Rattus norvegicus

57 known processes

Hsd17b1

hydroxysteroid (17-beta) dehydrogenase 1

(Aliases: 17BHD1)

Hsd17b1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell proliferationGO:00421273590.308
head developmentGO:00603222470.269
immune system processGO:00023762040.256
response to nutrient levelsGO:00316673700.220
brain developmentGO:00074202470.217
response to inorganic substanceGO:00100353770.201
cellular chemical homeostasisGO:00550822470.180
cellular response to organonitrogen compoundGO:00714171970.157
regulation of calcium ion transportGO:0051924770.156
regulation of secretionGO:00510462240.143
cation transportGO:00068123820.127
divalent inorganic cation transportGO:00725111340.126
response to glucocorticoidGO:00513842230.124
agingGO:00075682410.118
positive regulation of transportGO:00510502450.115
positive regulation of secretionGO:00510471400.113
cellular response to oxygen containing compoundGO:19017013860.113
positive regulation of rna biosynthetic processGO:19026801970.110
rna metabolic processGO:00160704060.109
response to metal ionGO:00100382530.109
macromolecule localizationGO:00330362520.109
metal ion transportGO:00300012890.106
positive regulation of biosynthetic processGO:00098913190.106
cellular response to organic cyclic compoundGO:00714072020.105
lipid biosynthetic processGO:00086101280.104
response to nutrientGO:00075842480.103
response to organophosphorusGO:00466831020.100
response to corticosteroidGO:00319602350.098
cellular response to lipidGO:00713962010.097
divalent metal ion transportGO:00708381320.095
negative regulation of gene expressionGO:00106291990.093
regulation of peptide transportGO:0090087870.089
cellular homeostasisGO:00197252520.087
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.086
vesicle mediated transportGO:00161921810.084
response to extracellular stimulusGO:00099913800.081
forebrain developmentGO:0030900980.079
positive regulation of cell proliferationGO:00082842490.076
transcription dna templatedGO:00063513770.075
nucleic acid templated transcriptionGO:00976593790.075
monocarboxylic acid transportGO:0015718520.074
cellular response to nitrogen compoundGO:19016992100.073
negative regulation of metabolic processGO:00098923310.073
response to peptide hormoneGO:00434342780.073
regulation of rna metabolic processGO:00512523910.073
response to purine containing compoundGO:00140741260.073
regulation of metal ion transportGO:00109591180.073
positive regulation of immune responseGO:0050778420.072
single organism biosynthetic processGO:00447113420.071
muscle cell proliferationGO:0033002840.070
response to monosaccharideGO:00342841590.068
central nervous system developmentGO:00074173110.067
secretion by cellGO:00329402480.067
programmed cell deathGO:00125013920.066
response to hexoseGO:00097461440.065
regulation of rna biosynthetic processGO:20011413810.065
response to estrogenGO:00436272320.064
response to peptideGO:19016522920.062
intracellular transportGO:00469071850.061
secretionGO:00469033070.060
regulation of cellular localizationGO:00603412630.060
cellular response to cytokine stimulusGO:00713451270.059
chemical homeostasisGO:00488782920.059
defense responseGO:00069521940.058
positive regulation of ion transportGO:0043270940.058
response to mineralocorticoidGO:0051385490.055
response to glucoseGO:00097491360.055
regulation of intracellular signal transductionGO:19025312180.055
regulation of cellular component organizationGO:00511283680.055
organophosphate metabolic processGO:00196373700.055
positive regulation of secretion by cellGO:19035321280.055
response to other organismGO:00517072200.052
positive regulation of rna metabolic processGO:00512542030.052
positive regulation of cellular biosynthetic processGO:00313282950.051
cellular response to hexose stimulusGO:0071331650.051
negative regulation of macromolecule metabolic processGO:00106052600.051
transmembrane transportGO:00550854120.050
inflammatory responseGO:00069541500.050
positive regulation of nucleic acid templated transcriptionGO:19035081970.049
lipid metabolic processGO:00066292830.049
regulation of ion transportGO:00432692450.048
oxidation reduction processGO:00551143040.047
cellular response to steroid hormone stimulusGO:0071383930.046
