Rattus norvegicus

176 known processes

Rtn4

reticulon 4

(Aliases: rat NogoA,rat N,r,Vp20,NI-250,MGC116054)

Rtn4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of protein metabolic processGO:00512462890.385
regulation of molecular functionGO:00650093980.232
cellular macromolecule localizationGO:00707271220.216
cellular component morphogenesisGO:00329891550.202
cell projection morphogenesisGO:00488581230.184
carboxylic acid metabolic processGO:00197522890.164
regulation of phosphorus metabolic processGO:00511743490.158
protein phosphorylationGO:00064683450.155
negative regulation of metabolic processGO:00098923310.152
protein localizationGO:00081041910.146
neuron projection morphogenesisGO:00488121220.142
regulation of phosphate metabolic processGO:00192203490.136
protein transportGO:00150311320.121
cation transportGO:00068123820.116
neuron projection developmentGO:00311752730.113
circulatory system developmentGO:00723591340.111
cell morphogenesisGO:00009021420.109
regulation of protein modification processGO:00313991940.106
anatomical structure morphogenesisGO:00096532980.104
positive regulation of protein metabolic processGO:00512471780.104
cellular component biogenesisGO:00440853680.102
protein complex assemblyGO:00064612630.102
single organism cellular localizationGO:19025801020.099
establishment of protein localizationGO:00451841410.099
regulation of cellular protein metabolic processGO:00322682670.096
positive regulation of multicellular organismal processGO:00512403870.092
positive regulation of signalingGO:00230562700.092
positive regulation of cell projection organizationGO:00313461110.091
negative regulation of macromolecule metabolic processGO:00106052600.091
oxoacid metabolic processGO:00434362900.089
organic acid metabolic processGO:00060822920.089
positive regulation of cellular biosynthetic processGO:00313282950.089
negative regulation of transportGO:00510511360.087
cellular protein localizationGO:00346131220.086
chromosome segregationGO:000705920.085
cell projection organizationGO:00300303020.084
nucleoside triphosphate catabolic processGO:00091431230.081
protein dephosphorylationGO:0006470380.079
positive regulation of neurogenesisGO:00507691650.077
catabolic processGO:00090563510.077
macromolecular complex assemblyGO:00650032730.076
positive regulation of cell communicationGO:00106472710.076
positive regulation of nucleobase containing compound metabolic processGO:00459353190.073
regulation of signal transductionGO:00099663180.073
regulation of cell projection organizationGO:00313441750.072
organic substance catabolic processGO:19015753160.071
brain developmentGO:00074202470.070
ribonucleotide metabolic processGO:00092592310.070
regulation of protein phosphorylationGO:00019321830.070
cellular component assemblyGO:00226073600.070
vesicle mediated transportGO:00161921810.069
macromolecule localizationGO:00330362520.069
cell morphogenesis involved in neuron differentiationGO:00486671060.068
regulation of catalytic activityGO:00507903040.068
cellular response to stressGO:00335542690.067
programmed cell deathGO:00125013920.067
positive regulation of biosynthetic processGO:00098913190.067
positive regulation of developmental processGO:00510942830.066
positive regulation of phosphate metabolic processGO:00459372620.066
positive regulation of signal transductionGO:00099671750.063
localization of cellGO:00516742020.063
regulation of ion transportGO:00432692450.063
positive regulation of nitrogen compound metabolic processGO:00511733340.061
metal ion transportGO:00300012890.061
positive regulation of gene expressionGO:00106282440.061
regulation of rna biosynthetic processGO:20011413810.060
organophosphate metabolic processGO:00196373700.058
positive regulation of cell differentiationGO:00455972170.057
dendrite developmentGO:0016358720.057
purine nucleoside triphosphate metabolic processGO:00091441410.057
ribonucleoside metabolic processGO:00091191740.055
cellular response to endogenous stimulusGO:00714953770.055
nitrogen compound transportGO:00717052290.055
cardiovascular system developmentGO:00723581340.054
