientGO:00075842480.101
response to nutrient levelsGO:00316673700.095
cellular response to oxygen containing compoundGO:19017013860.092
organic acid metabolic processGO:00060822920.090
response to corticosteroidGO:00319602350.085
positive regulation of signalingGO:00230562700.083
regulation of cellular component organizationGO:00511283680.080
response to toxic substanceGO:00096361330.078
response to estrogenGO:00436272320.077
intracellular signal transductionGO:00355563140.072
response to inorganic substanceGO:00100353770.071
neurological system processGO:00508772190.071
single organism reproductive processGO:00447022970.070
anatomical structure morphogenesisGO:00096532980.069
regulation of signal transductionGO:00099663180.064
single organism biosynthetic processGO:00447113420.064
positive regulation of nitrogen compound metabolic processGO:00511733340.062
positive regulation of developmental processGO:00510942830.061
positive regulation of multicellular organismal processGO:00512403870.060
cellular response to organic cyclic compoundGO:00714072020.059
regulation of multicellular organismal developmentGO:20000263760.059
response to woundingGO:00096112540.059
carboxylic acid metabolic processGO:00197522890.059
cellular response to organonitrogen compoundGO:00714171970.058
regulation of phosphate metabolic processGO:00192203490.058
regulation of nucleic acid templated transcriptionGO:19035063800.058
regulation of intracellular signal transductionGO:19025312180.058
positive regulation of cell communicationGO:00106472710.057
homeostatic processGO:00425923310.056
oxoacid metabolic processGO:00434362900.054
cation transportGO:00068123820.053
central nervous system developmentGO:00074173110.053
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.052
positive regulation of response to stimulusGO:00485842850.052
reproductive processGO:00224143720.050
transcription dna templatedGO:00063513770.050
response to vitaminGO:00332731310.049
response to peptideGO:19016522920.048
lipid metabolic processGO:00066292830.048
regulation of molecular functionGO:00650093980.048
regulation of catalytic activityGO:00507903040.045
regulation of phosphorus metabolic processGO:00511743490.045
cellular lipid metabolic processGO:00442552080.044
catabolic processGO:00090563510.044
Fly
head developmentGO:00603222470.044
rna metabolic processGO:00160704060.043
cellular catabolic processGO:00442482950.043
Fly
chemical homeostasisGO:00488782920.042
response to glucocorticoidGO:00513842230.042
inflammatory responseGO:00069541500.042
regulation of hormone levelsGO:00108171870.042
regulation of rna metabolic processGO:00512523910.042
positive regulation of signal transductionGO:00099671750.042
rna biosynthetic processGO:00327743800.042
regulation of cell proliferationGO:00421273590.041
apoptotic processGO:00069153810.041
organic substance catabolic processGO:19015753160.041
Fly
defense responseGO:00069521940.040
nucleic acid templated transcriptionGO:00976593790.040
cellular component movementGO:00069282480.040
Fly
positive regulation of catalytic activityGO:00430851840.040
regulation of cell differentiationGO:00455953200.040
brain developmentGO:00074202470.039
organophosphate metabolic processGO:00196373700.039
Fly
positive regulation of phosphate metabolic processGO:00459372620.039
regulation of cellular protein metabolic processGO:00322682670.039
transmembrane transportGO:00550854120.039
regulation of programmed cell deathGO:00430673410.039
oxidation reduction processGO:00551143040.039
cellular response to endogenous stimulusGO:00714953770.039
cellular component biogenesisGO:00440853680.038
response to ketoneGO:19016541820.038
regulation of protein metabolic processGO:00512462890.038
protein phosphorylationGO:00064683450.037
tissue developmentGO:00098882520.037
Rat
cellular amino acid metabolic processGO:00065201070.037
positive regulation of apoptotic processGO:00430651540.037
wound healingGO:00420601220.037
response to metal ionGO:00100382530.036
regulation of transcription dna templatedGO:00063553740.036
small molecule biosynthetic processGO:00442831240.036
multicellular organism reproductionGO:00325042330.035
Fly
reproductionGO:00000032450.035
Fly
multicellular organismal reproductive processGO:00486092330.034
Fly
response to decreased oxygen levelsGO:00362932370.034
positive regulation of phosphorus metabolic processGO:00105622620.034
positive regulation of phosphorylationGO:00423271770.034
positive regulation of biosynthetic processGO:00098913190.034
ion homeostasisGO:00508012120.033
regulation of rna biosynthetic processGO:20011413810.033
negative regulation of metabolic processGO:00098923310.033
cellular response to stressGO:00335542690.033