response to vitaminGO:00332731310.046
response to carbohydrateGO:00097431830.046
positive regulation of cellular component organizationGO:00511302000.046
leukocyte activationGO:0045321760.046
negative regulation of multicellular organismal processGO:00512412030.045
regulation of secretion by cellGO:19035302080.045
glucose homeostasisGO:0042593750.044
regulation of transcription dna templatedGO:00063553740.044
homeostatic processGO:00425923310.044
cellular response to stressGO:00335542690.043
positive regulation of homeostatic processGO:0032846490.043
cellular response to alcoholGO:0097306870.042
epithelium developmentGO:0060429960.042
cell activationGO:0001775970.042
response to campGO:0051591910.042
organic substance catabolic processGO:19015753160.042
regulation of blood pressureGO:0008217830.040
regulation of response to external stimulusGO:00321011060.040
organic acid metabolic processGO:00060822920.039
regulation of nucleic acid templated transcriptionGO:19035063800.039
b cell differentiationGO:003018320.039
positive regulation of macromolecule biosynthetic processGO:00105572470.039
regulation of signal transductionGO:00099663180.039
regulation of catecholamine secretionGO:0050433320.039
negative regulation of biosynthetic processGO:00098901680.038
nitrogen compound transportGO:00717052290.038
rna biosynthetic processGO:00327743800.037
peptide secretionGO:0002790860.037
response to estradiolGO:00323551640.037
positive regulation of developmental processGO:00510942830.037
establishment of protein localization to organelleGO:0072594440.037
lymphocyte activationGO:0046649430.037
cellular response to interleukin 6GO:007135490.036
cellular metal ion homeostasisGO:00068751720.036
regulation of apoptotic processGO:00429813350.036
lymphoid progenitor cell differentiationGO:000232020.035
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.035
positive regulation of nitrogen compound metabolic processGO:00511733340.035
calcium ion transportGO:00068161310.035
regulation of anatomical structure morphogenesisGO:00226031410.035
ribose phosphate metabolic processGO:00196932350.034
negative regulation of nitrogen compound metabolic processGO:00511721610.034
oxoacid metabolic processGO:00434362900.034
locomotionGO:00400112370.034
regulation of catalytic activityGO:00507903040.034
reactive oxygen species metabolic processGO:0072593370.034
immune responseGO:00069551040.034
protein transportGO:00150311320.034
reactive nitrogen species metabolic processGO:200105710.034
carboxylic acid metabolic processGO:00197522890.034
positive regulation of calcium ion transportGO:0051928360.034
positive regulation of blood circulationGO:1903524650.033
negative regulation of cellular biosynthetic processGO:00313271610.033
carbohydrate homeostasisGO:0033500750.033
protein complex assemblyGO:00064612630.033
positive regulation of gene expressionGO:00106282440.032
protein heterooligomerizationGO:0051291890.032
negative regulation of nucleobase containing compound metabolic processGO:00459341530.032
response to oxygen levelsGO:00704822650.032
regulation of cell differentiationGO:00455953200.032
positive regulation of cellular amine metabolic processGO:003324030.032
g protein coupled receptor signaling pathwayGO:00071862420.032
positive regulation of cellular amino acid metabolic processGO:004576410.032
protein secretionGO:0009306340.031
regulation of adenylate cyclase activityGO:0045761180.031
calcium ion importGO:0070509220.031
protein complex subunit organizationGO:00718223020.031
response to molecule of bacterial originGO:00022371940.031
positive regulation of transcription dna templatedGO:00458931970.031
cellular amino acid metabolic processGO:00065201070.030
negative regulation of cellular metabolic processGO:00313242810.030
nucleotide metabolic processGO:00091172790.030
tonic smooth muscle contractionGO:001482040.030
regulation of molecular functionGO:00650093980.030
regulation of phosphate metabolic processGO:00192203490.029
cellular response to glucose stimulusGO:0071333650.029
response to calcium ionGO:0051592590.029
positive regulation of multicellular organismal processGO:00512403870.029
nuclear transportGO:0051169490.029
smooth muscle cell proliferationGO:0048659770.029
