Rattus norvegicus

102 known processes

Pkp2

plakophilin 2

Pkp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
catabolic processGO:00090563510.072
organic acid metabolic processGO:00060822920.069
anatomical structure morphogenesisGO:00096532980.057
Human
cellular amino acid metabolic processGO:00065201070.056
blood circulationGO:00080151830.056
Human
carboxylic acid metabolic processGO:00197522890.055
organophosphate metabolic processGO:00196373700.054
response to inorganic substanceGO:00100353770.052
regulation of molecular functionGO:00650093980.050
oxoacid metabolic processGO:00434362900.049
transcription dna templatedGO:00063513770.047
positive regulation of developmental processGO:00510942830.047
negative regulation of metabolic processGO:00098923310.046
positive regulation of multicellular organismal processGO:00512403870.045
neuron developmentGO:00486662860.044
nucleic acid templated transcriptionGO:00976593790.043
organelle organizationGO:00069962660.042
Human
regulation of system processGO:00440572080.041
single organism catabolic processGO:00447122830.040
single organism biosynthetic processGO:00447113420.039
regulation of transcription dna templatedGO:00063553740.039
organonitrogen compound biosynthetic processGO:19015661670.039
nucleobase containing small molecule metabolic processGO:00550863160.038
neuron projection developmentGO:00311752730.038
neuron differentiationGO:00301823680.038
carbohydrate derivative metabolic processGO:19011353460.037
regulation of rna metabolic processGO:00512523910.037
regulation of catalytic activityGO:00507903040.037
rna metabolic processGO:00160704060.036
intracellular signal transductionGO:00355563140.036
rna biosynthetic processGO:00327743800.036
response to metal ionGO:00100382530.036
cell projection organizationGO:00300303020.035
regulation of membrane potentialGO:00423911100.034
response to peptide hormoneGO:00434342780.034
programmed cell deathGO:00125013920.034
regulation of ion transportGO:00432692450.034
organic substance catabolic processGO:19015753160.034
cellular amine metabolic processGO:0044106380.034
positive regulation of nucleobase containing compound metabolic processGO:00459353190.033
positive regulation of cellular biosynthetic processGO:00313282950.033
cellular component assemblyGO:00226073600.033
response to nutrientGO:00075842480.032
cellular response to oxygen containing compoundGO:19017013860.032
positive regulation of biosynthetic processGO:00098913190.032
regulation of cell proliferationGO:00421273590.032
response to nutrient levelsGO:00316673700.032
negative regulation of macromolecule metabolic processGO:00106052600.032
protein complex subunit organizationGO:00718223020.032
Human
lipid biosynthetic processGO:00086101280.032
cell morphogenesisGO:00009021420.032
regulation of nucleic acid templated transcriptionGO:19035063800.031
regulation of cellular ketone metabolic processGO:0010565270.031
cellular homeostasisGO:00197252520.031
regulation of cellular amino acid metabolic processGO:000652120.030
negative regulation of cellular metabolic processGO:00313242810.030
regulation of rna biosynthetic processGO:20011413810.030
regulation of neurogenesisGO:00507672470.030
cell part morphogenesisGO:00329901230.030
cellular response to endogenous stimulusGO:00714953770.030
nucleoside phosphate metabolic processGO:00067532830.030
central nervous system developmentGO:00074173110.029
Rat
ion homeostasisGO:00508012120.029
protein complex assemblyGO:00064612630.029
tissue developmentGO:00098882520.029
Human
cellular ketone metabolic processGO:0042180510.029
transmembrane transportGO:00550854120.029
positive regulation of gene expressionGO:00106282440.029
cellular component biogenesisGO:00440853680.029
ribonucleoside metabolic processGO:00091191740.029
nucleotide metabolic processGO:00091172790.029
regulation of cellular amine metabolic processGO:003323880.028
heart morphogenesisGO:000300730.028
Human
regulation of phosphate metabolic processGO:00192203490.028
response to oxygen levelsGO:00704822650.028
cellular cation homeostasisGO:00300031800.028
positive regulation of molecular functionGO:00440932300.028
response to corticosteroidGO:00319602350.028
secretionGO:00469033070.028
cellular response to peptide hormone stimulusGO:00713751200.028
regulation of cell differentiationGO:00455953200.028
Human