negative regulation of nitrogen compound metabolic processGO:00511721610.032
hormone metabolic processGO:0042445690.032
ion transmembrane transportGO:00342203650.032
amine metabolic processGO:0009308380.032
cellular homeostasisGO:00197252520.032
positive regulation of molecular functionGO:00440932300.032
immune system processGO:00023762040.031
nitrogen compound transportGO:00717052290.031
protein complex biogenesisGO:00702712630.031
negative regulation of cellular metabolic processGO:00313242810.031
renal system developmentGO:0072001670.031
mapk cascadeGO:00001651400.031
cation homeostasisGO:00550801950.031
heterocycle catabolic processGO:00467001670.030
Fly
response to hypoxiaGO:00016662310.030
purine containing compound metabolic processGO:00725212530.030
Fly
regulation of cellular localizationGO:00603412630.030
positive regulation of cellular protein metabolic processGO:00322701670.030
locomotionGO:00400112370.030
Fly
positive regulation of programmed cell deathGO:00430681570.030
metal ion transportGO:00300012890.030
cation transmembrane transportGO:00986552630.029
heart morphogenesisGO:000300730.029
response to acid chemicalGO:00011012220.029
response to peptide hormoneGO:00434342780.029
regulation of apoptotic processGO:00429813350.029
regulation of phosphorylationGO:00423252480.029
alpha amino acid metabolic processGO:1901605710.029
transcription from rna polymerase ii promoterGO:00063662520.029
regenerationGO:00310991630.029
cellular component assemblyGO:00226073600.029
positive regulation of cell deathGO:00109421840.029
blood circulationGO:00080151830.029
circulatory system processGO:00030131830.029
cellular ketone metabolic processGO:0042180510.028
cellular ion homeostasisGO:00068731840.028
calcium ion homeostasisGO:00550741620.028
negative regulation of macromolecule metabolic processGO:00106052600.028
neuron differentiationGO:00301823680.028
positive regulation of cellular biosynthetic processGO:00313282950.028
neuron developmentGO:00486662860.028
cellular metal ion homeostasisGO:00068751720.028
cellular chemical homeostasisGO:00550822470.028
negative regulation of molecular functionGO:00440921330.027
regulation of system processGO:00440572080.027
response to purine containing compoundGO:00140741260.027
response to oxygen levelsGO:00704822650.027
regulation of mapk cascadeGO:00434081160.027
g protein coupled receptor signaling pathwayGO:00071862420.027
positive regulation of gene expressionGO:00106282440.027
growthGO:00400071650.026
regulation of transcription from rna polymerase ii promoterGO:00063572340.026
single organism catabolic processGO:00447122830.026
Fly
anion transportGO:00068201780.026
regulation of cell growthGO:0001558850.026
cellular response to hormone stimulusGO:00328702470.026
nucleobase containing small molecule metabolic processGO:00550863160.026
Fly
positive regulation of protein modification processGO:00314011420.026
tube developmentGO:0035295890.026
negative regulation of transcription dna templatedGO:00458921160.026
lipid biosynthetic processGO:00086101280.025
nucleotide metabolic processGO:00091172790.025
Fly
cellular response to lipidGO:00713962010.025
cell migrationGO:00164771970.025
Fly
carbohydrate derivative metabolic processGO:19011353460.025
Fly
cellular cation homeostasisGO:00300031800.025
agingGO:00075682410.025
synaptic transmissionGO:00072682350.024
proteolysisGO:00065081750.024
macromolecular complex assemblyGO:00650032730.024
response to growth factorGO:00708481890.024
nucleobase containing compound catabolic processGO:00346551520.024
Fly
neuron projection developmentGO:00311752730.024
organic cyclic compound catabolic processGO:19013611750.024
Fly
programmed cell deathGO:00125013920.024
small molecule catabolic processGO:0044282590.024
secretion by cellGO:00329402480.024
cellular amine metabolic processGO:0044106380.024
monovalent inorganic cation transportGO:00156721720.024
response to vitamin dGO:0033280340.023
response to estradiolGO:00323551640.023
regulation of protein modification processGO:00313991940.023
response to alkaloidGO:00432791320.023
cellular divalent inorganic cation homeostasisGO:00725031620.023
positive regulation of intracellular signal transductionGO:19025331380.023
response to other organismGO:00517072200.023
protein oligomerizationGO:00512591910.023
protein complex subunit organizationGO:00718223020.023
regulation of blood pressureGO:0008217830.023
cell projection organizationGO:00300303020.023
positive regulation of cell proliferationGO:00082842490.022
macromolecule localizationGO:00330362520.022
cellular calcium ion homeostasisGO:00068741600.022
positive regulation of macromolecule biosynthetic processGO:00105572470.022