cellular response to glucocorticoid stimulusGO:0071385680.029
response to fatty acidGO:0070542650.028
single organism carbohydrate metabolic processGO:00447231180.028
regulation of multicellular organismal developmentGO:20000263760.028
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.028
alcohol metabolic processGO:0006066770.028
carbohydrate derivative metabolic processGO:19011353460.028
regulation of reactive oxygen species biosynthetic processGO:190342650.028
proteolysisGO:00065081750.028
response to biotic stimulusGO:00096072260.028
cellular ion homeostasisGO:00068731840.028
cell cell signalingGO:00072673350.027
response to alkaloidGO:00432791320.027
positive regulation of catalytic activityGO:00430851840.027
single organism intracellular transportGO:19025821660.027
alpha amino acid metabolic processGO:1901605710.027
regulation of cellular amine metabolic processGO:003323880.026
nucleoside phosphate biosynthetic processGO:19012931020.026
organic acid biosynthetic processGO:0016053830.026
regulation of hormone secretionGO:00468831060.026
regulation of synaptic plasticityGO:0048167700.026
protein oligomerizationGO:00512591910.026
response to hypoxiaGO:00016662310.026
establishment of protein localizationGO:00451841410.026
muscle structure developmentGO:0061061870.026
regulation of locomotionGO:00400121480.025
growthGO:00400071650.025
response to ethanolGO:00454711620.025
artery smooth muscle contractionGO:001482440.025
catecholamine transportGO:0051937370.025
organic acid transportGO:00158491160.025
ribonucleotide metabolic processGO:00092592310.025
urogenital system developmentGO:0001655780.025
cellular response to endogenous stimulusGO:00714953770.025
cellular carbohydrate metabolic processGO:0044262720.025
positive regulation of nucleotide biosynthetic processGO:0030810360.025
amine metabolic processGO:0009308380.025
response to acid chemicalGO:00011012220.025
behaviorGO:00076102050.025
regulation of transmembrane transportGO:00347621220.025
organic hydroxy compound transportGO:0015850770.025
nucleoside phosphate metabolic processGO:00067532830.024
regulation of peptide secretionGO:0002791820.024
cellular response to external stimulusGO:00714961180.024
carbohydrate metabolic processGO:00059751300.024
response to growth factorGO:00708481890.024
ribose phosphate biosynthetic processGO:0046390870.024
catecholamine secretionGO:0050432330.024
small molecule biosynthetic processGO:00442831240.024
regulation of programmed cell deathGO:00430673410.024
response to lead ionGO:0010288330.024
protein complex biogenesisGO:00702712630.024
cation homeostasisGO:00550801950.023
regulation of amine transportGO:0051952540.023
carbohydrate derivative biosynthetic processGO:19011371240.023
cytoplasmic transportGO:00164821150.023
response to toxic substanceGO:00096361330.023
cellular component biogenesisGO:00440853680.023
nucleoside metabolic processGO:00091161790.023
reactive oxygen species biosynthetic processGO:190340980.023
negative regulation of transcription dna templatedGO:00458921160.023
renal system processGO:0003014400.023
apoptotic processGO:00069153810.023
liver developmentGO:0001889900.022
negative regulation of macromolecule biosynthetic processGO:00105581480.022
negative regulation of rna metabolic processGO:00512531230.022
organ regenerationGO:00311001010.022
cellular response to growth factor stimulusGO:00713631620.022
cellular ketone metabolic processGO:0042180510.022
regulation of cell projection organizationGO:00313441750.022
regulation of peptide hormone secretionGO:0090276800.022
intracellular signal transductionGO:00355563140.022
monoamine transportGO:0015844430.022
cyclic purine nucleotide metabolic processGO:0052652620.022
regulation of cellular amino acid metabolic processGO:000652120.022
regulation of long term neuronal synaptic plasticityGO:0048169150.022
transcription from rna polymerase ii promoterGO:00063662520.021
positive regulation of programmed cell deathGO:00430681570.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
positive regulation of locomotionGO:00400171020.021
regulation of cellular ketone metabolic processGO:0010565270.021
negative regulation of molecular functionGO:00440921330.021
positive regulation of cell deathGO:00109421840.021