homeostatic processGO:00425923310.028
positive regulation of cell proliferationGO:00082842490.028
response to glucocorticoidGO:00513842230.027
cellular catabolic processGO:00442482950.027
cell projection morphogenesisGO:00488581230.027
regulation of multicellular organismal developmentGO:20000263760.027
amine metabolic processGO:0009308380.027
organonitrogen compound catabolic processGO:19015651790.027
regulation of programmed cell deathGO:00430673410.027
response to hypoxiaGO:00016662310.027
regulation of transcription from rna polymerase ii promoterGO:00063572340.027
ion transmembrane transportGO:00342203650.026
regulation of catabolic processGO:00098941130.026
oxidation reduction processGO:00551143040.026
cation transportGO:00068123820.026
ribose phosphate metabolic processGO:00196932350.026
transcription from rna polymerase ii promoterGO:00063662520.026
muscle contractionGO:0006936880.026
positive regulation of nitrogen compound metabolic processGO:00511733340.026
response to peptideGO:19016522920.026
coenzyme metabolic processGO:0006732860.026
negative regulation of gene expressionGO:00106291990.025
positive regulation of response to stimulusGO:00485842850.025
response to extracellular stimulusGO:00099913800.025
cell morphogenesis involved in neuron differentiationGO:00486671060.024
response to oxidative stressGO:00069791860.024
cardiac muscle contractionGO:0060048270.024
response to woundingGO:00096112540.024
negative regulation of response to stimulusGO:00485851550.024
cation homeostasisGO:00550801950.024
response to estrogenGO:00436272320.024
regulation of cellular localizationGO:00603412630.024
positive regulation of cell differentiationGO:00455972170.024
regulation of cellular component organizationGO:00511283680.023
regulation of phosphorus metabolic processGO:00511743490.023
nucleobase containing compound catabolic processGO:00346551520.023
regulation of signal transductionGO:00099663180.023
muscle system processGO:00030121150.023
nucleoside metabolic processGO:00091161790.023
immune system processGO:00023762040.023
cellular response to hormone stimulusGO:00328702470.023
positive regulation of cellular amine metabolic processGO:003324030.023
response to acid chemicalGO:00011012220.023
purine containing compound metabolic processGO:00725212530.022
regulation of nervous system developmentGO:00519602640.022
regulation of cell developmentGO:00602842630.022
purine nucleoside metabolic processGO:00422781690.022
nucleoside catabolic processGO:00091641260.022
negative regulation of biosynthetic processGO:00098901680.022
negative regulation of cellular biosynthetic processGO:00313271610.022
positive regulation of catalytic activityGO:00430851840.022
cell cell signalingGO:00072673350.022
Human
regulation of intracellular signal transductionGO:19025312180.022
response to ethanolGO:00454711620.022
neuron projection morphogenesisGO:00488121220.022
purine ribonucleotide metabolic processGO:00091502270.021
circulatory system processGO:00030131830.021
Human
response to decreased oxygen levelsGO:00362932370.021
chemical homeostasisGO:00488782920.021
cellular component morphogenesisGO:00329891550.021
ribonucleoside triphosphate metabolic processGO:00091991410.021
intracellular transportGO:00469071850.021
gland developmentGO:00487321550.021
purine ribonucleoside metabolic processGO:00461281680.021
negative regulation of cell communicationGO:00106481580.021
purine nucleotide metabolic processGO:00061632290.021
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
cellular component movementGO:00069282480.020
regulation of apoptotic processGO:00429813350.020
lipid metabolic processGO:00066292830.020
protein complex biogenesisGO:00702712630.020
positive regulation of cell developmentGO:00107201760.020
regulation of protein metabolic processGO:00512462890.020
negative regulation of multicellular organismal processGO:00512412030.020
heterocycle catabolic processGO:00467001670.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
positive regulation of cell communicationGO:00106472710.020
reproductive processGO:00224143720.020
regulation of hydrolase activityGO:00513361430.020
organic cyclic compound catabolic processGO:19013611750.020
response to ketoneGO:19016541820.019
response to monosaccharideGO:00342841590.019
cation transmembrane transportGO:00986552630.019