intracellular signal transductionGO:00355563140.053
rna biosynthetic processGO:00327743800.053
transcription dna templatedGO:00063513770.052
regulation of programmed cell deathGO:00430673410.052
regulation of nervous system developmentGO:00519602640.051
inorganic ion transmembrane transportGO:00986602290.051
intracellular transportGO:00469071850.050
amine metabolic processGO:0009308380.050
positive regulation of cellular component organizationGO:00511302000.050
nucleobase containing small molecule metabolic processGO:00550863160.050
regulation of cellular amine metabolic processGO:003323880.050
cation homeostasisGO:00550801950.049
positive regulation of cellular protein metabolic processGO:00322701670.049
ion transmembrane transportGO:00342203650.049
transcription from rna polymerase ii promoterGO:00063662520.049
regulation of cell differentiationGO:00455953200.048
macromolecular complex subunit organizationGO:00439333390.048
neuron developmentGO:00486662860.048
blood vessel developmentGO:0001568690.047
regulation of cellular ketone metabolic processGO:0010565270.047
cell migrationGO:00164771970.047
response to carbohydrateGO:00097431830.047
regulation of rna metabolic processGO:00512523910.046
positive regulation of macromolecule biosynthetic processGO:00105572470.046
glycosyl compound metabolic processGO:19016571820.045
positive regulation of neuron projection developmentGO:0010976990.045
regulation of nucleic acid templated transcriptionGO:19035063800.045
purine nucleotide metabolic processGO:00061632290.044
regulation of neuron projection developmentGO:00109751610.044
nucleoside phosphate metabolic processGO:00067532830.043
purine nucleoside triphosphate catabolic processGO:00091461220.043
proteolysisGO:00065081750.043
regulation of cellular localizationGO:00603412630.042
regulation of cellular component organizationGO:00511283680.042
head developmentGO:00603222470.042
purine containing compound metabolic processGO:00725212530.042
neuron differentiationGO:00301823680.041
single organism intracellular transportGO:19025821660.041
ion homeostasisGO:00508012120.041
purine ribonucleoside metabolic processGO:00461281680.041
positive regulation of phosphorus metabolic processGO:00105622620.040
homeostatic processGO:00425923310.040
cell motilityGO:00488702020.040
positive regulation of protein phosphorylationGO:00019341350.039
regulation of system processGO:00440572080.039
regulation of transcription dna templatedGO:00063553740.039
actin cytoskeleton organizationGO:0030036730.039
negative regulation of cellular metabolic processGO:00313242810.039
negative regulation of gene expressionGO:00106291990.039
metal ion homeostasisGO:00550651860.039
guanosine containing compound metabolic processGO:1901068740.038
positive regulation of molecular functionGO:00440932300.038
cellular homeostasisGO:00197252520.038
muscle contractionGO:0006936880.038
cell part morphogenesisGO:00329901230.037
cellular amine metabolic processGO:0044106380.037
cellular ketone metabolic processGO:0042180510.037
chemical homeostasisGO:00488782920.037
endomembrane system organizationGO:0010256480.036
regulation of cellular amino acid metabolic processGO:000652120.036
anterior posterior pattern specificationGO:000995210.036
embryonic pattern specificationGO:000988010.036
cellular component movementGO:00069282480.035
muscle system processGO:00030121150.035
cellular catabolic processGO:00442482950.035
secretion by cellGO:00329402480.035
positive regulation of response to stimulusGO:00485842850.035
organelle organizationGO:00069962660.035
organelle localizationGO:0051640550.035
positive regulation of transcription dna templatedGO:00458931970.035
carbohydrate derivative metabolic processGO:19011353460.034
protein complex biogenesisGO:00702712630.034
regulation of kinase activityGO:00435491170.034
positive regulation of nervous system developmentGO:00519621780.034
anatomical structure formation involved in morphogenesisGO:0048646830.034
regulation of cell developmentGO:00602842630.034
establishment of organelle localizationGO:0051656370.033