cell motilityGO:00488702020.021
purine ribonucleotide metabolic processGO:00091502270.021
small gtpase mediated signal transductionGO:0007264360.021
signal releaseGO:00230611450.020
positive regulation of phosphorus metabolic processGO:00105622620.020
ion homeostasisGO:00508012120.020
cellular amine metabolic processGO:0044106380.020
development of primary sexual characteristicsGO:00451371070.020
insulin secretionGO:0030073690.020
ion transmembrane transportGO:00342203650.020
carboxylic acid transportGO:00469421150.020
cytokine productionGO:0001816610.020
negative regulation of programmed cell deathGO:00430691830.020
carboxylic acid biosynthetic processGO:0046394830.020
regulation of immune responseGO:0050776550.020
amide transportGO:00428861050.020
renal system developmentGO:0072001670.020
nucleocytoplasmic transportGO:0006913480.020
neuron projection developmentGO:00311752730.020
multicellular organism growthGO:003526410.019
purine containing compound metabolic processGO:00725212530.019
purine nucleotide metabolic processGO:00061632290.019
cellular response to carbohydrate stimulusGO:0071322720.019
amino acid transportGO:0006865700.019
protein localization to organelleGO:0033365570.018
muscle tissue developmentGO:0060537580.018
positive regulation of cell developmentGO:00107201760.018
monovalent inorganic cation transportGO:00156721720.018
regulation of smooth muscle cell proliferationGO:0048660750.018
potassium ion transportGO:0006813970.018
negative regulation of cellular protein metabolic processGO:00322691060.018
regulation of neuron differentiationGO:00456642080.018
response to decreased oxygen levelsGO:00362932370.018
cellular glucose homeostasisGO:0001678660.018
regulation of cellular carbohydrate metabolic processGO:0010675390.018
respiratory system processGO:000301630.018
response to interleukin 1GO:0070555550.018
regulation of mesenchymal cell proliferationGO:001046440.018
regulation of transcription from rna polymerase ii promoterGO:00063572340.018
positive regulation of neuron differentiationGO:00456661260.018
negative regulation of rna biosynthetic processGO:19026791180.018
glycosyl compound metabolic processGO:19016571820.017
reproductive structure developmentGO:00486081280.017
response to cocaineGO:0042220390.017
cellular amino acid biosynthetic processGO:0008652320.017
cellular response to hormone stimulusGO:00328702470.017
interleukin 12 productionGO:003261530.017
hormone transportGO:00099141210.017
alpha amino acid biosynthetic processGO:1901607230.017
positive regulation of transferase activityGO:0051347810.017
multicellular organism reproductionGO:00325042330.017
divalent inorganic cation homeostasisGO:00725071650.017
norepinephrine transportGO:0015874180.017
female pregnancyGO:00075651220.017
regulation of cell activationGO:0050865500.017
cellular response to corticosteroid stimulusGO:0071384690.017
negative regulation of response to stimulusGO:00485851550.017
ribonucleotide biosynthetic processGO:0009260850.017
purine ribonucleoside metabolic processGO:00461281680.017
regulation of hydrolase activityGO:00513361430.017
organophosphate biosynthetic processGO:00904071430.017
mesenchymal cell proliferationGO:001046340.016
single organism organelle organizationGO:19025891800.016
gastrulationGO:000736920.016
glycogen metabolic processGO:0005977230.016
positive regulation of phosphorylationGO:00423271770.016
regulation of reactive oxygen species metabolic processGO:2000377260.016
defense response to other organismGO:0098542170.016
sensory perceptionGO:00076001010.016
multicellular organismal reproductive processGO:00486092330.016
positive regulation of response to stimulusGO:00485842850.016
desensitization of g protein coupled receptor protein signaling pathwayGO:0002029100.016
nucleobase containing small molecule metabolic processGO:00550863160.016
cellular response to monosaccharide stimulusGO:0071326670.016
negative regulation of response to external stimulusGO:0032102370.016
positive regulation of cell projection organizationGO:00313461110.016
regulation of neuron deathGO:19012141150.016
response to bacteriumGO:00096172000.016
reproductive processGO:00224143720.016
response to activityGO:0014823730.016
positive regulation of isotype switchingGO:004583010.015