response to glucoseGO:00097491360.019
protein phosphorylationGO:00064683450.019
regulation of anatomical structure sizeGO:00900661350.019
cellular nitrogen compound catabolic processGO:00442701630.019
protein oligomerizationGO:00512591910.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
regulation of cellular protein metabolic processGO:00322682670.019
cellular chemical homeostasisGO:00550822470.019
monovalent inorganic cation transportGO:00156721720.019
single organism intracellular transportGO:19025821660.019
glycosyl compound catabolic processGO:19016581260.019
regulation of cellular catabolic processGO:00313291010.019
positive regulation of cellular component organizationGO:00511302000.019
positive regulation of phosphorus metabolic processGO:00105622620.019
secretion by cellGO:00329402480.019
cofactor metabolic processGO:0051186950.019
heart processGO:0003015570.019
Human
carbohydrate derivative catabolic processGO:19011361470.019
actin filament based processGO:0030029860.018
synaptic transmissionGO:00072682350.018
macromolecular complex assemblyGO:00650032730.018
single organism organelle organizationGO:19025891800.018
Human
cellular response to stressGO:00335542690.018
ventricular cardiac muscle cell action potentialGO:008600520.018
Human
glycosyl compound metabolic processGO:19016571820.018
aromatic compound catabolic processGO:00194391680.018
positive regulation of transcription dna templatedGO:00458931970.018
negative regulation of signalingGO:00230571570.018
regulation of anatomical structure morphogenesisGO:00226031410.018
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
regulation of secretionGO:00510462240.018
nucleoside triphosphate metabolic processGO:00091411440.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
ras protein signal transductionGO:0007265290.018
macromolecular complex subunit organizationGO:00439333390.018
Human
small gtpase mediated signal transductionGO:0007264360.018
response to carbohydrateGO:00097431830.018
positive regulation of transportGO:00510502450.018
metal ion homeostasisGO:00550651860.018
regulation of blood circulationGO:19035221100.018
cellular ion homeostasisGO:00068731840.017
purine nucleoside triphosphate catabolic processGO:00091461220.017
cell morphogenesis involved in differentiationGO:00009041190.017
neurological system processGO:00508772190.017
negative regulation of programmed cell deathGO:00430691830.017
regulation of hormone levelsGO:00108171870.017
regulation of secretion by cellGO:19035302080.017
divalent inorganic cation homeostasisGO:00725071650.017
single organism reproductive processGO:00447022970.017
positive regulation of signalingGO:00230562700.017
dna metabolic processGO:0006259960.017
purine ribonucleotide catabolic processGO:00091541360.017
axon developmentGO:0061564960.017
circulatory system developmentGO:00723591340.017
Human
agingGO:00075682410.017
cellular response to growth factor stimulusGO:00713631620.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
purine nucleoside triphosphate metabolic processGO:00091441410.017
response to vitaminGO:00332731310.017
regulation of cell projection organizationGO:00313441750.017
cellular response to organic cyclic compoundGO:00714072020.017
inorganic ion transmembrane transportGO:00986602290.016
negative regulation of cell proliferationGO:00082851190.016
regulation of phosphorylationGO:00423252480.016
purine containing compound catabolic processGO:00725231380.016
purine ribonucleoside catabolic processGO:00461301240.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
cellular metal ion homeostasisGO:00068751720.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
response to insulinGO:00328681330.016
ribonucleotide metabolic processGO:00092592310.016
positive regulation of rna metabolic processGO:00512542030.016
negative regulation of phosphate metabolic processGO:0045936800.016
response to reactive oxygen speciesGO:00003021200.016
heart contractionGO:0060047570.016
Human
ribonucleoside catabolic processGO:00424541260.016
organic acid biosynthetic processGO:0016053830.016
axis specificationGO:000979840.016
cellular calcium ion homeostasisGO:00068741600.016
action potentialGO:0001508540.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
regulation of purine nucleotide metabolic processGO:19005421150.016
regulation of neuron projection developmentGO:00109751610.016