positive regulation of intracellular signal transductionGO:19025331380.033
blood vessel morphogenesisGO:0048514580.033
transmembrane transportGO:00550854120.033
cell growthGO:00160491040.032
ras protein signal transductionGO:0007265290.032
regulation of anatomical structure sizeGO:00900661350.032
cellular amino acid metabolic processGO:00065201070.032
cellular ion homeostasisGO:00068731840.032
dephosphorylationGO:0016311980.032
cytoplasmic transportGO:00164821150.032
secretionGO:00469033070.032
positive regulation of nucleic acid templated transcriptionGO:19035081970.031
nucleotide metabolic processGO:00091172790.031
reproductive processGO:00224143720.031
blood circulationGO:00080151830.031
protein localization to organelleGO:0033365570.031
regulation of g0 to g1 transitionGO:007031630.031
positive regulation of protein modification processGO:00314011420.031
gtp catabolic processGO:0006184710.031
cellular calcium ion homeostasisGO:00068741600.031
nucleoside metabolic processGO:00091161790.031
ribonucleoside triphosphate metabolic processGO:00091991410.030
protein polymerizationGO:0051258220.030
actin filament based processGO:0030029860.030
reproductionGO:00000032450.030
response to insulinGO:00328681330.030
divalent inorganic cation homeostasisGO:00725071650.029
negative regulation of protein metabolic processGO:00512481140.029
regulation of neurogenesisGO:00507672470.029
ribose phosphate metabolic processGO:00196932350.029
cell adhesionGO:00071551100.029
regulation of phosphorylationGO:00423252480.028
response to nutrient levelsGO:00316673700.028
response to oxygen levelsGO:00704822650.028
regulation of locomotionGO:00400121480.028
single organism organelle organizationGO:19025891800.028
cell cell signalingGO:00072673350.028
cellular divalent inorganic cation homeostasisGO:00725031620.028
purine nucleoside metabolic processGO:00422781690.028
calcium ion homeostasisGO:00550741620.027
biological adhesionGO:00226101100.027
rna metabolic processGO:00160704060.027
protein modification by small protein conjugation or removalGO:0070647350.027
developmental process involved in reproductionGO:00030061590.027
regulation of apoptotic processGO:00429813350.026
axon developmentGO:0061564960.026
response to woundingGO:00096112540.026
cellular response to peptide hormone stimulusGO:00713751200.026
regulation of response to stressGO:00801341260.026
telencephalon developmentGO:0021537620.026
carbohydrate derivative catabolic processGO:19011361470.025
circulatory system processGO:00030131830.025
organophosphate catabolic processGO:00464341480.025
single organism catabolic processGO:00447122830.025
regulation of protein kinase activityGO:00458591050.025
cellular metal ion homeostasisGO:00068751720.025
regulation of cell motilityGO:20001451310.025
response to monosaccharideGO:00342841590.025
positive regulation of phosphorylationGO:00423271770.025
regulation of neuron differentiationGO:00456642080.025
positive regulation of rna biosynthetic processGO:19026801970.024
apoptotic processGO:00069153810.024
lipid metabolic processGO:00066292830.024
regulation of protein transportGO:0051223680.024
regulation of multicellular organismal developmentGO:20000263760.024
chemotaxisGO:0006935660.024
salivary gland developmentGO:000743130.024
inorganic cation transmembrane transportGO:00986622020.024
cellular response to peptideGO:19016531330.024
protein targetingGO:0006605610.024
divalent metal ion transportGO:00708381320.024
axonogenesisGO:0007409710.024
regulation of protein polymerizationGO:0032271190.024
response to peptideGO:19016522920.024
positive regulation of neuron differentiationGO:00456661260.023
neurological system processGO:00508772190.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
negative regulation of response to stimulusGO:00485851550.023
central nervous system developmentGO:00074173110.023
guanosine containing compound catabolic processGO:1901069710.023
positive regulation of rna metabolic processGO:00512542030.023
positive regulation of catalytic activityGO:00430851840.023
divalent inorganic cation transportGO:00725111340.023
single organism biosynthetic processGO:00447113420.022