regulation of cellular ketone metabolic processGO:0010565270.022
regulation of nervous system developmentGO:00519602640.022
cellular component morphogenesisGO:00329891550.022
sexual reproductionGO:00199531480.022
Fly
divalent inorganic cation homeostasisGO:00725071650.022
purine ribonucleotide metabolic processGO:00091502270.022
Fly
gastrulationGO:000736920.022
macromolecular complex subunit organizationGO:00439333390.022
developmental growthGO:00485891000.022
negative regulation of cellular biosynthetic processGO:00313271610.022
protein complex assemblyGO:00064612630.021
regulation of cell developmentGO:00602842630.021
cellular response to peptideGO:19016531330.021
aromatic compound catabolic processGO:00194391680.021
Fly
regulation of anatomical structure morphogenesisGO:00226031410.021
response to cytokineGO:00340972150.021
Rat
negative regulation of macromolecule biosynthetic processGO:00105581480.021
action potentialGO:0001508540.021
cardiac ventricle developmentGO:000323110.020
regulation of membrane potentialGO:00423911100.020
negative regulation of cell differentiationGO:0045596990.020
negative regulation of cell deathGO:00605482290.020
negative regulation of programmed cell deathGO:00430691830.020
negative regulation of apoptotic processGO:00430661810.020
regulation of neurogenesisGO:00507672470.020
cell growthGO:00160491040.020
positive regulation of transcription dna templatedGO:00458931970.020
positive regulation of rna metabolic processGO:00512542030.020
regulation of fat cell differentiationGO:004559830.020
negative regulation of gene expressionGO:00106291990.020
positive regulation of cellular component organizationGO:00511302000.020
reproductive system developmentGO:00614581280.020
negative regulation of cell communicationGO:00106481580.020
ribonucleoside metabolic processGO:00091191740.020
Fly
regulation of cellular amino acid metabolic processGO:000652120.020
kidney developmentGO:0001822670.020
organonitrogen compound catabolic processGO:19015651790.020
Fly
ribose phosphate metabolic processGO:00196932350.019
Fly
cell type specific apoptotic processGO:00972851340.019
cellular response to nitrogen compoundGO:19016992100.019
intracellular transportGO:00469071850.019
regulation of cellular amine metabolic processGO:003323880.019
negative regulation of multicellular organismal processGO:00512412030.019
monocarboxylic acid metabolic processGO:00327871520.019
metal ion homeostasisGO:00550651860.019
gland developmentGO:00487321550.019
inorganic cation transmembrane transportGO:00986622020.019
nucleoside phosphate metabolic processGO:00067532830.019
Fly
response to oxidative stressGO:00069791860.019
positive regulation of nucleic acid templated transcriptionGO:19035081970.019
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.019
organelle organizationGO:00069962660.019
cardiovascular system developmentGO:00723581340.019
purine nucleotide metabolic processGO:00061632290.019
Fly
negative regulation of nucleobase containing compound metabolic processGO:00459341530.019
positive regulation of rna biosynthetic processGO:19026801970.019
regulation of homeostatic processGO:00328441010.019
negative regulation of transportGO:00510511360.018
reproductive structure developmentGO:00486081280.018
rhythmic processGO:00485111560.018
transmission of nerve impulseGO:0019226420.018
positive regulation of protein phosphorylationGO:00019341350.018
gonad developmentGO:00084061040.018
neuronal action potentialGO:0019228350.018
negative regulation of biosynthetic processGO:00098901680.018
liver developmentGO:0001889900.018
muscle system processGO:00030121150.018
carboxylic acid biosynthetic processGO:0046394830.018
negative regulation of cell proliferationGO:00082851190.018
negative regulation of developmental processGO:00510931250.018
multi organism reproductive processGO:00447032620.018
Fly
fatty acid metabolic processGO:0006631990.018
carboxylic acid transportGO:00469421150.018
cellular response to corticosteroid stimulusGO:0071384690.018
response to lipopolysaccharideGO:00324961910.018
organ morphogenesisGO:0009887750.017
hormone transportGO:00099141210.017
cardiac chamber developmentGO:000320510.017
organic acid transportGO:00158491160.017
cellular hormone metabolic processGO:0034754490.017
response to transition metal nanoparticleGO:19902671220.017
regulation of protein phosphorylationGO:00019321830.017
sulfur compound metabolic processGO:0006790700.017
cellular response to growth factor stimulusGO:00713631620.017
regulation of neuron differentiationGO:00456642080.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
cell projection morphogenesisGO:00488581230.017