positive regulation of nervous system developmentGO:00519621780.016
regulation of metal ion transportGO:00109591180.016
wound healingGO:00420601220.015
regulation of homeostatic processGO:00328441010.015
negative regulation of molecular functionGO:00440921330.015
gastrulationGO:000736920.015
organophosphate biosynthetic processGO:00904071430.015
organ morphogenesisGO:0009887750.015
Human
response to hexoseGO:00097461440.015
cellular lipid metabolic processGO:00442552080.015
actin cytoskeleton organizationGO:0030036730.015
positive regulation of phosphorylationGO:00423271770.015
positive regulation of cell projection organizationGO:00313461110.015
negative regulation of cell deathGO:00605482290.015
multicellular organismal signalingGO:0035637440.015
monocarboxylic acid metabolic processGO:00327871520.015
negative regulation of rna biosynthetic processGO:19026791180.015
anion transportGO:00068201780.015
regulation of protein modification processGO:00313991940.015
dephosphorylationGO:0016311980.015
positive regulation of rna biosynthetic processGO:19026801970.015
nucleoside phosphate catabolic processGO:19012921400.015
sex differentiationGO:00075481130.014
mesoderm developmentGO:000749820.014
regulation of transmembrane transportGO:00347621220.014
cellular macromolecule localizationGO:00707271220.014
divalent metal ion transportGO:00708381320.014
regulation of response to external stimulusGO:00321011060.014
protein transportGO:00150311320.014
regulation of nucleotide metabolic processGO:00061401170.014
nucleotide catabolic processGO:00091661390.014
negative regulation of signal transductionGO:0009968830.014
regulation of neuron differentiationGO:00456642080.014
metal ion transportGO:00300012890.014
positive regulation of protein metabolic processGO:00512471780.014
negative regulation of rna metabolic processGO:00512531230.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
negative regulation of protein metabolic processGO:00512481140.014
developmental process involved in reproductionGO:00030061590.014
multi multicellular organism processGO:00447061380.014
apoptotic processGO:00069153810.014
signal transduction by phosphorylationGO:00230141440.014
cellular response to nitrogen compoundGO:19016992100.014
defense responseGO:00069521940.014
salivary gland developmentGO:000743130.014
multicellular organismal reproductive processGO:00486092330.014
head developmentGO:00603222470.014
Rat
multi organism reproductive processGO:00447032620.014
positive regulation of catabolic processGO:0009896780.013
chromosome segregationGO:000705920.013
protein localizationGO:00081041910.013
negative regulation of phosphorus metabolic processGO:0010563800.013
purine nucleotide catabolic processGO:00061951360.013
cardiac conductionGO:006133720.013
developmental growthGO:00485891000.013
nucleoside triphosphate catabolic processGO:00091431230.013
regulation of mapk cascadeGO:00434081160.013
muscle structure developmentGO:0061061870.013
Human
purine nucleoside catabolic processGO:00061521240.013
macromolecule localizationGO:00330362520.013
regulation of response to stressGO:00801341260.013
carbohydrate metabolic processGO:00059751300.013
cellular response to lipidGO:00713962010.013
regenerationGO:00310991630.013
negative regulation of cellular protein metabolic processGO:00322691060.013
growthGO:00400071650.013
regulation of muscle system processGO:0090257790.013
Human
carboxylic acid biosynthetic processGO:0046394830.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
divalent inorganic cation transportGO:00725111340.013
reproductionGO:00000032450.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
multicellular organism reproductionGO:00325042330.013
brain developmentGO:00074202470.013
Rat
positive regulation of neurogenesisGO:00507691650.013
calcium ion homeostasisGO:00550741620.013
negative regulation of cardiac muscle tissue developmentGO:005502630.013
anterior posterior pattern specificationGO:000995210.013
regulation of protein phosphorylationGO:00019321830.012
hepaticobiliary system developmentGO:0061008900.012
positive regulation of phosphate metabolic processGO:00459372620.012
positive regulation of mapk cascadeGO:0043410920.012
response to biotic stimulusGO:00096072260.012
reactive oxygen species metabolic processGO:0072593370.012