negative regulation of secretion by cellGO:1903531720.015
stress activated protein kinase signaling cascadeGO:0031098370.015
protein localizationGO:00081041910.015
peptide transportGO:0015833970.015
embryonic skeletal system morphogenesisGO:004870430.015
palate developmentGO:006002120.015
positive regulation of cell differentiationGO:00455972170.015
response to corticosteroneGO:0051412400.015
response to lipopolysaccharideGO:00324961910.015
synaptic transmissionGO:00072682350.015
negative regulation of protein metabolic processGO:00512481140.015
localization of cellGO:00516742020.015
positive regulation of hydrolase activityGO:0051345860.015
regulation of neurogenesisGO:00507672470.015
nucleotide biosynthetic processGO:0009165980.015
metal ion homeostasisGO:00550651860.015
ribonucleotide catabolic processGO:00092611360.015
regulation of isotype switchingGO:004519110.015
regulation of camp biosynthetic processGO:0030817380.015
regulation of immunoglobulin productionGO:000263740.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
mononuclear cell proliferationGO:0032943290.015
regulation of cyclic nucleotide biosynthetic processGO:0030802450.015
negative regulation of signal transductionGO:0009968830.015
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.014
lipid transportGO:0006869610.014
positive regulation of cell communicationGO:00106472710.014
purine nucleoside metabolic processGO:00422781690.014
catenin import into nucleusGO:003541110.014
response to amineGO:0014075460.014
epithelial cell proliferationGO:0050673540.014
regulation of hormone levelsGO:00108171870.014
inorganic ion transmembrane transportGO:00986602290.014
cellular response to peptide hormone stimulusGO:00713751200.014
endocrine processGO:0050886320.014
response to ketoneGO:19016541820.014
positive regulation of intracellular signal transductionGO:19025331380.014
response to woundingGO:00096112540.014
cellular response to peptideGO:19016531330.014
positive regulation of signal transductionGO:00099671750.014
positive regulation of cellular protein metabolic processGO:00322701670.014
protein targetingGO:0006605610.014
regulation of protein metabolic processGO:00512462890.014
carbohydrate biosynthetic processGO:0016051420.014
cellular response to interleukin 1GO:0071347370.014
organonitrogen compound biosynthetic processGO:19015661670.014
catabolic processGO:00090563510.014
positive regulation of mesenchymal cell proliferationGO:000205340.014
cell projection organizationGO:00300303020.014
purine ribonucleotide biosynthetic processGO:0009152810.013
regulation of kinase activityGO:00435491170.013
positive regulation of nervous system developmentGO:00519621780.013
hormone secretionGO:00468791150.013
response to ammonium ionGO:0060359710.013
regulation of cell motilityGO:20001451310.013
anatomical structure homeostasisGO:0060249290.013
regulation of nervous system developmentGO:00519602640.013
reproductive system developmentGO:00614581280.013
organelle organizationGO:00069962660.013
protein homooligomerizationGO:0051260910.013
multicellular organismal homeostasisGO:0048871490.013
acid secretionGO:0046717480.013
cellular component assemblyGO:00226073600.013
sensory perception of light stimulusGO:005095330.013
regulation of extracellular matrix constituent secretionGO:000333020.013
negative regulation of response to woundingGO:1903035230.013
response to muscle activity involved in regulation of muscle adaptationGO:001487320.013
cell growthGO:00160491040.013
striated muscle tissue developmentGO:0014706580.013
positive regulation of signalingGO:00230562700.013
purine ribonucleoside monophosphate metabolic processGO:0009167840.013
energy reserve metabolic processGO:0006112250.013
excretionGO:0007588240.013
molting cycleGO:004230330.013
negative regulation of catalytic activityGO:00430861030.013
regulation of protein processingGO:0070613500.013
carbohydrate derivative catabolic processGO:19011361470.013
kidney developmentGO:0001822670.012
regulation of leukocyte activationGO:0002694450.012
positive regulation of immune system processGO:0002684900.012
negative regulation of smooth muscle contractionGO:004598670.012
monocarboxylic acid metabolic processGO:00327871520.012