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.022
protein ubiquitinationGO:0016567280.022
cellular chemical homeostasisGO:00550822470.022
organonitrogen compound catabolic processGO:19015651790.022
behaviorGO:00076102050.022
Fly
nucleoside triphosphate metabolic processGO:00091411440.022
cell morphogenesis involved in differentiationGO:00009041190.022
positive regulation of cell deathGO:00109421840.022
purine ribonucleotide metabolic processGO:00091502270.022
response to growth factorGO:00708481890.022
locomotionGO:00400112370.022
regulation of dendrite developmentGO:0050773590.022
purine ribonucleoside triphosphate metabolic processGO:00092051400.022
purine containing compound catabolic processGO:00725231380.022
response to peptide hormoneGO:00434342780.022
cellular cation homeostasisGO:00300031800.022
cellular response to hormone stimulusGO:00328702470.021
calcium ion transportGO:00068161310.021
ribonucleoside triphosphate catabolic processGO:00092031220.021
forebrain developmentGO:0030900980.021
regulation of cell migrationGO:00303341280.021
regulation of hormone levelsGO:00108171870.021
regulation of cellular catabolic processGO:00313291010.021
regulation of cellular component biogenesisGO:0044087860.021
cell type specific apoptotic processGO:00972851340.021
response to hypoxiaGO:00016662310.021
monovalent inorganic cation transportGO:00156721720.021
mast cell migrationGO:009753140.021
regulation of axonogenesisGO:0050770370.021
aromatic compound catabolic processGO:00194391680.021
angiogenesisGO:0001525530.020
negative regulation of phosphorus metabolic processGO:0010563800.020
response to corticosteroidGO:00319602350.020
regulation of intracellular signal transductionGO:19025312180.020
negative regulation of biosynthetic processGO:00098901680.020
response to glucocorticoidGO:00513842230.020
g protein coupled receptor signaling pathwayGO:00071862420.020
multi organism reproductive processGO:00447032620.020
protein catabolic processGO:0030163300.020
synaptic transmissionGO:00072682350.020
cellular response to nitrogen compoundGO:19016992100.020
regulation of cell morphogenesisGO:0022604770.019
vasculature developmentGO:0001944700.019
protein importGO:0017038370.019
regulation of secretionGO:00510462240.019
regulation of mapk cascadeGO:00434081160.019
signal releaseGO:00230611450.019
single organism behaviorGO:00447081300.019
Fly
purine ribonucleoside catabolic processGO:00461301240.019
purine nucleoside catabolic processGO:00061521240.019
regulation of hydrolase activityGO:00513361430.019
organic hydroxy compound metabolic processGO:19016151150.019
intracellular protein transportGO:0006886790.019
multicellular organismal reproductive processGO:00486092330.019
regulation of membrane potentialGO:00423911100.019
axis specificationGO:000979840.019
cognitionGO:0050890920.018
cation transmembrane transportGO:00986552630.018
coenzyme metabolic processGO:0006732860.018
cellular response to oxygen containing compoundGO:19017013860.018
mapk cascadeGO:00001651400.018
asymmetric stem cell divisionGO:009872220.018
signal transduction by phosphorylationGO:00230141440.018
cardiac chamber developmentGO:000320510.018
single organism membrane organizationGO:0044802740.018
response to extracellular stimulusGO:00099913800.018
negative regulation of phosphate metabolic processGO:0045936800.018
positive regulation of apoptotic processGO:00430651540.018
organic cyclic compound catabolic processGO:19013611750.018
regulation of cellular component movementGO:00512701500.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
membrane organizationGO:0061024940.018
adult locomotory behaviorGO:000834440.018
establishment or maintenance of cell polarityGO:000716380.018
response to glucoseGO:00097491360.018
regulation of transferase activityGO:00513381230.018
organic hydroxy compound transportGO:0015850770.018
ribonucleoside catabolic processGO:00424541260.017
glycosyl compound catabolic processGO:19016581260.017
positive regulation of programmed cell deathGO:00430681570.017
microtubule organizing center organizationGO:003102310.017