reactive nitrogen species metabolic processGO:200105710.012
response to bacteriumGO:00096172000.012
cardiac muscle cell contractionGO:0086003100.012
regulation of neuron deathGO:19012141150.012
camera type eye developmentGO:0043010480.012
regulation of ion transmembrane transportGO:00347651210.012
cell type specific apoptotic processGO:00972851340.012
regulation of cell morphogenesisGO:0022604770.012
locomotionGO:00400112370.012
positive regulation of neuron differentiationGO:00456661260.012
axonogenesisGO:0007409710.012
cellular response to oxidative stressGO:0034599760.012
response to estradiolGO:00323551640.012
carbohydrate derivative biosynthetic processGO:19011371240.012
regulation of synaptic transmissionGO:00508041410.012
regulation of kinase activityGO:00435491170.012
signal releaseGO:00230611450.012
regulation of body fluid levelsGO:0050878900.012
organophosphate catabolic processGO:00464341480.012
tube developmentGO:0035295890.011
cytosolic calcium ion homeostasisGO:00514801400.011
cellular response to abiotic stimulusGO:0071214850.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
regulation of gtpase activityGO:0043087570.011
positive regulation of secretion by cellGO:19035321280.011
positive regulation of intracellular signal transductionGO:19025331380.011
response to cytokineGO:00340972150.011
inorganic cation transmembrane transportGO:00986622020.011
chemosensory behaviorGO:000763520.011
cellular response to organonitrogen compoundGO:00714171970.011
negative regulation of transportGO:00510511360.011
cell migrationGO:00164771970.011
embryonic pattern specificationGO:000988010.011
reactive oxygen species biosynthetic processGO:190340980.011
gonad developmentGO:00084061040.011
eye morphogenesisGO:004859240.011
negative regulation of apoptotic processGO:00430661810.011
striated muscle tissue developmentGO:0014706580.011
Human
organic anion transportGO:00157111320.011
appendage morphogenesisGO:003510740.011
response to transition metal nanoparticleGO:19902671220.011
liver developmentGO:0001889900.011
positive regulation of blood circulationGO:1903524650.011
cell motilityGO:00488702020.011
amide transportGO:00428861050.011
positive regulation of signal transductionGO:00099671750.011
regulation of canonical wnt signaling pathwayGO:006082840.011
cardiovascular system developmentGO:00723581340.011
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
negative regulation of organ growthGO:004662130.011
response to growth factorGO:00708481890.011
localization of cellGO:00516742020.011
gliogenesisGO:0042063930.011
regulation of tube sizeGO:0035150890.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
positive regulation of cellular catabolic processGO:0031331710.010
cellular response to fluid shear stressGO:007149840.010
reproductive structure developmentGO:00486081280.010
response to toxic substanceGO:00096361330.010
positive regulation of hydrolase activityGO:0051345860.010
actin filament based movementGO:0030048160.010
negative regulation of catalytic activityGO:00430861030.010
muscle organ developmentGO:0007517500.010
Human
glomerular epithelial cell differentiationGO:007231120.010
cellular response to external stimulusGO:00714961180.010
male gamete generationGO:0048232990.010
nucleoside phosphate biosynthetic processGO:19012931020.010
anatomical structure formation involved in morphogenesisGO:0048646830.010
sexual reproductionGO:00199531480.010
response to mineralocorticoidGO:0051385490.010
ribonucleotide catabolic processGO:00092611360.010
negative regulation of heart growthGO:006111730.010
positive regulation of protein modification processGO:00314011420.010
mapk cascadeGO:00001651400.010
lipid storageGO:001991510.010
regulation of cellular component biogenesisGO:0044087860.010
proteolysisGO:00065081750.010
vesicle mediated transportGO:00161921810.010

Pkp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.024
disease of anatomical entityDOID:700.024
Human
musculoskeletal system diseaseDOID:1700.023
Human
muscular diseaseDOID:008000000.023
Human
heart diseaseDOID:11400.017
Human
cardiovascular system diseaseDOID:128700.017
Human
intrinsic cardiomyopathyDOID:006003600.013
Human
cardiomyopathyDOID:005070000.013
Human
myopathyDOID:42300.013
Human
muscle tissue diseaseDOID:6600.013
Human
sensory system diseaseDOID:005015500.012
disease of metabolismDOID:001466700.011