regulation of lyase activityGO:0051339220.012
regulation of transferase activityGO:00513381230.012
telencephalon developmentGO:0021537620.012
negative regulation of secretionGO:0051048820.012
camp metabolic processGO:0046058630.012
purine ribonucleotide catabolic processGO:00091541360.012
regulation of cellular protein metabolic processGO:00322682670.012
regulation of exocytosisGO:0017157370.012
negative regulation of transportGO:00510511360.012
regulation of carbohydrate metabolic processGO:0006109410.012
sexual reproductionGO:00199531480.012
positive regulation of serotonin secretionGO:001406410.012
cellular polysaccharide metabolic processGO:0044264230.012
cellular nitrogen compound catabolic processGO:00442701630.012
regulation of system processGO:00440572080.012
positive regulation of protein metabolic processGO:00512471780.012
positive regulation of molecular functionGO:00440932300.012
regulation of phosphorylationGO:00423252480.012
energy derivation by oxidation of organic compoundsGO:0015980460.012
dorsal ventral axon guidanceGO:003356310.012
phospholipid biosynthetic processGO:0008654290.012
regulation of defense responseGO:0031347680.012
negative regulation of cell communicationGO:00106481580.012
regulation of insulin secretionGO:0050796650.012
cation transmembrane transportGO:00986552630.012
negative regulation of signalingGO:00230571570.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
steroid metabolic processGO:0008202730.011
response to amphetamineGO:0001975250.011
single organism catabolic processGO:00447122830.011
positive regulation of phosphate metabolic processGO:00459372620.011
cellular catabolic processGO:00442482950.011
cellular cation homeostasisGO:00300031800.011
cellular response to drugGO:0035690300.011
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.011
regenerationGO:00310991630.011
vasodilationGO:0042311440.011
positive regulation of insulin secretionGO:0032024360.011
organophosphate catabolic processGO:00464341480.011
regulation of response to woundingGO:1903034690.011
negative regulation of apoptotic processGO:00430661810.011
regulation of catabolic processGO:00098941130.011
lipid localizationGO:0010876620.011
ribonucleoside metabolic processGO:00091191740.011
signal transduction by phosphorylationGO:00230141440.011
cellular glucan metabolic processGO:0006073230.011
positive regulation of cell motilityGO:2000147970.011
camera type eye morphogenesisGO:004859320.011
amine transportGO:0015837570.011
regulation of ion homeostasisGO:2000021630.011
male gamete generationGO:0048232990.011
protein localization to nucleusGO:0034504390.011
cellular sodium ion homeostasisGO:000688340.011
positive regulation of camp biosynthetic processGO:0030819280.011
cellular protein localizationGO:00346131220.011
negative regulation of cell deathGO:00605482290.011
positive regulation of protein modification processGO:00314011420.011
cellular lipid metabolic processGO:00442552080.011
mitochondrion organizationGO:0007005350.011
multi organism reproductive processGO:00447032620.011
negative regulation of phosphate metabolic processGO:0045936800.011
cyclic nucleotide metabolic processGO:0009187800.011
negative regulation of neuron deathGO:1901215690.011
positive regulation of vasodilationGO:0045909290.011
negative regulation of cell proliferationGO:00082851190.011
norepinephrine secretionGO:0048243160.011
t cell activationGO:0042110290.011
salivary gland developmentGO:000743130.011
cellular response to oxidative stressGO:0034599760.011
dendrite developmentGO:0016358720.011
digestive system processGO:0022600240.011
neuron deathGO:00709971270.011
glucan metabolic processGO:0044042230.011
sex differentiationGO:00075481130.011
dna metabolic processGO:0006259960.011
hepaticobiliary system developmentGO:0061008900.010
regulation of body fluid levelsGO:0050878900.010
regulation of ion transmembrane transportGO:00347651210.010
macromolecular complex assemblyGO:00650032730.010
response to interferon gammaGO:0034341200.010

Hsd17b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
nervous system diseaseDOID:86300.024
urinary system diseaseDOID:1800.019
disease of metabolismDOID:001466700.019
musculoskeletal system diseaseDOID:1700.014
connective tissue diseaseDOID:6500.011