cellular nitrogen compound catabolic processGO:00442701630.017
Fly
cellular response to peptide hormone stimulusGO:00713751200.017
protein heterooligomerizationGO:0051291890.017
purine nucleoside triphosphate catabolic processGO:00091461220.017
Fly
response to mechanical stimulusGO:00096121340.017
sensory organ developmentGO:0007423740.017
regulation of secretion by cellGO:19035302080.017
cell cell signalingGO:00072673350.017
steroid metabolic processGO:0008202730.017
response to campGO:0051591910.017
response to hexoseGO:00097461440.017
response to ethanolGO:00454711620.017
protein localizationGO:00081041910.017
gliogenesisGO:0042063930.016
Fly
secretionGO:00469033070.016
cellular modified amino acid metabolic processGO:0006575610.016
regulation of lipid metabolic processGO:0019216680.016
appendage morphogenesisGO:003510740.016
positive regulation of cell differentiationGO:00455972170.016
response to external biotic stimulusGO:00432072210.016
regulation of blood circulationGO:19035221100.016
behaviorGO:00076102050.016
organic anion transportGO:00157111320.016
multicellular organismal homeostasisGO:0048871490.016
circulatory system developmentGO:00723591340.016
regulation of response to stressGO:00801341260.016
response to molecule of bacterial originGO:00022371940.016
cell morphogenesisGO:00009021420.016
positive regulation of mapk cascadeGO:0043410920.016
organic hydroxy compound metabolic processGO:19016151150.016
hepaticobiliary system developmentGO:0061008900.016
multicellular organism growthGO:003526410.016
regulation of ion transportGO:00432692450.015
signal transduction by phosphorylationGO:00230141440.015
glycosyl compound metabolic processGO:19016571820.015
Fly
cell activationGO:0001775970.015
positive regulation of nucleotide metabolic processGO:0045981910.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
small gtpase mediated signal transductionGO:0007264360.015
forebrain developmentGO:0030900980.015
cell morphogenesis involved in differentiationGO:00009041190.015
nucleoside metabolic processGO:00091161790.015
Fly
biological adhesionGO:00226101100.015
regulation of kinase activityGO:00435491170.015
ras protein signal transductionGO:0007265290.015
eye morphogenesisGO:004859240.015
anterior posterior pattern specificationGO:000995210.015
negative regulation of rna metabolic processGO:00512531230.015
negative regulation of signalingGO:00230571570.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
developmental process involved in reproductionGO:00030061590.015
negative regulation of protein metabolic processGO:00512481140.015
cellular response to alcoholGO:0097306870.014
localization of cellGO:00516742020.014
Fly
organic hydroxy compound transportGO:0015850770.014
acute inflammatory responseGO:0002526580.014
embryonic skeletal system morphogenesisGO:004870430.014
organ regenerationGO:00311001010.014
smooth muscle cell proliferationGO:0048659770.014
cell cycleGO:00070491010.014
Human
organic acid biosynthetic processGO:0016053830.014
response to carbohydrateGO:00097431830.014
purine ribonucleoside metabolic processGO:00461281680.014
Fly
muscle cell proliferationGO:0033002840.014
single organism intracellular transportGO:19025821660.014
regulation of synaptic transmissionGO:00508041410.014
positive regulation of protein metabolic processGO:00512471780.014
urogenital system developmentGO:0001655780.014
positive regulation of transportGO:00510502450.014
telencephalon developmentGO:0021537620.014
regulation of transferase activityGO:00513381230.014
response to bacteriumGO:00096172000.014
inorganic ion transmembrane transportGO:00986602290.014
glial cell differentiationGO:0010001650.014
Fly
peptide biosynthetic processGO:004304330.014
bmp signaling pathwayGO:003050940.014
embryonic skeletal system developmentGO:004870630.014
positive regulation of transferase activityGO:0051347810.013
positive regulation of cell developmentGO:00107201760.013
negative regulation of rna biosynthetic processGO:19026791180.013
maintenance of locationGO:0051235170.013
cellular response to external stimulusGO:00714961180.013
response to glucoseGO:00097491360.013
establishment of protein localizationGO:00451841410.013
nucleoside phosphate catabolic processGO:19012921400.013
Fly
multi multicellular organism processGO:00447061380.013
cell motilityGO:00488702020.013
Fly
chemosensory behaviorGO:000763520.013
negative regulation of response to stimulusGO:00485851550.013
organonitrogen compound biosynthetic processGO:19015661670.013
organophosphate biosynthetic processGO:00904071430.013
neural crest cell differentiationGO:001403320.013
response to radiationGO:00093141370.013
Rat
positive regulation of cellular amino acid metabolic processGO:004576410.013