motor neuron axon guidanceGO:000804510.017
dendrite morphogenesisGO:0048813430.017
negative regulation of molecular functionGO:00440921330.017
cellular response to insulin stimulusGO:0032869810.017
protein oligomerizationGO:00512591910.017
nucleoside catabolic processGO:00091641260.017
learning or memoryGO:0007611900.017
action potentialGO:0001508540.017
nucleic acid templated transcriptionGO:00976593790.017
cofactor metabolic processGO:0051186950.017
synaptic growth at neuromuscular junctionGO:005112410.017
positive regulation of cell developmentGO:00107201760.017
response to decreased oxygen levelsGO:00362932370.017
carboxylic acid transportGO:00469421150.017
neuron apoptotic processGO:0051402880.017
response to cytokineGO:00340972150.017
negative regulation of signal transductionGO:0009968830.017
positive regulation of cytosolic calcium ion concentrationGO:00072041220.016
regulation of nucleoside metabolic processGO:0009118660.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
regulation of metal ion transportGO:00109591180.016
embryonic axis specificationGO:000057810.016
regulation of gtpase activityGO:0043087570.016
positive regulation of locomotionGO:00400171020.016
macromolecule catabolic processGO:0009057580.016
heterocycle catabolic processGO:00467001670.016
purine ribonucleoside triphosphate catabolic processGO:00092071220.016
nucleobase containing compound catabolic processGO:00346551520.016
cellular nitrogen compound catabolic processGO:00442701630.016
gtp metabolic processGO:0046039720.016
positive regulation of cellular component movementGO:00512721020.016
small gtpase mediated signal transductionGO:0007264360.015
ribonucleotide catabolic processGO:00092611360.015
cellular macromolecular complex assemblyGO:0034622580.015
regulation of transmembrane transporter activityGO:0022898490.015
negative regulation of programmed cell deathGO:00430691830.015
response to nutrientGO:00075842480.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
spindle organizationGO:000705120.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
mitotic spindle organizationGO:000705220.015
gland developmentGO:00487321550.015
negative regulation of multicellular organismal processGO:00512412030.015
multicellular organism reproductionGO:00325042330.015
regulation of secretion by cellGO:19035302080.015
positive regulation of transportGO:00510502450.014
defense responseGO:00069521940.014
cell cycleGO:00070491010.014
cofactor biosynthetic processGO:0051188280.014
multicellular organismal homeostasisGO:0048871490.014
mitotic cell cycle processGO:1903047350.014
positive regulation of mapk cascadeGO:0043410920.014
response to hexoseGO:00097461440.014
multicellular organismal signalingGO:0035637440.014
positive regulation of secretion by cellGO:19035321280.014
regulation of muscle system processGO:0090257790.014
smooth muscle contractionGO:0006939370.014
cellular protein complex assemblyGO:0043623440.014
negative regulation of cellular protein metabolic processGO:00322691060.014
cell cycle phase transitionGO:0044770210.014
regulation of purine nucleotide metabolic processGO:19005421150.014
regulation of dendrite morphogenesisGO:0048814330.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.014
stress activated protein kinase signaling cascadeGO:0031098370.014
regulation of nucleotide metabolic processGO:00061401170.014
negative regulation of neurogenesisGO:0050768780.014
regulation of cellular component sizeGO:0032535510.014
regulation of intracellular transportGO:0032386650.014
response to biotic stimulusGO:00096072260.014
response to inorganic substanceGO:00100353770.013
positive regulation of dna metabolic processGO:0051054390.013
monocarboxylic acid metabolic processGO:00327871520.013
positive regulation of neuron apoptotic processGO:0043525330.013
regulation of vascular smooth muscle contractionGO:000305630.013
regulation of catabolic processGO:00098941130.013
somatic stem cell divisionGO:004810320.013
mitotic cell cycleGO:0000278490.013
regulation of anatomical structure morphogenesisGO:00226031410.013