positive regulation of nervous system developmentGO:00519621780.013
cellular response to cytokine stimulusGO:00713451270.013
Rat
development of primary sexual characteristicsGO:00451371070.013
cell adhesionGO:00071551100.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
Fly
positive regulation of secretion by cellGO:19035321280.013
cellular response to glucocorticoid stimulusGO:0071385680.013
myelinationGO:0042552390.013
neural crest cell developmentGO:001403220.013
ribonucleotide metabolic processGO:00092592310.013
Fly
axon developmentGO:0061564960.012
dna metabolic processGO:0006259960.012
nucleoside triphosphate metabolic processGO:00091411440.012
Fly
mesoderm developmentGO:000749820.012
reactive oxygen species metabolic processGO:0072593370.012
purine ribonucleotide catabolic processGO:00091541360.012
Fly
cytosolic calcium ion homeostasisGO:00514801400.012
single organism behaviorGO:00447081300.012
regulation of growthGO:00400081050.012
lipid storageGO:001991510.012
amino acid transportGO:0006865700.012
ribonucleoside catabolic processGO:00424541260.012
Fly
regulation of protein localizationGO:0032880810.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
feeding behaviorGO:0007631530.012
negative regulation of cellular protein metabolic processGO:00322691060.012
purine nucleoside metabolic processGO:00422781690.012
Fly
multicellular organismal signalingGO:0035637440.012
purine nucleoside catabolic processGO:00061521240.012
Fly
cellular response to steroid hormone stimulusGO:0071383930.012
camera type eye developmentGO:0043010480.012
response to retinoic acidGO:0032526630.012
positive regulation of cellular amine metabolic processGO:003324030.012
response to organophosphorusGO:00466831020.012
regulation of cell migrationGO:00303341280.011
ribonucleotide catabolic processGO:00092611360.011
Fly
negative regulation of phosphate metabolic processGO:0045936800.011
positive regulation of neurogenesisGO:00507691650.011
negative regulation of catalytic activityGO:00430861030.011
gamete generationGO:00072761240.011
Fly
regulation of immune system processGO:00026821230.011
regulation of secretionGO:00510462240.011
purine nucleotide catabolic processGO:00061951360.011
Fly
axis specificationGO:000979840.011
regulation of purine nucleotide metabolic processGO:19005421150.011
response to antibioticGO:0046677390.011
positive regulation of immunoglobulin productionGO:000263940.011
carbohydrate derivative catabolic processGO:19011361470.011
Fly
epithelial cell differentiationGO:0030855710.011
Rat
skeletal system developmentGO:0001501410.011
odontogenesisGO:0042476320.011
dephosphorylationGO:0016311980.011
positive regulation of immune system processGO:0002684900.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
Fly
cellular protein localizationGO:00346131220.011
fatty acid oxidationGO:0019395290.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
cytoplasmic transportGO:00164821150.011
amide transportGO:00428861050.011
regulation of protein kinase activityGO:00458591050.011
mesenchymal cell proliferationGO:001046340.011
signal releaseGO:00230611450.011
neurotransmitter gated ion channel clusteringGO:007257830.011
calcium ion transportGO:00068161310.011
purine ribonucleoside catabolic processGO:00461301240.011
Fly
sex differentiationGO:00075481130.011
protein maturationGO:0051604680.011
divalent inorganic cation transportGO:00725111340.011
blood vessel developmentGO:0001568690.011
regulation of neuron projection developmentGO:00109751610.011
immune responseGO:00069551040.011
positive regulation of kinase activityGO:0033674770.010
nucleotide catabolic processGO:00091661390.010
Fly
lauric acid metabolic processGO:004825240.010
cellular response to abiotic stimulusGO:0071214850.010
regulation of canonical wnt signaling pathwayGO:006082840.010
organic acid catabolic processGO:0016054490.010
axon ensheathmentGO:0008366400.010
positive regulation of isotype switchingGO:004583010.010
regulation of hydrolase activityGO:00513361430.010
lipid oxidationGO:0034440300.010
embryonic appendage morphogenesisGO:003511340.010
positive regulation of ion transportGO:0043270940.010
regulation of intracellular transportGO:0032386650.010
terpenoid metabolic processGO:0006721370.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
connective tissue developmentGO:0061448330.010
regulation of response to external stimulusGO:00321011060.010

Abcb1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.023
disease of anatomical entityDOID:700.023
Human
musculoskeletal system diseaseDOID:1700.016
disease of metabolismDOID:001466700.015
inherited metabolic disorderDOID:65500.014
central nervous system diseaseDOID:33100.012