positive regulation of cellular amine metabolic processGO:003324030.013
bone remodelingGO:0046849230.013
hormone transportGO:00099141210.013
development of primary sexual characteristicsGO:00451371070.013
actin filament depolymerizationGO:003004230.013
nucleoside phosphate catabolic processGO:19012921400.013
cortical actin cytoskeleton organizationGO:003086620.013
microtubule based processGO:0007017360.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
single organism reproductive processGO:00447022970.012
sexual reproductionGO:00199531480.012
cellular response to organonitrogen compoundGO:00714171970.012
rna localizationGO:000640340.012
growthGO:00400071650.012
golgi organizationGO:0007030170.012
neuron deathGO:00709971270.012
actin filament organizationGO:0007015420.012
peptidyl amino acid modificationGO:00181931260.012
epithelium developmentGO:0060429960.012
negative regulation of cellular component organizationGO:0051129830.012
purine ribonucleotide catabolic processGO:00091541360.012
response to bacteriumGO:00096172000.012
rho protein signal transductionGO:0007266110.012
sulfur compound metabolic processGO:0006790700.012
regulation of protein localizationGO:0032880810.012
positive regulation of neuron deathGO:1901216430.012
regulation of cell proliferationGO:00421273590.012
hormone secretionGO:00468791150.012
regulation of establishment of protein localizationGO:0070201690.012
regulation of homotypic cell cell adhesionGO:003411040.012
regulation of smooth muscle contractionGO:0006940290.012
negative regulation of transcription dna templatedGO:00458921160.012
maintenance of locationGO:0051235170.011
negative regulation of protein modification processGO:0031400520.011
regulation of blood circulationGO:19035221100.011
muscle tissue developmentGO:0060537580.011
spermatogenesisGO:0007283990.011
positive regulation of cell migrationGO:0030335960.011
response to heatGO:0009408600.011
cellular response to growth factor stimulusGO:00713631620.011
neuromuscular processGO:005090520.011
peptide transportGO:0015833970.011
negative regulation of actin filament polymerizationGO:003083740.011
amide transportGO:00428861050.011
regulation of metalloenzyme activityGO:004855210.011
transmission of nerve impulseGO:0019226420.011
neuron projection guidanceGO:0097485240.011
meiotic cell cycle processGO:190304630.011
tissue remodelingGO:0048771400.011
regulation of neuron deathGO:19012141150.011
regulation of cell adhesionGO:0030155520.011
bone resorptionGO:0045453180.011
positive regulation of protein kinase activityGO:0045860730.011
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.011
endocytosisGO:0006897840.011
regulation of proteasomal protein catabolic processGO:006113640.011
establishment of protein localization to organelleGO:0072594440.011
jnk cascadeGO:0007254280.011
actin polymerization or depolymerizationGO:0008154140.011
protein maturationGO:0051604680.011
salivary gland morphogenesisGO:000743510.011
single organismal cell cell adhesionGO:0016337420.010
regulation of transporter activityGO:0032409500.010
gamete generationGO:00072761240.010
centrosome cycleGO:000709810.010
regulation of ion transmembrane transportGO:00347651210.010
nucleotide catabolic processGO:00091661390.010
regulation of protein serine threonine kinase activityGO:0071900640.010
negative regulation of protein processingGO:0010955470.010
positive regulation of cell motilityGO:2000147970.010
cytosolic calcium ion homeostasisGO:00514801400.010
mast cell chemotaxisGO:000255140.010
positive regulation of secretionGO:00510471400.010
establishment of neuroblast polarityGO:004520010.010
regulation of growthGO:00400081050.010
centrosome organizationGO:005129710.010
response to other organismGO:00517072200.010
response to estradiolGO:00323551640.010
axon guidanceGO:0007411240.010
regulation of proteolysisGO:0030162660.010
regulation of cell cycleGO:0051726730.010
protein heterooligomerizationGO:0051291890.010

Rtn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
nervous system diseaseDOID:86300.037
sensory system diseaseDOID:005015500.013
disease of metabolismDOID:001466700.013